|
|
L-glutamate + 7,8-dihydropteroate + ATP <=> H+ + 7,8-dihydrofolate + phosphate + ADP
|
6.3.2.12
dihydrofolate synthase
6.3.2.17
tetrahydrofolate synthase
|
–
–
|
BMK
|
|
BRENDA:
BR104
KEGG:
R02237
MetaCyc:
DIHYDROFOLATESYNTH-RXN
|
|
|
|
L-glutamate + L-cysteine + ATP <=> gamma-Glu-L-Cys + ADP + phosphate + H+
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
BMK
|
|
BRENDA:
BR112
KEGG:
R00894
MetaCyc:
GLUTCYSLIG-RXN
SABIO-RK:
1217
|
|
|
|
methylamine + L-glutamate + ATP <=> N5-Methyl-L-glutamine + phosphate + ADP + H+
|
6.3.1.2
glutamine synthetase
6.3.2.2
glutamate---cysteine ligase
6.3.4.12
glutamate---methylamine ligase
|
–
–
–
|
M
|
|
BRENDA:
BR133
KEGG:
R01585
MetaCyc:
GLUTAMATE--METHYLAMINE-LIGASE-RXN
SABIO-RK:
1735
|
|
|
|
ATP + deamido-NAD+ + L-glutamine + H2O <=> H+ + L-glutamate + AMP + diphosphate + NAD+
|
6.3.1.5
NAD+ synthase
6.3.5.1
NAD+ synthase (glutamine-hydrolysing)
|
–
–
|
BMK
|
|
BRENDA:
BR147
KEGG:
R00257
MetaCyc:
NAD-SYNTH-GLN-RXN
|
|
|
|
XMP + H2O + L-glutamine + ATP <=> H+ + L-glutamate + GMP + diphosphate + AMP
|
6.3.5.2
GMP synthase (glutamine-hydrolysing)
|
–
|
BMK
|
|
BRENDA:
BR149
KEGG:
R01231
MetaCyc:
GMP-SYN-GLUT-RXN
SABIO-RK:
215
|
|
|
|
ATP + formylglycinamide_ribonucleotide + L-glutamine + H2O <=> H+ + L-glutamate + ADP + phosphate + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine
|
6.3.5.3
phosphoribosylformylglycinamidine synthase
|
–
|
BMK
|
|
BRENDA:
BR150
KEGG:
R04463
MetaCyc:
FGAMSYN-RXN
|
|
|
|
ATP + L-aspartate + L-glutamine + H2O <=> AMP + diphosphate + L-asparagine + L-glutamate + H+
|
6.3.5.4
asparagine synthase (glutamine-hydrolysing)
|
–
|
BMK
|
|
BRENDA:
BR151
KEGG:
R00578
MetaCyc:
ASNSYNB-RXN
|
|
|
|
ATP + L-glutamine + HCO3- + H2O <=> L-glutamate + Carbamoyl_phosphate + ADP + phosphate + H+
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
BMK
|
|
BRENDA:
BR152
KEGG:
R00575
MetaCyc:
CARBPSYN-RXN
SABIO-RK:
203
|
|
|
|
L-glutamate <=> D-glutamate
|
5.1.1.10
amino-acid racemase
5.1.1.3
glutamate racemase
5.1.1.9
arginine racemase
|
–
–
–
|
BMK
|
|
BRENDA:
BR171
KEGG:
R00260
MetaCyc:
GLUTRACE-RXN
SABIO-RK:
765
|
|
|
|
L-glutamine + H2O <=> L-glutamate + NH3
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.14
glutamate synthase (NADH)
1.4.7.1
glutamate synthase (ferredoxin)
2.3.2.2
gamma-glutamyltransferase
2.4.2
2.4.2.14
amidophosphoribosyltransferase
3.4.11.17
tryptophanyl aminopeptidase
3.5.1.1
asparaginase
3.5.1.2
glutaminase
3.5.1.38
glutamin-(asparagin-)ase
3.5.1.43
peptidyl-glutaminase
3.5.1.44
protein-glutamine glutaminase
4.3.1.B2
4.3.2.10
imidazole glycerol-phosphate synthase
4.3.3.6
pyridoxal 5'-phosphate synthase (glutamine hydrolysing)
6.3.4.2
CTP synthase (glutamine hydrolysing)
6.3.5.13
lipid II isoglutaminyl synthase (glutamine-hydrolysing)
6.3.5.2
GMP synthase (glutamine-hydrolysing)
6.3.5.4
asparagine synthase (glutamine-hydrolysing)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
6.3.5.6
asparaginyl-tRNA synthase (glutamine-hydrolysing)
6.3.5.7
glutaminyl-tRNA synthase (glutamine-hydrolysing)
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR22683
KEGG:
R00256
MetaCyc:
GLUTAMIN-RXN
SABIO-RK:
762
|
|
|
|
L-Theanine + H2O <=> L-glutamate + ethylamine
|
2.3.2.9
agaritine gamma-glutamyltransferase
3.5.1.2
glutaminase
3.5.1.65
theanine hydrolase
6.3.4.12
glutamate---methylamine ligase
|
–
–
–
–
|
|
|
BRENDA:
BR22706;
