|
|
(6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate <=> leukotriene_A4 + H2O
|
1.13.11.34
arachidonate 5-lipoxygenase
|
–
|
| |
BRENDA:
BR49526
KEGG:
R03058
MetaCyc:
RXN-8647
|
|
|
|
leukotriene_D4 + H2O <=> glycine + leukotriene_E4
|
2.3.2
3.4.13.19
membrane dipeptidase
|
–
–
|
| |
KEGG:
R05055
MetaCyc:
RXN66-337
|
|
|
|
O2 + arachidonic_acid <=> (6E,8Z,11Z,14Z)-(5S)-hydroperoxyicosa-6,8,11,14-tetraenoate
|
1.13.11.34
arachidonate 5-lipoxygenase
|
–
|
| |
BRENDA:
BR49525
KEGG:
R01595
MetaCyc:
ARACHIDONATE-5-LIPOXYGENASE-RXN
SABIO-RK:
1744
|
|
|
|
leukotriene_C4 <=> leukotriene_A4 + glutathione
|
4.4.1.20
leukotriene-C4 synthase
|
–
|
| |
BRENDA:
BR48007
KEGG:
R03059
MetaCyc:
LEUKOTRIENE-C4-SYNTHASE-RXN
SABIO-RK:
8569
|
|
|
|
leukotriene_A4 + H2O <=> leukotriene_B4
|
3.3.2.6
leukotriene-A4 hydrolase
|
–
|
| |
BRENDA:
BR48209
KEGG:
R03057
MetaCyc:
LEUKOTRIENE-A4-HYDROLASE-RXN
SABIO-RK:
2902
|
|
|
|
leukotriene_C4 + proteinogenic_amino_acid <=> gamma-glutamyl-L-alanine + leukotriene_D4
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
| |
MetaCyc:
RXN66-336
|
|
