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Microbial metabolism in diverse environments

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
5-hydroxyisourate + H2O <=> 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate 3.5.2.17 hydroxyisourate hydrolase
–
salicylate + NADPH + H+ + O2 <=> 2,5-Dihydroxybenzoate + NADP+ + H2O 1.14.13.172 salicylate 5-hydroxylase
–
H+ + vetrazine + H2O <=> N-Cyclopropylammeline + NH3 3.5.4
–
NO + H2O + ferricytochrome_c <=> nitrite + ferricytochrome_c + 2 H+ 1.7.2.1 nitrite reductase (NO-forming)
1.7.2.6 hydroxylamine dehydrogenase
–
–
3-(2,3-dihydroxyphenyl)propanoate + O2 <=> H+ + (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate 1.13.11.16 3-carboxyethylcatechol 2,3-dioxygenase
–
(S)-allantoin + H2O <=> H+ + Allantoate 3.5.2.5 allantoinase
–
7-Oxoheptanoic_acid <=> 7-Mercaptoheptanoic_acid not assigned
 –
(S)-Mandelate + FMN <=> benzoylformate + FMNH2 1.1.99.31 (S)-mandelate dehydrogenase
–
H2O + 4-Fumarylacetoacetate <=> H+ + fumarate + acetoacetate 3.7.1.2 fumarylacetoacetase
–
3-hydroxyphenylacetate + NADPH + O2 + H+ <=> homogentisate + NADP+ + H2O 1.14.13.63 3-hydroxyphenylacetate 6-hydroxylase
–
D-erythrose_4-phosphate + D-xylulose_5-phosphate <=> beta-D-fructose_6-phosphate + D-glyceraldehyde_3-phosphate 2.2.1.1 transketolase
2.2.1.3 formaldehyde transketolase
–
–
1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ <=> 3-methylcatechol + CO2 + NADH + H+ 1.3.1
–
H+ + o-Cresol + NADH + O2 <=> 3-methylcatechol + NAD+ + H2O 1.14.13.236 toluene 4-monooxygenase
1.14.13.243 toluene 2-monooxygenase
1.14.13.44 2-hydroxybiphenyl 3-monooxygenase
1.14.13.7 phenol 2-monooxygenase (NADPH)
–
–
–
–
4-hydroxy-3-methylbenzoate <=> 4-Hydroxyisophthalate not assigned
 –
oxaloacetate + ITP <=> CO2 + phosphoenolpyruvate + IDP 4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
4.1.1.49 phosphoenolpyruvate carboxykinase (ATP)
–
–
(3S)-3-carboxy-3-hydroxypropanoyl-CoA <=> glyoxylate + acetyl-CoA 4.1.3.24 malyl-CoA lyase
–
3-chloro-2-methyl-dienelactone + H2O <=> 3-chloro-2-methylmaleylacetate + H+ 3.1.1.45 carboxymethylenebutenolidase
–
ATP + L-rhamnulose <=> ADP + L-rhamnulose_1-phosphate 2.7.1.5 rhamnulokinase
–
cholesterol + NAD+ <=> cholest-4-en-3-one + NADH + H+ 1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
5.3.3.1 steroid Delta-isomerase
–
–
2,4-Dichlorophenoxyacetic_acid + H+ + 2 e- <=> 4-Chlorophenoxyacetate + Cl- 1.97.1
–
S-hydroxymethylglutathione + NAD+ <=> S-formylglutathione + NADH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase
1.2.1.46 formaldehyde dehydrogenase
–
–
–
–
2-hydro-1,2-dihydroxybenzoate + NAD+ <=> catechol + CO2 + NADH 1.3.1.25 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
–
D-ribose_5-phosphate <=> D-ribulose_5-phosphate 5.3.1.6 ribose-5-phosphate isomerase
–
Sulfide + NADP+ + H2O <=> sulfite + NADPH + H+ 1.8.1.2 assimilatory sulfite reductase (NADPH)
–
thiobenzamide + O2 + NADPH + H+ <=> Thiobenzamide_S-oxide + NADP+ + H2O 1.14.13
–
9-fluorenone + NADH + H+ + O2 <=> 1,1a-dihydroxy-1-hydrofluoren-9-one + NAD+ 1.14.12
1.14.12.22 carbazole 1,9a-dioxygenase
–
–
NAD+ + (1S,2R)-3-Methylcyclohexa-3,5-diene-1,2-diol <=> H+ + NADH + 3-methylcatechol 1.3.1.19 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane <=> H+ + 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + Cl- 4.5.1.1 DDT-dehydrochlorinase
