|
|
reduced_flavodoxin + N2 + ATP + H2O <=> flavin + NH3 + H2 + ADP + phosphate + H+
|
1.19.6.1
nitrogenase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR40513
KEGG:
R05186
MetaCyc:
NITROGENASE-FLAVODOXIN-RXN
|
|
|
|
L-arginine + reduced_flavodoxin + O2 <=> L-citrulline + NO + flavin + H2O + H+
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
K
|
|
BRENDA:
BR40515
KEGG:
R11711
MetaCyc:
RXN-13568
|
|
|
|
reduced_flavodoxin + NAD+ <=> flavin + NADH + H+
|
1.5.1.36
flavin reductase (NADH)
|
–
|
|
|
BRENDA:
BR49640
KEGG:
R09662
MetaCyc:
RXN-12446
|
|
|
|
Nomega-hydroxy-L-arginine + reduced_flavodoxin + O2 <=> L-citrulline + NO + flavin + H2O + H+
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR50159
KEGG:
R11713
MetaCyc:
RXN-13567
|
|
|
|
a_7-oxoheptanoyl-[acyl-carrier_protein] + flavin + H2O <=> pimeloyl-[acyl-carrier_protein] + reduced_flavodoxin + H+
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
|
|
BRENDA:
BR50377
MetaCyc:
RXN-13837
|
|
|
|
(E)-4-hydroxy-3-methylbut-2-en-1-yl_diphosphate + flavin + H2O + H+ <=> 2-C-methyl-D-erythritol_2,4-cyclodiphosphate + reduced_flavodoxin
|
1.17.7.3
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR51177
KEGG:
R10859
MetaCyc:
RXN-15878
|
|
|
|
reduced_flavodoxin + NADP+ <=> flavin + NADPH + H+
|
1.19.1.1
flavodoxin---NADP+ reductase
1.6.2.4
NADPH---hemoprotein reductase
|
–
–
|
|
|
BRENDA:
BR51843
KEGG:
R08551;
R11485
MetaCyc:
FLAVONADPREDUCT-RXN
|
|
|
|
S-adenosyl-L-methionine + heme + reduced_flavodoxin <=> anaerobilin + L-methionine + 5''-deoxyadenosine + S-adenosyl-L-homocysteine + Fe2+ + flavin
|
2.1.1.342
anaerobilin synthase
|
–
|
M
|
|
BRENDA:
BR52055
KEGG:
R11700
MetaCyc:
RXN-18337
|
|
|
|
L-arginine + reduced_flavodoxin + O2 <=> Nomega-hydroxy-L-arginine + flavin + H2O
|
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
|
MK
|
|
BRENDA:
BR52113
KEGG:
R11712
MetaCyc:
RXN-13566
|
|
|
|
S-adenosyl-L-methionine + menaquinone + reduced_flavodoxin <=> an_8-methylmenaquinone + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
M
|
|
BRENDA:
BR52531
KEGG:
R12238
MetaCyc:
RXN-18515
|
|
|
|
S-adenosyl-L-methionine + 2-demethylmenaquinone + reduced_flavodoxin <=> a_2-demethyl-8-methylmenaquinone + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
BRENDA:
BR52532
KEGG:
R12239
MetaCyc:
RXN-18518
|
|
|
|
S-adenosyl-L-methionine + menaquinone-6 + reduced_flavodoxin <=> 8-methylmenaquinone-6 + S-adenosyl-L-homocysteine + L-methionine + 5''-deoxyadenosine + flavin + H+
|
2.1.1.350
menaquinone C8-methyltransferase
|
–
|
|
|
BRENDA:
BS444604
MetaCyc:
RXN-18516
|
|
|
|
2-methylbutanoyl-CoA + flavin <=> tigloyl-CoA + reduced_flavodoxin + H+
|
1.3.8.5
2-methyl-branched-chain-enoyl-CoA reductase
1.3.99.12
2-methylacyl-CoA dehydrogenase
|
–
–
|
|
|
BRENDA:
BR1200
KEGG:
R03169
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> 7alpha-hydroxycholesterol + flavin + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
BK
|
|
BRENDA:
BR29138
KEGG:
R01463
|
|
|
|
(S)-N-methylcanadine + reduced_flavodoxin + O2 <=> Allocryptopine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
K
|
|
BRENDA:
BR29140
KEGG:
R03842
|
|
|
|
formononetin + reduced_flavodoxin + O2 <=> Calycosin + flavin + H2O
|
1.14.14.88
isoflavone 3'-hydroxylase
|
–
|
K
|
|
BRENDA:
BR29141
KEGG:
R03006
|
|
|
|
formononetin + reduced_flavodoxin + O2 <=> 2''-hydroxyformononetin + flavin + H2O
|
1.14.14.89
4'-methoxyisoflavone 2'-hydroxylase
1.14.14.90
isoflavone 2'-hydroxylase
|
–
–
|
K
|
|
BRENDA:
BR29142
KEGG:
R06560
|
