MMTB

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EnzymeDetector confidence threshold:

Your translated search: isocitrate = 16 reactions were found.

	Reaction	EC-Number	Conf. maximal confidence score from EnzymeDetector	PW
	isocitrate <=> (1S,2S)-1-hydroxypropane-1,2,3-tricarboxylate	5.1.2.6 isocitrate epimerase	–
BRENDA: BR183 KEGG: R02318 MetaCyc: ISOCITRATE-EPIMERASE-RXN
	isocitrate + NAD+ <=> 2-oxoglutarate + CO2 + NADH	1.1.1.286 isocitrate---homoisocitrate dehydrogenase 1.1.1.41 isocitrate dehydrogenase (NAD+) 1.1.1.42 isocitrate dehydrogenase (NADP+) 1.1.1.87 homoisocitrate dehydrogenase	– – – –	BMK
BRENDA: BR29304; BS371189 KEGG: R00709 MetaCyc: ISOCITRATE-DEHYDROGENASE-NAD+-RXN SABIO-RK: 15068; 270		citric acid cycle TCA cycle II (plants and fungi) TCA cycle III (animals) L-glutamine biosynthesis III Metabolic pathways Microbial metabolism in diverse environments Biosynthesis of secondary metabolites Carbon metabolism Citrate cycle (TCA cycle) Biosynthesis of amino acids 2-Oxocarboxylic acid metabolism
	isocitrate + NADP+ <=> 2-oxoglutarate + CO2 + NADPH	1.1.1.286 isocitrate---homoisocitrate dehydrogenase 1.1.1.41 isocitrate dehydrogenase (NAD+) 1.1.1.42 isocitrate dehydrogenase (NADP+)	– – –	BMK
BRENDA: BR29305; BS370920 KEGG: R00267 MetaCyc: ISOCITDEH-RXN SABIO-RK: 14842; 15247; 269		methylaspartate cycle citric acid cycle TCA cycle VI (Helicobacter) TCA cycle V (2-oxoglutarate synthase) TCA cycle IV (2-oxoglutarate decarboxylase) TCA cycle I (prokaryotic) TCA cycle VII (acetate-producers) partial TCA cycle (obligate autotrophs) L-glutamine biosynthesis III reductive TCA cycle I cytosolic NADPH production (yeast) methylaspartate cycle mixed acid fermentation ethene biosynthesis V (engineered) Metabolic pathways Microbial metabolism in diverse environments Carbon metabolism Biosynthesis of amino acids Glutathione metabolism Carbon fixation pathways in prokaryotes 2-Oxocarboxylic acid metabolism
	isocitrate <=> glyoxylate + succinate	4.1.3.1 isocitrate lyase	–	BMK
BRENDA: BR3364; BS380792 KEGG: R00479 MetaCyc: ISOCIT-CLEAV-RXN SABIO-RK: 14841		citric acid cycle glyoxylate cycle Metabolic pathways Microbial metabolism in diverse environments Glyoxylate and dicarboxylate metabolism Biosynthesis of secondary metabolites Carbon metabolism
	caffeoyl-CoA + isocitrate <=> 2-caffeoylisocitric_acid + CoA	2.3.1.126 isocitrate O-dihydroxycinnamoyltransferase	–
BRENDA: BR43987 KEGG: R01946 MetaCyc: 2.3.1.126-RXN
	citrate <=> isocitrate	4.2.1.3 aconitate hydratase	–	K
BRENDA: BS18704 KEGG: R01324 MetaCyc: RXN-14047 SABIO-RK: 272		Metabolic pathways Carbon metabolism Biosynthesis of amino acids 2-Oxocarboxylic acid metabolism
	cis-aconitate + H2O <=> isocitrate	4.2.1.3 aconitate hydratase	–	MK
BRENDA: BS18708 KEGG: R01900 MetaCyc: ACONITATEHYDR-RXN SABIO-RK: 273		TCA cycle VI (Helicobacter) TCA cycle V (2-oxoglutarate synthase) TCA cycle IV (2-oxoglutarate decarboxylase) TCA cycle I (prokaryotic) TCA cycle VII (acetate-producers) TCA cycle II (plants and fungi) TCA cycle III (animals) partial TCA cycle (obligate autotrophs) L-glutamine biosynthesis III reductive TCA cycle II reductive TCA cycle I glyoxylate cycle methylaspartate cycle mixed acid fermentation ethene biosynthesis V (engineered) Metabolic pathways Microbial metabolism in diverse environments Glyoxylate and dicarboxylate metabolism Biosynthesis of secondary metabolites Citrate cycle (TCA cycle) Carbon fixation pathways in prokaryotes 2-Oxocarboxylic acid metabolism
	isocitrate + NADP+ <=> oxalosuccinate + NADPH + H+	1.1.1.42 isocitrate dehydrogenase (NADP+)	–	K
BRENDA: BS438365 KEGG: R01899 MetaCyc: RXN-9951 SABIO-RK: 242		Metabolic pathways Microbial metabolism in diverse environments Biosynthesis of secondary metabolites Citrate cycle (TCA cycle) 2-Oxocarboxylic acid metabolism
	isocitrate + NAD+ <=> oxalosuccinate + NADH + H+	1.1.1	–	M
MetaCyc: R23-RXN		reductive TCA cycle II
	sinapoyl-CoA + isocitrate <=> CoA + sinapoylisocitric_acid	2.3.1.126 isocitrate O-dihydroxycinnamoyltransferase	–
BRENDA: BS320399
	feruloyl-CoA + isocitrate <=> CoA + feruloylisocitric_acid	2.3.1.126 isocitrate O-dihydroxycinnamoyltransferase	–
BRENDA: BS320398
	4-coumaroyl-CoA + isocitrate <=> CoA + 4-coumaroylisocitrate	2.3.1.126 isocitrate O-dihydroxycinnamoyltransferase	–
BRENDA: BS451928
	8-(4-bromo-2,3-dioxobutylthio)-NAD+ + isocitrate <=> 2-oxoglutarate + CO2 + 8-(4-bromo-2,3-dioxobutylthio)-NADH	1.1.1.41 isocitrate dehydrogenase (NAD+)	–
BRENDA: BS188123
	isocitrate + NAD+ <=> 2-oxoglutarate + NADH + H+	1.1.1.42 isocitrate dehydrogenase (NADP+)	–
BRENDA: BS439626
	isocitrate + NADP+ <=> 2-oxoglutarate + NADPH + H+	1.1.1.42 isocitrate dehydrogenase (NADP+)	–
BRENDA: BS438364
	ATP + isocitrate + CoA <=> ADP + phosphate + isocitryl-CoA	6.2.1.9 malate---CoA ligase	–
BRENDA: BS356