|
|
H2O + formyl-CoA <=> H+ + formate + CoA
|
3.1.2.10
formyl-CoA hydrolase
|
–
|
MK
|
|
BRENDA:
BR10670
KEGG:
R00521
MetaCyc:
FORMYL-COA-HYDROLASE-RXN
|
|
|
|
S-formylglutathione + H2O <=> H+ + formate + glutathione
|
3.1.1.56
methylumbelliferyl-acetate deacetylase
3.1.2.12
S-formylglutathione hydrolase
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
–
–
|
BMK
|
|
BRENDA:
BR10672
KEGG:
R00527
MetaCyc:
S-FORMYLGLUTATHIONE-HYDROLASE-RXN
SABIO-RK:
945
|
|
|
|
7,8-dihydrofolate + formate + ATP <=> N10-formyltetrahydropteroylglutamate + phosphate + ADP
|
6.3.4.17
formate---dihydrofolate ligase
|
–
|
|
|
BRENDA:
BR138
KEGG:
R02238
MetaCyc:
FORMATE--DIHYDROFOLATE-LIGASE-RXN
|
|
|
|
Formamide + H2O <=> formate + NH3
|
3.5.1.49
formamidase
3.5.1.56
N,N-dimethylformamidase
|
–
–
|
MK
|
|
BRENDA:
BR22693
KEGG:
R00524
MetaCyc:
FORMAMIDASE-RXN
|
|
|
|
H2O + dimethylformamide <=> Dimethylamine + formate
|
3.5.1.56
N,N-dimethylformamidase
|
–
|
K
|
|
BRENDA:
BR22700
KEGG:
R02509
MetaCyc:
NN-DIMETHYLFORMAMIDASE-RXN
|
|
|
|
N-formyl-L-glutamate + H2O <=> L-glutamate + formate
|
3.5.1.68
N-formylglutamate deformylase
3.5.1.8
formylaspartate deformylase
|
–
–
|
BMK
|
|
BRENDA:
BR22707
KEGG:
R00525
MetaCyc:
N-FORMYLGLUTAMATE-DEFORMYLASE-RXN
|
|
|
|
H2O + N-formyl-L-aspartate <=> L-aspartate + formate
|
3.5.1.15
aspartoacylase
3.5.1.8
formylaspartate deformylase
|
–
–
|
BK
|
|
BRENDA:
BR22713
KEGG:
R00526
MetaCyc:
FORMYLASPARTATE-DEFORMYLASE-RXN
|
|
|
|
N-formyl-L-kynurenine + H2O <=> L-kynurenine + formate + H+
|
3.5.1.9
arylformamidase
|
–
|
BMK
|
|
BRENDA:
BR22715
KEGG:
R01959
MetaCyc:
ARYLFORMAMIDASE-RXN
SABIO-RK:
2006
|
|
|
|
GTP + H2O <=> H+ + formate + 7,8-dihydroneopterin_3''-triphosphate
|
3.5.4.16
GTP cyclohydrolase I
|
–
|
BMK
|
|
BRENDA:
BR22737
KEGG:
R00424
MetaCyc:
GTP-CYCLOHYDRO-I-RXN
SABIO-RK:
9177
|
|
|
|
H2O + GTP <=> H+ + diphosphate + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate + formate
|
3.5.4.25
GTP cyclohydrolase II
|
–
|
BMK
|
|
BRENDA:
BR26117
KEGG:
R00425
MetaCyc:
GTP-CYCLOHYDRO-II-RXN
SABIO-RK:
880
|
|
|
|
oxalate + H+ <=> formate + CO2
|
4.1.1.2
oxalate decarboxylase
|
–
|
MK
|
|
BRENDA:
BR280
KEGG:
R00522
MetaCyc:
OXALATE-DECARBOXYLASE-RXN
SABIO-RK:
941
|
|
|
|
formate + NAD+ <=> CO2 + NADH
|
1.17.1.10
formate dehydrogenase (NADP+)
1.17.1.9
formate dehydrogenase
|
–
–
|
BMK
|
|
BRENDA:
BR29391
KEGG:
R00519
MetaCyc:
1.2.1.2-RXN
SABIO-RK:
939
|
|
|
|
formate + NADP+ <=> CO2 + NADPH
|
1.17.1.10
formate dehydrogenase (NADP+)
1.17.1.9
formate dehydrogenase
|
–
–
|
BMK
|
|
BRENDA:
BR29403
KEGG:
R00134
MetaCyc:
FORMATE-DEHYDROGENASE-NADP+-RXN
|
|
|
|
formaldehyde + NAD+ + H2O <=> formate + NADH + H+
|
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.21
glycolaldehyde dehydrogenase
1.2.1.22
lactaldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.32
aminomuconate-semialdehyde dehydrogenase
1.2.1.46
formaldehyde dehydrogenase
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.65
salicylaldehyde dehydrogenase
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
|
–
–
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR29406
KEGG:
R00604
MetaCyc:
FORMALDEHYDE-DEHYDROGENASE-RXN
SABIO-RK:
996
|
|
|
|
ferricytochrome_b5 + formate <=> ferricytochrome_b5 + CO2 + H+
|
1.17.2.3
formate dehydrogenase (cytochrome-c-553)
1.2.2.1
formate dehydrogenase (cytochrome)
|
–
–
|
|
|
BRENDA:
BR29427
KEGG:
R03215
MetaCyc:
1.2.2.3-RXN