|
|
|
Quinine + reduced_flavodoxin + O2 <=> 3-hydroxyquinine + flavin + H2O
|
1.14.14.55
quinine 3-monooxygenase
|
–
|
|
|
BRENDA:
BR29143
KEGG:
R05727
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + O2 <=> (S)-4-hydroxymandelonitrile + flavin + 2 H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
K
|
|
BRENDA:
BR29144
KEGG:
R05728
|
|
|
|
a_14alpha-methylsteroid + 3 reduced_flavodoxin + 3 O2 <=> a_DELTA14-steroid + formate + 3 flavin + 4 H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
|
BRENDA:
BR29146
KEGG:
R12118
|
|
|
|
(S)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> (S)-3''-hydroxy-N-methylcoclaurine + flavin + H2O
|
1.14.14.102
N-methylcoclaurine 3'-monooxygenase
|
–
|
K
|
|
BRENDA:
BR29147
KEGG:
R05732
|
|
|
|
trans-cinnamate + reduced_flavodoxin + O2 <=> p-coumaric_acid + flavin + H2O
|
1.14.14.91
trans-cinnamate 4-monooxygenase
|
–
|
BK
|
|
BRENDA:
BR33713
KEGG:
R02253
|
|
|
|
17alpha-hydroxyprogesterone + reduced_flavodoxin + O2 <=> 4-androstene-3,17-dione + acetate + flavin + H2O
|
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
|
BK
|
|
BRENDA:
BR362
KEGG:
R08518
|
|
|
|
demethylmedicarpin + reduced_flavodoxin + O2 <=> (6aS,11aS)-3,6a,9-trihydroxypterocarpan + flavin + H2O
|
1.14.14.93
3,9-dihydroxypterocarpan 6a-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36760
KEGG:
R03452
|
|
|
|
leukotriene_B4 + reduced_flavodoxin + O2 <=> 20-hydroxy-leukotriene_B4 + flavin + H2O
|
1.14.14.78
phylloquinone omega-hydroxylase
1.14.14.94
leukotriene-B4 20-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR36761
KEGG:
R03866
|
|
|
|
L-tyrosine + O2 + reduced_flavodoxin <=> N-hydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36762
KEGG:
R00730
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (-)-trans-isopiperitenol + flavin + H2O
|
1.14.14.99
(S)-limonene 3-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36763
KEGG:
R02469
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (-)-trans-carveol + flavin + H2O
|
1.14.14.51
(S)-limonene 6-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36764
KEGG:
R02468
|
|
|
|
(-)-limonene + reduced_flavodoxin + O2 <=> (S)-perillyl_alcohol + flavin + H2O
|
1.14.14.52
(S)-limonene 7-monooxygenase
|
–
|
K
|
|
BRENDA:
BR36765
KEGG:
R02470
|
|
|
|
A + reduced_flavodoxin + O2 <=> rhodopsin + flavin + H2O
|
1.14.13.231
tetracycline 11a-monooxygenase
1.14.14.1
unspecific monooxygenase
|
–
–
|
|
|
BRENDA:
BR36767
KEGG:
R04122
|
|
|
|
linalool + 2 reduced_flavodoxin + 2 O2 <=> (6E)-8-oxolinalool + 2 flavin + 3 H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
|
|
BRENDA:
BR36768
KEGG:
R09925
|
|
|
|
isovaleryl-CoA + flavin <=> 3-methylcrotonoyl-CoA + reduced_flavodoxin
|
1.3.8.4
isovaleryl-CoA dehydrogenase
|
–
|
|
|
BRENDA:
BR36848
KEGG:
R04096
|
|
|
|
butyryl-CoA + flavin <=> crotonyl-CoA + reduced_flavodoxin
|
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
|
–
–
–
–
|
|
|
BRENDA:
BR36851
KEGG:
R01178
|
|
|
|
glutaryl-CoA + flavin <=> crotonyl-CoA + CO2 + reduced_flavodoxin
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
BK
|
|
BRENDA:
BR36856
KEGG:
R02488
|
|
|
|
reduced_flavodoxin + ubiquinone <=> flavin + ubiquinol
|
1.5.5.1
electron-transferring-flavoprotein dehydrogenase
|
–
|
|
|
BRENDA:
BR36912;
BS259373
KEGG:
R04433
|
|
|
|
sarcosine + H2O + flavin <=> glycine + formaldehyde + reduced_flavodoxin
|
1.5.8.3
sarcosine dehydrogenase
|
–
|
K
|
|
BRENDA:
BR36913
KEGG:
R00611
|
|
|
|
N,N-dimethylglycine + tetrahydrofolate + flavin <=> sarcosine + 5,10-methylenetetrahydrofolate + reduced_flavodoxin
