|
|
4-hydroxyphenylacetate + O2 + FADH2 <=> H+ + 3,4-Dihydroxyphenylacetate + H2O + FAD
|
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
|
BM
|
|
BRENDA:
BR40424
MetaCyc:
RXN-8505
|
|
|
|
4-chlorophenylacetate + NADH + O2 <=> 3,4-Dihydroxyphenylacetate + Cl- + NAD+
|
1.14.12.9
4-chlorophenylacetate 3,4-dioxygenase
|
–
|
K
|
|
BRENDA:
BR40438
KEGG:
R03306
MetaCyc:
1.14.12.9-RXN
|
|
|
|
O2 + 3,4-Dihydroxyphenylacetate <=> H+ + 5-carboxymethyl-2-hydroxymuconate_semialdehyde
|
1.13.11.15
3,4-dihydroxyphenylacetate 2,3-dioxygenase
|
–
|
BMK
|
|
BRENDA:
BR40487
KEGG:
R03303
MetaCyc:
1.13.11.15-RXN
SABIO-RK:
3120
|
|
|
|
3,4-dihydroxyphenylacetyl-CoA + H2O <=> 3,4-Dihydroxyphenylacetate + CoA + H+
|
3.1.2
3.1.2.20
acyl-CoA hydrolase
3.1.2.B5
|
–
–
–
|
|
|
BRENDA:
BR51133
MetaCyc:
RXN0-5065
SABIO-RK:
12733
|
|
|
|
3,4-dihydroxyphenylacetaldehyde + NAD+ + H2O <=> H+ + 3,4-Dihydroxyphenylacetate + NADH
|
1.2.1.29
aryl-aldehyde dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.39
phenylacetaldehyde dehydrogenase
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
|
–
–
–
–
|
MK
|
|
BRENDA:
BS231527
KEGG:
R03300
MetaCyc:
RXN6666-5
SABIO-RK:
3118
|
|
|
|
3,4-Dihydroxyphenylacetate + H+ <=> 4-methylcatechol + CO2
|
4.1.1.83
4-hydroxyphenylacetate decarboxylase
|
–
|
|
|
BRENDA:
BS375437
MetaCyc:
RXN-20409
SABIO-RK:
12325
|
|
|
|
4-hydroxyphenylacetate + NADH + O2 <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
|
1.14.12.9
4-chlorophenylacetate 3,4-dioxygenase
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
–
|
BK
|
|
BRENDA:
BS288372
KEGG:
R02698
|
|
|
|
S-adenosyl-L-methionine + 3,4-Dihydroxyphenylacetate <=> H+ + homovanillic_acid + S-adenosyl-L-homocysteine
|
2.1.1.6
catechol O-methyltransferase
|
–
|
MK
|
|
KEGG:
R03304
MetaCyc:
RXN6666-6
|
|
|
|
3,4-Dihydroxyphenylacetate + O2 <=> (3,4-dioxocyclohexa-1,5-dien-1-yl)acetic_acid + H2O
|
1.10.3.1
catechol oxidase
1.14.18.1
tyrosinase
|
–
–
|
|
|
BRENDA:
BS395684
SABIO-RK:
11654
|
|
|
|
3-hydroxyphenylacetate + O2 + NADH + H+ <=> 3,4-Dihydroxyphenylacetate + NAD+ + H2O
|
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
|
K
|
|
KEGG:
R03299
|
|
|
|
3,4-dihydroxyphenylacetaldehyde + NADP+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADPH + H+
|
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
|
–
|
K
|
|
KEGG:
R03302
|
|
|
|
4-chlorophenylacetate + ferricytochrome_c + H+ + O2 <=> 3,4-Dihydroxyphenylacetate + Cl- + ferricytochrome_c
|
1.14.12.9
4-chlorophenylacetate 3,4-dioxygenase
|
–
|
|
|
BRENDA:
BS451268
|
|
|
|
