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Your translated search: NADP+ = 5062 reactions were found.
State Icon Reaction EC-Number Conf. maximal confidence score from EnzymeDetector PW
Butyraldehyde + CoA + NADP+ <=> butyryl-CoA + NADPH + H+ 1.2.1.10 acetaldehyde dehydrogenase (acetylating)
1.2.1.57 butanal dehydrogenase
1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
–
–
–
MK
D-glyceraldehyde_3-phosphate + phosphate + NADP+ <=> 3-phospho-D-glyceroyl_phosphate + NADPH + H+ 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
–
–
–
–
BMK
(3R)-2''-hydroxydihydrodaidzein + NADP+ <=> 2''-hydroxydaidzein + NADPH + H+ 1.3.1.51 2'-hydroxydaidzein reductase
–
MK
Precorrin-6Y + NADP+ <=> precorrin-6A + NADPH + H+ 1.3.1.54 precorrin-6A reductase
–
BMK
(R)-reticuline + NADP+ <=> 1,2-dehydroreticuline + NADPH + H+ 1.5.1.27 1,2-dehydroreticulinium reductase (NADPH)
–
MK
H+ + 1,4-benzoquinone + NADPH <=> hydroquinone + NADP+ 1.1.1.328 nicotine blue oxidoreductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
1.7.1.6 azobenzene reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
–
BMK
L-lysine + O2 + NADPH <=> N6-hydroxy-L-lysine + NADP+ + H2O 1.14.13.59 L-lysine N6-monooxygenase (NADPH)
–
BMK
9-fluorenol + NADP+ <=> 9-fluorenone + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.256 fluoren-9-ol dehydrogenase
–
–
MK
L-alpha-glycerophosphate + NADP+ <=> dihydroxyacetone_phosphate + NADPH + H+ 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.261 sn-glycerol-1-phosphate dehydrogenase
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+)
1.1.1.94 glycerol-3-phosphate dehydrogenase [NAD(P)+]
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
BMK
1,5-anhydro-D-glucitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+ 1.1.1.263 1,5-anhydro-D-fructose reductase
–
nitrite + H2O + NADP+ <=> H+ + nitrate + NADPH 1.7.1.1 nitrate reductase (NADH)
1.7.1.2 nitrate reductase [NAD(P)H]
1.7.1.3 nitrate reductase (NADPH)
–
–
–
MK
L-Idonate + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+ 1.1.1.264 L-idonate 5-dehydrogenase
–
BM
3-methyl-1-butanol + NADP+ <=> Isovaleraldehyde + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
dTDP-alpha-D-fucopyranose + NADP+ <=> dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ 1.1.1.266 dTDP-4-dehydro-6-deoxyglucose reductase
1.1.1.B28
–
–
BMK
L-homoserine + NADP+ <=> L-aspartate_4-semialdehyde + NADPH + H+ 1.1.1.3 homoserine dehydrogenase
–
BMK
NO + O2 + NADPH <=> nitrate + NADP+ + H+ 1.14.12.17 nitric oxide dioxygenase
–
albendazole + O2 + NADPH + H+ <=> albendazole_S-oxide + H2O + NADP+ 1.14.13.32 albendazole monooxygenase
–
NADP+ + H+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> oxidized_ferredoxin + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.3 ferredoxin---NAD+ reductase
1.18.1.6 adrenodoxin-NADP+ reductase
–
–
–
M
xylitol + NADP+ <=> L-xylulose + NADPH + H+ 1.1.1.10 L-xylulose reductase
1.1.1.21 aldose reductase
1.1.1.B64
–
–
–
MK
(3R)-3-hydroxyacyl-[acyl-carrier_protein] + NADP+ <=> 3-oxoacyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
–
BMK
1-palmitoyl-sn-glycerol_3-phosphate + NADP+ <=> Palmitoyldihydroxyacetone_phosphate + NADPH + H+ 1.1.1.101 acylglycerone-phosphate reductase
–
sphinganine + NADP+ <=> 3-dehydrosphinganine + NADPH + H+ 1.1.1.102 3-dehydrosphinganine reductase
–
BMK
3-(imidazol-5-yl)lactate + NADP+ <=> 3-(1H-imidazol-4-yl)-2-oxopropanoate + NADPH + H+ 1.1.1.111 3-(imidazol-5-yl)lactate dehydrogenase
–
BM
1-Indanol + NADP+ <=> 1-Indanone + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.218 morphine 6-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
–
–
D-glucose + NADP+ <=> D-glucono-1,5-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
BMK
2-dehydro-3-deoxy-D-gluconate + NADP+ <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H+ 1.1.1.126 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
–
M
3-dehydro-L-gulonate + NADP+ <=> (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NADPH + H+ 1.1.1.130 3-dehydro-L-gulonate 2-dehydrogenase
–
K
NADP+ + D-mannonate <=> D-mannuronic_acid + NADPH + H+ 1.1.1.131 mannuronate reductase
–
dTDP-L-rhamnose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ 1.1.1.133 dTDP-4-dehydrorhamnose reductase
–
BMK
GDP-6-deoxy-D-talose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ 1.1.1.135 GDP-6-deoxy-D-talose 4-dehydrogenase
1.1.1.187 GDP-4-dehydro-D-rhamnose reductase
–
–
MK
D-ribitol_5-phosphate + NADP+ <=> D-ribulose_5-phosphate + NADPH + H+ 1.1.1.137 ribitol-5-phosphate 2-dehydrogenase
1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+)
–
–
MK
pinitol + NADP+ <=> 5D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + NADPH + H+ 1.1.1.142 D-pinitol dehydrogenase
–
M
an_11beta-hydroxysteroid + NADP+ <=> an_11-oxosteroid + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
NADP+ + 16alpha-hydroxysteroid <=> NADPH + a_16-oxosteroid + H+ 1.1.1.147 16alpha-hydroxysteroid dehydrogenase
–
NADP+ + 17alpha-estradiol <=> NADPH + estrone + H+ 1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
K
17alpha,20alpha-dihydroxypregn-4-en-3-one + NADP+ <=> 17alpha-hydroxyprogesterone + NADPH + H+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
K
pregnan-21-ol + NADP+ <=> pregnan-21-al + NADPH + H+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
dihydrobiopterin + NADP+ <=> sepiapterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
–
–
–
K
(S)-ureidoglycolate + NADP+ <=> Oxalureate + NADPH + H+ 1.1.1.154 ureidoglycolate dehydrogenase
–
MK
NADP+ + glycerol <=> H+ + dihydroxyacetone + NADPH 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.10 L-xylulose reductase
1.1.1.142 D-pinitol dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.72 glycerol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
MK
(S)-3-hydroxybutyryl-CoA + NADP+ <=> acetoacetyl-CoA + NADPH + H+ 1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
–
–
K
NADP+ + UDP-N-acetylmuramate <=> H+ + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine 1.3.1.98 UDP-N-acetylmuramate dehydrogenase
–
BMK
D-threitol + NADP+ <=> D-erythrulose + NADPH + H+ 1.1.1.162 erythrulose reductase
–
(R)-pantoate + NADP+ <=> H+ + ketopantoate + NADPH 1.1.1.169 2-dehydropantoate 2-reductase
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
BMK
3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADP+ <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + CO2 + NADPH 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
sn-glycerol_3-phosphate + NADP+ <=> D-glyceraldehyde_3-phosphate + NADPH + H+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.177 glycerol-3-phosphate 1-dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
B
D-xylose + NADP+ <=> D-xylono-1,5-lactone + NADPH + H+ 1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.B35
–
–
–
–
–
–
BMK
geraniol + NADP+ <=> citral + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.324 8-hydroxygeraniol dehydrogenase
1.1.1.90 aryl-alcohol dehydrogenase
–
–
–
–
–
–
MK
an_L-glycol + NADP+ <=> A_2-hydroxycarbonyl_compound + NADPH + H+ 1.1.1.185 L-glycol dehydrogenase
–
dTDP-galactose + H2O + NADP+ <=> dTDP-D-galacturonate + NADPH + H+ 1.1.1.186 dTDP-galactose 6-dehydrogenase
–
tryptophol + NADP+ <=> H+ + NADPH + Indole-3-acetaldehyde 1.1.1
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
–
BMK
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NADP+ <=> 5-amino-6-(5-phospho-D-ribosylamino)uracil + NADPH + H+ 1.1.1.193 5-amino-6-(5-phosphoribosylamino)uracil reductase
–
BMK
an_alcohol + NADP+ <=> an_aldehyde + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.263 1,5-anhydro-D-fructose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.4 (R,R)-butanediol dehydrogenase
1.1.1.61 4-hydroxybutyrate dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.80 isopropanol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
K
L-gulono-1,4-lactone + NADP+ <=> D-glucuronolactone + NADPH + H+ 1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.20 glucuronolactone reductase
1.1.1.21 aldose reductase
–
–
–
–
K
a_7beta-hydroxysteroid + NADP+ <=> a_7-oxosteroid + NADPH + H+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
androsterone + NADP+ <=> 5alpha-androstane-3,17-dione + NADPH + H+ 1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
MK
alditol + NADP+ <=> aldose + NADPH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.10 L-xylulose reductase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.307 D-xylose reductase
1.1.1.365 D-galacturonate reductase
1.1.1.372 D/L-glyceraldehyde reductase
1.1.1.6 glycerol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
BMK
5alpha-Androstane-3beta,17beta-diol + NADP+ <=> 5alpha-dihydrotestosterone + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
–
–
–
M
D-gluconate + NADP+ <=> 2-dehydro-D-gluconate + NADPH + H+ 1.1.1.215 gluconate 2-dehydrogenase
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
1.1.1.43 phosphogluconate 2-dehydrogenase
–
–
–
MK
NADP+ + benzyl_(2R,3S)-2-methyl-3-hydroxy-butanoate <=> H+ + NADPH + benzyl_2-methyl-3-oxobutanoate 1.1.1.217 benzyl-2-methyl-hydroxybutyrate dehydrogenase
1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
–
–
NADP+ + morphine <=> NADPH + morphinone + H+ 1.1.1.218 morphine 6-dehydrogenase
1.1.1.247 codeinone reductase (NADPH)
–
–
MK
(R)-3-(4-hydroxyphenyl)lactate + NADP+ <=> 4-hydroxyphenylpyruvate + NADPH + H+ 1.1.1.110 aromatic 2-oxoacid reductase
1.1.1.237 hydroxyphenylpyruvate reductase
–
–
MK
NADP+ + Chlordecone_alcohol <=> H+ + Chlordecone + NADPH 1.1.1.225 chlordecone reductase
–
3alpha-Hydroxyglycyrrhetic_acid + NADP+ <=> 3,11-dioxoolean-12-en-30-oic_acid + NADPH + H+ 1.1.1.230 3alpha-hydroxyglycyrrhetinate dehydrogenase
–
NADP+ + (15S)-hydroxyeicosatetraenoic_acid <=> NADPH + 15-Oxo-5,8,11-cis-13-trans-eicosatetraenoate + H+ 1.1.1.232 15-hydroxyicosatetraenoate dehydrogenase
–
BK
NADP+ + (2S)-Flavan-4-ol <=> H+ + NADPH + (2S)-flavanone 1.1.1.234 flavanone 4-reductase
–
coformycin + NADP+ <=> 8-Ketocoformycin + NADPH + H+ 1.1.1.235 8-oxocoformycin reductase
–
3alpha,7alpha,12beta-trihydroxy-5beta-cholanoate + NADP+ <=> 12-ketochenodeoxycholic_acid + NADPH + H+ 1.1.1.238 12beta-hydroxysteroid dehydrogenase
–
M
(-)-trans-carveol + NADP+ <=> (-)-Carvone + NADPH + H+ 1.1.1.243 carveol dehydrogenase
1.3.1.102 2-alkenal reductase (NADP+)
–
–
MK
shikimate + NADP+ <=> 3-dehydroshikimate + NADPH + H+ 1.1.1.24 quinate dehydrogenase
1.1.1.25 shikimate dehydrogenase
1.1.1.282 quinate/shikimate dehydrogenase
–
–
–
BMK
2-C-methyl-D-erythritol_4-phosphate + NADP+ <=> 1-deoxy-D-xylulose_5-phosphate + NADPH + H+ 1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase
–
BMK
a_3beta-hydroxysteroid + NADP+ <=> 3-keto_steroid + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
NADP+ + CoA + (R)-mevalonate <=> H+ + NADPH + (S)-3-hydroxy-3-methylglutaryl-CoA 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)
1.1.1.88 hydroxymethylglutaryl-CoA reductase
1.1.1.B38
–
–
–
BMK
(S)-malate + NADP+ <=> pyruvate + CO2 + NADPH 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.39 malate dehydrogenase (decarboxylating)
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.85 3-isopropylmalate dehydrogenase
–
–
–
–
BMK
isocitrate + NADP+ <=> 2-oxoglutarate + CO2 + NADPH 1.1.1.286 isocitrate---homoisocitrate dehydrogenase
1.1.1.41 isocitrate dehydrogenase (NAD+)
1.1.1.42 isocitrate dehydrogenase (NADP+)
–
–
–
BMK
6-phosphogluconate + NADP+ <=> 6-phospho-2-dehydro-D-gluconate + NADPH + H+ 1.1.1.43 phosphogluconate 2-dehydrogenase
–
MK
6-phosphogluconate + NADP+ <=> D-ribulose_5-phosphate + CO2 + NADPH 1.1.1.351 phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
–
–
BMK
D-glucose_6-phosphate + NADP+ <=> 6-phospho-D-glucono-1,5-lactone + NADPH + H+ 1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+]
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
–
BM
testosterone + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
–
BMK
allyl_alcohol + NADP+ <=> acrolein + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.54 allyl-alcohol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
M
D-glycerate + NADP+ <=> tartronate_semialdehyde + NADPH + H+ 1.1.1.60 2-hydroxy-3-oxopropionate reductase
–
BMK
17beta-estradiol + NADP+ <=> estrone + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
–
–
–
MK
NADP+ + pyridoxine <=> H+ + NADPH + pyridoxal 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.65 pyridoxine 4-dehydrogenase
–
–
MK
glycolate + NADP+ <=> glyoxylate + NADPH + H+ 1.1.1.21 aldose reductase
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.237 hydroxyphenylpyruvate reductase
1.1.1.26 glyoxylate reductase
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.92 oxaloglycolate reductase (decarboxylating)
–
–
–
–
–
–
–
BK
2-propanol + NADP+ <=> acetone + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.4 (R,R)-butanediol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.80 isopropanol dehydrogenase (NADP+)
1.1.1.B4
–
–
–
–
–
–
–
–
BMK
D-glycerate + NADP+ <=> Hydroxypyruvate + NADPH + H+ 1.1.1
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.27 L-lactate dehydrogenase
1.1.1.29 glycerate dehydrogenase
1.1.1.60 2-hydroxy-3-oxopropionate reductase
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.86 ketol-acid reductoisomerase (NADP+)
1.1.1.92 oxaloglycolate reductase (decarboxylating)
–
–
–
–
–
–
–
–
–
BMK
(S)-malate + NADP+ <=> H+ + NADPH + oxaloacetate 1.1.1.299 malate dehydrogenase [NAD(P)+]
1.1.1.37 malate dehydrogenase
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.82 malate dehydrogenase (NADP+)
–
–
–
–
–
–
BMK
NADP+ + D-glycerate + CO2 <=> NADPH + Oxaloglycolate + H+ 1.1.1.92 oxaloglycolate reductase (decarboxylating)
–
K
3-Hydroxybenzyl_alcohol + NADP+ <=> 3-Hydroxybenzaldehyde + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
K
succinate_semialdehyde + NADP+ + H2O <=> NADPH + succinate + H+ 1.1.1.21 aldose reductase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
–
–
BMK
malonate_semialdehyde + CoA + NADP+ <=> acetyl-CoA + CO2 + NADPH 1.2.1
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
–
–
MK
2,5-dioxopentanoate + H2O + NADP+ <=> 2-oxoglutarate + NADPH + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
–
–
–
–
BMK
AMP + diphosphate + NADP+ + benzaldehyde <=> ATP + NADPH + aromatic_carboxylate + H+ 1.2.1.30 carboxylate reductase (NADP+)
–
(S)-2-amino-6-oxohexanoate + NADP+ + H2O <=> L-2-aminoadipate + NADPH + H+ 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
–
BMK
formate + NADP+ <=> CO2 + NADPH 1.17.1.10 formate dehydrogenase (NADP+)
1.17.1.9 formate dehydrogenase
–
–
BMK
cinnamaldehyde + CoA + NADP+ <=> cinnamoyl-CoA + NADPH + H+ 1.2.1.44 cinnamoyl-CoA reductase
–
K
4-carboxy-2-hydroxy-cis,cis-muconate_6-semialdehyde + NADP+ <=> 2-Pyrone-4,6-dicarboxylate + NADPH + H+ 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
–
MK
2-Oxoaldehydes + H2O + NADP+ <=> a_2-oxo_carboxylate + NADPH + H+ 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
pyruvate + CoA + NADP+ <=> acetyl-CoA + CO2 + NADPH 1.2.1.51 pyruvate dehydrogenase (NADP+)
–
BM
2-oxoglutarate + CoA + NADP+ <=> succinyl-CoA + CO2 + NADPH 1.2.1.52 oxoglutarate dehydrogenase (NADP+)
–
6-oxohexanoate + H2O + NADP+ <=> H+ + adipate + NADPH 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.63 6-oxohexanoate dehydrogenase
–
–
BMK
coniferyl_aldehyde + NADP+ + H2O <=> ferulic_acid + NADPH + H+ 1.2.1.68 coniferyl-aldehyde dehydrogenase
–
MK
benzaldehyde + H2O + NADP+ <=> benzoate + NADPH + H+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.28 benzaldehyde dehydrogenase (NAD+)
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
MK
D-glyceraldehyde_3-phosphate + NADP+ + H2O <=> H+ + 3-phospho-D-glycerate + NADPH 1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]
–
–
–
MK
dihydrophloroglucinol + NADP+ <=> H+ + phloroglucinol + NADPH 1.3.1.57 phloroglucinol reductase
–
BMK
4-chlorobenzoyl-CoA + Cl- + NADP+ <=> 2,4-dichlorobenzoyl-CoA + NADPH 1.21.1.2 2,4-dichlorobenzoyl-CoA reductase
–
K
NADP+ + cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate <=> CO2 + NADPH + 4-methylcatechol 1.3.1.67 cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
–
K
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ 1.3.1.70 Delta14-sterol reductase
–
BMK
5alpha-Cholest-7-en-3beta-ol + NADP+ <=> 5alpha-cholesta-7,24-dien-3beta-ol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
BMK
oxidized_hemoprotein + NADPH + H+ <=> oxidized_hemoprotein + NADP+ 1.6.2.4 NADPH---hemoprotein reductase
–
mycothiol + NADP+ <=> mycothione + NADPH + H+ 1.8.1.15 mycothione reductase
–
M
NADP+ + acetoacetate + coenzyme_M <=> 2-oxopropyl-CoM + NADPH + CO2 1.8.1.5 2-oxopropyl-CoM reductase (carboxylating)
–
M
4-hydroxyphenylacetate + O2 + NADPH + H+ <=> homogentisate + H2O + NADP+ 1.14.13.18 4-hydroxyphenylacetate 1-monooxygenase
–
K
(R)-pantolactone + NADP+ <=> ketopantoyl_lactone + NADPH + H+ 1.1.1.168 2-dehydropantolactone reductase (Re-specific)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.214 2-dehydropantolactone reductase (Si-specific)
1.1.1.358 2-dehydropantolactone reductase
1.1.1.B51
–
–
–
–
–
M
cholic_acid + NADP+ <=> H+ + NADPH + 12-ketochenodeoxycholic_acid 1.1.1.176 12alpha-hydroxysteroid dehydrogenase
–
M
cinnamyl_alcohol + NADP+ <=> cinnamaldehyde + NADPH + H+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.54 allyl-alcohol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
Prostaglandin_D2 + NADP+ <=> (5Z,13E)-9alpha-Hydroxy-11,15-dioxoprosta-5,13-dienoate + NADPH + H+ 1.1.1.189 prostaglandin-E2 9-reductase
1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
–
–
prostaglandin_E1 + NADP+ <=> 15-dehydro-prostaglandin_E1 + NADPH + H+ 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
–
D-sorbitol_6-phosphate + NADP+ <=> D-glucose_6-phosphate + NADPH + H+ 1.1.1.200 aldose-6-phosphate reductase (NADPH)
–
M
Tropine + NADP+ <=> tropinone + NADPH + H+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
1.1.1.334 methylecgonone reductase
–
–
–
MK
NADP+ + (-)-menthol <=> H+ + (-)-menthone + NADPH 1.1.1.207 (-)-menthol dehydrogenase
–
MK
NADP+ + (+)-neomenthol <=> H+ + NADPH + (-)-menthone 1.1.1.208 (+)-neomenthol dehydrogenase
–
MK
(2E,6E)-farnesol + NADP+ <=> (2E,6E)-farnesal + NADPH + H+ 1.1.1.21 aldose reductase
1.1.1.216 farnesol dehydrogenase (NADP+)
–
–
MK
(2R,3S,4S)-leucoanthocyanidin + NADP+ <=> (2R,3R)-dihydroflavonol + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
NADP+ + D-mannitol_1-phosphate <=> D-mannose_6-phosphate + NADPH + H+ 1.1.1.224 mannose-6-phosphate 6-reductase
–
M
NADP+ + prostaglandin_I2 <=> H+ + NADPH + (5Z,13E)-6,9alpha-epoxy-11alpha-hydroxy-15-oxoprosta-5,13-dienoate 1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
–
–
N,N-Dimethylaniline + O2 + NADPH + H+ <=> N,N-Dimethylaniline_N-oxide + H2O + NADP+ 1.14.13.8 flavin-containing monooxygenase
–
L-kynurenine + O2 + NADPH + H+ <=> L-3-hydroxykynurenine + H2O + NADP+ 1.14.13.9 kynurenine 3-monooxygenase
–
BMK
NADP+ + H2O + malonate_semialdehyde <=> malonate + NADPH + H+ 1.2.1.15 malonate-semialdehyde dehydrogenase
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
BK
an_aldehyde + NADP+ + H2O <=> a_carboxylate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
M
5,6-dihydrouracil + NADP+ <=> Uracil + NADPH + H+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
–
BMK
trans-benzene_dihydrodiol + NADP+ <=> catechol + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
cholesterol + NADP+ <=> 7-dehydrocholesterol + NADPH + H+ 1.3.1.21 7-dehydrocholesterol reductase
–
BMK
GDP-6-deoxy-D-mannose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ 1.1.1.187 GDP-4-dehydro-D-rhamnose reductase
