|
|
indole-3-acetic_acid + L-lysine + ATP <=> H+ + N6-[(indole-3-yl)acetyl]-L-Lys + phosphate + ADP
|
6.3.2.20
indoleacetate---lysine synthetase
|
–
|
|
|
BRENDA:
BR113
KEGG:
R03095
MetaCyc:
INDOLEACETATE--LYSINE-LIGASE-RXN
|
|
|
|
UDP-MurNAc-L-Ala-D-Glu + L-lysine + ATP <=> H+ + phosphate + UDP-MurNAc-Ala-D-Glu-Lys + ADP
|
6.3.2.7
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase
|
–
|
BMK
|
|
BRENDA:
BR123;
BS427396
KEGG:
R02786
MetaCyc:
6.3.2.7-RXN
|
|
|
|
L-lysine <=> D-Lysine
|
5.1.1.1
alanine racemase
5.1.1.10
amino-acid racemase
5.1.1.5
lysine racemase
5.1.1.9
arginine racemase
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR173
KEGG:
R00460
MetaCyc:
LYSINE-RACEMASE-RXN
|
|
|
|
N6-acyl-L-lysine + H2O <=> a_carboxylate + L-lysine
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
|
BRENDA:
BR19237
KEGG:
R00545
MetaCyc:
ACYL-LYSINE-DEACYLASE-RXN
|
|
|
|
L-lysine + O2 + NADPH <=> N6-hydroxy-L-lysine + NADP+ + H2O
|
1.14.13.59
L-lysine N6-monooxygenase (NADPH)
|
–
|
BMK
|
|
BRENDA:
BR22599
KEGG:
R00448
MetaCyc:
1.14.13.59-RXN
|
|
|
|
L-lysine <=> L-beta-Lysine
|
5.4.3.2
lysine 2,3-aminomutase
|
–
|
BMK
|
|
BRENDA:
BR26
KEGG:
R00461
MetaCyc:
LYSINE-23-AMINOMUTASE-RXN
|
|
|
|
L-alpha-amino-epsilon-caprolactam + H2O <=> L-lysine
|
3.5.2.11
L-lysine-lactamase
|
–
|
|
|
BRENDA:
BR26102
KEGG:
R00463
MetaCyc:
L-LYSINE-LACTAMASE-RXN
|
|
|
|
meso-2,6-diaminoheptanedioate + H+ <=> L-lysine + CO2
|
4.1.1.20
diaminopimelate decarboxylase
|
–
|
BMK
|
|
BRENDA:
BR281;
BS390203
KEGG:
R00451
MetaCyc:
DIAMINOPIMDECARB-RXN
|
|
|
|
L-lysine + NAD+ <=> DELTA1-piperideine-2-carboxylate + NH3 + NADH + H+
|
1.4.1.15
lysine dehydrogenase
|
–
|
|
|
BRENDA:
BR36863
KEGG:
R00445
MetaCyc:
LYSINE-DEHYDROGENASE-RXN
|
|
|
|
L-lysine + NAD+ + H2O <=> H+ + (S)-2-amino-6-oxohexanoate + NADH + NH3
|
1.4.1.18
lysine 6-dehydrogenase
|
–
|
MK
|
|
BRENDA:
BR36866;
BS258926
KEGG:
R00446
MetaCyc:
RXN-8808
|
|
|
|
L-lysine + H2O + O2 <=> 6-Amino-2-oxohexanoate + NH3 + H2O2
|
1.13.12.2
lysine 2-monooxygenase
1.4.3.14
L-lysine oxidase
1.4.3.2
L-amino-acid oxidase
1.4.3.25
L-arginine oxidase
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR36876
KEGG:
R00447
MetaCyc:
L-LYSINE-OXIDASE-RXN
SABIO-RK:
887
|
|
|
|
H2O + NADP+ + D-lysopine <=> H+ + NADPH + pyruvate + L-lysine
|
1.5.1.11
D-octopine dehydrogenase
1.5.1.16
D-lysopine dehydrogenase
|
–
–
|
K
|
|
BRENDA:
BR36892
KEGG:
R00452
MetaCyc:
D-LYSOPINE-DEHYDROGENASE-RXN
|
|
|
|
saccharopine + H2O + NADP+ <=> L-lysine + 2-oxoglutarate + NADPH + H+
|
1.5.1.8
saccharopine dehydrogenase (NADP+, L-lysine-forming)
|
–
|
BMK
|
|
BRENDA:
BR36904
KEGG:
R00716
MetaCyc:
1.5.1.8-RXN
SABIO-RK:
1088
|
|
|
|
O2 + H2O + N6-methyl-L-lysine <=> H2O2 + formaldehyde + L-lysine
|
1.5.3.4
N6-methyl-lysine oxidase
|
–
|
|
|
BRENDA:
BR36908
KEGG:
R00612
MetaCyc:
N6-METHYL-LYSINE-OXIDASE-RXN
|
|
|
|
saccharopine + H2O + NAD+ <=> 2-oxoglutarate + L-lysine + NADH + H+
|
1.5.1.7
saccharopine dehydrogenase (NAD+, L-lysine-forming)
1.5.1.8
saccharopine dehydrogenase (NADP+, L-lysine-forming)
|
–
–
|
BMK
|
|
BRENDA:
BR37179
KEGG:
R00715
MetaCyc:
1.5.1.7-RXN
SABIO-RK:
1087
|
|
|
|
L-lysine + O2 <=> 5-Aminopentanamide + CO2 + H2O
|
1.13.12.2
lysine 2-monooxygenase
|
–
|
BMK
|
|
BRENDA:
BR40522
KEGG:
R00449
MetaCyc:
LYSINE-2-MONOOXYGENASE-RXN
|
|
|
|
L-lysine + Carbamoyl_phosphate <=> H+ + phosphate + L-Homocitrulline
|
2.1.3.3
ornithine carbamoyltransferase
2.1.3.8
lysine carbamoyltransferase
|
–
–
|
|
|
BRENDA:
BR43954
KEGG:
R01396
MetaCyc:
LYSINE-CARBAMOYLTRANSFERASE-RXN
