|
|
pyruvate + D-methionine <=> L-alanine + 4-methylsulfanyl-2-oxobutanoate
|
2.6.1.21
D-amino-acid transaminase
2.6.1.41
D-methionine---pyruvate transaminase
|
–
–
|
B
|
|
BRENDA:
BR47395
KEGG:
R03001
MetaCyc:
2.6.1.41-RXN
|
|
|
|
glyoxylate + L-methionine <=> glycine + 4-methylsulfanyl-2-oxobutanoate
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.73
methionine---glyoxylate transaminase
|
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BR47428
KEGG:
R00652
MetaCyc:
METHIONINE--GLYOXYLATE-TRANSAMINASE-RXN
SABIO-RK:
1037
|
|
|
|
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 <=> H+ + 4-methylsulfanyl-2-oxobutanoate + formate
|
1.13.11.54
acireductone dioxygenase [iron(II)-requiring]
|
–
|
BMK
|
|
BRENDA:
BR48660
KEGG:
R07364
MetaCyc:
R147-RXN
|
|
|
|
L-glutamine + 4-methylsulfanyl-2-oxobutanoate <=> 2-Oxoglutaramate + L-methionine
|
2.6.1.117
L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
|
–
–
–
|
MK
|
|
BRENDA:
BR52923
KEGG:
R12507
MetaCyc:
RXN-15650
SABIO-RK:
10353
|
|
|
|
H+ + 4-methylsulfanyl-2-oxobutanoate <=> 3-methylthiopropionaldehyde + CO2
|
4.1.1.1
pyruvate decarboxylase
4.1.1.43
phenylpyruvate decarboxylase
4.1.1.7
benzoylformate decarboxylase
4.1.1.72
branched-chain-2-oxoacid decarboxylase
|
–
–
–
–
|
M
|
|
BRENDA:
BS1456
MetaCyc:
RXN-7704
|
|
|
|
L-methionine + 2-oxoglutarate <=> 4-methylsulfanyl-2-oxobutanoate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.2
alanine transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.6
leucine transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.73
methionine---glyoxylate transaminase
2.6.1.88
methionine transaminase
|
–
–
–
–
–
–
–
–
–
|
K
|
|
BRENDA:
BS353528
KEGG:
R07396
MetaCyc:
RXN-14147
|
|
|
|
L-tryptophan + 4-methylsulfanyl-2-oxobutanoate <=> 3-Indole-2-oxopropanoate + L-methionine
|
2.6.1
2.6.1.27
tryptophan transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.88
methionine transaminase
2.6.1.99
L-tryptophan---pyruvate aminotransferase
|
–
–
–
–
–
|
K
|
|
BRENDA:
BS353562
KEGG:
R12055
MetaCyc:
RXN-14685
|
|
|
|
L-methionine + phenylpyruvate <=> 4-methylsulfanyl-2-oxobutanoate + L-phenylalanine
|
2.6.1.14
asparagine---oxo-acid transaminase
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.28
tryptophan---phenylpyruvate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.58
phenylalanine(histidine) transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.88
methionine transaminase
|
–
–
–
–
–
–
–
–
–
–
|
BM
|
|
BRENDA:
BS353571
MetaCyc:
RXN-7708
SABIO-RK:
11201
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + acetyl-CoA + H2O <=> 2-[(2''-methylsulfanyl)ethyl]malate + CoA + H+
|
2.3.3.17
methylthioalkylmalate synthase
|
–
|
MK
|
|
BRENDA:
BS438092
KEGG:
R08619
MetaCyc:
RXN-2202
|
|
|
|
L-methionine + a_2-oxo_carboxylate <=> 4-methylsulfanyl-2-oxobutanoate + an_aliphatic_L-amino_acid
|
2.6.1.88
methionine transaminase
|
–
|
K
|
|
BRENDA:
BR49829
KEGG:
R08618
|
|
|
|
L-methionine + H2O + O2 <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
|
1.13.12.9
phenylalanine 2-monooxygenase
1.4.3.2
L-amino-acid oxidase
