|
|
I- + H2O2 + H+ <=> Iodine + H2O
|
1.11.1.8
iodide peroxidase
|
–
|
|
|
BRENDA:
BR40492
KEGG:
R02810
MetaCyc:
IODIDE-PEROXIDASE-RXN
|
|
|
|
3,3,5''-triiodo-L-thyronine + I- + acceptor + H+ <=> L-thyroxine + reduced_acceptor
|
1.21.99.3
thyroxine 5-deiodinase
1.21.99.4
thyroxine 5'-deiodinase
|
–
–
|
M
|
|
BRENDA:
BR47629;
BR48042;
BS356010;
BS356011
KEGG:
R03734;
R07230
MetaCyc:
1.97.1.11-RXN;
THYROXINE-DEIODINASE-RXN
SABIO-RK:
3494;
9212
|
|
|
|
L-tyrosine + NADP+ + I- <=> 3-iodo-L-tyrosine + NADPH
|
1.21.1.1
iodotyrosine deiodinase
|
–
|
|
|
BRENDA:
BR49225;
BR51397
KEGG:
R09521;
R10059
MetaCyc:
RXN-11330;
RXN-13402
|
|
|
|
3-iodo-L-tyrosine + I- + NADP+ <=> 3,5-diiodo-L-tyrosine + NADPH + H+
|
1.21.1.1
iodotyrosine deiodinase
|
–
|
|
|
BRENDA:
BR49226
KEGG:
R09522
MetaCyc:
RXN-11331
|
|
|
|
S-adenosyl-L-methionine + I- <=> S-adenosyl-L-homocysteine + iodomethane
|
2.1.1.165
methyl halide transferase
2.1.1.9
thiol S-methyltransferase
|
–
–
|
M
|
|
BRENDA:
BR49560
KEGG:
R09523
MetaCyc:
RXN-11241
|
|
|
|
o-Iodobenzoate + NADH + H+ + O2 <=> catechol + I- + NAD+ + CO2
|
1.14.12.13
2-halobenzoate 1,2-dioxygenase
|
–
|
|
|
BRENDA:
BS288613
MetaCyc:
RXN-10444
|
|
|
|
3,3,5''-triiodo-L-thyronine + reduced_acceptor <=> 3,3''-diiodothyronine + I- + acceptor + H+
|
1.21.99.3
thyroxine 5-deiodinase
1.21.99.4
thyroxine 5'-deiodinase
|
–
–
|
M
|
|
BRENDA:
BS356012;
BS356013;
BS442171
MetaCyc:
RXN-10604;
RXN-10605;
RXN-12034;
RXN-12036
SABIO-RK:
9653;
9839
|
|
|
|
2,4-dinitro-1-iodobenzene + glutathione <=> S-(2,4-dinitrophenyl)glutathione + I-
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS378889
SABIO-RK:
13497
|
|
|
|
2-Methoxyorsellinate-[acp] + I- <=> 5-Iodo-2-methoxyorsellinate-[acp]
|
not assigned
|
–
|
K
|
|
KEGG:
R11414
|
|
|
|
[thyroglobulin]-L-tyrosine + I- + H2O2 + H+ <=> [thyroglobulin]-3-iodotyrosine + H2O
|
1.11.1.8
iodide peroxidase
|
–
|
M
|
|
MetaCyc:
RXN-10468
|
|
|
|
[thyroglobulin]-3-iodotyrosine + I- + H2O2 + H+ <=> [thyroglobulin]-3,5-diiodotyrosine + H2O
|
1.11.1.8
iodide peroxidase
|
–
|
M
|
|
MetaCyc:
RXN-10469
|
|
|
|
organic_molecule + I- + H2O2 + H+ <=> iodo_organic_compound + H2O
|
1.11.1
|
–
|
|
|
MetaCyc:
RXN-11337
|
|
|
|
3,3''-diiodothyronine + reduced_acceptor <=> 3-iodothyronine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12030
|
|
|
|
3-iodothyronine + reduced_acceptor <=> L-thyronine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12031
|
|
|
|
3,3''-diiodothyronine + reduced_acceptor <=> 3''-monoiodothyronine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12032
|
|
|
|
3''-monoiodothyronine + reduced_acceptor <=> L-thyronine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12033
|
|
|
|
diiodothyronine + reduced_acceptor <=> 3-iodothyronine + acceptor + I- + H+
|
1.21.99.3
thyroxine 5-deiodinase
|
–
|
M
|
|
MetaCyc:
RXN-12035
|
|
|
|
3,5''-diiodothyronine + reduced_acceptor <=> 3''-monoiodothyronine + acceptor + I- + H+
|
1.21.99.4
thyroxine 5'-deiodinase
|
–
|
M
|
|
MetaCyc:
RXN-12037
|
|
|
|
3,3,5,5''-tetraiodothyronamine + reduced_acceptor <=> 3,3,5-triiodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12043
|
|
|
|
3,3,5,5''-tetraiodothyronamine + reduced_acceptor <=> 3,3,5''-triiodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12044
