|
|
Maleate <=> fumarate
|
5.2.1.1
maleate isomerase
|
–
|
| |
BRENDA:
BR208
KEGG:
R01087
MetaCyc:
MALEATE-ISOMERASE-RXN
|
|
|
|
succinyl-CoA + acetoacetate <=> succinate + acetoacetyl-CoA
|
2.8.3.18
succinyl-CoA:acetate CoA-transferase
2.8.3.5
3-oxoacid CoA-transferase
|
–
–
|
| |
BRENDA:
BS360598
KEGG:
R00410
MetaCyc:
RXNI-2
SABIO-RK:
867
|
|
|
|
(S)-malate + acceptor <=> oxaloacetate + reduced_acceptor
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
| |
BRENDA:
BS402298
|
|
|
|
isocitrate <=> glyoxylate + succinate
|
4.1.3.1
isocitrate lyase
|
–
|
| |
BRENDA:
BR3364;
BS380792
KEGG:
R00479
MetaCyc:
ISOCIT-CLEAV-RXN
SABIO-RK:
14841
|
|
|
|
isocitrate + NADP+ <=> 2-oxoglutarate + CO2 + NADPH
|
1.1.1.286
isocitrate---homoisocitrate dehydrogenase
1.1.1.41
isocitrate dehydrogenase (NAD+)
1.1.1.42
isocitrate dehydrogenase (NADP+)
|
–
–
–
|
| |
BRENDA:
BR29305;
BS370920
KEGG:
R00267
MetaCyc:
ISOCITDEH-RXN
SABIO-RK:
14842;
15247;
269
|
|
|
|
(S)-malate + a_quinone <=> oxaloacetate + a_quinol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
| |
BRENDA:
BR49054;
BS421758
KEGG:
R00361
|
|
|
|
acetyl-CoA + citrate <=> acetate + (3S)-citryl-CoA
|
2.8.3.10
citrate CoA-transferase
|
–
|
| |
BRENDA:
BR47921
KEGG:
R01323
MetaCyc:
2.8.3.10-RXN
|
|
|
|
(S)-malate + NADP+ <=> H+ + NADPH + oxaloacetate
|
1.1.1.299
malate dehydrogenase [NAD(P)+]
1.1.1.37
malate dehydrogenase
1.1.1.375
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.81
hydroxypyruvate reductase
1.1.1.82
malate dehydrogenase (NADP+)
|
–
–
–
–
–
–
|
| |
BRENDA:
BR29342;
BS188648
KEGG:
R00343
MetaCyc:
MALATE-DEHYDROGENASE-NADP+-RXN;
RXN-10813
SABIO-RK:
143
|
|
|
|
citrate <=> cis-aconitate + H2O
|
4.2.1.117
2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.3
aconitate hydratase
|
–
–
|
| |
BRENDA:
BR419
KEGG:
R01325
MetaCyc:
ACONITATEDEHYDR-RXN
SABIO-RK:
268
|
|
|
|
(3S)-citryl-CoA <=> oxaloacetate + acetyl-CoA
|
4.1.3.34
citryl-CoA lyase
|
–
|
| |
BRENDA:
BR3376
KEGG:
R00354
MetaCyc:
RXN-7929
|
|
|
|
oxaloacetate + acetyl-CoA + phosphate + ADP <=> citrate + CoA + ATP
|
2.3.3.8
ATP citrate synthase
|
–
|
| |
BRENDA:
BR44130
KEGG:
R00352
MetaCyc:
ATP-CITRATE-PRO-S--LYASE-RXN
SABIO-RK:
266
|
|
|
|
succinate + FAD <=> fumarate + FADH2
|
1.3.1.6
fumarate reductase (NADH)
1.3.5.1
succinate dehydrogenase
|
–
–
|
| |
BRENDA:
BS413615
KEGG:
R00408
SABIO-RK:
865
|
|
|
|
(S)-malate <=> fumarate + H2O
|
4.2.1.2
fumarate hydratase
4.2.1.34
(S)-2-methylmalate dehydratase
|
–
–
|
| |
BRENDA:
BR3389
KEGG:
R01082
MetaCyc:
FUMHYDR-RXN
SABIO-RK:
256
|
|
|
|
2-oxoglutarate + CoA + oxidized_ferredoxin <=> succinyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.2.7.11
2-oxoacid oxidoreductase (ferredoxin)
