|
|
3-Mercaptopyruvate + thioredoxin <=> pyruvate + Sulfide + thioredoxin_disulfide
|
2.8.1.2
3-mercaptopyruvate sulfurtransferase
|
–
|
MK
|
|
BRENDA:
BR48100
KEGG:
R03105
MetaCyc:
MERCAPYSTRANS-RXN
|
|
|
|
[3-mercaptopyruvate_sulfurtransferase]-S-sulfanyl-L-cysteine + thioredoxin <=> [3-mercaptopyruvate_sulfurtransferase]-L-cysteine + Sulfide + thioredoxin_disulfide
|
2.8.1.2
3-mercaptopyruvate sulfurtransferase
|
–
|
|
|
BRENDA:
BR52329
MetaCyc:
RXN-18703
|
|
|
|
2''-deoxyribonucleoside_5''-triphosphate + thioredoxin_disulfide + H2O <=> NTP + thioredoxin
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
|
|
BRENDA:
BR40369;
BS287778;
BS287786
KEGG:
R04315
MetaCyc:
1.17.4.2-RXN
|
|
|
|
dATP + thioredoxin_disulfide + H2O <=> ATP + thioredoxin
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
BK
|
|
BRENDA:
BS287787
KEGG:
R02014
MetaCyc:
RXN-21262
SABIO-RK:
2051
|
|
|
|
dGTP + thioredoxin_disulfide + H2O <=> GTP + thioredoxin
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
BK
|
|
BRENDA:
BS287788
KEGG:
R02020
MetaCyc:
RXN-21263
SABIO-RK:
2052
|
|
|
|
dCTP + thioredoxin_disulfide + H2O <=> CTP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
K
|
|
BRENDA:
BS287789
KEGG:
R02022
MetaCyc:
RXN-21264
SABIO-RK:
491
|
|
|
|
dUTP + thioredoxin_disulfide + H2O <=> UTP + thioredoxin
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
K
|
|
BRENDA:
BS287790
KEGG:
R02023
MetaCyc:
RXN-21265
|
|
|
|
dADP + thioredoxin_disulfide + H2O <=> ADP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
BMK
|
|
BRENDA:
BS287791
KEGG:
R02017
MetaCyc:
ADPREDUCT-RXN
|
|
|
|
dCDP + thioredoxin_disulfide + H2O <=> CDP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
BMK
|
|
BRENDA:
BS287792
KEGG:
R02024
MetaCyc:
CDPREDUCT-RXN
SABIO-RK:
240
|
|
|
|
dUDP + thioredoxin_disulfide + H2O <=> UDP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
BMK
|
|
BRENDA:
BS287795
KEGG:
R02018
MetaCyc:
UDPREDUCT-RXN
|
|
|
|
dGDP + thioredoxin_disulfide + H2O <=> GDP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
BMK
|
|
BRENDA:
BS287796
KEGG:
R02019
MetaCyc:
GDPREDUCT-RXN
|
|
|
|
thioredoxin + H2O2 <=> thioredoxin_disulfide + H2O
|
1.11.1.15
peroxiredoxin
1.11.1.20
prostamide/prostaglandin F2alpha synthase
1.11.1.24
thioredoxin-dependent peroxiredoxin
1.11.1.25
glutaredoxin-dependent peroxiredoxin
1.11.1.7
peroxidase
|
–
–
–
–
–
|
B
|
|
BRENDA:
BS373387
MetaCyc:
RXN0-267
SABIO-RK:
11213
|
|
|
|
adenosine_3,5''-bisphosphate + sulfite + thioredoxin_disulfide + H+ <=> 3''-phosphoadenylyl-sulfate + thioredoxin
|
1.8.4.8
phosphoadenylyl-sulfate reductase (thioredoxin)
|
–
|
MK
|
|
BRENDA:
BR15888
KEGG:
R02021
MetaCyc:
1.8.4.8-RXN
|
|
|
|
L-methionine + thioredoxin_disulfide + H2O <=> methionine_sulfoxide + thioredoxin
|
1.8.4.13
L-methionine (S)-S-oxide reductase
1.8.4.14
L-methionine (R)-S-oxide reductase
1.8.4.5
methionine-S-oxide reductase
|
–
–
–
|
K
|
|
BRENDA:
BR36934
KEGG:
R02025
|
|
|
|