BS407248
KEGG:
R02930
MetaCyc:
THEANINE-HYDROLASE-RXN
|
|
|
|
N-formyl-L-glutamate + H2O <=> L-glutamate + formate
|
3.5.1.68
N-formylglutamate deformylase
3.5.1.8
formylaspartate deformylase
|
–
–
|
BMK
|
|
BRENDA:
BR22707
KEGG:
R00525
MetaCyc:
N-FORMYLGLUTAMATE-DEFORMYLASE-RXN
|
|
|
|
5-oxoproline + H2O + ATP <=> H+ + L-glutamate + phosphate + ADP
|
3.5.2.9
5-oxoprolinase (ATP-hydrolysing)
|
–
|
BMK
|
|
BRENDA:
BR22721
KEGG:
R00251
MetaCyc:
5-OXOPROLINASE-ATP-HYDROLYSING-RXN
SABIO-RK:
759;
8623
|
|
|
|
H2O + N-formimino-L-glutamate <=> L-glutamate + Formamide
|
3.5.3.8
formimidoylglutamase
|
–
|
BMK
|
|
BRENDA:
BR26109
KEGG:
R02285
MetaCyc:
FORMIMINOGLUTAMASE-RXN
|
|
|
|
H+ + L-glutamate <=> CO2 + 4-aminobutanoate
|
4.1.1.15
glutamate decarboxylase
4.1.1.25
tyrosine decarboxylase
4.1.1.29
sulfinoalanine decarboxylase
|
–
–
–
|
BMK
|
|
BRENDA:
BR275
KEGG:
R00261
MetaCyc:
GLUTDECARBOX-RXN
SABIO-RK:
766
|
|
|
|
L-2,4-diaminobutanoate + 2-oxoglutarate <=> L-aspartate_4-semialdehyde + L-glutamate
|
2.6.1.46
diaminobutyrate---pyruvate transaminase
2.6.1.76
diaminobutyrate---2-oxoglutarate transaminase
4.1.1.86
diaminobutyrate decarboxylase
|
–
–
–
|
BMK
|
|
BRENDA:
BR29484
KEGG:
R06977
MetaCyc:
R101-RXN
SABIO-RK:
7483
|
|
|
|
L-threo-3-methylaspartate <=> L-glutamate
|
5.4.99.1
methylaspartate mutase
|
–
|
BMK
|
|
BRENDA:
BR33
KEGG:
R00262
MetaCyc:
METHYLASPARTATE-MUTASE-RXN
SABIO-RK:
767
|
|
|
|
chorismate + L-glutamine <=> H+ + anthranilate + L-glutamate + pyruvate
|
4.1.3.27
anthranilate synthase
|
–
|
BMK
|
|
BRENDA:
BR3373
KEGG:
R00986
MetaCyc:
ANTHRANSYN-RXN
SABIO-RK:
1280
|
|
|
|
L-glutamate + NADP+ <=> H+ + L-glutamine + 2-oxoglutarate + NADPH
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.B5
|
–
–
|
BMK
|
|
BRENDA:
BR36861
KEGG:
R00114
MetaCyc:
GLUTAMATESYN-RXN
SABIO-RK:
694
|
|
|
|
L-glutamate + NAD+ <=> L-glutamine + 2-oxoglutarate + NADH + H+
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.14
glutamate synthase (NADH)
|
–
–
|
BMK
|
|
BRENDA:
BR36862
KEGG:
R00093
MetaCyc:
GLUTAMATE-SYNTHASE-NADH-RXN
SABIO-RK:
675
|
|
|
|
NAD+ + H2O + L-glutamate <=> NADH + 2-oxoglutarate + NH3 + H+
|
1.4.1.14
glutamate synthase (NADH)
1.4.1.2
glutamate dehydrogenase
1.4.1.3
glutamate dehydrogenase [NAD(P)+]
1.4.1.4
glutamate dehydrogenase (NADP+)
1.4.1.5
L-amino-acid dehydrogenase
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR36868
KEGG:
R00243
MetaCyc:
GLUTAMATE-DEHYDROGENASE-NADP+-RXN_WOP;
GLUTAMATE-DEHYDROGENASE-RXN
SABIO-RK:
755
|
|
|
|
NADP+ + H2O + L-glutamate <=> NADPH + 2-oxoglutarate + NH3 + H+
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.2
glutamate dehydrogenase
1.4.1.3
glutamate dehydrogenase [NAD(P)+]
1.4.1.4
glutamate dehydrogenase (NADP+)
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR36869;
BS397591-a
KEGG:
R00248
MetaCyc:
GLUTAMATE-DEHYDROGENASE-NADP+-RXN;
GLUTDEHYD-RXN;
RXN-20084
SABIO-RK:
757
|
|
|
|
L-glutamate + H2O + O2 <=> 2-oxoglutarate + NH3 + H2O2
|
1.4.3.11
L-glutamate oxidase
1.4.3.16
L-aspartate oxidase
1.4.3.2
L-amino-acid oxidase
|
–
–
–
|
|
|
BRENDA:
BR36874
KEGG:
R00250
MetaCyc:
L-GLUTAMATE-OXIDASE-RXN
SABIO-RK:
758
|
|
|
|
L-glutamate + oxidized_ferredoxin <=> 2-oxoglutarate + L-glutamine + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.4.7.1
glutamate synthase (ferredoxin)
|
–
|
BMK
|
|
BRENDA:
BR36886
KEGG:
R00021
MetaCyc:
GLUTAMATE-SYNTHASE-FERREDOXIN-RXN
