|
|
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine <=> GM1 + H+ + UDP
|
2.4.1.122
N-acetylgalactosaminide beta-1,3-galactosyltransferase
2.4.1.62
ganglioside galactosyltransferase
|
–
–
|
MK
|
| |
BRENDA:
BS322863
KEGG:
R04631;
R05941
MetaCyc:
GANGLIOSIDE-GALACTOSYLTRANSFERASE-RXN
|
|
|
|
UDP-N-acetyl-D-galactosamine + ganglioside_GM3 <=> N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H+ + UDP
|
2.4.1.92
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
|
–
|
MK
|
| |
BRENDA:
BS323116
KEGG:
R04584;
R05939
MetaCyc:
2.4.1.92-RXN
|
|
|
|
CMP-N-acetylneuraminate + ganglioside_asialo-GM2 <=> N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + CMP + H+
|
2.4.99.9
lactosylceramide alpha-2,3-sialyltransferase
|
–
|
|
| |
BRENDA:
BS388359
MetaCyc:
RXN-18292
|
|
|
|
CMP-N-acetylneuraminate + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine <=> ganglioside_GD2 + CMP + H+
|
2.4.99.8
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase
|
–
|
|
| |
KEGG:
R04632;
R06009
MetaCyc:
RXN-18284
|
|
|
|
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H2O <=> GalNAc-beta-1,4-Gal-beta-1,4-Glc-beta-1,1-Cer + N-acetylneuraminate
|
3.2.1.18
exo-alpha-sialidase
|
–
|
|
| |
KEGG:
R04634;
R06012
SABIO-RK:
4296
|
|
|
|
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H2O <=> ganglioside_GM3 + N-acetyl-D-galactosamine
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
| |
KEGG:
R04586
|
|
|
|
UDP-N-acetyl-D-galactosamine + ganglioside_GM3 <=> UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine
|
2.4.1.165
N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase
|
–
|
|
| |
KEGG:
R04615
|
|
|
|
CMP-N-acetylneuraminate + GalNAc-beta-1,4-Gal-beta-1,4-Glc-beta-1,1-Cer <=> CMP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine
|
2.4.99.9
lactosylceramide alpha-2,3-sialyltransferase
|
–
|
|
| |
KEGG:
R04630
|
|
|
|
GM1 + H2O <=> N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + D-galactose
|
3.2.1.23
beta-galactosidase
|
–
|
|
| |
KEGG:
R04633
|
|
|
|
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H2O <=> ganglioside_GM3 + N-acetyl-D-galactosamine
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
K
|
| |
KEGG:
R06004
|
|
|
|
CMP-N-acetylneuraminate + GalNAc-beta-1,4-Gal-beta-1,4-Glc-beta-1,1-Cer <=> CMP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine
|
2.4.99.9
lactosylceramide alpha-2,3-sialyltransferase
|
–
|
|
| |
KEGG:
R06007
|
|
|
|
GM1 + H2O <=> N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + D-galactose
|
3.2.1.23
beta-galactosidase
|
–
|
K
|
| |
KEGG:
R06010
|
|
|
|
UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine <=> UDP + beta-D-galactosyl-1,3-ganglioside_GM2
|
2.4.1.179
lactosylceramide beta-1,3-galactosyltransferase
|
–
|
|
| |
BRENDA:
BS355281
|
|
|
|
UDP-N-acetyl-D-galactosamine + ganglioside_GM3 <=> UDP-N-acetyl-D-galactosamine + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine
|
2.4.1.92
(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase
|
–
|
|
| |
BRENDA:
BS443956
|
|
|
|
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H2O <=> ganglioside_GM3 + N-acetyl-beta-D-galactosamine
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
| |
BRENDA:
BS446264
|
|
|
|
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H2O <=> GM3_ganglioside + N-acetyl-beta-D-galactosamine
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
| |
BRENDA:
BS382008
|
|
|
|
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H2O <=> lyso-GM2-ganglioside + fatty_acid
|
3.5.1.69
glycosphingolipid deacylase
|
–
|
|
| |
BRENDA:
BR29514
|
|
|
|
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H2O <=> N-acetyl-D-galactosamine
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
| |
BRENDA:
BS259872
|
|
|
|
H2O + GM1 <=> N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + beta-D-galactose
|
3.2.1.23
beta-galactosidase
|
–
|
|
| |
SABIO-RK:
14199
|
|