thioredoxin + NADP+ <=> thioredoxin_disulfide + NADPH + H+
|
1.8.1.9
thioredoxin-disulfide reductase
1.8.1.B1
|
–
–
|
M
|
|
BRENDA:
BR37017
KEGG:
R02016
MetaCyc:
THIOREDOXIN-REDUCT-NADPH-RXN
SABIO-RK:
489
|
|
|
|
2''-deoxyribonucleoside_5''-diphosphate + thioredoxin_disulfide + H2O <=> NDP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
|
–
|
|
|
BRENDA:
BR40370
KEGG:
R04294
MetaCyc:
RIBONUCLEOSIDE-DIP-REDUCTI-RXN
|
|
|
|
acetyl_phosphate + methylamine + H2O + thioredoxin_disulfide <=> sarcosine + phosphate + thioredoxin + H+
|
1.21.4.3
sarcosine reductase
|
–
|
|
|
BRENDA:
BR47363
KEGG:
R07227
MetaCyc:
1.21.4.3-RXN
|
|
|
|
acetyl_phosphate + NH3 + thioredoxin_disulfide + H2O <=> glycine + phosphate + thioredoxin + H+
|
1.21.4.2
glycine reductase
|
–
|
BM
|
|
BRENDA:
BR47373
KEGG:
R07226
MetaCyc:
RXN-7566
|
|
|
|
acetyl_phosphate + trimethylamine + H2O + thioredoxin_disulfide <=> betaine + phosphate + thioredoxin + H+
|
1.21.4.4
betaine reductase
|
–
|
|
|
BRENDA:
BR47375
KEGG:
R07228
MetaCyc:
1.21.4.4-RXN
|
|
|
|
sulfite + AMP + thioredoxin_disulfide + H+ <=> adenosine_5''-phosphosulfate + thioredoxin
|
1.8.4.10
adenylyl-sulfate reductase (thioredoxin)
1.8.4.8
phosphoadenylyl-sulfate reductase (thioredoxin)
1.8.4.9
adenylyl-sulfate reductase (glutathione)
1.8.99.2
adenylyl-sulfate reductase
|
–
–
–
–
|
M
|
|
BRENDA:
BR47380
KEGG:
R07176
MetaCyc:
RXN-12019
|
|
|
|
L-methionine + thioredoxin_disulfide + H2O <=> L-methionine_(R)-S-oxide + thioredoxin
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
1.8.4.14
L-methionine (R)-S-oxide reductase
1.8.4.B3
|
–
–
–
–
|
B
|
|
BRENDA:
BR48616
KEGG:
R07608
MetaCyc:
1.8.4.14-RXN
|
|
|
|
L-methionine + thioredoxin_disulfide + H2O <=> L-methionine_(S)-sulfoxide + thioredoxin
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
1.8.4.13
L-methionine (S)-S-oxide reductase
|
–
–
–
|
|
|
BRENDA:
BR48617
KEGG:
R07606
MetaCyc:
1.8.4.13-RXN
|
|
|
|
peptide-L-methionine + thioredoxin_disulfide + H2O <=> peptide-L-methionine_(S)-S-oxide + thioredoxin
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
–
|
|
|
BRENDA:
BR48820
KEGG:
R04120
|
|
|
|
peptide-L-methionine + thioredoxin_disulfide + H2O <=> peptide-L-methionine-(R)-S-sulfoxide + thioredoxin
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BR48821
KEGG:
R07607
|
|
|
|
reduced_ferredoxin_[iron-sulfur]_cluster + thioredoxin_disulfide + H+ <=> oxidized_ferredoxin + thioredoxin
|
1.8.7.2
ferredoxin:thioredoxin reductase
|
–
|
|
|
BRENDA:
BR49236
KEGG:
R09502
MetaCyc:
RXN-9944
|
|
|
|
arsenate + thioredoxin + H+ <=> arsenite + thioredoxin_disulfide + H2O
|
1.20.4.1
arsenate reductase (glutathione/glutaredoxin)
1.20.4.4
arsenate reductase (thioredoxin)
|
–
–
|
M
|
|
BRENDA:
BR49274
KEGG:
R10927
MetaCyc:
RXN-10737
SABIO-RK:
13362
|
|
|
|
thioredoxin + prostaglandin_H2 <=> thioredoxin_disulfide + prostaglandin_F2alpha
|
1.11.1.20
prostamide/prostaglandin F2alpha synthase
|
–
|
MK
|
|
BRENDA:
BR49412
KEGG:
R09506
