|
|
P1,P4-bis(5''-xanthosyl)_tetraphosphate + H2O <=> XTP + XMP
|
3.6.1.17
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
|
–
|
| |
BRENDA:
BS141230
KEGG:
R02805
|
|
|
|
adenosine_5''-phosphosulfate + ATP <=> H+ + 3''-phosphoadenylyl-sulfate + ADP
|
2.7.1.25
adenylyl-sulfate kinase
|
–
|
| |
BRENDA:
BR47764
KEGG:
R00509
MetaCyc:
ADENYLYLSULFKIN-RXN
SABIO-RK:
237
|
|
|
|
5-hydroxyisourate + H2O <=> 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
|
3.5.2.17
hydroxyisourate hydrolase
|
–
|
| |
BRENDA:
BR48000
KEGG:
R06601
SABIO-RK:
6176
|
|
|
|
hypoxanthine + NAD+ + H2O <=> xanthine + NADH + H+
|
1.17.1.4
xanthine dehydrogenase
1.17.3.2
xanthine oxidase
|
–
–
|
| |
BRENDA:
BS359314
KEGG:
R01768
MetaCyc:
RXN-7682
SABIO-RK:
323
|
|
|
|
Xanthosine + phosphate <=> xanthine + alpha-D-ribose_1-phosphate
|
2.4.2
2.4.2.1
purine-nucleoside phosphorylase
|
–
–
|
| |
BRENDA:
BS323174
KEGG:
R02297
MetaCyc:
XANTHOSINEPHOSPHORY-RXN
|
|
|
|
H+ + H2O + guanine <=> NH3 + xanthine
|
3.5.4.3
guanine deaminase
|
–
|
| |
BRENDA:
BR22740
KEGG:
R01676
MetaCyc:
GUANINE-DEAMINASE-RXN
SABIO-RK:
127
|
|
|
|
IMP + NH3 + NADP+ <=> GMP + NADPH + H+
|
1.7.1.7
GMP reductase
|
–
|
| |
BRENDA:
BR36982
KEGG:
R01134
MetaCyc:
GMP-REDUCT-RXN
|
|
|
|
dITP + H2O <=> H+ + dIMP + diphosphate
|
3.6.1
3.6.1.66
XTP/dITP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
|
| |
BRENDA:
BR50709
KEGG:
R03531
MetaCyc:
RXN0-1602
SABIO-RK:
9408
|
|
|
|
P1,P4-bis(5''-adenosyl)_tetraphosphate + H2O <=> ATP + AMP + H+
|
3.1.4.1
phosphodiesterase I
3.6.1.17
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
3.6.1.29
bis(5'-adenosyl)-triphosphatase
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.61
diadenosine hexaphosphate hydrolase (ATP-forming)
3.6.1.71
adenosine-5'-diphospho-5'-[DNA] diphosphatase
3.6.1.9
nucleotide diphosphatase
6.1.1.14
glycine---tRNA ligase
|
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR49926
KEGG:
R00184
MetaCyc:
RXN-12820
SABIO-RK:
251
|
|
|
|
inosine_tetraphosphate + H2O <=> ITP + phosphate
|
3.6.1.11
exopolyphosphatase
3.6.1.14
adenosine-tetraphosphatase
|
–
–
|
| |
BRENDA:
BS141199
KEGG:
R00723
|
|
|
|
dADP + ATP <=> dATP + ADP
|
2.7.4.6
nucleoside-diphosphate kinase
|
–
|
| |
BRENDA:
BS358239
KEGG:
R01137
MetaCyc:
DADPKIN-RXN
|
|
|
|
GTP + H2O <=> H+ + GDP + phosphate
|
2.7.7.4
sulfate adenylyltransferase
3.1.3.2
acid phosphatase
3.1.3.5
5'-nucleotidase
3.6.1
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.3
adenosinetriphosphatase
3.6.1.5
apyrase
3.6.1.73
inosine/xanthosine triphosphatase
3.6.5.1
heterotrimeric G-protein GTPase
3.6.5.2
small monomeric GTPase
3.6.5.3
protein-synthesizing GTPase
3.6.5.4
signal-recognition-particle GTPase
3.6.5.5
dynamin GTPase
3.6.5.6
tubulin GTPase
7.1.2.1
P-type H+-exporting transporter
7.1.2.2
H+-transporting two-sector ATPase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR47963
KEGG:
R00335
MetaCyc:
RXN0-5462
SABIO-RK:
816
|
|
|
|
dADP + thioredoxin_disulfide + H2O <=> ADP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
| |
BRENDA:
BS287791
KEGG:
R02017
MetaCyc:
ADPREDUCT-RXN
|
|
|
|
P1,P4-bis(5''-guanosyl)_tetraphosphate + H2O <=> H+ + GTP + GMP
|
3.6.1.17
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
3.6.1.29
bis(5'-adenosyl)-triphosphatase
|
–
–
|
| |
BRENDA:
BR22757
KEGG:
R01232
MetaCyc:
3.6.1.17-RXN
SABIO-RK:
300
|
|
|
|
IMP + H2O + NAD+ <=> XMP + NADH + H+
|
1.1.1.205
IMP dehydrogenase
|
–
|
| |
BRENDA:
BR33666
KEGG:
R01130
MetaCyc:
IMP-DEHYDROG-RXN
SABIO-RK:
128
|
|
|
|
(S)-allantoin + H2O <=> H+ + Allantoate
|
3.5.2.5
allantoinase
|
–
|
| |
BRENDA:
BR26107
KEGG:
R02425
MetaCyc:
ALLANTOINASE-RXN
SABIO-RK:
2360
|
|
|
|
ATP + IDP <=> ITP + ADP
|
2.7.4.6
nucleoside-diphosphate kinase
|
–
|
| |
BRENDA:
BS358256
KEGG:
R00722
MetaCyc:
RXN-14120
|
|
|
|
inosine_5''-phosphobutyrate + H2O <=> Butyrate + IMP
|
3.6.1.20
5'-acylphosphoadenosine hydrolase
|
–
|
| |
BRENDA:
BS141268
KEGG:
R01690
|
|
|
|
pyruvate + dATP <=> phosphoenolpyruvate + dADP + H+
|
2.7.1.40
pyruvate kinase
|
–
|
| |
BRENDA:
BS411968
KEGG:
R01138
MetaCyc:
RXN-14192
SABIO-RK:
57
|
|
|
|
Benzoyl_adenylate + H2O <=> benzoate + AMP
|
3.6.1.20
5'-acylphosphoadenosine hydrolase
|
–
|
| |
BRENDA:
BS141264
KEGG:
R01423
|
|
|
|
oxamate + Carbamoyl_phosphate <=> phosphate + Oxalureate
|
2.1.3.5
oxamate carbamoyltransferase
|
–
|
| |
BRENDA:
BR43951
KEGG:
R02937
MetaCyc:
OXAMATE-CARBAMOYLTRANSFERASE-RXN
|
|
|
|
(S)-allantoin <=> (R)-allantoin
|
5.1.99.3
allantoin racemase
