|
|
H2O + FAD <=> H+ + FMN + AMP
|
3.6.1.18
FAD diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
|
K
|
|
BRENDA:
BR22758
KEGG:
R00160
MetaCyc:
FAD-PYROPHOSPHATASE-RXN
SABIO-RK:
718
|
|
|
|
4-hydroxyphenylacetate + O2 + FADH2 <=> H+ + 3,4-Dihydroxyphenylacetate + H2O + FAD
|
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
|
BM
|
|
BRENDA:
BR40424
MetaCyc:
RXN-8505
|
|
|
|
FAD <=> AMP + riboflavin_cyclic-4,5''-phosphate
|
4.6.1.15
FAD-AMP lyase (cyclizing)
|
–
|
|
|
BRENDA:
BR40593
KEGG:
R07636
MetaCyc:
RXN-11695
|
|
|
|
FMN + ATP + H+ <=> FAD + diphosphate
|
2.7.7.2
FAD synthase
|
–
|
BMK
|
|
BRENDA:
BR47867
KEGG:
R00161
MetaCyc:
FADSYN-RXN
SABIO-RK:
390
|
|
|
|
L-tryptophan + FADH2 + Cl- + O2 <=> 7-chloro-L-tryptophan + FAD + H2O
|
1.14.19.9
tryptophan 7-halogenase
|
–
|
MK
|
|
BRENDA:
BR48866
KEGG:
R09570
MetaCyc:
RXN-10842
SABIO-RK:
14708
|
|
|
|
anthranilate + O2 + FADH2 <=> H+ + 3-Hydroxyanthranilate + H2O + FAD
|
1.14.14.8
anthranilate 3-monooxygenase (FAD)
|
–
|
BMK
|
|
BRENDA:
BR49368
KEGG:
R09517
MetaCyc:
RXN-10724
|
|
|
|
H+ + 15-cis-4,4''-diapophytoene + FAD <=> all-trans-4,4''-diapolycopene + FADH2
|
1.3.8.2
4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)
|
–
|
|
|
BRENDA:
BR49745
KEGG:
R09690
MetaCyc:
RXN-12224
|
|
|
|
15-cis-4,4''-diapophytoene + FAD + H+ <=> all-trans-4,4''-diapophytofluene + FADH2
|
1.3.8.2
4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)
|
–
|
BM
|
|
BRENDA:
BR49746
KEGG:
R09719
MetaCyc:
RXN-9303
|
|
|
|
all-trans-4,4''-diapophytofluene + FAD + H+ <=> all-trans-4,4''-diapo-zeta-carotene + FADH2
|
1.3.8.2
4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)
|
–
|
BM
|
|
BRENDA:
BR49747
KEGG:
R09744
MetaCyc:
RXN-9304
|
|
|
|
all-trans-4,4''-diapo-zeta-carotene + FAD + H+ <=> all-trans-4,4''-diaponeurosporene + FADH2
|
1.3.8
1.3.8.2
4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)
|
–
–
|
BM
|
|
BRENDA:
BR49748
KEGG:
R09745
MetaCyc:
RXN-9305
SABIO-RK:
13047
|
|
|
|
all-trans-4,4''-diaponeurosporene + FAD + H+ <=> all-trans-4,4''-diapolycopene + FADH2
|
1.3.8
1.3.8.2
4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)
|
–
–
|
BMK
|
|
BRENDA:
BR49749
KEGG:
R09746
MetaCyc:
RXN-12258
|
|
|
|
FADH2 + NAD+ <=> FAD + NADH + H+
|
1.14.13.7
phenol 2-monooxygenase (NADPH)
1.18.1.2
ferredoxin---NADP+ reductase
1.18.1.4
rubredoxin---NAD(P)+ reductase
1.3.1.116
7beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase
1.5.1.30
flavin reductase (NADPH)
1.5.1.36
flavin reductase (NADH)
1.5.1.37
FAD reductase (NADH)
1.5.1.41
riboflavin reductase [NAD(P)H]
1.5.1.42
FMN reductase (NADH)
1.5.1.45
FAD reductase [NAD(P)H]
1.6.99.3
NADH dehydrogenase
7.1.1.2
NADH:ubiquinone reductase (H+-translocating)
|
–
–
–
–
–
–
–
–
–
–
–
–
|
K
|
|
BRENDA:
BR49750
KEGG:
R09748
MetaCyc:
RXN-13750_WOP;
RXN-8506
SABIO-RK:
7290
|
|
|
|
Styrene + FADH2 + O2 <=> H+ + (S)-styrene_oxide + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
MK
|
|
BRENDA:
BR49865
KEGG:
R05488
MetaCyc:
RXN-12764
|
|
|
|
trans,octacis-decaprenylphospho-beta-D-ribofuranose + FAD + H+ <=> trans,octacis-decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose + FADH2
|
1.1.98.3
decaprenylphospho-beta-D-ribofuranose 2-dehydrogenase
|
–
|
M
|
|
BRENDA:
BR50145
KEGG:
R10112
MetaCyc:
RXN-11080
|
|
|
|
FADH2 + NADP+ <=> FAD + NADPH + H+
|
1.14.13.7
phenol 2-monooxygenase (NADPH)
1.18.1.2
ferredoxin---NADP+ reductase
1.5.1.30
flavin reductase (NADPH)
1.5.1.36
flavin reductase (NADH)
1.5.1.38