|
|
|
|
3,3,5-triiodothyronamine + reduced_acceptor <=> 3,3''-diiodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12045
|
|
|
|
3,3,5''-triiodothyronamine + reduced_acceptor <=> 3,3''-diiodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12046
|
|
|
|
3,3''-diiodothyronamine + reduced_acceptor <=> 3-iodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12047
|
|
|
|
3,3''-diiodothyronamine + reduced_acceptor <=> 3''-iodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12048
|
|
|
|
3-iodothyronamine + reduced_acceptor <=> thyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12049
|
|
|
|
3''-iodothyronamine + reduced_acceptor <=> thyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12050
|
|
|
|
3,3,5-triiodothyronamine + reduced_acceptor <=> 3,5-diiodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12051
|
|
|
|
3,5-diiodothyronamine + reduced_acceptor <=> 3-iodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12052
|
|
|
|
3,3,5''-triiodothyronamine + reduced_acceptor <=> 3,5''-diiodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12053
|
|
|
|
3,5''-diiodothyronamine + reduced_acceptor <=> 3''-iodothyronamine + acceptor + I- + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12054
|
|
|
|
CH2ClI + H2O <=> formaldehyde + Cl- + I-
|
4.5.1.3
dichloromethane dehalogenase
|
–
|
|
|
BRENDA:
BS363529
|
|
|
|
L-tyrosine + H2O2 + I- <=> 3-iodo-L-tyrosine + 3,5-diiodo-L-tyrosine + H2O
|
1.11.1.8
iodide peroxidase
|
–
|
|
|
BRENDA:
BS289004
|
|
|
|
3-iodo-L-tyrosine + H2O2 + I- <=> 3-iodo-L-tyrosine + 3,5-diiodo-L-tyrosine + H2O
|
1.11.1.8
iodide peroxidase
|
–
|
|
|
BRENDA:
BS289005
|
|
|
|
pyrazole + I- + H2O2 <=> 4-iodopyrazole + H2O
|
1.11.1.10
chloride peroxidase
1.11.1.18
bromide peroxidase
|
–
–
|
|
|
BRENDA:
BS231278
|
|
|
|
I- + H2O2 + H+ <=> HIO + H2O
|
1.11.1.B2
1.11.2.2
myeloperoxidase
|
–
–
|
|
|
BRENDA:
BS413416
|
|
|
|
6-iodopurine + H2O <=> hypoxanthine + I-
|
3.5.4.2
adenine deaminase
|
–
|
|
|
BRENDA:
BS116414
|
|
|
|
Uracil + I- + H2O2 <=> 5-Iodouracil + H2O
|
1.11.1.10
chloride peroxidase
1.11.1.18
bromide peroxidase
|
–
–
|
|
|
BRENDA:
BS231277
|
|
|
|
3-iodo-L-tyrosine + H2O2 <=> 3-iodo-5-hydroxyl-L-tyrosine + L-Dopa + I-
|
1.11.2.6
L-tyrosine peroxygenase
|
–
|
|
|
BRENDA:
BS455013
|
|
|
|
guaiacol + H2O2 + I- <=> Tetraguaiacol + H2O
|
1.11.1.8
iodide peroxidase
|
–
|
|
|
BRENDA:
BS289006
|
|
|
|
4-Iodobenzoate + H2O <=> 4-hydroxybenzoate + I-
|
3.8.1.6
4-chlorobenzoate dehalogenase
|
–
|
|
|
BRENDA:
BS190240
|
|
|
|
3,3'',5''-triido-L-thyronine + AH <=> 3,3''-diiodothyronine + I- + A + H+
|
1.21.99.3
thyroxine 5-deiodinase
|
–
|
|
|
BRENDA:
BS375763
|
|
|
|
2-iodophenol + NADH + O2 <=> catechol + I- + NAD+
|
1.14.13.1
salicylate 1-monooxygenase
|
–
|
|
|
BRENDA:
BS257940
|
|
|
|
A + I- + H2O2 + H+ <=> RI + 2 H2O
|
1.11.1.B6
|
–
|
|
|
BRENDA:
BR48840
|
|
|
|
I- + H2O2 <=> triiodide
|
1.11.1.B6
|
–
|
|
|
BRENDA:
BS388916
|
|
|
|
3,3'',5-triiodo-L-thyronine_sulfate + reduced_electron_acceptor <=> diiodothyronine + I- + electron_acceptor
|
1.21.99.4
thyroxine 5'-deiodinase
|
–
|
|
|
BRENDA:
BS375766
|
|
|
|
L-thyroxine + electron_acceptor <=> 3,3'',5-triiodothyronine + I- + reduced_electron_acceptor
|