–
sedoheptulose_1,7-diphosphate <=> dihydroxyacetone_phosphate + D-erythrose_4-phosphate 4.1.2.13 fructose-bisphosphate aldolase
–
xylene + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> 3-methylbenzyl_alcohol + oxidized_ferredoxin + H2O 1.14.15.26 toluene methyl-monooxygenase
–
Sulfide + oxidized_ferredoxin + H2O <=> sulfite + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.8.7.1 assimilatory sulfite reductase (ferredoxin)
–
beta-D-glucose_6-phosphate <=> beta-D-fructose_6-phosphate 5.3.1.9 glucose-6-phosphate isomerase
–
NH3 + NADP+ + H2O <=> nitrite + NADPH + H+ 1.7.1.4 nitrite reductase [NAD(P)H]
1.7.7.1 ferredoxin---nitrite reductase
1.8.1.2 assimilatory sulfite reductase (NADPH)
–
–
–
5-Aminopentanamide + H2O <=> 5-Aminopentanoate + NH3 3.5.1.30 5-aminopentanamidase
–
L-threo-3-methylaspartate <=> NH3 + mesaconate 4.3.1.2 methylaspartate ammonia-lyase
–
succinate_semialdehyde + NADP+ + CoA <=> succinyl-CoA + NADPH + H+ 1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)
1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
–
–
tetrachlorohydroquinone + NAD+ + H+ <=> tetrafluoro-1,4-benzoquinone + NADH 1.1.1.404 tetrachlorobenzoquinone reductase
–
scyllo-inosose <=> H2O + 3D-3,5/4-trihydroxycyclohexa-1,2-dione 4.2.1.44 myo-inosose-2 dehydratase
–
4-methylaminobutanoate + O2 + H2O <=> 4-aminobutanoate + formaldehyde + H2O2 1.5.3.19 4-methylaminobutanoate oxidase (formaldehyde-forming)
–
H+ + sulfate + ATP <=> adenosine_5''-phosphosulfate + diphosphate 2.7.7.4 sulfate adenylyltransferase
–
Benzo[a]pyrene-trans-11,12-dihydrodiol <=> 11,12-Dihydroxybenzo[a]pyrene 1.3
–
ATP + NH3 + CO2 + H2O <=> ADP + phosphate + Carbamoyl_phosphate 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
–
–
4-Aminobenzoic_acid + O2 + NADH + H+ <=> 4-Aminophenol + CO2 + H2O + NAD+ 1.14.13.27 4-aminobenzoate 1-monooxygenase
–
2,4-Diamino-6-hydroxylaminotoluene <=> 2,4,6-Triaminotoluene 1.8.99.5 dissimilatory sulfite reductase
–
cyclohexa-1,5-diene-1-carbonyl-CoA <=> cyclohexa-2,5-diene-1-carbonyl-CoA not assigned
 –
2-methyl-p-cresol + 4 oxidized_azurin + H2O <=> 3-Methyl-4-hydroxybenzaldehyde + 4 azurin + 4 H+ 1.17.9.1 4-methylphenol dehydrogenase (hydroxylating)
–
Acetylene + H2O <=> acetaldehyde 4.2.1.112 acetylene hydratase
–
H+ + N-Cyclopropylammeline + H2O <=> N-cyclopropylammelide + NH3 3.5.4
–
O2 + 2,3-Dihydroxybenzoate <=> H+ + 3-carboxy-2-hydroxymuconate_semialdehyde 1.13.11.14 2,3-dihydroxybenzoate 3,4-dioxygenase
–
pyridoxal + NAD+ <=> 4-Pyridoxolactone + NADH + H+ 1.1.1.107 pyridoxal 4-dehydrogenase
–
4-methyl-5-nitrocatechol + O2 + NADPH <=> H+ + 2-hydroxy-5-methylquinone + NADP+ + nitrite + H2O 1.14.13.210 4-methyl-5-nitrocatechol 5-monooxygenase
–
6-carboxyhex-2-enoyl-CoA + H2O <=> 3-hydroxypimeloyl-CoA 4.2.1
–
1,1a-dihydroxy-1-hydrofluoren-9-one + H2O <=> 2,3-Dihydroxy-2''-carboxybiphenyl + 2 H+ 1.3
–
3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA <=> 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate 6.2.1.41 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate---CoA ligase
–
H2O + dihydrocoumarin <=> H+ + melilotate 3.1.1.25 1,4-lactonase
