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Sulfur metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
adenosine_5''-phosphosulfate + ATP <=> H+ + 3''-phosphoadenylyl-sulfate + ADP 2.7.1.25 adenylyl-sulfate kinase

H2O + L-homocysteine <=> Sulfide + 2-oxobutyrate + NH3 4.4.1.1 cystathionine gamma-lyase
4.4.1.11 methionine gamma-lyase
4.4.1.2 homocysteine desulfhydrase



sulfur + reduced_acceptor <=> Sulfide + acceptor not assigned

2 thiosulfate + decylubiquinone + 2 H+ <=> tetrathionate + decylubiquinol 1.8.5.2 thiosulfate dehydrogenase (quinone)

methanethiol + coenzyme_M <=> methyl-CoM + Sulfide + H+ 2.1.1.251 methylated-thiol---coenzyme M methyltransferase

an_alkanesulfonate + FMNH2 + O2 <=> an_aldehyde + sulfite + H2O + FMN + H+ 1.14.14.5 alkanesulfonate monooxygenase

taurine + 2-oxoglutarate + O2 <=> H+ + sulfite + aminoacetaldehyde + succinate + CO2 1.14.11.17 taurine dioxygenase

Sulfide + NADP+ + H2O <=> sulfite + NADPH + H+ 1.8.1.2 assimilatory sulfite reductase (NADPH)

sulfite + 2 ferricytochrome_c + H2O <=> sulfate + 2 ferricytochrome_c + 2 H+ 1.8.2.1 sulfite dehydrogenase (cytochrome)
1.8.3.1 sulfite oxidase


adenosine_5''-phosphosulfate + H2O <=> H+ + sulfate + AMP 3.6.1.29 bis(5'-adenosyl)-triphosphatase
3.6.2.1 adenylylsulfatase


3''-phosphoadenylyl-sulfate + H2O <=> adenosine_5''-phosphosulfate + phosphate 3.1.3.57 inositol-1,4-bisphosphate 1-phosphatase
3.1.3.7 3'(2'),5'-bisphosphate nucleotidase


H2O + Dimethylsulfide + ferricytochrome_b5 <=> DMSO + H+ + ferricytochrome_b5 1.7.2.3 trimethylamine-N-oxide reductase
1.8.2.4 dimethyl sulfide:cytochrome c2 reductase


menaquinone + H2O + Dimethylsulfide <=> menaquinol + DMSO 1.8.5.3 respiratory dimethylsulfoxide reductase

thiosulfate + 5 H2O + 8 ferricytochrome_c <=> 2 sulfate + 8 ferricytochrome_c + 10 H+ not assigned

3-methylthiopropionyl-CoA + FAD <=> 3-(methylthio)acryloyl-CoA + FADH2 1.3.8

adenosine_3,5''-bisphosphate + sulfite + thioredoxin_disulfide + H+ <=> 3''-phosphoadenylyl-sulfate + thioredoxin 1.8.4.8 phosphoadenylyl-sulfate reductase (thioredoxin)

S-sulfanylglutathione + O2 + H2O <=> glutathione + sulfite + H+ 1.13.11.18 persulfide dioxygenase

3-(methylthio)propanoate + CoA + ATP <=> 3-methylthiopropionyl-CoA + AMP + diphosphate 6.2.1.44 3-(methylthio)propionyl---CoA ligase

methanesulfonate + O2 + NADH <=> formaldehyde + sulfite + NAD+ + H2O 1.14.13.111 methanesulfonate monooxygenase (NADH)

3-(methylthio)propanoate + 5-methyltetrahydrofolate + H+ <=> dimethylsulfoniopropionate + tetrahydrofolate 2.1.1.269 dimethylsulfoniopropionate demethylase

dimethylsulfoniopropionate <=> H+ + Dimethylsulfide + Acrylate 4.4.1.3 dimethylpropiothetin dethiomethylase

sulfur + H2O + O2 <=> Sulfide + sulfite + H+ 1.13.11.55 sulfur oxygenase/reductase

Dimethylsulfide + O2 + NADH + H+ <=> methanethiol + formaldehyde + H2O + NAD+ 1.14.13.131 dissimilatory dimethyl sulfide monooxygenase

Sulfide + oxidized_ferredoxin + H2O <=> sulfite + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.8.7.1 assimilatory sulfite reductase (ferredoxin)

tetrathionate + 2 e- <=> 2 thiosulfate not assigned

methanesulfonate + O2 + FMNH2 <=> formaldehyde + sulfite + FMN + H2O + H+ 1.14.14.34 methanesulfonate monooxygenase (FMNH2)
1.14.14.5 alkanesulfonate monooxygenase