4-chlorophenylacetate + reduced_2,6-dichlorophenolindophenol + O2 <=> 3,4-Dihydroxyphenylacetate + Cl- + oxidized_2,6-dichlorophenolindophenol
|
1.14.12.9
4-chlorophenylacetate 3,4-dioxygenase
|
–
|
|
|
BRENDA:
BS451267
|
|
|
|
S-adenosyl-L-methionine + 3,4-Dihydroxyphenylacetate <=> S-adenosyl-L-homocysteine + homovanillic_acid + (3-hydroxy-4-methoxyphenyl)acetic_acid
|
2.1.1.6
catechol O-methyltransferase
|
–
|
|
|
BRENDA:
BS456356
|
|
|
|
3-Chlorophenylacetate + NADH + O2 + H2O <=> 3,4-Dihydroxyphenylacetate + Cl- + NAD+
|
1.14.12.9
4-chlorophenylacetate 3,4-dioxygenase
|
–
|
|
|
BRENDA:
BS288588
|
|
|
|
4-Fluorophenylacetate + NADH + O2 + H2O <=> 3,4-Dihydroxyphenylacetate + F- + NAD+
|
1.14.12.9
4-chlorophenylacetate 3,4-dioxygenase
|
–
|
|
|
BRENDA:
BS288587
|
|
|
|
3,4-Dihydroxyphenylacetate + NADH + O2 + H+ <=> 2,4,5-Trihydroxyphenylacetate + NAD+ + H2O
|
1.14.13.63
3-hydroxyphenylacetate 6-hydroxylase
|
–
|
|
|
BRENDA:
BS3095-a
|
|
|
|
4-Bromophenylacetate + NADH + O2 + H2O <=> 3,4-Dihydroxyphenylacetate + Br- + NAD+
|
1.14.12.9
4-chlorophenylacetate 3,4-dioxygenase
|
–
|
|
|
BRENDA:
BS288586
|
|
|
|
4-hydroxyphenylacetate + FMNH2 + O2 <=> 3,4-Dihydroxyphenylacetate + FMN + H2O
|
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
|
|
|
BRENDA:
BS427315
|
|
|
|
4-chlorophenylacetate + NADH + O2 + H2O <=> 3,4-Dihydroxyphenylacetate + Cl- + NADP+
|
1.14.12.9
4-chlorophenylacetate 3,4-dioxygenase
|
–
|
|
|
BRENDA:
BS288585
|
|
|
|
3,4-Dihydroxyphenylacetate + NADPH + O2 + H+ <=> 2,4,5-Trihydroxyphenylacetate + NADP+ + H2O
|
1.14.13.63
3-hydroxyphenylacetate 6-hydroxylase
|
–
|
|
|
BRENDA:
BS3095
|
|
|
|
4-hydroxyphenylacetate + NADPH + O2 <=> 3,4-Dihydroxyphenylacetate + NADP+ + H2O
|
1.14.14.9
4-hydroxyphenylacetate 3-monooxygenase
|
–
|
|
|
BRENDA:
BS288373
|
|
|
|
3,4-Dihydroxyphenylacetate + O2 <=> 2-hydroxy-5-carboxymethyl-cis,cis-muconate_semialdehyde
|
1.13.11.15
3,4-dihydroxyphenylacetate 2,3-dioxygenase
|
–
|
|
|
BRENDA:
BS371794
|
|
|
|
3,4-Dihydroxyphenylacetate + O2 <=> 2-hydroxy-5-5carboymethylmuconate_semialdehyde
|
1.13.11.15
3,4-dihydroxyphenylacetate 2,3-dioxygenase
|
–
|
|
|
BRENDA:
BS440100
|
|
|
|
3,4-Dihydroxyphenylacetate + O2 <=> 2-hydroxy-5-carboymethylmuconate_semialdehyde
|
1.13.11.15
3,4-dihydroxyphenylacetate 2,3-dioxygenase
|
–
|
|
|
BRENDA:
BS440754
|
|
|
|
3,4-Dihydroxyphenylpyruvate + O2 <=> 3,4-Dihydroxyphenylacetate + CO2
|
1.13.11.27
4-hydroxyphenylpyruvate dioxygenase
|
–
|
|
|
SABIO-RK:
11335
|
|
|
|
4-hydroxyphenylacetate + O2 <=> 3,4-Dihydroxyphenylacetate + H2O
|
1.14.18.1
tyrosinase
|
–
|
|
|
SABIO-RK:
11663
|
|