|
|
|
|
L-glutamate_5-semialdehyde + H2O + NAD+ <=> L-glutamate + NADH + H+
|
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.41
glutamate-5-semialdehyde dehydrogenase
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR36889
KEGG:
R00245
MetaCyc:
RXN-14116
SABIO-RK:
11705;
756
|
|
|
|
saccharopine + H2O + NAD+ <=> L-glutamate + (S)-2-amino-6-oxohexanoate + NADH + H+
|
1.5.1.9
saccharopine dehydrogenase (NAD+, L-glutamate-forming)
|
–
|
BMK
|
|
BRENDA:
BR37178;
BS261177
KEGG:
R02313
MetaCyc:
1.5.1.9-RXN
SABIO-RK:
2273
|
|
|
|
H2O + acceptor + N-Methyl-L-glutamate <=> L-glutamate + reduced_acceptor + formaldehyde
|
1.5.99.5
methylglutamate dehydrogenase
|
–
|
MK
|
|
BRENDA:
BR40352
KEGG:
R00609
MetaCyc:
METHYLGUTAMATE-DEHYDROGENASE-RXN
|
|
|
|
saccharopine + NADP+ + H2O <=> H+ + L-glutamate + (S)-2-amino-6-oxohexanoate + NADPH
|
1.5.1.10
saccharopine dehydrogenase (NADP+, L-glutamate-forming)
|
–
|
BMK
|
|
BRENDA:
BR40355;
BS287686
KEGG:
R02315
MetaCyc:
RXN3O-127
|
|
|
|
methylamine + L-glutamate <=> N-Methyl-L-glutamate + NH3
|
2.1.1.21
methylamine---glutamate N-methyltransferase
|
–
|
BK
|
|
BRENDA:
BR43888
KEGG:
R01586
MetaCyc:
2.1.1.21-RXN
|
|
|
|
L-glutamate + acetyl-CoA <=> H+ + N-acetyl-L-glutamate + CoA
|
2.3.1.1
amino-acid N-acetyltransferase
2.3.1.17
aspartate N-acetyltransferase
2.3.1.183
phosphinothricin acetyltransferase
2.7.2.8
acetylglutamate kinase
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR43962
KEGG:
R00259
MetaCyc:
N-ACETYLTRANSFER-RXN
SABIO-RK:
764
|
|
|
|
L-glutamate + N2-Acetyl-L-ornithine <=> N-acetyl-L-glutamate + L-ornithine
|
2.3.1.35
glutamate N-acetyltransferase
|
–
|
BMK
|
|
BRENDA:
BR44035
KEGG:
R02282
MetaCyc:
GLUTAMATE-N-ACETYLTRANSFERASE-RXN
SABIO-RK:
2247
|
|
|
|
5-phosphoribosylamine + diphosphate + L-glutamate <=> 5-phospho-alpha-D-ribose_1-diphosphate + L-glutamine + H2O
|
2.4.2.14
amidophosphoribosyltransferase
|
–
|
BMK
|
|
BRENDA:
BR44270
KEGG:
R01072
MetaCyc:
PRPPAMIDOTRANS-RXN
SABIO-RK:
114
|
|
|
|
L-glutamine + L-Glutamyl-tRNA(Gln) + ATP + H2O <=> L-glutamate + glutaminyl-tRNAGln + phosphate + ADP + H+
|
6.3.5.6
asparaginyl-tRNA synthase (glutamine-hydrolysing)
6.3.5.7
glutaminyl-tRNA synthase (glutamine-hydrolysing)
|
–
–
|
BK
|
|
BRENDA:
BR44353
KEGG:
R03905
MetaCyc:
6.3.5.7-RXN
SABIO-RK:
3650
|
|
|
|
L-kynurenine + 2-oxoglutarate <=> L-glutamate + 4-(2-aminophenyl)-2,4-dioxobutanoate
|
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.75
cysteine-conjugate transaminase
|
–
–
|
BMK
|
|
BRENDA:
BR47389
KEGG:
R01956
MetaCyc:
2.6.1.7-RXN
SABIO-RK:
2003
|
|
|
|
taurine + 2-oxoglutarate <=> L-glutamate + 2-sulfoacetaldehyde
|
2.6.1.55
taurine---2-oxoglutarate transaminase
|
–
|
MK
|
|
BRENDA:
BR47391
KEGG:
R01684
MetaCyc:
RXN-2301
|
|
|
|
L-Dopa + 2-oxoglutarate <=> 3,4-Dihydroxyphenylpyruvate + L-glutamate
|
2.6.1.27
tryptophan transaminase
2.6.1.49
dihydroxyphenylalanine transaminase
2.6.1.5
tyrosine transaminase
|
–
–
–
|
MK
|
|
BRENDA:
BR47392
KEGG:
R02077
MetaCyc:
2.6.1.49-RXN
SABIO-RK:
2087
|
|
|
|
2-oxoglutarate + L-alanine <=> L-glutamate + pyruvate
|
2.6.1.1
aspartate transaminase
2.6.1.12
alanine---oxo-acid transaminase
2.6.1.2
alanine transaminase
2.6.1.37
2-aminoethylphosphonate---pyruvate transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.4
glycine transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47397