SABIO-RK:
1590
|
|
|
|
L-lysine + acetyl_phosphate <=> H+ + phosphate + N6-acetyl-L-lysine
|
2.3.1.32
lysine N-acetyltransferase
|
–
|
K
|
|
BRENDA:
BR44032
KEGG:
R01620
MetaCyc:
LYSINE-N-ACETYLTRANSFERASE-RXN
|
|
|
|
2-oxoglutarate + L-lysine <=> L-glutamate + (S)-2-amino-6-oxohexanoate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.36
L-lysine 6-transaminase
|
–
–
|
BM
|
|
BRENDA:
BR47436;
BS354059
KEGG:
R00457
MetaCyc:
L-LYSINE-AMINOTRANSFERASE-RXN
SABIO-RK:
894
|
|
|
|
pyruvate + L-lysine <=> L-alanine + (S)-2-amino-6-oxohexanoate
|
2.6.1.36
L-lysine 6-transaminase
2.6.1.71
lysine---pyruvate 6-transaminase
|
–
–
|
M
|
|
BRENDA:
BR47707;
BS354071
KEGG:
R00453
MetaCyc:
LYSINE--PYRUVATE-6-AMINOTRANSFERASE-RXN
|
|
|
|
L-lysine + O2 + H2O <=> (S)-2-amino-6-oxohexanoate + H2O2 + NH3
|
1.4.3.20
L-lysine 6-oxidase
|
–
|
|
|
BRENDA:
BR48764;
BS386539
KEGG:
R07598
MetaCyc:
1.4.3.20-RXN
|
|
|
|
L-lysine <=> L-pipecolic_acid + NH3
|
4.3.1.28
L-lysine cyclodeaminase
|
–
|
|
|
BRENDA:
BR50338
KEGG:
R10277
MetaCyc:
RXN-13654
|
|
|
|
L-lysine <=> (3R)-3-methyl-D-ornithine
|
5.4.99.58
methylornithine synthase
|
–
|
MK
|
|
BRENDA:
BR50344
KEGG:
R10010
MetaCyc:
RXN-13074
|
|
|
|
L-gamma-glutamyl-L-epsilon-lysine <=> L-lysine + 5-oxoproline
|
4.3.2.8
gamma-glutamylamine cyclotransferase
4.3.2.9
gamma-glutamylcyclotransferase
|
–
–
|
|
|
BRENDA:
BR52223
KEGG:
R11862
MetaCyc:
RXN-19023
|
|
|
|
L-arginine + L-lysine <=> L-ornithine + L-homoarginine
|
2.1.4.1
glycine amidinotransferase
2.1.4.3
L-arginine:L-lysine amidinotransferase
|
–
–
|
|
|
BRENDA:
BR52910;
BS320133
KEGG:
R12506
MetaCyc:
RXN-13073
|
|
|
|
L-lysine + H+ <=> cadaverine + CO2
|
4.1.1.17
ornithine decarboxylase
4.1.1.18
lysine decarboxylase
4.1.1.19
arginine decarboxylase
4.1.1.50
adenosylmethionine decarboxylase
4.1.1.86
diaminobutyrate decarboxylase
4.1.1.B12
|
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR6435
KEGG:
R00462
MetaCyc:
LYSDECARBOX-RXN
SABIO-RK:
899
|
|
|
|
epsilon-N-biotinyl-L-lysine + H2O <=> biotin + L-lysine
|
3.5.1.12
biotinidase
|
–
|
K
|
|
BRENDA:
BS116041
KEGG:
R01077
MetaCyc:
RXN-16474
|
|
|
|
ATP + L-lysine + H2O <=> ADP + phosphate + L-lysine + H+
|
7.4.2.1
ABC-type polar-amino-acid transporter
7.4.2.2
ABC-type nonpolar-amino-acid transporter
|
–
–
|
|
|
BRENDA:
BS165508
MetaCyc:
ABC-3-RXN
|
|
|
|
L-lysine + NAD+ <=> H+ + DELTA1-piperidine_6-carboxylate + NADH + NH3
|
1.4.1.15
lysine dehydrogenase
1.4.1.18
lysine 6-dehydrogenase
|
–
–
|
|
|
BRENDA:
BS258915
KEGG:
R10054
MetaCyc:
LYSINE-6-DEHYDROGENASE-RXN
|
|
|
|
L-lysine + 2-oxoglutarate <=> 6-Amino-2-oxohexanoate + L-glutamate
|
2.6.1
2.6.1.42
branched-chain-amino-acid transaminase
|
–
–
|
M
|
|
BRENDA:
BS356599
MetaCyc:
RXN66-565
|
|
|
|
L-lysine <=> 3,6-Diaminohexanoate
|
5.4.3
5.4.3.2
lysine 2,3-aminomutase
|
–
–
|
|
|
BRENDA:
BS392392
MetaCyc:
RXN0-5192
|
|
|
|
L-lysine + acetyl-CoA <=> H+ + N6-acetyl-L-lysine + CoA
|
2.3.1
2.3.1.32
lysine N-acetyltransferase
|
–
–
|
BMK
|
|
BRENDA:
BS407086
KEGG:
R00454
MetaCyc:
LYSACET-RXN
|
|
|
|
[tRNAIle2]-cytidine34 + L-lysine + ATP <=> [tRNAIle2]-2-L-lysylcytidine34 + AMP + diphosphate + H2O
|
6.3.4.19
tRNAIle-lysidine synthase
|
–
|
|
|
BRENDA:
BR49270
KEGG:
R09597
|
|
|
|
L-lysine + (8S)-8-amino-7-oxononanoate <=> (S)-2-amino-6-oxohexanoate + (7R,8S)-diaminononanoate
|
2.6.1.105
lysine---8-amino-7-oxononanoate transaminase
|
–
|
MK
|
|
BRENDA:
BR50965
KEGG:
R10699
MetaCyc:
RXN-14930
|
|
|
|
ATP + L-lysine + tRNAMet <=> AMP + diphosphate + L-lysyl-tRNALys
|
6.1.1.6