|
–
|
| |
BRENDA:
BR206
KEGG:
R03925
MetaCyc:
ALLANTOIN-RACEMASE-RXN
|
|
|
|
(S)-ureidoglycolate + NAD+ <=> Oxalureate + NADH + H+
|
1.1.1.154
ureidoglycolate dehydrogenase
1.1.1.350
ureidoglycolate dehydrogenase (NAD+)
|
–
–
|
| |
BRENDA:
BR29219-a;
BS450970
KEGG:
R02935
MetaCyc:
R165-RXN_WOP;
RXN0-7024
|
|
|
|
Inosine + ATP <=> H+ + IMP + ADP
|
2.7.1.145
deoxynucleoside kinase
2.7.1.20
adenosine kinase
2.7.1.73
inosine kinase
2.7.1.76
2'-deoxyadenosine kinase
2.7.1.B20
|
–
–
–
–
–
|
| |
BRENDA:
BR47800
KEGG:
R01131
MetaCyc:
INOSINEKIN-RXN
|
|
|
|
adenosine_2,3''-cyclic_monophosphate + H2O <=> adenosine_3''-monophosphate + H+
|
3.1.4.14
[acyl-carrier-protein] phosphodiesterase
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.1.4.17
3',5'-cyclic-nucleotide phosphodiesterase
3.1.4.55
phosphoribosyl 1,2-cyclic phosphate phosphodiesterase
3.1.4.56
7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase
3.6.1.13
ADP-ribose diphosphatase
|
–
–
–
–
–
–
|
| |
BRENDA:
BS399514
KEGG:
R03537
MetaCyc:
RXN-14113
SABIO-RK:
3322
|
|
|
|
IMP + diphosphate <=> hypoxanthine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
| |
BRENDA:
BR47537
KEGG:
R01132
MetaCyc:
HYPOXANPRIBOSYLTRAN-RXN
SABIO-RK:
81
|
|
|
|
xanthine + H2O <=> H+ + 5-ureido-4-imidazole_carboxylate
|
3.5.2
|
–
|
| |
KEGG:
R02141
MetaCyc:
R127-RXN
|
|
|
|
5-phosphoribosylamine + diphosphate + L-glutamate <=> 5-phospho-alpha-D-ribose_1-diphosphate + L-glutamine + H2O
|
2.4.2.14
amidophosphoribosyltransferase
|
–
|
| |
BRENDA:
BR44270
KEGG:
R01072
MetaCyc:
PRPPAMIDOTRANS-RXN
SABIO-RK:
114
|
|
|
|
H2O + dGTP <=> H+ + tripolyphosphate + 2''-deoxyguanosine
|
3.1.5.1
dGTPase
|
–
|
| |
BRENDA:
BR15965
KEGG:
R01856
MetaCyc:
DGTPTRIPHYDRO-RXN
SABIO-RK:
232
|
|
|
|
NH3 + HCO3- + ATP <=> Carbamoyl_phosphate + ADP + H2O + H+
|
2.7.2.2
carbamate kinase
|
–
|
| |
BRENDA:
BR47825
KEGG:
R00150
MetaCyc:
CARBAMATE-KINASE-RXN
|
|
|
|
H+ + ATP + ADP <=> phosphate + P1,P4-bis(5''-adenosyl)_tetraphosphate
|
2.7.7.53
ATP adenylyltransferase
|
–
|
| |
BRENDA:
BR47895
KEGG:
R00126
MetaCyc:
ATP-ADENYLYLTRANSFERASE-RXN
SABIO-RK:
248
|
|
|
|
pyruvate + GTP <=> phosphoenolpyruvate + GDP + H+
|
2.7.1.40
pyruvate kinase
|
–
|
| |
BRENDA:
BS357568
KEGG:
R00430
MetaCyc:
RXN-14117
SABIO-RK:
54
|
|
|
|
(S)-ureidoglycolate <=> Urea + glyoxylate
|
3.5.3.21
methylenediurea deaminase
3.5.3.4
allantoicase
4.3.2.3
ureidoglycolate lyase
|
–
–
–
|
| |
BRENDA:
BR3433;
BS17938
KEGG:
R00776
MetaCyc:
UREIDOGLYCOLATE-LYASE-RXN
SABIO-RK:
12069;
286
|
|
|
|
2''-deoxyinosine + phosphate <=> hypoxanthine + 2-deoxy-alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.4
thymidine phosphorylase
|
–
–
|
| |
BRENDA:
BS323151
KEGG:
R02748
MetaCyc:
DEOXYINOPHOSPHOR-RXN
SABIO-RK:
348
|
|
|
|
GDP + H2O <=> H+ + GMP + phosphate
|
3.1.3.2
acid phosphatase
3.6.1.42
guanosine-diphosphatase
3.6.1.5
apyrase
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.6
nucleoside diphosphate phosphatase
|
–
–
–
–
–
|
| |
BRENDA:
BR22773
KEGG:
R00328
MetaCyc:
GUANOSINE-DIPHOSPHATASE-RXN
SABIO-RK:
339
|
|
|
|
guanosine + H2O <=> D-ribose + guanine
|
3.2.2.1
purine nucleosidase
3.2.2.2
inosine nucleosidase
3.2.2.7
adenosine nucleosidase
3.2.2.8
ribosylpyrimidine nucleosidase
|
–
–
–
–
|
| |
BRENDA:
BS214500
KEGG:
R01677
MetaCyc:
RXN0-366
SABIO-RK:
321
|
|
|
|
GTP <=> cGMP + diphosphate
|
4.6.1.1
adenylate cyclase
4.6.1.2
guanylate cyclase
|
–
–
|
| |
BRENDA:
BR3451
KEGG:
R00434
MetaCyc:
GUANYLCYC-RXN
SABIO-RK:
294
|
|
|
|
adenosine + H2O + H+ <=> Inosine + NH3
|
3.5.4.4
adenosine deaminase
|
–
|
| |
BRENDA:
BR22741
KEGG:
R01560
MetaCyc:
ADENODEAMIN-RXN
SABIO-RK:
134
|
|
|
|
ADP + H2O <=> H+ + AMP + phosphate
|
3.1.15.1
venom exonuclease
3.1.3.1
alkaline phosphatase
3.1.3.10
glucose-1-phosphatase
3.1.3.2
acid phosphatase
3.1.3.26
4-phytase
3.1.3.31
nucleotidase
3.1.3.49
[pyruvate kinase]-phosphatase
3.1.3.5
5'-nucleotidase
3.1.3.8
3-phytase
3.1.4.1
phosphodiesterase I
3.1.4.12
sphingomyelin phosphodiesterase
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.1.4.37
2',3'-cyclic-nucleotide 3'-phosphodiesterase
3.6.1.1
inorganic diphosphatase
3.6.1.11
exopolyphosphatase
3.6.1.13
ADP-ribose diphosphatase
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.18
FAD diphosphatase
3.6.1.22
NAD+ diphosphatase
3.6.1.42
guanosine-diphosphatase
3.6.1.5
apyrase
3.6.1.53
Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
3.6.1.56
2-hydroxy-dATP diphosphatase
3.6.1.6
nucleoside diphosphate phosphatase
3.6.1.62