|
1.5.8.4
dimethylglycine dehydrogenase
|
–
|
K
|
|
BRENDA:
BR36914
KEGG:
R01565
|
|
|
|
(S)-N-methylcoclaurine + (R)-N-methylcoclaurine + reduced_flavodoxin + O2 <=> Berbamunine + flavin + 2 H2O
|
1.14.19.66
berbamunine synthase
|
–
|
K
|
|
BRENDA:
BR36941
KEGG:
R04694
|
|
|
|
(S)-tetrahydrocolumbamine + reduced_flavodoxin + O2 <=> (S)-canadine + flavin + 2 H2O
|
1.14.19.64
(S)-stylopine synthase
1.14.19.68
(S)-canadine synthase
1.14.19.73
(S)-nandinine synthase
|
–
–
–
|
K
|
|
BRENDA:
BR36946
KEGG:
R04400
|
|
|
|
(R)-reticuline + reduced_flavodoxin + O2 <=> salutaridine + flavin + 2 H2O
|
1.14.19.67
salutaridine synthase
|
–
|
K
|
|
BRENDA:
BR36966
KEGG:
R04696
|
|
|
|
Dimethylamine + H2O + flavin <=> methylamine + formaldehyde + reduced_flavodoxin
|
1.5.8.1
dimethylamine dehydrogenase
|
–
|
BK
|
|
BRENDA:
BR36967
KEGG:
R01588
|
|
|
|
trimethylamine + H2O + flavin <=> Dimethylamine + formaldehyde + reduced_flavodoxin
|
1.5.8.2
trimethylamine dehydrogenase
|
–
|
BK
|
|
BRENDA:
BR36968
KEGG:
R02511
|
|
|
|
(S)-cheilanthifoline + reduced_flavodoxin + O2 <=> (S)-Stylopine + flavin + 2 H2O
|
1.14.19.64
(S)-stylopine synthase
|
–
|
K
|
|
BRENDA:
BR37080
KEGG:
R04690
|
|
|
|
(S)-scoulerine + reduced_flavodoxin + O2 <=> (S)-cheilanthifoline + flavin + 2 H2O
|
1.14.19.65
(S)-cheilanthifoline synthase
|
–
|
K
|
|
BRENDA:
BR37081
KEGG:
R03834
|
|
|
|
5-O-p-coumaroylquinic_acid + reduced_flavodoxin + O2 <=> chlorogenic_acid + flavin + H2O
|
1.14.14.96
5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
|
–
|
BK
|
|
BRENDA:
BR37109
KEGG:
R04342
|
|
|
|
loganin + reduced_flavodoxin + O2 <=> secologanin + flavin + 2 H2O
|
1.14.19.62
secologanin synthase
|
–
|
K
|
|
BRENDA:
BR40360
KEGG:
R03555
|
|
|
|
squalene + reduced_flavodoxin + O2 <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + flavin + H2O
|
1.14.14.17
squalene monooxygenase
|
–
|
K
|
|
BRENDA:
BR40381
KEGG:
R02874
|
|
|
|
heme + 3 reduced_flavodoxin + 3 O2 <=> Biliverdin + Fe2+ + CO + 3 flavin + 3 H2O
|
1.14.14.18
heme oxygenase (biliverdin-producing)
1.14.99.58
heme oxygenase (biliverdin-IX-beta and delta-forming)
|
–
–
|
BK
|
|
BRENDA:
BR40384
KEGG:
R00311
|
|
|
|
taxa-4(20),11-dien-5alpha-yl_acetate + reduced_flavodoxin + O2 <=> 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl_acetate + flavin + H2O
|
1.14.14.105
taxane 10beta-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR40410
KEGG:
R06309
|
|
|
|
tabersonine + reduced_flavodoxin + O2 <=> 16-hydroxytabersonine + flavin + H2O
|
1.14.14.103
tabersonine 16-hydroxylase
|
–
|
K
|
|
BRENDA:
BR40411
KEGG:
R05855
|
|
|
|
flavonoids + reduced_flavodoxin + O2 <=> a_3''-hydroxyflavonoid + flavin + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
|
|
BRENDA:
BR40432
KEGG:
R03615
|
|
|
|
vinorine + reduced_flavodoxin + O2 <=> Vomilenine + flavin + H2O
|
1.14.14.104
vinorine hydroxylase
|
–
|
K
|
|
BRENDA:
BR40519
KEGG:
R05877
|
|
|
|
benzoate + reduced_flavodoxin + O2 <=> 4-hydroxybenzoate + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.92
benzoate 4-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR40521
KEGG:
R01295
|
|
|
|
taxa-4,11-diene + reduced_flavodoxin + O2 <=> taxa-4(20),11-dien-5alpha-ol + flavin + H2O
|
1.14.14.176
taxadiene 5alpha-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR40524
KEGG:
R06306
|
|
|
|
ent-kaur-16-ene + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-ol + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
K
|
|
BRENDA:
