|
|
deoxycholoyl-CoA + cholic_acid <=> choloyl-CoA + deoxycholate
|
2.8.3.25
bile acid CoA-transferase
|
–
|
|
| |
BRENDA:
BR51767
KEGG:
R07295
MetaCyc:
RXN-15366
|
|
|
|
deoxycholate + NAD+ <=> 12alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADH + H+
|
1.1.1
1.1.1.392
3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.52
3alpha-hydroxycholanate dehydrogenase (NAD+)
|
–
–
–
–
|
M
|
| |
BRENDA:
BS188317
MetaCyc:
RXN-17396;
RXN-21337_WOP
|
|
|
|
deoxycholate + NADP+ <=> 4-(1-Naphthylvinyl)pyridine + NADPH + H+
|
1.1.1.176
12alpha-hydroxysteroid dehydrogenase
|
–
|
|
| |
BRENDA:
BS230314
MetaCyc:
RXN-21346
|
|
|
|
deoxycholate + NADP+ <=> 12alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADPH + H+
|
1.1.1
1.1.1.392
3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
–
–
|
M
|
| |
BRENDA:
BS257233
MetaCyc:
RXN-17386;
RXN-21337
|
|
|
|
glycodeoxycholic_acid + H2O <=> deoxycholate + glycine
|
3.5.1.24
choloylglycine hydrolase
|
–
|
|
| |
BRENDA:
BS140401
KEGG:
R04486
|
|
|
|
taurodeoxycholate + H2O <=> deoxycholate + taurine
|
3.5.1.24
choloylglycine hydrolase
3.5.1.74
chenodeoxycholoyltaurine hydrolase
|
–
–
|
|
| |
BRENDA:
BS140403
KEGG:
R04487
|
|
|
|
3alpha,12alpha-dihydroxy-5beta-chol-6-enoate + 2 H+ <=> deoxycholate
|
not assigned
|
–
|
|
| |
KEGG:
R05836
|
|
|
|
deoxycholate + FAD + H2O <=> cholic_acid + FADH2
|
not assigned
|
–
|
|
| |
KEGG:
R07220
|
|
|
|
UDP-galactose + deoxycholate <=> beta-D-galactosyl-deoxycholate + UDP
|
2.4.1.M19
|
–
|
|
| |
MetaCyc:
RXN-18315
|
|
|
|
deoxycholate + Na+ <=> deoxycholate + Na+
|
not assigned
|
–
|
|
| |
MetaCyc:
TRANS-RXN-349
|
|
|
|
deoxycholate + H+ <=> deoxycholate + H+
|
not assigned
|
–
|
|
| |
MetaCyc:
TRANS-RXN-352
|
|
|
|
deoxycholate + H+ <=> deoxycholate + H+
|
not assigned
|
–
|
|
| |
MetaCyc:
TRANS-RXN-365
|
|
|
|
UDP-glucuronate + deoxycholate <=> UDP + deoxycholic_acid_24-beta-D-glucuronoside
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
| |
BRENDA:
BS436018
|
|
|
|
deoxycholate + UDP-glucuronate <=> UDP + deoxycholic_acid_O-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
| |
BRENDA:
BS322203
|
|
|
|
UDP-glucuronate + deoxycholate <=> UDP + hyodeoxycholic_acid_6-O-glucuronoside
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
| |
BRENDA:
BS399071
|
|
|
|
taurochenodeoxycholate + H2O <=> deoxycholate + taurine
|
3.5.1.24
choloylglycine hydrolase
|
–
|
|
| |
BRENDA:
BS415353
|
|
|
|
deoxycholate + NADH <=> 12alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NAD+
|
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
–
|
|
| |
BRENDA:
BS439487
|
|
|
|
deoxycholate + NAD+ <=> 4-(1-Naphthylvinyl)pyridine + NADH + H+
|
1.1.1.176
12alpha-hydroxysteroid dehydrogenase
|
–
|
|
| |
BRENDA:
BS230314-a
|
|
|
|
3''-phosphoadenylyl-sulfate + deoxycholate <=> adenosine_3'',5''-bisphosphate + deoxycholate_12-sulfate
|
2.8.2.14
bile-salt sulfotransferase
|
–
|
|
| |
BRENDA:
BS360188
|
|
|
|
3''-phosphoadenylyl_5''-phosphosulfate + deoxycholate <=> adenosine_3'',5''-bisphosphate + deoxycholate_3-sulfate
|
2.8.2.34
glycochenodeoxycholate sulfotransferase
|
–
|
|
| |
BRENDA:
BS375748
|
|
|
|
glycochenodeoxycholic_acid + H2O <=> deoxycholate + glycine
|
3.5.1.24
choloylglycine hydrolase
|
–
|
|
| |
BRENDA:
BS414668
|
|
|
|
deoxycholoyl-CoA + allocholate <=> deoxycholate + allocholoyl-CoA
|
2.8.3.25
bile acid CoA-transferase
|
–
|
|
| |
BRENDA:
BS437380
|
|
|
|
ATP + H2O + deoxycholate <=> ADP + phosphate + deoxycholate
|
7.6.2.2
ABC-type xenobiotic transporter
|
–
|
|
| |
BRENDA:
BS444996
|
|
|
|
ATP + deoxycholate + CoA <=> AMP + diphosphate + deoxycholoyl-CoA
|
6.2.1.7
cholate---CoA ligase
|
–
|
|
| |
BRENDA:
BS346
|
|