MetaCyc:
RXN-12122
SABIO-RK:
15153
|
|
|
|
thioredoxin + ROOH <=> thioredoxin_disulfide + H2O + an_alcohol
|
1.11.1.24
thioredoxin-dependent peroxiredoxin
1.11.1.25
glutaredoxin-dependent peroxiredoxin
|
–
–
|
|
|
BRENDA:
BR53019
KEGG:
R12570
MetaCyc:
1.11.1.15-RXN
|
|
|
|
arsenate + reduced_glutaredoxin <=> arsenite + thioredoxin_disulfide
|
1.20.4.1
arsenate reductase (glutathione/glutaredoxin)
|
–
|
B
|
|
BRENDA:
BS355979
SABIO-RK:
5340
|
|
|
|
cumene_hydroperoxide + thioredoxin <=> 2-phenylpropan-2-ol + thioredoxin_disulfide + H2O
|
1.11.1.15
peroxiredoxin
1.11.1.20
prostamide/prostaglandin F2alpha synthase
1.11.1.24
thioredoxin-dependent peroxiredoxin
1.11.1.7
peroxidase
|
–
–
–
–
|
|
|
BRENDA:
BS372785
SABIO-RK:
11214
|
|
|
|
tert-butyl_hydroperoxide + thioredoxin <=> tert-butanol + thioredoxin_disulfide + H2O
|
1.11.1.15
peroxiredoxin
1.11.1.20
prostamide/prostaglandin F2alpha synthase
1.11.1.24
thioredoxin-dependent peroxiredoxin
1.11.1.25
glutaredoxin-dependent peroxiredoxin
|
–
–
–
–
|
|
|
BRENDA:
BS374700
SABIO-RK:
11215
|
|
|
|
prostamide_H2 + thioredoxin <=> prostamide_F2alpha + thioredoxin_disulfide
|
1.11.1.20
prostamide/prostaglandin F2alpha synthase
|
–
|
|
|
BRENDA:
BS398197
SABIO-RK:
15152
|
|
|
|
O-acetyl-L-homoserine + thiosulfate + thioredoxin + H+ <=> L-homocysteine + sulfite + thioredoxin_disulfide + acetate
|
not assigned
|
–
|
K
|
|
KEGG:
R02026
|
|
|
|
O-acetyl-L-serine + thiosulfate + thioredoxin + H+ <=> L-cysteine + sulfite + thioredoxin_disulfide + acetate
|
2.5.1.47
cysteine synthase
2.5.1.49
O-acetylhomoserine aminocarboxypropyltransferase
|
–
–
|
|
|
KEGG:
R04859
|
|
|
|
arsenate + thioredoxin <=> arsenite + thioredoxin_disulfide
|
1.20.4.1
arsenate reductase (glutathione/glutaredoxin)
|
–
|
|
|
KEGG:
R05747
|
|
|
|
S-sulfocysteine + thioredoxin <=> L-cysteine + sulfite + thioredoxin_disulfide
|
not assigned
|
–
|
K
|
|
KEGG:
R10409
|
|
|
|
5-fluorodeoxyuridine_5'-diphosphate + thioredoxin_disulfide + H2O <=> 5-Fluorouridine_diphosphate + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
|
–
|
K
|
|
KEGG:
R11893
|
|
|
|
thioredoxin + ROOH <=> thioredoxin_disulfide + H2O + rhodopsin
|
1.11.1.25
glutaredoxin-dependent peroxiredoxin
|
–
|
|
|
KEGG:
R12571
|
|
|
|
peptide-L-methionine + thioredoxin_disulfide + H2O <=> peptide-L-methionine-(R)-S-sulfoxide + thioredoxin
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
MetaCyc:
1.8.4.12-RXN
|
|
|
|
S-adenosyl-L-methionine + arsenic_triglutathione + H2O + thioredoxin <=> dimethylarsinous_acid + S-adenosyl-L-homocysteine + glutathione + thioredoxin_disulfide
|
2.1.1.137
arsenite methyltransferase
|
–
|
M
|
|
MetaCyc:
2.1.1.137-RXN
|
|
|
|
glutathione + thioredoxin_disulfide <=> GSSG + reduced_glutaredoxin
|
not assigned
|
–
|
M
|
|
MetaCyc:
PRODISULFREDUCT-A-RXN
|
|
|
|
S-sulfocysteine + reduced_glutaredoxin <=> L-cysteine + sulfite + thioredoxin_disulfide + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18586