5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase
3.6.1.64
inosine diphosphate phosphatase
3.6.1.9
nucleotide diphosphatase
6.1.1.14
glycine---tRNA ligase
7.6.2.9
ABC-type quaternary amine transporter
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BS391186
KEGG:
R00122
MetaCyc:
RXN-10862
SABIO-RK:
246
|
|
|
|
L-aspartate + IMP + GTP <=> H+ + adenylosuccinate + phosphate + GDP
|
6.3.4.4
adenylosuccinate synthase
|
–
|
| |
BRENDA:
BR141
KEGG:
R01135
MetaCyc:
ADENYLOSUCCINATE-SYNTHASE-RXN
SABIO-RK:
228
|
|
|
|
H+ + Allantoate + H2O <=> (S)-ureidoglycine + NH3 + CO2
|
3.5.3.9
allantoate deiminase
|
–
|
| |
BRENDA:
BR26110
KEGG:
R02423
MetaCyc:
ALLANTOATE-DEIMINASE-RXN
|
|
|
|
P1,P3-bis(5''-adenosyl)_triphosphate + H2O <=> H+ + AMP + ADP
|
3.1.4.1
phosphodiesterase I
3.6.1.17
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
3.6.1.29
bis(5'-adenosyl)-triphosphatase
3.6.1.41
bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
3.6.1.71
adenosine-5'-diphospho-5'-[DNA] diphosphatase
3.6.1.9
nucleotide diphosphatase
6.1.1.14
glycine---tRNA ligase
|
–
–
–
–
–
–
–
|
| |
BRENDA:
BR29527;
BS165343;
BS453422
KEGG:
R00187
MetaCyc:
BIS5-ADENOSYL-TRIPHOSPHATASE-RXN
SABIO-RK:
735
|
|
|
|
ATP + D-ribose_5-phosphate + NH3 <=> ADP + phosphate + 5-phosphoribosylamine + H+
|
6.3.4.7
ribose-5-phosphate---ammonia ligase
|
–
|
| |
BRENDA:
BR144
KEGG:
R01053
MetaCyc:
RIBOSE-5-PHOSPHATE--AMMONIA-LIGASE-RXN
|
|
|
|
dGMP + H2O <=> 2''-deoxyguanosine + phosphate
|
3.1.3.2
acid phosphatase
3.1.3.31
nucleotidase
3.1.3.35
thymidylate 5'-phosphatase
3.1.3.5
5'-nucleotidase
3.1.3.6
3'-nucleotidase
3.1.3.89
5'-deoxynucleotidase
3.6.1.11
exopolyphosphatase
|
–
–
–
–
–
–
–
|
| |
BRENDA:
BS64635
KEGG:
R01968
MetaCyc:
RXN-14142
SABIO-RK:
304
|
|
|
|
IMP + H2O <=> hypoxanthine + D-ribose_5-phosphate
|
3.2.2.1
purine nucleosidase
3.2.2.12
inosinate nucleosidase
|
–
–
|
| |
BRENDA:
BR16039
KEGG:
R01128
MetaCyc:
INOSINATE-NUCLEOSIDASE-RXN
|
|
|
|
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate <=> (S)-allantoin + CO2
|
4.1.1.97
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
|
–
|
| |
BRENDA:
BR50998
KEGG:
R06604
|
|
|
|
IMP + H2O <=> Inosine + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.99
IMP-specific 5'-nucleotidase
|
–
–
–
–
–
|
| |
BRENDA:
BR51619
KEGG:
R01126
MetaCyc:
RXN-7607
SABIO-RK:
124
|
|
|
|
formate + GTP + H+ <=> dGTP + CO2 + H2O
|
1.1.98.6
ribonucleoside-triphosphate reductase (formate)
|
–
|
| |
BRENDA:
BS439595
KEGG:
R11633
MetaCyc:
RXN0-746
|
|
|
|
adenosine_5'-phosphosulfate + ATP <=> sulfate + P1,P4-Bis(5''-adenosyl)tetraphosphate
|
2.7.7.53
ATP adenylyltransferase
|
–
|
| |
KEGG:
R01618
|
|
|
|
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate <=> H+ + ADP + phosphate + 5''-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole
|
6.3.2.6
phosphoribosylaminoimidazolesuccinocarboxamide synthase
|
–
|
| |
BRENDA:
BR122
KEGG:
R04591
MetaCyc:
SAICARSYN-RXN
|
|
|
|
ITP + H2O <=> IDP + phosphate + H+
|
3.1.3.2
acid phosphatase
3.1.3.5
5'-nucleotidase
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.28
thiamine-triphosphatase
3.6.1.3
adenosinetriphosphatase
3.6.1.5
apyrase
3.6.1.6
nucleoside diphosphate phosphatase
3.6.1.62
5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase
3.6.1.64
inosine diphosphate phosphatase
3.6.1.66
XTP/dITP diphosphatase
3.6.1.73
inosine/xanthosine triphosphatase
3.6.1.9
nucleotide diphosphatase
3.6.4.13
RNA helicase
3.6.5.3
protein-synthesizing GTPase
3.6.5.6
tubulin GTPase
7.1.2.1
P-type H+-exporting transporter
7.1.2.2
H+-transporting two-sector ATPase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR53049
KEGG:
R00719
MetaCyc:
RXN0-5073
SABIO-RK:
1090
|
|
|
|
adenosine + phosphate <=> adenine + alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
2.4.2.44
S-methyl-5'-thioinosine phosphorylase
|
–
–
–
|
| |
BRENDA:
BS323170
KEGG:
R01561
MetaCyc:
ADENPHOSPHOR-RXN
SABIO-RK:
133
|
|
|
|
adenosine_3''-monophosphate + H2O <=> adenosine + phosphate
|
3.1.21.1
deoxyribonuclease I
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.25
inositol-phosphate phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.6
3'-nucleotidase
3.1.30.1
Aspergillus nuclease S1
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.6.1.1
inorganic diphosphatase
3.6.1.11
exopolyphosphatase
|
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BS364421
KEGG:
R01562
MetaCyc:
RXN-14126
SABIO-RK:
305
|
|
|
|
Inosine + H2O <=> D-ribose + hypoxanthine
|
3.2.2.1
