|
|
(1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate <=> (1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate + H2O + H+
|
not assigned
|
–
|
|
KEGG:
R11568
MetaCyc:
RXN-17683
|
|
|
|
(1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 <=> 5,10-dihydrophenazine_1-carboxylate + H2O2
|
1.10.3.16
dihydrophenazinedicarboxylate synthase
|
–
|
|
BRENDA:
BR51796
KEGG:
R11492
|
|
|
|
(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + O2 <=> (5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate + H2O2
|
1.10.3.16
dihydrophenazinedicarboxylate synthase
|
–
|
|
BRENDA:
BR51794
KEGG:
R11490
MetaCyc:
RXN-17685
|
|
|
|
2-aminobenzoyl-CoA + L-Cysteinyl-protein <=> S-Anthraniloyl-L-cysteinyl-protein + CoA
|
2.3.1.262
anthraniloyl-CoA anthraniloyltransferase
|
–
|
|
KEGG:
R11586
|
|
|
|
anthranilate + CoA + ATP <=> 2-aminobenzoyl-CoA + AMP + diphosphate
|
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.25
benzoate---CoA ligase
6.2.1.32
anthranilate---CoA ligase
|
–
–
–
|
|
BRENDA:
BR48384
KEGG:
R00982
MetaCyc:
AMINOBENZCOALIG-RXN
|
|
|
|
(5aS)-5,5a-dihydrophenazine-1,6-dicarboxylate <=> 5,10-Dihydrophenazine-1,6-dicarboxylate
|
not assigned
|
–
|
|
KEGG:
R11574
MetaCyc:
RXN-12020
|
|
|
|
2-heptyl-4(1H)-quinolone + NADH + O2 + H+ <=> 2-heptyl-3-hydroxy-4(1H)-quinolone + NAD+ + H2O
|
1.14.13.182
2-heptyl-3-hydroxy-4(1H)-quinolone synthase
|
–
|
|
BRENDA:
BR50587
KEGG:
R10467
MetaCyc:
RXN-11849
|
|
|
|
dimethylallyl_diphosphate + 5,10-dihydrophenazine_1-carboxylate <=> diphosphate + 5,10-dihydro-9-dimethylallylphenazine_1-carboxylate
|
2.5.1.121
5,10-dihydrophenazine-1-carboxylate 9-dimethylallyltransferase
|
–
|
|
BRENDA:
BR50879
KEGG:
R10966
MetaCyc:
RXN-15417
|
|
|
|
1-(2-aminophenyl)decane-1,3-dione <=> 2-heptyl-4(1H)-quinolone + H2O
|
2.3.1.230
2-heptyl-4(1H)-quinolone synthase
|
–
|
|
BRENDA:
BR51959
KEGG:
R11590
MetaCyc:
RXN-17705
|
|
|
|
(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate <=> (1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate
|
not assigned
|
–
|
|
KEGG:
R11571
MetaCyc:
RXN-17692
|
|
|
|
(5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic_acid <=> (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate
|
5.3.3.17
trans-2,3-dihydro-3-hydroxyanthranilate isomerase
|
–
|
|
BRENDA:
BR49351
KEGG:
R09707
MetaCyc:
RXN-9031
|
|
|
|
chorismate + L-glutamine <=> (2S)-2-amino-4-deoxy-chorismate + L-glutamate
|
2.6.1.85
aminodeoxychorismate synthase
2.6.1.86
2-amino-4-deoxychorismate synthase
|
–
–
|
|
BRENDA:
BR48884
KEGG:
R08956
MetaCyc:
RXN-9028
SABIO-RK:
15416
|
|
|
|
(2S)-2-amino-4-deoxy-chorismate + H2O <=> (5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic_acid + pyruvate
|
3.3.2.15
trans-2,3-dihydro-3-hydroxyanthranilic acid synthase
3.3.2.B1
|
–
–
|
|
BRENDA:
BR49262
KEGG:
R11463
MetaCyc:
RXN-9030
|
|
|
|
(1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + O2 <=> (10aS)-10,10a-dihydrophenazine-1-carboxylate + H2O2
|
1.10.3.16