KEGG:
R00258
MetaCyc:
ALANINE-AMINOTRANSFERASE-RXN;
RXN-13698
SABIO-RK:
763
|
|
|
|
2-oxoglutarate + N-succinyl-LL-2,6-diaminoheptanedioate <=> L-glutamate + N-succinyl-L-2-amino-6-oxoheptanedioate
|
2.6.1.17
succinyldiaminopimelate transaminase
|
–
|
BMK
|
|
BRENDA:
BR47417
KEGG:
R04475
MetaCyc:
SUCCINYLDIAMINOPIMTRANS-RXN
|
|
|
|
dTDP-4-amino-4,6-dideoxy-D-galactose + 2-oxoglutarate <=> dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate
|
2.6.1.33
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase
2.6.1.59
dTDP-4-amino-4,6-dideoxygalactose transaminase
|
–
–
|
MK
|
|
BRENDA:
BR47421
KEGG:
R04438
MetaCyc:
RFFTRANS-RXN
|
|
|
|
2-oxoglutarate + D-4-hydroxyphenylglycine <=> L-glutamate + 4-hydroxyphenylglyoxylate
|
2.6.1.72
D-4-hydroxyphenylglycine transaminase
|
–
|
|
|
BRENDA:
BR47429
KEGG:
R04234
MetaCyc:
2.6.1.72-RXN
|
|
|
|
6-Acetamido-3-aminohexanoate + 2-oxoglutarate <=> L-glutamate + 6-Acetamido-3-oxohexanoate
|
2.6.1.65
N6-acetyl-beta-lysine transaminase
|
–
|
|
|
BRENDA:
BR47431
KEGG:
R04028
MetaCyc:
2.6.1.65-RXN
|
|
|
|
2-oxoglutarate + L-lysine <=> L-glutamate + (S)-2-amino-6-oxohexanoate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.36
L-lysine 6-transaminase
|
–
–
|
BM
|
|
BRENDA:
BR47436;
BS354059
KEGG:
R00457
MetaCyc:
L-LYSINE-AMINOTRANSFERASE-RXN
SABIO-RK:
894
|
|
|
|
4-aminobutanoate + 2-oxoglutarate <=> succinate_semialdehyde + L-glutamate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.22
(S)-3-amino-2-methylpropionate transaminase
2.6.1.29
diamine transaminase
2.6.1.48
5-aminovalerate transaminase
|
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47437
KEGG:
R01648
MetaCyc:
GABATRANSAM-RXN
SABIO-RK:
1785
|
|
|
|
L-Histidinol_phosphate + 2-oxoglutarate <=> 3-(Imidazol-4-yl)-2-oxopropyl_phosphate + L-glutamate
|
2.6.1.9
histidinol-phosphate transaminase
|
–
|
BMK
|
|
BRENDA:
BR47443
KEGG:
R03243
MetaCyc:
HISTAMINOTRANS-RXN
SABIO-RK:
3064
|
|
|
|
2-oxoglutarate + L-ornithine <=> L-glutamate + 5-amino-2-oxopentanoate
|
2.6.1.8
2,5-diaminovalerate transaminase
|
–
|
BM
|
|
BRENDA:
BR47495;
BS354658
KEGG:
R03248
MetaCyc:
25-DIAMINOVALERATE-AMINOTRANSFERASE-RXN
|
|
|
|
L-aspartate + 2-oxoglutarate <=> oxaloacetate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.75
cysteine-conjugate transaminase
2.6.1.78
aspartate---prephenate aminotransferase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47671;
BS377429
KEGG:
R00355
MetaCyc:
ASPAMINOTRANS-RXN;
RXN-13697
SABIO-RK:
825
|
|
|
|
beta-D-fructose_6-phosphate + L-glutamine <=> D-glucose_6-phosphate + L-glutamate
|
2.6.1.16
glutamine---fructose-6-phosphate transaminase (isomerizing)
|
–
|
MK
|
|
BRENDA:
BR47674
KEGG:
R00768
MetaCyc:
L-GLN-FRUCT-6-P-AMINOTRANS-RXN
SABIO-RK:
33
|
|
|
|
2-oxoglutarate + L-erythro-4-hydroxyglutamate <=> L-glutamate + (D)-4-hydroxy-alpha-ketoglutarate
|
2.6.1.1
aspartate transaminase
2.6.1.23
4-hydroxyglutamate transaminase
|
–
–
|
MK
|
|
BRENDA:
BR47675;
BS452218
KEGG:
R05052
MetaCyc:
4-HYDROXYGLUTAMATE-AMINOTRANSFERASE-RXN
|
|
|
|
2-oxoglutarate + 3,5-diiodo-L-tyrosine <=> L-glutamate + 3,5-diiodo-4-hydroxyphenylpyruvate
|
2.6.1.24
diiodotyrosine transaminase
2.6.1.26
thyroid-hormone transaminase
|
–
–
|
|
|
BRENDA:
BR47676
KEGG:
R03207
MetaCyc:
DIIODOTYROSINE-AMINOTRANSFERASE-RXN
|
|
|
|
3,5,3''-triiodo-L-thyronine + 2-oxoglutarate <=> L-glutamate + 3,5,3''-triiodothyropyruvate
|
2.6.1.26