|
|
|
|
formaldehyde + H2O <=> methanol + formate + H+
|
1.2.98.1
formaldehyde dismutase
|
–
|
K
|
|
BRENDA:
BR36794
KEGG:
R00614
MetaCyc:
RXN-11453
|
|
|
|
H2O + N-formyl-L-methionine <=> L-methionine + formate
|
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.16
acetylornithine deacetylase
3.5.1.31
formylmethionine deformylase
3.5.1.87
N-carbamoyl-L-amino-acid hydrolase
3.5.1.88
peptide deformylase
|
–
–
–
–
–
|
K
|
|
BRENDA:
BR36959
KEGG:
R00653
MetaCyc:
FORMYLMETHIONINE-DEFORMYLASE-RXN
SABIO-RK:
329
|
|
|
|
[protein]_N-terminal-formyl-L-methionine + H2O <=> N-terminal_L-methionyl-[protein] + formate
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BR36960
KEGG:
R05635
MetaCyc:
3.5.1.88-RXN
SABIO-RK:
5233
|
|
|
|
O2 + 2,4''-dihydroxyacetophenone <=> H+ + formate + 4-hydroxybenzoate
|
1.13.11.41
2,4'-dihydroxyacetophenone dioxygenase
|
–
|
K
|
|
BRENDA:
BR40470
KEGG:
R01305
MetaCyc:
1.13.11.41-RXN
|
|
|
|
O2 + Latia_luciferin + reduced_acceptor <=> 4-(2,6,6-trimethylcyclohex-1-en-1-yl)butan-2-one + formate + CO2 + H2O + acceptor + H+ + light
|
1.14.99.21
Latia-luciferin monooxygenase (demethylating)
|
–
|
|
|
BRENDA:
BR40517;
BS442456
KEGG:
R03907
MetaCyc:
1.14.99.21-RXN
|
|
|
|
formate + acetyl-CoA <=> pyruvate + CoA
|
2.3.1.54
formate C-acetyltransferase
|
–
|
BMK
|
|
BRENDA:
BR44056
KEGG:
R00212
MetaCyc:
PYRUVFORMLY-RXN
SABIO-RK:
146
|
|
|
|
formate + ATP <=> formyl_phosphate + ADP
|
2.7.2.6
formate kinase
6.3.4.3
formate---tetrahydrofolate ligase
|
–
–
|
K
|
|
BRENDA:
BR47828
KEGG:
R00518
MetaCyc:
FORMATE-KINASE-RXN
|
|
|
|
formyl-CoA + oxalate <=> formate + oxalyl-CoA
|
2.8.3.16
formyl-CoA transferase
|
–
|
M
|
|
BRENDA:
BR48127
KEGG:
R07290
MetaCyc:
RXN0-1382
|
|
|
|
L-lactate <=> formate + acetaldehyde
|
4.1.2.36
lactate aldolase
|
–
|
K
|
|
BRENDA:
BR48322
KEGG:
R00753
MetaCyc:
LACTATE-ALDOLASE-RXN
|
|
|
|
octadecanal + O2 + NADPH + H+ <=> heptadecane + formate + H2O + NADP+
|
4.1.99.5
aldehyde oxygenase (deformylating)
|
–
|
M
|
|
BRENDA:
BR48325
KEGG:
R03728
MetaCyc:
OCTADECANAL-DECARBONYLASE-RXN
|
|
|
|
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 <=> H+ + 3-(methylthio)propanoate + formate + CO
|
1.13.11.53
acireductone dioxygenase (Ni2+-requiring)
1.13.11.54
acireductone dioxygenase [iron(II)-requiring]
|
–
–
|
MK
|
|
BRENDA:
BR48659
KEGG:
R07363
MetaCyc:
R146-RXN
|
|
|
|
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 <=> H+ + 4-methylsulfanyl-2-oxobutanoate + formate
|
1.13.11.54
acireductone dioxygenase [iron(II)-requiring]
|
–
|
BMK
|
|
BRENDA:
BR48660
KEGG:
R07364
MetaCyc:
R147-RXN
|
|
|
|
N-benzylformamide + H2O <=> formate + benzylamine
|
3.5.1.91
N-substituted formamide deformylase
|
–
|
|
|
BRENDA:
BR48714
KEGG:
R07303
MetaCyc:
3.5.1.91-RXN
SABIO-RK:
8363
|
|
|
|
D-ribulose_5-phosphate <=> H+ + formate + L-3,4-dihydroxybutan-2-one_4-phosphate
|
4.1.99.12
3,4-dihydroxy-2-butanone-4-phosphate synthase
|
–
|
BMK
|
|
BRENDA:
BR48836
KEGG:
R07281
MetaCyc:
DIOHBUTANONEPSYN-RXN
SABIO-RK:
9052
|
|
|
|
N-formylmaleamic_acid + H2O <=> H+ + Maleamate + formate
|
3.5.1.106
N-formylmaleamate deformylase
|
–
|
MK
|
|
BRENDA:
BR49200
KEGG:
R09126
MetaCyc:
RXN-11318
|
|
|
|
2-amino-5-formylamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H2O <=> H+ + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate + formate
|
3.5.1.102
2-amino-5-formylamino-6-ribosylaminopyrimidin-4(3H)-one 5'-monophosphate deformylase