|
|
|
|
oxidized_DsbC_protein + thioredoxin <=> reduced_DsbC_protein + thioredoxin_disulfide
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20017
|
|
|
|
thioredoxin_disulfide + a_[DsbD_protein]_with_reduced_L-cysteine_residues <=> thioredoxin + a_[DsbD_protein]_carrying_a_disulfide_bond
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
M
|
|
MetaCyc:
RXN-20161
|
|
|
|
reduced_glutaredoxin + ROOH <=> thioredoxin_disulfide + H2O + an_alcohol
|
1.11.1.25
glutaredoxin-dependent peroxiredoxin
|
–
|
|
|
MetaCyc:
RXN-20687
|
|
|
|
reduced_glutaredoxin + [2-Cys_peroxiredoxin]_with_a_disulfide_bond <=> thioredoxin_disulfide + [2-Cys_peroxiredoxin]_with_reduced_L-cysteine_residues
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20688
|
|
|
|
S-adenosyl-L-methionine + dimethylarsinous_acid + thioredoxin <=> S-adenosyl-L-homocysteine + trimethylarsine + H2O + thioredoxin_disulfide + H+
|
2.1.1.137
arsenite methyltransferase
|
–
|
|
|
MetaCyc:
RXN-21028
|
|
|
|
S-adenosyl-L-methionine + methylarsonite + thioredoxin <=> S-adenosyl-L-homocysteine + dimethylarsinous_acid + H2O + thioredoxin_disulfide + H+
|
2.1.1.137
arsenite methyltransferase
|
–
|
|
|
MetaCyc:
RXN-21029
|
|
|
|
ResA_protein_with_reduced_cysteine_residues + thioredoxin_disulfide <=> ResA_protein_with_an_internal_disulfide_bridge + thioredoxin
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
M
|
|
MetaCyc:
RXN-21406
|
|
|
|
peptide-L-methionine + thioredoxin_disulfide + H2O <=> peptide-L-methionine_(S)-S-oxide + thioredoxin
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
MetaCyc:
RXN-8668
|
|
|
|
thioredoxin + [2-Cys_peroxiredoxin]_with_a_disulfide_bond <=> thioredoxin_disulfide + [2-Cys_peroxiredoxin]_with_reduced_L-cysteine_residues
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-5468
|
|
|
|
biotin_sulfoxide + thioredoxin <=> biotin + thioredoxin_disulfide + H2O
|
1.8.4
|
–
|
|
|
MetaCyc:
RXN0-6277
|
|
|
|
thiosulfate + thioredoxin <=> thioredoxin_disulfide + sulfite + Sulfide + H+
|
2.8.1
|
–
|
|
|
MetaCyc:
RXN0-6385
|
|
|
|
a_protein_with_a_disulfide_bond + reduced_glutaredoxin <=> a_protein_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN0-7271
|
|
|
|
a_[DsbD_protein]_with_reduced_L-cysteine_residues + thioredoxin_disulfide <=> a_[DsbD_protein]_carrying_a_disulfide_bond + thioredoxin
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
MetaCyc:
RXN0-7311
|
|
|
|
thioredoxin_disulfide + reduced_acceptor <=> thioredoxin + acceptor
|
not assigned
|
–
|
M
|
|
MetaCyc:
THIOREDOXIN-RXN
|
|
|
|
thioredoxin + O2 <=> thioredoxin_disulfide + H2O2
|
1.8.3.2
thiol oxidase
|
–
|
|
|
BRENDA:
BS377876
|
|
|
|
thioredoxin + linoleic_acid_hydroperoxide <=> thioredoxin_disulfide + H2O + linoleic_acid
|
1.11.1.24
thioredoxin-dependent peroxiredoxin
|
–
|
|
|
BRENDA:
BS448989
|
|
|
|
thioredoxin + 1,4-benzoquinone <=> thioredoxin_disulfide + H2O + hydroquinone
|
1.11.1.25
glutaredoxin-dependent peroxiredoxin
