|
|
L-tryptophan + tetrahydropteridine + O2 <=> 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydropteridine
|
1.14.16.4
tryptophan 5-monooxygenase
|
–
|
| |
MetaCyc:
TRYPTOPHAN-5-MONOOXYGENASE-RXN
|
|
|
|
S-adenosyl-L-methionine + N-acetylserotonin <=> H+ + S-adenosyl-L-homocysteine + Melatonin
|
2.1.1.4
acetylserotonin O-methyltransferase
|
–
|
| |
BRENDA:
BR40580
KEGG:
R03130
MetaCyc:
ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN
SABIO-RK:
2965
|
|
|
|
acetyl-CoA + serotonin <=> H+ + CoA + N-acetylserotonin
|
2.3.1.5
arylamine N-acetyltransferase
2.3.1.87
aralkylamine N-acetyltransferase
|
–
–
|
| |
BRENDA:
BS320965
KEGG:
R02911
MetaCyc:
RXN3DJ-35528
SABIO-RK:
2771
|
|
|
|
5-hydroxy-L-tryptophan + H+ <=> serotonin + CO2
|
4.1.1.28
aromatic-L-amino-acid decarboxylase
4.1.1.53
phenylalanine decarboxylase
|
–
–
|
| |
BRENDA:
BR49520
KEGG:
R02701
MetaCyc:
RXN3DJ-170
|
|