thyroid-hormone transaminase
|
–
|
|
|
BRENDA:
BR47677
KEGG:
R03952
MetaCyc:
THYROID-HORMONE-AMINOTRANSFERASE-RXN
|
|
|
|
L-tryptophan + 2-oxoglutarate <=> 3-Indole-2-oxopropanoate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.24
diiodotyrosine transaminase
2.6.1.26
thyroid-hormone transaminase
2.6.1.27
tryptophan transaminase
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47678
KEGG:
R00684
MetaCyc:
TRYPTOPHAN-AMINOTRANSFERASE-RXN
SABIO-RK:
1064
|
|
|
|
putrescine + 2-oxoglutarate <=> L-glutamate + Aliphatic-Omega-Amino-Aldehydes
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.29
diamine transaminase
2.6.1.82
putrescine---2-oxoglutarate transaminase
|
–
–
–
|
MK
|
|
BRENDA:
BR47680;
BR48746
KEGG:
R01155;
R07275
MetaCyc:
DIAMTRANSAM-RXN;
PUTTRANSAM-RXN
|
|
|
|
L-cysteine + 2-oxoglutarate <=> 3-Mercaptopyruvate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.3
cysteine transaminase
2.6.1.5
tyrosine transaminase
|
–
–
–
|
BMK
|
|
BRENDA:
BR47681
KEGG:
R00895;
R00896
MetaCyc:
CYSTEINE-AMINOTRANSFERASE-RXN
|
|
|
|
2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-alpha-D-glucopyranose <=> L-glutamate + dTDP-4-dehydro-6-deoxy-D-glucose
|
2.6.1.33
dTDP-4-amino-4,6-dideoxy-D-glucose transaminase
2.6.1.B6
|
–
–
|
BMK
|
|
BRENDA:
BR47685
KEGG:
R02773
MetaCyc:
2.6.1.33-RXN
|
|
|
|
UDP-4-amino-4,6-dideoxy-N-acetyl-alpha-D-glucosamine + 2-oxoglutarate <=> UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose + L-glutamate
|
2.6.1.34
UDP-N-acetylbacillosamine transaminase
|
–
|
MK
|
|
BRENDA:
BR47686
KEGG:
R04529
MetaCyc:
RXN-12812
|
|
|
|
L-histidine + 2-oxoglutarate <=> L-glutamate + 3-(1H-imidazol-4-yl)-2-oxopropanoate
|
2.6.1.27
tryptophan transaminase
2.6.1.38
histidine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47688
KEGG:
R01161
MetaCyc:
HISTTRANSAM-RXN
|
|
|
|
L-2-aminoadipate + 2-oxoglutarate <=> L-glutamate + 2-oxoadipate
|
2.6.1.39
2-aminoadipate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
|
BMK
|
|
BRENDA:
BR47689
KEGG:
R01939
MetaCyc:
2-AMINOADIPATE-AMINOTRANSFERASE-RXN
SABIO-RK:
1992
|
|
|
|
glycine + 2-oxoglutarate <=> glyoxylate + L-glutamate
|
2.6.1.2
alanine transaminase
2.6.1.4
glycine transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.48
5-aminovalerate transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47690
KEGG:
R00372
MetaCyc:
GLYCINE-AMINOTRANSFERASE-RXN
SABIO-RK:
839
|
|
|
|
L-leucine + 2-oxoglutarate <=> L-glutamate + 4-methyl-2-oxopentanoate
|
2.6.1.1
aspartate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.6
leucine transaminase
2.6.1.67
2-aminohexanoate transaminase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47691
KEGG:
R01090
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERLEU-RXN
SABIO-RK:
1352
|
|
|
|
5-Aminopentanoate + 2-oxoglutarate <=> L-glutamate + 5-Oxopentanoate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.48
5-aminovalerate transaminase
|
–
–
–
|
BMK
|
|
BRENDA:
BR47695
KEGG:
R02274
MetaCyc:
VAGL-RXN
|
|
|
|
L-tyrosine + 2-oxoglutarate <=> 4-hydroxyphenylpyruvate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.2
alanine transaminase
2.6.1.24
diiodotyrosine transaminase
2.6.1.27
tryptophan transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.49
dihydroxyphenylalanine transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.79
glutamate---prephenate aminotransferase
2.6.1.9
