|
|
rhodopsin + light <=> Bathorhodopsin
|
not assigned
|
–
|
| |
KEGG:
R02905
|
|
|
|
9-cis-retinal + O2 + H2O <=> 9-cis-retinoic_acid + H2O2
|
1.2.3.1
aldehyde oxidase
|
–
|
| |
BRENDA:
BS258270
KEGG:
R08384
|
|
|
|
retinoic_acid + reduced_flavodoxin + O2 <=> all-trans-18-Hydroxyretinoic_acid + flavin + H2O
|
1.14.13
1.14.14
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
| |
KEGG:
R08390
|
|
|
|
all-trans-retinal + H2O + O2 <=> retinoic_acid + H2O2 + H+
|
1.2.3.1
aldehyde oxidase
|
–
|
| |
BRENDA:
BS258268
KEGG:
R02125
MetaCyc:
RXN-13681
|
|
|
|
9-cis-retinol + NAD+ <=> 9-cis-retinal + NADH + H+
|
1.1.1
1.1.1.1
alcohol dehydrogenase
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.315
11-cis-retinol dehydrogenase
|
–
–
–
–
|
| |
BRENDA:
BS186927
KEGG:
R08382
MetaCyc:
RXN-12562
SABIO-RK:
8039
|
|
|
|
all-trans-retinyl_ester + H2O <=> 11-cis-retinol + fatty_acid + H+
|
3.1.1.64
retinoid isomerohydrolase
|
–
|
| |
BRENDA:
BS415526
KEGG:
R08388
MetaCyc:
RXN-12550
|
|
|
|
rhodopsin <=> 11-cis-retinal
|
not assigned
|
–
|
| |
KEGG:
R02904
|
|
|
|
all-trans-retinol + NAD+ <=> all-trans-retinal + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.300
NADP-retinol dehydrogenase
1.1.1.315
11-cis-retinol dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
|
–
–
–
–
–
|
| |
BRENDA:
BS186926
KEGG:
R02124
MetaCyc:
RETINOL-DEHYDROGENASE-RXN
SABIO-RK:
2114
|
|
|
|
all-trans-retinol + O2 + reduced_adrenodoxin + H+ <=> 3,4-didehydroretinol + H2O + oxidized_ferredoxin
|
1.14.19.53
all-trans-retinol 3,4-desaturase
|
–
|
| |
BRENDA:
BR52311
KEGG:
R11952
MetaCyc:
RXN-18778
|
|
|
|
1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine + 11-cis-retinol <=> 11-cis-retinyl_palmitate + 2-acylglycerophosphocholine
|
2.3.1.135
phosphatidylcholine---retinol O-acyltransferase
|
–
|
| |
KEGG:
R08389
|
|
|
|
11-cis-retinal <=> 11-cis-retinal
|
not assigned
|
–
|
| |
KEGG:
R03836
|
|
|
|
9-cis-retinol + NADP+ <=> 9-cis-retinal + NADPH
|
1.1.1
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.300
NADP-retinol dehydrogenase
1.1.1.315
11-cis-retinol dehydrogenase
|
–
–
–
–
–
–
–
|
| |
BRENDA:
BS187639
KEGG:
R08383
SABIO-RK:
10183
|
|
|
|
retinyl_palmitate + H2O <=> all-trans-retinol + palmitate + H+
|
3.1.1
3.1.1.1
carboxylesterase
3.1.1.13
sterol esterase
3.1.1.3
triacylglycerol lipase
3.1.1.64
retinoid isomerohydrolase
|
–
–
–
–
–
|
| |
BRENDA:
BS115251
KEGG:
R02368
MetaCyc:
3.1.1.64-RXN;
RETINYL-PALMITATE-ESTERASE-RXN
SABIO-RK:
2315
|
|
|
|
all-trans-retinal + NAD+ + H2O <=> retinoic_acid + NADH + H+
|
1.1.1.300
NADP-retinol dehydrogenase
1.17.3.2
xanthine oxidase
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.36
retinal dehydrogenase
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
|
–
–
–
–
–
|
| |
BRENDA:
BR36779
KEGG:
R02123
MetaCyc:
RETINAL-DEHYDROGENASE-RXN
SABIO-RK:
2113
|
|
|
|
retinoic_acid + NADPH + H+ + O2 <=> all-trans-4-Hydroxyretinoic_acid + NADP+ + H2O
|
1.14.13
1.14.14
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
| |
KEGG:
R08392
SABIO-RK:
7142
|
|
|
|
beta-carotene + O2 <=> all-trans-retinal
|
1.13.11.63