|
–
–
|
BK
|
|
BRENDA:
BS259010
KEGG:
R00648
SABIO-RK:
1033
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + NAD+ + CoA <=> 3-methylthiopropionyl-CoA + NADH + CO2
|
1.2.4.2
oxoglutarate dehydrogenase (succinyl-transferring)
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
–
|
|
|
BRENDA:
BS231869
SABIO-RK:
8166
|
|
|
|
L-methionine + H2O + NAD+ <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + NADH
|
1.4.1.1
alanine dehydrogenase
1.4.1.2
glutamate dehydrogenase
1.4.1.20
phenylalanine dehydrogenase
1.4.1.5
L-amino-acid dehydrogenase
1.4.1.8
valine dehydrogenase (NADP+)
1.4.1.9
leucine dehydrogenase
|
–
–
–
–
–
–
|
|
|
BRENDA:
BS232341
SABIO-RK:
7281
|
|
|
|
D-methionine + H2O + O2 <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
|
1.4.3.19
glycine oxidase
1.4.3.3
D-amino-acid oxidase
|
–
–
|
|
|
BRENDA:
BS259043
SABIO-RK:
6497
|
|
|
|
L-valine + 4-methylsulfanyl-2-oxobutanoate <=> 2-oxoisovalerate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.88
methionine transaminase
|
–
–
–
|
|
|
BRENDA:
BS353575
SABIO-RK:
12602
|
|
|
|
L-methionine + 4-methyl-2-oxopentanoate <=> 4-methylsulfanyl-2-oxobutanoate + L-leucine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.88
methionine transaminase
|
–
–
|
|
|
BRENDA:
BS356573
SABIO-RK:
12601
|
|
|
|
Se-methyl-L-selenocysteine + 4-methylsulfanyl-2-oxobutanoate <=> beta-methylselenopyruvate + L-methionine
|
2.6.1
|
–
|
K
|
|
KEGG:
R09373
|
|
|
|
L-methionine + a_2-oxo_carboxylate <=> 4-methylsulfanyl-2-oxobutanoate + proteinogenic_amino_acid
|
2.6.1.88
methionine transaminase
|
–
|
M
|
|
MetaCyc:
R15-RXN
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + H2O <=> ethylene + methanethiol + CO2
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-12539
|
|
|
|
(2R)-2-hydroxy-4-(methylsulfanyl)butanoate + NADP+ <=> 4-methylsulfanyl-2-oxobutanoate + NADPH + H+
|
1.1.1
|
–
|
M
|
|
MetaCyc:
RXN-9753
|
|
|
|
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 <=> 4-methylsulfanyl-2-oxobutanoate + formate + CO
|
1.13.11.53
acireductone dioxygenase (Ni2+-requiring)
|
–
|
|
|
BRENDA:
BS386947
|
|
|
|
L-leucine + a_2-oxo_carboxylate <=> 4-methylsulfanyl-2-oxobutanoate + an_aliphatic_L-amino_acid
|
2.6.1.88
methionine transaminase
|
–
|
|
|
BRENDA:
BS417159
|
|
|
|
L-tryptophan + 4-methylsulfanyl-2-oxobutanoate <=> 3-Indole-2-oxopropanoate + 2-aminomethylthiobutanoate
|
2.6.1.27
tryptophan transaminase
|
–
|
|
|
BRENDA:
BS437652
|
|
|
|
DL-methionine + H2O + O2 <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2
|
1.4.3.2
L-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS413362
|
|
|
|
D-methionine + H2O + 2,6-dichlorophenolindophenol <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + reduced_2,6-dichlorophenolindophenol
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS260520
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + CoA + oxidized_ferredoxin <=> 3-methylthio-2-oxopropanoyl-CoA + CO2 + reduced_ferredoxin
|
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
|
–
|
|
|
BRENDA:
BS359416