3.1.1.35 dihydrocoumarin hydrolase
–
–
D-fructose_1,6-bisphosphate <=> dihydroxyacetone_phosphate + D-glyceraldehyde_3-phosphate 4.1.2.13 fructose-bisphosphate aldolase
4.1.2.40 tagatose-bisphosphate aldolase
–
–
2,4,5-trichloro-2,5-cyclohexadiene-1-ol + H2O <=> 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + Hydrochloric_acid 3.8.1.5 haloalkane dehalogenase
–
D-fructose_1,6-bisphosphate + H2O <=> beta-D-fructose_6-phosphate + phosphate 3.1.3.11 fructose-bisphosphatase
3.1.3.29 N-acylneuraminate-9-phosphatase
3.1.3.37 sedoheptulose-bisphosphatase
3.1.3.7 3'(2'),5'-bisphosphate nucleotidase
–
–
–
–
trans-cinnamate <=> 3-hydroxycinnamic_acid not assigned
 –
(S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate <=> 4-Hydroxy-D-mandelate 5.1.2.2 mandelate racemase
–
L-aspartate + ATP <=> L-4-aspartyl_phosphate + ADP 2.7.2.4 aspartate kinase
–
L-ribulose_5-phosphate <=> D-xylulose_5-phosphate 5.1.3.4 L-ribulose-5-phosphate 4-epimerase
–
anthranilate + O2 + NADPH + H+ <=> catechol + CO2 + NH3 + NADP+ 1.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
–
benzo[a]pyrene + NADH + H+ + O2 <=> Benzo[a]pyrene-cis-11,12-dihydrodiol + NAD+ 1.14.12
–
phenanthrene + O2 + NADH + H+ <=> Phenanthrene-1,2-oxide + H2O + NAD+ 1.14.13
–
5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O <=> H+ + 5-formyl-5,6,7,8-tetrahydromethanopterin 3.5.4.27 methenyltetrahydromethanopterin cyclohydrolase
–
N-hydroxyaniline + NADP+ <=> nitrosobenzene + NADPH + H+ 1.7.1.16 nitrobenzene nitroreductase
–
Tribromobisphenol_A <=> Dibromobisphenol_A + Hydrobromic_acid 1.97.1
–
D-glyceraldehyde + H2O + NADP+ <=> D-glycerate + NADPH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.26 2,5-dioxovalerate dehydrogenase
1.2.1.4 aldehyde dehydrogenase (NADP+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.8 betaine-aldehyde dehydrogenase
1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
–
–
–
–
–
–
S-adenosyl-L-methionine + uroporphyrinogen_III <=> S-adenosyl-L-homocysteine + precorrin-2 + H+ 2.1.1.107 uroporphyrinogen-III C-methyltransferase
–
5-methoxygallic_acid + O2 <=> H+ + 4-carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate 1.13.11
1.13.11.8 protocatechuate 4,5-dioxygenase
–
–
4-hydroxy-4-methyl-2-oxoglutarate <=> pyruvate 4.1.3.17 4-hydroxy-4-methyl-2-oxoglutarate aldolase
–
2-hydroxy-2H-chromene-2-carboxylate <=> (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate 2.5.1.18 glutathione transferase
5.99.1.4 2-hydroxychromene-2-carboxylate isomerase
–
–
bisphenol_A <=> 5-Hydroxybisphenol_A not assigned
 –
2,4,5-Trichlorophenol + O2 + FADH2 <=> 2,5-dichlorohydroquinone + Cl- + H2O + FAD + H+ 1.14.14
–
protoanemonin + H2O <=> cis-acetylacrylate 3.1.1.45 carboxymethylenebutenolidase
–
beta-2,3,4,5,6-Pentachlorocyclohexanol + H2O <=> beta-2,3,5,6-Tetrachloro-1,4-cyclohexanediol + Hydrochloric_acid 3.8.1.5 haloalkane dehalogenase
–
beta-hexachlorocyclohexane <=> delta-3,4,5,6-Tetrachlorocyclohexene + 2 Cl- not assigned
 –
4-Carboxymethyl-3-methylbut-2-en-1,4-olide <=> 4-methyl-3-oxoadipate_enol-lactone 5.3.3
5.3.3.4 muconolactone Delta-isomerase
5.4.99.14 4-carboxymethyl-4-methylbutenolide mutase
5.5.1
–
–
–
–
cyanuric_acid + H2O <=> carboxybiuret + H+ 3.5.2.15 cyanuric acid amidohydrolase
–