FMN reductase (NADPH)
1.5.1.41
riboflavin reductase [NAD(P)H]
1.5.1.45
FAD reductase [NAD(P)H]
|
–
–
–
–
–
–
–
|
BK
|
|
BRENDA:
BR50246
KEGG:
R09520
MetaCyc:
RXN-13750
SABIO-RK:
7292
|
|
|
|
FAD + [protein]-L-threonine <=> [protein]-FMN-L-threonine + AMP
|
2.7.1.180
FAD:protein FMN transferase
|
–
|
|
|
BRENDA:
BR50805
KEGG:
R10613
MetaCyc:
RXN-14461
|
|
|
|
(S)-3-chloro-beta-tyrosyl-[SgcC2] + FADH2 + O2 <=> (3S)-3-amino-3-(3-chloro-4,5-dihydroxyphenyl)propanoyl-[peptidyl-carrier_protein_SgcC2] + FAD + H2O + H+
|
1.14.14.15
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase
|
–
|
|
|
BRENDA:
BR50846
MetaCyc:
RXN-15398
|
|
|
|
7-chloro-L-tryptophan + FADH2 + Cl- + O2 <=> 6,7-dichloro-L-tryptophan + FAD + H2O
|
1.14.19.60
7-chloro-L-tryptophan 6-halogenase
|
–
|
|
|
BRENDA:
BR51090
KEGG:
R12034
MetaCyc:
RXN-19122
|
|
|
|
L-tryptophan + O2 + Cl- + FADH2 <=> 6-chlorotryptophan + FAD + H2O
|
1.14.19.59
tryptophan 6-halogenase
1.14.19.60
7-chloro-L-tryptophan 6-halogenase
|
–
–
|
|
|
BRENDA:
BR51091
KEGG:
R12032
MetaCyc:
RXN-19121
|
|
|
|
D-tryptophan + O2 + Cl- + FADH2 <=> 6-chloro-D-tryptophan + FAD + H2O
|
1.14.19.59
tryptophan 6-halogenase
|
–
|
|
|
BRENDA:
BR51092
KEGG:
R12033
MetaCyc:
RXN-19634
|
|
|
|
L-tryptophan + O2 + Cl- + FADH2 <=> 5-chloro-L-tryptophan + FAD + H2O
|
1.14.19.58
tryptophan 5-halogenase
|
–
|
|
|
BRENDA:
BR51093
KEGG:
R12031
MetaCyc:
RXN-11104
|
|
|
|
phenol + O2 + FADH2 <=> catechol + H2O + FAD + H+
|
1.14.14.20
phenol 2-monooxygenase (FADH2)
|
–
|
|
|
BRENDA:
BR51578
KEGG:
R11653
MetaCyc:
RXN-17504
|
|
|
|
resorcinol + FADH2 + O2 <=> Hydroxyquinol + FAD + H2O + H+
|
1.14.14.27
resorcinol 4-hydroxylase (FADH2)
|
–
|
MK
|
|
BRENDA:
BR51700
KEGG:
R11348
MetaCyc:
R307-RXN
|
|
|
|
Isobutylamine + O2 + FADH2 <=> N-hydroxy-2-methylpropan-1-amine + H2O + FAD + H+
|
1.14.14.30
isobutylamine N-monooxygenase
|
–
|
|
|
BRENDA:
BR51743
KEGG:
R11403
MetaCyc:
RXN-13669
|
|
|
|
squalene + FAD + H2O + H+ <=> hydroxysqualene + FADH2
|
1.17.8.1
hydroxysqualene dehydroxylase
|
–
|
M
|
|
BRENDA:
BR51747
KEGG:
R11401
MetaCyc:
RXN-17128
|
|
|
|
tetracycline + O2 + Cl- + FADH2 <=> 7-chlorotetracycline + H2O + FAD + H+
|
1.14.19.49
tetracycline 7-halogenase
|
–
|
MK
|
|
BRENDA:
BR51837
KEGG:
R11478
MetaCyc:
RXN-17996
|
|
|
|
3,5,6-trichloro-pyridin-2-ol + FADH2 + O2 <=> 3,6-dichloropyridine-2,5-dione + FAD + Cl- + H2O + H+
|
1.14.14.172
3,5,6-trichloropyridin-2-ol monooxygenase
|
–
|
M
|
|
BRENDA:
BR53067
KEGG:
R12617
MetaCyc:
RXN-20730
|
|
|
|
3,6-dichloropyridine-2,5-diol + FADH2 + O2 <=> 6-chloro-3-hydroxypyridine-2,5-dione + FAD + Cl- + H2O + H+
|
1.14.14.172
3,5,6-trichloropyridin-2-ol monooxygenase
|
–
|
M
|
|
BRENDA:
BR53068
KEGG:
R12618
MetaCyc:
RXN-20727
|
|
|
|
6-chloropyridine-2,3,5-triol + FADH2 + O2 <=> 3,6-dihydroxypyridine-2,5-dione + FAD + Cl- + H2O + H+
|
1.14.14.172
3,5,6-trichloropyridin-2-ol monooxygenase
|
–
|
M
|
|
BRENDA:
BR53069
KEGG:
R12619
MetaCyc:
RXN-20729
|
|
|
|
2,4,6-Trichlorophenol + O2 + FADH2 <=> 2,6-dichloroquinone + Cl- + H2O + FAD + H+
|
1.14.14.173
2,4,6-trichlorophenol monooxygenase
|
–
|
MK
|
|
BRENDA:
BR53070
KEGG:
R05449
MetaCyc:
RXN-20721
|
|
|
|
2,6-dichlorohydroquinone + O2 + FADH2 <=> 2-chloro-6-hydroxy-1,4-benzoquinone + H2O + Cl- + FAD + H+
|
1.14.14.173
2,4,6-trichlorophenol monooxygenase
|
–
|
M
|
|
BRENDA:
BR53071
KEGG:
R12627
MetaCyc:
RXN-20723
|
|
|
|
D-gluconate + FAD + H+ <=> 2-dehydro-D-gluconate + FADH2
|
1.1.99.3
gluconate 2-dehydrogenase (acceptor)