lysine---tRNA ligase
|
–
|
BK
|
|
BRENDA:
BR57
KEGG:
R03658
SABIO-RK:
414
|
|
|
|
N6-acetyl-L-lysine + H2O <=> L-lysine + acetate
|
3.5.1.17
acyl-lysine deacylase
|
–
|
K
|
|
BRENDA:
BS116187
KEGG:
R00458
|
|
|
|
L-Ala-gamma-D-Glu-L-Lys + H2O <=> L-Ala-D-Glu + L-lysine
|
3.4.14.13
gamma-D-glutamyl-L-lysine dipeptidyl-peptidase
|
–
|
|
|
BRENDA:
BS430288
KEGG:
R11190
|
|
|
|
N-alpha-acetyl-L-lysine + H2O <=> L-lysine + acetate
|
3.5.1.114
N-acyl-aromatic-L-amino acid amidohydrolase
3.5.1.14
N-acyl-aliphatic-L-amino acid amidohydrolase
3.5.1.15
aspartoacylase
3.5.1.16
acetylornithine deacetylase
3.5.1.17
acyl-lysine deacylase
|
–
–
–
–
–
|
|
|
BRENDA:
BS116178
SABIO-RK:
6420;
8122
|
|
|
|
L-Lys-4-nitroanilide + H2O <=> L-lysine + 4-nitroaniline
|
3.3.2.6
leukotriene-A4 hydrolase
3.4.11.1
leucyl aminopeptidase
3.4.11.10
bacterial leucyl aminopeptidase
3.4.11.15
aminopeptidase Y
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.20
aminopeptidase Ey
3.4.11.22
aminopeptidase I
3.4.11.24
aminopeptidase S
3.4.11.3
cystinyl aminopeptidase
3.4.11.4
tripeptide aminopeptidase
3.4.11.5
prolyl aminopeptidase
3.4.11.6
aminopeptidase B
3.4.11.B3
3.4.11.B9
3.4.13.20
beta-Ala-His dipeptidase
3.4.21.50
lysyl endopeptidase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS14572
SABIO-RK:
12933
|
|
|
|
L-lysine-4-methylcoumaryl-7-amide + H2O <=> L-lysine + 7-amino-4-methylcoumarin
|
3.3.2.6
leukotriene-A4 hydrolase
3.4.11.1
leucyl aminopeptidase
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.15
aminopeptidase Y
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.3
cystinyl aminopeptidase
3.4.11.6
aminopeptidase B
3.4.13.18
cytosol nonspecific dipeptidase
3.4.22.16
cathepsin H
|
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS355557
SABIO-RK:
12398
|
|
|
|
dynorphin_A(1-13) + H2O <=> Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu + L-lysine
|
3.4.17.12
carboxypeptidase M
3.4.17.23
angiotensin-converting enzyme 2
|
–
–
|
|
|
BRENDA:
BS361761
SABIO-RK:
13317
|
|
|
|
Lys-p-nitroanilide + H2O <=> L-lysine + 4-nitroaniline
|
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.21.50
lysyl endopeptidase
3.4.22.40
bleomycin hydrolase
|
–
–
–
–
|
|
|
BRENDA:
BS36248
SABIO-RK:
14445
|
|
|
|
Lys-Gly-Gly + H2O <=> L-lysine + Gly-Gly
|
3.4.11.15
aminopeptidase Y
3.4.11.4
tripeptide aminopeptidase
|
–
–
|
|
|
BRENDA:
BS364822
SABIO-RK:
12934
|
|
|
|
L-homoarginine + H2O <=> L-lysine + Urea
|
3.5.3.1
arginase
|
–
|
|
|
BRENDA:
BS384992
SABIO-RK:
7980
|
|
|
|
Lys-Pro + H2O <=> L-lysine + L-proline
|
3.4.13.9
Xaa-Pro dipeptidase
|
–
|
|
|
BRENDA:
BS394405
SABIO-RK:
11279
|
|
|
|
Lys-Phe + H2O <=> L-lysine + L-phenylalanine
|
3.4.11.15
aminopeptidase Y
3.4.11.2
membrane alanyl aminopeptidase
|
–
–
|
|
|
BRENDA:
BS405614
SABIO-RK:
9768
|
|
|
|
(Met)enkephalin-Lys + H2O <=> Met-enkephalin + L-lysine
|
3.4.17.10
carboxypeptidase E
3.4.17.12
carboxypeptidase M
|
–
–
|
|
|
BRENDA:
BS64989
SABIO-RK:
12333
|
|
|
|
L-lysine <=> L-pipecolic_acid
|
not assigned
|
–
|
|
|
KEGG:
R00459
|
|
|
|
ATP + L-lysine + beta-Alanine <=> ADP + phosphate + beta-Ala-Lys
|
6.3.2.11
carnosine synthase
|
–
|
K
|
|
KEGG:
R00910
|
|
|
|
beta-Ala-Lys + H2O <=> beta-Alanine + L-lysine
|
3.4.13.4
Xaa-Arg dipeptidase
|
–
|
K
|
|
KEGG:
R00911
|
|
|
|
ATP + L-lysine + tRNA(Pyl) <=> AMP + diphosphate + L-Lysyl-tRNA(Pyl)
|
not assigned
|
–
|
|
|
KEGG:
R07646
|
|
|
|
N6-(6-phospho-D-fructosyl)-L-lysine + H2O <=> L-lysine + D-glucose_6-phosphate
|
3.5
|
–
|
|
|
KEGG:
R08125
|
|
|
|
LysW-gamma-L-lysine + H2O <=> L-lysine + [LysW]-C-terminal-L-glutamate