histidinol-phosphate transaminase
|
–
–
–
–
–
–
–
–
–
–
–
–
|
BMK
|
|
BRENDA:
BR47696
KEGG:
R00734
MetaCyc:
TYROSINE-AMINOTRANSFERASE-RXN
SABIO-RK:
1097
|
|
|
|
O-phospho-L-serine + 2-oxoglutarate <=> L-glutamate + 3-phosphohydroxypyruvate
|
2.6.1.52
phosphoserine transaminase
|
–
|
BMK
|
|
BRENDA:
BR47699
KEGG:
R04173
MetaCyc:
PSERTRANSAM-RXN
SABIO-RK:
3893
|
|
|
|
2-oxoglutarate + L-norleucine <=> L-glutamate + 2-Oxohexanoate
|
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.48
5-aminovalerate transaminase
2.6.1.67
2-aminohexanoate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
–
–
–
|
|
|
BRENDA:
BR47704
KEGG:
R03053
MetaCyc:
2-AMINOHEXANOATE-AMINOTRANSFERASE-RXN
|
|
|
|
2-oxoglutarate + S-(4-Bromophenyl)-L-cysteine <=> L-glutamate + S-(4-Bromophenyl)-3-thiopyruvate
|
2.6.1.75
cysteine-conjugate transaminase
|
–
|
|
|
BRENDA:
BR47709
KEGG:
R04338
MetaCyc:
CYSTEINE-CONJUGATE-TRANSAMINASE-RXN
|
|
|
|
L-glutamate + ATP <=> L-5-glutamyl_phosphate + ADP
|
2.7.2.11
glutamate 5-kinase
|
–
|
BMK
|
|
BRENDA:
BR47821
KEGG:
R00239
MetaCyc:
GLUTKIN-RXN
SABIO-RK:
752
|
|
|
|
chorismate + L-glutamine <=> 4-amino-4-deoxychorismate + L-glutamate
|
2.6.1.85
aminodeoxychorismate synthase
|
–
|
BMK
|
|
BRENDA:
BR47979
KEGG:
R01716
MetaCyc:
PABASYN-RXN
SABIO-RK:
1828
|
|
|
|
adenosylcobyrinic_acid_a,c-diamide + L-glutamine + ATP + H2O <=> H+ + L-glutamate + adenosylcobyric_acid + ADP + phosphate
|
6.3.5.10
adenosylcobyric acid synthase (glutamine-hydrolysing)
|
–
|
BMK
|
|
BRENDA:
BR48011
KEGG:
R05225
MetaCyc:
R345-RXN
|
|
|
|
Hydrogenobyrinate + L-glutamine + ATP + H2O <=> H+ + L-glutamate + hydrogenobyrinic_acid_a,c-diamide + ADP + phosphate
|
6.3.5.11
cobyrinate a,c-diamide synthase
6.3.5.9
hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
|
–
–
|
BMK
|
|
BRENDA:
BR48014
KEGG:
R05224
MetaCyc:
R341-RXN
SABIO-RK:
4835
|
|
|
|
N2-Acetyl-L-ornithine + 2-oxoglutarate <=> L-glutamate + N-acetyl-L-glutamate_5-semialdehyde
|
2.6.1.11
acetylornithine transaminase
2.6.1.13
ornithine aminotransferase
|
–
–
|
BMK
|
|
BRENDA:
BR48055
KEGG:
R02283
MetaCyc:
ACETYLORNTRANSAM-RXN
SABIO-RK:
2248
|
|
|
|
ATP + UTP + L-glutamine + H2O <=> H+ + ADP + phosphate + CTP + L-glutamate
|
6.3.4.2
CTP synthase (glutamine hydrolysing)
|
–
|
BMK
|
|
BRENDA:
BR48389
KEGG:
R00573
MetaCyc:
CTPSYN-RXN
SABIO-RK:
459
|
|
|
|
putrescine + L-glutamate + ATP <=> H+ + gamma-L-glutamylputrescine + ADP + phosphate
|
6.3.1.11
glutamate---putrescine ligase
|
–
|
BMK
|
|
BRENDA:
BR48542
KEGG:
R07414
MetaCyc:
RXN0-3901
|
|
|
|
nicotianamine + 2-oxoglutarate <=> L-glutamate + 3''''-deamino-3''''-oxonicotianamine
|
2.6.1.80
nicotianamine aminotransferase
|
–
|
M
|
|
BRENDA:
BR48543
KEGG:
R07277
MetaCyc:
2.6.1.80-RXN
|
|
|
|
L-arogenate + 2-oxoglutarate <=> prephenate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.78
aspartate---prephenate aminotransferase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
|
BMK
|
|
BRENDA:
BR48630
KEGG:
R07276
MetaCyc:
PREPHENATE-TRANSAMINE-RXN
SABIO-RK:
9205
|
|
|
|
N2-succinyl-L-ornithine + 2-oxoglutarate <=> L-glutamate + N-succinyl-L-glutamate_5-semialdehyde
|
2.6.1.11
acetylornithine transaminase
2.6.1.81
succinylornithine transaminase
|
–
–
|
BMK
|
|
BRENDA:
BR48672
KEGG:
R04217
MetaCyc:
SUCCORNTRANSAM-RXN
|
|
|
|
4-(glutamylamino)_butanoate + H2O <=> L-glutamate + 4-aminobutanoate
|
3.5.1.94
