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actinomycin D biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
3-hydroxy-4-methylanthranilyl-adenylate + holo-[AcmD_acyl-carrier_protein] <=> 3-hydroxy-4-methyl-anthranilyl-[AcmD_acyl-carrier_protein] + AMP + H+ not assigned

3-hydroxy-4-methyl-anthranilate_pentapeptide_lactone + O2 <=> actinomycin_D + H2O 1.10.3.4 o-aminophenol oxidase

4-methyl-3-hydroxyanthranilic_acid + ATP + H+ <=> 3-hydroxy-4-methylanthranilyl-adenylate + diphosphate 2.7.7.97 3-hydroxy-4-methylanthranilate adenylyltransferase

3-hydroxy-4-methyl-anthranilyl-[AcmD_acyl-carrier_protein] + L-threonine + L-valine + ATP <=> 3-hydroxy-4-methyl-anthranilyl-L-threonyl-D-valyl-[AcmD_acyl-carrier_protein] + ADP + phosphate + H+ 6.3.1

S-adenosyl-L-methionine + 3-hydroxy-4-methyl-anthranilyl-L-threonyl-D-valyl-[AcmD_acyl-carrier_protein] + L-valine + L-proline + glycine + ATP <=> 3-hydroxy-4-methyl-anthranilate_pentapeptide_lactone + S-adenosyl-L-homocysteine + holo-[AcmD_acyl-carrier_protein] + ADP + phosphate + H+ 6.3.1

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