|
3.5.1.130
[amino group carrier protein]-lysine hydrolase
|
–
|
K
|
|
KEGG:
R09779
|
|
|
|
L-lysine + (3R)-3-methyl-D-ornithine + ATP <=> (2R,3R)-3-Methylornithinyl-N6-lysine + products_of_ATP_breakdown
|
6.3.2
|
–
|
K
|
|
KEGG:
R10011
|
|
|
|
L-lysine + 2-oxoglutarate + O2 + Cl- + H+ <=> 4-Chloro-L-lysine + succinate + CO2 + H2O
|
1.14.20
|
–
|
K
|
|
KEGG:
R12407
|
|
|
|
L-lysine + tRNAMet + ATP <=> L-lysyl-[tRNALys] + diphosphate + AMP
|
6.1.1.6
lysine---tRNA ligase
|
–
|
M
|
|
MetaCyc:
LYSINE--TRNA-LIGASE-RXN
|
|
|
|
L-glutamate + L-tyrosine + L-2,4-diaminobutanoate + L-serine + L-arginine + N5-formyl-N5-hydroxy-L-ornithine + L-lysine + L-threonine + myristoyl-CoA + ATP <=> myristoylated_ferribactin + CoA + H2O + AMP + diphosphate + H+
|
6.3.2
|
–
|
M
|
|
MetaCyc:
RXN-11126
|
|
|
|
(3R)-3-methyl-D-ornithine + L-lysine + ATP <=> H+ + (2R,3R)-3-Methylornithinyl-N6-lysine + ADP + phosphate
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13080
|
|
|
|
D-ornithine + L-lysine + ATP <=> epsilon-(D-ornithyl)-L-lysine + ADP + phosphate + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-13083
|
|
|
|
L-lysine <=> DELTA1-piperidine_6-carboxylate
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-16669
|
|
|
|
peptide_with_an_N-terminal_L-lysine + H2O <=> L-lysine + peptide
|
3.4.11.15
aminopeptidase Y
3.4.11.6
aminopeptidase B
|
–
–
|
|
|
MetaCyc:
RXN-18719
|
|
|
|
lisdexamfetamine + H2O <=> D-amphetamine + L-lysine
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-19388
|
|
|
|
cytidine34_in_tRNAIle2 + L-lysine + ATP <=> [tRNA(Ile2)]-lysidine34 + AMP + diphosphate + H+
|
6.3.4.19
tRNAIle-lysidine synthase
|
–
|
|
|
MetaCyc:
RXN-1961
|
|
|
|
[peptide]_with_a_C-terminal_L-lysine + H2O <=> peptide + L-lysine
|
3.4.16.6
carboxypeptidase D
3.4.17.10
carboxypeptidase E
3.4.17.12
carboxypeptidase M
3.4.17.2
carboxypeptidase B
3.4.17.20
carboxypeptidase U
3.4.17.22
metallocarboxypeptidase D
|
–
–
–
–
–
–
|
|
|
MetaCyc:
RXN-19940
|
|
|
|
dipeptide_with_a_C-terminal_L-lysine + H2O <=> proteinogenic_amino_acid + L-lysine
|
3.4.13.4
Xaa-Arg dipeptidase
|
–
|
|
|
MetaCyc:
RXN-19942
|
|
|
|
aldehydo-D-glucose + L-lysine <=> fructoselysine + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20898
|
|
|
|
keto-D-fructose + L-lysine <=> N6-(D-glucosyl)-L-lysine + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20900
|
|
|
|
[amino-group_carrier_protein]-C-terminal-[gamma-(L-lysyl)-L-glutamate] + H2O <=> L-lysine + [amino_group_carrier_protein]-C-terminal-L-glutamate
|
3.5.1.130
[amino group carrier protein]-lysine hydrolase
|
–
|
M
|
|
MetaCyc:
RXN-5185
|
|
|
|
N6-(6-phospho-D-fructosyl)-L-lysine + H2O <=> beta-D-glucose_6-phosphate + L-lysine
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN0-963
|
|
|
|
H2O + N6-(6-phospho-D-glucosyl)-L-lysine <=> L-lysine + D-fructose_6-phosphate
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN1QP9-73
|
|
|
|
L-lysine + H+ <=> L-lysine + H+
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-401
|
|
|
|
H+ + L-lysine <=> H+ + L-lysine
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-58
|
|
|
|
cadaverine + L-lysine <=> cadaverine + L-lysine
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-68
|
|
|
|
L-lysine <=> L-lysine
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN0-569
|
|
|
|
L-lysine + Iodine + O2 <=> N6-hydroxy-L-lysine + IO3- + H2O
|
1.14.13.59
L-lysine N6-monooxygenase (NADPH)
|
–
|
|
|
BRENDA:
BS377055
|
|
|
|
Lys-Gly-Gly-Lys + H2O <=> L-lysine + Gly-Gly-Lys