2,2,2-trichloroethanol <=> chloral 1.1
–
(2E,4Z)-2-hydroxyhexa-2,4-dienoate + H2O <=> 4-hydroxy-2-oxohexanoate 4.2.1.132 2-hydroxyhexa-2,4-dienoate hydratase
–
cis,cis-2,4-Dihydroxy-5-methyl-6-oxo-2,4-hexadienoate + H2O <=> L-2-methyl-3-oxopropionate + pyruvate 3.7.1
–
H2O + cyclohexyl_sulfamate <=> sulfate + Cyclohexylamine 3.10.1.2 cyclamate sulfohydrolase
–
bithionol + phosphate + ADP <=> 3-hydroxypropionate + CoA + ATP 6.2.1
–
H+ + 1,4-benzoquinone + NADPH <=> hydroquinone + NADP+ 1.1.1.328 nicotine blue oxidoreductase
1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.6.5.10 NADPH dehydrogenase (quinone)
1.6.5.2 NAD(P)H dehydrogenase (quinone)
1.6.5.5 NADPH:quinone reductase
1.6.5.6 p-benzoquinone reductase (NADPH)
1.7.1.6 azobenzene reductase
1.8.1.9 thioredoxin-disulfide reductase
–
–
–
–
–
–
–
–
acetyl-CoA + L-lactate <=> acetate + lactoyl-CoA 2.8.3.1 propionate CoA-transferase
–
Caffeine + NADPH + O2 + H+ <=> Theobromine + NADP+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
1.14.13.178 methylxanthine N1-demethylase
–
–
NTP + pyruvate <=> NDP + phosphoenolpyruvate 2.7.1.40 pyruvate kinase
–
2-Fluorobenzoate + NADH + H+ + O2 <=> 2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ 1.14.12.10 benzoate 1,2-dioxygenase
–
D-glucose + NAD+ <=> D-glucono-1,5-lactone + NADH + H+ 1.1.1.118 glucose 1-dehydrogenase (NAD+)
1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.121 aldose 1-dehydrogenase (NAD+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
–
–
–
–
–
(2R,3S)-dimethylmalate <=> dimethylmaleate + H2O 4.2.1.85 dimethylmaleate hydratase
–
D-lactate + H+ <=> methylglyoxal + H2O 3.5.1.124 protein deglycase
4.2.1.130 D-lactate dehydratase
–
–
5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + H2O + NAD+ <=> 3-hydroxy-2-methylpyridine-4,5-dicarboxylate + NADH + H+ 1.2.1.100 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase
–
NH3 + H2O + oxidized_ferredoxin <=> nitrite + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.7.7.1 ferredoxin---nitrite reductase
1.8.7.1 assimilatory sulfite reductase (ferredoxin)
–
–
D-chiro-Inositol + NAD+ <=> 2D-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+ 1.1.1.18 inositol 2-dehydrogenase
1.1.1.369 D-chiro-inositol 1-dehydrogenase
–
–
(2S)-2-phospholactate + GTP + H+ <=> L-lactyl-2-diphospho-5''-guanosine + diphosphate 2.7.7.68 2-phospho-L-lactate guanylyltransferase
–
H+ + 2-amino-6-(N-ethylamino)-4-hydroxy-1,3,5-triazine + H2O <=> 6-(ethylamino)-1,3,5-triazine-2,4-diol + NH3 3.5.4
3.8.1.8 atrazine chlorohydrolase
–
–
4,5-9,10-diseco-3-hydroxy-5,9,17-tri-oxoandrosta-1(10),2-diene-4-oic_acid + H2O <=> 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+ 3.7.1.17 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
–
sulfite + a_quinone + H2O <=> sulfate + a_quinol 1.8.5.6 sulfite dehydrogenase (quinone)
–
sulfate + H+ + ADP <=> adenosine_5''-phosphosulfate + phosphate 2.7.7.5 sulfate adenylyltransferase (ADP)
–
2-Hydroxy-3-carboxybenzalpyruvate + H2O <=> 3-Formylsalicylic_acid + pyruvate 4.2.1
–
Toluene + O2 + NADH + H+ <=> p-Cresol + H2O + NAD+ 1.14.13.236 toluene 4-monooxygenase
–
2,6-Diamino-4-nitrotoluene <=> 2,4,6-Triaminotoluene not assigned
 –
Furfuryl_alcohol + NAD+ <=> furfural + NADH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.265 3-methylbutanal reductase