BR40525
KEGG:
R06291
|
|
|
|
ent-kaur-16-en-19-ol + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-al + flavin + 2 H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
K
|
|
BRENDA:
BR40526
KEGG:
R06292
|
|
|
|
ent-kaur-16-en-19-al + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-oate + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
K
|
|
BRENDA:
BR40527
KEGG:
R06293
|
|
|
|
7-deoxyloganate + reduced_flavodoxin + O2 <=> loganic_acid + flavin + H2O
|
1.14.14.85
7-deoxyloganate 7-hydroxylase
|
–
|
K
|
|
BRENDA:
BR40528
KEGG:
R05832
|
|
|
|
ent-kaur-16-en-19-oate + reduced_flavodoxin + O2 <=> ent-7alpha-hydroxykaur-16-en-19-oate + flavin + H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
K
|
|
BRENDA:
BR40543
KEGG:
R06294
|
|
|
|
ent-7alpha-hydroxykaur-16-en-19-oate + reduced_flavodoxin + O2 <=> gibberellin_A12_aldehyde + flavin + 2 H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
K
|
|
BRENDA:
BR40544
KEGG:
R06295
|
|
|
|
gibberellin_A12_aldehyde + reduced_flavodoxin + O2 <=> gibberellin_A12 + flavin + H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
K
|
|
BRENDA:
BR40545
KEGG:
R06297
|
|
|
|
N-hydroxy-L-tyrosine + O2 + reduced_flavodoxin <=> N,N-dihydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR47356
KEGG:
R04460
|
|
|
|
(R)-2-benzylsuccinyl-CoA + flavin <=> (E)-2-benzylidenesuccinyl-CoA + reduced_flavodoxin
|
1.3.8.3
(R)-benzylsuccinyl-CoA dehydrogenase
|
–
|
BK
|
|
BRENDA:
BR47377
KEGG:
R05584
|
|
|
|
(+)-limonene + reduced_flavodoxin + O2 <=> (+)-trans-carveol + flavin + H2O
|
1.14.14.53
(R)-limonene 6-monooxygenase
|
–
|
K
|
|
BRENDA:
BR47606
KEGG:
R06119
|
|
|
|
(6aS,11aS)-2-dimethylallyl-3,6a,9-trihydroxypterocarpan + reduced_flavodoxin + O2 <=> glyceollin_II + flavin + 2 H2O
|
1.14.14.135
glyceollin synthase
|
–
|
K
|
|
BRENDA:
BR48493
KEGG:
R07195
|
|
|
|
a_flavanone + reduced_flavodoxin + O2 <=> a_3''-hydroxyflavanone + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BR48495
KEGG:
R07369
|
|
|
|
a_3''-hydroxyflavanone + reduced_flavodoxin + O2 <=> a_3'',5''-dihydroxyflavanone + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
|
|
BRENDA:
BR48496
KEGG:
R07370
|
|
|
|
25-hydroxycholesterol + reduced_flavodoxin + O2 <=> 7alpha,25-Dihydroxycholesterol + flavin + H2O
|
1.14.14.29
25/26-hydroxycholesterol 7alpha-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48561
KEGG:
R07209
|
|
|
|
(24S)-24-hydroxycholesterol + reduced_flavodoxin + O2 <=> (24S)-cholest-5-ene-3beta,7alpha,24-triol + flavin + H2O
|
1.14.14.26
24-hydroxycholesterol 7alpha-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48563
KEGG:
R07208
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> (24S)-24-hydroxycholesterol + flavin + H2O
|
1.14.14.25
cholesterol 24-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48564
KEGG:
R07207
|
|
|
|
taurochenodeoxycholate + reduced_flavodoxin + O2 <=> taurohyocholate + flavin + H2O
|
1.14.14.57
taurochenodeoxycholate 6alpha-hydroxylase
|
–
|
|
|
BRENDA:
BR48565
KEGG:
R07205
|
|
|
|
lithocholic_acid + reduced_flavodoxin + O2 <=> hyodeoxycholic_acid + flavin + H2O
|
1.14.14.57
taurochenodeoxycholate 6alpha-hydroxylase
|
–
|
|
|
BRENDA:
BR48566
KEGG:
R07206
|
|
|
|
5beta-cholestane-3alpha,7alpha-diol + reduced_flavodoxin + O2 <=> 5beta-cholestane-3alpha,7alpha,12alpha-triol + flavin + H2O
|
1.14.14.139
5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48567
KEGG:
R07204
|
|
|
|
lithocholic_acid + reduced_flavodoxin + O2 <=> 6beta-hydroxylithocholate + flavin + H2O
|
