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sitosterol degradation to androstenedione

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
3-oxo-24-(isopropanoyl)-cholest-4,24-dien-26-oyl-CoA + H2O <=> 3,24-dioxo-cholest-4-en-26-oate + propionyl-CoA 3.1.2

22-hydroxy-3-oxochol-4-en-24-oyl-CoA <=> 3-oxochol-4,22-dien-24-oyl-CoA + H2O 4.2.1

3,24-dioxo-cholest-4-en-26-oate + ATP + CoA <=> 3,24-dioxocholest-4-en-26-oyl-CoA + AMP + diphosphate 6.2.1

3-oxo-24-ethyl-cholest-4-ene + O2 + NADH + H+ <=> 3-oxo-24-ethyl-26-hydroxy-cholest-4-ene + H2O + NAD+ 1.14.13

3-oxo-23,24-bisnorchol-4-en-22-oic_acid-CoA + acceptor <=> 3-oxo-23,24-bisnorchol-4,17(20)-dien-22-oyl-CoA + reduced_acceptor 1.3.99

3-oxo-24-ethyl-26-al-cholest-4-ene + NAD+ + H2O <=> 3-oxo-24-ethyl-cholest-4-en-26-oate + NADH + H+ 1.2.1

sitosterol + NAD+ <=> 3-oxo-24-ethyl-cholest-5-ene + NADH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase

3-oxo-24-ethyl-cholest-4,24-dien-26-oyl-CoA + HCO3- + ATP <=> 3-oxo-24-(isopropanoyl)-cholest-4,24-dien-26-oyl-CoA + ADP + phosphate + H+ 6.4.1

3-oxo-24-ethyl-26-hydroxy-cholest-4-ene + NAD+ <=> 3-oxo-24-ethyl-26-al-cholest-4-ene + NADH + H+ 1.1.1

3-oxo-24-ethyl-cholest-4-en-26-oate + CoA + ATP <=> 3-oxo-24-ethyl-cholest-4-en-26-oyl-CoA + AMP + diphosphate 6.2.1

3-oxochol-4-en-24-oyl-CoA + acceptor <=> 3-oxochol-4,22-dien-24-oyl-CoA + reduced_acceptor 1.3.99

22-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+ <=> 3,22-dioxochol-4-en-24-oyl-CoA + NADH + H+ 1.1.1

3-oxochol-4-en-24-oyl-CoA + propionyl-CoA <=> 3,24-dioxocholest-4-en-26-oyl-CoA + CoA 2.3.1.176 propanoyl-CoA C-acyltransferase

3-oxo-24-ethyl-cholest-5-ene <=> 3-oxo-24-ethyl-cholest-4-ene 5.3.3.1 steroid Delta-isomerase

17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA <=> 4-androstene-3,17-dione + propionyl-CoA 2.3.1

17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA <=> 3-oxo-23,24-bisnorchol-4,17(20)-dien-22-oyl-CoA + H2O 4.2.1

3-oxo-23,24-bisnorchol-4-en-22-oic_acid-CoA + acetyl-CoA <=> 3,22-dioxochol-4-en-24-oyl-CoA + CoA 2.3.1.16 acetyl-CoA C-acyltransferase

3-oxo-24-ethyl-cholest-4-en-26-oyl-CoA + acceptor <=> 3-oxo-24-ethyl-cholest-4,24-dien-26-oyl-CoA + reduced_acceptor 1.3.99

Visualization of the pathway