1.1.1.281 GDP-4-dehydro-6-deoxy-D-mannose reductase
–
–
MK
dTDP-6-deoxy-beta-L-talose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ 1.1.1.134 dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+)
1.1.1.344 dTDP-6-deoxy-L-talose 4-dehydrogenase [NAD(P)+]
–
–
K
(+-)-5-[(tert-butylamino)-2''-hydroxypropoxy]-1,2,3,4-tetrahydro-1-naphthol + NADP+ <=> (+-)-5-[(tert-butylamino)-2''-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone + NADPH + H+ 1.1.1.160 dihydrobunolol dehydrogenase
–
prostaglandin_F2alpha + NADP+ <=> Prostaglandin_D2 + NADPH + H+ 1.1.1.188 prostaglandin-F synthase
–
prostaglandin_F2alpha + NADP+ <=> NADPH + prostaglandin_E2 + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.189 prostaglandin-E2 9-reductase
–
–
BK
coniferyl_alcohol + NADP+ <=> coniferyl_aldehyde + NADPH + H+ 1.1.1.194 coniferyl-alcohol dehydrogenase
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
BMK
NADP+ + Diethyl_(2R,3R)-2-methyl-3-hydroxysuccinate <=> H+ + NADPH + Diethyl_2-methyl-3-oxosuccinate 1.1.1.229 diethyl 2-methyl-3-oxosuccinate reductase
–
GDP-L-fucose + NADP+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADPH + H+ 1.1.1.271 GDP-L-fucose synthase
–
K
(R)-2-hydroxyacid + NADP+ <=> a_2-oxo_carboxylate + NADPH + H+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
–
D-gluconate + NADP+ <=> 5-Dehydro-D-gluconate + NADPH + H+ 1.1.1
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.69 gluconate 5-dehydrogenase
–
–
–
BM
benzyl_alcohol + NADP+ <=> benzaldehyde + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
4-hydroxybenzoate + NADPH + O2 + H+ <=> 3,4-dihydroxybenzoate + NADP+ + H2O 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
1.14.13.33 4-hydroxybenzoate 3-monooxygenase [NAD(P)H]
–
–
BMK
L-aspartate_4-semialdehyde + phosphate + NADP+ <=> L-4-aspartyl_phosphate + NADPH + H+ 1.2.1.11 aspartate-semialdehyde dehydrogenase
–
BMK
glyoxylate + CoA + NADP+ <=> oxalyl-CoA + NADPH + H+ 1.2.1.17 glyoxylate dehydrogenase (acylating)
–
MK
N-acetyl-L-glutamate_5-semialdehyde + NADP+ + phosphate <=> H+ + N-acetyl-L-glutamyl_5-phosphate + NADPH 1.2.1.38 N-acetyl-gamma-glutamyl-phosphate reductase
–
BMK
L-glutamate_5-semialdehyde + phosphate + NADP+ <=> L-5-glutamyl_phosphate + NADPH + H+ 1.2.1.41 glutamate-5-semialdehyde dehydrogenase
–
BMK
prephenate + NADP+ <=> 4-hydroxyphenylpyruvate + CO2 + NADPH 1.3.1.12 prephenate dehydrogenase
1.3.1.13 prephenate dehydrogenase (NADP+)
1.3.1.78 arogenate dehydrogenase (NADP+)
1.3.1.79 arogenate dehydrogenase [NAD(P)+]
–
–
–
–
K
L-dihydroorotate + NADP+ <=> H+ + Orotate + NADPH 1.3.1.15 dihydroorotate dehydrogenase (NADP+)
–
3-nitropropionate + NADP+ <=> H+ + 3-Nitroacrylate + NADPH 1.3.1.16 beta-nitroacrylate reductase
–
3-methyloxindole + NADP+ <=> 3-methyleneoxindole + NADPH + H+ 1.3.1.17 3-methyleneoxindole reductase
–
5beta-cholestan-3-one + NADP+ <=> H+ + cholest-4-en-3-one + NADPH 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NADP+ + H2O <=> (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADPH + H+ 1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase
–
BMK
hexadecanal + NADP+ <=> 2-trans-hexadecenal + NADPH + H+ 1.3.1.27 2-hexadecenal reductase
–
BM
17alpha,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ <=> H+ + cortisone + NADPH 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
K
3-oxoadipate + NADP+ <=> maleylacetate + NADPH + H+ 1.3.1.32 maleylacetate reductase
–
BMK
trans-2-enoyl-CoA + NADP+ <=> trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
–
acyl-CoA + NADP+ <=> cis-2,3-dehydroacyl-CoA + NADPH + H+ 1.3.1.37 cis-2-enoyl-CoA reductase (NADPH)
–
acyl-CoA + NADP+ <=> trans-2-enoyl-CoA + NADPH + H+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.44 trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
–
K
2,6-Dioxo-6-phenylhexanoate + NADP+ <=> 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + NADPH + H+ 1.3.1.40 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
–
NADP+ + 3-oxo-2((2Z)-pentenyl)-cyclopentane-1-octanoic_acid <=> H+ + NADPH + 12-oxo-phytodienoic_acid 1.3.1.42 12-oxophytodienoate reductase
–
MK
vestitone + NADP+ <=> 2'-hydroxyformononetin + NADPH + H+ 1.3.1.45 2'-hydroxyisoflavone reductase
1.3.1.51 2'-hydroxydaidzein reductase
–
–
MK
NADP+ + dihydrobiochanin-A <=> NADPH + Biochanin_A + H+ 1.3.1.46 biochanin-A reductase
–
K
NADP+ + 1,2-dihydrosantonin <=> NADPH + alpha-santonin + H+ 1.3.1.47 alpha-santonin 1,2-reductase
–
23,24-dihydrocucurbitacin_B + NADP+ <=> cucurbitacin_B + NADPH + H+ 1.3.1.5 cucurbitacin Delta23-reductase
–
ergosterol + NADP+ <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADPH + H+ 1.3.1.71 Delta24(241)-sterol reductase
1.3.1.72 Delta24-sterol reductase
–
–
MK
2,4-Diaminopentanoate + H2O + NADP+ <=> (2R)-2-amino-4-oxopentanoate + NH3 + NADPH + H+ 1.4.1.12 2,4-diaminopentanoate dehydrogenase
–
BMK
L-glutamate + NADP+ <=> H+ + L-glutamine + 2-oxoglutarate + NADPH 1.4.1.13 glutamate synthase (NADPH)
1.4.1.B5
–
–
BMK
meso-2,6-diaminoheptanedioate + NADP+ + H2O <=> L-2-amino-6-oxopimelate + NH3 + NADPH + H+ 1.4.1.16 diaminopimelate dehydrogenase
–
BMK
N-Methyl-L-alanine + H2O + NADP+ <=> H+ + methylamine + pyruvate + NADPH 1.4.1.17 N-methylalanine dehydrogenase
1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
–
L-tryptophan + H2O + NADP+ <=> 3-Indole-2-oxopropanoate + NH3 + NADPH + H+ 1.4.1.19 tryptophan dehydrogenase
–
NADP+ + H2O + L-glutamate <=> NADPH + 2-oxoglutarate + NH3 + H+ 1.4.1.13 glutamate synthase (NADPH)
1.4.1.2 glutamate dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
–
–
–
–
BMK
L-valine + H2O + NADP+ <=> 2-oxoisovalerate + NH3 + NADPH + H+ 1.4.1.23 valine dehydrogenase (NAD+)
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
1.4.1.8 valine dehydrogenase (NADP+)
–
–
–
–
L-proline + NADP+ <=> DELTA1-pyrroline-2-carboxylate + NADPH + H+ 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
1.5.1.25 thiomorpholine-carboxylate dehydrogenase
1.5.1.49 1-pyrroline-2-carboxylate reductase [NAD(P)H]
–
–
–
–
BMK
H2O + NADP+ + D-lysopine <=> H+ + NADPH + pyruvate + L-lysine 1.5.1.11 D-octopine dehydrogenase
1.5.1.16 D-lysopine dehydrogenase
–
–
K
L-proline + NADP+ <=> L-pyrroline-5-carboxylate + NADPH + H+ 1.5.1.2 pyrroline-5-carboxylate reductase
–
BMK
L-pipecolic_acid + NADP+ <=> DELTA1-piperideine-2-carboxylate + NADPH + H+ 1.5.1.1 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase [NAD(P)H]
1.5.1.21 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH)
1.5.1.25 thiomorpholine-carboxylate dehydrogenase
1.5.1.49 1-pyrroline-2-carboxylate reductase [NAD(P)H]
–
–
–
–
MK
H2O + NADP+ + N5-(L-1-carboxyethyl)-L-ornithine <=> H+ + NADPH + pyruvate + L-ornithine 1.5.1.24 N5-(carboxyethyl)ornithine synthase
–
FMNH2 + NADP+ <=> FMN + NADPH + H+ 1.18.1.2 ferredoxin---NADP+ reductase
1.5.1
1.5.1.30 flavin reductase (NADPH)
1.5.1.36 flavin reductase (NADH)
1.5.1.38 FMN reductase (NADPH)
1.5.1.39 FMN reductase [NAD(P)H]
1.5.1.41 riboflavin reductase [NAD(P)H]
1.5.1.42 FMN reductase (NADH)
1.5.1.45 FAD reductase [NAD(P)H]
–
–
–
–
–
–
–
–
–
BMK
tetrahydrofolate + NADP+ <=> 7,8-dihydrofolate + NADPH + H+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase
1.5.1.50 dihydromonapterin reductase
–
–
–
–
BMK
reduced_riboflavin + NADP+ <=> H+ + riboflavin + NADPH 1.5.1.30 flavin reductase (NADPH)
1.5.1.38 FMN reductase (NADPH)
1.5.1.41 riboflavin reductase [NAD(P)H]
–
–
–
BK
5,10-methylenetetrahydrofolate + NADP+ <=> 5,10-methenyltetrahydrofolate + NADPH 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
–
–
BMK
saccharopine + H2O + NADP+ <=> L-lysine + 2-oxoglutarate + NADPH + H+ 1.5.1.8 saccharopine dehydrogenase (NADP+, L-lysine-forming)
–
BMK
NAD+ + NADPH <=> NADH + NADP+ 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)
1.6.1.3 NAD(P)+ transhydrogenase
7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
–
–
–
–
BMK
acceptor + NADPH + H+ <=> reduced_acceptor + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.99.1 NADPH dehydrogenase
–
–
–
NH3 + NADP+ + H2O <=> nitrite + NADPH + H+ 1.7.1.4 nitrite reductase [NAD(P)H]
1.7.7.1 ferredoxin---nitrite reductase
1.8.1.2 assimilatory sulfite reductase (NADPH)
–
–
–
MK
4-(hydroxyamino)quinoline_N-oxide + NADP+ + H2O <=> 4-Nitroquinoline_N-oxide + NADPH + H+ 1.7.1.9 nitroquinoline-N-oxide reductase
–
gamma-Glu-L-Cys + NADP+ <=> H+ + bis-gamma-glutamylcystine + NADPH 1.8.1.13 bis-gamma-glutamylcystine reductase
–
BK
Sulfide + NADP+ + H2O <=> sulfite + NADPH + H+ 1.8.1.2 assimilatory sulfite reductase (NADPH)
–
BMK
CoA + NADP+ <=> CoA-disulfide + NADPH + H+ 1.8.1.10 CoA-glutathione reductase
1.8.1.14 CoA-disulfide reductase
1.8.4.2 protein-disulfide reductase (glutathione)
–
–
–
B
IMP + NH3 + NADP+ <=> GMP + NADPH + H+ 1.7.1.7 GMP reductase
–
BK
N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ <=> 4-(dimethylamino)azobenzene + NADPH + H+ 1.7.1.6 azobenzene reductase
–
H2O + NADP+ + 2-acetylaminofluorene <=> NADPH + N-Hydroxy-2-acetylaminofluorene + H+ 1.7.1.12 N-hydroxy-2-acetamidofluorene reductase
–
4-(dimethylamino)azobenzene + NADP+ + H2O <=> 4-(dimethylamino)phenylazoxybenzene + NADPH + H+ 1.7.1.11 4-(dimethylamino)phenylazoxybenzene reductase
–
NADPH + ferricytochrome_b5 <=> NADP+ + ferricytochrome_b5 + H+ 1.18.1.2 ferredoxin---NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
1.6.2.2 cytochrome-b5 reductase
1.6.2.4 NADPH---hemoprotein reductase
1.6.2.5 NADPH---cytochrome-c2 reductase
1.6.2.6 leghemoglobin reductase
–
–
–
–
–
–
glutathione + NADP+ <=> GSSG + NADPH + H+ 1.8.1.7 glutathione-disulfide reductase
1.8.1.9 thioredoxin-disulfide reductase
1.8.1.B1
1.8.4.2 protein-disulfide reductase (glutathione)
–
–
–
–
BMK
trypanothione + NADP+ <=> trypanothione_disulfide + NADPH + H+ 1.8.1.12 trypanothione-disulfide reductase
–
BK
glutathione + CoA + NADP+ <=> H+ + CoA-glutathione + NADPH 1.8.1.10 CoA-glutathione reductase
1.8.1.14 CoA-disulfide reductase
1.8.4.2 protein-disulfide reductase (glutathione)
–
–
–
Questin + O2 + NADPH <=> demethylsulochrin + NADP+ 1.14.13.43 questin monooxygenase
–
M
taxifolin + O2 + NADPH + H+ <=> 2,3-dihydrogossypetin + H2O + NADP+ 1.14.13.19 taxifolin 8-monooxygenase
–
(+)-trans-Acenaphthene-1,2-diol + NADP+ <=> acenaphthenequinone + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase
–
–
1,2-dihydrovomilenine + NADP+ <=> Vomilenine + NADPH + H+ 1.5.1.32 vomilenine reductase
–
MK
saccharopine + NADP+ + H2O <=> H+ + L-glutamate + (S)-2-amino-6-oxohexanoate + NADPH 1.5.1.10 saccharopine dehydrogenase (NADP+, L-glutamate-forming)
–
BMK
NADP+ + bilirubin <=> Biliverdin + NADPH + H+ 1.3.1.24 biliverdin reductase
–
BMK
reduced_rubredoxin + NADP+ + H+ <=> oxidized_rubredoxin + NADPH 1.18.1.1 rubredoxin---NAD+ reductase
1.18.1.4 rubredoxin---NAD(P)+ reductase
–
–
BK
CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADP+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ 1.17.1.1 CDP-4-dehydro-6-deoxyglucose reductase
–
MK
Hg + NADP+ + H+ <=> Hg2+ + NADPH 1.16.1.1 mercury(II) reductase
–
BM
phenol + O2 + NADPH + H+ <=> catechol + H2O + NADP+ 1.14.13.7 phenol 2-monooxygenase (NADPH)
1.14.14.20 phenol 2-monooxygenase (FADH2)
–
–
BMK
6-Oxocineole + O2 + NADPH + H+ <=> 1,6,6-Trimethyl-2,7-dioxa(3,2,2)bicyclononan-3-one + H2O + NADP+ 1.14.13.51 6-oxocineole dehydrogenase
–
MK
Pentachlorophenol + O2 + NADPH + H+ <=> tetrafluoro-1,4-benzoquinone + Cl- + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
MK
2-aminobenzoyl-CoA + O2 + NADPH + H+ <=> 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + NADP+ 1.14.13.40 anthraniloyl-CoA monooxygenase
–
MK
anhydrotetracycline + O2 + NADPH + H+ <=> 5a,11a-dehydrotetracycline + H2O + NADP+ 1.14.13.38 anhydrotetracycline 6-monooxygenase
–
MK
H+ + anthranilate + O2 + NADPH <=> NH3 + NADP+ + 2,3-Dihydroxybenzoate 1.14.13.35 anthranilate 3-monooxygenase (deaminating)
–
K
leukotriene_E4 + O2 + NADPH + H+ <=> 20-hydroxy-leukotriene_E4 + H2O + NADP+ 1.14.13.34 leukotriene-E4 20-monooxygenase
–
K
2-Nitrophenol + O2 + NADPH + H+ <=> catechol + nitrite + H2O + NADP+ 1.14.13.31 2-nitrophenol 2-monooxygenase
–
M
4-Aminobenzoic_acid + O2 + NADPH + H+ <=> 4-Aminophenol + CO2 + H2O + NADP+ 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
K
methane + NADPH + O2 + H+ <=> methanol + NADP+ + H2O 1.14.13.25 methane monooxygenase (soluble)
1.14.15.3 alkane 1-monooxygenase
–
–
M
3-hydroxybenzoate + O2 + NADPH + H+ <=> 3,4-dihydroxybenzoate + H2O + NADP+ 1.14.13.2 4-hydroxybenzoate 3-monooxygenase
1.14.13.23 3-hydroxybenzoate 4-monooxygenase
–
–
MK
cyclohexanone + NADPH + H+ + O2 <=> epsilon-caprolactone + NADP+ + H2O 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
–
BMK
2,4-Dichlorophenol + O2 + NADPH + H+ <=> 3,5-dichlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
–
MK
Cyclopentanone + O2 + NADPH + H+ <=> delta-valerolactone + H2O + NADP+ 1.14.13.16 cyclopentanone monooxygenase
1.14.13.22 cyclohexanone monooxygenase
–
–
H+ + Cinnamic_acid + O2 + NADPH <=> H2O + NADP+ + coumaric_acid 1.14.13.14 trans-cinnamate 2-monooxygenase
1.14.14.91 trans-cinnamate 4-monooxygenase
–
–
MK
nicotinate + O2 + NADPH <=> 2-(Hydroxymethyl)-3-(acetamidomethylene)succinate + NADP+ 1.14.13.241 5-pyridoxate monooxygenase
–
K
anthranilate + O2 + NADPH + H+ <=> catechol + CO2 + NH3 + NADP+ 1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
–
MK
NADP+ + H2 <=> NADPH + H+ 1.12.1.2 hydrogen dehydrogenase
1.12.1.3 hydrogen dehydrogenase (NADP+)
1.12.1.5 hydrogen dehydrogenase [NAD(P)+]
–
–
–
BM
H+ + H2O2 + NADPH <=> H2O + NADP+ 1.11.1.1 NADH peroxidase
1.11.1.11 L-ascorbate peroxidase
1.11.1.2 NADPH peroxidase
1.11.1.24 thioredoxin-dependent peroxiredoxin
1.11.1.27 glutathione-dependent peroxiredoxin
1.11.1.5 cytochrome-c peroxidase
1.11.1.6 catalase
1.11.1.7 peroxidase
–
–
–
–
–
–
–
–
10-deoxysarpagine + NADP+ <=> gardneral + NADPH + H+ 1.1.1.273 vellosimine dehydrogenase
–
MK
2-dehydro-D-gluconate + NADP+ <=> H+ + NADPH + 2,5-didehydro-D-gluconate 1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
BM
(R)-canadine + NADP+ <=> Berberine + NADPH + H+ 1.5.1.31 berberine reductase
–
K
NADP+ + 1,4-Thiomorpholine_3-carboxylic_acid <=> NADPH + S-Aminoethylcysteine_ketimine + H+ 1.5.1.25 thiomorpholine-carboxylate dehydrogenase
–
17-O-acetylnorajmaline + NADP+ <=> 1,2-dihydrovomilenine + NADPH + H+ 1.3.1.73 1,2-dihydrovomilenine reductase
–
MK
NADP+ + dihydrozeatin <=> H+ + trans-zeatin + NADPH 1.3.1.69 zeatin reductase
–
K
tetrahydrobiopterin + NADP+ <=> biopterin + NADPH + H+ 1.5.1.33 pteridine reductase
–
K
tetrahydropteridine + NADP+ <=> dihydropteridine + NADPH + H+ 1.5.1.34 6,7-dihydropteridine reductase
–
M
S-adenosyl-L-methionine + palmatine + NADPH <=> S-adenosyl-L-homocysteine + corydaline + NADP+ 2.1.1.147 corydaline synthase
–
K
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 6-Methylsalicylate + CoA + CO2 + NADP+ + H2O 2.3.1.165 6-methylsalicylic-acid synthase
–
MK
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> fatty_acid + CoA + CO2 + NADP+ 2.3.1.38 [acyl-carrier-protein] S-acetyltransferase
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
K
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> stearoyl-CoA + CoA + CO2 + NADP+ 2.3.1.86 fatty-acyl-CoA synthase system
–
K
propionyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 6-Deoxyerythronolide_b + CoA + CO2 + H2O + NADP+ 2.3.1.94 6-deoxyerythronolide-B synthase
–
MK
(2E,6E)-farnesyl_diphosphate + NADPH + H+ <=> squalene + diphosphate + NADP+ 2.5.1.148 lycopaoctaene synthase
2.5.1.21 squalene synthase
–
–
K
magnesium_protoporphyrin_monomethyl_ester + NADPH + H+ + O2 <=> divinyl_protochlorophyllide_a + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
K
catechin + NADP+ + H2O <=> Leucocyanidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
–
MK
5beta-Pregnan-3beta-ol-20-one + NADP+ <=> H+ + 5beta-pregnane-3,20-dione + NADPH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.277 3beta-hydroxy-5beta-steroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
–
–
–
–
M
an_n-alkanal + NADP+ <=> alk-2-enal + NADPH + H+ 1.3.1.102 2-alkenal reductase (NADP+)
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
NADPH + H+ + O2 <=> NADP+ + H2O2 1.6.3.1 NAD(P)H oxidase (H2O2-forming)
1.6.3.3 NADH oxidase (H2O2-forming)
–
–
L-serine + NADP+ <=> aminoacetaldehyde + NADPH + CO2 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
5alpha-pregnane-3beta-ol-20-one + NADP+ <=> H+ + 5alpha-dihydroprogesterone + NADPH 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.278 3beta-hydroxy-5alpha-steroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
–
–
–
–
–
–
–
MK
NADP+ + ethyl_(R)-3-hydroxyhexanoate <=> H+ + NADPH + ethyl_3-oxohexanoate 1.1.1.279 (R)-3-hydroxyacid-ester dehydrogenase
–
NADP+ + ethyl_(S)-3-hydroxyhexanoate <=> H+ + NADPH + ethyl_3-oxohexanoate 1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
1.1.1.283 methylglyoxal reductase (NADPH)
–
–
(R)-2,3-dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Hydroxy-2-methyl-3-oxobutanoate + NADPH + H+ 1.1.1.383 ketol-acid reductoisomerase [NAD(P)+]
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
MK
protochlorophyllide + NADP+ <=> divinyl_protochlorophyllide_a + NADPH + H+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
BK
NAD+ + ATP <=> H+ + NADP+ + ADP 2.7.1.23 NAD+ kinase
–
BMK
nicotinate + H2O + NADP+ <=> 6-Hydroxynicotinate + NADPH + H+ 1.17.1.5 nicotinate dehydrogenase
–
MK
quinate + NADP+ <=> 3-dehydroquinate + NADPH + H+ 1.1.1.24 quinate dehydrogenase
1.1.1.25 shikimate dehydrogenase
1.1.1.282 quinate/shikimate dehydrogenase
–
–
–
MK
4-hydroxyacetophenone + NADPH + O2 + H+ <=> 4-hydroxyphenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
MK
octadecanal + O2 + NADPH + H+ <=> heptadecane + formate + H2O + NADP+ 4.1.99.5 aldehyde oxygenase (deformylating)
–
M
L-aspartate + H2O + NADP+ <=> oxaloacetate + NH3 + NADPH + H+ 1.4.1.2 glutamate dehydrogenase
1.4.1.21 aspartate dehydrogenase
–
–
L-lactaldehyde + NADP+ <=> methylglyoxal + NADPH + H+ 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.78 methylglyoxal reductase (NADH)
1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
BMK
squalene + diphosphate + NADP+ <=> presqualene_diphosphate + NADPH + H+ 1.3.1.96 Botryococcus squalene synthase
1.3.1.97 botryococcene synthase
2.5.1.21 squalene synthase
–
–
–
BMK
senecionine + NADPH + O2 + H+ <=> senecionine_N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
–
MK
S-hydroxymethylglutathione + NADP+ <=> S-formylglutathione + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase
–
–
BM
L-arogenate + NADP+ <=> L-tyrosine + CO2 + NADPH 1.3.1.43 arogenate dehydrogenase
1.3.1.78 arogenate dehydrogenase (NADP+)
1.3.1.79 arogenate dehydrogenase [NAD(P)+]
–
–
–
BMK
2,3,5,6-Tetrachlorophenol + NADPH + O2 <=> tetrachlorohydroquinone + NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
2,3-cis-flavan-3-ol + NADP+ <=> anthocyanidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
M
H+ + 4-coumaroyl-CoA + malonyl-CoA + NADPH <=> isoliquiritigenin + CoA + CO2 + NADP+ + H2O 2.3.1.170 6'-deoxychalcone synthase
–
MK
2''-deoxymugineate + NADP+ <=> 3''''-deamino-3''''-oxonicotianamine + NADPH + H+ 1.1.1.285 3''-deamino-3''-oxonicotianamine reductase
–
M
D-arabitol + NADP+ <=> D-xylulose + NADPH + H+ 1.1.1.14 L-iditol 2-dehydrogenase
1.1.1.287 D-arabinitol dehydrogenase (NADP+)
–
–
K
D-arabitol + NADP+ <=> D-ribulose + NADPH + H+ 1.1.1.287 D-arabinitol dehydrogenase (NADP+)
–
K
chlorophyllide_a + O2 + NADPH + H+ <=> 7-hydroxychlorophyllide_a + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
BMK
chlorophyllide_a + O2 + NADPH + H+ <=> chlorophyllide_b + H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