|
–
|
BMK
|
|
BRENDA:
BR49204
KEGG:
R09374
MetaCyc:
RXN-10056
|
|
|
|
2,3-epoxy-2,3-dihydrobenzoyl-CoA + H2O <=> cis-3,4-dehydroadipyl-CoA_semialdehyde + formate + H+
|
4.1.2.44
2,3-epoxybenzoyl-CoA dihydrolase
|
–
|
MK
|
|
BRENDA:
BR49206
KEGG:
R09556
MetaCyc:
RXN-11054
|
|
|
|
S-adenosyl-L-methionine + 5-amino-1-(5-phospho-D-ribosyl)imidazole <=> 2-methyl-4-amino-5-hydroxymethylpyrimidine_phosphate + 5''-deoxyadenosine + L-methionine + formate + CO + H+
|
4.1.99.17
phosphomethylpyrimidine synthase
|
–
|
BMK
|
|
BRENDA:
BR49773
KEGG:
R03472
MetaCyc:
PYRIMSYN1-RXN
|
|
|
|
2-hydroxyethylphosphonate + O2 <=> H+ + hydroxymethylphosphonate + formate
|
1.13.11.72
2-hydroxyethylphosphonate dioxygenase
|
–
|
MK
|
|
BRENDA:
BR50255
KEGG:
R08864
MetaCyc:
RXN-10824
|
|
|
|
GTP + H2O <=> 7,8-dihydroneopterin_2,3''-cyclic_phosphate + formate + diphosphate + H+
|
3.5.4.16
GTP cyclohydrolase I
3.5.4.39
GTP cyclohydrolase IV
|
–
–
|
BMK
|
|
BRENDA:
BR50468
KEGG:
R10348
MetaCyc:
RXN-10063
|
|
|
|
formaldehyde + H2O + oxidized_ferredoxin <=> formate + H+ + reduced_ferredoxin_[iron-sulfur]_cluster
|
1.2.7.5
aldehyde ferredoxin oxidoreductase
1.2.7.B2
|
–
–
|
|
|
BRENDA:
BR50606
MetaCyc:
RXN-21602
|
|
|
|
5-aminoimidazole-4-carboxamide_ribonucleotide + formate + ATP <=> 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide + ADP + phosphate
|
6.3.4.23
formate---phosphoribosylaminoimidazolecarboxamide ligase
|
–
|
BMK
|
|
BRENDA:
BR50732
KEGG:
R06975
MetaCyc:
RXN-10066
|
|
|
|
formate + coenzyme_F420 + H+ <=> CO2 + reduced_coenzyme_F420
|
1.17.1.9
formate dehydrogenase
1.17.98.3
formate dehydrogenase (coenzyme F420)
|
–
–
|
BK
|
|
BRENDA:
BR51102
KEGG:
R10797
MetaCyc:
RXN-15617
SABIO-RK:
11358;
11359
|
|
|
|
formate + NAD+ + oxidized_ferredoxin <=> CO2 + NADH + H+ + reduced_ferredoxin_[iron-sulfur]_cluster
|
1.17.1.11
formate dehydrogenase (NAD+, ferredoxin)
|
–
|
|
|
BRENDA:
BR51442
KEGG:
R11818
MetaCyc:
RXN-16835
|
|
|
|
7,8-dihydroneopterin + O2 <=> dihydroxanthopterin + formate + glycolaldehyde + H+
|
1.13.11.81
7,8-dihydroneopterin oxygenase
|
–
|
K
|
|
BRENDA:
BR51490
KEGG:
R11037
MetaCyc:
RXN-16480
|
|
|
|
NADPH + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + CO2 <=> NADP+ + oxidized_ferredoxin + formate
|
1.17.1.M4
1.2.1.B29
|
–
–
|
|
|
BRENDA:
BR51551
MetaCyc:
RXN-21796
|
|
|
|
coenzyme_B + coenzyme_M + reduced_ferredoxin_[iron-sulfur]_cluster + CO2 <=> CoM-S-S-CoB + formate + oxidized_ferredoxin
|
1.8.98.6
formate:CoB-CoM heterodisulfide,ferredoxin reductase
|
–
|
BMK
|
|
BRENDA:
BR52242
KEGG:
R11944
MetaCyc:
RXN-18529
|
|
|
|
a_14alpha-methylsteroid + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> a_DELTA14-steroid + formate + H2O + oxidized_ferredoxin
|
1.14.15.36
sterol 14alpha-demethylase (ferredoxin)
|
–
|
|
|
BRENDA:
BR52674
KEGG:
R12317
MetaCyc:
RXN-20136
|
|
|
|
a_14alpha-formylsteroid + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> a_DELTA14-steroid + formate + H2O + oxidized_ferredoxin
|
1.14.15.36
sterol 14alpha-demethylase (ferredoxin)
|
–
|
|
|
BRENDA:
BR52677
KEGG:
R12322
MetaCyc:
RXN-20135
|
|
|
|
hydroxymethylphosphonate + O2 <=> formate + phosphate + H+
|
1.13.11.72
2-hydroxyethylphosphonate dioxygenase
1.13.11.89
(hydroxymethyl)phosphonate dioxygenase
|
–
–
|
MK
|
|
BRENDA:
BR52781
KEGG:
R12451
MetaCyc:
RXN-20741
|
|
|
|
formyl-isoglutamine + H2O <=> L-isoglutamine + formate
|
0.0.0.0
|
–
|
BM
|
|
BRENDA:
BR52886
MetaCyc:
RXN-7592
|
|
|
|
2-oxobutyrate + CoA <=> propionyl-CoA + formate
|
2.3.1
2.3.1.54
formate C-acetyltransferase
|
–
–
|
BMK
|
|
BRENDA:
BS321064
KEGG:
R06987
MetaCyc:
KETOBUTFORMLY-RXN
|
|
|
|
N-butylformamide + H2O <=> formate + n-butylamine
|
3.5.1.91
N-substituted formamide deformylase
|
–
|
|
|
BRENDA:
BS377237
MetaCyc:
RXN-21418
SABIO-RK:
8364
|
|
|
|
H+ + formate <=> CO2 + H2
|
1.12.99.6
hydrogenase (acceptor)
|
–
|
M
|
|
BRENDA:
BS397400
MetaCyc:
FHLMULTI-RXN
|
|
|
|
menaquinone + H+ + formate <=> menaquinol + CO2 + H+
|
1.17.5.3
formate dehydrogenase-N
|
–
|
M
|
|
BRENDA:
BS402645
MetaCyc:
FORMATEDEHYDROG-RXN
|
|
|
|
formyl-CoA + succinate <=> formate + succinyl-CoA
|
2.8.3.16
formyl-CoA transferase
2.8.3.18
succinyl-CoA:acetate CoA-transferase
|
–
–
|
|
|
BRENDA:
BS428949
MetaCyc:
RXN-19490
|
|
|
|
formate + ATP + H+ <=> CO2 + dATP + H2O
|
1.1.98.6
ribonucleoside-triphosphate reductase (formate)
|
–
|
MK
|
|
BRENDA:
BS439175
KEGG:
R11634
MetaCyc:
RXN0-745
|
|
|
|
formate + CTP + H+ <=> dCTP + CO2 + H2O
|
1.1.98.6
ribonucleoside-triphosphate reductase (formate)
|
–
|
BMK
|
|
BRENDA:
BS439364
KEGG:
R11636
MetaCyc:
RXN0-723
|
|
|
|
formate + GTP + H+ <=> dGTP + CO2 + H2O
|
1.1.98.6
ribonucleoside-triphosphate reductase (formate)
|
–
|
MK
|
|
BRENDA:
BS439595
KEGG:
R11633
MetaCyc:
RXN0-746
|
|
|
|
formate + UTP + H+ <=> dUTP + CO2 + H2O
|
1.1.98.6
ribonucleoside-triphosphate reductase (formate)
|
–
|
BMK
|
|
BRENDA:
BS439976
KEGG:
R11635
MetaCyc:
RXN0-724
|
|
|
|
tetrahydrofolate + ATP + formate <=> 10-formyltetrahydrofolate + ADP + phosphate
|
6.3.4.3
formate---tetrahydrofolate ligase
|
–
|
BMK
|
|
BRENDA:
BR140;
BS443140
KEGG:
R00943
MetaCyc:
FORMATETHFLIG-RXN
SABIO-RK:
51
|
|
|
|
beta-glycinamide_ribonucleotide + formate + ATP <=> H+ + formylglycinamide_ribonucleotide + ADP + phosphate
|
2.1.2
2.1.2.B3
6.3.1.i
|
–
–
–
|
M
|
|
BRENDA:
BS454340
KEGG:
R06974
MetaCyc:
GARTRANSFORMYL2-RXN
|
|
|
|
10-formyltetrahydrofolate + H2O <=> tetrahydrofolate + formate + H+
|
3.5.1.10
formyltetrahydrofolate deformylase
|
–
|
BMK
|
|
BRENDA:
BR22680
KEGG:
R00944
MetaCyc:
FORMYLTHFDEFORMYL-RXN
SABIO-RK:
1259
|
|
|
|
2-hydroxymuconate-6-semialdehyde + H2O <=> formate + 2-oxopent-4-enoate
|
3.7.1.9
2-hydroxymuconate-6-semialdehyde hydrolase
|
–
|
BK
|
|
BRENDA:
BR26140
KEGG:
R02604
|
|
|
|
a_14alpha-methylsteroid + 3 reduced_flavodoxin + 3 O2 <=> a_DELTA14-steroid + formate + 3 flavin + 4 H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BR29146
KEGG:
R12118
|
|
|
|
formate + a_quinone <=> CO2 + a_quinol
|
1.17.5.3
formate dehydrogenase-N
|
–
|
|
|
BRENDA:
BR49157
KEGG:
R09494
|
|
|
|
formate + acceptor <=> CO2 + reduced_acceptor
|
1.17.99.7
formate dehydrogenase (acceptor)
|
–
|
B
|
|
BRENDA:
BR49158
KEGG:
R09481
|
|
|
|
testosterone + 3 O2 + 3 reduced_flavodoxin <=> 17beta-estradiol + formate + 4 H2O + 3 flavin
|
1.14.14.14
aromatase
|
–
|
|
|
BRENDA:
BR50742
KEGG:
R10511
|
|
|
|
19-oxotestosterone + O2 + reduced_flavodoxin <=> 17beta-estradiol + formate + H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50745
KEGG:
R03087
|
|
|
|
4-androstene-3,17-dione + 3 O2 + 3 reduced_flavodoxin <=> estrone + formate + 4 H2O + 3 flavin
|
1.14.14.14
aromatase
|
–
|
|
|
BRENDA:
BR50746
KEGG:
R10515
|
|
|
|
19-oxoandrost-4-ene-3,17-dione + O2 + reduced_flavodoxin <=> estrone + formate + H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50749;