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + CoA + oxidized_ferredoxin <=> CO2 + reduced_ferredoxin + 3-methylthiopropionyl-CoA
|
1.2.7.8
indolepyruvate ferredoxin oxidoreductase
|
–
|
|
|
BRENDA:
BS359433
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + CoA + 2 methyl_viologen <=> 3-methylthiopropionyl-CoA + CO2 + 2 reduced_methyl_viologen + 2 H+
|
1.2.7.11
2-oxoacid oxidoreductase (ferredoxin)
|
–
|
|
|
BRENDA:
BS422433
|
|
|
|
DL-2-hydroxy-4-methylthiobutanoic_acid + 2,6-dichlorophenolindophenol <=> 4-methylsulfanyl-2-oxobutanoate + reduced_2,6-dichlorophenolindophenol
|
1.1.3.15
(S)-2-hydroxy-acid oxidase
|
–
|
|
|
BRENDA:
BS257457
|
|
|
|
D-methionine + 2,6-dichlorophenolindophenol <=> 4-methylsulfanyl-2-oxobutanoate + reduced_2,6-dichlorophenolindophenol
|
1.4.3.3
D-amino-acid oxidase
|
–
|
|
|
BRENDA:
BS414504
|
|
|
|
D-methionine + phenazine_methosulfate <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + reduced_phenazine_methosulfate
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS433614
|
|
|
|
D-methionine + 2-oxoglutarate <=> 4-methylsulfanyl-2-oxobutanoate + D-glutamate
|
2.6.1.21
D-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353647
|
|
|
|
D-methionine + 2-oxoglutarate <=> 4-methylsulfanyl-2-oxobutanoate + L-glutamate
|
2.6.1.41
D-methionine---pyruvate transaminase
|
–
|
|
|
BRENDA:
BS353614
|
|
|
|
D-methionine + oxidized_2,6-dichlorophenolindophenol + H2O <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + reduced_2,6-dichlorophenolindophenol
|
1.4.5.1
D-amino acid dehydrogenase (quinone)
1.4.99.6
D-arginine dehydrogenase
|
–
–
|
|
|
BRENDA:
BS404881
|
|
|
|
D-methionine + H2O + iodonitrotetrazolium_chloride <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + reduced_iodonitrotetrazolium_chloride
|
1.4.99.6
D-arginine dehydrogenase
|
–
|
|
|
BRENDA:
BS409165
|
|
|
|
D-methionine + oxidized_acceptor + H2O <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + reduced_acceptor
|
1.4.5.1
D-amino acid dehydrogenase (quinone)
|
–
|
|
|
BRENDA:
BS404883
|
|
|
|
D-methionine + 2-oxoadipate <=> 4-methylsulfanyl-2-oxobutanoate + 2-Aminoadipate
|
2.6.1.74
cephalosporin-C transaminase
|
–
|
|
|
BRENDA:
BS356887
|
|
|
|
L-kynurenine + 4-methylsulfanyl-2-oxobutanoate <=> Kynurenic_acid + L-methionine + H2O
|
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
|
|
|
BRENDA:
BS353515
|
|
|
|
L-methionine + 4-methylsulfanyl-2-oxobutanoate <=> 4-methylsulfanyl-2-oxobutanoate + L-methionine
|
2.6.1.73
methionine---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS353985
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-isoleucine <=> L-methionine + 2-oxomethylvalerate
|
2.6.1.88
methionine transaminase
|
–
|
|
|
BRENDA:
BS416167
|
|
|
|
2-oxosuccinamic_acid + L-methionine <=> L-asparagine + 4-methylsulfanyl-2-oxobutanoate
|
2.6.1.14
asparagine---oxo-acid transaminase
|
–
|
|
|
BRENDA:
BS354189
|
|
|
|
L-histidine + 4-methylsulfanyl-2-oxobutanoate <=> 3-(1H-imidazol-4-yl)-2-oxopropanoate + L-methionine
|
2.6.1.117
L-glutamine---4-(methylsulfanyl)-2-oxobutanoate aminotransferase
2.6.1.57