|
3.4.11.15
aminopeptidase Y
|
–
|
|
|
BRENDA:
BS423805
|
|
|
|
D-glyceraldehyde_3-phosphate + L-lysine <=> N2-(2-carboxyethyl)-L-lysine + phosphate
|
2.5.1.66
N2-(2-carboxyethyl)arginine synthase
|
–
|
|
|
BRENDA:
BS407193
|
|
|
|
L-lysine + 4,5-Dioxopentanoate <=> 5-aminolevulinate + 6-Amino-2-oxohexanoate
|
2.6.1.43
aminolevulinate transaminase
|
–
|
|
|
BRENDA:
BS356621
|
|
|
|
Met5-Lys6-enkephalin + H2O <=> Met-enkephalin + L-lysine
|
3.4.17.20
carboxypeptidase U
|
–
|
|
|
BRENDA:
BS15068
|
|
|
|
aminoacyl-L-lysine + H2O <=> L-lysine + acylamine
|
3.4.13.4
Xaa-Arg dipeptidase
|
–
|
|
|
BRENDA:
BS36418
|
|
|
|
L-Lys-7-amido-4-carbamoylmethylcoumarin + H2O <=> L-lysine + 7-amino-4-carbamoylmethylcoumarin
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS432038
|
|
|
|
Benzoyl-Ala-Lys + H2O <=> Benzoyl-Ala + L-lysine
|
3.4.17.12
carboxypeptidase M
|
–
|
|
|
BRENDA:
BS361759
|
|
|
|
L-lysine + 2-oxoadipate <=> 2-aminoadipate_6-semialdehyde + adipate
|
2.6.1.36
L-lysine 6-transaminase
|
–
|
|
|
BRENDA:
BS354072
|
|
|
|
2-chloroadenosine_5''-triphosphate + L-lysine + tRNAMet <=> 2-chloroadenosine_5''-monophosphate + Lys-tRNALys + diphosphate
|
6.1.1.6
lysine---tRNA ligase
|
–
|
|
|
BRENDA:
BS133
|
|
|
|
dATP + L-lysine + tRNAMet <=> dAMP + L-lysyl-tRNALys + diphosphate
|
6.1.1.6
lysine---tRNA ligase
|
–
|
|
|
BRENDA:
BS132
|
|
|
|
formycin_5''-triphosphate + L-lysine + tRNAMet <=> formycin_5''-monophosphate + diphosphate + L-lysyl-tRNALys
|
6.1.1.6
lysine---tRNA ligase
|
–
|
|
|
BRENDA:
BS134
|
|
|
|
[tRNAIle2]-cytidine34 + L-lysine + 8-azidoadenosine_5''-triphosphate <=> [tRNAIle2]-2-L-lysylcytidine34 + 8-azidoadenosine_5''-phosphate + diphosphate
|
6.3.4.19
tRNAIle-lysidine synthase
|
–
|
|
|
BRENDA:
BS410662
|
|
|
|
[tRNAIle2]-cytidine34 + L-lysine + N6-methyladenosine-5''-triphosphate <=> [tRNAIle2]-2-L-lysylcytidine34 + N6-methyladenosine-5''-phosphate + diphosphate
|
6.3.4.19
tRNAIle-lysidine synthase
|
–
|
|
|
BRENDA:
BS410664
|
|
|
|
[tRNAIle2]-cytidine34 + L-lysine + 7-deazaadenosine_5''-triphosphate <=> [tRNAIle2]-2-L-lysylcytidine34 + 7-deazaadenosine_5''-phosphate + diphosphate
|
6.3.4.19
tRNAIle-lysidine synthase
|
–
|
|
|
BRENDA:
BS410661
|
|
|
|
L-lysine + 2-oxobutyrate <=> 2-aminoadipate_6-semialdehyde + 2-aminobutanoate
|
2.6.1.36
L-lysine 6-transaminase
|
–
|
|
|
BRENDA:
BS354069
|
|
|
|
Pro-Phe-Gly-Lys + H2O <=> Pro-Phe-Gly + L-lysine
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36755
|
|
|
|
benzyloxycarbonyl-Val-Gly-Lys-Lys + H2O <=> L-lysine + benzyloxycarbonyl-Val-Gly-Lys
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36752
|
|
|
|
Arg-Lys + H2O <=> L-arginine + L-lysine
|
3.4.11.6
aminopeptidase B
|
–
|
|
|
BRENDA:
BS364828
|
|
|
|
L-Lys-Pro-7-amido-4-carbamoylmethylcoumarin + H2O <=> L-lysine + Pro-7-amido-4-carbamoylmethylcoumarin
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS450174
|
|
|
|
L-lysine + 3-acetylpyridine_adenine_dinucleotide + H2O <=> 2-aminoadipate_6-semialdehyde + NH3 + reduced_acetylpyridine_adenine_dinucleotide
|
1.4.1.18
lysine 6-dehydrogenase
|
–
|
|
|
BRENDA:
BS409696
|
|
|
|
L-lysine + nicotinamide_guanine_dinucleotide + H2O <=> 2-aminoadipate_6-semialdehyde + NH3 + nicotinamide_guanine_dinucleotide
|
1.4.1.18
lysine 6-dehydrogenase
|
–
|
|
|
BRENDA:
BS409701
|
|
|
|
L-lysine + O2 + H2O2 <=> 2-aminoadipate_6-semialdehyde + NH3 + H2O2
|
1.4.3.20
L-lysine 6-oxidase
|
–
|
|
|
BRENDA:
BS397624
|
|
|
|
L-lysine + H2O + O2 <=> 2-aminohexanoate + NH3 + H2O2
|
1.4.3.22
diamine oxidase
|
–
|