1.14.14.138
lithocholate 6beta-hydroxylase
|
–
|
|
|
BRENDA:
BR48569
KEGG:
R07203
|
|
|
|
abscisic_acid + reduced_flavodoxin + O2 <=> 8''-hydroxyabscisate + flavin + H2O
|
1.14.14.137
(+)-abscisic acid 8'-hydroxylase
|
–
|
K
|
|
BRENDA:
BR48570
KEGG:
R07202
|
|
|
|
an_isoflavone + reduced_flavodoxin + O2 <=> a_2''-hydroxyisoflavone + flavin + H2O
|
1.14.14.90
isoflavone 2'-hydroxylase
|
–
|
|
|
BRENDA:
BR48603
KEGG:
R07371
|
|
|
|
2 ATP + 2 cob(II)yrinic_acid_a,c-diamide + reduced_flavodoxin <=> 2 tripolyphosphate + 2 adenosylcobyrinic_acid_a,c-diamide + flavin
|
2.5.1.17
corrinoid adenosyltransferase
|
–
|
K
|
|
BRENDA:
BR48626
KEGG:
R12184
|
|
|
|
2 ATP + 2 Cobalamin + reduced_flavodoxin <=> 2 tripolyphosphate + 2 adenosylcobalamin + flavin
|
2.5.1.17
corrinoid adenosyltransferase
|
–
|
|
|
BRENDA:
BR48627
KEGG:
R12183
|
|
|
|
10-deoxysarpagine + reduced_flavodoxin + O2 <=> sarpagine + flavin + H2O
|
1.14.14.136
deoxysarpagine hydroxylase
|
–
|
K
|
|
BRENDA:
BR48709
KEGG:
R05828
|
|
|
|
(+)-marmesin + reduced_flavodoxin + O2 <=> psoralen + flavin + acetone + 2 H2O
|
1.14.14.141
psoralen synthase
|
–
|
|
|
BRENDA:
BR48846
KEGG:
R08207
|
|
|
|
sophoraflavanone_B + reduced_flavodoxin + O2 <=> leachianone_G + flavin + H2O
|
1.14.14.142
8-dimethylallylnaringenin 2'-hydroxylase
|
–
|
|
|
BRENDA:
BR48847
KEGG:
R08922
|
|
|
|
(R)-pulegone + reduced_flavodoxin + O2 <=> (+)-menthofuran + flavin + H2O
|
1.14.14.143
(+)-menthofuran synthase
|
–
|
K
|
|
BRENDA:
BR48926
KEGG:
R08923
|
|
|
|
abieta-7,13-diene + reduced_flavodoxin + O2 <=> abietadienol + flavin + H2O
|
1.14.14.144
abieta-7,13-diene hydroxylase
|
–
|
K
|
|
BRENDA:
BR49044
KEGG:
R06351
|
|
|
|
abietadienol + 2 reduced_flavodoxin + 2 O2 <=> abietic_acid + 2 flavin + 3 H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BR49045
KEGG:
R12122
|
|
|
|
geranylgeraniol + reduced_flavodoxin + O2 <=> 18-hydroxygeranylgeraniol + flavin + H2O
|
1.14.14.146
geranylgeraniol 18-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49046
KEGG:
R09122
|
|
|
|
3-epi-6-deoxocathasterone + reduced_flavodoxin + O2 <=> 6-deoxotyphasterol + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49134
KEGG:
R07792
|
|
|
|
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + reduced_flavodoxin + O2 <=> 3-dehydro-6-deoxoteasterone + flavin + H2O
|
1.14.14.147
3-epi-6-deoxocathasterone 23-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49135
KEGG:
R07791
|
|
|
|
(+)-columbianetin + reduced_flavodoxin + O2 <=> angelicin + flavin + acetone + 2 H2O
|
1.14.14.148
angelicin synthase
|
–
|
|
|
BRENDA:
BR49215
KEGG:
R09002
|
|
|
|
geranylhydroquinone + reduced_flavodoxin + O2 <=> 3''''-hydroxygeranylhydroquinone + flavin + H2O
|
1.14.14.174
geranylhydroquinone 3''-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49271
KEGG:
R09042
|
|
|
|
L-isoleucine + 2 reduced_flavodoxin + 2 O2 <=> (1E,2S)-2-methylbutanal_oxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.39
isoleucine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49376
KEGG:
R09403
|
|
|
|
L-isoleucine + reduced_flavodoxin + O2 <=> N-hydroxy-L-isoleucine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR49377
KEGG:
R10027
|
|
|
|
N-hydroxy-L-isoleucine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-isoleucine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR49378
KEGG:
R10028
|
|
|
|
L-valine + 2 reduced_flavodoxin + 2 O2 <=> (E/Z)-isobutyraldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.38
valine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49380