|
–
|
BK
|
|
BRENDA:
BS370913
KEGG:
R01741
MetaCyc:
RXN-14204
|
|
|
|
N6-(2-isopentenyl)adenine + FAD + H2O + H+ <=> 3-methylbut-2-enal + adenine + FADH2
|
1.5.99
1.5.99.12
cytokinin dehydrogenase
|
–
–
|
M
|
|
BRENDA:
BS371066
MetaCyc:
RXN-4621
|
|
|
|
N6-isopentenyladenosine + H2O + FAD + H+ <=> adenosine + 3-methylbut-2-enal + FADH2
|
1.5.99
1.5.99.12
cytokinin dehydrogenase
|
–
–
|
M
|
|
BRENDA:
BS371069
MetaCyc:
RXN-4641
|
|
|
|
L-proline + FAD <=> L-pyrroline-5-carboxylate + FADH2
|
1.5
1.5.5.2
proline dehydrogenase
1.5.8
1.5.99.B2
|
–
–
–
–
|
BK
|
|
BRENDA:
BS389060
KEGG:
R10507
MetaCyc:
RXN-21556
|
|
|
|
trans-zeatin + H2O + FAD + H+ <=> adenine + 4-hydroxy-3-methylbut-2-enal + FADH2
|
1.5.99
1.5.99.12
cytokinin dehydrogenase
|
–
–
|
M
|
|
BRENDA:
BS413661
MetaCyc:
RXN-4661
|
|
|
|
15-cis-4,4''-diapophytoene + FAD + H+ <=> all-trans-4,4''-diaponeurosporene + FADH2
|
1.3.8.2
4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)
1.3.8.o
|
–
–
|
K
|
|
BRENDA:
BS415533
KEGG:
R07653
MetaCyc:
RXN-15614
|
|
|
|
p-coumaric_acid + O2 + FADH2 <=> caffeic_acid + H2O + FAD + H+
|
1.14.14
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
–
|
M
|
|
BRENDA:
BS428032
MetaCyc:
RXN-14988
|
|
|
|
L-tyrosine + O2 + FADH2 <=> L-Dopa + H2O + FAD + H+
|
1.14.14
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
–
|
M
|
|
BRENDA:
BS428763
MetaCyc:
RXN-14990
|
|
|
|
5,10-methylenetetrahydrofolate + tRNA_UpsiC + FADH2 <=> tetrahydrofolate + tRNA_TpsiC + FAD
|
2.1.1.74
methylenetetrahydrofolate---tRNA-(uracil54-C5)-methyltransferase [NAD(P)H-oxidizing]
|
–
|
|
|
BRENDA:
BS319868
KEGG:
R03704
|
|
|
|
glutaryl-CoA + FAD <=> crotonyl-CoA + CO2 + FADH2
|
1.3.8.6
glutaryl-CoA dehydrogenase (ETF)
|
–
|
K
|
|
BRENDA:
BS413390
KEGG:
R02487
SABIO-RK:
2417
|
|
|
|
succinate + FAD <=> fumarate + FADH2
|
1.3.1.6
fumarate reductase (NADH)
1.3.5.1
succinate dehydrogenase
|
–
–
|
B
|
|
BRENDA:
BS413615
KEGG:
R00408
SABIO-RK:
865
|
|
|
|
butyryl-CoA + FAD <=> crotonyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
|
K
|
|
BRENDA:
BS414397
KEGG:
R01175
SABIO-RK:
1412
|
|
|
|
hexanoyl-CoA + FAD <=> trans-2-hexenoyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
–
|
K
|
|
BRENDA:
BS414702
KEGG:
R04751
SABIO-RK:
4407
|
|
|
|
isovaleryl-CoA + FAD <=> 3-methylcrotonoyl-CoA + FADH2
|
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
–
|
BK
|
|
BRENDA:
BS424839
KEGG:
R04095
SABIO-RK:
3822
|
|
|
|
2,4,5-Trichlorophenol + O2 + FADH2 <=> 2,5-dichlorohydroquinone + Cl- + H2O + FAD + H+
|
1.14.14
|
–
|
MK
|
|
KEGG:
R05447
MetaCyc:
RXN-10134
|
|
|
|
2,5-dichloro-p-quinol + O2 + FADH2 <=> 5-chloro-2-hydroxy-[1,4]-benzoquinone + Cl- + H2O + FAD + H+
|
1.14.14
|
–
|
MK
|
|
KEGG:
R05446
MetaCyc:
RXN-10135
|
|
|
|
4-(2-amino-3-chlorophenyl)pyrrole + Cl- + O2 + FADH2 <=> aminopyrrolnitrin + H2O + FAD
|
1.14.19
|
–
|
MK
|
|
KEGG:
R11106
MetaCyc:
RXN-11793
|
|
|
|
2-hydroxyglutarate + FAD + H+ <=> 2-oxoglutarate + FADH2
|
1.1.99.2
L-2-hydroxyglutarate dehydrogenase
|
–
|
K
|
|
KEGG:
R03534
MetaCyc:
RXN-14103
|
|
|
|
palmitoyl-CoA + FAD <=> trans-2-hexadecenoyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.8.9
very-long-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
|
K
|
|
KEGG:
R01279
SABIO-RK:
1495
|
|
|
|
octanoyl-CoA + FAD <=> 2-octenoyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
|
K
|
|
KEGG:
R03777
SABIO-RK:
3536
|
|
|
|
lauroyl-CoA + FAD <=> trans-2-dodecenoyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