|
–
|
|
|
BRENDA:
BS449975
|
|
|
|
NDP + reduced_glutaredoxin <=> 2''-deoxyribonucleoside_diphosphate + thioredoxin_disulfide + H2O
|
1.17.4.1
ribonucleoside-diphosphate reductase
|
–
|
|
|
BRENDA:
BS287813
|
|
|
|
2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + thioredoxin <=> vitamin_K + thioredoxin_disulfide
|
1.17.4.4
vitamin-K-epoxide reductase (warfarin-sensitive)
|
–
|
|
|
BRENDA:
BS427885
|
|
|
|
calmodulin_L-methionine-(S)-sulfoxide + thioredoxin <=> calmodulin-L-methionine + thioredoxin_disulfide
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS375083
|
|
|
|
calmodulin-L-methionine_(R)-sulfoxide + thioredoxin <=> calmodulin-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS375082
|
|
|
|
Tyr-Gly-Gly-Phe-L-methionine-(S)-S-oxide + thioredoxin <=> Met-enkephalin + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS383397
|
|
|
|
thioredoxin + 3-acetylpyridine_adenine_dinucleotide <=> thioredoxin_disulfide + reduced_acetylpyridine_adenine_dinucleotide
|
1.8.1.9
thioredoxin-disulfide reductase
|
–
|
|
|
BRENDA:
BS260493
|
|
|
|
ITP + thioredoxin <=> dITP + thioredoxin_disulfide
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
|
|
BRENDA:
BS287797
|
|
|
|
Dimethylsulfide + thioredoxin_disulfide + H2O <=> dimethylsulfoxide_(S)-S-oxide + thioredoxin
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS441322
|
|
|
|
dabsyl-L-methionine_(R)-sulfoxide + thioredoxin <=> dabsyl-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
–
|
|
|
BRENDA:
BS376644
|
|
|
|
dabsyl-L-methionine-(S)-S-oxide + thioredoxin <=> dabsyl-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS384565
|
|
|
|
dabsyl-L-methionine_(S)-sulfoxide + thioredoxin <=> dabsyl-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS376643
|
|
|
|
sulindac + thioredoxin <=> sulindac_sulfide + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
–
|
|
|
BRENDA:
BS375321
|
|
|
|
DL-methionine_(R)-sulfoxide + thioredoxin <=> DL-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
–
|
|
|
BRENDA:
BS376729
|
|
|
|
ribosomal_protein_L12-L-methionine_(S)-sulfoxide + thioredoxin <=> ribosomal_protein_L12-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS375277
|
|
|
|
N-acetyl-L-methionine_(S)-sulfoxide_methyl_ester + thioredoxin <=> N-acetyl-L-methionine_methyl_ester + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS377209
|
|
|
|
N-acetyl-L-methionine-methyl_ester_(RS)-sulfoxide + thioredoxin <=> N-acetyl-L-methionine_methyl_ester + thioredoxin_disulfide
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS376187
|
|
|
|
IDP + thioredoxin <=> dIDP + thioredoxin_disulfide
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
|
|
BRENDA:
BS287798
|
|
|
|
UMP + thioredoxin <=> dUMP + thioredoxin_disulfide + H2O
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
|
|
BRENDA:
BS287794
|
|
|
|
thioredoxin + insulin_disulfide <=> thioredoxin_disulfide + Insulin
|
1.8.1.9
thioredoxin-disulfide reductase