purine nucleosidase
3.2.2.2
inosine nucleosidase
3.2.2.7
adenosine nucleosidase
3.2.2.8
ribosylpyrimidine nucleosidase
|
–
–
–
–
|
| |
BRENDA:
BR16042
KEGG:
R01770
MetaCyc:
INOSINE-NUCLEOSIDASE-RXN
|
|
|
|
2''-deoxyadenosine + phosphate <=> adenine + 2-deoxy-alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
|
–
–
|
| |
BRENDA:
BS323171;
BS395330
KEGG:
R02557
MetaCyc:
DEOXYADENPHOSPHOR-RXN
SABIO-RK:
342
|
|
|
|
5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + HCO3- <=> H+ + 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate
|
6.3.4.18
5-(carboxyamino)imidazole ribonucleotide synthase
|
–
|
| |
BRENDA:
BR48708
KEGG:
R07404
MetaCyc:
RXN0-742
|
|
|
|
xanthine + NAD+ + H2O <=> Urate + NADH + H+
|
1.17.1.4
xanthine dehydrogenase
1.17.3.2
xanthine oxidase
|
–
–
|
| |
BRENDA:
BR48027
KEGG:
R02103
MetaCyc:
RXN0-901
SABIO-RK:
196
|
|
|
|
AMP + diphosphate <=> adenine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
| |
BRENDA:
BR47515
KEGG:
R00190
MetaCyc:
ADENPRIBOSYLTRAN-RXN
SABIO-RK:
80
|
|
|
|
H+ + H2O + adenine <=> NH3 + hypoxanthine
|
3.5.4.2
adenine deaminase
|
–
|
| |
BRENDA:
BR19264
KEGG:
R01244
MetaCyc:
ADENINE-DEAMINASE-RXN
SABIO-RK:
131
|
|
|
|
GDP + ATP <=> GTP + ADP
|
2.7.4.6
nucleoside-diphosphate kinase
2.7.4.8
guanylate kinase
|
–
–
|
| |
BRENDA:
BS358258
KEGG:
R00330
MetaCyc:
GDPKIN-RXN
SABIO-RK:
138
|
|
|
|
5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + H+ <=> 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2
|
4.1.1.21
phosphoribosylaminoimidazole carboxylase
5.4.99.18
5-(carboxyamino)imidazole ribonucleotide mutase
|
–
–
|
| |
BRENDA:
BR282
KEGG:
R04209
MetaCyc:
AIRCARBOXY-RXN
SABIO-RK:
119
|
|
|
|
GMP + diphosphate <=> guanine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
| |
BRENDA:
BS354829
KEGG:
R01229
MetaCyc:
GUANPRIBOSYLTRAN-RXN
SABIO-RK:
195
|
|
|
|
ADP-ribose + H2O <=> AMP + alpha-D-ribose_1-phosphate + H+
|
3.6.1.21
ADP-sugar diphosphatase
3.6.1.45
UDP-sugar diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
|
| |
BRENDA:
BS372275
KEGG:
R01885
MetaCyc:
RXN-10763
|
|
|
|
dGDP + thioredoxin_disulfide + H2O <=> GDP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
| |
BRENDA:
BS287796
KEGG:
R02019
MetaCyc:
GDPREDUCT-RXN
|
|
|
|
5-aminoimidazole-4-carboxamide_ribonucleotide + diphosphate <=> 5-aminoimidazole-4-carboxamide + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.7
adenine phosphoribosyltransferase
|
–
|
| |
BRENDA:
BS355041
KEGG:
R04378
MetaCyc:
RXN-14270
|
|
|
|
dIDP + H2O <=> dIMP + phosphate + H+
|
3.6.1.64
inosine diphosphate phosphatase
|
–
|
| |
BRENDA:
BR50470
KEGG:
R10235
MetaCyc:
RXN-14004
|
|
|
|
cAMP + H2O <=> H+ + AMP
|
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.1.4.17
3',5'-cyclic-nucleotide phosphodiesterase
3.1.4.35
3',5'-cyclic-GMP phosphodiesterase
3.1.4.42
glycerol-1,2-cyclic-phosphate 2-phosphodiesterase
3.1.4.53
3',5'-cyclic-AMP phosphodiesterase
3.6.1.1
inorganic diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
–
–
–
|
| |
BRENDA:
BR48778
KEGG:
R00191
MetaCyc:
RXN0-5038
SABIO-RK:
292
|
|
|
|
guanosine + phosphate <=> guanine + alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.15
guanosine phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
|
–
–
–
|
| |
BRENDA:
BR44271
KEGG:
R02147
MetaCyc:
RXN0-5199
SABIO-RK:
187
|
|
|
|
XMP + diphosphate <=> xanthine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
| |
BRENDA:
BR47505
KEGG:
R02142
MetaCyc:
XANPRIBOSYLTRAN-RXN
SABIO-RK:
194
|
|
|
|
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+ <=> (R)-allantoin + CO2
|
not assigned
|
–
|
| |
KEGG:
R06605
|
|
|
|
adenosine + ATP <=> H+ + AMP + ADP
|
2.7.1.11
6-phosphofructokinase
2.7.1.145
deoxynucleoside kinase
2.7.1.20
adenosine kinase
2.7.1.74
deoxycytidine kinase
2.7.1.76
2'-deoxyadenosine kinase
2.7.1.B20
|
–
–
–
–
–
–
|
| |
BRENDA:
BR47760
KEGG:
R00185
MetaCyc:
ADENOSINE-KINASE-RXN
SABIO-RK:
252
|
|
|
|
H2O + ATP <=> H+ + diphosphate + AMP
|
3.1.4.1
phosphodiesterase I
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
6.1.1.1
tyrosine---tRNA ligase
|
–
–
–
–
|
| |
BRENDA:
BR22781
KEGG:
R00087
MetaCyc:
ATP-PYROPHOSPHATASE-RXN
SABIO-RK:
245
|
|
|
|
guanosine_3''-monophosphate + H2O <=> guanosine + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.25
inositol-phosphate phosphatase
3.1.3.31
nucleotidase
3.1.3.6
3'-nucleotidase
3.1.30.1
Aspergillus nuclease S1
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
|
–
–
–
–
–
–
–
|
| |
BRENDA:
BS64647
KEGG:
R02148
MetaCyc:
RXN-14124
SABIO-RK:
309
|
|
|
|
IDP + H2O <=> IMP + phosphate + H+
|
3.6.1.5
apyrase
3.6.1.6
nucleoside diphosphate phosphatase
3.6.1.64
inosine diphosphate phosphatase
|
–
–
–
|
| |
BRENDA:
BR50469
KEGG:
R00961
MetaCyc:
RXN-14003
|
|
|
|
(S)-ureidoglycine + glyoxylate <=> Oxalureate + glycine
|
2.6.1.112
(S)-ureidoglycine---glyoxylate transaminase
|
–
|
| |
BRENDA:
BR51975
KEGG:
R10908
MetaCyc:
RXN-11141
|
|
|
|
H+ + sulfate + ATP <=> adenosine_5''-phosphosulfate + diphosphate
|
2.7.7.4
sulfate adenylyltransferase
|
–
|
| |
BRENDA:
BR47884
KEGG:
R00529
MetaCyc:
SULFATE-ADENYLYLTRANS-RXN
SABIO-RK:
947
|
|
|
|
dATP + thioredoxin_disulfide + H2O <=> ATP + thioredoxin
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
| |
BRENDA:
BS287787
KEGG:
R02014
MetaCyc:
RXN-21262
SABIO-RK:
2051
|
|
|
|
10-formyltetrahydrofolate + beta-glycinamide_ribonucleotide <=> tetrahydrofolate + formylglycinamide_ribonucleotide + H+
|
2.1.2.2
phosphoribosylglycinamide formyltransferase
|
–
|
| |
BRENDA:
BR43941
KEGG:
R04325
MetaCyc:
GART-RXN
|
|
|
|
ATP + AMP <=> ADP
|
1.13.12.7
firefly luciferase
2.7.1.20
adenosine kinase
2.7.4.10
nucleoside-triphosphate---adenylate kinase
2.7.4.11
(deoxy)adenylate kinase
2.7.4.14
UMP/CMP kinase
2.7.4.3
adenylate kinase
2.7.4.31
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
2.7.4.4
nucleoside-phosphate kinase
2.7.4.8
guanylate kinase
2.7.4.9
dTMP kinase
|
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR47850
KEGG:
R00127
MetaCyc:
ADENYL-KIN-RXN
SABIO-RK:
82
|
|
|
|
AMP + H2O <=> adenosine + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.10
glucose-1-phosphatase
3.1.3.102
FMN hydrolase
3.1.3.2
acid phosphatase
3.1.3.26
4-phytase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.6
3'-nucleotidase
3.1.3.8
3-phytase
3.1.3.89
5'-deoxynucleotidase
3.6.1.11
exopolyphosphatase
3.6.1.22
NAD+ diphosphatase
3.6.1.45
UDP-sugar diphosphatase
3.6.1.5
apyrase
3.6.1.9
nucleotide diphosphatase
5.6.1.7
chaperonin ATPase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BS399878
KEGG:
R00183
MetaCyc:
AMP-DEPHOSPHORYLATION-RXN
SABIO-RK:
295
|
|
|
|
Xanthosine + H2O <=> D-ribose + xanthine
|
3.2.2.1
purine nucleosidase
3.2.2.2
inosine nucleosidase
3.2.2.3
uridine nucleosidase
3.2.2.8
ribosylpyrimidine nucleosidase
|
–
–
–
–
|
| |
BRENDA:
BS214506
KEGG:
R02143
MetaCyc:
RXN0-363
|
|
|
|
cGMP + H2O <=> H+ + GMP
|
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.1.4.17
3',5'-cyclic-nucleotide phosphodiesterase
3.1.4.35
3',5'-cyclic-GMP phosphodiesterase
3.1.4.53
3',5'-cyclic-AMP phosphodiesterase
|
–
–
–
–
|
| |
BRENDA:
BR15958
KEGG:
R01234
MetaCyc:
35-CYCLIC-GMP-PHOSPHODIESTERASE-RXN
SABIO-RK:
293
|
|
|
|
Urate + NADH + H+ + O2 <=> 5-hydroxyisourate + NAD+ + H2O
|
1.14.13.113
FAD-dependent urate hydroxylase
|
–
|
| |
BRENDA:
BR49110
KEGG:
R09514
|
|
|
|
H2O + adenosine <=> D-ribose + adenine
|
3.2.2.1
purine nucleosidase
3.2.2.16
methylthioadenosine nucleosidase
3.2.2.2
inosine nucleosidase
3.2.2.22
rRNA N-glycosylase
3.2.2.30
aminodeoxyfutalosine nucleosidase
3.2.2.7
adenosine nucleosidase
3.2.2.8
ribosylpyrimidine nucleosidase
3.2.2.9
adenosylhomocysteine nucleosidase
|
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR16044
KEGG:
R01245
MetaCyc:
ADENOSINE-NUCLEOSIDASE-RXN
|
|
|
|
guanosine_2,3''-cyclic_monophosphate + H2O <=> guanosine_3''-monophosphate + H+
|
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.1.4.55
phosphoribosyl 1,2-cyclic phosphate phosphodiesterase
4.6.1.24
ribonuclease T1
|
–
–
–
|
| |
BRENDA:
BS12776
KEGG:
R05135
MetaCyc:
RXN-14064
SABIO-RK:
4755
|
|
|
|
ATP + GMP <=> ADP + GDP
|
2.7.4.8
guanylate kinase
|
–
|
| |
BRENDA:
BR47853
KEGG:
R00332
MetaCyc:
GUANYL-KIN-RXN
SABIO-RK:
77
|
|
|
|
uric_acid_ribonucleoside + phosphate <=> alpha-D-ribose_1-phosphate + Urate
|
2.4.2.16
urate-ribonucleoside phosphorylase
|
–
|
| |
BRENDA:
BR47658;
BS356200
KEGG:
R02646
MetaCyc:
URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN
|
|
|
|
H+ + H2O + 2''-deoxyadenosine <=> NH3 + 2''-deoxyinosine
|
3.5.4.17
adenosine-phosphate deaminase
3.5.4.18
ATP deaminase
3.5.4.4
adenosine deaminase
|
–
–
–
|
| |
BRENDA:
BS141041
KEGG:
R02556
MetaCyc:
ADDALT-RXN
SABIO-RK:
281
|
|
|
|
imidazolinone + H2O <=> Formiminoglycine
|
3.5.2
|
–
|
| |
KEGG:
R04026
MetaCyc:
R63-RXN
|
|
|
|
5-ureido-4-imidazole_carboxylate + H2O + H+ <=> 5-amino-4-imidazole_carboxylate + CO2 + NH3
|
3.5.1
3.5.3
|
–
–
|
| |
KEGG:
R04857
MetaCyc:
R128-RXN
|
|
|
|