|
|
BRENDA:
BS259120
|
|
|
|
L-lysine + deamido-NAD+ + H2O <=> 2-aminoadipate_6-semialdehyde + NH3 + deamino-NADH
|
1.4.1.18
lysine 6-dehydrogenase
|
–
|
|
|
BRENDA:
BS409697
|
|
|
|
L-lysine + phenazine_methosulfate <=> 6-Amino-2-oxohexanoate + NH3 + reduced_phenazine_methosulfate
|
1.13.12.2
lysine 2-monooxygenase
|
–
|
|
|
BRENDA:
BS289287
|
|
|
|
DL-2,6-Diaminoheptanedioate <=> L-lysine + CO2
|
4.1.1.20
diaminopimelate decarboxylase
|
–
|
|
|
BRENDA:
BS416933
|
|
|
|
polylysine + H2O <=> L-lysine
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36761
|
|
|
|
N6,N6-dimethyl-L-lysine + O2 + H2O <=> L-lysine + formaldehyde + H2O2
|
1.5.3.4
N6-methyl-lysine oxidase
|
–
|
|
|
BRENDA:
BS259350
|
|
|
|
epsilon-pyridoxyllysine_5''-phosphate + H2O + O2 <=> pyridoxal_5''-phosphate + L-lysine + H2O2
|
1.4.3.5
pyridoxal 5'-phosphate synthase
|
–
|
|
|
BRENDA:
BS259096
|
|
|
|
alpha-N-(5''-phospho-4''-pyridoxyl)-L-lysine + H2O + O2 <=> pyridoxal_5''-phosphate + L-lysine + H2O2
|
1.4.3.5
pyridoxal 5'-phosphate synthase
|
–
|
|
|
BRENDA:
BS451616
|
|
|
|
N6-ethyl-L-lysine + H2O + O2 <=> L-lysine + acetaldehyde + H2O2
|
1.5.3.4
N6-methyl-lysine oxidase
|
–
|
|
|
BRENDA:
BS259352
|
|
|
|
Gly-His-Lys + H2O <=> Gly-His + L-lysine
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36757
|
|
|
|
Lys-Lys-Lys + H2O <=> L-lysine + Lys-Lys
|
3.4.11.15
aminopeptidase Y
|
–
|
|
|
BRENDA:
BS361395
|
|
|
|
Lys6-Leu5-enkephalin + H2O <=> Leu-enkephalin + L-lysine
|
3.4.17.20
carboxypeptidase U
|
–
|
|
|
BRENDA:
BS15066
|
|
|
|
N-Carbobenzoxy-Ala-Ala-Lys + H2O <=> Benzyloxycarbonyl-Ala-Ala + L-lysine
|
3.4.17.18
carboxypeptidase T
|
–
|
|
|
BRENDA:
BS361781
|
|
|
|
Nepsilon-(5-L-glutamyl)-L-lysine <=> 5-oxoproline + L-lysine
|
4.3.2.9
gamma-glutamylcyclotransferase
|
–
|
|
|
BRENDA:
BS321730
|
|
|
|
Fibrin + H2O <=> Fibrin + L-lysine
|
3.4.17.20
carboxypeptidase U
|
–
|
|
|
BRENDA:
BS383158
|
|
|
|
Tyr-Gly-Gly-Phe-Leu-Lys + H2O <=> Leu-enkephalin + L-lysine
|
3.4.17.22
metallocarboxypeptidase D
|
–
|
|
|
BRENDA:
BS361732
|
|
|
|
Arg-Lys-somatostatin-14 + H2O <=> L-arginine + L-lysine + Somatostatin-14
|
3.4.11.6
aminopeptidase B
|
–
|
|
|
BRENDA:
BS381438
|
|
|
|
2 L-lysine + L-homocystine <=> GSSG + 2 L-homocysteine
|
1.8.4.1
glutathione---homocystine transhydrogenase
|
–
|
|
|
BRENDA:
BS440544
|
|
|
|
kallidin + H2O <=> L-lysine + bradykinin
|
3.4.11.6
aminopeptidase B
3.4.11.7
glutamyl aminopeptidase
|
–
–
|
|
|
BRENDA:
BS382085
|
|
|
|
L-lysine + 2-Oxohexanoate <=> 2-aminoadipate_6-semialdehyde + 2-aminohexanoate
|
2.6.1.36
L-lysine 6-transaminase
|
–
|
|
|
BRENDA:
BS354066
|
|
|
|
L-lysine + 2-Oxopentanoate <=> 2-aminoadipate_6-semialdehyde + 2-aminopentanoate
|
2.6.1.36
L-lysine 6-transaminase
|
–
|
|
|
BRENDA:
BS354067
|
|
|
|
Benzyloxycarbonyl-Ala-Lys + H2O <=> Benzyloxycarbonyl-Ala + L-lysine
|
3.4.17.B5
|
–
|
|
|
BRENDA:
BS421067
|
|
|
|
Lys-Lys-Lys-Lys + H2O <=> L-lysine + Lys-Lys-Lys
|
3.4.11.15
aminopeptidase Y
|
–
|
|
|
BRENDA:
BS423808
|
|
|
|
N2-(4-aminobutyryl)-L-lysine + H2O <=> 4-aminobutanoate + L-lysine
|
3.4.13.4
Xaa-Arg dipeptidase
|
–
|
|
|
BRENDA:
BS382396
|
|
|
|
Pro-Lys + H2O <=> L-proline + L-lysine
|
3.4.11.5
prolyl aminopeptidase
3.4.13.18
cytosol nonspecific dipeptidase
|
–
–
|
|
|
BRENDA:
BS36303
|
|
|
|
L-pyroglutamyl-Lys + H2O <=> 5-oxoproline + L-lysine
|
3.4.19.3
pyroglutamyl-peptidase I
|
–
|
|
|
BRENDA:
BS74131
|
|
|
|
Lys-Arg + H2O <=> L-lysine + L-arginine
|
3.4.11.2
membrane alanyl aminopeptidase
|
–
|
|
|
BRENDA:
BS394379
|
|
|
|
