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phytosterol biosynthesis (plants)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
campesterol + NADP+ <=> H+ + crinosterol + NADPH 1.3.1
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4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD+ <=> avenastenone + NADH + CO2 1.1.1.418 plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
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30-oxoobtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + H2O + oxidized_[NADPH-hemoprotein_reductase] + H+ 1.14.14
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4alpha-formylergosta-7,24(241)-dien-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 3beta-hydroxyergosta-7,24(241)-dien-4alpha-carboxylate + ferricytochrome_b5 + H2O 1.14.18.11 plant 4alpha-monomethylsterol monooxygenase
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4alpha-formyl-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + ferricytochrome_b5 + H2O 1.14.18.10 plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase
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24-methylene_cholesterol + NADP+ <=> 5-dehydroepisterol + NADPH + H+ 1.3.1.21 7-dehydrocholesterol reductase
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24(28)-methylene_cycloartanol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + ferricytochrome_b5 + H2O 1.14.18.10 plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase
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cycloeucalenol <=> obtusifoliol 5.5.1.9 cycloeucalenol cycloisomerase
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cycloeucalenol + NADP+ <=> cycloeucalenone + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
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30-hydroxyobtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 30-oxoobtusifoliol + H2O + oxidized_[NADPH-hemoprotein_reductase] not assigned
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24(28)-methylene_lophenol <=> 4alpha-methyl-5alpha-ergosta-8,24-dien-3beta-ol 5.3.3.5 cholestenol Delta-isomerase
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24-methyldesmosterol + reduced_acceptor <=> ergosta-5-enol + acceptor 1.3
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H+ + Delta24-25-sitosterol + NADPH <=> sitosterol + NADP+ not assigned
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4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + H2O not assigned
 –
H+ + 24-methyldesmosterol + NADPH <=> campesterol + NADP+ 1.3
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episterol + O2 + ferricytochrome_b5 + H+ <=> 5-dehydroepisterol + H2O + ferricytochrome_b5 1.14.19.20 Delta7-sterol 5(6)-desaturase
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ergosta-5-enol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> brassicasterol + oxidized_[NADPH-hemoprotein_reductase] + H2O 1.14.19.41 sterol 22-desaturase
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24-ethylidenelophenol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + H2O not assigned
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avenasterol + NADP+ <=> avenastenone + NADPH + H+ 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
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3beta-hydroxyergosta-7,24(241)-dien-4alpha-carboxylate + NAD+ <=> Episterone + NADH + CO2 1.1.1.418 plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
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avenasterol + ferricytochrome_b5 + O2 + H+ <=> DELTA5,7-avenasterol + ferricytochrome_b5 + H2O 1.14.19.20 Delta7-sterol 5(6)-desaturase
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24(28)-methylene_lophenol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-(hydroxymethyl)ergosta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + H2O 1.14.18.11 plant 4alpha-monomethylsterol monooxygenase
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isofucosterol + NADP+ <=> DELTA5,7-avenasterol + NADPH + H+ 1.3.1.21 7-dehydrocholesterol reductase
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S-adenosyl-L-methionine + Cycloartenol <=> H+ + S-adenosyl-L-homocysteine + 24(28)-methylene_cycloartanol 2.1.1.142 cycloartenol 24-C-methyltransferase
2.1.1.41 sterol 24-C-methyltransferase
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sitosterol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> stigmasterol + oxidized_[NADPH-hemoprotein_reductase] + H2O 1.14.19.41 sterol 22-desaturase
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4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD+ <=> cycloeucalenone + NADH + CO2 1.1.1.418 plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
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4alpha-methyl-5alpha-ergosta-8,24-dien-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+ 1.3.1.70 Delta14-sterol reductase
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obtusifoliol + O2 + reduced_[NADPH-hemoprotein_reductase] <=> 30-hydroxyobtusifoliol + H2O + oxidized_[NADPH-hemoprotein_reductase] not assigned
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S-adenosyl-L-methionine + 24(28)-methylene_lophenol <=> H+ + 24-ethylidenelophenol + S-adenosyl-L-homocysteine 2.1.1.142 cycloartenol 24-C-methyltransferase
2.1.1.143 24-methylenesterol C-methyltransferase
2.1.1.41 sterol 24-C-methyltransferase
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–
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4alpha-(hydroxymethyl)ergosta-7,24(241)-dien-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-formylergosta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + H2O 1.14.18.11 plant 4alpha-monomethylsterol monooxygenase
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4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-formyl-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + ferricytochrome_b5 + H2O 1.14.18.10 plant 4,4-dimethylsterol C-4alpha-methyl-monooxygenase
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24-methylene_cholesterol <=> 24-methyldesmosterol not assigned
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isofucosterol <=> Delta24-25-sitosterol not assigned
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4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + H2O not assigned
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Episterone + NADPH + H+ <=> episterol + NADP+ 1.1.1
1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase
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Visualization of the pathway