|
|
S-adenosyl-L-methionine + L-histidine-[translation_elongation_factor_2] <=> 2-(3-carboxy-3-aminopropyl)-L-histidine-[translation_elongation_factor_2] + S-methyl-5''-thioadenosine + H+
|
2.5.1.108
2-(3-amino-3-carboxypropyl)histidine synthase
|
–
|
|
BRENDA:
BR50668
KEGG:
R10455
MetaCyc:
RXN-11371
|
|
|
|
diphthine + NH3 + ATP <=> H+ + diphthamide-[translation_elongation_factor_2] + AMP + diphosphate
|
6.3.1.14
diphthine---ammonia ligase
|
–
|
|
BRENDA:
BR115
KEGG:
R03613
MetaCyc:
DIPHTINE--AMMONIA-LIGASE-RXN
|
|
|
|
S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine-[translation_elongation_factor_2] <=> diphthine_methyl_ester-[translation_elongation_factor_2] + S-adenosyl-L-homocysteine + H+
|
2.1.1.314
diphthine methyl ester synthase
|
–
|
|
BRENDA:
BR51302
KEGG:
R11165
MetaCyc:
RXN-15775
|
|
|
|
diphthine_methyl_ester-[translation_elongation_factor_2] + H2O <=> diphthine + methanol + H+
|
3.1.1.97
methylated diphthine methylhydrolase
|
–
|
|
BRENDA:
BR51191
KEGG:
R11166
MetaCyc:
RXN-15776
|
|