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docosahexaenoate biosynthesis IV (4-desaturase, mammals)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + reduced_acceptor <=> docosapentaenoyl-CoA + acceptor 1.3.1.93 very-long-chain enoyl-CoA reductase
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malonyl-CoA + eicosapentaenoyl-CoA + H+ <=> (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + CoA + CO2 2.3.1
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docosahexaenoyl-CoA + glycerolipid <=> [glycerolipid]-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + CoA 2.3.1
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(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA <=> (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
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(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA + NADP+ <=> (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
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docosapentaenoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> docosahexaenoyl-CoA + H2O + ferricytochrome_b5 1.14.19
1.14.19.44 acyl-CoA (8-3)-desaturase
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