phenylacetone + NADPH + O2 + H+ <=> Benzyl_acetate + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
pre-queuine_1 + NADP+ <=> 7-cyano-7-carbaguanine + NADPH + H+ 1.7.1.13 preQ1 synthase
–
MK
1,5-anhydro-D-mannitol + NADP+ <=> 1,5-Anhydro-D-fructose + NADPH + H+ 1.1.1.263 1,5-anhydro-D-fructose reductase
1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
–
–
M
3beta-hydroxy-9beta-pimara-7,15-diene-19,6beta-olide + NADP+ <=> momilactone_A + NADPH + H+ 1.1.1.295 momilactone-A synthase
–
MK
(-)-menthone + NADPH + H+ + O2 <=> (4R,7S)-7-isopropyl-4-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
K
isodihydrocarvone + NADPH + H+ + O2 <=> isoprop(en)ylmethyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
1-hydroxymenth-8-en-2-one + NADPH + H+ + O2 <=> 7-hydroxy-4-isopropenyl-7-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(-)-menthone + NADP+ <=> (R)-pulegone + NADPH + H+ 1.3.1.81 (+)-pulegone reductase
–
MK
(+)-isomenthone + NADP+ <=> (R)-pulegone + NADPH + H+ 1.3.1.81 (+)-pulegone reductase
–
MK
(+)-cis-isopulegone + NADP+ <=> (-)-isopiperitenone + NADPH + H+ 1.3.1.82 (-)-isopiperitenone reductase
–
MK
all-trans-retinol + NADP+ <=> all-trans-retinal + NADPH + H+ 1.1.1
1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.300 NADP-retinol dehydrogenase
1.1.1.315 11-cis-retinol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
–
–
–
–
MK
(+)-epi-isozizaene + O2 + NADPH + H+ <=> (5S)-albaflavenol + H2O + NADP+ 1.14.13.106 epi-isozizaene 5-monooxygenase
–
MK
(5S)-albaflavenol + O2 + NADPH + H+ <=> albaflavenone + H2O + NADP+ 1.14.13.106 epi-isozizaene 5-monooxygenase
–
MK
(+)-epi-isozizaene + O2 + NADPH + H+ <=> (5R)-albaflavenol + H2O + NADP+ 1.14.13.106 epi-isozizaene 5-monooxygenase
–
MK
(5R)-albaflavenol + O2 + NADPH + H+ <=> albaflavenone + H2O + NADP+ 1.14.13.106 epi-isozizaene 5-monooxygenase
–
MK
limonene + NADPH + H+ + O2 <=> 1,2-epoxymenth-8-ene + NADP+ + H2O 1.14.13.107 limonene 1,2-monooxygenase
–
phytyl_diphosphate + NADP+ <=> geranylgeranyl_diphosphate + NADPH + H+ 1.3.1.83 geranylgeranyl diphosphate reductase
–
BK
4-hydroxylamino-2,6-dinitrotoluene + H2O + NADP+ <=> 2,4,6-trinitrotoluene + NADPH + H+ 1
1.7.1
1.7.1.B1
1.7.1.B3
–
–
–
–
K
3-hydroxypropionate + NADP+ <=> malonate_semialdehyde + NADPH + H+ 1.1.1
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.276 serine 3-dehydrogenase (NADP+)
1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)
–
–
–
–
BMK
malonate_semialdehyde + CoA + NADP+ <=> malonyl-CoA + NADPH + H+ 1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)
–
–
BMK
succinate_semialdehyde + NADP+ + CoA <=> succinyl-CoA + NADPH + H+ 1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)
1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
–
–
BMK
propionyl-CoA + NADP+ <=> acryloyl-CoA + NADPH + H+ 1.3.1
1.3.1.84 acrylyl-CoA reductase (NADPH)
1.3.1.95 acrylyl-CoA reductase (NADH)
–
–
–
BMK
benzoyl-CoA + NADPH + H+ + O2 <=> 2,3-epoxy-2,3-dihydrobenzoyl-CoA + NADP+ + H2O 1.14.13.208 benzoyl-CoA 2,3-epoxidase
–
MK
2,5-diamino-6-(1-D-ribitylamino)-4(3H)-pyrimidinone_5'-phosphate + NADP+ <=> 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate + NADPH + H+ 1.1.1.302 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
–
K
xylitol + NADP+ <=> D-xylose + NADPH + H+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.188 prostaglandin-F synthase
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.289 sorbose reductase
1.1.1.307 D-xylose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
MK
L-tyrosine + NADP+ + I- <=> 3-iodo-L-tyrosine + NADPH 1.21.1.1 iodotyrosine deiodinase
–
3-iodo-L-tyrosine + I- + NADP+ <=> 3,5-diiodo-L-tyrosine + NADPH + H+ 1.21.1.1 iodotyrosine deiodinase
–
L-ornithine + O2 + NADPH <=> N5-hydroxy-L-ornithine + H2O + NADP+ 1.14.13.195 L-ornithine N5-monooxygenase (NADPH)
1.14.13.196 L-ornithine N5-monooxygenase [NAD(P)H]
–
–
BM
carbazole + O2 + NADPH + H+ <=> 2''-aminobiphenyl-2,3-diol + NADP+ 1.14.12.22 carbazole 1,9a-dioxygenase
–
MK
(2S)-ethylmalonyl-CoA + NADP+ <=> crotonyl-CoA + CO2 + NADPH 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
BMK
butyryl-CoA + NADP+ <=> crotonyl-CoA + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
1.3.1.44 trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
1.3.1.85 crotonyl-CoA carboxylase/reductase
1.3.1.86 crotonyl-CoA reductase
1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
–
–
–
–
–
–
–
–
K
7-methylxanthine + NADPH + O2 + H+ <=> xanthine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
–
BMK
isethionate + NADP+ <=> 2-sulfoacetaldehyde + NADPH + H+ 1.1.1.313 sulfoacetaldehyde reductase
–
MK
2-sulfoacetaldehyde + CoA + NADP+ <=> sulfoacetyl-CoA + NADPH + H+ 1.2.1.81 sulfoacetaldehyde dehydrogenase (acylating)
–
M
N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O <=> L-arginine + 2-oxoglutarate + NADPH + H+ 1.5.1.19 D-nopaline dehydrogenase
–
K
N2O + NADP+ + H2O <=> NO + NADPH + H+ 1.7.1.14 nitric oxide reductase [NAD(P)+, nitrous oxide-forming]
1.7.2.5 nitric oxide reductase (cytochrome c)
–
–
K
gamma-glutamyl-gamma-aminobutyraldehyde + NADP+ + H2O <=> 4-(glutamylamino)_butanoate + NADPH + H+ 1.2.1.99 4-(gamma-glutamylamino)butanal dehydrogenase
–
BMK
5,6-dihydrouracil16_in_tRNA + NADP+ <=> uracil16_in_tRNA + NADPH + H+ 1.3.1.88 tRNA-dihydrouridine16/17 synthase [NAD(P)+]
–
5,6-dihydrouracil17_in_tRNA + NADP+ <=> uracil17_in_tRNA + NADPH + H+ 1.3.1.88 tRNA-dihydrouridine16/17 synthase [NAD(P)+]
–
5,6-dihydrouracil20_in_tRNA + NADP+ <=> uracil20_in_tRNA + NADPH + H+ 1.3.1.91 tRNA-dihydrouridine20 synthase [NAD(P)+]
–
5,6-dihydrouracil47_in_tRNA + NADP+ <=> uracil47_in_tRNA + NADPH + H+ 1.3.1.89 tRNA-dihydrouridine47 synthase [NAD(P)+]
–
5,6-dihydrouracil20a_in_tRNA + NADP+ <=> uracil20a_in_tRNA + NADPH + H+ 1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+]
–
5,6-dihydrouracil20b_in_tRNA + NADP+ <=> uracil20b_in_tRNA + NADPH + H+ 1.3.1.90 tRNA-dihydrouridine20a/20b synthase [NAD(P)+]
–
carboxynorspermidine + NADP+ + H2O <=> L-aspartate_4-semialdehyde + 1,3-diaminopropane + NADPH + H+ 1.4.1.B4
1.5.1.43 carboxynorspermidine synthase
–
–
BMK
reduced_coenzyme_F420 + NADP+ <=> coenzyme_F420 + NADPH + H+ 1.5.1.40 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
–
S-adenosyl-L-methionine + L-tyrosine + NADPH <=> 2-iminoacetate + p-Cresol + 5''-deoxyadenosine + L-methionine + NADP+ + H+ 4.1.99.19 2-iminoacetate synthase
–
BM
progesterone + NADPH + H+ + O2 <=> Testosterone_acetate + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
1.14.99.4 progesterone monooxygenase
–
–
4-androstene-3,17-dione + NADPH + H+ + O2 <=> testololactone + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
1.14.99.12 androst-4-ene-3,17-dione monooxygenase
–
–
17alpha-hydroxyprogesterone + NADPH + O2 <=> 4-androstene-3,17-dione + acetate + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
–
3-oxo-5,6-dehydrosuberyl-CoA_semialdehyde + NADP+ + H2O <=> 3-oxo-5,6-dehydrosuberyl-CoA + NADPH + H+ 1.2.1.91 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase
–
BMK
1-hydroxy-2-naphthoate + NADPH + O2 + H+ <=> 1,2-dihydroxynaphthalene + NADP+ + H2O + CO2 1.14.13.135 1-hydroxy-2-naphthoate hydroxylase
–
erythromycin_D + O2 + NADPH + H+ <=> erythromycin_C + H2O + NADP+ 1.14.13.154 erythromycin 12-hydroxylase
–
MK
raucaffrinoline + NADP+ <=> perakine + NADPH + H+ 1.1.1.317 perakine reductase
–
M
trimethylamine + O2 + NADPH <=> Trimethylamine_N-oxide + H2O + NADP+ 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
MK
phenylacetyl-CoA + O2 + NADPH + H+ <=> 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + NADP+ + H2O 1.14.13.149 phenylacetyl-CoA 1,2-epoxidase
–
BMK
tetrahydrobiopterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
K
eugenol + a_carboxylate + NADP+ <=> a_coniferyl_ester + NADPH 1.1.1.318 eugenol synthase
–
isoeugenol + acetate + NADP+ <=> coniferyl_acetate + NADPH 1.1.1.319 isoeugenol synthase
–
BMK
(S)-benzoin + NADP+ <=> benzil + NADPH + H+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
(R)-benzoin + NADP+ <=> benzil + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.321 benzil reductase [(R)-benzoin forming]
–
–
(+)-thujan-3-ol + NADP+ <=> (+)-thujan-3-one + NADPH + H+ 1.1.1.323 (+)-thujan-3-ol dehydrogenase
–
(6E)-8-hydroxygeraniol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
K
(6E)-8-hydroxygeraniol + NADP+ <=> (6E)-8-hydroxygeranial + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
M
(6E)-8-hydroxygeraniol + NADP+ <=> (6E)-8-oxogeraniol + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
M
(6E)-8-hydroxygeranial + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
M
(6E)-8-oxogeraniol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.1.1.324 8-hydroxygeraniol dehydrogenase
–
M
L-threo-7,8-dihydrobiopterin + NADP+ <=> sepiapterin + NADPH + H+ 1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
–
(+)-sabinene + NADPH + H+ + O2 <=> (+)-cis-Sabinol + NADP+ + H2O 1.14.13.153 (+)-sabinene 3-hydroxylase
–
(+)-epi-isozizaene + NADPH + H+ + O2 <=> albaflavenone + NADP+ + H2O 1.14.13.106 epi-isozizaene 5-monooxygenase
–
methyl_ecgonine + NADP+ <=> methyl_ecgonone + NADPH + H+ 1.1.1.334 methylecgonone reductase
–
M
(11R)-dihydroartemisinic_aldehyde + NADP+ <=> artemisinic_aldehyde + NADPH + H+ 1.3.1.74 2-alkenal reductase [NAD(P)+]
1.3.1.92 artemisinic aldehyde Delta11(13)-reductase
–
–
BM
H+ + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl]acetyl-CoA + NADPH + O2 <=> [(2R)-3,3,4-trimethyl-6-oxo-3,6-dihydro-1H-pyran-2-yl]acetyl-CoA + NADP+ + H2O 1.14.13.160 (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA 1,5-monooxygenase
–
BM
(+)-Camphor + NADPH + H+ + O2 <=> N-(2-benzyl-3-[[(1R)-1-[[(benzyloxy)carbonyl]amino]-2-phenylethyl](hydroxy)phosphoryl]propanoyl)-L-tryptophan + NADP+ + H2O 1.14.13.161 (+)-camphor 6-exo-hydroxylase
–
nicotine_blue_leuco_form + NADP+ <=> nicotine_blue + NADPH + H+ 1.1.1.328 nicotine blue oxidoreductase
–
MK
2-deoxy-scyllo-inosamine + NADP+ <=> 3-amino-2,3-dideoxy-scyllo-inosose + NADPH + H+ 1.1.1.329 2-deoxy-scyllo-inosamine dehydrogenase
–
MK
4-oxo-4-(pyridin-3-yl)butanal + H2O + NADP+ <=> 4-oxo-4-(pyridin-3-yl)butanoate + NADPH + H+ 1.2.1.83 3-succinoylsemialdehyde-pyridine dehydrogenase
–
MK
palmitoyl-CoA + NADPH + H+ <=> hexadecanol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
behenoyl-CoA + NADP+ <=> trans-docos-2-enoyl-CoA + NADPH + H+ 1.3.1.93 very-long-chain enoyl-CoA reductase
–
MK
dolichol + NADP+ <=> di-trans,_poly-cis-polyprenol + NADPH + H+ 1.3.1.94 polyprenol reductase
1.3.1.B13
–
–
MK
Nomega-hydroxy-L-arginine + NADPH + O2 <=> L-citrulline + NO + NADP+ + H2O + H+ 1.14.13.39 nitric-oxide synthase (NADPH)
–
MK
a_3alpha-hydroxysteroid + NADP+ <=> 3-keto_steroid + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
3-oxo-5-alpha-steroid + NADP+ <=> a_3-oxo-DELTA4-steroid + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
reduced_adrenodoxin + NADP+ + H+ <=> oxidized_ferredoxin + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.6 adrenodoxin-NADP+ reductase
–
–
(2R)-3-sulfolactate + NADP+ <=> 3-sulfopyruvate + NADPH + H+ 1.1.1.338 (2R)-3-sulfolactate dehydrogenase (NADP+)
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
–
–
BMK
CDP-abequose + NADP+ <=> CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1.341 CDP-abequose synthase
4.2.1
–
–
MK
CDP-3,6-dideoxy-D-glucose + NADP+ <=> CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1.342 CDP-paratose synthase
–
MK
C30_botryococcene + diphosphate + NADP+ <=> presqualene_diphosphate + NADPH + H+ 1.3.1.97 botryococcene synthase
–
M
carboxyspermidine + H2O + NADP+ <=> L-aspartate_4-semialdehyde + putrescine + NADPH + H+ 1.4.1.B4
1.5.1.43 carboxynorspermidine synthase
–
–
BMK
FADH2 + NADP+ <=> FAD + NADPH + H+ 1.14.13.7 phenol 2-monooxygenase (NADPH)
1.18.1.2 ferredoxin---NADP+ reductase
1.5.1.30 flavin reductase (NADPH)
1.5.1.36 flavin reductase (NADH)
1.5.1.38 FMN reductase (NADPH)
1.5.1.41 riboflavin reductase [NAD(P)H]
1.5.1.45 FAD reductase [NAD(P)H]
–
–
–
–
–
–
–
BK
4-nitrocatechol + O2 + NADPH <=> 2-hydroxy-1,4-benzoquinone + nitrite + H2O + NADP+ + H+ 1.14.13.166 4-nitrocatechol 4-monooxygenase
1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
–
M
4-nitrophenol + O2 + NADPH + H+ <=> 1,4-benzoquinone + nitrite + H2O + NADP+ 1.14.13.167 4-nitrophenol 4-monooxygenase
1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
–
MK
3-Indole-2-oxopropanoate + NADPH + O2 + H+ <=> indole-3-acetic_acid + CO2 + NADP+ + H2O 1.14.13.168 indole-3-pyruvate monooxygenase
–
MK
1-deoxy-11-oxopentalenate + O2 + NADPH + H+ <=> pentalenolactone_D + H2O + NADP+ 1.14.13.170 pentalenolactone D synthase
–
MK
1-deoxy-11-oxopentalenate + O2 + NADPH + H+ <=> neopentalenolactone_D + H2O + NADP+ 1.14.13.171 neopentalenolactone D synthase
–
MK
2-keto-L-gulonate + NADP+ <=> 2,5-didehydro-D-gluconate + NADPH + H+ 1.1.1
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
BM
(+)-lariciresinol + NADP+ <=> (+)-pinoresinol + NADPH + H+ 1.23.1.1 (+)-pinoresinol reductase
1.23.1.2 (+)-lariciresinol reductase
–
–
MK
(-)-secoisolariciresinol + NADP+ <=> (+)-lariciresinol + NADPH + H+ 1.23.1.2 (+)-lariciresinol reductase
–
MK
(-)-lariciresinol + NADP+ <=> (-)-pinoresinol + NADPH + H+ 1.23.1.3 (-)-pinoresinol reductase
1.23.1.4 (-)-lariciresinol reductase
–
–
MK
(+)-secoisolariciresinol + NADP+ <=> (-)-lariciresinol + NADPH + H+ 1.23.1.3 (-)-pinoresinol reductase
1.23.1.4 (-)-lariciresinol reductase
–
–
MK
pyranose + NADP+ <=> an_aldono-1,5-lactone + NADPH + H+ 1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
–
B
agroclavine + NADP+ <=> 6,8-dimethyl-6,7,8,9-tetradehydroergoline + NADPH + H+ 1.5.1.46 agroclavine dehydrogenase
–
MK
5,6,7,8-tetrahydromethanopterin + NADP+ <=> 7,8-dihydromethanopterin + NADPH + H+ 1.5.1.47 dihydromethanopterin reductase [NAD(P)+]
–
BK
2,3-bis-O-phytanyl-sn-glycerol_1-phosphate + NADP+ <=> 2,3-bis-(O-geranylgeranyl)-sn-glycerol_1-phosphate + NADPH + H+ 1.3.1.101 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]
–
BMK
(4R)-4,2''-dihydroxyisoflavan + NADP+ <=> (3R)-2''-hydroxyisoflavanone + NADPH + H+ 1.1.1.348 (3R)-2'-hydroxyisoflavanone reductase
–
(1''S)-averantin + NADP+ <=> norsolorinic_acid + NADPH + H+ 1.1.1.349 norsolorinic acid ketoreductase
1.1.1.B25
–
–
MK
versiconol_acetate + NADP+ <=> versiconal_hemiacetal_acetate + NADPH 1.1.1.353 versiconal hemiacetal acetate reductase
–
MK
versiconol + NADP+ <=> versiconal + NADPH 1.1.1.353 versiconal hemiacetal acetate reductase
–
MK
dihydrochanoclavine-I_aldehyde + NADP+ <=> chanoclavine-I_aldehyde + NADPH + H+ 1.3.1.100 chanoclavine-I aldehyde reductase
–
MK
[2Fe-2S]-center + NADP+ + H+ <=> [2Fe-2S]-center + NADPH 1.18.1.7 ferredoxin---NAD(P)+ reductase (naphthalene dioxygenase ferredoxin-specific)
–
Caffeine + NADPH + O2 + H+ <=> Theobromine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
1.14.13.178 methylxanthine N1-demethylase
–
–
BMK
theophylline + NADPH + O2 + H+ <=> 3-Methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.178 methylxanthine N1-demethylase
–
MK
paraxanthine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
1.14.13.178 methylxanthine N1-demethylase
–
–
BMK
Theobromine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.179 methylxanthine N3-demethylase
–
MK
3-Methylxanthine + NADPH + O2 + H+ <=> xanthine + NADP+ + formaldehyde + H2O 1.14.13.179 methylxanthine N3-demethylase
–
MK
13-deoxydaunorubicin + NADPH + H+ + O2 <=> 13-dihydrodaunorubicin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
BMK
13-dihydrodaunorubicin + NADPH + H+ + O2 <=> daunorubicin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
BMK
aklavinone + NADPH + H+ + O2 <=> epsilon-rhodomycinone + NADP+ + H2O 1.14.13.180 aklavinone 12-hydroxylase
–
BMK
kanamycin_A + NADP+ <=> 2''-dehydrokanamycin_A + NADPH + H+ 1.1.1.355 2'-dehydrokanamycin reductase
–
MK
GDP-beta-L-colitose + NADP+ <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADPH + H+ 1.1.1.356 GDP-L-colitose synthase
–
MK
aklavinone + NADP+ <=> aklaviketone + NADPH + H+ 1.1.1.362 aklaviketone reductase
–
BMK
L-2-chloropropionate + NADP+ <=> 2-chloroacrylate + NADPH + H+ 1.3.1.103 2-haloacrylate reductase
1.3.1.31 2-enoate reductase
–
–
M
NADPH + H+ + O2 <=> NADP+ + H2O 1.6.3.2 NAD(P)H oxidase (H2O-forming)
–
B
Sulfide + NADP+ <=> sulfur + NADPH + H+ 1.12.7.2 ferredoxin hydrogenase
1.8.1.18 NAD(P)H sulfur oxidoreductase (CoA-dependent)
–
–
BM
4-hydroxy-2,5-dimethyl-3(2H)-furanone + NADP+ <=> 4-hydroxy-5-methyl-2-methylene-3(2H)-furanone + NADPH + H+ 1.3.1.105 2-methylene-furan-3-one reductase
–
M
dTDP-6-deoxy-alpha-D-allose + NADP+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose + NADPH + H+ 1.1.1.364 dTDP-4-dehydro-6-deoxy-alpha-D-gulose 4-ketoreductase
–
BMK
L-galactonate + NADP+ <=> aldehydo-D-galacturonate + NADPH + H+ 1.1.1.365 D-galacturonate reductase
–
M
5-methyl-1-naphthoate + NADPH + H+ + O2 <=> 3-hydroxy-5-methylnaphthoate + NADP+ + H2O 1.14.13.189 5-methyl-1-naphthoate 3-hydroxylase
–
D-glyceraldehyde + H2O + NADP+ <=> D-glycerate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
–
–
–
–
–
–
BK
hexadecanal + CoA + NADP+ <=> stearoyl-CoA + NADPH + H+ 1.2.1.42 hexadecanal dehydrogenase (acylating)
1.2.1.50 long-chain acyl-protein thioester reductase
1.2.1.84 alcohol-forming fatty acyl-CoA reductase
1.2.1.B25
–
–
–
–
K
(R)-2-methylpyrrolidine + NADP+ <=> 2-methyl-1-pyrroline + NADPH + H+ 1.5.1.48 2-methyl-1-pyrroline reductase
–
dTDP-beta-L-evernosamine + NADPH + H+ + O2 <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + NADP+ + H2O 1.14.13.187 L-evernosamine nitrososynthase
–
dTDP-beta-L-evernosamine + NADPH + O2 <=> dTDP-N-hydroxy-beta-L-evernosamine + NADP+ + H2O 1.14.13.187 L-evernosamine nitrososynthase
–
M
dTDP-N-hydroxy-beta-L-evernosamine + NADPH + H+ + O2 <=> dTDP-2,3,6-trideoxy-3-C-methyl-4-O-methyl-3-nitroso-beta-L-arabino-hexopyranose + NADP+ + H2O 1.14.13.187 L-evernosamine nitrososynthase
–
M
UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+ <=> UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose + NADPH + H+ 1.1.1.367 UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase
–
MK
scyllo-Inositol + NADP+ <=> scyllo-inosose + NADPH + H+ 1.1.1
1.1.1.371 scyllo-inositol 2-dehydrogenase (NADP+)
–
–
K
1,2-dihydro-beta-NAD(P) + H+ + O2 <=> NADP+ + H2O2 1.6.3.5 renalase
–
NADP+ + nicotinate <=> nicotinate-adenine_dinucleotide_phosphate + nicotinamide 2.4.99.20 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
3.2.2.5 NAD+ glycohydrolase
–
–
K
NADP+ <=> 2''-phospho-cyclic_ADP-ribose + nicotinamide 2.4.99.20 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase
–
NADP+ + 4-hydroxybutyrate <=> H+ + NADPH + succinate_semialdehyde 1.1.1
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.26 glyoxylate reductase
1.1.1.61 4-hydroxybutyrate dehydrogenase
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.B47
1.1.1.co
–
–
–
–
–
–
–
–
BMK
tetracenomycin_A2 + O2 + NADPH + H+ <=> tetracenomycin_C + H2O + NADP+ 1.14.13.200 tetracenomycin A2 monooxygenase-dioxygenase
–
MK
(S)-2-hydroxyacid + NADP+ <=> a_2-oxo_carboxylate + NADPH + H+ 1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
–
Dihydrosanguinarine + NADP+ <=> sanguinarine + NADPH 1.3.1.107 sanguinarine reductase
–
M
dihydrochelirubine + NADP+ <=> chelirubine + NADPH 1.3.1.107 sanguinarine reductase
–
M
L-allo-threonine + NADP+ <=> aminoacetone + CO2 + NADPH 1.1.1.381 3-hydroxy acid dehydrogenase
–
L-allo-threonine + NADP+ <=> L-2-amino-3-oxobutanoate + NADPH + H+ 1.1.1.276 serine 3-dehydrogenase (NADP+)
1.1.1.381 3-hydroxy acid dehydrogenase
–
–
K
3,6-anhydro-alpha-L-galactopyranose + NADP+ + H2O <=> 3,6-anhydro-L-galactonate + NADPH + H+ 1.2.1.92 3,6-anhydro-alpha-L-galactose dehydrogenase