BS425316
KEGG:
R02351
|
|
|
|
formate + NTP + H+ <=> 2''-deoxyribonucleoside_5''-triphosphate + CO2 + H2O
|
1.1.98.6
ribonucleoside-triphosphate reductase (formate)
|
–
|
|
|
BRENDA:
BR51922
KEGG:
R11592
MetaCyc:
RIBONUCLEOSIDE-TRIP-REDUCT-RXN
|
|
|
|
a_14alpha-formylsteroid + reduced_flavodoxin + O2 <=> a_DELTA14-steroid + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BR52437
KEGG:
R12121
|
|
|
|
4,5-dihydro-4-oxo-5-imidazolepropanoate + H2O <=> 4-oxoglutaramate + formate + NH3
|
0.0.0.0
|
–
|
BK
|
|
BRENDA:
BR52885
KEGG:
R04283
|
|
|
|
N-formylanthranilic_acid + H2O <=> formate + anthranilate
|
3.5.1.9
arylformamidase
|
–
|
K
|
|
BRENDA:
BS140693
KEGG:
R00988
|
|
|
|
obtusifoliol + reduced_flavodoxin + O2 <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
K
|
|
BRENDA:
BS186733
KEGG:
R05731
|
|
|
|
lanosterol + reduced_flavodoxin + O2 <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
BK
|
|
BRENDA:
BS186735
KEGG:
R05640
|
|
|
|
2,5-dihydroxypyridine + O2 + H2O <=> Maleamate + formate
|
1.13.11.9
2,5-dihydroxypyridine 5,6-dioxygenase
|
–
|
|
|
BRENDA:
BS261072
KEGG:
R03204
|
|
|
|
H2O + N-formyl-L-methionylaminoacyl-tRNA <=> L-methionylaminoacyl-tRNA + formate + H+
|
3.5.1.88
peptide deformylase
|
–
|
|
|
KEGG:
R04268
MetaCyc:
3.5.1.27-RXN
|
|
|
|
ferricytochrome_b5 + formate <=> ferricytochrome_b5 + CO2 + H+
|
1.2.2.1
formate dehydrogenase (cytochrome)
|
–
|
K
|
|
KEGG:
R03146
MetaCyc:
FORMATE-DEHYDROGENASE-CYTOCHROME-RXN
|
|
|
|
N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-amino-5-aminomethyl-2-methylpyrimidine + formate
|
3.5.1
|
–
|
MK
|
|
KEGG:
R11313
MetaCyc:
RXN-12612
|
|
|
|
N-Formyldemecolcine + H2O <=> colcemid + formate
|
3.5.1
|
–
|
MK
|
|
KEGG:
R08451
MetaCyc:
RXN-13557
|
|
|
|
formylmethanofuran + H2O <=> methanofuran + formate
|
1.2.7.12
formylmethanofuran dehydrogenase
|
–
|
K
|
|
KEGG:
R08060
MetaCyc:
RXN-14028
|
|
|
|
S-adenosyl-L-methionine + 5-amino-1-(5-phospho-D-ribosyl)imidazole + reduced_acceptor <=> 5-hydroxybenzimidazole + phosphate + NH3 + formate + 5''-deoxyadenosine + L-methionine + H+ + acceptor
|
4.1.99.23
5-hydroxybenzimidazole synthase
|
–
|
M
|
|
KEGG:
R11919
MetaCyc:
RXN-17122
|
|
|
|
lanosterol + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + oxidized_ferredoxin + H2O
|
1.14.15.36
sterol 14alpha-demethylase (ferredoxin)
|
–
|
K
|
|
KEGG:
R12323
MetaCyc:
RXN-20130
|
|
|
|
2,6-dihydroxynicotinate + O2 + H2O <=> H+ + Maleamate + formate + CO2
|
not assigned
|
–
|
MK
|
|
KEGG:
R07983
MetaCyc:
RXN-7586
|
|
|
|
4-deoxy-4-formamido-alpha-L-arabinopyranosyl_ditrans,octacis-undecaprenyl_phosphate + H2O <=> 4-amino-4-deoxy-alpha-L-arabinopyranosyl_undecaprenyl_phosphate + formate
|
3.5.1
|
–
|
MK
|
|
KEGG:
R07662
MetaCyc:
RXN0-5409
|
|
|
|
formaldehyde + NADP+ + H2O <=> formate + NADPH + H+
|
1.2.1.4
aldehyde dehydrogenase (NADP+)
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.77
3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.8
betaine-aldehyde dehydrogenase
|
–
–
–
–
|
|
|
BRENDA:
BS231680
SABIO-RK:
14360
|
|
|
|
N-formyl-Met-Leu-p-nitroanilide + H2O <=> formate + Met-Leu-p-nitroanilide
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259951
SABIO-RK:
12285
|
|
|
|
N-formyl-Met-Ala-Ser + H2O <=> formate + Met-Ala-Ser
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259968;
BS373217
SABIO-RK:
13546
|
|
|
|
N-formyl-Nle-Ala-Ser + H2O <=> formate + L-Nle-L-Ala-L-Ser