Pro-Phe-Lys + H2O <=> Pro-Phe + L-lysine
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36756
|
|
|
|
1''-N-methoxycarbonyl-biocytin + H2O <=> 1-N-methoxycarbonyl-biotin + L-lysine
|
3.5.1.12
biotinidase
|
–
|
|
|
BRENDA:
BS116046
|
|
|
|
N6-benzoyl-L-lysine + H2O <=> L-lysine + benzoate
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
|
BRENDA:
BS116185
|
|
|
|
N6-benzoyl-L-lysine + H2O <=> L-lysine + phenylacetate
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
|
BRENDA:
BS116200
|
|
|
|
N6-chloroacetyl-L-lysine + H2O <=> L-lysine + Chloroacetate
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
|
BRENDA:
BS116189
|
|
|
|
Lys-Pro-p-nitroanilide + H2O <=> L-lysine + Pro-p-nitroanilide
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS36355
|
|
|
|
S-adenosyl-L-methionine + L-lysine <=> S-adenosyl-L-homocysteine + methyl-L-Lys
|
2.1.1.127
[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase
|
–
|
|
|
BRENDA:
BS377712
|
|
|
|
S-adenosyl-L-methionine + L-lysine <=> S-adenosyl-L-homocysteine + N6-methyl-L-lysine
|
2.1.1.301
cypemycin N-terminal methyltransferase
|
–
|
|
|
BRENDA:
BS430688
|
|
|
|
L-Lys-2-naphthylamide + H2O <=> L-lysine + 2-Naphthylamine
|
3.4.11.14
cytosol alanyl aminopeptidase
3.4.11.2
membrane alanyl aminopeptidase
3.4.11.21
aspartyl aminopeptidase
3.4.11.22
aminopeptidase I
3.4.11.3
cystinyl aminopeptidase
3.4.11.6
aminopeptidase B
3.4.11.7
glutamyl aminopeptidase
3.4.21.9
enteropeptidase
3.4.22.16
cathepsin H
3.5.1.13
aryl-acylamidase
|
–
–
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS140295
|
|
|
|
DL-alpha-amino-beta-caprolactam + H2O <=> D-alpha-amino-beta-caprolactam + L-lysine
|
3.5.2.11
L-lysine-lactamase
|
–
|
|
|
BRENDA:
BS376725
|
|
|
|
L-lysine + 2-oxoglutarate <=> 2-aminoadipate_6-semialdehyde + DELTA1-piperidine_6-carboxylate + L-glutamate
|
2.6.1.36
L-lysine 6-transaminase
|
–
|
|
|
BRENDA:
BS397618
|
|
|
|
L-lysine + 2-oxoglutarate <=> L-glutamate + 2-amino-7-oxooctanoic_acid
|
2.6.1.13
ornithine aminotransferase
|
–
|
|
|
BRENDA:
BS354106
|
|
|
|
L-lysine + H2O + NAD+ <=> 6-Amino-2-oxohexanoate + NH3 + NADH + H+
|
1.4.1.9
leucine dehydrogenase
|
–
|
|
|
BRENDA:
BS441522
|
|
|
|
L-lysine + NADH + H+ + O2 <=> N6-hydroxy-L-lysine + NAD+ + H2O
|
1.14.13.59
L-lysine N6-monooxygenase (NADPH)
|
–
|
|
|
BRENDA:
BS428732
|
|
|
|
L-lysine + pyruvate + NADH <=> D-lysopine + NAD+ + H2O
|
1.5.1.11
D-octopine dehydrogenase
|
–
|
|
|
BRENDA:
BS6352
|
|
|
|
Lys-Ala-7-amido-4-methylcoumarin + H2O <=> L-lysine + L-alanine-4-methylcoumaryl-7-amide
|
3.4.11.15
aminopeptidase Y
|
–
|
|
|
BRENDA:
BS361381
|
|
|
|
Hippuryl-L-Lys + H2O <=> hippuric_acid + L-lysine
|
3.4.16.5
carboxypeptidase C
3.4.17.12
carboxypeptidase M
3.4.17.2
carboxypeptidase B
3.4.17.20
carboxypeptidase U
3.4.17.3
lysine carboxypeptidase
|
–
–
–
–
–
|
|
|
BRENDA:
BS15060
|
|
|
|
Lys-plasminogen + H2O <=> L-lysine + plasmin
|
3.4.17.20
carboxypeptidase U
|
–
|
|
|
BRENDA:
BS383235
|
|
|
|
anisylazoformyl-Lys + H2O <=> anisylazoformic_acid + L-lysine
|
3.4.17.20
carboxypeptidase U
|
–
|
|
|
BRENDA:
BS365030
|
|
|
|
Fibrin,_partially_degraded + H2O <=> Fibrin,_partially_degraded + L-lysine + L-arginine
|
3.4.17.20
carboxypeptidase U
|
–
|
|
|
BRENDA:
BS15058
|
|
|
|
Lys-Leu + H2O <=> L-lysine + L-leucine
|
3.4.11.15
aminopeptidase Y
|
–
|
|
|
BRENDA:
BS423806
|
|
|
|
Val-Lys + H2O <=> L-valine + L-lysine
|
3.4.13.23
cysteinylglycine-S-conjugate dipeptidase
|
–
|
|
|
BRENDA:
BS450195
|
|
|
|
pGlu-Leu-Thr-Phe-Ser-Pro-Asp-Trp-Gly-Lys + H2O <=> pGlu-Leu-Thr-Phe-Ser-Pro-Asp-Trp-Gly + L-lysine
