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Your translated search: pregnenolone = 39 reactions were found.
State Icon Reaction EC-Number Conf. maximal confidence score from EnzymeDetector PW
cholesterol + O2 + reduced_adrenodoxin + H+ <=> pregnenolone + 4-Methylpentanal + H2O + oxidized_ferredoxin 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
B
(20R,22R)-20,22-dihydroxy-cholesterol + O2 + reduced_adrenodoxin + H+ <=> pregnenolone + 4-Methylpentanal + oxidized_ferredoxin + H2O 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
MK
pregnenolone + NAD+ <=> 5-Pregnene-3,20-dione + NADH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
M
3''-phosphoadenylyl-sulfate + pregnenolone <=> adenosine_3,5''-bisphosphate + pregnenolone_sulfate + H+ 2.8.2.14 bile-salt sulfotransferase
2.8.2.15 steroid sulfotransferase
2.8.2.2 alcohol sulfotransferase
2.8.2.4 estrone sulfotransferase
–
–
–
–
K
pregnenolone + NAD+ <=> progesterone + NADH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
5.3.3.1 steroid Delta-isomerase
–
–
–
BK
pregnenolone_sulfate + H2O <=> pregnenolone + sulfate 3.1.6.2 steryl-sulfatase
–
K
pregnenolone + reduced_flavodoxin + O2 <=> 17alpha-hydroxypregnenolone + flavin + H2O 1.14.14.19 steroid 17alpha-monooxygenase
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
–
–
K
pregnenolone + UDP-glucose <=> UDP + pregnenolone_3-beta-D-glucoside 2.4.1.173 sterol 3beta-glucosyltransferase
2.4.1.192 nuatigenin 3beta-glucosyltransferase
–
–
pregnenolone + reduced_flavodoxin + O2 <=> 21-hydroxypregnenolone + flavin + H2O 1.14.14.16 steroid 21-monooxygenase
–
K
pregnenolone + NADPH + H+ + O2 <=> 7alpha-hydroxypregnenolone + NADP+ + H2O 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase
–
K
pregnenolone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 17alpha-hydroxypregnenolone + oxidized_[NADPH-hemoprotein_reductase] + H2O 1.14.14.19 steroid 17alpha-monooxygenase
–
M
pregnenolone + reduced_adrenodoxin + O2 <=> 7beta-hydroxy-pregnenolone + oxidized_ferredoxin + H2O 1.14.15.8 steroid 15beta-monooxygenase
–
pregnenolone + O2 <=> DELTA5-pregnen-3,20-dione + H2O2 1.1.3.6 cholesterol oxidase
–
pregnenolone + O2 <=> 5-Pregnene-3,20-dione + H2O2 1.1.3.6 cholesterol oxidase
–
DELTA5-pregnen-3,20-dione + O2 <=> pregnenolone + H2O2 1.1.3.6 cholesterol oxidase
–
pregnenolone + reduced_acceptor + O2 <=> 17alpha-hydroxypregnenolone + oxidized_acceptor + H2O 1.14.14.32 17alpha-hydroxyprogesterone deacetylase
–
pregnenolone + oleoyl-CoA <=> 20-oxopregn-5-en-3beta-yl_(9Z)-octadec-9-enoate + CoA 2.3.1.26 sterol O-acyltransferase
–
pregnenolone + reduced_acceptor + O2 <=> 17alpha-hydroxypregnenolone + A + H2O 1.14.14.19 steroid 17alpha-monooxygenase
1.14.14.32 17alpha-hydroxyprogesterone deacetylase
–
–
pregnenolone + NADH + O2 <=> 11-deoxycorticosterone + NAD+ + H2O 1.14.14.16 steroid 21-monooxygenase
–
pregnenolone + NADH + H+ <=> progesterone + NAD+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
pregnenolone + NAD+ <=> 5-Pregnene-3,20-dione + progesterone + NADH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
acyl-CoA + pregnenolone <=> CoA + pregnenolyl_3-O-acyl_ester 2.3.1.26 sterol O-acyltransferase
–
20alpha-hydroxycholesterol + reduced_adrenodoxin + O2 <=> pregnenolone + 4-Methylpentanal + oxidized_ferredoxin + H2O 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
cholesterol + 6 reduced_adrenodoxin_mutant_S112W + 3 O2 <=> pregnenolone + 4-Methylpentanal + 6 oxidized_adrenodoxin_mutant_S112W + 4 H2O 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
(22R)-22-hydroxycholesterol + reduced_adrenodoxin + O2 <=> pregnenolone + oxidized_ferredoxin + H2O 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
20alpha-hydroxycholesterol + reduced_adrenodoxin + O2 <=> pregnenolone + oxidized_ferredoxin + H2O 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
25-hydroxycholesterol + reduced_adrenodoxin + O2 <=> pregnenolone + oxidized_ferredoxin + H2O 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
cholesterol + reduced_ferredoxin + O2 <=> pregnenolone + adrenal_ferredoxin + H2O 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
25-hydroxycholesterol + O2 + reduced_ferredoxin <=> pregnenolone + H2O + Ferredoxin + 4-hydroxy-4-methylpentanal 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving)
–
pregnenolone <=> progesterone 5.3.3.1 steroid Delta-isomerase
–
pregnenolone + reduced_flavodoxin + O2 <=> dehydroepiandrosterone + acetate + flavin + H2O 1.14.14.32 17alpha-hydroxyprogesterone deacetylase
–
pregnenolone + NADPH <=> progesterone + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
pregnenolone + NADPH <=> 5-pregnene-3beta,20beta-diol + NADP+ 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
pregnenolone + NADPH + H+ <=> 5-Pregnene-3,20-dione + NADP+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
pregnenolone + NADP+ <=> progesterone + NADPH + H+ 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
pregnenolone + NADP+ <=> 5-Pregnene-3,20-dione + NADPH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
3beta,20alpha-Dihydroxypregn-5-ene + NADP+ <=> pregnenolone + NADPH 1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
3''-phosphoadenylylsulfate + pregnenolone <=> adenosine_3'',5''-bisphosphate + 5-pregnen-20-one_3-sulfate 2.8.2.15 steroid sulfotransferase
2.8.2.2 alcohol sulfotransferase
–
–
NADPH + O2 + pregnenolone <=> 17alpha-hydroxypregnenolone + NADP+ + H2O 1.14.14.19 steroid 17alpha-monooxygenase
–