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259969
SABIO-RK:
13363
|
|
|
|
N-formyl-Nva-Ala-Ser + H2O <=> formate + Nva-Ala-Ser
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259970
SABIO-RK:
13364
|
|
|
|
N-formyl-Phe-Ala-Ser + H2O <=> formate + Phe-Ala-Ser
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259971
SABIO-RK:
13365
|
|
|
|
N-formyl-Nle-Gly(NH2) + H2O <=> formate + Nle-Gly(NH2)
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259972
SABIO-RK:
13366
|
|
|
|
N-formyl-Nle-Arg(NH2) + H2O <=> formate + Nle-Arg(NH2)
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259973
SABIO-RK:
13367
|
|
|
|
N-formyl-Nle-Ala(NH2) + H2O <=> formate + Nle-Ala(NH2)
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259974
SABIO-RK:
13378
|
|
|
|
N-formyl-Nle-Ser(NH2) + H2O <=> formate + Nle-Ser(NH2)
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259975
SABIO-RK:
13368
|
|
|
|
N-formyl-Nle-Asp(NH2) + H2O <=> formate + Nle-Asp(NH2)
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259976
SABIO-RK:
13369
|
|
|
|
N-formyl-Nle-Leu(NH2) + H2O <=> formate + Nle-Leu(NH2)
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259977
SABIO-RK:
13370
|
|
|
|
N-Formyl-Met-Leu-Phe + H2O <=> formate + Met-Leu-Phe
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259991
SABIO-RK:
13372
|
|
|
|
N-formyl-Met-Leu-Glu + H2O <=> formate + Met-Leu-Glu
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259992
SABIO-RK:
13373
|
|
|
|
N-formyl-Met-Ala(OCH3) + H2O <=> formate + Met-Ala(OCH3)
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259994
SABIO-RK:
13374
|
|
|
|
N-formyl-Nle-NH(CH3) + H2O <=> formate + Nle-NH(CH3)
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS259998
SABIO-RK:
13376
|
|
|
|
N-formyl-Met-Ser-Asn-Glu + H2O <=> formate + Met-Ser-Asn-Glu
|
3.5.1.88
peptide deformylase
|
–
|
|
|
BRENDA:
BS260002
SABIO-RK:
13371
|
|
|
|
1,2-dihydroxyhex-1-en-3-one + O2 <=> 2-Oxopentanoate + formate
|
1.13.11.54
acireductone dioxygenase [iron(II)-requiring]
|
–
|
|
|
BRENDA:
BS378826
SABIO-RK:
14839
|
|
|
|
1,2-dihydroxyhex-1-en-3-one + O2 <=> Butyrate + formate + CO
|
1.13.11.53
acireductone dioxygenase (Ni2+-requiring)
|
–
|
|
|
BRENDA:
BS378827
SABIO-RK:
14840
|
|
|
|
formaldehyde + H2O + methyl_viologen <=> formate + H+ + reduced_methyl_viologen
|
1.2.7.5
aldehyde ferredoxin oxidoreductase
1.2.7.B2
|
–
–
|
|
|
BRENDA:
BS388700
SABIO-RK:
11868
|
|
|
|
2,3-dihydro-2,3-dihydroxybenzoyl-CoA + H2O <=> 3,4-dehydroadipyl-CoA_semialdehyde + formate
|
4.1.2.44
2,3-epoxybenzoyl-CoA dihydrolase
|
–
|
|
|
BRENDA:
BS402317
SABIO-RK:
12865
|
|
|
|
ATP + formate + 5,6,7,8-tetrahydropteroylpentaglutamate <=> ADP + phosphate + 10-formyltetrahydrofolylpentaglutamate
|
6.3.4.3
formate---tetrahydrofolate ligase
|
–
|
|
|
BRENDA:
BS453773
SABIO-RK:
13997
|
|
|
|
cyanide + 2 H2O <=> NH3 + formate
|
3.5.5
|
–
|
K
|
|
KEGG:
R00152
|
|
|
|
4-carboxy-2-hydroxy-cis,cis-muconate_6-semialdehyde + H2O <=> 4-Methylene-2-oxoglutarate + formate
|
3.7.1
|
–
|
K
|
|
KEGG:
R04488
|
|
|
|
5-hydroxy-N-formylkynurenine + H2O <=> 5-hydroxy-L-kynurenine + formate
|
3.5.1.9
arylformamidase
|
–
|
K
|
|
KEGG:
R04911
|
|
|
|
Formamidopyrimidine_nucleoside_triphosphate + H2O <=> 2,5-diaminopyrimidine_nucleoside_triphosphate + formate
|
3.5.4.16
GTP cyclohydrolase I
|
–
|
K
|
|
KEGG:
R05046
|
|
|
|
2-Hydroxy-5-methyl-cis,cis-muconic_semialdehyde + H2O <=> formate + (4E)-2-Oxohexenoic_acid