|
–
|
|
|
BRENDA:
BS406759
|
|
|
|
oxidized_calmodulin + thioredoxin <=> partially_reduced_calmodulin + thioredoxin_disulfide
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
–
|
|
|
BRENDA:
BS377432
|
|
|
|
CDP + thioredoxin <=> 2''-deoxy-CDP + thioredoxin_disulfide + H2O
|
1.17.4.1
ribonucleoside-diphosphate reductase
|
–
|
|
|
BRENDA:
BS287801
|
|
|
|
alpha-synuclein-L-methionine_(S)-S-oxide + thioredoxin <=> alpha-synuclein-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS396398
|
|
|
|
thioredoxin + prostamide_H2 <=> thioredoxin_disulfide + (5Z,9alpha,11alpha,13E,15S)-9,11,15-trihydroxy-N-(2-hydroxyethyl)prosta-5,13-dien-1-amide
|
1.11.1.20
prostamide/prostaglandin F2alpha synthase
|
–
|
|
|
BRENDA:
BS411031
|
|
|
|
protein-L-methionine_(S)-sulfoxide + thioredoxin <=> peptide-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS375260
|
|
|
|
tubercidin_diphosphate + thioredoxin <=> 2''-deoxytubercidin_diphosphate + thioredoxin_disulfide + H2O
|
1.17.4.1
ribonucleoside-diphosphate reductase
|
–
|
|
|
BRENDA:
BS287808
|
|
|
|
acetyl-L-methionine-(S)-S-oxide-NHMe + thioredoxin <=> acetyl-L-methionine-NHMe + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS441000
|
|
|
|
methionine_sulfoxide_in_alkyl_hydroperoxide_reductase_C + thioredoxin <=> methionine_in_alkyl_hydroperoxide_reductase_C + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS441607
|
|
|
|
acetyl-L-methionine_(R)-sulfoxide_N-methyl_ester + thioredoxin <=> L-methionine_methyl_ester + thioredoxin_disulfide + H2O
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS451780
|
|
|
|
acetyl-L-methionine_(R)-sulfoxide_methyl_ester + thioredoxin <=> L-methionine_methyl_ester + thioredoxin_disulfide + H2O
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS376186
|
|
|
|
a_[DsbD_protein]_with_reduced_L-cysteine_residues + thioredoxin_disulfide <=> a_[DsbD_protein]_carrying_a_disulfide_bond + thioredoxin
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BR52975
|
|
|
|
protein-dithiol + thioredoxin_disulfide <=> protein_disulfide + thioredoxin
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BR52974
|
|
|
|
dabsylated_L-methionine_(S)-sulfoxide + thioredoxin <=> dabsylated_L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS451779
|
|
|
|
[CcmG_protein]_carrying_a_disulfide_bond + thioredoxin <=> [CcmG_protein]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454698
|
|
|
|
[DsbC_protein]_carrying_a_disulfide_bond + thioredoxin <=> [DsbC_protein]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454709
|
|
|
|
[DsbC_protein]_carrying_a_disulfide_bond + thioredoxin <=> [DsbC]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454710
|
|
|
|
[DsbE_protein]_carrying_a_disulfide_bond + thioredoxin <=> [DsbE_protein]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454712
|
|
|
|
[DsbG_protein]_carrying_a_disulfide_bond + thioredoxin <=> [DsbG_protein]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454713
