|
|
6-hydroxymethyl-7,8-dihydropterin_diphosphate + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + diphosphate
|
2.5.1.15
dihydropteroate synthase
|
–
|
MK
|
| |
BRENDA:
BR47663
KEGG:
R03067
MetaCyc:
H2PTEROATESYNTH-RXN
SABIO-RK:
2910
|
|
|
|
2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP <=> H+ + 6-hydroxymethyl-7,8-dihydropterin_diphosphate + AMP
|
2.7.6.3
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
|
–
|
BMK
|
| |
BRENDA:
BR47856
KEGG:
R03503
MetaCyc:
H2PTERIDINEPYROPHOSPHOKIN-RXN
SABIO-RK:
3292
|
|
|
|
4-(beta-D-ribofuranosyl)aminobenzene-5''-phosphate + 6-hydroxymethyl-7,8-dihydropterin_diphosphate <=> 7,8-dihydropterin-6-ylmethyl-4-(beta-D-ribofuranosyl)aminobenzene_5''-phosphate + diphosphate
|
2.5.1.105
7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
|
–
|
K
|
| |
BRENDA:
BR50431
KEGG:
R10339
MetaCyc:
RXN-10009
|
|
|
|
6-hydroxymethyl-7,8-dihydropterin_diphosphate + 4-aminobenzoyl_glutamic_acid <=> diphosphate + 7,8-dihydrofolate
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS356230
SABIO-RK:
9563
|
|
|
|
6-hydroxymethyl-7,8-dihydropterin_diphosphate + sulfamethoxazole <=> diphosphate + dihydropterin-sulfamethoxazole
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS356232
|
|
|
|
Sulfadiazine + 6-hydroxymethyl-7,8-dihydropterin_diphosphate <=> diphosphate + 4-[[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino]-N-pyrimidin-2-ylbenzenesulfonamide
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS401977
|
|
|
|
6-hydroxymethyl-7,8-dihydropterin_diphosphate + sulfathiazole <=> diphosphate + dihydropterin-sulfathiazole
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS356231
|
|
|
|
sulfathiazole + 6-hydroxymethyl-7,8-dihydropterin_diphosphate <=> diphosphate + 4-[[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino]-N-1,3-thiazol-2-ylbenzenesulfonamide
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS401981
|
|
|
|
6-hydroxymethyl-7,8-dihydropterin_diphosphate + 1-(4-aminophenyl)-1-deoxy-D-ribitol <=> 7,8-dihydropterin-6-methyl-1-(4-aminophenyl)-1-deoxy-D-ribitol + diphosphate
|
2.5.1.105
7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
|
–
|
|
| |
BRENDA:
BS420140
|
|
|
|
sulfamethazole + 6-hydroxymethyl-7,8-dihydropterin_diphosphate <=> diphosphate + 4-[[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino]-N-(5-methyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS401978
|
|
|
|
2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + MgATP2- <=> 6-hydroxymethyl-7,8-dihydropterin_diphosphate + MgAMP
|
2.7.6.3
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
|
–
|
|
| |
BRENDA:
BS386165
|
|
|
|
dATP + 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine <=> dAMP + 6-hydroxymethyl-7,8-dihydropterin_diphosphate
|
2.7.6.3
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
|
–
|
|
| |
BRENDA:
BS358315
|
|
|
|
6-hydroxymethyl-7,8-dihydropterin_diphosphate + sulfanilamide <=> diphosphate + dihydropterin-sulfanilamide
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS356233
|
|
|
|
sulfanilamide + 6-hydroxymethyl-7,8-dihydropterin_diphosphate <=> diphosphate + 4-[[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino]benzenesulfonamide
|
2.5.1.15
dihydropteroate synthase
|
–
|
|
| |
BRENDA:
BS401980
|
|