|
3.7.1.9
2-hydroxymuconate-6-semialdehyde hydrolase
|
–
|
|
|
KEGG:
R05296
|
|
|
|
2-Hydroxy-5-methyl-cis,cis-muconic_semialdehyde + H2O <=> formate + (2E,4Z)-2-hydroxyhexa-2,4-dienoate
|
3.7.1.9
2-hydroxymuconate-6-semialdehyde hydrolase
|
–
|
K
|
|
KEGG:
R05865
|
|
|
|
N-cyclohexylformamide + H2O <=> Cyclohexylamine + formate
|
3.5.1
|
–
|
K
|
|
KEGG:
R06940
|
|
|
|
formate <=> CO2
|
not assigned
|
–
|
|
|
KEGG:
R09094
|
|
|
|
2,2,3-trichlorooxirane <=> formate
|
not assigned
|
–
|
K
|
|
KEGG:
R09145
|
|
|
|
Trichloroethylene + O2 + 2 H2O + NADH + H+ <=> 2 formate + 3 Hydrochloric_acid + NAD+
|
1.14.12.11
toluene dioxygenase
|
–
|
K
|
|
KEGG:
R09152
|
|
|
|
cis-4-(8-Hydroxypyren-7-yl)-2-oxobut-3-enoate <=> 10-Oxabenzo[def]chrysen-9-one + formate
|
4.1.3
|
–
|
K
|
|
KEGG:
R09185
|
|
|
|
S-(hydroxymethyl)mycothiol + NAD+ + H2O <=> formate + mycothiol + NADH + H+
|
1.1.1.306
S-(hydroxymethyl)mycothiol dehydrogenase
|
–
|
|
|
KEGG:
R10301
|
|
|
|
Paspaline_B + NADPH + H+ + O2 <=> 12-Demethyl-11,12-dehydropaspaline + NADP+ + H2O + formate
|
1.14.13
|
–
|
K
|
|
KEGG:
R10356
|
|
|
|
Terpendole_E + 4 NADPH + 4 O2 + 4 H+ <=> 13-Desoxyterpendole_I + formate + 4 NADP+ + 5 H2O
|
1.14.13
|
–
|
K
|
|
KEGG:
R10376
|
|
|
|
obtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
1.14.13.70-RXN
|
|
|
|
2-hydroxymuconate-6-semialdehyde + H2O <=> (2Z)-2-hydroxypenta-2,4-dienoate + formate + H+
|
3.7.1.9
2-hydroxymuconate-6-semialdehyde hydrolase
|
–
|
M
|
|
MetaCyc:
3.7.1.9-RXN
|
|
|
|
Formyl-N-acetyl-5-methoxykynurenamine + H2O <=> N-acetyl-5-methoxykynurenamine + formate + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-11073
|
|
|
|
formate + electron-transfer_quinone + H+ <=> CO2 + electron-transfer_quinol
|
1.17.5.3
formate dehydrogenase-N
|
–
|
|
|
MetaCyc:
RXN-11237
|
|
|
|
Zymosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-11881
|
|
|
|
vinyl_acetate + H2O <=> allyl_alcohol + formate
|
3.1.1
|
–
|
|
|
MetaCyc:
RXN-12087
|
|
|
|
formate + oxidized_hydrogenase <=> CO2 + reduced_hydrogenase
|
1.17.98.e
|
–
|
M
|
|
MetaCyc:
RXN-12274
|
|
|
|
hexadecanal + O2 + NADPH + H+ <=> a_long-chain_alkane + formate + H2O + NADP+
|
4.1.99.5
aldehyde oxygenase (deformylating)
|
–
|
M
|
|
MetaCyc:
RXN-13262
|
|
|
|
Heptanal + H2O <=> hexane + formate + H+
|
4.1.99
|
–
|
|
|
MetaCyc:
RXN-13286
|
|
|
|
24,25-dihydrolanosterol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-13707
|
|
|
|
3-amino-4-hydroxybenzaldehyde + N-acetyl-L-cysteine + O2 <=> grixazone_A + H2O + formate + H+
|
1.10.3.15
grixazone synthase
|
–
|
M
|
|
MetaCyc:
RXN-13868
|
|
|
|
a_14alpha-methylsteroid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_DELTA14-steroid + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-13961
|
|
|
|
testosterone + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 17beta-estradiol + oxidized_[NADPH-hemoprotein_reductase] + H2O + formate + H+
|
1.14.14.14
aromatase
|
–
|
|
|
MetaCyc:
RXN-14744
|
|
|
|
4-androstene-3,17-dione + reduced_[NADPH-hemoprotein_reductase] + O2 <=> estrone + oxidized_[NADPH-hemoprotein_reductase] + H2O + formate + H+
|
1.14.14.14
aromatase
|
–
|
|
|
MetaCyc:
RXN-14746
|
|
|
|
2-formylaminobenzaldehyde + H2O <=> 2-Aminobenzaldehyde + formate + H+
|
3.5.1
|
–
|
M
|
|
MetaCyc:
RXN-15187
|
|
|
|
Paspaline + O2 + reduced_[NADPH-hemoprotein_reductase] <=> beta-PC-M6 + formate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-15499