5-phosphoribosylamine + ATP + glycine <=> H+ + ADP + phosphate + beta-glycinamide_ribonucleotide
|
6.3.4.13
phosphoribosylamine---glycine ligase
|
–
|
| |
BRENDA:
BR134
KEGG:
R04144
MetaCyc:
GLYRIBONUCSYN-RXN
|
|
|
|
Inosine + phosphate <=> hypoxanthine + alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.15
guanosine phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
2.4.2.3
uridine phosphorylase
2.4.2.44
S-methyl-5'-thioinosine phosphorylase
|
–
–
–
–
–
|
| |
BRENDA:
BS323149
KEGG:
R01863
MetaCyc:
INOPHOSPHOR-RXN
SABIO-RK:
125
|
|
|
|
dGTP + H2O <=> H+ + dGMP + diphosphate
|
3.6.1
3.6.1.23
dUTP diphosphatase
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.56
2-hydroxy-dATP diphosphatase
3.6.1.65
(d)CTP diphosphatase
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
–
–
–
|
| |
BRENDA:
BS141253
KEGG:
R01855
MetaCyc:
RXN0-385
SABIO-RK:
302
|
|
|
|
H2O + Allantoate <=> (S)-ureidoglycolate + Urea
|
3.5.3.4
allantoicase
|
–
|
| |
BRENDA:
BR19262;
BS381376
KEGG:
R02422
MetaCyc:
ALLANTOICASE-RXN
SABIO-RK:
219
|
|
|
|
xanthine + O2 + H2O <=> Urate + H2O2
|
1.17.3.2
xanthine oxidase
1.2.3.1
aldehyde oxidase
|
–
–
|
| |
BRENDA:
BR48028
KEGG:
R02107
MetaCyc:
XANTHINE-OXIDASE-RXN
SABIO-RK:
192
|
|
|
|
H+ + H2O + (S)-ureidoglycolate <=> NH3 + CO2 + glyoxylate
|
3.5.1.116
ureidoglycolate amidohydrolase
|
–
|
| |
BRENDA:
BR29521;
BS190021
KEGG:
R00469
MetaCyc:
UREIDOGLYCOLATE-HYDROLASE-RXN
SABIO-RK:
230
|
|
|
|
H2O + adenosine_5'-tetraphosphate <=> phosphate + ATP + H+
|
3.6.1.14
adenosine-tetraphosphatase
3.6.1.17
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
|
–
–
|
| |
BRENDA:
BR22754
KEGG:
R00128
MetaCyc:
ADENOSINE-TETRAPHOSPHATASE-RXN
|
|
|
|
XMP + H2O <=> Xanthosine + phosphate
|
3.1.3.5
5'-nucleotidase
|
–
|
| |
BRENDA:
BS383410
KEGG:
R02719
MetaCyc:
XMPXAN-RXN
SABIO-RK:
129
|
|
|
|
ITP + H2O <=> IMP + diphosphate + H+
|
3.6.1
3.6.1.66
XTP/dITP diphosphatase
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
|
| |
BRENDA:
BS141249
KEGG:
R00720
MetaCyc:
RXN0-6382
SABIO-RK:
297
|
|
|
|
4-aminoimidazole + H2O + H+ <=> NH3 + imidazolinone
|
3.5.4.8
aminoimidazolase
|
–
|
| |
BRENDA:
BR22745
KEGG:
R04731
MetaCyc:
R13-RXN
|
|
|
|
5''-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole <=> fumarate + 5-aminoimidazole-4-carboxamide_ribonucleotide
|
4.3.2.2
adenylosuccinate lyase
|
–
|
| |
BRENDA:
BR12741
KEGG:
R04559
MetaCyc:
AICARSYN-RXN
SABIO-RK:
121
|
|
|
|
ATP + formylglycinamide_ribonucleotide + L-glutamine + H2O <=> H+ + L-glutamate + ADP + phosphate + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine
|
6.3.5.3
phosphoribosylformylglycinamidine synthase
|
–
|
| |
BRENDA:
BR150
KEGG:
R04463
MetaCyc:
FGAMSYN-RXN
|
|
|
|
acetyl_adenylate + H2O <=> acetate + AMP
|
3.6.1.20
5'-acylphosphoadenosine hydrolase
|
–
|
| |
BRENDA:
BS141266
KEGG:
R00322
|
|
|
|
H2O + guanosine_3'-diphosphate_5'-triphosphate <=> H+ + phosphate + ppGpp
|
3.6.1.11
exopolyphosphatase
3.6.1.40
guanosine-5'-triphosphate,3'-diphosphate phosphatase
|
–
–
|
| |
BRENDA:
BR29528
KEGG:
R03409
MetaCyc:
PPPGPPHYDRO-RXN
|
|
|
|
oxamate + H2O <=> oxalate + NH3
|
3.5.1.126
oxamate amidohydrolase
|
–
|
| |
BRENDA:
BR51989
KEGG:
R11617
MetaCyc:
RXN-9509
|
|
|
|
ADP + ATP <=> ATP + ADP
|
2.4.2.12
nicotinamide phosphoribosyltransferase
2.7.1.20
adenosine kinase
2.7.4.6
nucleoside-diphosphate kinase
3.6.4.10
non-chaperonin molecular chaperone ATPase
|
–
–
–
–
|
| |
BRENDA:
BS141550
KEGG:
R00124
|
|
|
|
10-formyltetrahydrofolate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide
|
2.1.2.3
phosphoribosylaminoimidazolecarboxamide formyltransferase
|
–
|
| |
BRENDA:
BR43942
KEGG:
R04560
MetaCyc:
AICARTRANSFORM-RXN
SABIO-RK:
122
|
|
|
|
dAMP + H2O <=> 2''-deoxyadenosine + phosphate
|
3.1.3.2
acid phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.89
5'-deoxynucleotidase
|
–
–
–
–
|
| |
BRENDA:
BS391800
KEGG:
R02088
MetaCyc:
RXN-14161
SABIO-RK:
282
|
|
|
|
GTP + H2O <=> GMP + diphosphate + H+
|
3.6.1
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.56
2-hydroxy-dATP diphosphatase
3.6.1.65
(d)CTP diphosphatase
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
–
–
|
| |
BRENDA:
BS141252
KEGG:
R00426
MetaCyc:
RXN-14140
SABIO-RK:
301
|
|
|
|
5-amino-4-imidazole_carboxylate <=> 4-aminoimidazole + CO2
|
4.1.1
|
–
|
| |
KEGG:
R04732
MetaCyc:
R62-RXN
|
|
|
|
formate + ATP + H+ <=> CO2 + dATP + H2O
|
1.1.98.6
ribonucleoside-triphosphate reductase (formate)
|
–
|
| |
BRENDA:
BS439175
KEGG:
R11634
MetaCyc:
RXN0-745
|
|
|