–
acetyl-CoA + malonyl-CoA + H+ + NADPH <=> 5-methyl-1-naphthoate + CoA + CO2 + H2O + NADP+ 2.3.1.236 5-methylnaphthoic acid synthase
–
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> 10-deoxymethynolide + CoA + CO2 + H2O + NADP+ 2.3.1.239 10-deoxymethynolide synthase
–
MK
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> narbonolide + CoA + CO2 + H2O + NADP+ 2.3.1.240 narbonolide synthase
–
MK
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 2-hydroxy-5-methyl-1-naphthoate + CoA + CO2 + H2O + NADP+ 2.3.1.237 neocarzinostatin naphthoate synthase
–
K
dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+ 1.1.1.384 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
–
BMK
(4R)-ipsdienol + NADP+ <=> ipsdienone + NADPH + H+ 1.1.1.386 ipsdienol dehydrogenase
–
K
4-hydroxybenzaldehyde + NADP+ + H2O <=> 4-hydroxybenzoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.67 vanillin dehydrogenase
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
1.2.1.96 4-hydroxybenzaldehyde dehydrogenase (NADP+)
–
–
–
–
–
BMK
L-serine + NADP+ <=> L-2-amino-3-oxopropionate + NADPH + H+ 1.1.1.276 serine 3-dehydrogenase (NADP+)
–
(S)-2-amino-6-oxohexanoate + AMP + diphosphate + NADP+ <=> L-2-aminoadipate + ATP + NADPH + H+ 1.2.1.95 L-2-aminoadipate reductase
–
K
tetrahydro-L-threo-neopterin + NADP+ <=> H+ + 7,8-dihydro-L-monapterin + NADPH 1.5.1.34 6,7-dihydropteridine reductase
1.5.1.50 dihydromonapterin reductase
–
–
BMK
cholesterol + O2 + NADPH + H+ <=> 7-dehydrocholesterol + NADP+ + H2O 1.14.19.21 cholesterol 7-desaturase
–
BMK
NADH + H+ + NADP+ + reduced_ferredoxin_[iron-sulfur]_cluster <=> NAD+ + NADPH + oxidized_ferredoxin 1.6.1.4 NAD(P)+ transhydrogenase (ferredoxin)
–
rifampicin + O2 + NADPH <=> 2''-N-hydroxyrifampicin + NADP+ + H2O 1.14.13.211 rifampicin monooxygenase
–
aurachin_C + O2 + NADPH + H+ <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide + NADP+ + H2O 1.14.13.222 aurachin C monooxygenase/isomerase
–
K
(2S)-2-hydroxy-3-oxopropane-1-sulfonic_acid + H2O + NADP+ <=> (S)-3-sulfolactate + NADPH + H+ 1.2.1.97 3-sulfolactaldehyde dehydrogenase
–
M
1,6-dihydro-beta-NAD(P) + H+ + O2 <=> NADP+ + H2O2 1.6.3.5 renalase
–
demethylphylloquinone + NADPH + H+ <=> demethylphylloquinol + NADP+ 1.6.5.12 demethylphylloquinone reductase
–
MK
NADPH + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + CO2 <=> NADP+ + oxidized_ferredoxin + formate 1.17.1.M4
1.2.1.B29
–
–
lithocholic_acid + NADP+ <=> 3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
–
–
–
M
isolithocholic_acid + NADP+ <=> 3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
M
bacteriochlorophyll_a + NADP+ <=> geranylgeranyl-bacteriochlorophyllide_a + NADPH + H+ 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase
1.3.1.83 geranylgeranyl diphosphate reductase
–
–
K
4-methyl-5-nitrocatechol + O2 + NADPH <=> H+ + 2-hydroxy-5-methylquinone + NADP+ + nitrite + H2O 1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
MK
asperlicin_C + NADPH + H+ + O2 <=> asperlicin_E + NADP+ + H2O 1.14.13.216 asperlicin C monooxygenase
–
M
protodeoxyviolaceinate + O2 + NADPH + H+ <=> protoviolaceinate + NADP+ + H2O 1.14.13.217 protodeoxyviolaceinate monooxygenase
1.14.13.224 violacein synthase
–
–
MK
D-erythritol_1-phosphate + NADP+ <=> D-erythrulose_1-phosphate + NADPH + H+ 1.1.1.402 D-erythritol 1-phosphate dehydrogenase
–
M
resorcinol + NADPH + O2 + H+ <=> Hydroxyquinol + NADP+ + H2O 1.14.13.219 resorcinol 4-hydroxylase (NADPH)
–
MK
(2S,3R)-flavan-3-ol + NADP+ <=> anthocyanidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
aurachin_C + O2 + NADPH + H+ <=> 2-hydroxy-1a-methyl-7a-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one + NADP+ + H2O 1.14.13.222 aurachin C monooxygenase/isomerase
–
M
protoviolaceinate + O2 + NADPH + H+ <=> violaceinate + NADP+ + H2O 1.14.13.224 violacein synthase
–
MK
acetone + O2 + NADPH + H+ <=> methyl_acetate + NADP+ + H2O 1.14.13.226 acetone monooxygenase (methyl acetate-forming)
–
MK
jasmonic_acid + O2 + NADPH + H+ <=> trans-12-hydroxyjasmonate + NADP+ + H2O 1.14.13.228 jasmonic acid 12-hydroxylase
–
M
tert-butanol + O2 + NADPH + H+ <=> isobutane-1,2-diol + NADP+ + H2O 1.14.13.229 tert-butyl alcohol monooxygenase
–
M
tetracycline + O2 + NADPH + H+ <=> 11a-hydroxytetracycline + H2O + NADP+ 1.14.13.231 tetracycline 11a-monooxygenase
–
MK
6-methylpretetramide + NADPH + O2 + H+ <=> 4-hydroxy-6-methylpretetramide + NADP+ + H2O 1.14.13.232 6-methylpretetramide 4-monooxygenase
–
MK
4-hydroxy-6-methylpretetramide + NADPH + O2 + H+ <=> 4-de(dimethylamino)-4-oxoanhydrotetracycline + NADP+ + H2O 1.14.13.233 4-hydroxy-6-methylpretetramide 12a-monooxygenase
–
MK
5a,11a-dehydrotetracycline + O2 + NADPH + H+ <=> 5a,11a-dehydrooxytetracycline + H2O + NADP+ 1.14.13.234 5a,11a-dehydrotetracycline 5-monooxygenase
–
MK
2-methyl-2-butanol + O2 + NADPH + H+ <=> 3-methyl-2-buten-1-ol + NADP+ + H2O 1.14.19.48 tert-amyl alcohol desaturase
–
reduced_flavodoxin + NADP+ <=> flavin + NADPH + H+ 1.19.1.1 flavodoxin---NADP+ reductase
1.6.2.4 NADPH---hemoprotein reductase
–
–
L-arginine + NADP+ + H2O <=> 5-guanidino-2-oxopentanoate + NH3 + NADPH + H+ 1.4.1.25 L-arginine dehydrogenase
–
MK
magnesium_protoporphyrin_monomethyl_ester + O2 + NADPH + H+ <=> 131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
BMK
131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester + NADPH + H+ + O2 <=> 131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
BMK
131-oxo-magnesium-protoporphyrin_IX_13-monomethyl_ester + O2 + NADPH <=> divinyl_protochlorophyllide_a + NADP+ + H2O 1.14.13.81 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
–
BMK
4-hydroxybenzoyl-[4-hydroxyphenylalkanoate_synthase] + malonyl-CoA + NADPH + H+ <=> 17-(4-hydroxyphenyl)heptadecanoyl-[4-hydroxyphenylalkanoate_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.261 (4-hydroxyphenyl)alkanoate synthase
–
M
N-hydroxyaniline + NADP+ + H2O <=> 4-nitrophenyl + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
N-hydroxyaniline + NADP+ <=> nitrosobenzene + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
MK
nitrosobenzene + NADP+ + H2O <=> 4-nitrophenyl + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
MK
L-arginine + NADPH + H+ + O2 <=> L-citrulline + NO + NADP+ + H2O 1.14.13.39 nitric-oxide synthase (NADPH)
1.14.14.47 nitric-oxide synthase (flavodoxin)
–
–
MK
L-arginine + NADPH + H+ + O2 <=> Nomega-hydroxy-L-arginine + NADP+ + H2O 1.14.13.39 nitric-oxide synthase (NADPH)
–
MK
an_omega-(methylthio)alkyl-glucosinolate + O2 + NADPH + H+ <=> an_omega-(methylsulfinyl)alkyl-glucosinolate + H2O + NADP+ 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
Dimethylamine + O2 + NADPH + H+ <=> methylamine + formaldehyde + H2O + NADP+ 1.14.13.238 dimethylamine monooxygenase
–
M
L-carnitine + O2 + NADPH + H+ <=> (3R)-3-hydroxy-4-oxobutanoate + trimethylamine + NADP+ + H2O 1.14.13.239 carnitine monooxygenase
–
M
4-hydroxybenzoate + Br- + O2 + NADPH + H+ <=> 2,4-Dibromophenol + CO2 + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
4-hydroxybenzoate + Br- + O2 + NADPH + H+ <=> 3-Bromo-4-hydroxybenzoate + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
3-Bromo-4-hydroxybenzoate + Br- + O2 + NADPH + H+ <=> 2,4-Dibromophenol + CO2 + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
3,4-dihydroxybenzoate + Br- + O2 + NADPH + H+ <=> 3,5-dibromobenzene-1,2-diol + CO2 + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
3,4-dihydroxybenzoate + Br- + O2 + NADPH + H+ <=> 3-bromo-4,5-dihydroxybenzoic_acid + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
3-bromo-4,5-dihydroxybenzoic_acid + Br- + O2 + NADPH + H+ <=> 3,5-dibromobenzene-1,2-diol + CO2 + H2O + NADP+ 1.14.19.55 4-hydroxybenzoate brominase (decarboxylating)
–
M
dihydro-4-coumaroyl-CoA + NADP+ <=> 4-coumaroyl-CoA + NADPH + H+ 1.3.1.117 hydroxycinnamoyl-CoA reductase
–
MK
dihydroferuloyl-CoA + NADP+ <=> feruloyl-CoA + NADPH + H+ 1.3.1.117 hydroxycinnamoyl-CoA reductase
–
2-polyprenylphenol + O2 + NADPH + H+ <=> 2-polyprenyl-6-hydroxyphenol + H2O + NADP+ 1.14.13.240 2-polyprenylphenol 6-hydroxylase
–
K
3,4-dihydroxyphenyllactic_acid + NADP+ <=> 3,4-Dihydroxyphenylpyruvate + NADPH + H+ 1.1.1.237 hydroxyphenylpyruvate reductase
–
MK
AMP + diphosphate + NADP+ + L-tyrosinal <=> ATP + NADPH + L-tyrosine + H+ 1.2.1.101 L-tyrosine reductase
–
staphylopine + H2O + NADP+ <=> (2S)-2-amino-4-{[(1R)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino}butanoate + pyruvate + NADPH + H+ 1.5.1.52 staphylopine dehydrogenase
–
M
geranylgeranyl_diphosphate + NADPH + H+ <=> lycopaoctaene + NADP+ + diphosphate 2.5.1.148 lycopaoctaene synthase
–
prephytoene_diphosphate + NADPH + H+ <=> lycopaoctaene + NADP+ + diphosphate 2.5.1.148 lycopaoctaene synthase
–
M
malonyl-CoA + NADPH + NADH + H+ <=> (2E,5S,6E,8E,10E)-5-hydroxydodeca-2,6,8,10-tetraenal + CoA + CO2 + NADP+ + NAD+ + H2O 2.3.1.281 5-hydroxydodecatetraenal polyketide synthase
–
M
a_3beta-hydroxy-4alpha-methylsteroid-4beta-carboxylate + NADP+ <=> a_4alpha-methyl-3-oxosteroid + CO2 + NADPH 1.1.1.417 3beta-hydroxysteroid-4beta-carboxylate 3-dehydrogenase (decarboxylating)
–
a_palmitoyl-[(hydroxy)phthioceranic_acid_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> C40-phthioceranyl-[(hydroxy)phthioceranic_acid_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.287 phthioceranic/hydroxyphthioceranic acid synthase
–
a_palmitoyl-[(hydroxy)phthioceranic_acid_synthase] + (S)-methylmalonyl-CoA + NADPH + H+ <=> C37-phthioceranyl-[(hydroxy)phthioceranic_acid_synthase] + CoA + CO2 + NADP+ + H2O 2.3.1.287 phthioceranic/hydroxyphthioceranic acid synthase
–
cyclohexanecarboxyl-CoA + NADP+ <=> cyclohex-1-ene-1-carbonyl-CoA + NADPH + H+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.120 cyclohexane-1-carbonyl-CoA reductase (NADP+)
–
–
M
4-nitrobenzoyl-CoA + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> demethylluteothin + CO2 + CoA + NADP+ + H2O 2.3.1.289 aureothin polyketide synthase system
–
4-nitrobenzoyl-CoA + (S)-methylmalonyl-CoA + malonyl-CoA + NADPH + H+ <=> demethyldeoxyspectinabilin + CO2 + CoA + NADP+ + H2O 2.3.1.290 spectinabilin polyketide synthase system
–
19-(4-hydroxyphenyl)nonadecanoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C37-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + CO2 + CoA + NADP+ + H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
M
17-(4-hydroxyphenyl)heptadecanoyl-[(phenol)carboxyphthiodiolenone_synthase] + malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ <=> C35-(phenol)carboxyphthiodiolenone-[(phenol)carboxyphthiodiolenone_synthase] + CO2 + CoA + NADP+ + H2O 2.3.1.292 (phenol)carboxyphthiodiolenone synthase
–
M
(S)-8-oxocitronellyl_enol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.3.1.122 (S)-8-oxocitronellyl enol synthase
–
MK
(R)-8-oxocitronellyl_enol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+ 1.3.1.123 8-oxogeranial reductase
–
proline_betaine + NADPH + O2 + H+ <=> N-methyl-L-proline + formaldehyde + NADP+ + H2O 1.14.13.247 stachydrine N-demethylase
–
M
NADP+ + H2O <=> NAD+ + phosphate 3.1.3
3.1.3.1 alkaline phosphatase
3.1.3.108 nocturnin
–
–
–
MK
trans-2-enoyl-CoA + NADP+ <=> a_(2E,4Z)-2,4-dienoyl-CoA + NADPH + H+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
trans-3-enoyl-CoA + NADP+ <=> trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
M
trans-3-enoyl-CoA + NADP+ <=> a_(2E,4Z)-2,4-dienoyl-CoA + NADPH + H+ 1.3.1.124 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
–
M
D-xylose + NADP+ <=> D-xylono-1,4-lactone + NADPH + H+ 1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
–
MK
benzoyl-CoA + O2 + NADPH + H+ <=> 3-hydroxybenzoyl-CoA + H2O + NADP+ 1.14.13.58 benzoyl-CoA 3-monooxygenase
–
BM
3-hydroxyphenylacetate + NADPH + O2 + H+ <=> homogentisate + NADP+ + H2O 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase
–
K
NADPH + O2 + 4-hydroxybenzoate + H+ <=> NADP+ + CO2 + H2O + hydroquinone 1.14.13.64 4-hydroxybenzoate 1-hydroxylase
–
K
2-Hydroxycyclohexan-1-one + O2 + NADPH + H+ <=> 1-Oxa-2-oxo-7-hydroxycycloheptane + H2O + NADP+ 1.14.13.66 2-hydroxycyclohexanone 2-monooxygenase
–
K
NADP+ + codeine <=> H+ + NADPH + codeinone 1.1.1.218 morphine 6-dehydrogenase
1.1.1.247 codeinone reductase (NADPH)
–
–
MK
NADP+ + salutaridinol <=> H+ + NADPH + salutaridine 1.1.1.248 salutaridine reductase (NADPH)
–
MK
NADP+ + Scytalone <=> H+ + NADPH + 1,3,6,8-Tetrahydroxynaphthalene 1.1.1.252 tetrahydroxynaphthalene reductase
–
glycolaldehyde + NADP+ <=> Glyoxal + NADPH + H+ 1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
1-butanol + NADP+ <=> H+ + Butyraldehyde + NADPH 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
–
–
–
MK
trans-2-hexenol + NADP+ <=> trans-2-hexenal + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.265 3-methylbutanal reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
M
furfural + NADPH + H+ <=> Furfuryl_alcohol + NADP+ 1.1.1
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.265 3-methylbutanal reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
fatty_acid + O2 + NADPH + H+ <=> omega-hydroxy_fatty_acid + NADP+ + H2O 1.14.13
1.14.15.3 alkane 1-monooxygenase
–
–
M
(3R)-3-hydroxybutanoyl-[acyl-carrier_protein] + NADP+ <=> acetoacetyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
BMK
1-alkyl-sn-glycero-3-phosphate + NADP+ <=> O-alkylglycerone_phosphate + NADPH + H+ 1.1.1.101 acylglycerone-phosphate reductase
–
MK
(S)-2-amino-1-(R)-3-dihydroxyeicosane + NADP+ <=> (S)-2-amino-1-hydroxyeicosane-3-one + NADPH + H+ 1.1.1.102 3-dehydrosphinganine reductase
–
M
4-nitrobenzyl_alcohol + NADP+ <=> 4-nitrobenzaldehyde + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.65 pyridoxine 4-dehydrogenase
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
chenodeoxycholic_acid + NADP+ <=> 7alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.112 indanol dehydrogenase
1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
glycolaldehyde + H+ + NADPH <=> ethylene_glycol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
M
acetoin + NADP+ <=> diacetyl + NADPH + H+ 1.1.1
1.1.1.10 L-xylulose reductase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.162 erythrulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.292 1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.2.1.3 aldehyde dehydrogenase (NAD+)
–
–
–
–
–
–
–
–
–
–
–
–
–
–
2-phenylethanol + NADP+ <=> phenylacetaldehyde + NADPH + H+ 1.1.1
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.90 aryl-alcohol dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
M
Vanillyl_alcohol + NADP+ <=> Vanillin + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.2.1
–
–
–
isobutanol + NADP+ <=> Isobutyraldehyde + NADPH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
sinapyl_alcohol + NADP+ <=> sinapaldehyde + NADPH + H+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
BMK
ursocholate + NADP+ <=> 3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic_acid + NADPH + H+ 1.1.1.159 7alpha-hydroxysteroid dehydrogenase
1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
–
M
5alpha-androstane-3alpha,17beta-diol + NADP+ <=> 5alpha-dihydrotestosterone + NADPH + H+ 1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
K
L-Idonate + NADP+ <=> 2-keto-L-gulonate + NADPH + H+ 1.1.1
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
–
BM
5-Dehydro-D-gluconate + NADP+ <=> H+ + 2,5-didehydro-D-gluconate + NADPH 1.1.1
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
BM
Apiforol + NADP+ <=> naringenin + NADPH + H+ 1.1.1.234 flavanone 4-reductase
–
MK
luteoforol + NADP+ <=> eriodictyol + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
1.1.1.234 flavanone 4-reductase
–
–
MK
4alpha-methylcholest-7-en-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-cholest-7-en-3-one + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
avenasterol + NADP+ <=> avenastenone + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
MK
cycloeucalenol + NADP+ <=> cycloeucalenone + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
MK
(3R)-hydroxybutyryl-CoA + NADP+ <=> acetoacetyl-CoA + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase
1.1.1.36 acetoacetyl-CoA reductase
–
–
–
BMK
D-mannonate + NADP+ <=> D-fructuronate + NADPH + H+ 1.1.1
1.1.1.57 fructuronate reductase
–
–
cis-3-hexenal + NADPH + H+ <=> (3Z)-hex-3-en-ol + NADP+ 1.1.1
1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
M
trans-2-pentenol + NADP+ <=> trans-2-pentenal + NADPH + H+ 1.1.1
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
M
Hydroxyacetone + NADP+ <=> H+ + methylglyoxal + NADPH 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
MK
5-Oxopentanoate + NADP+ + H2O <=> Glutarate + NADPH + H+ 1.2.1
1.2.1.20 glutarate-semialdehyde dehydrogenase
–
–
M
H+ + sinapoyl-CoA + NADPH <=> sinapaldehyde + NADP+ + CoA 1.2.1.44 cinnamoyl-CoA reductase
–
K
4-coumaroyl-CoA + NADPH + H+ <=> 4-coumaraldehyde + CoA + NADP+ 1.2.1.44 cinnamoyl-CoA reductase
–
BMK
H+ + feruloyl-CoA + NADPH <=> coniferyl_aldehyde + NADP+ + CoA 1.2.1.44 cinnamoyl-CoA reductase
1.2.1.68 coniferyl-aldehyde dehydrogenase
–
–
BMK
methylglyoxal + NADP+ + H2O <=> H+ + pyruvate + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.23 2-oxoaldehyde dehydrogenase (NAD+)
1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
–
–
MK
4,4-dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> H+ + 4,4-dimethyl-5-alpha-cholesta-8,14-dien-3-beta-ol + NADPH 1.3.1.70 Delta14-sterol reductase
–
M
cholesterol + NADP+ <=> desmosterol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
MK
24,25-dihydrolanosterol + NADP+ <=> lanosterol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
MK
4,4-dimethyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
MK
cycloartanol + NADP+ <=> Cycloartenol + NADPH + H+ 1.3.1.72 Delta24-sterol reductase
–
M
methyl-1,4-benzoquinone + NADPH + H+ <=> methylhydroquinone + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.6.5
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
deoxycholate + NADP+ <=> 4-(1-Naphthylvinyl)pyridine + NADPH + H+ 1.1.1.176 12alpha-hydroxysteroid dehydrogenase
–
p-coumaryl_alcohol + NADP+ <=> 4-coumaraldehyde + NADPH + H+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
BMK
Leucocyanidin + NADP+ <=> taxifolin + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
MK
cis-3,4-leucopelargonidin + NADP+ <=> (+)-dihydrokaempferol + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
MK
3,4-cis-leucodelphinidin + NADP+ <=> dihydromyricetin + NADPH + H+ 1.1.1.219 dihydroflavonol 4-reductase
–
MK
2,5-dihydroxybenzaldehyde + NADP+ + H2O <=> 2,5-Dihydroxybenzoate + NADPH + H+ 1.2.1
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
3-Hydroxybenzaldehyde + NADP+ + H2O <=> 3-hydroxybenzoate + NADPH + H+ 1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.7 benzaldehyde dehydrogenase (NADP+)
–
–
MK
acetaldehyde + NADP+ + H2O <=> acetate + NADPH + H+ 1.2.1
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
–
–
–
–
–
–
–
–
–
BMK
propionaldehyde + H2O + NADP+ <=> propionate + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.22 lactaldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
1.5.1.6 formyltetrahydrofolate dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
M
Dihydrothymine + NADP+ <=> thymine + NADPH + H+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
–
BM
prostaglandin_F2alpha + NADP+ <=> prostaglandin_H2 + NADPH + H+ 1.1.1
1.1.1.188 prostaglandin-F synthase
1.1.1.189 prostaglandin-E2 9-reductase
1.6.99.1 NADPH dehydrogenase
–
–
–
–
K
cholic_acid + NADP+ <=> 7alpha,12alpha-dihydroxy-5beta-cholan-3-one-24-oic_acid + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.52 3alpha-hydroxycholanate dehydrogenase (NAD+)