|
K
|
|
KEGG:
R03857
SABIO-RK:
3607
|
|
|
|
myristoyl-CoA + FAD <=> 2-tetradecenoyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.8.9
very-long-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
|
K
|
|
KEGG:
R03990
SABIO-RK:
3725
|
|
|
|
decanoyl-CoA + FAD <=> trans-2-decenoyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
|
K
|
|
KEGG:
R04754
SABIO-RK:
4410
|
|
|
|
sucrose + FAD <=> 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + FADH2
|
1.1.99.13
glucoside 3-dehydrogenase
|
–
|
K
|
|
KEGG:
R00807
|
|
|
|
sn-glycerol_3-phosphate + FAD <=> dihydroxyacetone_phosphate + FADH2
|
1.1.5.3
glycerol-3-phosphate dehydrogenase
|
–
|
K
|
|
KEGG:
R00848
|
|
|
|
(S)-malate + FAD <=> oxaloacetate + FADH2
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
K
|
|
KEGG:
R01257
|
|
|
|
L-pipecolic_acid + FAD <=> FADH2 + (S)-2,3,4,5-tetrahydropyridine-2-carboxylate
|
1.5.99.3
L-pipecolate dehydrogenase
|
–
|
K
|
|
KEGG:
R02205
|
|
|
|
D-sorbitol + FAD <=> FADH2 + L-sorbose
|
1.1.99.21
D-sorbitol dehydrogenase (acceptor)
|
–
|
K
|
|
KEGG:
R02925
|
|
|
|
sphinganine + FAD <=> FADH2 + sphingosine
|
1.3.99
|
–
|
|
|
KEGG:
R02979
|
|
|
|
chenodeoxycholic_acid + FADH2 <=> lithocholic_acid + FAD + H2O
|
not assigned
|
–
|
|
|
KEGG:
R03978
|
|
|
|
3-dehydrosphinganine + FAD <=> 3-Ketosphingosine + FADH2
|
not assigned
|
–
|
|
|
KEGG:
R04092
|
|
|
|
3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA + FAD <=> (24E)-3alpha,7alpha-dihydroxy-5beta-cholest-24-enoyl-CoA + FADH2
|
1.3.99
|
–
|
|
|
KEGG:
R04547
|
|
|
|
trihydroxycoprostanoyl-CoA + FAD <=> (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + FADH2
|
1.3.99
|
–
|
|
|
KEGG:
R04592
|
|
|
|
4-de(dimethylamino)-4-oxoanhydrotetracycline + FADH2 + Cl- + O2 + H+ <=> 4-Ketoanhydrochlortetracycline + FAD + 2 H2O
|
1.14.14
|
–
|
|
|
KEGG:
R05456
|
|
|
|
melilotate + ATP + CoA + FAD + NAD+ <=> salicylate + AMP + diphosphate + FADH2 + acetyl-CoA + NADH + H+
|
not assigned
|
–
|
K
|
|
KEGG:
R05537
|
|
|
|
sucrose + FAD <=> 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + FADH2
|
1.1.99.13
glucoside 3-dehydrogenase
|
–
|
|
|
KEGG:
R06233
|
|
|
|
2-naphthoic_acid + FADH2 + O2 <=> 1-hydroxy-2-naphthoate + FAD + H2O
|
not assigned
|
–
|
K
|
|
KEGG:
R06902
|
|
|
|
adipyl-CoA + FAD <=> 2,3-dehydroadipyl-CoA + FADH2
|
1.3.99
|
–
|
K
|
|
KEGG:
R06943
|
|
|
|
deoxycholate + FAD + H2O <=> cholic_acid + FADH2
|
not assigned
|
–
|
|
|
KEGG:
R07220
|
|
|
|
OPC8-CoA + FAD <=> trans-2-Enoyl-OPC8-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
K
|
|
KEGG:
R07888
|
|
|
|
OPC6-CoA + FAD <=> trans-2-Enoyl-OPC6-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
K
|
|
KEGG:
R07892
|
|
|
|
OPC4-CoA + FAD <=> trans-2-Enoyl-OPC4-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
K
|
|
KEGG:
R07896
|
|
|
|
5-methylhex-4-enoyl-CoA + FAD <=> (2E)-5-methylhexa-2,4-dienoyl-CoA + FADH2
|
1.3.99
|
–
|
K
|
|
KEGG:
R08092
|
|
|
|
AMP + sulfite + FAD <=> adenosine_5'-phosphosulfate + FADH2
|
1.8.99.2
adenylyl-sulfate reductase
|
–
|
K
|
|
KEGG:
R08553
|
|
|
|
(S)-3-Chloro-beta-tyrosyl-[pcp] + FADH2 + O2 <=> (S)-3-Chloro-4,5-dihydroxy-beta-phenylalanyl-[pcp] + FAD + H2O
|
1.14.14.15
(3S)-3-amino-3-(3-chloro-4-hydroxyphenyl)propanoyl-[peptidyl-carrier protein SgcC2] monooxygenase
|
–
|
K
|
|
KEGG:
R10731
|
|
|
|
3-methylthiopropionyl-CoA + FAD <=> 3-(methylthio)acryloyl-CoA + FADH2
|
1.3.8
|
–
|
K
|
|
KEGG:
R11130
|
|
|
|
