|
|
GDP-L-fucose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> GDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
2.4.1.68
glycoprotein 6-alpha-L-fucosyltransferase
|
–
|
| |
KEGG:
R09319
|
|
|
|
[protein]-L-asparagine + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_diphosphate + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.99.18
dolichyl-diphosphooligosaccharide---protein glycotransferase
|
–
|
| |
KEGG:
R05976
|
|
|
|
2 UDP-galactose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn <=> 2 UDP + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
2.4.1.38
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
|
–
|
| |
KEGG:
R05989
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.143
alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05985
|
|
|
|
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn + 2 H2O <=> beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn + 2 alpha-D-mannopyranose
|
3.2.1.114
mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
|
–
|
| |
KEGG:
R05984
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.261
dolichyl-P-Man:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
|
–
|
| |
KEGG:
R06261
|
|
|
|
alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol + GDP-mannose <=> alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol + GDP
|
2.4.1.131
GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
|
–
|
| |
KEGG:
R06127
|
|
|
|
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn + H2O <=> N-acetyl-D-glucosamine + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
| |
KEGG:
R09323
|
|
|
|
GDP-L-fucose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> GDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-1-Asn
|
2.4.1.214
glycoprotein 3-alpha-L-fucosyltransferase
|
–
|
| |
KEGG:
R09318
|
|
|
|
GDP-mannose + beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> GDP + alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.132
GDP-Man:Man1GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase
|
–
|
| |
KEGG:
R05973
|
|
|
|
UDP-N-acetyl-D-glucosamine + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.101
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05983
|
|
|
|
GDP-mannose + diphosphodolichyl-N-acetyl-D-glucosaminyl-N-acetyl-D-glucosamine <=> beta-(1->4)-D-mannosylchitobiosyldiphosphodolichol + GDP + H+
|
2.4.1
2.4.1.142
chitobiosyldiphosphodolichol beta-mannosyltransferase
|
–
–
|
| |
BRENDA:
BR47411
KEGG:
R04331;
R04502;
R05972
MetaCyc:
2.4.1.142-RXN
|
|
|
|
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-[alpha-L-Fuc-(1->3)]-D-GlcNAc + H2O <=> alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-1-Asn + N-acetyl-D-glucosamine
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
| |
KEGG:
R11317
|
|
|
|
GDP-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> GDP + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.232
initiation-specific alpha-1,6-mannosyltransferase
|
–
|
| |
KEGG:
R08599
|
|
|
|
GDP-L-fucose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn <=> GDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-[alpha-L-Fuc-(1->3)]-D-GlcNAc
|
2.4.1.214
glycoprotein 3-alpha-L-fucosyltransferase
|
–
|
| |
KEGG:
R11318
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.258
dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase
|
–
|
| |
KEGG:
R06258
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.145
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
–
|
| |
KEGG:
R05987
|
|
|
|
GDP-L-fucose + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn <=> GDP + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-1-Asn
|
2.4.1
|
–
|
| |
KEGG:
R09324
|
|
|
|
N-acetyl-D-glucosaminyl-diphosphodolichol + UDP-N-acetyl-D-glucosamine <=> diphosphodolichyl-N-acetyl-D-glucosaminyl-N-acetyl-D-glucosamine + H+ + UDP
|
2.4.1.141
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase
|
–
|
| |
BRENDA:
BR47648
KEGG:
R04494;
R05970
MetaCyc:
2.4.1.141-RXN
|
|
|
|
UDP-galactose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
2.4.1
|
–
|
| |
KEGG:
R09320
|
|
|
|
UDP-D-xylose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.2.38
glycoprotein 2-beta-D-xylosyltransferase
|
–
|
| |
KEGG:
R06016
|
|
|
|
alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol + GDP-mannose <=> alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol + GDP
|
2.4.1.131
GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
|
–
|
| |
KEGG:
R06128
|
|
|
|
GDP-mannose + alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> GDP + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.257
GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
|
–
|
| |
KEGG:
R06238
|
|
|
|
alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn + 3 H2O <=> alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn + 3 D-mannose
|
3.2.1.113
mannosyl-oligosaccharide 1,2-alpha-mannosidase
|
–
|
| |
KEGG:
R12479
|
|
|
|
GDP-L-fucose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> GDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
2.4.1.68
glycoprotein 6-alpha-L-fucosyltransferase
|
–
|
| |
KEGG:
R05988
|
|
|
|
H2O + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
3.2.1.209
endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase
|
–
|
| |
KEGG:
R06722
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.260
dolichyl-P-Man:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
|
–
|
| |
KEGG:
R06260
|
|