–
–
–
–
deoxycholate + NADP+ <=> 12alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1
1.1.1.392 3alpha-hydroxycholanate dehydrogenase (NADP+)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
M
5beta-androstane-3,17-dione + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+ 1.3.1
1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
–
K
7alpha,12alpha-dihydroxy-4-cholesten-3-one + NADPH + H+ <=> 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
BMK
acrolein + NADPH + H+ <=> propionaldehyde + NADP+ 1.3.1
1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
1.6.99.1 NADPH dehydrogenase
–
–
–
–
–
–
M
5alpha-dihydroprogesterone + NADP+ <=> progesterone + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
–
–
MK
5alpha-dihydrotestosterone + NADP+ <=> testosterone + H+ + NADPH 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor)
–
–
MK
trans-2-decenoyl-CoA + NADP+ <=> 2-trans,4-cis-decadienoyl-CoA + NADPH + H+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
17alpha,21-dihydroxy-5alpha-pregnan-3,11,20-trione + NADP+ <=> cortisone + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
(3R)2',7-dihydroxy-dihydro-4',5'-methylenedioxyisoflavone + NADP+ <=> 2''-hydroxypseudobaptigenin + NADPH + H+ 1.3.1.45 2'-hydroxyisoflavone reductase
–
MK
3-buten-2-one + NADPH + H+ <=> 2-butanone + NADP+ 1.3.1
1.3.1.27 2-hexadecenal reductase
1.3.1.31 2-enoate reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
–
–
–
–
–
–
M
1-penten-3-one + NADPH + H+ <=> 3-Pentanone + NADP+ 1.3.1
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
–
M
palmitoyl-CoA + NADP+ <=> trans-2-hexadecenoyl-CoA + NADPH + H+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
BMK
arachidoyl-CoA + NADP+ <=> (2E)-eicosenoyl-CoA + NADPH + H+ 1.3.1.8 acyl-CoA dehydrogenase (NADP+)
1.3.1.93 very-long-chain enoyl-CoA reductase
–
–
M
2,5-Diaminohexanoate + H2O + NADP+ <=> 2-Amino-5-oxohexanoate + NH3 + NADPH + H+ 1.4.1.12 2,4-diaminopentanoate dehydrogenase
–
L-pipecolic_acid + NADP+ <=> DELTA1-piperidine_6-carboxylate + NADPH + H+ 1.5.1
1.5.1.2 pyrroline-5-carboxylate reductase
–
–
M
ascorbate + NADP+ + H+ <=> ascorbate + NADPH 1.6.5
1.6.5.4 monodehydroascorbate reductase (NADH)
–
–
M
dihydrolipoamide + NADP+ <=> Lipoamide + NADPH + H+ 1.8.1
1.8.1.4 dihydrolipoyl dehydrogenase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
5alpha-Cholestan-3-one + NADP+ <=> cholest-4-en-3-one + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
stearoyl-CoA + NADPH + O2 + H+ <=> oleoyl-CoA + NADP+ + H2O 1.14.19
1.14.19.1 stearoyl-CoA 9-desaturase
1.14.19.M26
–
–
–
K
N-ethylsuccinimide + NADP+ <=> N-ethylmaleimide + NADPH + H+ 1.14.13.40 anthraniloyl-CoA monooxygenase
1.3.1
1.3.1.31 2-enoate reductase
–
–
–
H+ + Cyclohexane + O2 + NADPH <=> Cyclohexanol + H2O + NADP+ 1.14.13.25 methane monooxygenase (soluble)
1.14.15.3 alkane 1-monooxygenase
–
–
ethyl_(2R)-methyl-(3S)-hydroxybutanoate + NADP+ <=> ethyl_2-methylacetoacetate + NADPH + H+ 1.1.1
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.280 (S)-3-hydroxyacid-ester dehydrogenase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
–
–
tetrahydrobiopterin + NADP+ <=> (6R)-L-erythro-6,7-dihydrobiopterin + NADPH + H+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase
–
–
–
K
(-)-limonene + O2 + NADPH + H+ <=> (-)-cis-carveol + H2O + NADP+ 1.14.13
1.14.14.53 (R)-limonene 6-monooxygenase
–
–
NADPH + vitamin_K + H+ <=> NADP+ + vitamin_KH2 1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
M
4alpha-methyl-5alpha-ergosta-8,24-dien-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+ 1.3.1.70 Delta14-sterol reductase
–
MK
desmosterol + NADP+ <=> Cholesta-5,7,24-trienol + NADPH + H+ 1.3.1.21 7-dehydrocholesterol reductase
–
M
H+ + 3-hydroxypropionate + ATP + CoA + NADPH <=> propionyl-CoA + AMP + diphosphate + H2O + NADP+ 6.2.1.17 propionate---CoA ligase
–
cortisol + NADP+ <=> cortisone + NADPH + H+ 1.1.1
1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.B40
–
–
–
K
sitosterol + NADP+ <=> isofucosterol + NADPH + H+ 1.3.1
1.3.1.70 Delta14-sterol reductase
1.3.1.72 Delta24-sterol reductase
1.3.1.M20
–
–
–
–
K
11-cis-retinol + NADP+ <=> 11-cis-retinal + NADPH + H+ 1.1.1
1.1.1.300 NADP-retinol dehydrogenase
1.1.1.315 11-cis-retinol dehydrogenase
–
–
–
K
3-aminopropionaldehyde + NADP+ + H2O <=> beta-Alanine + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
BM
4-Aminobutyraldehyde + NADP+ + H2O <=> 4-aminobutanoate + NADPH + H+ 1.2.1
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
–
–
–
K
4-hydroxybutanal + NADPH + H+ <=> 1,4-Butanediol + NADP+ 1.1.1
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
epicatechin + NADP+ <=> cyanidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
–
MK
epigallocatechin + NADP+ <=> delphinidin + NADPH + H+ 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
MK
(-)-epiafzelechin + NADP+ <=> H+ + pelargonidin + NADPH 1.3.1.112 anthocyanidin reductase [(2S)-flavan-3-ol-forming]
1.3.1.77 anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
–
–
MK
UDP-L-rhamnose + NADP+ <=> UDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ 1.1.1
1.1.1.133 dTDP-4-dehydrorhamnose reductase
–
–
Zymosterol + NADP+ <=> H+ + zymosterone + NADPH 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
BMK
3-chlorophenol + O2 + NADPH + H+ <=> 4-Chlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
1.14.13.7 phenol 2-monooxygenase (NADPH)
–
–
M
2-chlorophenol + O2 + NADPH + H+ <=> 3-chlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
1.14.13.7 phenol 2-monooxygenase (NADPH)
–
–
M
H+ + (+)-isomenthone + NADPH <=> (+)-isomenthol + NADP+ 1.1.1.208 (+)-neomenthol dehydrogenase
–
M
H+ + (+)-isomenthone + NADPH <=> d-neoisomenthol + NADP+ 1.1.1.207 (-)-menthol dehydrogenase
–
M
L-threo-(6R,1'S,2'S)-5,6,7,8-tetrahydrobiopterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
–
–
Nicotine + NADPH + O2 <=> nicotine-1''-N-oxide + NADP+ + H2O 1.14.13.101 senecionine N-oxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
M
4-Chlorophenol + O2 + NADPH + H+ <=> 4-Chlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
1.14.13.7 phenol 2-monooxygenase (NADPH)
–
–
MK
4-nitrophenol + NADPH + O2 + H+ <=> 4-nitrocatechol + NADP+ + H2O 1.14.13.29 4-nitrophenol 2-monooxygenase
–
(R)-2-hydroxyisocaproate + NADP+ <=> 4-methyl-2-oxopentanoate + NADPH + H+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
–
D-2-hydroxybutyrate + NADP+ <=> 2-oxobutyrate + NADPH + H+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.28 D-lactate dehydrogenase
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
–
palmitoyl-CoA + NADPH + O2 + H+ <=> palmitoleoyl-CoA + NADP+ + H2O 1.14.19.1 stearoyl-CoA 9-desaturase
1.14.19.M26
–
–
5beta-pregnane-3,20-dione + NADP+ <=> progesterone + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
1.3.1.M16
1.3.99.6 3-oxo-5beta-steroid 4-dehydrogenase
–
–
–
–
–
MK
trans-phytenoyl-CoA + NADPH + H+ <=> phytanoyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
–
M
(4R)-dihydrocarvone + NADPH + H+ + O2 <=> (4R)-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(1R,4S)-1-hydroxy-2-oxolimonene + O2 + NADPH <=> (3S)-3-isopropenyl-6-oxoheptanoate + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(1S,4R)-1-hydroxy-2-oxolimonene + O2 + NADPH <=> (3R)-3-isopropenyl-6-oxoheptanoate + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(1S,4R)-menthone + NADPH + H+ + O2 <=> (4S,7R)-7-isopropyl-4-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
13,14-dihydro-15-keto-prostaglandin_E2 + NADP+ <=> 15-ketoprostaglandin_E2 + NADPH + H+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
7alpha-hydroxy-4-cholesten-3-one + NADPH + H+ <=> 7alpha-hydroxy-5beta-cholestan-3-one + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
BMK
dodecanoyl-[acyl-carrier_protein] + NADP+ <=> dodecenoyl-[Staphylococcus_aureus_acyl_carrier_protein] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
L-lactaldehyde + NADP+ + H2O <=> L-lactate + NADPH + H+ 1.2.1
1.2.1.22 lactaldehyde dehydrogenase
–
–
BM
3-sulfopropanal + NADP+ + H2O <=> 3-Sulfopropanoate + NADPH + H+ 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
–
M
1,3-Propanediol + NADP+ <=> 3-hydroxypropionaldehyde + NADPH + H+ 1.1.1
1.1.1.202 1,3-propanediol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
M
hexanal + CoA + NADP+ <=> hexanoyl-CoA + NADPH + H+ 1.2.1
1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
–
–
M
7-hydroxymethylchlorophyll_a + NADP+ <=> chlorophyll_b + NADPH 1.1.1.294 chlorophyll(ide) b reductase
–
BMK
Ethionamide + NADPH + O2 + H+ <=> ethionamide_S-oxide + NADP+ + H2O 1.14.13
1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
–
–
M
3-hydroxypropionaldehyde + NADP+ + H2O <=> 3-hydroxypropionate + NADPH + H+ 1.2.1.99 4-(gamma-glutamylamino)butanal dehydrogenase
–
(R)-2-methylmalonyl-CoA + NADP+ <=> acryloyl-CoA + CO2 + NADPH 1.3.1.85 crotonyl-CoA carboxylase/reductase
–
M
triethylamine + O2 + NADPH + H+ <=> Triethylamine_N-oxide + H2O + NADP+ 1.14.13
1.14.13.8 flavin-containing monooxygenase
–
–
M
erythromycin_B + O2 + NADPH + H+ <=> erythromycin + H2O + NADP+ 1.14.13.154 erythromycin 12-hydroxylase
–
MK
Caffeine + NADPH + O2 + H+ <=> paraxanthine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
1.14.13.179 methylxanthine N3-demethylase
1.14.14.1 unspecific monooxygenase
–
–
–
MK
trans-anol + acetate + NADP+ <=> 4-coumaryl_acetate + NADPH 1.1.1
1.1.1.319 isoeugenol synthase
–
–
MK
eugenol + acetate + NADP+ <=> coniferyl_acetate + NADPH 1.1.1.318 eugenol synthase
–
BMK
(3R,4R)-7,2''-dihydroxy-4''-methoxyisoflavanol + NADP+ <=> vestitone + NADPH + H+ 1.1.1.348 (3R)-2'-hydroxyisoflavanone reductase
–
MK
13-deoxycarminomycin + NADPH + H+ + O2 <=> 13-dihydrocarminomycin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
BMK
13-dihydrocarminomycin + NADPH + H+ + O2 <=> carminomycin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
BMK
daunorubicin + NADPH + H+ + O2 <=> doxorubicin + NADP+ + H2O 1.14.13.181 13-deoxydaunorubicin hydroxylase
–
MK
5,5''-dimethoxylariciresinol + NADP+ <=> (+/-)-syringaresinol + NADPH + H+ 1.23.1
1.23.1.1 (+)-pinoresinol reductase
–
–
(3R)-3-hydroxy-arachidoyl-CoA + NADP+ <=> 3-oxo-arachidoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
(3R)-3-hydroxy-lignoceroyl-CoA + NADP+ <=> 3-oxo-lignoceroyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
M
2-hydroxypropiophenone + NADP+ <=> 1-phenyl-1,2-propanedione + NADPH + H+ 1.1.1.320 benzil reductase [(S)-benzoin forming]
–
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> 3-dehydro-4-methylzymosterol + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
BMK
4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-cholesta-8-en-3-one + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
M
4alpha-carboxy-5alpha-cholesta-8,24-dien-3beta-ol + NADP+ <=> zymosterone + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
BMK
4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol + NADP+ <=> 5alpha-cholesta-8-en-3-one + CO2 + NADPH 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
M
4alpha-methylzymosterol + NADP+ <=> H+ + 3-dehydro-4-methylzymosterol + NADPH 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
MK
5beta-cholestane-3alpha,7alpha,12alpha-triol + NADP+ <=> 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
BMK
5beta-cholestane-3alpha,7alpha-diol + NADP+ <=> 7alpha-hydroxy-5beta-cholestan-3-one + NADPH + H+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
BMK
epsilon-rhodomycinone + NADP+ <=> maggiemycin + NADPH + H+ 1.1.1.362 aklaviketone reductase
–
cis-3,4-dehydroadipyl-CoA_semialdehyde + NADP+ + H2O <=> cis-3,4-dehydroadipyl-CoA + NADPH + H+ 1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
–
MK
4-chloro-2-methylphenol + O2 + NADPH + H+ <=> 3-methyl-5-chlorocatechol + H2O + NADP+ 1.14.13.20 2,4-dichlorophenol 6-monooxygenase
–
M
4-hexen-3-one + NADPH + H+ <=> hexan-3-one + NADP+ 1.3.1
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
M
ursodeoxycholate + NADP+ <=> 7-ketolithocholic_acid + NADPH + H+ 1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
–
M
chlorophyllide_a + NADP+ <=> divinyl_chlorophyllide_a + NADPH + H+ 1.3.1.75 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH)
–
MK
hexadecanal + [acyl-carrier_protein] + NADP+ <=> palmitoyl-[acyl-carrier_protein] + NADPH + H+ 1.2.1.50 long-chain acyl-protein thioester reductase
1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
–
M
3,4-Dihydroxybenzaldehyde + NADP+ + H2O <=> 3,4-dihydroxybenzoate + NADPH + H+ 1.2.1.67 vanillin dehydrogenase
–
M
UDP-2-acetamido-2,6-dideoxy-beta-L-talose + NADP+ <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + NADPH + H+ 1.1.1.367 UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase
–
tetracenomycin_B2 + O2 + NADPH + H+ <=> 8-demethyltetracenomycin_C + H2O + NADP+ 1.14.13.200 tetracenomycin A2 monooxygenase-dioxygenase
–
BMK
chelerythrine + NADPH <=> Dihydrochelerythrine + NADP+ 1.3.1.107 sanguinarine reductase
–
M
3-Methyl-4-hydroxybenzaldehyde + NADP+ + H2O <=> 4-hydroxy-3-methylbenzoate + NADPH + H+ 1.2.1.96 4-hydroxybenzaldehyde dehydrogenase (NADP+)
–
MK
reduced_ferredoxin_[iron-sulfur]_cluster + NADPH + H+ <=> oxidized_ferredoxin + NADP+ + H2 1.17.1.M4
1.2.1.B29
–
–
3beta,12alpha-dihydroxy-5beta-cholanoate + NADP+ <=> 12alpha-Hydroxy-3-oxo-5beta-cholan-24-oic_acid + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
M
3 beta-hydroxy-7,12-diketocholanate + NADP+ <=> dehydrocholate + NADPH + H+ 1.1.1.393 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
–
a_3beta-hydroxysteroid-4alpha-carboxylate + NADP+ <=> 3-keto_steroid + NADPH + CO2 1.1.1.170 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
–
bilirubin_IXbeta + NADP+ <=> biliverdin_IXbeta + NADPH + H+ 1.3.1.24 biliverdin reductase
–
isocitrate + NADP+ <=> oxalosuccinate + NADPH + H+ 1.1.1.42 isocitrate dehydrogenase (NADP+)
–
K
4-chloro-N-hydroxyaniline + NADP+ + H2O <=> 4-chloronitrobenzene + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
4-nitrotoluene + NADPH + H+ <=> 4-hydroxyaminotoluene + H2O + NADP+ 1.7.1
1.7.1.16 nitrobenzene nitroreductase
–
–
M
octadecanal + NADP+ + [acyl-carrier_protein] <=> stearoyl-[acyl-carrier_protein] + NADPH + H+ 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
M
4-hydroxybutanoyl-CoA + NADPH + H+ <=> 4-hydroxybutanal + NADP+ + CoA 1.2.1.57 butanal dehydrogenase
–
(2R,3R,6S)-Virginiae_butanolide-A + NADP+ <=> 6-dehydro-Virginiae_butanolide-A + NADPH + H+ 1.1.1.413 A-factor type gamma-butyrolactone 1'-reductase (1S-forming)
–
glucoerucin + O2 + NADPH + H+ <=> 4-methylsulfinylbutylglucosinolate + H2O + NADP+ 1.14.13.237 aliphatic glucosinolate S-oxygenase
–
M
myristoyl-CoA + NADPH + H+ <=> Tetradecanol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
M
stearoyl-CoA + NADPH + H+ <=> octadecanol + CoA + NADP+ 1.2.1.84 alcohol-forming fatty acyl-CoA reductase
–
campesterol + NADP+ <=> 24-methylene_cholesterol + NADPH + H+ 1.3.1
1.3.1.72 Delta24-sterol reductase
1.3.1.M20
–
–
–
K
4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate_6-semialdehyde + NADP+ <=> stizolobate + NADPH + H+ 1.13.11.29 stizolobate synthase
–
K
2'-Hydroxydihydrogenistein + NADP+ <=> 2''-hydroxygenistein + NADPH + H+ 1.3.1.51 2'-hydroxydaidzein reductase
–
M
L-Xylose + NADP+ <=> L-xylono-1,4-lactone + NADPH + H+ 1.1.1.113 L-xylose 1-dehydrogenase
1.1.1.116 D-arabinose 1-dehydrogenase (NAD+)
1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.B35
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
D-ribose + NADP+ + H2O <=> D-ribonate + NADPH + H+ 1.1.1.115 ribose 1-dehydrogenase (NADP+)
–
D-galactose + NADP+ <=> D-galactono-1,5-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
K
L-sorbose + NADP+ <=> 5-dehydro-D-fructose + NADPH + H+ 1.1.1.123 sorbose 5-dehydrogenase (NADP+)
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.346 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
–
–
–
D-fructose + NADP+ <=> 5-dehydro-D-fructose + NADPH + H+ 1.1.1.124 fructose 5-dehydrogenase (NADP+)
1.1.1.69 gluconate 5-dehydrogenase
–
–
D-mannitol + NADP+ <=> D-fructose + NADPH + H+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.14 L-iditol 2-dehydrogenase
1.1.1.21 aldose reductase
1.1.1.287 D-arabinitol dehydrogenase (NADP+)
1.1.1.289 sorbose reductase
1.1.1.67 mannitol 2-dehydrogenase
–
–
–
–
–
–
K
L-gulonate + NADP+ <=> D-glucuronate + NADPH + H+ 1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.20 glucuronolactone reductase
1.1.1.21 aldose reductase
–
–
–
–
BK
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.21 aldose reductase
1.1.1.220 6-pyruvoyltetrahydropterin 2'-reductase
–
–
–
–
K
(R)-mevalonate + NADP+ <=> DL-mevaldate + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.32 mevaldate reductase
1.1.1.33 mevaldate reductase (NADPH)
–
–
–
(R)-3-hydroxyvaleryl-CoA + NADP+ <=> 3-oxoacyl-CoA + NADPH + H+ 1.1.1.36 acetoacetyl-CoA reductase
–
R-CHOH-R' + NADP+ <=> acetone + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
–
D-arabinose + NADP+ <=> D-arabinono-1,4-lactone + NADPH + H+ 1.1.1.113 L-xylose 1-dehydrogenase
1.1.1.116 D-arabinose 1-dehydrogenase (NAD+)
1.1.1.117 D-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.122 D-threo-aldose 1-dehydrogenase
1.1.1.B35
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
BK
1,2-propanediol + NADP+ <=> L-lactaldehyde + NADPH + H+ 1.1.1.21 aldose reductase
1.1.1.55 lactaldehyde reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
acyl-[acyl-carrier_protein] + NADP+ <=> trans-2,3-dehydroacyl-[acyl-carrier_protein] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
–
–
–
–
K
5-methyltetrahydrofolate + NADP+ <=> 5,10-methylenetetrahydrofolate + NADPH + H+ 1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
–
BK
10-formyltetrahydrofolate + H2O + NADP+ <=> tetrahydrofolate + CO2 + NADPH + H+ 1.5.1.6 formyltetrahydrofolate dehydrogenase
–
K
chlorophyllide_a + NADP+ <=> protochlorophyllide + NADPH + H+ 1.3.1.33 protochlorophyllide reductase
–
BK
thioredoxin + NADP+ <=> thioredoxin_disulfide + NADPH + H+ 1.8.1.9 thioredoxin-disulfide reductase
1.8.1.B1
–
–
M
(-)-menthol + O2 + NADPH + H+ <=> p-Menthane-3,8-diol + H2O + NADP+ 1.14.13.46 (-)-menthol monooxygenase
–
protein-dithiol + NADP+ <=> protein_disulfide + NADPH + H+ 1.8.1.8 protein-disulfide reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
3-Hydroxy-2-methylpyridine-5-carboxylate + NADPH + H+ + O2 <=> 2-(Acetamidomethylene)succinate + NADP+ 1.14.13.242 3-hydroxy-2-methylpyridine-5-carboxylate monooxygenase
–
K
dUMP + 5,10-methylenetetrahydrofolate + NADPH + H+ <=> dTMP + tetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase
2.1.1.148 thymidylate synthase (FAD)
–
–
MK
(S)-4-Amino-5-oxopentanoate + NADP+ + tRNAMet <=> Glu-tRNAGln + NADPH + H+ 1.2.1.70 glutamyl-tRNA reductase
–
BK
sorbitol + NADP+ <=> L-sorbose + NADPH + H+ 1.1.1.14 L-iditol 2-dehydrogenase
1.1.1.289 sorbose reductase
1.1.1.B60
1.1.99.21 D-sorbitol dehydrogenase (acceptor)
–
–
–
–
K
7-hydroxychlorophyllide_a + NADP+ <=> chlorophyllide_b + NADPH + H+ 1.1.1.294 chlorophyll(ide) b reductase
–
K
(+)-limonene + NADPH + H+ + O2 <=> (R)-1,2-epoxy-limonene + NADP+ + H2O 1.14.13.107 limonene 1,2-monooxygenase
–
MK
hexadecanal + [acyl-carrier_protein] + NADP+ <=> stearoyl-[acyl-carrier_protein] + NADPH + H+ 1.2.1.80 long-chain acyl-[acyl-carrier-protein] reductase
–
10beta-hydroxytaxa-4(20),11-dien-5alpha-yl_acetate + O2 + NADPH + H+ <=> 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl_acetate + NADP+ + H2O 1.14.13.146 taxoid 14beta-hydroxylase
–
BK
taxusin + O2 + NADPH + H+ <=> 7beta-hydroxytaxusin + NADP+ + H2O 1.14.13.147 taxoid 7beta-hydroxylase
–