gentamicin_X2 + FAD <=> 6''-Oxogentamicin_X2 + FADH2
|
not assigned
|
–
|
K
|
|
KEGG:
R11295
|
|
|
|
geneticin + FAD <=> 6''-Oxo-G418 + FADH2
|
not assigned
|
–
|
K
|
|
KEGG:
R11296
|
|
|
|
(S)-beta-Tyrosyl-[pcp] + FADH2 + Cl- + O2 + H+ <=> (S)-3-Chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
|
1.14.19
|
–
|
K
|
|
KEGG:
R11368
|
|
|
|
(R)-2-Aza-beta-tyrosyl-[pcp] + FADH2 + Cl- + O2 + H+ <=> (R)-2-Aza-3-chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
|
1.14.19
|
–
|
K
|
|
KEGG:
R11393
|
|
|
|
2-Methyl-3-n-amyl-dihydropyrrole + FAD <=> 2-Methyl-3-n-amyl-pyrrole + FADH2
|
not assigned
|
–
|
K
|
|
KEGG:
R11661
|
|
|
|
(1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] + FADH2 + Cl- + O2 <=> 5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + FAD + 2 H2O
|
1.14.19.56
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase
|
–
|
|
|
KEGG:
R12021
|
|
|
|
5-Chloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + FADH2 + Cl- + O2 <=> 4,5-Dichloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + FAD + 2 H2O
|
1.14.19.56
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase
|
–
|
|
|
KEGG:
R12022
|
|
|
|
(1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] + 2 FADH2 + 2 Cl- + 2 O2 <=> 4,5-Dichloro-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + 2 FAD + 4 H2O
|
1.14.19.56
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase
|
–
|
|
|
KEGG:
R12023
|
|
|
|
(1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] + FADH2 + Br- + O2 <=> 5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + FAD + 2 H2O
|
1.14.19.57
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase
|
–
|
|
|
KEGG:
R12027
|
|
|
|
5-Bromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + FADH2 + Br- + O2 <=> 4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + FAD + 2 H2O
|
1.14.19.57
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase
|
–
|
|
|
KEGG:
R12028
|
|
|
|
4,5-Dibromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + FADH2 + Br- + O2 <=> 3,4,5-Tribromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + FAD + 2 H2O
|
1.14.19.57
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase
|
–
|
|
|
KEGG:
R12029
|
|
|
|
(1H-pyrrole-2-carbonyl)-[peptidyl-carrier_protein] + 3 FADH2 + 3 Br- + 3 O2 <=> 3,4,5-Tribromo-1H-pyrrole-2-carbonyl-[peptidyl-carrier_protein] + 3 FAD + 6 H2O
|
1.14.19.57
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase
|
–
|
|
|
KEGG:
R12030
|
|
|
|
FAD + H+ + e- <=> FADH2
|
not assigned
|
–
|
|
|
MetaCyc:
REDUCEDFAD-RXN
|
|
|
|
H+ + 2,5-dichloro-p-quinol + FAD <=> 2,5-dichlorohydroquinone + FADH2
|
1.3.8
|
–
|
M
|
|
MetaCyc:
RXN-12312
|
|
|
|
5-chloro-1,2,4-trihydroxybenzene + FAD <=> 5-chloro-2-hydroxy-[1,4]-benzoquinone + FADH2
|
1.3.8
|
–
|
M
|
|
MetaCyc:
RXN-12313
|
|
|
|
sulochrin + Cl- + O2 + FADH2 <=> dihydrogeodin + H2O + FAD
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-13552
|
|
|
|
decanoyl-HmqF_protein + FAD + H+ <=> 2,3-dehydro-decanoyl-HmqF + FADH2
|
1.3.8
|
–
|
|
|
MetaCyc:
RXN-13624
|
|
|
|
spinosyn_macrolactone + FAD + H+ <=> 15-oxo_spinosyn_macrolactone + FADH2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-13626
|
|
|
|
8-demethylnovobiocic_acid + Cl- + FADH2 + O2 <=> Chlorobiocate + FAD + H2O
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-14684
|
|
|
|
4-(2-hydroxyethyl)phenol + O2 + FADH2 <=> 3,4-dihydroxyphenylethanol + H2O + FAD + H+
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-14989
|
|
|
|