|
|
|
|
[HelX_protein]_carrying_a_disulfide_bond + thioredoxin <=> [HelX_protein]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454717
|
|
|
|
[protein_DsbC]_carrying_a_disulfide_bond + thioredoxin <=> [protein_DsbC]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454732
|
|
|
|
[protein_DsbE]_carrying_a_disulfide_bond + thioredoxin <=> [protein_DsbE]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454733
|
|
|
|
[protein_DsbG]_carrying_a_disulfide_bond + thioredoxin <=> [protein_DsbG]_with_reduced_L-cysteine_residues + thioredoxin_disulfide
|
1.8.4.16
thioredoxin:protein disulfide reductase
|
–
|
|
|
BRENDA:
BS454734
|
|
|
|
8-vinyl-ADP + thioredoxin <=> 8-vinyl-2''-deoxy-ADP + thioredoxin_disulfide + H2O
|
1.17.4.1
ribonucleoside-diphosphate reductase
|
–
|
|
|
BRENDA:
BS376055
|
|
|
|
N-acetyl-L-methionine-(S)-S-oxide + thioredoxin <=> N-acetyl-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.13
L-methionine (S)-S-oxide reductase
|
–
–
|
|
|
BRENDA:
BS377211
|
|
|
|
N-acetyl-L-methionine_(R)-sulfoxide + thioredoxin <=> N-acetyl-L-methionine + thioredoxin_disulfide
|
1.8.4.11
peptide-methionine (S)-S-oxide reductase
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
–
|
|
|
BRENDA:
BS377208
|
|
|
|
H2O2 + reduced_glutaredoxin <=> H2O + thioredoxin_disulfide
|
1.11.1.25
glutaredoxin-dependent peroxiredoxin
|
–
|
|
|
BRENDA:
BS373386
|
|
|
|
thioredoxin_disulfide + NADH + H+ <=> thioredoxin + NAD+
|
1.8.1.9
thioredoxin-disulfide reductase
|
–
|
|
|
BRENDA:
BS398423
|
|
|
|
dabsyl-L-methionine_(R)-S-sulfoxide + dithiothreitol <=> dabsyl-L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS441262
|
|
|
|
tert-butyl_hydroperoxide + reduced_glutaredoxin <=> tert-butanol + thioredoxin_disulfide
|
1.11.1.25
glutaredoxin-dependent peroxiredoxin
|
–
|
|
|
BRENDA:
BS374699
|
|
|
|
5-Phosphoadenosine_3-phosphosulfate + thioredoxin <=> adenosine-3'',5''-bisphosphate + thioredoxin_disulfide + sulfite
|
1.8.4.8
phosphoadenylyl-sulfate reductase (thioredoxin)
|
–
|
|
|
BRENDA:
BS92823
|
|
|
|
3''-adenylyl-sulfate + thioredoxin <=> adenosine_3'',5''-bisphosphate + thioredoxin_disulfide + sulfite
|
1.8.4.8
phosphoadenylyl-sulfate reductase (thioredoxin)
|
–
|
|
|
BRENDA:
BS374986
|
|
|
|
cumene_hydroperoxide + reduced_glutaredoxin <=> 2-phenylpropan-2-ol + thioredoxin_disulfide
|
1.11.1.25
glutaredoxin-dependent peroxiredoxin
|
–
|
|
|
BRENDA:
BS372784
|
|
|
|
peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 thioredoxin <=> peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + thioredoxin_disulfide
|
1.8.98.2
sulfiredoxin
|
–
|
|
|
BRENDA:
BS415114
|
|
|
|
L-methionine_(R)-S-oxide + dithiothreitol <=> L-methionine + thioredoxin_disulfide + H2O
|
1.8.4.12
peptide-methionine (R)-S-oxide reductase
|
–
|
|
|
BRENDA:
BS385027
|
|
|
|
CMP + thioredoxin <=> dCMP + thioredoxin_disulfide + H2O
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
|
|
BRENDA:
BS287793
|
|