|
3.4.17.22
metallocarboxypeptidase D
|
–
|
|
|
BRENDA:
BS412673
|
|
|
|
alpha-Factor-Lys-Arg + H2O <=> Mature_active_alpha-factor + L-lysine + L-arginine
|
3.4.16.6
carboxypeptidase D
|
–
|
|
|
BRENDA:
BS361722
|
|
|
|
L-lysine + NADP+ + H2O <=> (S)-2-amino-6-oxohexanoate + NADPH + H+ + NH3
|
1.4.1.18
lysine 6-dehydrogenase
|
–
|
|
|
BRENDA:
BS413437
|
|
|
|
L-lysine + NADP+ <=> 2-aminoadipate_6-semialdehyde + NADPH
|
1.4.1.18
lysine 6-dehydrogenase
|
–
|
|
|
BRENDA:
BS373601
|
|
|
|
L-lysine + pyruvate + NADPH <=> N7-(1-carboxyethyl)lysine + NADP+ + H2O
|
1.5.1.24
N5-(carboxyethyl)ornithine synthase
|
–
|
|
|
BRENDA:
BS259237
|
|
|
|
L-lysine + NADPH + H+ + O2 <=> N5-hydroxy-L-lysine + NADP+ + H2O
|
1.14.13.195
L-ornithine N5-monooxygenase (NADPH)
|
–
|
|
|
BRENDA:
BS441523
|
|
|
|
L-lysine + NADPH + H+ + O2 <=> L-lysine_N6-oxide + NADP+ + H2O
|
1.14.13.195
L-ornithine N5-monooxygenase (NADPH)
|
–
|
|
|
BRENDA:
BS407250
|
|
|
|
N2-Lys-ubiquitin + H2O <=> ubiquitin + L-lysine
|
3.4.19.12
ubiquitinyl hydrolase 1
|
–
|
|
|
BRENDA:
BS36809
|
|
|
|
N6-Lys-ubiquitin + H2O <=> ubiquitin + L-lysine
|
3.4.19.12
ubiquitinyl hydrolase 1
|
–
|
|
|
BRENDA:
BS36808
|
|
|
|
L-lysine <=> 2,5-Diaminohexanoate
|
5.4.3.3
lysine 5,6-aminomutase
|
–
|
|
|
BRENDA:
BS368772
|
|
|
|
Lys-tRNA + H2O <=> L-lysine + tRNA
|
3.1.1.29
aminoacyl-tRNA hydrolase
|
–
|
|
|
BRENDA:
BS362950
|
|
|
|
furylacryloyl-Ala-Lys + H2O <=> furylacryloyl-Ala + L-lysine
|
3.4.16.5
carboxypeptidase C
3.4.16.6
carboxypeptidase D
3.4.17.12
carboxypeptidase M
3.4.17.20
carboxypeptidase U
3.4.17.B1
|
–
–
–
–
–
|
|
|
BRENDA:
BS15061
|
|
|
|
5-L-glutamyl-L-lysine + acceptor <=> L-lysine + 5-L-Glutamyl-acceptor
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
|
|
BRENDA:
BS321685
|
|
|
|
2-N-(5-L-Glutamyl)L-lysine <=> 5-oxoproline + L-lysine
|
4.3.2.9
gamma-glutamylcyclotransferase
|
–
|
|
|
BRENDA:
BS321723
|
|
|
|
Benzyloxycarbonyl-Gly-Lys + H2O <=> Benzyloxycarbonyl-Gly + L-lysine
|
3.4.16.6
carboxypeptidase D
|
–
|
|
|
BRENDA:
BS431665
|
|
|
|
SDF-1alpha + H2O <=> des-lys_SDF-1alpha + L-lysine
|
3.4.17.12
carboxypeptidase M
|
–
|
|
|
BRENDA:
BS394498
|
|
|
|
L-Lysine_ethyl_ester + H2O <=> L-lysine + ethanol
|
3.1.1.3
triacylglycerol lipase
|
–
|
|
|
BRENDA:
BS417163
|
|
|
|
N6-Formyl-L-lysine + H2O <=> L-lysine + formate
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
|
BRENDA:
BS116214
|
|
|
|
L-Lys-peptide + H2O <=> L-lysine + peptide
|
3.4.11.6
aminopeptidase B
|
–
|
|
|
BRENDA:
BS36316
|
|
|
|
L-Lys-tRNALys + H2O <=> L-lysine + tRNAMet
|
3.1.1.29
aminoacyl-tRNA hydrolase
|
–
|
|
|
BRENDA:
BS417162
|
|
|
|
D-Tyr-Ala-His-Lys-Lys + H2O <=> D-Tyr-Ala-His-Lys + L-lysine
|
3.4.17.10
carboxypeptidase E
|
–
|
|
|
BRENDA:
BS64972
|
|
|
|
furylacryloyl-Gly-Lys + H2O <=> furylacryloyl-Gly + L-lysine
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36766
|
|
|
|
kentsin + H2O <=> Thr-Pro-Arg + L-lysine
|
3.4.17.3
lysine carboxypeptidase
|
–
|
|
|
BRENDA:
BS36758
|
|
|
|
Lys-Leu-2-naphthylamide + H2O <=> L-lysine + Leu-2-naphthylamide
|
3.4.11.6
aminopeptidase B
|
–
|
|
|
BRENDA:
BS36319
|
|
|
|
Lys-Pro-Arg + H2O <=> L-lysine + Pro-Arg
|
3.4.11.9
Xaa-Pro aminopeptidase
|
–
|
|
|
BRENDA:
BS36364
|
|
|
|
Lys-Gly + H2O <=> L-lysine + glycine
|
3.4.11.10
bacterial leucyl aminopeptidase
3.4.13.19
membrane dipeptidase
|
–
–
|
|
|
BRENDA:
BS64770
|
|
|
|
Gly-Lys + H2O <=> glycine + L-lysine
|
3.4.22.40
bleomycin hydrolase
|
–
|
|
|
BRENDA:
BS37023
|
|
|
|
homoarginine + glycine |