(-)-endo-fenchol + NADP+ <=> (+)-fenchone + NADPH + H+ 1.1.1.322 (-)-endo-fenchol dehydrogenase
–
L-threo-tetrahydrobiopterin + 2 NADP+ <=> 6-pyruvoyltetrahydropterin + 2 NADPH + 2 H+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325 sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
–
–
K
a_very-long-chain_(3R)-3-hydroxyacyl-CoA + NADP+ <=> a_very-long-chain_3-oxoacyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
K
7-hydroxychlorophyllide_a + O2 + NADPH + H+ <=> chlorophyllide_b + 2 H2O + NADP+ 1.14.13.122 chlorophyllide-a oxygenase
–
BK
versicolorone + NADP+ <=> 1'-hydroxyversicolorone + NADPH 1.1.1.353 versiconal hemiacetal acetate reductase
–
MK
L-arabinose + NADP+ <=> L-arabinono-1,4-lactone + NADPH + H+ 1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.46 L-arabinose 1-dehydrogenase
–
–
–
–
BK
L-rhamnose + NADP+ <=> L-Rhamno-1,4-lactone + NADPH + H+ 1.1.1.173 L-rhamnose 1-dehydrogenase
1.1.1.377 L-rhamnose 1-dehydrogenase (NADP+)
1.1.1.378 L-rhamnose 1-dehydrogenase [NAD(P)+]
–
–
–
BK
5-dehydroepisterol + NADPH + H+ + O2 <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP+ + 2 H2O 1.14.19.41 sterol 22-desaturase
–
K
[F-actin]-L-methionine + NADPH + O2 + H+ <=> [F-actin]-L-methionine-(R)-S-oxide + NADP+ + H2O 1.14.13.225 F-actin monooxygenase
–
a_(2R,3S)-2-alkyl-3-hydroxyalkanoate + NADP+ <=> an_(R)-2-alkyl-3-oxoalkanoate + NADPH + H+ 1.1.1.412 2-alkyl-3-oxoalkanoate reductase
–
M
a_(3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP+ <=> a_(3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH + H+ 1.1.1.413 A-factor type gamma-butyrolactone 1'-reductase (1S-forming)
–
biphenyl + NADPH + O2 <=> cis-2,3-dihydro-2,3-dihydroxybiphenyl + NADP+ 1.14.12.18 biphenyl 2,3-dioxygenase
1.14.12.22 carbazole 1,9a-dioxygenase
–
–
K
acyldihydroxyacetone_phosphate + NADPH <=> lysophosphatidic_acid + NADP+ 1.1.1.101 acylglycerone-phosphate reductase
–
K
5beta-Pregnan-3alpha-ol-20-one + NADP+ <=> 5beta-pregnane-3,20-dione + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
K
5beta-androstane-3,17-dione + NADPH <=> 5beta-androstane-3alpha-ol-17-one + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
–
–
K
L-galactopyranose + NADP+ <=> L-galactono-1,5-lactone + NADPH + H+ 1.1.1
1.1.1.116 D-arabinose 1-dehydrogenase (NAD+)
1.1.1.B35
–
–
–
MK
dTDP-4-dehydro-6-deoxy-D-glucose + NADPH + H+ <=> dTDP-L-rhamnose + NADP+ 1.1.1
1.1.1.133 dTDP-4-dehydrorhamnose reductase
–
–
K
androst-4-ene-3,11,17-trione + NADPH <=> 11beta-hydroxyandrost-4-ene-3,17-dione + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
K
progesterone + NADPH <=> 20alpha-hydroxyprogesterone + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.189 prostaglandin-E2 9-reductase
1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
–
–
–
–
–
K
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADPH + H+ <=> tetrahydrobiopterin + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
–
K
nerol + NADP+ <=> neral + NADPH 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.324 8-hydroxygeraniol dehydrogenase
–
–
–
K
1,2-propanediol + NADP+ <=> lactaldehyde + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.55 lactaldehyde reductase (NADPH)
–
–
–
–
9-cis-retinol + NADP+ <=> 9-cis-retinal + NADPH 1.1.1
1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.300 NADP-retinol dehydrogenase
1.1.1.315 11-cis-retinol dehydrogenase
–
–
–
–
–
–
–
K
Naphthalene_dihydrodiol + NADP+ <=> 1,2-dihydroxynaphthalene + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
K
5alpha-pregnane-3alpha,20alpha-diol + NADP+ <=> 5alpha-pregnan-20alpha-ol-3-one + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
–
K
5alpha-Pregnan-3alpha,21-diol-20-one + NADP+ <=> 5alpha-pregnane-21-ol-3,20-dione + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
–
–
K
L-arabitol + NADP+ <=> L-arabinopyranose + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.307 D-xylose reductase
–
–
–
MK
D-glucose + NADPH <=> sorbitol + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
K
galactitol + NADP+ <=> D-galactose + NADPH + H+ 1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
MK
phenylpyruvate + NADPH <=> D-phenyllactate + NADP+ 1.1.1.110 aromatic 2-oxoacid reductase
1.1.1.237 hydroxyphenylpyruvate reductase
1.1.1.28 D-lactate dehydrogenase
1.1.1.79 glyoxylate reductase (NADP+)
–
–
–
–
K
androstenediol + NADP+ <=> dehydroepiandrosterone + NADPH 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
K
caffeoyl-CoA + NADPH <=> caffeoyl_aldehyde + CoA + NADP+ 1.2.1.44 cinnamoyl-CoA reductase
–
K
4-carboxy-2-hydroxy-cis,cis-muconate_6-semialdehyde + NADP+ <=> 4-carboxy-2-hydroxy-cis,cis-muconate + NADPH 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
–
5-carboxymethyl-2-hydroxymuconate_semialdehyde + H2O + NADP+ <=> 5-Carboxymethyl-2-hydroxymuconate + NADPH 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
–
–
K
Zymosterol + NADPH <=> 5alpha-cholesta-8-en-3beta-ol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
K
Cholesta-5,7,24-trienol + NADPH + H+ <=> 7-dehydrocholesterol + NADP+ 1.3.1.72 Delta24-sterol reductase
–
K
phenylacetaldehyde + NADP+ + H2O <=> phenylacetate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.39 phenylacetaldehyde dehydrogenase
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
K
5-fluorouracil + NADPH <=> 5-fluoro-5,6-dihydrouracil + NADP+ 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2 dihydropyrimidine dehydrogenase (NADP+)
–
–
K
3alpha,17alpha,21-trihydroxy-5beta-pregnan-11,20-dione + NADP+ <=> 17alpha,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
K
Betaine_aldehyde + NADP+ + H2O <=> betaine + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
K
2-decenoyl-[acyl-carrier_protein] + NADPH <=> decanoyl-[acyl-carrier_protein] + NADP+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
K
testosterone + NADPH + H+ <=> 5beta-dihydrotestosterone + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
K
Geissoschizine + NADP+ <=> 4,21-Dehydrogeissoschizine + NADPH 1.3.1.36 geissoschizine dehydrogenase
–
K
trans-2-hexenoyl-CoA + NADPH <=> hexanoyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.44 trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
–
–
K
2-octenoyl-CoA + NADPH <=> octanoyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
–
K
trans-2-decenoyl-CoA + NADPH <=> decanoyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
K
11-deoxycorticosterone + NADPH <=> 5alpha-pregnane-21-ol-3,20-dione + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
K
trans-2-dodecenoyl-CoA + NADPH <=> lauroyl-CoA + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
–
–
K
2-tetradecenoyl-CoA + NADPH <=> myristoyl-CoA + NADP+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8 acyl-CoA dehydrogenase (NADP+)
–
–
K
folate + NADPH <=> tetrahydrofolate + NADP+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
1.5.1.34 6,7-dihydropteridine reductase
–
–
–
K
methylseleninate + NADPH <=> methylselenol + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
K
Kynurenic_acid + NADPH + O2 <=> 7,8-Dihydro-7,8-dihydroxykynurenate + NADP+ 1.14.99.2 kynurenine 7,8-hydroxylase
–
K
NADPH + vitamin_B12 <=> NADP+ + cob(I)alamin + cyanide 1.16.1.6 cyanocobalamin reductase (cyanide-eliminating)
–
K
hydroquinone + O2 + NADPH <=> Hydroxyquinol + NADP+ + H2O 1.14.13
1.14.13.7 phenol 2-monooxygenase (NADPH)
1.14.14.20 phenol 2-monooxygenase (FADH2)
–
–
–
K
3,5-dibromo-4-hydroxybenzonitrile + 2 NADPH + 2 H+ + O2 <=> 2,6-dibromo-p-hydroquinone + cyanide + 2 NADP+ + H2O 1.14.13.50 pentachlorophenol monooxygenase
–
K
2-Hydroxycyclohexan-1-one + NADPH + O2 <=> 1-Oxa-2-oxo-3-hydroxycycloheptane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
K
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine + NADPH + H+ + O2 <=> 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
3,4-dihydroxybenzoate + NADPH + O2 <=> Hydroxyquinol + NADP+ + CO2 1.13.11
1.14.13.64 4-hydroxybenzoate 1-hydroxylase
–
–
K
[Methionine_synthase]-cob(II)alamin + NADPH + S-adenosyl-L-methionine <=> [methionine_synthase]methylcob(I)alamin + S-adenosyl-L-homocysteine + NADP+ 1.16.1.8 [methionine synthase] reductase
–
acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+ <=> palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O 2.3.1
2.3.1.86 fatty-acyl-CoA synthase system
–
–
K
beta-D-glucose_6-phosphate + NADP+ <=> 6-phospho-D-glucono-1,5-lactone + NADPH 1.1.1.363 glucose-6-phosphate dehydrogenase [NAD(P)+]
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
–
K
2-acetolactate + NADPH <=> 2,3-dihydroxyisovalerate + NADP+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
11-Dehydrocorticosterone + NADPH <=> corticosterone + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.B40
–
–
K
Prostaglandin_D2 + NADPH + H+ <=> 9alpha,11beta-prostaglandin_F2 + NADP+ 1.1.1.188 prostaglandin-F synthase
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
BK
5alpha-pregnan-20alpha-ol-3-one + NADP+ <=> 5alpha-dihydroprogesterone + NADPH 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
–
K
allopregnanolone + NADPH <=> 5alpha-pregnane-3alpha,20alpha-diol + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
K
1-pyrroline-5-carboxylate + NADP+ + H2O <=> L-glutamate + NADPH 1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
–
K
p-Cresol + NADPH + O2 <=> 4-methylcatechol + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
4-methylnitrosamino-1-(3-pyridyl)-1-butanone + NADPH + H+ <=> 4-methylnitrosamino-1-(3-pyridyl)-1-butanol + NADP+ 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
K
1''-hydroxy-2''-oxopropyltetrahydropterin + NADPH <=> tetrahydrobiopterin + NADP+ 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.21 aldose reductase
–
–
K
5-hydroxyconiferaldehyde + NADPH <=> 5-hydroxyconiferyl_alcohol + NADP+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
K
caffeoyl_aldehyde + NADPH <=> caffeoyl_alcohol + NADP+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
–
K
divinyl_protochlorophyllide_a + NADPH <=> divinyl_chlorophyllide_a + NADP+ 1.3.1.33 protochlorophyllide reductase
–
K
tamoxifen + NADPH + O2 <=> tamoxifen_N-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
K
5-hydroxyferuloyl-CoA + NADPH + H+ <=> 5-hydroxyconiferaldehyde + CoA + NADP+ 1.2.1.44 cinnamoyl-CoA reductase
–
K
cortisol + NADPH <=> 11beta,17alpha,21-trihydroxy-5beta-pregnane-3,20-dione + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
–
K
(24R)-ergost-4-en-3-one + NADPH + H+ + O2 <=> (22S)-22-hydroxycampest-4-en-3-one + NADP+ + H2O 1.14.13
1.14.99.B1
–
–
K
campesterol + NADPH + H+ + O2 <=> 6-deoxocathasterone + NADP+ + H2O 1.14.13
1.14.99.B1
–
–
K
campesterol + NADPH + H+ + O2 <=> (22S)-22-hydroxycampesterol + NADP+ + H2O 1.14.13
1.14.99.B1
–
–
K
butyryl-[acyl-carrier_protein] + NADP+ <=> trans-but-2-enoyl-[acyl-carrier_protein] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
1-Indanone + NADPH + H+ + O2 <=> dihydrocoumarin + NADP+ + H2O 1.14.12
1.14.13.84 4-hydroxyacetophenone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
–
K
2-indanone + NADPH + H+ + O2 <=> 3-isochromanone + NADP+ + H2O 1.14.12
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
K
phosphonoacetaldehyde + NADPH + H+ <=> 2-hydroxyethylphosphonate + NADP+ 1.1.1.309 phosphonoacetaldehyde reductase (NADH)
1.1.99.B6
–
–
K
Caffeine + O2 + NADPH + H+ <=> theophylline + formaldehyde + NADP+ + H2O 1.13.12
1.14.13.128 7-methylxanthine demethylase
–
–
K
4-coumaryl_acetate + NADPH + H+ <=> chavicol + acetate + NADP+ 1.1.1.318 eugenol synthase
–
K
Theobromine + O2 + NADPH + H+ <=> 3-Methylxanthine + formaldehyde + NADP+ 1.13.12
1.14.13.128 7-methylxanthine demethylase
–
–
K
(S)-3-sulfolactate + NADP+ <=> 3-sulfopyruvate + NADPH + H+ 1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.338 (2R)-3-sulfolactate dehydrogenase (NADP+)
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
–
–
–
3-hydroxystearoyl-CoA + NADP+ <=> 3-oxostearoyl-CoA + NADPH + H+ 1.1.1
1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
–
MK
salicylate + NADPH + H+ + O2 <=> 2,5-Dihydroxybenzoate + NADP+ + H2O 1.14.13.172 salicylate 5-hydroxylase
–
K
D-galacturonate + NADPH + H+ <=> L-galactonate + NADP+ 1.1.1
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.203 uronate dehydrogenase
1.1.1.21 aldose reductase
1.1.1.365 D-galacturonate reductase
–
–
–
–
–
BK
biopterin + NADPH + H+ <=> dihydrobiopterin + NADP+ 1.5.1.33 pteridine reductase
–
K
2 Fe2+ + NADP+ + H+ <=> 2 Fe3+ + NADPH 1.16.1.9 ferric-chelate reductase (NADPH)
–
sitosterol + NADPH + H+ + O2 <=> stigmasterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
K
ergosta-5-enol + NADPH + H+ + O2 <=> brassicasterol + NADP+ + H2O 1.14.19.41 sterol 22-desaturase
–
K
diacetyl + NADPH + H+ <=> (R)-acetoin + NADP+ 1.1.1.B4
–
m-cresol + NADPH + H+ + O2 <=> 3-methylcatechol + NADP+ + H2O 1.14.13.7 phenol 2-monooxygenase (NADPH)
–
K
indole + NADPH + H+ + O2 <=> 3-hydroxyindole + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
1.14.16
–
–
K
1,3,8-Trihydroxynaphthalene + NADPH + H+ <=> vermelone + NADP+ 1.1.1.252 tetrahydroxynaphthalene reductase
–
D-galactose + NADP+ <=> D-galactono-1,4-lactone + NADPH + H+ 1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.376 L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase
–
–
–
–
K
5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate_6-semialdehyde + NADP+ <=> stizolobinate + NADPH + H+ 1.13.11.30 stizolobinate synthase
–
K
a_ketosteroid + O2 + NADPH + H+ <=> sterol_ester + NADP+ + H2O 1.14.13.54 ketosteroid monooxygenase
–
2-octaprenylphenol + O2 + NADPH + H+ <=> 3-(all-trans-octaprenyl)benzene-1,2-diol + H2O + NADP+ 1.14.13.240 2-polyprenylphenol 6-hydroxylase
–
M
GDP-L-fucose + NADP+ <=> GDP-4-keto-6-L-deoxygalactose + NADPH + H+ 1.1.1.271 GDP-L-fucose synthase
–
M
H+ + S-Glutathionyl-L-cysteine + NADPH <=> L-cysteine + glutathione + NADP+ 1.8.1.10 CoA-glutathione reductase
1.8.1.9 thioredoxin-disulfide reductase
1.8.4.2 protein-disulfide reductase (glutathione)
–
–
–
K
ferricytochrome_b5 + NADPH <=> ferricytochrome_b5 + NADP+ + H+ 1.6.2.5 NADPH---cytochrome-c2 reductase
–
NADPH + L-sorbose_1-phosphate + H+ <=> NADP+ + D-sorbitol_6-phosphate 1.1.1
–
MK
DELTA1-piperidine_6-carboxylate + NADP+ + H2O <=> L-2-aminoadipate + NADPH + H+ 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase
–
M
3-Hydroxypimeloyl-[acp]_methyl_ester + NADP+ <=> 3-Ketopimeloyl-[acp]_methyl_ester + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
–
MK
aminopyrrolnitrin + O2 + NADPH + H+ <=> 3-chloro-4-(3-chloro-2-nitrophenyl)pyrrole + NADP+ + H2O 1.14.13
–
MK
Episterone + NADPH + H+ <=> episterol + NADP+ 1.1.1
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
MK
choline + NADP+ <=> Betaine_aldehyde + NADPH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
–
–
K
dTDP-L-olivose + NADP+ <=> dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+ 1.1.1
–
MK
dTDP-beta-L-mycarose + NADP+ <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose + NADPH + H+ 1.1.1
–
MK
theophylline + NADPH + O2 + H+ <=> 1-Methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.179 methylxanthine N3-demethylase
–
MK
1-Methylxanthine + NADPH + O2 + H+ <=> xanthine + NADP+ + formaldehyde + H2O 1.14.13.178 methylxanthine N1-demethylase
–
MK
tryptamine + O2 + NADPH <=> N-Hydroxyl-tryptamine + H2O + NADP+ 1.14.13
–
MK
Polysulfide + Sulfide + NADP+ <=> Polysulfide + NADPH + H+ 1.8.1.19 sulfide dehydrogenase
–
UDP-2-acetamido-2,6-dideoxy-beta-L-mannose + NADP+ <=> UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose + NADPH + H+ 1.1.1
–
MK
UDP-N-acetyl-6-deoxy-alpha-D-glucosamine + NADP+ <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose + NADPH + H+ 1.1.1
–
MK
afzelechin + NADP+ + H2O <=> cis-3,4-leucopelargonidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
–
MK
aurachin_D + O2 + NADPH + H+ <=> aurachin_C + H2O + NADP+ 1.14.13
–
MK
aurachin_B + O2 + NADPH + H+ <=> Aurachin_B_epoxide + NADP+ + H2O 1.14.13
–
MK
mycinamicin_IV + O2 + NADPH + H+ <=> Mycinamicin_V + H2O + NADP+ 1.14.13
–
MK
Mycinamicin_V + O2 + NADPH + H+ <=> mycinamicin_II + H2O + NADP+ 1.14.13
–
MK
Mycinamicin_VIII + O2 + NADPH + H+ <=> Mycinamicin_VII + H2O + NADP+ 1.14.13
–
MK
mycinamicin_IV + O2 + NADPH + H+ <=> Mycinamicin_I + H2O + NADP+ 1.14.13
–
M
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ + (2S)-ethylmalonyl-CoA <=> tylactone + CoA + CO2 + H2O + NADP+ 2.3.1
–
MK
dTDP-beta-L-4-epi-vancosamine + NADP+ <=> dTDP-L-4-oxovancosamine + NADPH + H+ 1.1.1
–
MK
3-Geranylgeranylindole + O2 + NADPH + H+ <=> 10,11-Epoxy-3-geranylgeranylindole + NADP+ + H2O 1.14.13
–
MK
Emindole_SB + O2 + NADPH + H+ <=> 14,15-Epoxyemindole_SB + NADP+ + H2O 1.14.13
–
MK
4-hydroxy-2,2''-bipyrrole-5-methanol + NADP+ <=> 4-hydroxy-2,2''-bipyrrole-5-carbaldehyde + NADPH + H+ 1.1.1
–
MK
medicarpin + NADPH + H+ <=> 7,2''-dihydroxy-4''-methoxyisoflavan + NADP+ 1.1.1
1.23.1
1.3.1
–
–
–
MK
4-Hydroxyisophthalate + O2 + NADPH + H+ <=> 3,4-dihydroxybenzoate + CO2 + NADP+ + H2O 1.14.13
–
MK
Bacteriochlorophyll_b + NADP+ <=> Geranylgeranyl_bacteriochlorophyllide_b + NADPH + H+ 1.3.1.111 geranylgeranyl-bacteriochlorophyllide a reductase
–
K
norbelladine + NADP+ <=> Norcraugsodine + NADPH + H+ 1.4.1
–
MK
7,8-dihydrofolate + NADP+ <=> folate + NADPH + H+ 1.5.1.3 dihydrofolate reductase
1.5.1.33 pteridine reductase
–
–
K
5,10-methylenetetrahydromethanopterin + NADP+ <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH 1.5.1
–
MK
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + NADP+ <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH 1.3.1
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
–
MK
(Z)-phenylacetaldoxime + O2 + L-cysteine + NADPH + H+ <=> S-(Phenylacetothiohydroximoyl)-L-cysteine + H2O + NADP+ 1.14
–
5alpha-campestan-3-one + NADP+ <=> H+ + (24R)-ergost-4-en-3-one + NADPH 1.3.1
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
–
MK
Dihydrogeranylgeranyl_diphosphate + NADP+ <=> geranylgeranyl_diphosphate + NADPH + H+ 1.3.1
–
M
Tetrahydrogeranylgeranyl_diphosphate + NADP+ <=> Dihydrogeranylgeranyl_diphosphate + NADPH + H+ 1.3.1
–
M
phytyl_diphosphate + NADP+ <=> Tetrahydrogeranylgeranyl_diphosphate + NADPH + H+ 1.3.1
–
M
sinapaldehyde + NADP+ + H2O <=> H+ + Sinapic_acid + NADPH 1.2.1
1.2.1.68 coniferyl-aldehyde dehydrogenase
–
–
MK
H+ + 2-nitrobenzoate + NADPH <=> o-Hydroxylaminobenzoate + NADP+ + H2O 1.7.1
–
MK
H+ + Clavulanate-9-aldehyde + NADPH <=> clavulanic_acid + NADP+ not assigned
 –
MK
H+ + 6-propyl-2,3,4,5-tetrahydropyridine + NADPH <=> Coniine + NADP+ 1.5.1
–
M
CDP-4-dehydro-3,6-dideoxy-D-glucose_epimer + NADPH + H+ <=> CDP-ascarylose + NADP+ 1.1.1
1.1.1.M47
–
–
MK
(-)-limonene + NADPH + H+ + O2 <=> (4S)-limonene-1,2-epoxide + NADP+ + H2O 1.14.13.107 limonene 1,2-monooxygenase
–
MK
(1S,4R)-1-hydroxy-2-oxolimonene + NADPH + H+ + O2 <=> (4R)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(1R,4S)-1-hydroxy-2-oxolimonene + NADPH + H+ + O2 <=> (4S)-7-Hydroxy-4-isopropenyl-7-methyl-2-oxo-oxepanone + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(1R,4S)-isodihydrocarvone + NADPH + H+ + O2 <=> 4-isopropenyl-7-methyloxepan-2-one + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(-)-dihydrocarvone + O2 + NADPH + H+ <=> (3S,6S)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
(1R,4S)-isodihydrocarvone + O2 + NADPH + H+ <=> (3S,6R)-6-Isopropenyl-3-methyl-2-oxo-oxepanone + H2O + NADP+ 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
MK
H+ + 1'-hydroxyversicolorone + NADPH + O2 <=> versiconal_hemiacetal_acetate + NADP+ + H2O not assigned
 –
MK
H+ + versicolorone + NADPH + O2 <=> versiconol_acetate + NADP+ + H2O not assigned
 –
MK
hexanoyl-[acyl-carrier_protein] + NADP+ <=> trans-Hex-2-enoyl-[acp] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
