Pathway Search

acetyl CoA biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
malonate_semialdehyde + CoA + NAD+ <=> acetyl-CoA + CO2 + NADH malonate-semialdehyde dehydrogenase (acetylating) methylmalonate-semialdehyde dehydrogenase (CoA-acylating)

NADP+ + H2O + malonate_semialdehyde <=> malonate + NADPH + H+ malonate-semialdehyde dehydrogenase succinate-semialdehyde dehydrogenase [NAD(P)+] succinate-semialdehyde dehydrogenase (NADP+)

CoA + acetate + ATP <=> phosphate + acetyl-CoA + ADP acetate---CoA ligase acetate---CoA ligase (ADP-forming)

acetyl-CoA + malonate <=> acetate + malonyl-CoA malonyl-S-ACP:biotin-protein carboxyltransferase malonate CoA-transferase

H2O + acetyl-CoA <=> H+ + acetate + CoA acetyl-CoA C-acyltransferase carboxymethylproline synthase homoserine O-acetyltransferase hydroxymethylglutaryl-CoA synthase 2-isopropylmalate synthase acetyl-CoA hydrolase (S)-methylmalonyl-CoA hydrolase ADP-dependent short-chain-acyl-CoA hydrolase acyl-CoA hydrolase 4-hydroxybenzoyl-CoA thioesterase phenylacetyl-CoA hydrolase fluoroacetyl-CoA thioesterase

acetyl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + enzyme_N6-(S-acetyldihydrolipoyl)lysine dihydrolipoyllysine-residue acetyltransferase

H+ + malonyl-CoA <=> CO2 + acetyl-CoA carboxymethylproline synthase chalcone synthase malonyl-S-ACP decarboxylase malonyl-CoA decarboxylase

Visualization of the pathway