KEGG:
R08663
|
|
|
|
L-valine + reduced_flavodoxin + O2 <=> N-hydroxy-L-valine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR49381
KEGG:
R10031
|
|
|
|
N-hydroxy-L-valine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-valine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BR49382
KEGG:
R10032
|
|
|
|
5-epiaristolochene + 2 reduced_flavodoxin + 2 O2 <=> capsidiol + 2 flavin + 2 H2O
|
1.14.14.149
5-epiaristolochene 1,3-dihydroxylase
|
–
|
K
|
|
BRENDA:
BR49418
KEGG:
R09573
|
|
|
|
germacra-1(10),4,11(13)-trien-12-oate + reduced_flavodoxin + O2 <=> (+)-costunolide + flavin + 2 H2O
|
1.14.14.150
costunolide synthase
|
–
|
K
|
|
BRENDA:
BR49419
KEGG:
R09575
|
|
|
|
(-)-vetispiradiene + reduced_flavodoxin + O2 <=> solavetivol + flavin + H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
K
|
|
BRENDA:
BR49420
KEGG:
R09576
|
|
|
|
solavetivol + reduced_flavodoxin + O2 <=> solavetivone + flavin + 2 H2O
|
1.14.14.151
premnaspirodiene oxygenase
|
–
|
K
|
|
BRENDA:
BR49421
KEGG:
R09577
|
|
|
|
Calycosin + reduced_flavodoxin + O2 <=> pseudobaptigenin + flavin + 2 H2O
|
1.14.19.63
pseudobaptigenin synthase
|
–
|
K
|
|
BRENDA:
BR49422
KEGG:
R07745
|
|
|
|
Pratensein + reduced_flavodoxin + O2 <=> 5-hydroxypseudobaptigenin + flavin + 2 H2O
|
1.14.19.63
pseudobaptigenin synthase
|
–
|
K
|
|
BRENDA:
BR49423
KEGG:
R09602
|
|
|
|
germacrene_A + 3 reduced_flavodoxin + 3 O2 <=> germacra-1(10),4,11(13)-trien-12-oate + 3 flavin + 4 H2O
|
1.14.14.95
germacrene A hydroxylase
|
–
|
|
|
BRENDA:
BR49588
KEGG:
R12128
|
|
|
|
L-phenylalanine + 2 reduced_flavodoxin + 2 O2 <=> (E)-phenylacetaldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49589
KEGG:
R09578
|
|
|
|
L-phenylalanine + reduced_flavodoxin + O2 <=> N-hydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49590
KEGG:
R09579
|
|
|
|
N-hydroxy-L-phenylalanine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49591
KEGG:
R09580
|
|
|
|
L-tryptophan + 2 reduced_flavodoxin + 2 O2 <=> (E,Z)-indolyl-3-acetaldoxime + 2 flavin + CO2 + 3 H2O
|
1.14.14.156
tryptophan N-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49593
KEGG:
R08160
|
|
|
|
L-tryptophan + reduced_flavodoxin + O2 <=> N-hydroxy-L-tryptophan + flavin + H2O
|
1.14.14.156
tryptophan N-monooxygenase
|
–
|
|
|
BRENDA:
BR49594
KEGG:
R09583
|
|
|
|
N-hydroxy-L-tryptophan + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-tryptophan + flavin + H2O
|
1.14.14.156
tryptophan N-monooxygenase
|
–
|
|
|
BRENDA:
BR49595
KEGG:
R09584
|
|
|
|
beta-amyrin + reduced_flavodoxin + O2 <=> 24-hydroxy-beta-amyrin + flavin + H2O
|
1.14.14.134
beta-amyrin 24-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49606
KEGG:
R09604
|
|
|
|
sophoradiol + reduced_flavodoxin + O2 <=> soyasapogenol_B + flavin + H2O
|
1.14.14.134
beta-amyrin 24-hydroxylase
|
–
|
|
|
BRENDA:
BR49607
KEGG:
R09605
|
|
|
|
alpha-carotene + reduced_flavodoxin + O2 <=> alpha-cryptoxanthin + flavin + H2O
|
1.14.14.158
carotenoid epsilon hydroxylase
|
–
|
K
|
|
BRENDA:
BR49609
KEGG:
R07850
|
|
|
|
beta-amyrin + 2 reduced_flavodoxin + 2 O2 <=> 11-oxo-beta-amyrin + 2 flavin + 3 H2O
|
1.14.14.152
beta-amyrin 11-oxidase
|
–
|
|
|
BRENDA:
BR49822
KEGG:
R09817
|
|
|
|
beta-amyrin + reduced_flavodoxin + O2 <=> 11alpha-hydroxy-beta-amyrin + flavin + H2O
|
1.14.14.152
beta-amyrin 11-oxidase
|
–
|
|
|
BRENDA:
BR49823
KEGG:
R09815
|
|
|
|
11alpha-hydroxy-beta-amyrin + reduced_flavodoxin + O2 <=> 11-oxo-beta-amyrin + flavin + 2 H2O
|
1.14.14.152
beta-amyrin 11-oxidase
|
–
|
