Copied!

Pathway Search


docosahexaenoate biosynthesis I (lower eukaryotes)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + reduced_acceptor <=> docosapentaenoyl-CoA + acceptor 1.3.1.93 very-long-chain enoyl-CoA reductase
–
docosapentaenoyl-CoA + glycerolipid <=> [glycerolipid](7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + CoA 2.3.1
–
malonyl-CoA + eicosapentaenoyl-CoA + H+ <=> (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + CoA + CO2 2.3.1
–
[glycerolipid](7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + O2 + ferricytochrome_b5 + H+ <=> [glycerolipid]-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + ferricytochrome_b5 + H2O 1.14.19.31 acyl-lipid (7-3)-desaturase
–
(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA <=> (2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + H2O 4.2.1.134 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
–
(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA + NADP+ <=> (5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA + NADPH + H+ 1.1.1.330 very-long-chain 3-oxoacyl-CoA reductase
–
[glycerolipid]-(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate + CoA <=> eicosapentaenoyl-CoA + glycerolipid 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase
–

Visualization of the pathway