(3R)-3-hydroxyoctanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxooctanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
MK
octanoyl-[acyl-carrier_protein] + NADP+ <=> 2-octenoyl-[acyl-carrier_protein] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
(3R)-3-hydroxydecanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxodecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
MK
(3R)-3-hydroxymyristoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxotetradecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
MK
tetradecanoyl-[acyl-carrier_protein] + NADP+ <=> trans-Tetradec-2-enoyl-[acp] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
MK
palmitoyl-[acyl-carrier_protein] + NADP+ <=> trans-Hexadec-2-enoyl-[acp] + NADPH + H+ 1.3.1
1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
–
–
–
–
K
stearoyl-CoA + NADP+ <=> trans-2-octadecenoyl-CoA + NADPH + H+ 1.3.1
1.3.1.93 very-long-chain enoyl-CoA reductase
–
–
MK
gallocatechin + NADP+ + H2O <=> 3,4-cis-leucodelphinidin + NADPH + H+ 1.17.1.3 leucoanthocyanidin reductase
–
MK
2-Undecylpyrrole + NADP+ + H2O <=> 4-Keto-2-undecylpyrroline + NADPH + H+ 1.17.1
–
MK
trans-4-hydroxy-L-proline + NADP+ <=> NADPH + L-1-pyrroline-3-hydroxy-5-carboxylate + H+ 1.5.1.2 pyrroline-5-carboxylate reductase
–
K
alpha-tetralone + NADPH + H+ <=> alpha-tetralol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
1.1.1.B57
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
formaldehyde + NADPH <=> methanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.244 methanol dehydrogenase
1.1.1.263 1,5-anhydro-D-fructose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
propionaldehyde + NADPH <=> 1-propanol + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.191 indole-3-acetaldehyde reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.80 isopropanol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
–
–
2-methylbutanal + NADPH <=> 2-methylbutanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
pentanal + NADPH <=> 1-Pentanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
hexanal + NADPH + H+ <=> 1-Hexanol + NADP+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
Heptanal + NADPH <=> 1-Heptanol + NADP+ 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
–
–
4-methoxybenzaldehyde + NADPH <=> 4-methoxybenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
octanal + NADPH + H+ <=> 1-Octanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.265 3-methylbutanal reductase
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.6.2.4 NADPH---hemoprotein reductase
–
–
–
–
–
–
–
–
–
–
Pyridine-3-aldehyde + NADPH <=> 3-Pyridylcarbinol + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.265 3-methylbutanal reductase
1.1.1.33 mevaldate reductase (NADPH)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.65 pyridoxine 4-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
D-gluconate + NADPH <=> D-glucose + NADP+ 1.1.1.265 3-methylbutanal reductase
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
–
–
Quinine + NADPH + O2 <=> 3-hydroxyquinine + NADP+ + H2O 1.14.14.55 quinine 3-monooxygenase
–
laurate + NADPH + H+ + O2 <=> 12-hydroxydodecanoate + NADP+ + H2O 1.14.14.80 long-chain fatty acid omega-monooxygenase
1.14.15.3 alkane 1-monooxygenase
–
–
progesterone + NADPH + O2 <=> 11-deoxycorticosterone + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.14.16 steroid 21-monooxygenase
–
–
1-Acenaphthenol + NADP+ <=> 1-Acenaphthenone + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
1.10.1.1 trans-acenaphthene-1,2-diol dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
(S)-indan-1-ol + NADP+ <=> 1-Indanone + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
2-Cyclohexen-1-ol + NADP+ <=> 2-cyclohexen-1-one + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
3-Nitrobenzaldehyde + NADPH <=> 3-Nitrobenzyl_alcohol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.274 2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
2-nitrobenzaldehyde + NADPH <=> 2-nitrobenzyl_alcohol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.283 methylglyoxal reductase (NADPH)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.65 pyridoxine 4-dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
–
–
diacetyl + NADPH <=> 2,3-Butanediol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.21 aldose reductase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
5beta-Pregnan-3alpha-ol-20-one + NADPH + H+ <=> 5beta-pregnane-3alpha,20alpha-diol + NADP+ 1.1.1.112 indanol dehydrogenase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
–
–
Cyclohexanol + NADP+ <=> cyclohexanone + NADPH 1.1.1.112 indanol dehydrogenase
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.53 3alpha(or 20beta)-hydroxysteroid dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
–
–
–
–
2-deoxy-D-glucose + NADP+ <=> 2-deoxy-D-glucono-1,5-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.121 aldose 1-dehydrogenase (NAD+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
dTDP-6-deoxy-L-lyxo-4-hexulose + NADPH <=> dTDP-L-rhamnose + NADP+ 1.1.1.133 dTDP-4-dehydrorhamnose reductase
–
Epitestosterone + NADP+ <=> 4-androstene-3,17-dione + NADPH 1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
17alpha-estradiol_3-glucuronide + NADP+ <=> estrone_3-glucuronide + NADPH 1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
–
(5beta,20R)-20-hydroxypregnan-3-one + NADP+ <=> 5beta-pregnane-3,20-dione + NADPH 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
pregn-4-ene-3,20,21-trione + NADPH <=> 11-deoxycorticosterone + NADP+ 1.1.1.151 21-hydroxysteroid dehydrogenase (NADP+)
–
1,2-propanediol + NADP+ <=> Hydroxyacetone + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
–
2,3-Butanediol + NADP+ <=> acetoin + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.156 glycerol 2-dehydrogenase (NADP+)
1.1.1.162 erythrulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.4 (R,R)-butanediol dehydrogenase
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
–
–
–
chenodeoxycholic_acid + NADP+ <=> 7-ketolithocholic_acid + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.159 7alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
Methyl_pyruvate + NADPH <=> 2-Methyllactate + NADP+ 1.1.1.162 erythrulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
ethyl_pyruvate + NADPH <=> ethyl_lactate + NADP+ 1.1.1.162 erythrulose reductase
1.1.1.184 carbonyl reductase (NADPH)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
citronellol + NADP+ <=> citronellal + NADPH 1.1.1.183 geraniol dehydrogenase (NADP+)
1.1.1.216 farnesol dehydrogenase (NADP+)
–
–
4-Nitroacetophenone + NADPH <=> 1-(4-nitrophenyl)ethanol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
–
–
–
–
–
–
–
4-methylbenzaldehyde + NADPH <=> 4-methylbenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
3-methylbenzaldehyde + NADPH <=> 3-methylbenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
D-Lactaldehyde + NADPH + H+ <=> 1,2-propanediol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
4-carboxybenzaldehyde + NADPH <=> 4-carboxybenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
4-cyanobenzaldehyde + NADPH <=> 4-cyanobenzylalcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.33 mevaldate reductase (NADPH)
–
–
–
3-Formyl-benzonitrile + NADPH <=> 3-cyanobenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
4-methylbenzaldehyde + NADPH <=> Toluene + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
4-Fluorobenzaldehyde + NADPH + H+ <=> 4-fluorobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
3-Fluorobenzaldehyde + NADPH + H+ <=> 3-fluorobenzyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
4-Chlorobenzaldehyde + NADPH + H+ <=> 4-Chlorobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
–
–
3-Chlorobenzaldehyde + NADPH + H+ <=> 3-Chlorobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
p-hydroxyphenylglycolaldehyde + NADPH <=> 4-(2-hydroxyethyl)phenol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
4-hydroxyphenylacetaldehyde + NADPH + H+ <=> 4-(2-hydroxyethyl)phenol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
3-Methoxybenzaldehyde + NADPH + H+ <=> 3-anisyl_alcohol + NADP+ 1.1.1.195 cinnamyl-alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
–
–
–
Pyridine-4-aldehyde + NADPH <=> 4-pyridinemethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.65 pyridoxine 4-dehydrogenase
–
–
–
–
–
2-butanol + NADP+ <=> 2-butanone + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.4 (R,R)-butanediol dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.80 isopropanol dehydrogenase (NADP+)
–
–
–
–
–
–
2-Pentanol + NADP+ <=> 2-Pentanone + NADPH 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.80 isopropanol dehydrogenase (NADP+)
–
–
–
–
–
hexadecanol + NADP+ <=> hexadecanal + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
1.6.2.4 NADPH---hemoprotein reductase
–
–
octadecanal + NADPH + H+ <=> octadecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
decanal + NADPH + H+ <=> Decanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.216 farnesol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
dodecanal + NADPH + H+ <=> Dodecanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
13-cis-retinal + NADPH <=> 13-cis-retinol + NADP+ 1.1.1.105 all-trans-retinol dehydrogenase (NAD+)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.300 NADP-retinol dehydrogenase
–
–
–
pyruvate + NADPH <=> Lactate + NADP+ 1.1.1.110 aromatic 2-oxoacid reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.215 gluconate 2-dehydrogenase
1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.28 D-lactate dehydrogenase
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
–
–
–
–
–
–
acetyl-CoA + NADPH <=> acetaldehyde + CoA + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.2.1.10 acetaldehyde dehydrogenase (acetylating)
1.2.1.87 propanal dehydrogenase (CoA-propanoylating)
–
–
–
Salicylaldehyde + NADPH <=> salicyl_alcohol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
cis-benzene_dihydrodiol + NADP+ <=> catechol + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
5beta-pregnane-3alpha,20alpha-diol + NADP+ <=> 5beta-pregnan-20alpha-ol-3-one + NADPH 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
5beta-androstane-3alpha,17beta-diol + NADP+ <=> 5beta-androstane-3alpha,17beta-diol + NADPH 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
–
–
–
–
acenaphthenequinone + NADPH <=> acenaphthenehydroquinone + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
5alpha-androstane-3alpha,17beta-diol + NADP+ <=> androsterone + NADPH 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
–
D-erythrose + NADPH <=> erythritol + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.21 aldose reductase
1.1.1.307 D-xylose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
D-ribose + NADPH <=> ribitol + NADP+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.19 glucuronate reductase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
–
–
–
–
L-Xylose + NADPH <=> xylitol + NADP+ 1.1.1.21 aldose reductase
–
D-mannose + NADPH <=> D-mannitol + NADP+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.289 sorbose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
D-arabinose + NADPH <=> D-arabitol + NADP+ 1.1.1.138 mannitol 2-dehydrogenase (NADP+)
1.1.1.19 glucuronate reductase
1.1.1.21 aldose reductase
1.1.1.307 D-xylose reductase
–
–
–
–
Dihydrocodeine + NADP+ <=> dihydrocodeinone + NADPH 1.1.1.218 morphine 6-dehydrogenase
–
cyclohexene-2-ol + NADP+ <=> 2-cyclohexen-1-one + NADPH 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.218 morphine 6-dehydrogenase
–
–
pyruvate + NADPH + H+ <=> L-lactate + NADP+ 1.1.1.1 alcohol dehydrogenase
1.1.1.27 L-lactate dehydrogenase
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
–
–
–
–
5alpha-androstane-3,17-dione + NADPH <=> epiandrosterone + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
–
–
–
5alpha-dihydrotestosterone + NADP+ <=> 5alpha-androstane-3,17-dione + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
–
–
–
5alpha-Androstane-3beta,17beta-diol + NADP+ <=> epiandrosterone + NADPH 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
5beta-androstane-3alpha,17beta-diol + NADP+ <=> 5beta-androstane-3,17-dione + NADPH 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
4-Hydroxybenzyl_alcohol + NADP+ <=> 4-hydroxybenzaldehyde + NADPH 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
1.1.1.97 3-hydroxybenzyl-alcohol dehydrogenase
–
–
–
phosphite + H2O + NADP+ <=> phosphate + NADPH + H+ 1.20.1.1 phosphonate dehydrogenase
–
D-glyceraldehyde_3-phosphate + arsenate + NADP+ <=> 3-phospho-D-glyceroyl_arsenate + NADPH 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
–
–
–
3-deoxyglucosone + NADP+ + H2O <=> 2-dehydro-3-deoxy-D-gluconate + NADPH + H+ 1.2.1.49 2-oxoaldehyde dehydrogenase (NADP+)
–
2 ferricytochrome_c + NADPH <=> 2 ferricytochrome_c + NADP+ + H+ 1.16.1.8 [methionine synthase] reductase
1.18.1.2 ferredoxin---NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
1.6.2.4 NADPH---hemoprotein reductase
1.6.2.6 leghemoglobin reductase
1.7.1.3 nitrate reductase (NADPH)
1.8.1.2 assimilatory sulfite reductase (NADPH)
–
–
–
–
–
–
–
1,4-Naphthoquinone + NADPH <=> NADP+ + 1,4-naphthoquinol 1.1.1.328 nicotine blue oxidoreductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
1.7.1.6 azobenzene reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
1,2-naphthoquinone + NADPH <=> NADP+ + 1,2-dihydroxynaphthalene 1.1.1.2 alcohol dehydrogenase (NADP+)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
–
–
–
–
2-Chlorobenzaldehyde + NADPH + H+ <=> 2-chlorobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
2 ferricyanide + NADPH <=> 2 ferrocyanide + NADP+ + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.12.1.2 hydrogen dehydrogenase
1.14.13.39 nitric-oxide synthase (NADPH)
1.14.14.1 unspecific monooxygenase
1.16.1.7 ferric-chelate reductase (NADH)
1.16.1.9 ferric-chelate reductase (NADPH)
1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.6 adrenodoxin-NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
1.4.1.13 glutamate synthase (NADPH)
1.6.2.2 cytochrome-b5 reductase
1.6.2.4 NADPH---hemoprotein reductase
1.6.2.5 NADPH---cytochrome-c2 reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.4 monodehydroascorbate reductase (NADH)
1.7.1.3 nitrate reductase (NADPH)
1.7.1.6 azobenzene reductase
1.8.1.7 glutathione-disulfide reductase
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
crotonaldehyde + NADPH <=> 2-Buten-1-ol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
Nonanal + NADPH <=> 1-nonanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.21 aldose reductase
1.1.1.300 NADP-retinol dehydrogenase
1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
–
–
ethyl_2-chloro-3-oxobutanoate + NADPH + H+ <=> ethyl_2-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
ethyl_acetoacetate + NADPH <=> ethyl_3-hydroxybutanoate + NADP+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
–
–
–
–
–
prostaglandin_E2 + NADP+ <=> 15-ketoprostaglandin_E2 + NADPH + H+ 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+)
1.1.1.189 prostaglandin-E2 9-reductase
1.1.1.196 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)
1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
–
–
–
–
–
–
4-methylcyclohexanone + NADPH <=> 4-methylcyclohexanol + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
3-methylcyclohexanone + NADPH <=> 3-Methylcyclohexanol + NADP+ 1.1.1.206 tropinone reductase I
1.1.1.236 tropinone reductase II
–
–
4-nitrobenzaldehyde + NADP+ <=> 4-nitrobenzoate + NADPH 1.1.1.231 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
–
methyl_p-tolyl_sulfide + NADPH + O2 <=> methyl_4-tolyl_sulfoxide + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
–
–
–
formaldehyde + NADP+ + H2O <=> formate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
Nonanal + NADP+ + H2O <=> Nonanoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
dodecanal + NADP+ + H2O <=> laurate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
glycolaldehyde + NADP+ + H2O <=> glycolate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.21 glycolaldehyde dehydrogenase
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
–
–
–
–
–
–
–
testosterone + NADPH + H+ <=> 4-androsten-3alpha,17beta-diol + NADP+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
–
5beta-dihydrotestosterone + NADPH <=> 5beta-androstane-3beta,17beta-diol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
–
5beta-androstane-3,17-dione + NADPH <=> 5beta-androstan-3beta-ol-17-one + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
–
–
–
testosterone + NADPH + H+ <=> 4-Androsten-3beta,17beta-diol + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
–
–
4-androstene-3,17-dione + NADPH + H+ <=> dehydroepiandrosterone + NADP+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
–
menadione + NADPH <=> menadiol + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.328 nicotine blue oxidoreductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.4.1.13 glutamate synthase (NADPH)
1.5.1.20 methylenetetrahydrofolate reductase [NAD(P)H]
1.6.2.4 NADPH---hemoprotein reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.12 demethylphylloquinone reductase
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.8.1.15 mycothione reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
3-bromobenzaldehyde + NADPH + H+ <=> 3-bromobenzyl_alcohol + NADP+ 1.1.1.21 aldose reductase
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
4-bromobenzaldehyde + NADPH + H+ <=> 4-bromobenzyl_alcohol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.21 aldose reductase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
1.1.1.91 aryl-alcohol dehydrogenase (NADP+)
–
–
–
–
Crotonyl-N-acetyl-cysteamine + NADPH <=> Butyryl-N-acetyl-cysteamine + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
–
–
–
trans-2-octenoyl-N-acetylcysteamine + NADPH <=> octanoyl-N-acetylcysteamine + NADP+ 1.3.1.10 enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104 enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
–
–
–
dihydrodipicolinate + NADPH <=> tetrahydrodipicolinate + NADP+ 1.17.1.8 4-hydroxy-tetrahydrodipicolinate reductase
–
crotonaldehyde + NADPH <=> Butyraldehyde + NADP+ 1.3.1.27 2-hexadecenal reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
–
–
–
trans-2-hexenal + NADPH <=> hexanal + NADP+ 1.3.1.27 2-hexadecenal reductase
1.3.1.31 2-enoate reductase
1.3.1.42 12-oxophytodienoate reductase
1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
1.6.99.1 NADPH dehydrogenase
–
–
–
–
–
–
–
3-penten-2-one + NADPH <=> 2-Pentanone + NADP+ 1.3.1.48 13,14-dehydro-15-oxoprostaglandin 13-reductase
1.3.1.74 2-alkenal reductase [NAD(P)+]
1.6.5.5 NADPH:quinone reductase
–
–
–
10-formyl-5,8-dideazafolate + NADP+ + H2O <=> 5,8-Dideazafolate + CO2 + NADPH + H+ 1.5.1.6 formyltetrahydrofolate dehydrogenase
–
NADPH + 2,6-dichlorophenolindophenol <=> NADP+ + reduced_2,6-dichlorophenolindophenol 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.328 nicotine blue oxidoreductase
1.12.1.2 hydrogen dehydrogenase
1.17.1.4 xanthine dehydrogenase
1.18.1.2 ferredoxin---NADP+ reductase
1.18.1.3 ferredoxin---NAD+ reductase
1.18.1.6 adrenodoxin-NADP+ reductase
1.19.1.1 flavodoxin---NADP+ reductase
1.5.1.30 flavin reductase (NADPH)
1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.2.4 NADPH---hemoprotein reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.7.1.6 azobenzene reductase
1.8.1.4 dihydrolipoyl dehydrogenase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
