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aurachin A, B, C and D biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
4-[(2E,6E,10E)-3,7-dimethyldodeca-2,6,10-trien-1-yl]-2-methyl-1-oxo-3,4,4a,8a-tetrahydro-1lambda5-quinoline-3,4-diol + NADP+ <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide + NADPH + H+ not assigned
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anthranilate + CoA + ATP <=> 2-aminobenzoyl-CoA + AMP + diphosphate 6.2.1.2 medium-chain acyl-CoA ligase
6.2.1.25 benzoate---CoA ligase
6.2.1.32 anthranilate---CoA ligase
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–
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4-[(2E,6E,10E)-3,7-dimethyldodeca-2,6,10-trien-1-yl]-2-methyl-1-oxo-3,4,4a,8a-tetrahydro-1lambda5-quinoline-3,4-diol <=> aurachin_B + H2O 1.1.1.394 aurachin B dehydrogenase
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aurachin_B + O2 + NADPH + H+ <=> Aurachin_B_epoxide + NADP+ + H2O 1.14.13
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2-aminobenzoyl-CoA + malonyl-CoA + H+ <=> 4-hydroxy-2-methylquinoline + CoA + CO2 2.3.1
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Aurachin_B_epoxide <=> aurachin_A not assigned
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aurachin_C + O2 + NADPH + H+ <=> 2-hydroxy-1a-methyl-7a-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one + NADP+ + H2O 1.14.13.222 aurachin C monooxygenase/isomerase
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4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide not assigned
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aurachin_D + O2 + NADPH + H+ <=> aurachin_C + H2O + NADP+ 1.14.13
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2-hydroxy-1a-methyl-7a-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)-1a,2-dihydrooxireno[2,3-b]quinolin-7(7aH)-one <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide 1.14.13.222 aurachin C monooxygenase/isomerase
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(2E,6E)-farnesyl_diphosphate + 4-hydroxy-2-methylquinoline <=> aurachin_D + diphosphate 2.5.1
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