|
|
L-serine + tetrahydrofolate <=> glycine + 5,10-methylenetetrahydrofolate + H2O
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
| |
BRENDA:
BR40573
KEGG:
R00945
MetaCyc:
GLYOHMETRANS-RXN
SABIO-RK:
95
|
|
|
|
5,10-methylenetetrahydrofolate + dUMP <=> dTMP + 7,8-dihydrofolate
|
2.1.1.45
thymidylate synthase
|
–
|
| |
BRENDA:
BR43900;
BS319728
KEGG:
R02101
MetaCyc:
THYMIDYLATESYN-RXN
SABIO-RK:
88
|
|
|
|
tetrahydrofolate + NADP+ <=> 7,8-dihydrofolate + NADPH + H+
|
1.5.1.3
dihydrofolate reductase
1.5.1.33
pteridine reductase
1.5.1.34
6,7-dihydropteridine reductase
1.5.1.50
dihydromonapterin reductase
|
–
–
–
–
|
| |
BRENDA:
BR36900
KEGG:
R00939
MetaCyc:
DIHYDROFOLATEREDUCT-RXN;
RXN-19329
|
|