(S)-beta-tyrosyl-[SgcC2] + Cl- + O2 + FADH2 <=> (S)-3-chloro-beta-tyrosyl-[SgcC2] + H2O + FAD
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-15397
|
|
|
|
griseophenone_C + Cl- + FADH2 + O2 <=> griseophenone_B + FAD + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-16536
|
|
|
|
2-aminomalonyl_semialdehyde-[L-seryl-carrier_protein] + H2O + FAD <=> aminomalonyl-[L-seryl-carrier_protein] + FADH2
|
1.2.98
|
–
|
M
|
|
MetaCyc:
RXN-16908
|
|
|
|
(2R)-2-hydroxy-3-oxopropanoyl-[acp] + FAD + H2O <=> (2R)-2-hydroxymalonyl-[acp] + FADH2
|
1.2.98
|
–
|
M
|
|
MetaCyc:
RXN-16916
|
|
|
|
1''-carboxy-chondrochloren_A + FAD + H+ <=> chondrochloren_A + CO2 + FADH2
|
4.1.1.M3
|
–
|
|
|
MetaCyc:
RXN-17063
|
|
|
|
1''-carboxy-chondrochloren_B + FAD + H+ <=> chondrochloren_B + CO2 + FADH2
|
4.1.1.M3
|
–
|
|
|
MetaCyc:
RXN-17064
|
|
|
|
(R)-beta-hydroxy-L-kynurenine + H2O + FAD <=> (2S,3R)-2-[(2-aminophenyl)amino]-3-carboxy-3-hydroxypropanoate + FADH2 + H+
|
2.6.99
|
–
|
M
|
|
MetaCyc:
RXN-17144
|
|
|
|
(1S,2Z)-5-amino-1-(3-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}oxiran-2-yl)pent-2-en-1-ol + FAD <=> 2-(3-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}oxiran-2-yl)-5,6-dihydro-1H-pyridin-2-ol + FADH2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18634
|
|
|
|
(1E,3S,4Z)-7-amino-1-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}hepta-1,4-dien-3-ol + O2 + FADH2 <=> (1S,2Z)-5-amino-1-(3-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}oxiran-2-yl)pent-2-en-1-ol + H2O + FAD + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18635
|
|
|
|
(3Z,5S,6E,8E,10E)-1-aminododeca-3,6,8,10-tetraen-5-ol + O2 + FADH2 <=> (1E,3S,4Z)-7-amino-1-{3-[(1E)-prop-1-en-1-yl]oxiran-2-yl}hepta-1,4-dien-3-ol + H2O + FAD + H+
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-18636
|
|
|
|
melleolide_F + Cl- + FADH2 + O2 <=> 6''-chloromelleolide_F + FAD + H2O
|
1.14.19
|
–
|
M
|
|
MetaCyc:
RXN-18831
|
|
|
|
1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + Cl- + O2 + FADH2 <=> 4,5-dichloro-1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + H2O + FAD
|
1.14.19.56
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] chlorinase
|
–
|
|
|
MetaCyc:
RXN-19067
|
|
|
|
1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + Br- + O2 + FADH2 <=> 3,4,5-tribromo-1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + H2O + FAD
|
1.14.19.57
1H-pyrrole-2-carbonyl-[peptidyl-carrier protein] brominase
|
–
|
|
|
MetaCyc:
RXN-19072
|
|
|
|
1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + Cl- + O2 + FADH2 <=> 5-chloro-1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + H2O + FAD
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19081
|
|
|
|
5-chloro-1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + Cl- + O2 + FADH2 <=> 4,5-dichloro-1H-pyrrole-2-carbonyl-[PltL_prolyl-carrier_protein] + H2O + FAD
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19082
|
|
|
|
1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + Br- + O2 + FADH2 <=> 5-bromo-1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + H2O + FAD
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19094
|
|
|
|
5-bromo-1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + Br- + O2 + FADH2 <=> 4,5-dibromo-1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + H2O + FAD
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19095
|
|
|
|
4,5-dibromo-1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + Br- + O2 + FADH2 <=> 3,4,5-tribromo-1H-pyrrole-2-carbonyl-[Bmp1_prolyl-carrier_protein] + H2O + FAD