dihydrophenazinedicarboxylate synthase
|
–
|
|
BRENDA:
BR51795
KEGG:
R11491
MetaCyc:
RXN-17690
|
|
|
|
2-aminobenzoylacetyl-CoA + H2O <=> 2-aminobenzoylacetate + CoA + H+
|
3.1.2.32
2-aminobenzoylacetyl-CoA thioesterase
|
–
|
|
BRENDA:
BR51771
KEGG:
R11542
MetaCyc:
RXN-17703
|
|
|
|
(1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate <=> (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + H2O
|
not assigned
|
–
|
|
KEGG:
R11569
MetaCyc:
RXN-17684
|
|
|
|
S-adenosyl-L-methionine + phenazine-1-carboxylic_acid <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine
|
2.1.1.327
phenazine-1-carboxylate N-methyltransferase
|
–
|
|
BRENDA:
BR51748
KEGG:
R11533
MetaCyc:
RXN-11897
|
|
|
|
chorismate + L-glutamine <=> H+ + anthranilate + L-glutamate + pyruvate
|
4.1.3.27
anthranilate synthase
|
–
|
|
BRENDA:
BR3373
KEGG:
R00986
MetaCyc:
ANTHRANSYN-RXN
SABIO-RK:
1280
|
|
|
|
5,10-Dihydrophenazine + O2 <=> phenazine + H2O2
|
not assigned
|
–
|
|
KEGG:
R11573
MetaCyc:
RXN-17696
|
|
|
|
5,10-dihydrophenazine_1-carboxylate + O2 <=> phenazine-1-carboxylic_acid + H2O2
|
not assigned
|
–
|
|
KEGG:
R11577
MetaCyc:
RXN-17694
|
|
|
|
5-methylphenazine-1-carboxylate + NADH + O2 + H+ <=> pyocyanine + NAD+ + CO2 + H2O
|
1.14.13.218
5-methylphenazine-1-carboxylate 1-monooxygenase
|
–
|
|
BRENDA:
BR51667
KEGG:
R11346
MetaCyc:
RXN-11898
|
|
|
|
octanoyl-CoA + L-Cysteinyl-protein <=> S-Octanoyl-L-cysteinyl-protein + CoA
|
2.3.1.230
2-heptyl-4(1H)-quinolone synthase
|
–
|
|
KEGG:
R10590
|
|
|
|
(1R)-1,4,5,10-tetrahydrophenazine-1-carboxylate + O2 + H+ <=> 5,10-Dihydrophenazine + H2O2 + CO2
|
not assigned
|
–
|
|
KEGG:
R11572
MetaCyc:
RXN-17695
|
|
|
|
S-Anthraniloyl-L-cysteinyl-protein + malonyl-CoA <=> 2-aminobenzoylacetyl-CoA + CO2 + S-Anthraniloyl-L-cysteinyl-protein
|
2.3.1.262
anthraniloyl-CoA anthraniloyltransferase
|
–
|
|
KEGG:
R11587
|
|
|
|
(10aS)-10,10a-dihydrophenazine-1-carboxylate <=> 5,10-dihydrophenazine_1-carboxylate
|
not assigned
|
–
|
|
KEGG:
R11576
MetaCyc:
RXN-17691
|
|
|
|
phenazine-1-carboxylic_acid + NADH + O2 + H+ <=> 1-hydroxyphenazine + NAD+ + CO2 + H2O
|
1.14.13.218
5-methylphenazine-1-carboxylate 1-monooxygenase
|
–
|
|
KEGG:
R11578
MetaCyc:
RXN-17175
|
|
|
|
5,10-Dihydrophenazine-1,6-dicarboxylate + O2 <=> Phenazine-1,6-dicarboxylate + H2O2
|
not assigned
|
–
|
|
KEGG:
R11575
MetaCyc:
RXN-17687
|
|
|
|
(1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1,6-dicarboxylate + H2O2
|
1.10.3.16
dihydrophenazinedicarboxylate synthase
|
–
|
|
BRENDA:
BR51793;
BS436586
KEGG:
R11489
MetaCyc:
RXN-12021
|
|
|
|
(1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 + H+ <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + H2O2 + CO2
|
not assigned
|
–
|
|
KEGG:
R11570
MetaCyc:
RXN-17689
|
|
|
|
S-Octanoyl-L-cysteinyl-protein + 2-aminobenzoylacetate <=> 1-(2-aminophenyl)decane-1,3-dione + CO2 + L-Cysteinyl-protein
|
2.3.1.230
2-heptyl-4(1H)-quinolone synthase
|
–
|
|
KEGG:
R11589
|
|