|
|
BRENDA:
BR49824
KEGG:
R09816
|
|
|
|
liquiritigenin + O2 + reduced_flavodoxin <=> 2,4'',7-trihydroxyisoflavanone + H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
K
|
|
BRENDA:
BR49825
KEGG:
R07777
|
|
|
|
abietadienol + reduced_flavodoxin + O2 <=> abieta-7,13-dien-18,18-diol + flavin + H2O
|
1.14.14.145
abieta-7,13-dien-18-ol hydroxylase
|
–
|
|
|
BRENDA:
BR49967
KEGG:
R10077
|
|
|
|
indole + reduced_flavodoxin + O2 <=> indolin-2-one + flavin + H2O
|
1.14.14.153
indole-2-monooxygenase
|
–
|
K
|
|
BRENDA:
BR49969
KEGG:
R07403
|
|
|
|
indolin-2-one + reduced_flavodoxin + O2 <=> 3-hydroxyindolin-2-one + flavin + H2O
|
1.14.14.157
indolin-2-one monooxygenase
|
–
|
K
|
|
BRENDA:
BR49970
KEGG:
R07421
|
|
|
|
3-hydroxyindolin-2-one + reduced_flavodoxin + O2 <=> 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + flavin + H2O
|
1.14.14.109
3-hydroxyindolin-2-one monooxygenase
|
–
|
K
|
|
BRENDA:
BR49971
KEGG:
R07422
|
|
|
|
ent-isokaurene + 2 O2 + 2 reduced_flavodoxin <=> ent-isokaurene-2beta,3beta-diol + flavin + 2 H2O
|
1.14.14.76
ent-isokaurene C2/C3-hydroxylase
|
–
|
|
|
BRENDA:
BR49975
KEGG:
R12058
|
|
|
|
9beta-pimara-7,15-diene + 3 O2 + 3 reduced_flavodoxin <=> 9beta-pimara-7,15-dien-19-oate + 3 flavin + 4 H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
K
|
|
BRENDA:
BR49976
KEGG:
R09865
|
|
|
|
9beta-pimara-7,15-diene + O2 + reduced_flavodoxin <=> 9beta-pimara-7,15-dien-19-ol + flavin + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BR49977
KEGG:
R09862
|
|
|
|
9beta-pimara-7,15-dien-19-ol + O2 + reduced_flavodoxin <=> 9beta-pimara-7,15-dien-19-al + flavin + 2 H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BR49978
KEGG:
R09863
|
|
|
|
9beta-pimara-7,15-dien-19-al + O2 + reduced_flavodoxin <=> 9beta-pimara-7,15-dien-19-oate + flavin + H2O
|
1.14.14.111
9beta-pimara-7,15-diene oxidase
|
–
|
|
|
BRENDA:
BR49979
KEGG:
R09864
|
|
|
|
ent-cassa-12,15-diene + O2 + reduced_flavodoxin <=> ent-11beta-hydroxycassa-12,15-diene + flavin + H2O
|
1.14.14.112
ent-cassa-12,15-diene 11-hydroxylase
|
–
|
K
|
|
BRENDA:
BR49980
KEGG:
R09866
|
|
|
|
alpha-humulene + O2 + reduced_flavodoxin <=> 10-hydroxy-alpha-humulene + flavin + H2O
|
1.14.14.113
alpha-humulene 10-hydroxylase
|
–
|
|
|
BRENDA:
BR50023
KEGG:
R09934
|
|
|
|
linalool + reduced_flavodoxin + O2 <=> (6E)-8-hydroxylinalool + flavin + H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
K
|
|
BRENDA:
BR50024
KEGG:
R04366;
R09923
|
|
|
|
(6E)-8-hydroxylinalool + reduced_flavodoxin + O2 <=> (6E)-8-oxolinalool + flavin + 2 H2O
|
1.14.14.84
linalool 8-monooxygenase
|
–
|
K
|
|
BRENDA:
BR50025
KEGG:
R09924
|
|
|
|
geraniol + reduced_flavodoxin + O2 <=> (6E)-8-hydroxygeraniol + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.83
geraniol 8-hydroxylase
|
–
–
|
K
|
|
BRENDA:
BR50026
KEGG:
R08785
|
|
|
|
glutaryl-CoA + flavin <=> glutaconyl-CoA + reduced_flavodoxin
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
B
|
|
BRENDA:
BR50093
KEGG:
R10074
|
|
|
|
1,8-cineole + reduced_flavodoxin + O2 <=> 2-exo-hydroxy-1,8-cineole + flavin + H2O
|
1.14.14.133
1,8-cineole 2-endo-monooxygenase
1.14.14.56
1,8-cineole 2-exo-monooxygenase
|
–
–
|
|
|
BRENDA:
BR50103;
BS418195
KEGG:
R10076
|
|
|
|
amorpha-4,11-diene + 3 O2 + 3 reduced_flavodoxin <=> artemisinate + 3 flavin + 4 H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
BRENDA:
BR50104
KEGG:
R10026
|
|
|
|
artemisinic_alcohol + O2 + reduced_flavodoxin <=> artemisinic_aldehyde + flavin + 2 H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