NADPH + thio-NAD+ + H+ <=> NADP+ + thio-NADH + H+ 1.6.1.1 NAD(P)+ transhydrogenase (Si-specific)
1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
7.1.1.1 proton-translocating NAD(P)+ transhydrogenase
–
–
–
–
NADPH + H+ + ubiquinone <=> NADP+ + ubiquinol 1.1.1.184 carbonyl reductase (NADPH)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.11 NADH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.4 dihydrolipoyl dehydrogenase
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
–
–
–
–
–
–
NADPH + H+ + duroquinone <=> NADP+ + durohydroquinone 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
NADPH + 9,10-phenanthrenequinone <=> NADP+ + 9,10-phenanthrenequinol 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.188 prostaglandin-F synthase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.21 aldose reductase
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.263 1,5-anhydro-D-fructose reductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.7.1.6 azobenzene reductase
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
5-hydroxy-1,4-naphthoquinone + NADPH <=> 5-hydroxy-1,4-naphthoquinol + NADP+ 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.8.1.15 mycothione reductase
1.8.1.8 protein-disulfide reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
5,5''-dithiobis(2-nitrobenzoic_acid) + NADPH <=> 5-thio-2-nitrobenzoate + NADP+ 1.8.1.15 mycothione reductase
1.8.1.7 glutathione-disulfide reductase
1.8.1.8 protein-disulfide reductase
1.8.1.9 thioredoxin-disulfide reductase
1.8.1.B1
–
–
–
–
–
Butyraldehyde + NADP+ + H2O <=> Butyrate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
–
–
–
–
pentanal + NADP+ <=> pentanoate + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
–
–
–
–
–
Isovaleraldehyde + NADP+ + H2O <=> Isovalerate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
–
hexanal + NADP+ <=> hexanoate + NADPH 1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
–
–
–
–
–
Heptanal + NADP+ <=> Heptanoate + NADPH 1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.77 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase (NADP+)
–
–
–
–
–
octanal + NADP+ + H2O <=> Octanoate + NADPH + H+ 1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
–
–
decanal + NADP+ <=> Decanoate + NADPH 1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
–
Undecanal + NADP+ <=> Undecanoate + NADPH 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
–
–
–
–
squalene + NADPH + O2 <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP+ + H2O 1.14.14.17 squalene monooxygenase
–
testosterone + NADPH + O2 <=> 6beta-hydroxytestosterone + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.14.25 cholesterol 24-hydroxylase
1.14.14.55 quinine 3-monooxygenase
1.14.14.57 taurochenodeoxycholate 6alpha-hydroxylase
1.14.99.4 progesterone monooxygenase
–
–
–
–
–
tabersonine + NADPH + H+ + O2 <=> 16-hydroxytabersonine + NADP+ + H2O 1.14.14.103 tabersonine 16-hydroxylase
–
Pentachlorophenol + NADPH + O2 <=> tetrachlorohydroquinone + NADP+ + Cl- 1.14.13.50 pentachlorophenol monooxygenase
–
thioanisole + NADPH + H+ + O2 <=> (R)-methyl_phenyl_sulfoxide + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
1.14.13.8 flavin-containing monooxygenase
1.14.13.84 4-hydroxyacetophenone monooxygenase
1.14.13.92 phenylacetone monooxygenase
–
–
–
–
25-hydroxyvitamin_D3 + NADPH + O2 <=> 1alpha,25-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
1.14.15.15 cholestanetriol 26-monooxygenase
1.14.15.18 calcidiol 1-monooxygenase
–
–
–
B
quinonoid_2-amino-4-hydroxy-6,7-dimethyldihydropteridine + NADPH <=> 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
hypoxanthine + NADP+ + H2O <=> xanthine + NADPH 1.17.1.4 xanthine dehydrogenase
–
acetophenone + NADPH + H+ + O2 <=> phenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-hydroxypropiophenone + NADPH + H+ + O2 <=> 4-Hydroxyhydratropate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-methylacetophenone + NADPH + H+ + O2 <=> p-tolyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-methoxyacetophenone + NADPH + H+ + O2 <=> 4-methoxy_phenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-fluoroacetophenone + NADPH + H+ + O2 <=> 4-Fluorophenylacetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
4-hydroxy-3-methylacetophenone + NADPH + H+ + O2 <=> 4-hydroxy-3-methylphenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
2-hydroxyacetophenone + NADPH + H+ + O2 <=> 2-hydroxyphenyl_acetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
3-hydroxyacetophenone + NADPH + H+ + O2 <=> 3-hydroxyphenylacetate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
benzaldehyde + NADPH + H+ + O2 <=> phenyl_formate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
propiophenone + NADPH + H+ + O2 <=> phenylpropionate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
butyrophenone + NADPH + H+ + O2 <=> phenyl_butyrate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
isobutyrophenone + NADPH + H+ + O2 <=> phenyl_isobutyrate + NADP+ + H2O 1.14.13.84 4-hydroxyacetophenone monooxygenase
–
5beta-androstane-3alpha,17beta-diol + NADP+ <=> 5beta-androstane-3alpha-ol-17-one + NADPH 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.62 17beta-estradiol 17-dehydrogenase
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
heme + 2 NADPH + 2 H+ + 2 O2 <=> Biliverdin + Fe2+ + CO + 2 NADP+ + H2O 1.14.14.18 heme oxygenase (biliverdin-producing)
–
7beta-hydroxycholesterol + NADP+ <=> 7-oxocholesterol + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)
1.1.1.B40
–
–
–
ethyl_4-chloro-3-oxobutanoate + NADPH + H+ <=> ethyl_(S)-4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.B3
1.1.1.B51
–
–
–
–
3-methyl-2-oxopentanoate + NADPH <=> 2-hydroxy-3-methylpentanoate + NADP+ 1.1.1.169 2-dehydropantoate 2-reductase
–
7alpha-hydroxycholesterol + NADP+ <=> 7-oxocholesterol + NADPH 1.1.1.146 11beta-hydroxysteroid dehydrogenase
–
acetophenone + NADPH <=> (R)-1-phenylethanol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
Chloroacetaldehyde + NADP+ + H2O <=> Chloroacetate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
–
D-ribulose + NADPH <=> ribitol + NADP+ 1.1.1.10 L-xylulose reductase
1.1.1.405 ribitol-5-phosphate 2-dehydrogenase (NADP+)
–
–
D-threose + NADPH <=> D-threitol + NADP+ 1.1.1.10 L-xylulose reductase
–
glutathione-4-oxonon-2-enal + NADPH <=> glutathione-4-oxononanal + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
NADP+ + H2O <=> 2'-phospho-ADP-ribose + nicotinamide 3.2.2.5 NAD+ glycohydrolase
3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
–
–
pyridoxal + NADP+ <=> 4-Pyridoxolactone + NADPH + H+ 1.1.1.107 pyridoxal 4-dehydrogenase
–
tibolone + NADPH <=> 3alpha-tibolone + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
tibolone + NADPH <=> 3beta-hydroxytibolone + NADP+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
trans-2-nonenal + NADPH + H+ <=> trans-2-nonen-1-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
7alpha-hydroxy-4-cholesten-3-one + NADPH + H+ + O2 <=> 7alpha,12alpha-dihydroxy-4-cholesten-3-one + NADP+ + H2O 1.14.18.8 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
–
2,5-bis(aziridin-1-yl)cyclohexa-2,5-diene-1,4-dione + NADPH <=> 2,5-diaziridinyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.9 thioredoxin-disulfide reductase
–
–
2,5-bis(aziridin-1-yl)-3-(hydroxymethyl)-6-methylcyclohexa-2,5-diene-1,4-dione + NADPH <=> 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.9 thioredoxin-disulfide reductase
–
–
2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinone + NADPH <=> 2,5-dimethyl-3,6-diaziridinyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.8.1.9 thioredoxin-disulfide reductase
–
–
2,6-dimethyl-1,4-benzoquinone + NADPH <=> 2,6-dimethyl-1,4-benzoquinol + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.8.1.15 mycothione reductase
1.8.1.8 protein-disulfide reductase
–
–
–
–
2-dodecanone + NADPH + O2 <=> nonyl_acetate + methyl_decanoate + NADP+ + H2O 1.14.13.92 phenylacetone monooxygenase
–
cytochrome_c + NADPH <=> ferricytochrome_c + NADP+ 1.1.1.404 tetrachlorobenzoquinone reductase
1.14.14.1 unspecific monooxygenase
1.18.1.2 ferredoxin---NADP+ reductase
1.6.2.2 cytochrome-b5 reductase
1.6.2.4 NADPH---hemoprotein reductase
1.6.5.10 NADPH dehydrogenase (quinone)
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
2,5-dibromo-3-methyl-6-isopropylbenzoquinone + NADPH <=> 2,5-dibromo-3-methyl-6-isopropyl-4-benzoquinol + NADP+ 1.18.1.2 ferredoxin---NADP+ reductase
1.6.5.10 NADPH dehydrogenase (quinone)
–
–
fenthion + NADPH + O2 <=> (rac)_fenthion_sulfoxide + NADP+ 1.14.13.8 flavin-containing monooxygenase
1.14.14.1 unspecific monooxygenase
–
–
NADPH + H+ + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> NADP+ + reduced_coenzyme_Q0 1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
–
reduced_ferredoxin_I + NADP+ <=> oxidized_ferredoxin_I + NADPH 1.18.1.2 ferredoxin---NADP+ reductase
–
4-oxonon-2-enal + NADPH + H+ <=> 1-hydroxynon-2-en-4-one + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
4-oxonon-2-enal + NADPH + H+ <=> 4-hydroxy-2-nonenal + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
1.1.1.64 testosterone 17beta-dehydrogenase (NADP+)
–
–
–
–
4-oxonon-2-enal + NADPH + H+ <=> 4-oxononanal + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
daunorubicin + NADPH + H+ <=> 13-dihydrodaunorubicin + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
–
–
–
doxorubicin + NADPH + H+ <=> doxorubicinol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
glutathione-4-oxonon-2-enal + NADPH + H+ <=> glutathione-4-hydroxynon-2-enal + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
androstanedione + NADPH <=> 5alpha-androstane-3-one-17alpha-ol + NADP+ 1.1.1.148 estradiol 17alpha-dehydrogenase
1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
–
–
androsterone + NADPH <=> 5alpha-androstane-3alpha,17alpha-diol + NADP+ 1.1.1.148 estradiol 17alpha-dehydrogenase
–
hydroxycobalamin + NADPH + H+ <=> Cobalamin + NADP+ 1.16.1.3 aquacobalamin reductase
1.16.1.5 aquacobalamin reductase (NADPH)
–
–
cholesterol + NADPH + O2 <=> (24S)-24-hydroxycholesterol + NADP+ + H2O 1.14.14.25 cholesterol 24-hydroxylase
–
L-methionine + NADPH + O2 <=> methionine_sulfoxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2,4,6-trinitrotoluene + NADPH_+ <=> 2,4,6-trinitrotoluene + NADP+ 1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.99.1 NADPH dehydrogenase
–
–
2-acetylpyridine + NADPH <=> (S)-1-(2-pyridyl)ethanol + NADP+ 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.62 17beta-estradiol 17-dehydrogenase
–
–
3-hydroxy-4-methylbenzoate + NADPH + O2 <=> 4-Methylgentisate + NADP+ + H2O 1.14.13.24 3-hydroxybenzoate 6-monooxygenase
–
4-hydroxy-2-nonenal + NADP+ + H2O <=> (2E)-4-hydroxynon-2-enoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
Benzydamine + NADPH + O2 <=> benzydamine_N-oxide + NADP+ + H2O 1.14.13.148 trimethylamine monooxygenase
1.14.13.8 flavin-containing monooxygenase
–
–
ethylenethiourea + NADPH + O2 <=> ethylenethiourea_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
NADPH + H+ + duroquinone <=> NADP+ + duroquinol 1.1.1.188 prostaglandin-F synthase
1.1.1.328 nicotine blue oxidoreductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
–
–
–
–
–
S-Benzyl-L-cysteine + NADPH + O2 <=> petiveriin + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
trans-2-hexenal + NADP+ + H2O <=> trans-2-hexenoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
trans-2-nonenal + NADP+ + H2O <=> (2E)-non-2-enoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
trans-2-octenal + NADP+ + H2O <=> (2E)-oct-2-enoate + NADPH + H+ 1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
–
–
(1R,4S)-1-hydroxy-2-oxolimonene + NADPH + H+ + O2 <=> 3-isopropenyl-6-oxoheptanoate + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
(1S,4R)-1-hydroxy-2-oxolimonene + NADPH + H+ + O2 <=> 3-isopropenyl-6-oxoheptanoate + NADP+ + H2O 1.14.13.105 monocyclic monoterpene ketone monooxygenase
–
2-trans,4-trans-decadienoyl-CoA + NADPH <=> trans-3-decenoyl-CoA + NADP+ 1.3.1.34 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]
–
4-benzoylpyridine + NADPH <=> phenyl-4-pyridylmethanol + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
dehydroepiandrosterone + NADP+ <=> 5-androstene-3,17-dione + NADPH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
1.1.1.146 11beta-hydroxysteroid dehydrogenase
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
–
–
–
coenzyme_Q10 + NADPH <=> ubiquinol + NADP+ 1.1.1.188 prostaglandin-F synthase
1.8.1.4 dihydrolipoyl dehydrogenase
–
–
benzoyl-CoA + NADPH + H+ + O2 <=> 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP+ 1.14.13.208 benzoyl-CoA 2,3-epoxidase
–
vitamin_D3 + NADPH + O2 <=> 25-hydroxyvitamin_D3 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
1.14.15.15 cholestanetriol 26-monooxygenase
1.14.15.18 calcidiol 1-monooxygenase
–
–
–
B
2 Plumbagin + NADPH + H+ <=> Plumbagin + NADP+ 1.6.5.5 NADPH:quinone reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
NADPH + iodonitrotetrazolium_chloride <=> NADP+ + reduced_iodonitrotetrazolium_chloride 1.18.1.2 ferredoxin---NADP+ reductase
1.4.1.13 glutamate synthase (NADPH)
–
–
Methimazole + NADPH + H+ + O2 <=> methimazole_S-oxide + NADP+ + H2O 1.14.13.8 flavin-containing monooxygenase
–
2-Methylpentanal + NADPH + H+ <=> 2-Methyl-1-pentanol + NADP+ 1.1.1.21 aldose reductase
1.1.1.72 glycerol dehydrogenase (NADP+)
–
–
L-gulonate + NADP+ <=> 3-dehydro-L-gulonate + NADPH + H+ 1.1.1.45 L-gulonate 3-dehydrogenase
–
25-hydroxyvitamin_D3 + NADPH + H+ + O2 <=> secalciferol + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
1alpha-hydroxyvitamin_D2 + O2 + NADPH + H+ <=> 1alpha,25-dihydroxyvitamin_D2 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
1.14.15.15 cholestanetriol 26-monooxygenase
–
–
H2O + O2 + NADPH + H+ <=> 1alpha,25-dihydroxyvitamin_D3 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
1.14.15.15 cholestanetriol 26-monooxygenase
–
–
bufuralol + O2 + NADPH + H+ <=> 1''-hydroxybufuralol + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
1.14.14.24 vitamin D 25-hydroxylase
1.14.14.25 cholesterol 24-hydroxylase
–
–
–
vitamin_D2 + O2 + NADPH + H+ <=> 25-hydroxyvitamin_D2 + NADP+ + H2O 1.14.14.24 vitamin D 25-hydroxylase
–
D-galactose + NADP+ + H2O <=> D-galactonate + NADPH + 2 H+ 1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
–
–
(R)-2-butanol + NADP+ <=> 2-butanone + NADPH + H+ 1.1.1.1 alcohol dehydrogenase
1.1.1.184 carbonyl reductase (NADPH)
1.1.1.2 alcohol dehydrogenase (NADP+)
–
–
–
androstanediol + NADP+ <=> 5alpha-dihydrotestosterone + NADPH + H+ 1.1.1.184 carbonyl reductase (NADPH)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
–
–
2-cyclohexen-1-one + NADPH + H+ <=> cyclohexanone + NADP+ 1.3.1.3 Delta4-3-oxosteroid 5beta-reductase
1.6.99.1 NADPH dehydrogenase
–
–
corticosterone + NADPH + H+ <=> 5alpha-dihydrocorticosterone + NADP+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
1alpha,25-dihydroxyvitamin_D3 + NADPH + H+ + O2 <=> 1alpha,24,25-trihydroxyvitamin_D3 + NADP+ + H2O 1.14.15.16 vitamin D3 24-hydroxylase
–
(S)-1-phenyl-2-propanol + NADP+ <=> phenylacetone + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
benzylacetone + NADPH + H+ <=> (S)-4-phenylbutan-2-ol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
–
(+)-borneol + NADP+ <=> (+)-Camphor + NADPH + H+ 1.1.1.198 (+)-borneol dehydrogenase
–
L-arabinose + NADP+ <=> L-arabino-1,5-lactone + NADPH + H+ 1.1.1.120 galactose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
–
picolinaldehyde + NADPH + H+ <=> 2-hydroxymethylpyridine + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.65 pyridoxine 4-dehydrogenase
1.1.1.71 alcohol dehydrogenase [NAD(P)+]
–
–
–
–
L-cystine + NADPH + H+ <=> 2 L-cysteine + NADP+ 1.8.1.9 thioredoxin-disulfide reductase
–
(S)-N-methylcoclaurine + NADPH + H+ + O2 <=> (S)-3''-hydroxy-N-methylcoclaurine + NADP+ + H2O 1.14.13.71 N-methylcoclaurine 3'-monooxygenase
1.14.14.102 N-methylcoclaurine 3'-monooxygenase
–
–
Pentane-2,4-dione + NADPH + H+ <=> 4-hydroxypentan-2-one + NADP+ 1.1.1.149 20alpha-hydroxysteroid dehydrogenase
–
ethyl_2-oxobutanoate + NADPH + H+ <=> ethyl-2-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
methyl_4-chloro-3-oxobutanoate + NADPH + H+ <=> methyl_4-chloro-3-hydroxybutanoate + NADP+ 1.1.1.184 carbonyl reductase (NADPH)
–
Camphorquinone + NADPH + H+ <=> 1,7,7-trimethylbicyclo[2.2.1]heptane-2,3-diol + NADP+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
D-galactose_6-phosphate + NADP+ <=> 6-phospho-D-galactono-1,5-lactone + NADPH + H+ 1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.1.1.48 D-galactose 1-dehydrogenase
1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+)
–
–
–
fenthion + NADPH + H+ + O2 <=> fenthion-oxon + sulfur + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
L-tyrosine + O2 + NADPH + H+ <=> N-hydroxy-L-tyrosine + NADP+ + H2O 1.14.14.36 tyrosine N-monooxygenase
–
4-N-trimethylaminobutyraldehyde + NADP+ + H2O <=> gamma-butyrobetaine + NADPH + H+ 1.2.1.47 4-trimethylammoniobutyraldehyde dehydrogenase
–
pterin + NADPH + H+ <=> Tetrahydropterin + NADP+ 1.5.1.34 6,7-dihydropteridine reductase
–
butyryl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ <=> palmitate + (n+1)_CoA + n CO2 + 2n NADP+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
octanoyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ <=> palmitate + (n+1)_CoA + n CO2 + 2n NADP+ 2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
–
–
2-ethylbenzoate + NADP+ <=> 2-carboxybenzaldehyde + NADPH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.co
–
–
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 6-hydroxymellein + CoA + CO2 + NADP+ + H2O 2.3.1
–
M
NADPH + L-xylo-3-hexulose + H+ <=> D-sorbitol + NADP+ 1.1.1
–
M
aflatoxin_B1 + O2 + NADPH + H+ <=> Aflatoxin_B1-exo-8,9-epoxide + H2O + NADP+ 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
aflatoxin_B1 + O2 + NADPH + H+ <=> Aflatoxin_Q1 + H2O + NADP+ 1.14.13
1.14.14.1 unspecific monooxygenase
–
–
K
aflatoxin_B1 + O2 + NADPH + H+ <=> Aflatoxin_M1 + H2O + NADP+ 1.14.14.1 unspecific monooxygenase
–
K
cyclophosphamide + NADPH + H+ + O2 <=> 4-Hydroxycyclophosphamide + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
5alpha-androstane-3,17-dione + NADP+ <=> 4-androstene-3,17-dione + NADPH + H+ 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
–
K
(E,Z)-indolyl-3-acetaldoxime + L-cysteine + NADPH + O2 + H+ <=> S-(Indolylmethylthiohydroximoyl)-L-cysteine + NADP+ + 2 H2O 1.14.14.43 (methylsulfanyl)alkanaldoxime N-monooxygenase
1.14.14.45 aromatic aldoxime N-monooxygenase
–
–
K
17beta-estradiol + H+ + O2 + NADPH <=> 2-hydroxyestradiol + NADP+ + H2O 1.14.14.1 unspecific monooxygenase
–
K
tetrahydrocortisol + NADP+ <=> 11beta,17alpha,21-trihydroxy-5beta-pregnane-3,20-dione + NADPH + H+ 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
K
Tetrahydrocorticosterone + NADP+ <=> 5beta-dihydrocorticosterone + NADPH + H+ 1.1.1.209 3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
–
–
K
retinoic_acid + NADPH + H+ + O2 <=> all-trans-4-Hydroxyretinoic_acid + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
carbamazepine + NADPH + H+ + O2 <=> carbamazepine-10,11-epoxide + NADP+ + H2O 1.14.13
1.14.14.1 unspecific monooxygenase
1.14.14.55 quinine 3-monooxygenase
–
–
–
K
benzo(a)pyrene-7,8-diol + NADPH + O2 + H+ <=> Benzo[a]pyrene-7,8-dihydrodiol-9,10-oxide + NADP+ + H2O 1.14.13
1.14.14
1.14.14.1 unspecific monooxygenase
–
–
–
K
(R)-2,3-dihydroxy-3-methylbutanoate + NADP+ <=> 3-hydroxy-3-methyl-2-oxobutanoic_acid + NADPH + H+ 1.1.1.86 ketol-acid reductoisomerase (NADP+)
–
K
NADPH + 2 Ferrocytochrome