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-19096
|
|
|
|
7-hydroxy-3-isocyanochromen-2-one + O2 + FADH2 <=> paerucumarin + H2O + FAD + H+
|
1.14.14
|
–
|
|
|
MetaCyc:
RXN-19267
|
|
|
|
tricarballylate + FAD + H+ <=> cis-aconitate + FADH2
|
1.3.8.M1
|
–
|
|
|
MetaCyc:
RXN-20071
|
|
|
|
FADH2 + electron-transfer_quinone <=> FAD + electron-transfer_quinol + H+
|
not assigned
|
–
|
|
|
MetaCyc:
RXN-20072
|
|
|
|
naphthomycin_E + FADH2 + Cl- + O2 <=> naphthomycin_A + FAD + H2O
|
1.14.19.M25
|
–
|
M
|
|
MetaCyc:
RXN-20303
|
|
|
|
FAD + protein-L-histidine + H+ <=> [protein]-L-histidine-FADH2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20704
|
|
|
|
2,6-dichlorohydroquinone + FAD + H+ <=> 2,6-dichloroquinone + FADH2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20722
|
|
|
|
6-chlorohydroxyquinol + FAD + H+ <=> 2-chloro-6-hydroxy-1,4-benzoquinone + FADH2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20724
|
|
|
|
3,6-dichloropyridine-2,5-diol + FAD + H+ <=> 3,6-dichloropyridine-2,5-dione + FADH2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-20726
|
|
|
|
L-3-oxoalanyl-[L-seryl-carrier_protein] + H2O + FAD <=> aminomalonyl-[L-seryl-carrier_protein] + FADH2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-21124
|
|
|
|
cis-zeatin + H2O + FAD + H+ <=> (2Z)-4-hydroxy-3-methylbut-2-enal + adenine + FADH2
|
1.5.99
|
–
|
M
|
|
MetaCyc:
RXN-4662
|
|
|
|
zeatin_riboside + H2O + FAD + H+ <=> adenosine + 4-hydroxy-3-methylbut-2-enal + FADH2
|
1.5.99
|
–
|
M
|
|
MetaCyc:
RXN-4681
|
|
|
|
5-carboxymethylaminomethyl-2-thiouridine34_in_tRNA + H2O + FAD + H+ <=> 5-aminomethyl-2-thiouridine34_in_tRNA + glyoxylate + FADH2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN0-7081
|
|
|
|
FAD <=> FAD
|
not assigned
|
–
|
|
|
MetaCyc:
TRANS-RXN-272
|
|
|
|
2-Vinylpyridine + FADH2 + O2 <=> 2-(oxiran-2-yl)pyridine + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416130
|
|
|
|
4-Vinylpyridine + FADH2 + O2 <=> 4-(oxiran-2-yl)pyridine + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416302
|
|
|
|
cinnamyl_alcohol + FADH2 + O2 <=> (3-phenyloxiran-2-yl)methanol + 1-phenylpropane-1,2,3-triol + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS415823
|
|
|
|
cinnamyl_acetate + FADH2 + O2 <=> (3-phenyloxiran-2-yl)methyl_acetate + 2,3-dihydroxy-3-phenylpropyl_acetate + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS415824
|
|
|
|
methyl_cinnamate + FADH2 + O2 <=> methyl_3-phenyloxirane-2-carboxylate + methyl_2,3-dihydroxy-3-phenylpropanoate + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS417259
|
|
|
|
3-chlorostyrene + FADH2 + O2 <=> (2S)-2-(3-chlorophenyl)oxirane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416225
|
|
|
|
3-methylstyrene + FADH2 + O2 <=> (2S)-2-(3-methylphenyl)oxirane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416243
|
|
|
|
4-fluorostyrene + FADH2 + O2 <=> (2S)-2-(4-fluorophenyl)oxirane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416307
|
|
|
|
Indene + FADH2 + O2 <=> (1aS,6aR)-6,6a-dihydro-1aH-indeno[1,2-b]oxirene + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416077
|
|
|
|
(+)-5-oxo-1,2-campholide + FAD + H2O <=> (+)-bornane-2,5-dione + FADH2 + O2
|
1.14.14.108
2,5-diketocamphane 1,2-monooxygenase
|
–
|
|
|
BRENDA:
BS451298
|
|
|
|
2-methylstyrene + FADH2 + O2 <=> (S)-2-methyl-2-phenyloxirane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416147
|
|
|
|