|
H2O + P1,P4-bis(5''-adenosyl)_tetraphosphate <=> H+ + ADP
|
3.6.1.41
bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
|
–
|
| |
BRENDA:
BR26123
KEGG:
R00125
MetaCyc:
3.6.1.41-RXN
|
|
|
|
5-formimidoyltetrahydrofolate + glycine <=> Formiminoglycine + tetrahydrofolate
|
2.1.2.4
glycine formimidoyltransferase
|
–
|
| |
BRENDA:
BR43943
KEGG:
R02729
MetaCyc:
GLYCINE-FORMIMINOTRANSFERASE-RXN
|
|
|
|
GMP + H2O <=> guanosine + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.25
inositol-phosphate phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.6
3'-nucleotidase
3.1.3.89
5'-deoxynucleotidase
3.6.1.11
exopolyphosphatase
|
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BS401104
KEGG:
R01227
MetaCyc:
RXN-7609
SABIO-RK:
186
|
|
|
|
XMP + H2O + L-glutamine + ATP <=> H+ + L-glutamate + GMP + diphosphate + AMP
|
6.3.5.2
GMP synthase (glutamine-hydrolysing)
|
–
|
| |
BRENDA:
BR149
KEGG:
R01231
MetaCyc:
GMP-SYN-GLUT-RXN
SABIO-RK:
215
|
|
|
|
pyruvate + ATP <=> H+ + phosphoenolpyruvate + ADP
|
2.7.1.40
pyruvate kinase
|
–
|
| |
BRENDA:
BR47778
KEGG:
R00200
MetaCyc:
PEPDEPHOS-RXN
SABIO-RK:
9
|
|
|
|
ATP + dGMP <=> ADP + dGDP
|
2.7.4.12
T2-induced deoxynucleotide kinase
2.7.4.13
(deoxy)nucleoside-phosphate kinase
2.7.4.25
(d)CMP kinase
2.7.4.8
guanylate kinase
2.7.4.9
dTMP kinase
2.7.4.B1
|
–
–
–
–
–
–
|
| |
BRENDA:
BR47842
KEGG:
R02090
MetaCyc:
GMKALT-RXN
SABIO-RK:
303
|
|
|
|
ATP <=> cAMP + diphosphate
|
4.6.1.1
adenylate cyclase
4.6.1.2
guanylate cyclase
|
–
–
|
| |
BRENDA:
BR3450
KEGG:
R00089
MetaCyc:
ADENYLATECYC-RXN
SABIO-RK:
101
|
|
|
|
2''-deoxyadenosine + ATP <=> H+ + dAMP + ADP
|
2.7.1.113
deoxyguanosine kinase
2.7.1.145
deoxynucleoside kinase
2.7.1.20
adenosine kinase
2.7.1.21
thymidine kinase
2.7.1.74
deoxycytidine kinase
2.7.1.76
2'-deoxyadenosine kinase
2.7.1.B20
|
–
–
–
–
–
–
–
|
| |
BRENDA:
BR47802
KEGG:
R02089
MetaCyc:
DEOXYADENOSINE-KINASE-RXN
SABIO-RK:
279
|
|
|
|
5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole <=> 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate
|
5.4.99.18
5-(carboxyamino)imidazole ribonucleotide mutase
|
–
|
| |
BRENDA:
BR48707
KEGG:
R07405
MetaCyc:
RXN0-743
SABIO-RK:
9083
|
|
|
|
(S)-ureidoglycolate + NADP+ <=> Oxalureate + NADPH + H+
|
1.1.1.154
ureidoglycolate dehydrogenase
|
–
|
| |
BRENDA:
BR29219
KEGG:
R02936
MetaCyc:
R165-RXN
|
|
|
|
hypoxanthine + O2 + H2O <=> xanthine + H2O2
|
1.17.1.4
xanthine dehydrogenase
1.17.3.2
xanthine oxidase
1.2.3.1
aldehyde oxidase
|
–
–
–
|
| |
BRENDA:
BS258274
KEGG:
R01769
|
|
|
|
Urate + O2 + H2O <=> 5-hydroxyisourate + H2O2
|
1.7.3.3
factor-independent urate hydroxylase
|
–
|
| |
BRENDA:
BR36977
KEGG:
R02106
SABIO-RK:
197
|
|
|
|
ATP + dAMP <=> ADP + dADP
|
2.7.4.11
(deoxy)adenylate kinase
2.7.4.13
(deoxy)nucleoside-phosphate kinase
2.7.4.3
adenylate kinase
2.7.4.4
nucleoside-phosphate kinase
|
–
–
–
–
|
| |
BRENDA:
BR48070
KEGG:
R01547
MetaCyc:
DEOXYADENYLATE-KINASE-RXN
SABIO-RK:
314
|
|
|
|
ppGpp + H2O <=> diphosphate + GDP
|
2.7.6.5
GTP diphosphokinase
3.1.7.2
guanosine-3',5'-bis(diphosphate) 3'-diphosphatase
3.6.1.41
bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
|
–
–
–
|
| |
BRENDA:
BR15976;
BS165348
KEGG:
R00336
MetaCyc:
PPGPPSYN-RXN
SABIO-RK:
78
|
|
|
|
2''-deoxyguanosine + ATP <=> H+ + dGMP + ADP
|
2.7.1.113
deoxyguanosine kinase
2.7.1.145
deoxynucleoside kinase
2.7.1.20
adenosine kinase
2.7.1.74
deoxycytidine kinase
2.7.1.76
2'-deoxyadenosine kinase
|
–
–
–
–
–
|
| |
BRENDA:
BR47726
KEGG:
R01967
MetaCyc:
DEOXYGUANOSINE-KINASE-RXN
SABIO-RK:
324
|
|
|
|
2''-deoxyguanosine + phosphate <=> guanine + 2-deoxy-alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.15
guanosine phosphorylase
2.4.2.4
thymidine phosphorylase
|
–
–
–
|
| |
BRENDA:
BS323156;
BS323208
KEGG:
R01969
MetaCyc:
DEOXYGUANPHOSPHOR-RXN
SABIO-RK:
360
|
|
|
|
5-aminoimidazole-4-carboxamide_ribonucleotide + formate + ATP <=> 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide + ADP + phosphate
|
6.3.4.23
formate---phosphoribosylaminoimidazolecarboxamide ligase
|
–
|
| |
BRENDA:
BR50732
KEGG:
R06975
MetaCyc:
RXN-10066
|
|
|
|
AMP + H2O <=> D-ribose_5-phosphate + adenine
|
3.2.2.1
purine nucleosidase
3.2.2.4
AMP nucleosidase
|
–
–
|
| |
BRENDA:
BR19230
KEGG:
R00182
MetaCyc:
AMP-NUCLEOSID-RXN
|
|
|
|
pyruvate + dGTP <=> phosphoenolpyruvate + dGDP + H+
|
2.7.1.40
pyruvate kinase
|
–
|
| |
BRENDA:
BS411977
KEGG:
R01858
MetaCyc:
RXN-14207
SABIO-RK:
284
|
|
|
|