aromatic-amino-acid transaminase
|
–
–
|
|
|
BRENDA:
BS353577
|
|
|
|
S-(4-Bromophenyl)-L-cysteine + 4-methylsulfanyl-2-oxobutanoate <=> S-(4-Bromophenyl)-3-thiopyruvate + L-methionine
|
2.6.1.75
cysteine-conjugate transaminase
|
–
|
|
|
BRENDA:
BS356901
|
|
|
|
L-kynurenine + 4-methylsulfanyl-2-oxobutanoate <=> 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine
|
2.6.1.63
kynurenine---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS354010
|
|
|
|
L-2-aminobutanoate + 4-methylsulfanyl-2-oxobutanoate <=> 2-oxobutyrate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS379971
|
|
|
|
L-methionine + 2-oxobutyrate <=> 4-methylsulfanyl-2-oxobutanoate + 2-aminobutanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
|
|
|
BRENDA:
BS356571
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-tyrosine <=> L-methionine + 4-hydroxyphenylpyruvate
|
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.88
methionine transaminase
|
–
–
|
|
|
BRENDA:
BS353570
|
|
|
|
L-methionine + H2O + 2 cytochrome_b <=> 4-methylsulfanyl-2-oxobutanoate + NH3 + 2 reduced_cytochrome_b
|
1.4.99.B3
|
–
|
|
|
BRENDA:
BS439677
|
|
|
|
L-lysine + 4-methylsulfanyl-2-oxobutanoate <=> 6-Amino-2-oxohexanoate + L-methionine
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353578
|
|
|
|
L-cysteine + 4-methylsulfanyl-2-oxobutanoate <=> 3-Mercaptopyruvate + L-methionine
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353580
|
|
|
|
L-isoleucine + 4-methylsulfanyl-2-oxobutanoate <=> 3-methyl-2-oxopentanoate + L-methionine
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.57
aromatic-amino-acid transaminase
|
–
–
|
|
|
BRENDA:
BS353576
|
|
|
|
D-methionine + oxaloacetate <=> 4-methylsulfanyl-2-oxobutanoate + L-aspartate
|
2.6.1.41
D-methionine---pyruvate transaminase
|
–
|
|
|
BRENDA:
BS353613
|
|
|
|
L-aspartate + 4-methylsulfanyl-2-oxobutanoate <=> oxaloacetate + L-methionine
|
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.73
methionine---glyoxylate transaminase
|
–
–
|
|
|
BRENDA:
BS353581
|
|
|
|
L-glutamine + 4-methylsulfanyl-2-oxobutanoate <=> 2-oxoglutarate + L-methionine
|
2.6.1.73
methionine---glyoxylate transaminase
|
–
|
|
|
BRENDA:
BS353990
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-glutamine <=> 2-oxoglutaramide + L-methionine
|
2.6.1.57
aromatic-amino-acid transaminase
|
–
|
|
|
BRENDA:
BS353573
|
|
|
|
L-alanine + 4-methylsulfanyl-2-oxobutanoate <=> pyruvate + L-methionine
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.41
D-methionine---pyruvate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.73
methionine---glyoxylate transaminase
2.6.1.84
arginine---pyruvate transaminase
|
–
–
–
–
–
–
–
–
|
|
|
BRENDA:
BS353579
|
|
|
|
phenylpyruvate + DL-methionine <=> L-phenylalanine + 4-methylsulfanyl-2-oxobutanoate
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.28
tryptophan---phenylpyruvate transaminase
|
–
–
|
|
|
BRENDA:
BS356439
|
|
|
|
4-methylsulfanyl-2-oxobutanoate + L-isoleucine <=> L-methionine + (S)-3-methyl-2-oxopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
|
–
|
|
|
SABIO-RK:
12603
|
|