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icosapentaenoate biosynthesis I (lower eukaryotes)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
stearidonoyl-CoA + glycerolipid <=> [glycerolipid]-stearidonate + CoA 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase
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(3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA <=> (2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + H2O 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
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[glycerolipid]-(8Z,11Z,14Z,17Z)-icosatetraenoate + O2 + ferricytochrome_b5 + H+ <=> [glycerolipid]-(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + H2O + ferricytochrome_b5 1.14.19.30 acyl-lipid (8-3)-desaturase
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(8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + glycerolipid <=> [glycerolipid]-(8Z,11Z,14Z,17Z)-icosatetraenoate + CoA 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase
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(8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + NADPH + H+ <=> (3R,8Z,11Z,14Z,17Z)-3-hydroxyicosatetraenoyl-CoA + NADP+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
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malonyl-CoA + stearidonoyl-CoA + H+ <=> (8Z,11Z,14Z,17Z)-3-oxoicosatetraenoyl-CoA + CoA + CO2 2.3.1
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(2E,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA + reduced_acceptor <=> (8Z,11Z,14Z,17Z)-icosa-8,11,14,17-tetraenoyl-CoA + acceptor 1.3.1.93 very-long-chain enoyl-CoA reductase
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[glycerolipid]-alpha-linolenate + O2 + ferricytochrome_b5 + H+ <=> [glycerolipid]-stearidonate + ferricytochrome_b5 + H2O 1.14.19.47 acyl-lipid (9-3)-desaturase
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