1.2.7.3
2-oxoglutarate synthase
|
–
–
|
| |
BRENDA:
BR50765
KEGG:
R01197
MetaCyc:
2-OXOGLUTARATE-SYNTHASE-RXN
|
|
|
|
succinyl-CoA + acetate <=> succinate + acetyl-CoA
|
2.8.3.1
propionate CoA-transferase
2.8.3.18
succinyl-CoA:acetate CoA-transferase
2.8.3.8
acetate CoA-transferase
|
–
–
–
|
| |
BRENDA:
BR50544
KEGG:
R10343
MetaCyc:
RXN-8807
SABIO-RK:
14383
|
|
|
|
isocitrate + NAD+ <=> 2-oxoglutarate + CO2 + NADH
|
1.1.1.286
isocitrate---homoisocitrate dehydrogenase
1.1.1.41
isocitrate dehydrogenase (NAD+)
1.1.1.42
isocitrate dehydrogenase (NADP+)
1.1.1.87
homoisocitrate dehydrogenase
|
–
–
–
–
|
| |
BRENDA:
BR29304;
BS371189
KEGG:
R00709
MetaCyc:
ISOCITRATE-DEHYDROGENASE-NAD+-RXN
SABIO-RK:
15068;
270
|
|
|
|
acetyl-CoA + H2O + oxaloacetate <=> citrate + CoA + H+
|
2.3.3.1
citrate (Si)-synthase
2.3.3.14
homocitrate synthase
2.3.3.16
citrate synthase (unknown stereospecificity)
2.3.3.3
citrate (Re)-synthase
|
–
–
–
–
|
| |
BRENDA:
BR44118
KEGG:
R00351
MetaCyc:
CITSYN-RXN;
RXN-14905
SABIO-RK:
267
|
|
|
|
acetyl-CoA + H2O + glyoxylate <=> H+ + (S)-malate + CoA
|
2.3.3.9
malate synthase
4.1.3.1
isocitrate lyase
|
–
–
|
| |
BRENDA:
BR47548;
BS381320
KEGG:
R00472
MetaCyc:
MALSYN-RXN
SABIO-RK:
152
|
|
|
|
succinate + CoA + ATP <=> succinyl-CoA + ADP + phosphate
|
6.2.1.13
acetate---CoA ligase (ADP-forming)
6.2.1.4
succinate---CoA ligase (GDP-forming)
6.2.1.5
succinate---CoA ligase (ADP-forming)
|
–
–
–
|
| |
BRENDA:
BR88
KEGG:
R00405
MetaCyc:
SUCCCOASYN-RXN
SABIO-RK:
260
|
|
|
|
citrate + CoA + ATP <=> (3S)-citryl-CoA + ADP + phosphate
|
6.2.1.18
citrate---CoA ligase
|
–
|
| |
BRENDA:
BR69
KEGG:
R01322
MetaCyc:
CITRATE--COA-LIGASE-RXN
|
|
|
|
succinate + a_quinone <=> fumarate + a_quinol
|
1.3.5.1
succinate dehydrogenase
1.3.5.4
fumarate reductase (quinol)
|
–
–
|
| |
BRENDA:
BR49374
KEGG:
R02164
|
|
|
|
succinate + GTP + CoA <=> succinyl-CoA + GDP + phosphate
|
6.2.1.4
succinate---CoA ligase (GDP-forming)
|
–
|
| |
BRENDA:
BR87
KEGG:
R00432
MetaCyc:
SUCCINATE--COA-LIGASE-GDP-FORMING-RXN
SABIO-RK:
259
|
|
|
|
(S)-malate + NAD+ <=> oxaloacetate + NADH + H+
|
1.1.1.28
D-lactate dehydrogenase
1.1.1.299
malate dehydrogenase [NAD(P)+]
1.1.1.337
L-2-hydroxycarboxylate dehydrogenase (NAD+)
1.1.1.37
malate dehydrogenase
1.1.1.375
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.38
malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.81
hydroxypyruvate reductase
1.1.1.82
malate dehydrogenase (NADP+)
1.1.1.85
3-isopropylmalate dehydrogenase
1.1.1.95
phosphoglycerate dehydrogenase
1.1.1.96
diiodophenylpyruvate reductase
|
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR29300;
BS188027
KEGG:
R00342
MetaCyc:
MALATE-DEH-RXN;
RXN-10813_WOP
|
|
