Copied!

Pathway Search



palmitate biosynthesis (type II fatty acid synthase)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
decanoyl-[acyl-carrier_protein] + NAD+ <=> (2E)-dec-2-enoyl-[acp] + NADH + H+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)

laurate + CoA + ATP <=> lauroyl-CoA + diphosphate + AMP 1.13.12.7 firefly luciferase
6.2.1.11 biotin---CoA ligase
6.2.1.2 medium-chain acyl-CoA ligase
6.2.1.3 long-chain-fatty-acid---CoA ligase
6.2.1.B3





(3R)-3-hydroxyoctanoyl-[acyl-carrier_protein] <=> 2-octenoyl-[acyl-carrier_protein] + H2O 2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
4.2.1
4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase





fatty_acid + CoA + ATP <=> stearoyl-CoA + AMP + diphosphate 1.13.12.7 firefly luciferase
6.2.1.12 4-coumarate---CoA ligase
6.2.1.3 long-chain-fatty-acid---CoA ligase
6.2.1.30 phenylacetate---CoA ligase
6.2.1.B3





palmitoyl-[acyl-carrier_protein] + H2O <=> fatty_acid + [acyl-carrier_protein] + H+ 2.3.1.85 fatty-acid synthase system
3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase
3.1.2.21 dodecanoyl-[acyl-carrier-protein] hydrolase



octanoyl-[acyl-carrier_protein] + NAD+ <=> 2-octenoyl-[acyl-carrier_protein] + NADH + H+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1


dodecanoyl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + H+ <=> 3-oxotetradecanoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein] 2.3.1
2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





(3R)-3-hydroxymyristoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxotetradecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





(3R)-3-hydroxybutanoyl-[acyl-carrier_protein] <=> H2O + trans-but-2-enoyl-[acyl-carrier_protein] 4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase

(3R)-3-hydroxyhexanoyl-[acp] <=> trans-Hex-2-enoyl-[acp] + H2O 4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase

(3R)-3-hydroxymyristoyl-[acyl-carrier_protein] <=> trans-Tetradec-2-enoyl-[acp] + H2O 2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system
4.2.1
4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase





palmitoyl-[acyl-carrier_protein] + NAD+ <=> trans-Hexadec-2-enoyl-[acp] + NADH + H+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1


hexanoyl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + H+ <=> 3-oxooctanoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein] 2.3.1
2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





(3R)-3-hydroxydecanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxodecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





(3R)-3-hydroxyhexadecanoyl-[acp] + NADP+ <=> 3-oxohexadecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase

(3R)-3-hydroxyhexadecanoyl-[acp] <=> H2O + trans-Hexadec-2-enoyl-[acp] 4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase

(3R)-3-hydroxydecanoyl-[acyl-carrier_protein] <=> (2E)-dec-2-enoyl-[acp] + H2O 4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase

butyryl-[acyl-carrier_protein] + NAD+ <=> trans-but-2-enoyl-[acyl-carrier_protein] + NADH + H+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1


octanoyl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + H+ <=> 3-oxodecanoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein] 2.3.1
2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





decanoyl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + H+ <=> 3-oxododecanoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein] 2.3.1
2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





butyryl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + H+ <=> 3-oxohexanoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein] 2.3.1
2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





(3R)-3-hydroxyoctanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxooctanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





(3R)-3-hydroxydodecanoyl-[acp] <=> dodecenoyl-[Staphylococcus_aureus_acyl_carrier_protein] + H2O 4.2.1.59 3-hydroxyacyl-[acyl-carrier-protein] dehydratase

dodecanoyl-[acyl-carrier_protein] + NAD+ <=> dodecenoyl-[Staphylococcus_aureus_acyl_carrier_protein] + NADH + H+ 1.3.1.38 trans-2-enoyl-CoA reductase (NADPH)
1.3.1.39 enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1




tetradecanoyl-[acyl-carrier_protein] + NAD+ <=> trans-Tetradec-2-enoyl-[acp] + NADH + H+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1


(3R)-3-hydroxyhexanoyl-[acp] + NADP+ <=> 3-oxohexanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase

(3R)-3-hydroxydodecanoyl-[acp] + NADP+ <=> 3-oxododecanoyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase

(3R)-3-hydroxybutanoyl-[acyl-carrier_protein] + NADP+ <=> acetoacetyl-[acyl-carrier_protein] + NADPH + H+ 1.1.1
1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





hexanoyl-[acyl-carrier_protein] + NAD+ <=> trans-Hex-2-enoyl-[acp] + NADH + H+ 1.3.1.9 enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1


tetradecanoyl-[acyl-carrier_protein] + malonyl-[acyl-carrier_protein] + H+ <=> 3-oxohexadecanoyl-[acyl-carrier_protein] + CO2 + [acyl-carrier_protein] 2.3.1
2.3.1.179 beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.41 beta-ketoacyl-[acyl-carrier-protein] synthase I
2.3.1.85 fatty-acid synthase system
2.3.1.86 fatty-acyl-CoA synthase system





dodecanoyl-[acyl-carrier_protein] + H2O <=> [acyl-carrier_protein] + laurate + H+ 3.1.2.14 oleoyl-[acyl-carrier-protein] hydrolase
3.1.2.21 dodecanoyl-[acyl-carrier-protein] hydrolase


Visualization of the pathway