beta-carotene 15,15'-dioxygenase
|
–
|
| |
BRENDA:
BR40383
KEGG:
R00032
MetaCyc:
RXN-13374
SABIO-RK:
623
|
|
|
|
all-trans-retinol + NADP+ <=> all-trans-retinal + NADPH + H+
|
1.1.1
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.188
prostaglandin-F synthase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.300
NADP-retinol dehydrogenase
1.1.1.315
11-cis-retinol dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
|
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR48950
KEGG:
R08379
MetaCyc:
RXN-10841
SABIO-RK:
9941
|
|
|
|
palmitoyl-CoA + all-trans-retinol <=> retinyl_palmitate + CoA
|
2.3.1.76
retinol O-fatty-acyltransferase
|
–
|
| |
BRENDA:
BS321311
KEGG:
R02367
MetaCyc:
RXN-12547
SABIO-RK:
2314
|
|
|
|
phosphatidylcholine + all-trans-retinol <=> 2-acylglycerophosphocholine + all-trans-retinyl_ester
|
2.3.1.135
phosphatidylcholine---retinol O-acyltransferase
|
–
|
| |
BRENDA:
BR47558
KEGG:
R08387
|
|
|
|
H2O + 11-cis-retinyl_palmitate <=> H+ + palmitate + 11-cis-retinol
|
3.1.1.63
11-cis-retinyl-palmitate hydrolase
|
–
|
| |
BRENDA:
BR19192
KEGG:
R03049
MetaCyc:
11-CIS-RETINYL-PALMITATE-HYDROLASE-RXN
|
|
|
|
11-cis-retinol + NAD+ <=> 11-cis-retinal + NADH
|
1.1.1
1.1.1.1
alcohol dehydrogenase
1.1.1.300
NADP-retinol dehydrogenase
1.1.1.315
11-cis-retinol dehydrogenase
|
–
–
–
–
|
| |
BRENDA:
BS186928
KEGG:
R03048
SABIO-RK:
2894
|
|
|
|
Lumirhodopsin <=> Metarhodopsin
|
not assigned
|
–
|
| |
KEGG:
R06194
|
|
|
|
all-trans-retinal <=> Metarhodopsin
|
not assigned
|
–
|
| |
KEGG:
R02127
|
|
|
|
all-trans-13,14-dihydroretinol + acceptor <=> all-trans-retinol + reduced_acceptor
|
1.3.99.23
all-trans-retinol 13,14-reductase
|
–
|
| |
BRENDA:
BR48575
KEGG:
R07163
MetaCyc:
1.3.99.23-RXN
|
|
|
|
all-trans-retinal <=> 11-cis-retinal + light
|
not assigned
|
–
|
| |
KEGG:
R02128
|
|
|
|
retinoic_acid + NADPH + H+ + O2 <=> all-trans-5,6-Epoxyretinoic_acid + NADP+ + H2O
|
1.14.13
1.14.14.1
unspecific monooxygenase
|
–
–
|
| |
KEGG:
R08391
|
|
|
|
9-cis-retinal + NAD+ + H2O <=> 9-cis-retinoic_acid + NADH + H+
|
1.2.1
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.36
retinal dehydrogenase
|
–
–
–
|
| |
BRENDA:
BS370839
KEGG:
R08385
MetaCyc:
RXN-21047
|
|
|
|
palmitoyl-CoA + 11-cis-retinol <=> CoA + 11-cis-retinyl_palmitate
|
2.3.1.75
long-chain-alcohol O-fatty-acyltransferase
2.3.1.76
retinol O-fatty-acyltransferase
|
–
–
|
| |
BRENDA:
BS377461
KEGG:
R08381
SABIO-RK:
13990
|
|
|
|
UDP-glucuronate + retinoic_acid <=> UDP + all-trans-retinoic_acid_beta-D-glucuronoside
|
2.4.1.17
glucuronosyltransferase
|
–
|
| |
BRENDA:
BS436001
KEGG:
R02902
SABIO-RK:
2762
|
|
|
|
11-cis-retinol + NADP+ <=> 11-cis-retinal + NADPH + H+
|
1.1.1
1.1.1.300
NADP-retinol dehydrogenase
1.1.1.315
11-cis-retinol dehydrogenase
|
–
–
–
|
| |
BRENDA:
BS371534
KEGG:
R08380
MetaCyc:
RXN-13363
|
|
|
|
Bathorhodopsin <=> Lumirhodopsin
|
not assigned
|
–
|
| |
KEGG:
R05041
|
|
|
|
all-trans-retinol + acyl-CoA <=> all-trans-retinyl_ester + CoA
|
2.3.1.76
retinol O-fatty-acyltransferase
|
–
|
| |
BRENDA:
BR44078
KEGG:
R02366
MetaCyc:
RETINOL-O-FATTY-ACYLTRANSFERASE-RXN
|
|