6-chlorotryptophan + FADH2 + Cl- + O2 + H+ <=> 6,7-dichloro-L-tryptophan + FAD + 2 H2O
|
1.14.19.9
tryptophan 7-halogenase
|
–
|
|
|
BRENDA:
BS442221
|
|
|
|
2-chlorostyrene + FADH2 + O2 <=> (2S)-2-(2-chlorophenyl)oxirane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416124
|
|
|
|
2-ethylstyrene + FADH2 + O2 <=> (S)-2-ethyl-2-phenyloxirane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS416132
|
|
|
|
4-hydroxyphenylpropionic_acid + FADH2 + O2 <=> 3,4-Dihydroxyphenylpropionate + FAD + H2O
|
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
|
|
|
BRENDA:
BS442839
|
|
|
|
asperlicin_C + FADH2 + O2 <=> asperlicin_E + FAD + H2O
|
1.14.13.216
asperlicin C monooxygenase
|
–
|
|
|
BRENDA:
BS434614
|
|
|
|
dibenzothiophene + 2 FADH2 + 2 O2 <=> dibenzothiophene-5,5-dioxide + 2 FAD + 2 H2O
|
1.14.14.21
dibenzothiophene monooxygenase
|
–
|
|
|
BRENDA:
BS435450
|
|
|
|
tryptamine + FADH2 + Cl- + O2 + H+ <=> 7-chloro-L-tryptamine + FAD + H2O
|
1.14.19.9
tryptophan 7-halogenase
|
–
|
|
|
BRENDA:
BS428980
|
|
|
|
benzothiophene + FADH2 + O2 <=> benzo[b]thiophene_sulfoxide + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS428433
|
|
|
|
indole + FADH2 + O2 <=> indole_2,3-oxide + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS428707
|
|
|
|
(4S)-tetracycline + FADH2 + Cl- + O2 + H+ <=> 7-chloro-(4S)-tetracycline + FAD + 2 H2O
|
1.14.19.49
tetracycline 7-halogenase
|
–
|
|
|
BRENDA:
BS436219
|
|
|
|
L-kynurenine + FADH2 + Cl- + O2 + H+ <=> 5-chloro-L-kynurenine + FAD + 2 H2O
|
1.14.19.59
tryptophan 6-halogenase
|
–
|
|
|
BRENDA:
BS443670
|
|
|
|
2-chlorophenol + FADH2 + O2 <=> 3-chlorocatechol + FAD + H2O
|
1.14.14.20
phenol 2-monooxygenase (FADH2)
|
–
|
|
|
BRENDA:
BS434517
|
|
|
|
7-methoxyindole + FADH2 + O2 <=> 7-methoxy-1,2-dihydro-3H-indol-3-one + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442990
|
|
|
|
N-methylindole + FADH2 + O2 <=> 1-methyl-1,2-dihydro-3H-indol-3-one + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442707
|
|
|
|
4-methoxyindole + FADH2 + O2 <=> 4-methoxy-1,2-dihydro-3H-indol-3-one + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442920
|
|
|
|
5-methoxyindole + FADH2 + O2 <=> 5-methoxy-1,2-dihydro-3H-indol-3-one + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442971
|
|
|
|
6-methoxyindole + FADH2 + O2 <=> 6-methoxy-1,2-dihydro-3H-indol-3-one + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442982
|
|
|
|
1-methylindole-5-carboxylate + FADH2 + O2 <=> 1-methyl-3-oxo-2,3-dihydro-1H-indole-5-carboxylic_acid + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442708
|
|
|
|
6-chloroindole + FADH2 + O2 <=> 6-chloro-1,2-dihydro-3H-indol-3-one + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442980
|
|
|
|
6-bromoindole + FADH2 + O2 <=> 6-bromo-1,2-dihydro-3H-indol-3-one + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442978
|
|
|
|
7-azaindole + FADH2 + O2 <=> 1,2-dihydro-3H-pyrrolo[2,3-b]pyridin-3-one + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442986
|
|
|
|
6-chlorohex-1-ene + FADH2 + O2 <=> (S)-1,2-epoxy-6-chlorohexane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442979
|
|
|
|
6-bromohex-1-ene + FADH2 + O2 <=> (S)-1,2-epoxy-6-bromohexane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS442977
|
|
|
|
hept-1-ene + FADH2 + O2 <=> (S)-1,2-epoxy-2-methylhexane + FAD + H2O
|
1.14.14.11
styrene monooxygenase
|
–
|
|
|
BRENDA:
BS443625
|
|
|
|
2-methylhex-1-ene + FADH2 + O2 <=> (S)-1,2-epoxy-2-methylhexane |