B
|
|
BRENDA:
BR50105
KEGG:
R10024
|
|
|
|
artemisinic_aldehyde + O2 + reduced_flavodoxin <=> artemisinate + flavin + H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
B
|
|
BRENDA:
BR50106
KEGG:
R10025
|
|
|
|
vitamin_D3 + O2 + reduced_flavodoxin <=> 25-hydroxyvitamin_D3 + flavin + H2O
|
1.14.14.24
vitamin D 25-hydroxylase
|
–
|
K
|
|
BRENDA:
BR50107
KEGG:
R03611
|
|
|
|
amorpha-4,11-diene + O2 + reduced_flavodoxin <=> artemisinic_alcohol + flavin + H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
B
|
|
BRENDA:
BR50356
KEGG:
R10023
|
|
|
|
ent-kaur-16-en-19-oate + 3 reduced_flavodoxin + 3 O2 <=> gibberellin_A12 + 3 flavin + 4 H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
|
|
BRENDA:
BR50357
KEGG:
R10067
|
|
|
|
stearoyl-[acyl-carrier_protein] + 2 reduced_flavodoxin + 3 O2 <=> pimeloyl-[acyl-carrier_protein] + an_n-alkanal + 2 flavin + 3 H2O
|
1.14.14.46
pimeloyl-[acyl-carrier protein] synthase
|
–
|
K
|
|
BRENDA:
BR50373
KEGG:
R10123
|
|
|
|
naringenin + O2 + reduced_flavodoxin <=> 2,4'',5,7-tetrahydroxyisoflavanone + H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
K
|
|
BRENDA:
BR50515
KEGG:
R07778
|
|
|
|
11-oxo-beta-amyrin + 3 O2 + 3 reduced_flavodoxin <=> glycyrrhetinic_acid + 3 flavin + 4 H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
BRENDA:
BR50517
KEGG:
R10316
|
|
|
|
11-oxo-beta-amyrin + O2 + reduced_flavodoxin <=> 30-hydroxy-11-oxo-beta-amyrin + flavin + H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
BRENDA:
BR50518
KEGG:
R10313
|
|
|
|
30-hydroxy-11-oxo-beta-amyrin + O2 + reduced_flavodoxin <=> glycyrrhetaldehyde + flavin + 2 H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
BRENDA:
BR50519
KEGG:
R10314
|
|
|
|
glycyrrhetaldehyde + O2 + reduced_flavodoxin <=> glycyrrhetinic_acid + flavin + H2O
|
1.14.14.115
11-oxo-beta-amyrin 30-oxidase
|
–
|
|
|
BRENDA:
BR50520
KEGG:
R10315
|
|
|
|
(1''S)-averantin + reduced_flavodoxin + O2 <=> (1''S,5''S)-5''-hydroxyaverantin + flavin + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
K
|
|
BRENDA:
BR50521
KEGG:
R10317
|
|
|
|
(1''S)-averantin + reduced_flavodoxin + O2 <=> (1''S,5''R)-5''-hydroxyaverantin + flavin + H2O
|
1.14.14.116
averantin hydroxylase
|
–
|
K
|
|
BRENDA:
BR50522
KEGG:
R10318
|
|
|
|
8-O-methylsterigmatocystin + 2 reduced_flavodoxin + 2 O2 <=> aflatoxin_B1 + 2 flavin + H2O + methanol + CO2
|
1.14.14.117
aflatoxin B synthase
|
–
|
K
|
|
BRENDA:
BR50523
KEGG:
R10319
|
|
|
|
8-O-methyldihydrosterigmatocystin + 2 reduced_flavodoxin + 2 O2 <=> Aflatoxin_B2 + 2 flavin + H2O + methanol + CO2
|
1.14.14.117
aflatoxin B synthase
|
–
|
K
|
|
BRENDA:
BR50524
KEGG:
R10320
|
|
|
|
tryprostatin_B + reduced_flavodoxin + O2 <=> 6-hydroxytryprostatin_B + flavin + H2O
|
1.14.14.118
tryprostatin B 6-hydroxylase
|
–
|
BK
|
|
BRENDA:
BR50525
KEGG:
R10321
|
|
|
|
fumitremorgin_C + 2 reduced_flavodoxin + 2 O2 <=> 12alpha,13alpha-dihydroxyfumitremorgin_C + 2 flavin + 2 H2O
|
1.14.14.119
fumitremorgin C monooxygenase
|
–
|
BK
|
|
BRENDA:
BR50576
KEGG:
R10414
|
|
|
|
tryprostatin_A + reduced_flavodoxin + O2 <=> fumitremorgin_C + flavin + 2 H2O
|
1.14.19.71
fumitremorgin C synthase
|
–
|
BK
|
|
BRENDA:
BR50590
KEGG:
R10416
|
|
|
|
testosterone + 3 O2 + 3 reduced_flavodoxin <=> 17beta-estradiol + formate + 4 H2O + 3 flavin
|
1.14.14.14
aromatase
|
–
|
|
|
BRENDA:
BR50742
KEGG:
R10511
|
|
|
|
testosterone + O2 + reduced_flavodoxin <=> 19-hydroxytestosterone + H2O + flavin
|
1.14.14.14
aromatase
|
–
|
K
|
|
BRENDA:
BR50743
KEGG:
R02501
|
|