|
|
|
|
Terpendole_G + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Terpendole_B + oxidized_[NADPH-hemoprotein_reductase] + formate + H2O + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-15957
|
|
|
|
gamma-L-glutamyl-(S)-2-carboxypropyl-L-cysteine <=> gamma-L-glutamyl-(S)-trans-1-propenyl-L-cysteine + formate
|
4.1.99
|
–
|
M
|
|
MetaCyc:
RXN-16191
|
|
|
|
(R)-N-formyl-beta-hydroxy-L-kynurenine + H2O <=> (R)-beta-hydroxy-L-kynurenine + formate + H+
|
3.5.1.9
arylformamidase
|
–
|
M
|
|
MetaCyc:
RXN-17150
|
|
|
|
2,4,6-trioxohexanoate + H2O <=> Acetopyruvate + formate + H+
|
3.7.1.M3
|
–
|
|
|
MetaCyc:
RXN-17561
|
|
|
|
tert-butyl_formate + H2O <=> tert-butanol + formate + H+
|
3.7.1
|
–
|
M
|
|
MetaCyc:
RXN-17615
|
|
|
|
S-formylbacillithiol + H2O <=> bacillithiol + formate + H+
|
3.13.1
|
–
|
M
|
|
MetaCyc:
RXN-18815
|
|
|
|
Terpendole_E + reduced_[NADPH-hemoprotein_reductase] + O2 <=> Terpendole_B + oxidized_[NADPH-hemoprotein_reductase] + H2O + formate + H+
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-19725
|
|
|
|
a_14alpha-formylsteroid + O2 + reduced_[NADPH-hemoprotein_reductase] <=> a_DELTA14-steroid + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19830
|
|
|
|
30-oxoobtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-19833
|
|
|
|
intermediate_IV <=> akuammicine + formate + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19980
|
|
|
|
oxolanosterol + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + oxidized_ferredoxin + H2O + formate
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20129
|
|
|
|
4alpha,14alpha-dimethyl-cholesta-8-enol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-cholesta-8,14-dienol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
MetaCyc:
RXN-20438
|
|
|
|
4alpha,_14alpha-dimethyl_ergosta-8,25(27)-dienol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl_ergosta-8,14,25(27)-trienol + formate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
M
|
|
MetaCyc:
RXN-20445
|
|
|
|
2-hydroxy-5-methyl-6-oxohexa-2,4-dienoate + H2O <=> (2Z)-2-hydroxyhexa-2,5-dienoate + formate + H+
|
3.7.1.25
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase
|
–
|
M
|
|
MetaCyc:
RXN-20763
|
|
|
|
4alpha-formyl-14alpha-methyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21167
|
|
|
|
4alpha-formyl-14alpha-methyl-cholesta-8-enol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-cholesta-8,14-dienol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21170
|
|
|
|
formaldehyde + mycofactocinone + H2O <=> formate + mycofactocinol + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-21248
|
|
|
|
5-formyl-5,6,7,8-tetrahydromethanopterin + H2O <=> H+ + formate + 5,6,7,8-tetrahydromethanopterin
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-2884
|
|
|
|
4,5-dihydro-4-oxo-5-imidazolepropanoate + O2 + H2O + reduced_acceptor <=> 4-oxoglutaramate + NH3 + formate + acceptor
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-7593
|
|
|
|
dichlorocarbene + H2O <=> H+ + formate + Cl-
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8408
|
|
|
|
formate + oxidized_hydrogenase_3 <=> CO2 + reduced_hydrogenase_3
|
1.17.98.e
|
–
|
M
|
|
MetaCyc:
RXN0-3281
|
|
|
|
CO2 + H+ + e- <=> formate
|
not assigned
|
–
|
|
|
MetaCyc:
RXN0-5253
|
|
|
|
S-formylmycothiol + H2O <=> H+ + mycothiol + formate
|
3.13.1
|
–
|
M
|
|
MetaCyc:
RXN1G-129
|
|
|
|