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salinosporamide A biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
3-(cyclohexa-1,3-dien-1-yl)-2-oxopropanoate + reduced_acceptor <=> 3-[(1S)-cyclohex-3-en-1-yl)]-2-oxopropanoate + acceptor not assigned
 –
3-[(1S)-cyclohex-3-en-1-yl)]-2-oxopropanoate + aminated_amino_group_donor <=> L-3-cyclohex-2''-enylalanine + deaminated_amino_group_donor 2.6.1
–
5''-chloro-5''-deoxyadenosine + phosphate <=> adenine + 5-chloro-5-deoxy-D-ribose_1-phosphate 2.4.2.1 purine-nucleoside phosphorylase
2.4.2.28 S-methyl-5'-thioadenosine phosphorylase
–
–
chorismate <=> prephenate 5.4.99.5 chorismate mutase
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5-chloro-5-deoxy-D-ribose + NAD+ <=> 5-chloro-5-deoxy-D-ribono-gamma-lactone + NADH + H+ not assigned
 –
chloroethylmalonyl-CoA + NAD+ <=> 4-chloro-crotonyl-CoA + CO2 + NADH 1.1.1
–
5-chloro-5-deoxy-D-ribose_1-phosphate + H2O <=> 5-chloro-5-deoxy-D-ribose + phosphate 3.1.3
–
acetyl-CoA + chloroethylmalonyl-CoA + L-3-cyclohex-2''-enylalanine + acceptor + H+ <=> salinosporamide_A + CoA + CO2 + reduced_acceptor 2.3.1
–
prephenate + reduced_acceptor <=> dehydroprephenate + acceptor not assigned
 –
5-chloro-4-hydroxy-2-oxopentanoate + CoA + oxidized_ferredoxin <=> 4-chloro-3-hydroxybutyryl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 4.1.1
–
5-chloro-5-deoxy-D-ribonate <=> 5-chloro-4-hydroxy-2-oxopentanoate + H2O 4.2.1
–
H+ + dehydroprephenate <=> 3-(cyclohexa-1,3-dien-1-yl)-2-oxopropanoate + CO2 + H2O not assigned
 –
S-adenosyl-L-methionine + Cl- <=> 5''-chloro-5''-deoxyadenosine + L-methionine 2.5.1.63 adenosyl-fluoride synthase
2.5.1.94 adenosyl-chloride synthase
–
–
5-chloro-5-deoxy-D-ribono-gamma-lactone + H2O <=> H+ + 5-chloro-5-deoxy-D-ribonate not assigned
 –
4-chloro-3-hydroxybutyryl-CoA <=> 4-chloro-crotonyl-CoA + H2O 4.2.1
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