1.21.99.4
thyroxine 5'-deiodinase
|
–
|
|
|
BRENDA:
BS375171
|
|
|
|
glutathione + iodobutane <=> I- + gamma-Glu-L-Cys(S-butyl)-Gly
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388796
|
|
|
|
glutathione + Iodoethane <=> I- + gamma-Glu-L-Cys(S-ethyl)-Gly
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388797
|
|
|
|
glutathione + Propyl_iodide <=> I- + gamma-Glu-L-Cys(S-propyl)-Gly
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388803
|
|
|
|
glutathione + iodohexane <=> I- + S-hexylglutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388799
|
|
|
|
glutathione + iodomethane <=> I- + S-Methylglutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388800
|
|
|
|
glutathione + 1-iodooctane <=> I- + octyl-S-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388801
|
|
|
|
Propyl_iodide + H2O <=> 1-propanol + I-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
|
BRENDA:
BS165592
|
|
|
|
iodomethane + CO + CoA <=> CH3-CO-S-CoA + I-
|
2.3.1.169
CO-methylating acetyl-CoA synthase
|
–
|
|
|
BRENDA:
BS359565
|
|
|
|
1,3-diiodopropane + H2O <=> 3-iodopropanol + I-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
|
BRENDA:
BS371451
|
|
|
|
2-iodobutane + H2O <=> 2-butanol + I-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
|
BRENDA:
BS419910
|
|
|
|
glutathione + 1-iodo-3-phenylpropane <=> I- + 3-phenylpropyl-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388795
|
|
|
|
glutathione + 1-iodoheptane <=> I- + heptyl-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388798
|
|
|
|
glutathione + 1-iodopentane <=> I- + pentyl-glutathione
|
2.5.1.18
glutathione transferase
|
–
|
|
|
BRENDA:
BS388802
|
|
|
|
iodobutane + H2O <=> 1-butanol + I-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
|
BRENDA:
BS165600
|
|
|
|
iodohexane + H2O <=> 1-Hexanol + I-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
|
BRENDA:
BS383571
|
|
|
|
[thyroglobulin]-3-iodo-L-tyrosine + I- + H2O2 <=> [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O
|
1.11.1.8
iodide peroxidase
|
–
|
|
|
BRENDA:
BR50223
|
|
|
|
[thyroglobulin]-L-tyrosine + I- + H2O2 <=> [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O
|
1.11.1.8
iodide peroxidase
|
–
|
|
|
BRENDA:
BR50222
|
|
|
|
1,2,3,3,5-pentamethyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-1,2,3,3,5-pentamethyl-2,3-dihydro-1H-indole + NADP+ + I-
|
1.5.1.48
2-methyl-1-pyrroline reductase
|
–
|
|
|
BRENDA:
BS440471
|
|
|
|
2,3,3-trimethyl-1-propyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-2,3,3-trimethyl-1-propyl-2,3-dihydro-1H-indole + NADP+ + I-
|
1.5.1.48
2-methyl-1-pyrroline reductase
|
–
|
|
|
BRENDA:
BS440569
|
|
|
|
1-ethyl-2,3,3-trimethyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-1-ethyl-2,3,3-trimethyl-2,3-dihydro-1H-indole + NADP+ + I-
|
1.5.1.48
2-methyl-1-pyrroline reductase
|
–
|
|
|
BRENDA:
BS440500
|
|
|
|
1,2,3,3-tetramethyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-1,2,3,3-tetramethyl-2,3-dihydro-1H-indole + NADP+ + I-
|
1.5.1.48
2-methyl-1-pyrroline reductase
|
–
|
|
|
BRENDA:
BS440472
|
|
|
|
5-fluoro-1,2,3,3-tetramethyl-3H-indol-1-ium_iodide + NADPH + H+ <=> (2S)-5-fluoro-1,2,3,3-tetramethyl-2,3-dihydro-1H-indole + NADP+ + I-
|
1.5.1.48
2-methyl-1-pyrroline reductase