gamma-glutamyl-gamma-aminobutyrate hydrolase
|
–
|
BMK
|
|
BRENDA:
BR48700
KEGG:
R07419
MetaCyc:
RXN0-3942
|
|
|
|
LL-2,6-Diaminoheptanedioate + 2-oxoglutarate <=> (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + L-glutamate + H2O + H+
|
2.6.1.83
LL-diaminopimelate aminotransferase
|
–
|
BMK
|
|
BRENDA:
BR48748;
BS424856
KEGG:
R07613
MetaCyc:
RXN-7737
SABIO-RK:
12290
|
|
|
|
chorismate + L-glutamine <=> (2S)-2-amino-4-deoxy-chorismate + L-glutamate
|
2.6.1.85
aminodeoxychorismate synthase
2.6.1.86
2-amino-4-deoxychorismate synthase
|
–
–
|
MK
|
|
BRENDA:
BR48884
KEGG:
R08956
MetaCyc:
RXN-9028
SABIO-RK:
15416
|
|
|
|
H2O + 4-aminobenzoyl_glutamic_acid <=> 4-Aminobenzoic_acid + L-glutamate
|
3.4.19.9
folate gamma-glutamyl hydrolase
3.5.1
3.5.1.32
hippurate hydrolase
3.5.1.B18
|
–
–
–
–
|
|
|
BRENDA:
BR48940
MetaCyc:
RXN0-5040
|
|
|
|
UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate <=> UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate
|
2.6.1.87
UDP-4-amino-4-deoxy-L-arabinose aminotransferase
2.6.1.92
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase
|
–
–
|
MK
|
|
BRENDA:
BR49185
KEGG:
R07659
MetaCyc:
RXN0-1863
|
|
|
|
5,6,7,8-tetrahydromethanopterin + L-glutamate + ATP <=> H+ + tetrahydrosarcinapterin + ADP + phosphate
|
6.3.2.33
tetrahydrosarcinapterin synthase
|
–
|
BK
|
|
BRENDA:
BR49212
KEGG:
R09594
MetaCyc:
RXN-11103
|
|
|
|
saccharopine + O2 + H2O <=> (S)-2-amino-6-oxohexanoate + L-glutamate + H2O2
|
1.5.3.18
L-saccharopine oxidase
|
–
|
|
|
BRENDA:
BR49438
KEGG:
R09495
MetaCyc:
RXN-10744
SABIO-RK:
12707
|
|
|
|
cobyrinate + L-glutamine + ATP + H2O <=> cob(II)yrinic_acid_a,c-diamide + L-glutamate + ADP + phosphate + H+
|
6.3.5.11
cobyrinate a,c-diamide synthase
6.3.5.9
hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
|
–
–
|
BMK
|
|
BRENDA:
BR49510
KEGG:
R05815
MetaCyc:
RXN-8769
SABIO-RK:
6681
|
|
|
|
cobyrinate + L-glutamine + ATP + H2O <=> cobyrinic_acid_c-monoamide + L-glutamate + ADP + phosphate + H+
|
6.3.5.11
cobyrinate a,c-diamide synthase
|
–
|
|
|
BRENDA:
BR49517
KEGG:
R09598
MetaCyc:
RXN-14256
|
|
|
|
cobyrinic_acid_c-monoamide + L-glutamine + ATP + H2O <=> cob(II)yrinic_acid_a,c-diamide + L-glutamate + ADP + phosphate + H+
|
6.3.5.11
cobyrinate a,c-diamide synthase
6.3.5.9
hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
|
–
–
|
|
|
BRENDA:
BR49518
KEGG:
R09599
MetaCyc:
RXN-14257
|
|
|
|
glutathione + H2O <=> Cys-Gly + L-glutamate
|
2.3.2.2
gamma-glutamyltransferase
3.4.19.13
glutathione gamma-glutamate hydrolase
3.5.1.93
glutaryl-7-aminocephalosporanic-acid acylase
|
–
–
–
|
BMK
|
|
BRENDA:
BR49838
KEGG:
R00494
MetaCyc:
RXN-12618
SABIO-RK:
926
|
|
|
|
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + 2-oxoglutarate <=> dTDP-3-dehydro-6-deoxy-alpha-D-glucopyranose + L-glutamate
|
2.6.1.89
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase
|
–
|
MK
|
|
BRENDA:
BR49899
KEGG:
R06423
MetaCyc:
RXN-12810
|
|
|
|
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose + 2-oxoglutarate <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose + L-glutamate
|
2.6.1.90
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose transaminase
|
–
|
MK
|
|
BRENDA:
BR49900
KEGG:
R09824
MetaCyc:
RXN-12811
|
|
|
|
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine + 2-oxoglutarate <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate
|
2.6.1.92
