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Stilbenoid, diarylheptanoid and gingerol biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone not assigned

trans-5-O-caffeoylshikimate + CoA <=> caffeoyl-CoA + shikimate 2.3.1
2.3.1.133 shikimate O-hydroxycinnamoyltransferase
2.3.1.99 quinate O-hydroxycinnamoyltransferase



feruloyl-CoA + malonyl-CoA + hexanoyl-CoA + H2O <=> 1-Dehydro-[6]-gingerdione + 3 CoA + 2 CO2 not assigned

H+ + feruloyl-CoA + malonyl-CoA <=> feruloylacetyl-CoA + CoA + CO2 2.3.1.218 phenylpropanoylacetyl-CoA synthase

S-adenosyl-L-methionine + 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone <=> [6]-gingerol + S-adenosyl-L-homocysteine + H+ 2.1.1

4-coumaroyl-CoA <=> caffeoyl-CoA 1.14.13

1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione + S-adenosyl-L-methionine <=> 1-Dehydro-[6]-gingerdione + S-adenosyl-L-homocysteine 2.1.1

malonyl-CoA + cinnamoyl-CoA + H+ <=> CoA + pinosylvin + CO2 2.3.1.146 pinosylvin synthase
2.3.1.95 trihydroxystilbene synthase


S-adenosyl-L-methionine + resveratrol <=> S-adenosyl-L-homocysteine + pterostilbene + H+ 2.1.1.240 trans-resveratrol di-O-methyltransferase

5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone <=> 1-(3,4-Dihydroxyphenyl)-5-hydroxy-3-decanone not assigned

bisdemethoxycurcumin <=> demethoxycurcumin not assigned

4-coumaroyl-CoA + malonyl-CoA + hexanoyl-CoA + H2O <=> (1E,4Z)-5-hydroxy-1-(4-hydroxyphenyl)deca-1,4-dien-3-one + 3 CoA + 2 CO2 not assigned

4-coumaroyl-CoA + (4-coumaroyl)acetyl-CoA + H2O <=> bisdemethoxycurcumin + CoA + CO2 2.3.1.219 demethoxycurcumin synthase

1-Dehydro-[6]-gingerdione <=> [6]-gingerol not assigned

resveratrol <=> piceatannol 1.14

4-coumaroyl-CoA + feruloylacetyl-CoA + H2O <=> demethoxycurcumin + CoA + CO2 2.3.1.219 demethoxycurcumin synthase

(1E,4Z)-5-hydroxy-1-(4-hydroxyphenyl)deca-1,4-dien-3-one <=> 1-(3,4-Dihydroxyphenyl)-1-decene-3,5-dione not assigned

cinnamoyl-CoA + reduced_flavodoxin + O2 <=> 4-coumaroyl-CoA + flavin + H2O 1.14.14.91 trans-cinnamate 4-monooxygenase

4-coumaroyl-CoA + shikimate <=> 4-coumaroylshikimate + CoA 2.3.1.133 shikimate O-hydroxycinnamoyltransferase
2.3.1.140 rosmarinate synthase
2.3.1.99 quinate O-hydroxycinnamoyltransferase



4-coumaroylshikimate + reduced_flavodoxin + O2 <=> trans-5-O-caffeoylshikimate + flavin + H2O 1.14.14.96 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase

4-coumaroyl-CoA + quinate <=> 5-O-p-coumaroylquinic_acid + CoA 2.3.1.133 shikimate O-hydroxycinnamoyltransferase
2.3.1.99 quinate O-hydroxycinnamoyltransferase


chlorogenic_acid + CoA <=> caffeoyl-CoA + quinate 2.3.1
2.3.1.133 shikimate O-hydroxycinnamoyltransferase
2.3.1.99 quinate O-hydroxycinnamoyltransferase



UDP-glucose + Curcumin_monoglucoside <=> H+ + Curcumin_diglucoside + UDP 2.4.1

feruloyl-CoA + (4-coumaroyl)acetyl-CoA + H2O <=> demethoxycurcumin + CoA + CO2 2.3.1.217 curcumin synthase
2.3.1.219 demethoxycurcumin synthase


(1E,4Z)-5-hydroxy-1-(4-hydroxyphenyl)deca-1,4-dien-3-one <=> 5-Hydroxy-1-(4-hydroxyphenyl)-3-decanone not assigned

UDP-glucose + curcumin <=> Curcumin_monoglucoside + UDP + H+ 2.4.1

H+ + 4-coumaroyl-CoA + malonyl-CoA <=> (4-coumaroyl)acetyl-CoA + CoA + CO2 2.3.1.218 phenylpropanoylacetyl-CoA synthase

S-adenosyl-L-methionine + caffeoyl-CoA <=> H+ + feruloyl-CoA + S-adenosyl-L-homocysteine 2.1.1.104 caffeoyl-CoA O-methyltransferase

demethoxycurcumin <=> curcumin not assigned

4-coumaroyl-CoA + malonyl-CoA + H2O + H+ <=> CoA + bisdemethoxycurcumin + CO2 2.3.1.211 bisdemethoxycurcumin synthase

5-O-p-coumaroylquinic_acid + reduced_flavodoxin + O2 <=> chlorogenic_acid + flavin + H2O 1.14.14.96 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase

H+ + 4-coumaroyl-CoA + malonyl-CoA <=> resveratrol + CoA + CO2 2.3.1.146 pinosylvin synthase
2.3.1.95 trihydroxystilbene synthase


feruloyl-CoA + feruloylacetyl-CoA + H2O <=> curcumin + CoA + CO2 2.3.1.217 curcumin synthase

Visualization of the pathway