O-acetyl-L-serine + Sulfide <=> L-cysteine + acetate + H+ 2.5.1.47 cysteine synthase
2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase
2.5.1.65 O-phosphoserine sulfhydrylase
4.2.1.22 cystathionine beta-synthase
4.2.1.50 pyrazolylalanine synthase
4.4.1.9 L-3-cyanoalanine synthase






thiosulfate + dithioerythritol <=> sulfite + oxidized_dithiothreitol + Sulfide + H+ 2.8.1.5 thiosulfate---dithiol sulfurtransferase

DMSO + H2O + NAD+ <=> dimethyl_sulfone + NADH + H+ 1.8.1.17 dimethylsulfone reductase

L-homoserine + succinyl-CoA <=> O-succinyl-L-homoserine + CoA 2.3.1.46 homoserine O-succinyltransferase

3-(methylthio)acryloyl-CoA + H2O <=> methanethiol + acetaldehyde + CO2 + CoA 4.2.1.155 (methylthio)acryloyl-CoA hydratase

sulfite + O2 + H2O <=> H2O2 + sulfate 1.8.3.1 sulfite oxidase

Sulfide + 2 ferricytochrome_c <=> sulfur + 2 ferricytochrome_c + 2 H+ 1.8.2.3 sulfide-cytochrome-c reductase (flavocytochrome c)

Polysulfide + H2 <=> Sulfide + Polysulfide 1.12.98.4 sulfhydrogenase

H2O + 3''-phosphoadenylyl-sulfate <=> adenosine_3,5''-bisphosphate + H+ + sulfate 3.6.2.2 phosphoadenylylsulfatase

AMP + sulfite + FAD <=> adenosine_5'-phosphosulfate + FADH2 1.8.99.2 adenylyl-sulfate reductase

S-adenosyl-L-methionine + methanethiol <=> S-adenosyl-L-homocysteine + Dimethylsulfide + H+ 2.1.1.334 methanethiol S-methyltransferase
2.1.1.9 thiol S-methyltransferase


n Sulfide + n 1,4-benzoquinone <=> Polysulfide + n hydroquinone 1.8.5.4 bacterial sulfide:quinone reductase

methanethiol + O2 + H2O <=> formaldehyde + Sulfide + H2O2 1.8.3.4 methanethiol oxidase

sulfite + Sulfide + menaquinone + H+ <=> thiosulfate + menaquinol 1.8.5.5 thiosulfate reductase (quinone)

Sulfide + glutathione + a_quinone <=> S-sulfanylglutathione + a_quinol 1.8.5.8 eukaryotic sulfide quinone oxidoreductase

sulfite + 3 NADH + 3 H+ <=> Sulfide + 3 NAD+ + 3 H2O not assigned

thiosulfate + cyanide <=> H+ + sulfite + thiocyanate 2.8.1.1 thiosulfate sulfurtransferase
2.8.1.2 3-mercaptopyruvate sulfurtransferase


sulfite + a_quinone + H2O <=> sulfate + a_quinol 1.8.5.6 sulfite dehydrogenase (quinone)

O-succinyl-L-homoserine + Sulfide <=> H+ + L-homocysteine + succinate 2.5.1
2.5.1.48 cystathionine gamma-synthase
2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase



H+ + sulfite + AMP + GSSG <=> adenosine_5''-phosphosulfate + glutathione 1.8.4.10 adenylyl-sulfate reductase (thioredoxin)
1.8.4.9 adenylyl-sulfate reductase (glutathione)
1.8.99.2 adenylyl-sulfate reductase



trithionate + H2O + acceptor + 2 H2O <=> reduced_acceptor + 3 sulfite 1.8.99.5 dissimilatory sulfite reductase

H2O + trithionate <=> H+ + sulfate + thiosulfate 3.12.1.1 trithionate hydrolase

H+ + sulfate + ATP <=> adenosine_5''-phosphosulfate + diphosphate 2.7.7.4 sulfate adenylyltransferase

Sulfide + protein_disulfide + 2 acceptor + 3 H2O <=> sulfite + protein-dithiol + 2 reduced_acceptor + 2 H+ 1.8.99.5 dissimilatory sulfite reductase

dimethyl_sulfone + 2 FMNH2 + 2 O2 <=> Methanesulfonic_acid + formaldehyde + 2 FMN + 2 H2O 1.14.14.35 dimethylsulfone monooxygenase

sulfate + H+ + ADP <=> adenosine_5''-phosphosulfate + phosphate 2.7.7.5 sulfate adenylyltransferase (ADP)

L-serine + acetyl-CoA <=> O-acetyl-L-serine + CoA 2.3.1.30 serine O-acetyltransferase

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