ATP + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine <=> H+ + ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole
|
6.3.3.1
phosphoribosylformylglycinamidine cyclo-ligase
|
–
|
| |
BRENDA:
BR126
KEGG:
R04208
MetaCyc:
AIRS-RXN
|
|
|
|
H2O + 3''-phosphoadenylyl-sulfate <=> adenosine_3,5''-bisphosphate + H+ + sulfate
|
3.6.2.2
phosphoadenylylsulfatase
|
–
|
| |
BRENDA:
BR29533
KEGG:
R00507
MetaCyc:
PHOSPHOADENYLYLSULFATASE-RXN
|
|
|
|
guanosine + ATP <=> H+ + GMP + ADP
|
2.7.1.113
deoxyguanosine kinase
2.7.1.145
deoxynucleoside kinase
2.7.1.21
thymidine kinase
2.7.1.73
inosine kinase
2.7.1.76
2'-deoxyadenosine kinase
2.7.1.B20
|
–
–
–
–
–
–
|
| |
BRENDA:
BS353783
KEGG:
R01228
MetaCyc:
GUANOSINEKIN-RXN
|
|
|
|
XTP + H2O <=> H+ + XMP + diphosphate
|
3.6.1
3.6.1.66
XTP/dITP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
|
| |
BRENDA:
BR50710
KEGG:
R02720
MetaCyc:
RXN0-1603
SABIO-RK:
357
|
|
|
|
H+ + Urea + H2O <=> NH3 + CO2
|
3.5.1.5
urease
|
–
|
| |
BRENDA:
BR22694
KEGG:
R00131
MetaCyc:
UREASE-RXN
SABIO-RK:
289
|
|
|
|
ADP-ribose + H2O <=> AMP + D-ribose_5-phosphate + H+
|
3.6.1
3.6.1.13
ADP-ribose diphosphatase
3.6.1.21
ADP-sugar diphosphatase
3.6.1.53
Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
|
–
–
–
–
|
| |
BRENDA:
BR22753
KEGG:
R01054
MetaCyc:
RXN0-1441
|
|
|
|
NTP + AMP <=> NDP + ADP
|
2.7.4.10
nucleoside-triphosphate---adenylate kinase
|
–
|
| |
BRENDA:
BR47841
KEGG:
R00333
MetaCyc:
2.7.4.10-RXN
|
|
|
|
ATP + dIDP <=> ADP + dITP
|
2.7.4.6
nucleoside-diphosphate kinase
|
–
|
| |
KEGG:
R03530
MetaCyc:
RXN-14228
|
|
|
|
H+ + ATP + H2O <=> H+ + ADP + phosphate
|
2.7.1.1
hexokinase
2.7.1.2
glucokinase
2.7.11.24
mitogen-activated protein kinase
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.4.21.53
endopeptidase La
3.6.1
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.3
adenosinetriphosphatase
3.6.1.5
apyrase
3.6.1.6
nucleoside diphosphate phosphatase
3.6.1.8
ATP diphosphatase
3.6.2.1
adenylylsulfatase
3.6.4.10
non-chaperonin molecular chaperone ATPase
3.6.4.12
DNA helicase
3.6.4.13
RNA helicase
3.6.4.6
vesicle-fusing ATPase
3.6.4.7
peroxisome-assembly ATPase
3.6.4.B1
3.6.4.B10
3.6.4.B11
3.6.4.B4
3.6.4.B6
3.6.4.B7
3.6.4.B8
3.6.4.B9
5.6.1.1
microtubule-severing ATPase
5.6.1.7
chaperonin ATPase
5.6.1.8
myosin ATPase
7.1.2.1
P-type H+-exporting transporter
7.1.2.2
H+-transporting two-sector ATPase
7.2.2.1
Na+-transporting two-sector ATPase
7.6.2.1
P-type phospholipid transporter
7.6.2.2
ABC-type xenobiotic transporter
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR22769
KEGG:
R00086
MetaCyc:
3.6.3.6-RXN;
ABC-18-RXN;
ATPASE-RXN;
ATPSYN-RXN
SABIO-RK:
75
|
|
|
|
adenylosuccinate <=> fumarate + AMP
|
4.3.2.2
adenylosuccinate lyase
|
–
|
| |
BRENDA:
BR3432
KEGG:
R01083
MetaCyc:
AMPSYN-RXN
SABIO-RK:
306
|
|
|
|
D-ribose_5-phosphate + ATP <=> H+ + 5-phospho-alpha-D-ribose_1-diphosphate + AMP
|
2.7.6.1
ribose-phosphate diphosphokinase
|
–
|
| |
BRENDA:
BR47854
KEGG:
R01049
MetaCyc:
PRPPSYN-RXN
|
|
|
|
dGDP + ATP <=> dGTP + ADP
|
2.7.4.6
nucleoside-diphosphate kinase
|
–
|
| |
BRENDA:
BS358247
KEGG:
R01857
MetaCyc:
DGDPKIN-RXN
SABIO-RK:
183
|
|
|
|
H+ + AMP + H2O <=> IMP + NH3
|
3.5.4.17
adenosine-phosphate deaminase
3.5.4.4
adenosine deaminase
3.5.4.6
AMP deaminase
3.5.4.7
ADP deaminase
|
–
–
–
–
|
| |
BRENDA:
BR22743
KEGG:
R00181
MetaCyc:
AMP-DEAMINASE-RXN
SABIO-RK:
135
|
|
|
|
ATP + GTP <=> guanosine_3'-diphosphate_5'-triphosphate + AMP + H+
|
2.7.6.4
nucleotide diphosphokinase
2.7.6.5
GTP diphosphokinase
|
–
–
|
| |
BRENDA:
BR47857
KEGG:
R00429
MetaCyc:
GTPPYPHOSKIN-RXN
SABIO-RK:
236
|
|
|
|
dGTP + thioredoxin_disulfide + H2O <=> GTP + thioredoxin
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
| |
BRENDA:
BS287788
KEGG:
R02020
MetaCyc:
RXN-21263
SABIO-RK:
2052
|
|
|
|
(S)-ureidoglycine + H2O <=> (S)-ureidoglycolate + NH3
|
3.5.3.26
(S)-ureidoglycine aminohydrolase
|
–
|
| |
BRENDA:
BR50460
KEGG:
R05554
MetaCyc:
URUR-RXN
|
|
|
|
IMP + H2O <=> 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide
|
3.5.4.10
IMP cyclohydrolase
|
–
|
| |
BRENDA:
BR19263
KEGG:
R01127
MetaCyc:
IMPCYCLOHYDROLASE-RXN
SABIO-RK:
123
|
|
|
|
alpha-D-ribose_1-phosphate <=> D-ribose_5-phosphate
|
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.7
phosphopentomutase
|
–
–
|
| |
BRENDA:
BR23
KEGG:
R01057
MetaCyc:
PPENTOMUT-RXN
SABIO-RK:
13454
|
|
|
|
XMP + NH3 + ATP <=> GMP + AMP + diphosphate + H+
|
6.3.5.2
GMP synthase (glutamine-hydrolysing)
|
–
|
| |
BRENDA:
BR129
KEGG:
R01230
MetaCyc:
GMP-SYN-NH3-RXN
SABIO-RK:
191
|
|
