|
|
22-hydroxy-3-oxochol-4-en-24-oyl-CoA <=> 3-oxochol-4,22-dien-24-oyl-CoA + H2O
|
4.2.1
|
–
|
| |
MetaCyc:
RXN-12708
|
|
|
|
3-oxo-23,24-bisnorchol-4-en-22-oic_acid-CoA + acceptor <=> 3-oxo-23,24-bisnorchol-4,17(20)-dien-22-oyl-CoA + reduced_acceptor
|
1.3.99
|
–
|
| |
MetaCyc:
RXN-12743
|
|
|
|
24-hydroxy-3-oxocholest-4-en-26-oyl-CoA + NAD+ <=> 3,24-dioxocholest-4-en-26-oyl-CoA + NADH + H+
|
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
|
| |
MetaCyc:
RXN-12705
|
|
|
|
3-oxochol-4-en-24-oyl-CoA + acceptor <=> 3-oxochol-4,22-dien-24-oyl-CoA + reduced_acceptor
|
1.3.99
|
–
|
| |
MetaCyc:
RXN-12707
|
|
|
|
3-oxochol-4-en-24-oyl-CoA + propionyl-CoA <=> 3,24-dioxocholest-4-en-26-oyl-CoA + CoA
|
2.3.1.176
propanoyl-CoA C-acyltransferase
|
–
|
| |
MetaCyc:
RXN-12706
|
|
|
|
22-hydroxy-3-oxochol-4-en-24-oyl-CoA + NAD+ <=> 3,22-dioxochol-4-en-24-oyl-CoA + NADH + H+
|
1.1.1
|
–
|
| |
MetaCyc:
RXN-12709
|
|
|
|
17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA <=> 4-androstene-3,17-dione + propionyl-CoA
|
2.3.1
|
–
|
| |
MetaCyc:
RXN-12745
|
|
|
|
(25S)-3-oxocholest-4-en-26-oate + ATP + CoA <=> (25S)-3-oxocholest-4-en-26-oyl-CoA + AMP + diphosphate
|
6.2.1.42
3-oxocholest-4-en-26-oate---CoA ligase
|
–
|
| |
BRENDA:
BR51068
KEGG:
R10770
MetaCyc:
RXN-12702
|
|
|
|
17-hydroxy-3-oxo-4-pregnane-20-carboxyl-CoA <=> 3-oxo-23,24-bisnorchol-4,17(20)-dien-22-oyl-CoA + H2O
|
4.2.1
|
–
|
| |
MetaCyc:
RXN-12744
|
|
|
|
24-hydroxy-3-oxocholest-4-en-26-oyl-CoA <=> 3-oxocholest-4,24-dien-26-oyl-CoA + H2O
|
4.2.1
|
–
|
| |
MetaCyc:
RXN-12704
|
|
|
|
(25S)-26-hydroxycholest-4-en-3-one + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> (25S)-26-oxocholest-4-en-3-one + oxidized_ferredoxin + H2O
|
1.14.15.29
cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
|
–
|
| |
BRENDA:
BR51665
KEGG:
R11355
MetaCyc:
RXN-12850
|
|
|
|
(25S)-26-oxocholest-4-en-3-one + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> (25S)-3-oxocholest-4-en-26-oate + oxidized_ferredoxin + H2O
|
1.14.15.29
cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
|
–
|
| |
KEGG:
R11356
MetaCyc:
RXN-12849
|
|
|
|
O2 + cholesterol <=> 5-Cholesten-3-one + H2O2
|
1.1.3.6
cholesterol oxidase
|
–
|
| |
BRENDA:
BR29364
MetaCyc:
RXN-12778
|
|
|
|
3-oxo-23,24-bisnorchol-4-en-22-oic_acid-CoA + acetyl-CoA <=> 3,22-dioxochol-4-en-24-oyl-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
|
| |
MetaCyc:
RXN-12710
|
|
|
|
5-Cholesten-3-one <=> cholest-4-en-3-one
|
5.3.3.1
steroid Delta-isomerase
|
–
|
| |
BRENDA:
BS1075
MetaCyc:
RXN-12694
|
|
|
|
(25S)-3-oxocholest-4-en-26-oyl-CoA + acceptor <=> 3-oxocholest-4,24-dien-26-oyl-CoA + reduced_acceptor
|
1.3.99
|
–
|
| |
MetaCyc:
RXN-12703
|
|
|
|
cholest-4-en-3-one + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> (25S)-26-hydroxycholest-4-en-3-one + H2O + oxidized_ferredoxin
|
1.14.15.29
cholest-4-en-3-one 26-monooxygenase [(25S)-3-oxocholest-4-en-26-oate forming]
|
–
|
| |
BRENDA:
BR51664
KEGG:
R09859
MetaCyc:
RXN-12848
|
|
