|
|
4-aminobutanoate + 2-oxoglutarate <=> succinate_semialdehyde + L-glutamate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.22
(S)-3-amino-2-methylpropionate transaminase
2.6.1.29
diamine transaminase
2.6.1.48
5-aminovalerate transaminase
|
–
–
–
–
–
|
| |
BRENDA:
BR47437
KEGG:
R01648
MetaCyc:
GABATRANSAM-RXN
SABIO-RK:
1785
|
|
|
|
(R)-nicotine + H2O + acceptor <=> 6-hydroxy-D-nicotine + reduced_acceptor
|
1.5.99.4
nicotine dehydrogenase
|
–
|
| |
BRENDA:
BS370749
MetaCyc:
R161-RXN
|
|
|
|
H+ + 2,6-Dihydroxypyridine + O2 + NADH <=> H2O + NAD+ + 2,3,6-Trihydroxypyridine
|
1.14.13.10
2,6-dihydroxypyridine 3-monooxygenase
|
–
|
| |
BRENDA:
BR40437
KEGG:
R04130
MetaCyc:
1.14.13.10-RXN
SABIO-RK:
3851
|
|
|
|
6-hydroxy-L-nicotine + O2 <=> 6-hydroxy-N-methylmyosmine + H2O2
|
1.5.3.5
(S)-6-hydroxynicotine oxidase
|
–
|
| |
BRENDA:
BR51483
KEGG:
R11048
MetaCyc:
RXN-16526
|
|
|
|
1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O + acceptor <=> 1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one + reduced_acceptor
|
1.5.99.14
6-hydroxypseudooxynicotine dehydrogenase
|
–
|
| |
BRENDA:
BR50155
KEGG:
R07514
MetaCyc:
R162-RXN
|
|
|
|
6-hydroxy-D-nicotine + O2 <=> 6-hydroxy-N-methylmyosmine + H2O2
|
1.5.3.6
(R)-6-hydroxynicotine oxidase
|
–
|
| |
BRENDA:
BR51485
KEGG:
R11050
MetaCyc:
RXN-16528
|
|
|
|
1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O <=> 2,6-Dihydroxypyridine + 4-methylaminobutanoate + H+
|
3.7.1.19
2,6-dihydroxypseudooxynicotine hydrolase
|
–
|
| |
BRENDA:
BR50199
KEGG:
R07515
MetaCyc:
R181-RXN
SABIO-RK:
13043
|
|
|
|
4-methylaminobutanoate + O2 + H2O <=> 4-aminobutanoate + formaldehyde + H2O2
|
1.5.3.19
4-methylaminobutanoate oxidase (formaldehyde-forming)
|
–
|
| |
BRENDA:
BR50152
KEGG:
R10102
MetaCyc:
RXN-13067
|
|
|
|
2,3,6-Trihydroxypyridine + acceptor <=> nicotine_blue + reduced_acceptor
|
not assigned
|
–
|
| |
MetaCyc:
RXN-13068
|
|
|
|
2,3,6-Trihydroxypyridine <=> 2,3,6-Trihydroxypyridine + H+
|
not assigned
|
–
|
| |
MetaCyc:
RXN-13070
|
|
|
|
Nicotine + H2O + oxidized_pseudoazurin <=> 6-hydroxy-L-nicotine + reduced_pseudoazurin + H+
|
1.5.99.4
nicotine dehydrogenase
|
–
|
| |
MetaCyc:
NICOTINE-DEHYDROGENASE-RXN
|
|
|
|
2,3,6-Trihydroxypyridine + H2O <=> 2-Oxoglutaramate
|
not assigned
|
–
|
| |
MetaCyc:
RXN-13071
|
|
|
|
nicotine_blue_leuco_form + NADP+ <=> nicotine_blue + NADPH + H+
|
1.1.1.328
nicotine blue oxidoreductase
|
–
|
| |
BRENDA:
BR50137
KEGG:
R10132
MetaCyc:
RXN-13069
|
|
|
|
4-methylaminobutanoate + H2O + O2 <=> succinate_semialdehyde + methylamine + H2O2
|
1.5.3.21
4-methylaminobutanoate oxidase (methylamine-forming)
|
–
|
| |
BRENDA:
BR50154
KEGG:
R10101
MetaCyc:
RXN-13065
|
|
|
|
6-hydroxy-N-methylmyosmine + H2O <=> 1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one
|
1.5.3.5
(S)-6-hydroxynicotine oxidase
1.5.3.6
(R)-6-hydroxynicotine oxidase
|
–
–
|
| |
BRENDA:
BR51484
KEGG:
R11049
MetaCyc:
RXN-16527
|
|
|
|
2-Oxoglutaramate + H2O <=> 2-oxoglutarate + NH3
|
3.5.1.111
2-oxoglutaramate amidase
3.5.1.3
omega-amidase
3.5.1.36
N-methyl-2-oxoglutaramate hydrolase
|
–
–
–
|
| |
BRENDA:
BR50321
KEGG:
R00269
MetaCyc:
RXN-13072
SABIO-RK:
771
|
|
|
|
succinate_semialdehyde + NADP+ + H2O <=> NADPH + succinate + H+
|
1.1.1.21
aldose reductase
1.2.1.16
succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.79
succinate-semialdehyde dehydrogenase (NADP+)
|
–
–
–
–
–
|
| |
BRENDA:
BR29388
KEGG:
R00714
MetaCyc:
RXN0-5293;
SUCCSEMIALDDEHYDROG-RXN
SABIO-RK:
1086
|
|
