|
|
pyrimidodiazepine + GSSG + H2O <=> 6-pyruvoyltetrahydropterin + glutathione
|
1.5.4.1
pyrimidodiazepine synthase
|
–
|
MK
|
| |
BRENDA:
BR40353
KEGG:
R03984
MetaCyc:
1.5.4.1-RXN
|
|
|
|
7,8-dihydroneopterin_3''-triphosphate <=> 6-pyruvoyltetrahydropterin + tripolyphosphate + H+
|
4.2.3.12
6-pyruvoyltetrahydropterin synthase
|
–
|
BMK
|
| |
BRENDA:
BR48350
KEGG:
R04286
MetaCyc:
4.2.3.12-RXN
SABIO-RK:
9435
|
|
|
|
tetrahydrobiopterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
|
–
|
K
|
| |
BRENDA:
BR50007
KEGG:
R08208
MetaCyc:
RXN-8853
|
|
|
|
L-threo-(6R,1'S,2'S)-5,6,7,8-tetrahydrobiopterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325
sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
|
–
–
|
|
| |
BRENDA:
BS383041
MetaCyc:
RXN-13030
|
|
|
|
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.21
aldose reductase
1.1.1.220
6-pyruvoyltetrahydropterin 2'-reductase
|
–
–
–
–
|
K
|
| |
BRENDA:
BR29261
KEGG:
R04285
|
|
|
|
L-threo-tetrahydrobiopterin + 2 NADP+ <=> 6-pyruvoyltetrahydropterin + 2 NADPH + 2 H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325
sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
|
–
–
|
K
|
| |
BRENDA:
BR50020
KEGG:
R09990
|
|
|
|
6-(1''-Hydroxy-2''-oxopropyl)-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
|
–
–
|
K
|
| |
KEGG:
R11763
|
|
|
|
(6R)-6-lactoyl-5,6,7,8-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+
|
1.1.1.220
6-pyruvoyltetrahydropterin 2'-reductase
|
–
|
M
|
| |
MetaCyc:
1.1.1.220-RXN
|
|
|
|
6-pyruvoyltetrahydropterin <=> pterin
|
not assigned
|
–
|
M
|
| |
MetaCyc:
RXN-15260
|
|
|
|
6-(L-erythro-1,2-dihydroxypropyl_3-monophosphate)-7,8-dihydropterin <=> 6-pyruvoyltetrahydropterin + phosphate
|
4.2.3.12
6-pyruvoyltetrahydropterin synthase
|
–
|
|
| |
BRENDA:
BS363427
|
|
|
|
6-pyruvoyltetrahydropterin + glutathione <=> pyrimidodiazepine
|
1.5.4.1
pyrimidodiazepine synthase
|
–
|
|
| |
BRENDA:
BS287683
|
|
|
|
6-pyruvoyltetrahydropterin + 3 NADPH + 3 H+ <=> L-threo-7,8-dihydrobiopterin + 3 NADP+
|
1.1.1.325
sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
|
–
|
|
| |
BRENDA:
BS417871
|
|
|
|
2''-3H-dihydroneopterin_triphosphate <=> 6-pyruvoyltetrahydropterin + tripolyphosphate
|
4.2.3.12
6-pyruvoyltetrahydropterin synthase
|
–
|
|
| |
BRENDA:
BS363429
|
|
|
|
6-pyruvoyltetrahydropterin + H2O <=> 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + tripolyphosphate
|
4.1.2.50
6-carboxytetrahydropterin synthase
|
–
|
|
| |
BRENDA:
BS418339
|
|
