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TCA cycle V (2-oxoglutarate synthase)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
cis-aconitate + H2O <=> isocitrate aconitate hydratase

isocitrate + NADP+ <=> 2-oxoglutarate + CO2 + NADPH isocitrate---homoisocitrate dehydrogenase isocitrate dehydrogenase (NAD+) isocitrate dehydrogenase (NADP+)

(S)-malate <=> fumarate + H2O fumarate hydratase (S)-2-methylmalate dehydratase

succinate + CoA + ATP <=> succinyl-CoA + ADP + phosphate acetate---CoA ligase (ADP-forming) succinate---CoA ligase (GDP-forming) succinate---CoA ligase (ADP-forming)

(S)-malate + NAD+ <=> oxaloacetate + NADH + H+ D-lactate dehydrogenase malate dehydrogenase [NAD(P)+] L-2-hydroxycarboxylate dehydrogenase (NAD+) malate dehydrogenase L-2-hydroxycarboxylate dehydrogenase [NAD(P)+] malate dehydrogenase (oxaloacetate-decarboxylating) hydroxypyruvate reductase malate dehydrogenase (NADP+) 3-isopropylmalate dehydrogenase phosphoglycerate dehydrogenase diiodophenylpyruvate reductase

citrate <=> cis-aconitate + H2O 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) aconitate hydratase

acetyl-CoA + H2O + oxaloacetate <=> citrate + CoA + H+ citrate (Si)-synthase homocitrate synthase citrate synthase (unknown stereospecificity) citrate (Re)-synthase

electron-transfer_quinone + succinate <=> electron-transfer_quinol + fumarate succinate dehydrogenase

2-oxoglutarate + CoA + oxidized_ferredoxin <=> succinyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 2-oxoacid oxidoreductase (ferredoxin) 2-oxoglutarate synthase

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