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gluconeogenesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
oxaloacetate + H+ <=> pyruvate + CO2 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
4.1.1.112 oxaloacetate decarboxylase
4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
4.1.2.52 4-hydroxy-2-oxoheptanedioate aldolase
4.1.3.16 4-hydroxy-2-oxoglutarate aldolase
4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate aldolase
4.1.3.39 4-hydroxy-2-oxovalerate aldolase
4.1.3.42 (4S)-4-hydroxy-2-oxoglutarate aldolase
4.1.3.43 4-hydroxy-2-oxohexanoate aldolase
4.4.1.1 cystathionine gamma-lyase
7.2.4.2 oxaloacetate decarboxylase (Na+ extruding)












(S)-malate + NAD+ <=> pyruvate + CO2 + NADH 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.39 malate dehydrogenase (decarboxylating)
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.85 3-isopropylmalate dehydrogenase
1.3.1.7 meso-tartrate dehydrogenase





(S)-malate + NADP+ <=> pyruvate + CO2 + NADPH 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.39 malate dehydrogenase (decarboxylating)
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.85 3-isopropylmalate dehydrogenase




oxaloacetate + GTP <=> CO2 + phosphoenolpyruvate + GDP 4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
4.1.1.49 phosphoenolpyruvate carboxykinase (ATP)


H2O + pyruvate + ATP <=> H+ + phosphate + phosphoenolpyruvate + AMP 2.7.1.40 pyruvate kinase
2.7.9.2 pyruvate, water dikinase


oxaloacetate + ATP <=> CO2 + phosphoenolpyruvate + ADP 4.1.1.31 phosphoenolpyruvate carboxylase
4.1.1.38 phosphoenolpyruvate carboxykinase (diphosphate)
4.1.1.49 phosphoenolpyruvate carboxykinase (ATP)



phosphoenolpyruvate + CO2 <=> phosphate + oxaloacetate 4.1.1.31 phosphoenolpyruvate carboxylase

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