|
|
kanamycin_A + ATP <=> kanamycin_3''-phosphate + ADP + H+
|
2.7.1.95
kanamycin kinase
2.7.1.B26
|
–
–
|
|
| |
BRENDA:
BR48067
KEGG:
R01888
MetaCyc:
KANAMYCIN-KINASE-RXN
SABIO-RK:
10956;
1947
|
|
|
|
kanamycin_A + NADP+ <=> 2''-dehydrokanamycin_A + NADPH + H+
|
1.1.1.355
2'-dehydrokanamycin reductase
|
–
|
MK
|
| |
BRENDA:
BR50592
KEGG:
R10417
MetaCyc:
RXN-14402
|
|
|
|
2''-deamino-2''-hydroxyneamine + UDP-alpha-D-kanosamine <=> kanamycin_A + UDP + H+
|
2.4.1.301
2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
|
–
|
MK
|
| |
BRENDA:
BR50647
KEGG:
R10424
MetaCyc:
RXN-13125
|
|
|
|
kanamycin_A + O-carbamoyladenylate <=> 6''''-O-carbamoylkanamycin_A + AMP + H+
|
6.1.2.2
nebramycin 5' synthase
|
–
|
|
| |
BRENDA:
BR50757
KEGG:
R10544
MetaCyc:
RXN-13167
|
|
|
|
Carbamoyl_phosphate + kanamycin_A + ATP + H2O <=> 6''''-O-carbamoylkanamycin_A + AMP + diphosphate + phosphate + H+
|
6.1.2.2
nebramycin 5' synthase
|
–
|
K
|
| |
BRENDA:
BR51040
KEGG:
R10768
MetaCyc:
RXN-15285
|
|
|
|
GTP + kanamycin_A <=> kanamycin_A_2''''-phosphate + GDP + H+
|
2.7.1.190
aminoglycoside 2''-phosphotransferase
|
–
|
|
| |
BRENDA:
BS433788
MetaCyc:
RXN-16730
|
|
|
|
acetyl-CoA + kanamycin_A <=> CoA + N6''-acetylkanamycin_A
|
2.3.1.82
aminoglycoside 6'-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS353871
SABIO-RK:
11223
|
|
|
|
kanamycin_A + 2-oxoglutarate <=> 6''-Oxokanamycin_X + L-glutamate
|
2.6.1.94
2'-deamino-2'-hydroxyneamine transaminase
|
–
|
K
|
| |
KEGG:
R11269
|
|
|
|
butyryl-CoA + kanamycin_A <=> CoA + N3''-butyryl-kanamycin_A
|
2.3.1.81
aminoglycoside 3-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS408798
|
|
|
|
acetyl-CoA + kanamycin_A <=> CoA + N6''-acetylkanamycin
|
2.3.1.82
aminoglycoside 6'-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS353869
|
|
|
|
acetyl-CoA + kanamycin_A <=> CoA + N3''-acetylkanamycin
|
2.3.1.81
aminoglycoside 3-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS321390
|
|
|
|
acetyl-CoA + kanamycin_A <=> CoA + N3''-acetylkanamycin_A
|
2.3.1.81
aminoglycoside 3-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS354277
|
|
|
|
acetyl-CoA + kanamycin_A <=> CoA + N3-acetylkanamycin
|
2.3.1.60
gentamicin 3-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS455187
|
|
|
|
propionyl-CoA + kanamycin_A <=> CoA + N6''-propionylkanamycin_A
|
2.3.1.82
aminoglycoside 6'-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS453928
|
|
|
|
propionyl-CoA + kanamycin_A <=> CoA + N3''-propionyl-kanamycin_A
|
2.3.1.81
aminoglycoside 3-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS409947
|
|
|
|
GTP + kanamycin_A <=> GDP + kanamycin_A_3''-phosphate
|
2.7.1.B26
|
–
|
|
| |
BRENDA:
BS433789
|
|
|
|
glycyl-CoA + kanamycin_A <=> CoA + N3''-glycyl-kanamycin_A
|
2.3.1.81
aminoglycoside 3-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS409549
|
|
|
|
ATP + kanamycin_A <=> diphosphate + 2''''-adenylylkanamycin_A
|
2.7.7.46
gentamicin 2''-nucleotidyltransferase
|
–
|
|
| |
BRENDA:
BS359900
|
|
|
|
malonyl-CoA + kanamycin_A <=> CoA + N3''-malonylkanamycin_A
|
2.3.1.81
aminoglycoside 3-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS420920
|
|
|
|
propionyl-CoA + kanamycin_A <=> N6''-propionylkanamycin_A
|
2.3.1.82
aminoglycoside 6'-N-acetyltransferase
|
–
|
|
| |
BRENDA:
BS451967
|
|
|
|
ATP + H2O + kanamycin_A <=> ADP + phosphate + kanamycin_A
|
7.6.2.2
ABC-type xenobiotic transporter
|
–
|
|
| |
BRENDA:
BS445049
|
|
|
|
ATP + kanamycin_A <=> ADP + kanamycin_A_2''''-phosphate
|
2.7.1.190
aminoglycoside 2''-phosphotransferase
|
–
|
|
| |
BRENDA:
BS433484
|
|