|
–
|
|
|
BRENDA:
BS440920
|
|
|
|
1,1,2,3-tetramethyl-1H-benzo[e]indol-3-ium_iodide + NADPH + H+ <=> (-)-1,1,2,3-tetramethyl-2,3-dihydro-1H-benzo[e]indole + NADP+ + I-
|
1.5.1.48
2-methyl-1-pyrroline reductase
|
–
|
|
|
BRENDA:
BS440470
|
|
|
|
4-hydroxybenzoate + 2 NADPH + 2 I- + 2 O2 + 2 H+ <=> 2,4-diiodophenol + 2 NADP+ + CO2 + 4 H2O
|
1.14.19.55
4-hydroxybenzoate brominase (decarboxylating)
|
–
|
|
|
BRENDA:
BS442914
|
|
|
|
triiodophenol + NADPH + O2 <=> Diphenylhydantoin + I- + NADP+ + H2O
|
1.14.13.50
pentachlorophenol monooxygenase
|
–
|
|
|
BRENDA:
BS288311
|
|
|
|
1,3-Dichloropropane + H2O <=> 3-iodopropanol + I-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
|
BRENDA:
BS454780
|
|
|
|
4-iodobenzoyl-CoA + H2O <=> 4-hydroxybenzoyl-CoA + I-
|
3.8.1.7
4-chlorobenzoyl-CoA dehalogenase
|
–
|
|
|
BRENDA:
BS18479
|
|
|
|
Iodoethane + H2O <=> ethanol + I-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
|
BRENDA:
BS453437
|
|
|
|
Biochanin_A + H2O2 + I- <=> 6,8-diiodobiochanin_A + H2O
|
1.11.1.8
iodide peroxidase
|
–
|
|
|
BRENDA:
BS289008
|
|
|
|
thymol_blue + 2 I- + 2 H+ + H2O2 <=> diiodothymol_blue + 2 H2O
|
1.11.1.B6
|
–
|
|
|
BRENDA:
BS442038
|
|
|
|
L-3'',5''-diiodothyronine + reduced_acceptor <=> L-5''-iodothyronine + I- + A + H+
|
1.21.99.3
thyroxine 5-deiodinase
|
–
|
|
|
BRENDA:
BS418736
|
|
|
|
3,3'',5-triiodothyronine + reduced_acceptor <=> diiodothyronine + I- + A + H+
|
1.21.99.4
thyroxine 5'-deiodinase
|
–
|
|
|
BRENDA:
BS356014
|
|
|
|
3,3',5'-triiodothyronine + reduced_acceptor <=> diiodothyronine + I- + A + H+
|
1.21.99.4
thyroxine 5'-deiodinase
|
–
|
|
|
BRENDA:
BS377602
|
|
|
|
L-3,5'',3''-triiodothyronine + reduced_acceptor <=> L-3,3''-diiodothyonine + I- + A + H+
|
1.21.99.4
thyroxine 5'-deiodinase
|
–
|
|
|
BRENDA:
BS418737
|
|
|
|
3,3'',5-triiodo-L-thyronine_sulfate + reduced_acceptor <=> 3,3''-diiodo-L-thyronine_sulfate + I- + A + H+
|
1.21.99.3
thyroxine 5-deiodinase
|
–
|
|
|
BRENDA:
BS359481
|
|
|
|
3-iodothyronine + reduced_acceptor <=> L-thyronine + I- + A + H+
|
1.21.99.3
thyroxine 5-deiodinase
|
–
|
|
|
BRENDA:
BS418274
|
|
|
|
3,5''-diiodo-L-thyronine + reduced_acceptor <=> 3-iodothyronine + I- + A + H+
|
1.21.99.4
thyroxine 5'-deiodinase
|
–
|
|
|
BRENDA:
BS386122
|
|
|
|
tetraiodoethene + reduced_acceptor <=> triiodoethene + I- + acceptor
|
1.21.99.5
tetrachloroethene reductive dehalogenase
|
–
|
|
|
BRENDA:
BS232390
|
|
|
|
Diiodomethane + H2O <=> formaldehyde + I-
|
4.5.1.3
dichloromethane dehalogenase
|
–
|
|
|
BRENDA:
BS363524
|
|
|
|
S-adenosyl-L-methionine + I- <=> 5''-deoxy-5''-iodoadenosine + L-methionine
|
2.5.1.94
adenosyl-chloride synthase
|
–
|
|
|
BRENDA:
BS415293
|
|
|
|
Iodoethane + H2O <=> acetaldehyde + I-
|
4.5.1.3
dichloromethane dehalogenase
|
–
|
|
|
BRENDA:
BS363532
|
|
|
|
iodoacetate + H2O <=> glycolate + I-
|
3.8.1.10
2-haloacid dehalogenase (configuration-inverting)
3.8.1.2
(S)-2-haloacid dehalogenase
3.8.1.3
haloacetate dehalogenase
|
–
–
–
|
|
|
BRENDA:
BS141614
|
|
|
|
iodoacetate + H2O <=> acetate + I- + H+
|
3.8.1.2
(S)-2-haloacid dehalogenase
|
–
|
|
|
BRENDA:
BS419440
|
|
|
|
1,6-diiodohexane + H2O <=> iodohexane + I-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
|
BRENDA:
BS419754
|
|