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase
|
–
|
MK
|
|
BRENDA:
BR49902
KEGG:
R09825
MetaCyc:
RXN-9999
|
|
|
|
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose + 2-oxoglutarate <=> dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucopyranose + L-glutamate
|
2.6.1.106
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
|
–
|
BMK
|
|
BRENDA:
BR49904
KEGG:
R06426
MetaCyc:
RXN-12768
|
|
|
|
L-glutamate + oxidized_ferredoxin + H2O <=> NH3 + 2-oxoglutarate + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.4.7.1
glutamate synthase (ferredoxin)
|
–
|
|
|
BRENDA:
BR49966
KEGG:
R10086
MetaCyc:
RXN-12878
|
|
|
|
leukotriene_C4 + H2O <=> leukotriene_D4 + L-glutamate
|
3.4.19.14
leukotriene-C4 hydrolase
|
–
|
BK
|
|
BRENDA:
BR49989
KEGG:
R09875
MetaCyc:
RXN-12825
|
|
|
|
neamine + 2-oxoglutarate <=> 6''-dehydroparomamine + L-glutamate
|
2.6.1.93
neamine transaminase
|
–
|
MK
|
|
BRENDA:
BR50192
KEGG:
R08897
MetaCyc:
RXN-13146
|
|
|
|
2''-deamino-2''-hydroxy-6''-dehydroparomamine + L-glutamate <=> 2''-deamino-2''-hydroxyneamine + 2-oxoglutarate
|
2.6.1.94
2'-deamino-2'-hydroxyneamine transaminase
|
–
|
MK
|
|
BRENDA:
BR50193
KEGG:
R10094
MetaCyc:
RXN-13127
|
|
|
|
neomycin_C + 2-oxoglutarate <=> 6''''''-deamino-6''''''-oxoneomycin_C + L-glutamate
|
2.6.1.95
neomycin C transaminase
|
–
|
MK
|
|
BRENDA:
BR50194
KEGG:
R08903
MetaCyc:
RXN-13175
|
|
|
|
L-glutamate <=> 3-aminopentanedioate
|
5.4.3.9
glutamate 2,3-aminomutase
|
–
|
|
|
BRENDA:
BR50211
KEGG:
R10153
MetaCyc:
RXN-13569
|
|
|
|
UDP-2-acetamido-3-amino-2,3-dideoxy-alpha-D-glucuronate + 2-oxoglutarate <=> UDP-2-acetamido-2-deoxy-alpha-D-ribo-hex-3-uluronate + L-glutamate
|
2.6.1.98
UDP-2-acetamido-2-deoxy-ribo-hexuluronate aminotransferase
|
–
|
MK
|
|
BRENDA:
BR50307
KEGG:
R10141
MetaCyc:
RXN-13596
|
|
|
|
putrescine + 2-oxoglutarate <=> DELTA1-pyrroline + L-glutamate + H2O
|
2.6.1.82
putrescine---2-oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BR50354
KEGG:
R10064
MetaCyc:
2.6.1.82-RXN
SABIO-RK:
12833
|
|
|
|
GDP-4-amino-4,6-dideoxy-alpha-D-mannose + 2-oxoglutarate <=> GDP-4-dehydro-6-deoxy-D-mannose + L-glutamate
|
2.6.1.102
GDP-perosamine synthase
|
–
|
BMK
|
|
BRENDA:
BR50674
KEGG:
R10460
MetaCyc:
RXN-8953
|
|
|
|
(S)-3,5-dihydroxyphenylglycine + 2-oxoglutarate <=> (3,5-dihydroxyphenyl)(oxo)acetate + L-glutamate
|
2.6.1.103
(S)-3,5-dihydroxyphenylglycine transaminase
|
–
|
K
|
|
BRENDA:
BR50675
KEGG:
R06634
MetaCyc:
RXN-14845
|
|
|
|
ATP + citrate + L-glutamate <=> ADP + phosphate + beta-Citryl-L-glutamate + H+
|
6.3.1.17
beta-citrylglutamate synthase
6.3.2.B11
|
–
–
|
K
|
|
BRENDA:
BR50904
KEGG:
R10677
MetaCyc:
RXN-15266
|
|
|
|
N-acetyl-L-aspartate + L-glutamate + ATP <=> N-Acetyl-L-Asp-L-Glu + ADP + phosphate + H+
|
6.3.2.41
N-acetylaspartylglutamate synthase
6.3.2.42
N-acetylaspartylglutamylglutamate synthase
|
–
–
|
K
|
|
BRENDA:
BR50905
KEGG:
R10678
MetaCyc:
RXN-15265
|
|
|
|
kanosamine_6-phosphate + 2-oxoglutarate <=> 3-dehydro-D-glucose_6-phosphate + L-glutamate
|
2.6.1.104
3-dehydro-glucose-6-phosphate---glutamate transaminase
|
–
|
BMK
|
|
BRENDA:
BR50964
KEGG:
R10698
MetaCyc:
RXN8J2-137
|
|
|
|
(2S,3S)-3-methylphenylalanine + 2-oxoglutarate <=> (3S)-2-oxo-3-phenylbutanoate + L-glutamate
|
2.6.1.107
beta-methylphenylalanine transaminase
2.6.1.57
aromatic-amino-acid transaminase
|
–
–
|
|
|
BRENDA:
BR50966
KEGG:
R10845
MetaCyc:
|