1.1.1.307 D-xylose reductase
1.1.1.90 aryl-alcohol dehydrogenase
–
–
–
–
–
–
Caffeine + O2 + NADPH + H+ <=> theophylline + formaldehyde + NADP+ + H2O 1.13.12
1.14.13.128 7-methylxanthine demethylase
–
–
thiosulfate + 5 H2O + 8 ferricytochrome_c <=> 2 sulfate + 8 ferricytochrome_c + 10 H+ not assigned
 –
1,1,1-trichloroethane + NADH + H+ + O2 <=> 2,2,2-trichloroethanol + NAD+ + H2O 1.14.13.25 methane monooxygenase (soluble)
–
biphenyl + O2 + NADH + H+ <=> cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+ 1.14.12.18 biphenyl 2,3-dioxygenase
1.14.12.22 carbazole 1,9a-dioxygenase
–
–
2-Hydroxycyclohexan-1-one + NADPH + O2 <=> 1-Oxa-2-oxo-3-hydroxycycloheptane + NADP+ + H2O 1.14.13.22 cyclohexanone monooxygenase
–
(S)-malate + NADP+ <=> H+ + NADPH + oxaloacetate 1.1.1.299 malate dehydrogenase [NAD(P)+]
1.1.1.37 malate dehydrogenase
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.82 malate dehydrogenase (NADP+)
–
–
–
–
–
–
cis-1,2-dihydrobenzene-3-chloro-(R,R)-1,2-diol + NAD+ <=> 3-chlorocatechol + NADH + H+ 1.3.1.119 chlorobenzene dihydrodiol dehydrogenase
1.3.1.19 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
–
–
H+ + gallic_acid <=> CO2 + pyrogallol 4.1.1.59 gallate decarboxylase
4.1.1.61 4-hydroxybenzoate decarboxylase
–
–
6-amino-hexanoate_cyclic_dimer + H2O <=> N-(6-aminohexanoyl)-6-aminohexanoate 3.5.1.117 6-aminohexanoate-oligomer endohydrolase
3.5.2.12 6-aminohexanoate-cyclic-dimer hydrolase
–
–
trichloroacetate <=> CO2 not assigned
 –
N2 + H2O + 2 ferricytochrome_c <=> N2O + 2 ferricytochrome_c + 2 H+ 1.7.2.4 nitrous-oxide reductase
–
4-nitrophenol + NADH + O2 + H+ <=> 4-nitrocatechol + NAD+ + H2O 1.14.13.29 4-nitrophenol 2-monooxygenase
–
Caffeine + NADH + O2 + H+ <=> paraxanthine + NAD+ + formaldehyde + H2O 1.14.13.128 7-methylxanthine demethylase
1.14.13.179 methylxanthine N3-demethylase
–
–
2-hydroxy-2,4-hexadienedioate <=> 4-oxalocrotonate 5.3.2.6 2-hydroxymuconate tautomerase
5.3.2.M1
–
–
CoA + acetate + ATP <=> acetyl-CoA + diphosphate + AMP 6.2.1.1 acetate---CoA ligase
6.2.1.17 propionate---CoA ligase
6.2.1.36 3-hydroxypropionyl-CoA synthase
–
–
–
(Z)-pent-1-ene-1,2,5-tricarboxylate + H2O <=> (-)-threo-iso(homo)2citrate 4.2.1.114 methanogen homoaconitase
–
D-glucose <=> D-glucose 5.1.3.21 maltose epimerase
5.1.3.3 aldose 1-epimerase
–
–
L-aspartate_4-semialdehyde + NAD+ + H2O <=> L-aspartate + NADH + H+ 1.2.1
1.2.1.M5
–
–
1,4-dichlorobenzene <=> chlorobenzene not assigned
 –
H+ + Phosphonopyruvate <=> phosphonoacetaldehyde + CO2 4.1.1.82 phosphonopyruvate decarboxylase
–
2-Methyleneglutarate <=> (R)-3-methylitaconate 5.4.99.4 2-methyleneglutarate mutase
–
3-Fluorobenzoate + NADH + H+ + O2 <=> 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ 1.14.12.10 benzoate 1,2-dioxygenase
–
6-phospho-D-glucosaminate <=> 2-keto-3-deoxy_phosphogluconate + NH3 4.3.1.29 D-glucosaminate-6-phosphate ammonia-lyase
–
5-Aminopentanoate + 2-oxoglutarate <=> L-glutamate + 5-Oxopentanoate 2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2 alanine transaminase
2.6.1.48 5-aminovalerate transaminase
–
–
–
4-Aminocatechol + H2O <=> Hydroxyquinol + NH3 not assigned
 –
3,4-Dihydroxy-3,4-dihydro-9-fluorenone <=> 4-Hydroxy-9-fluorenone + H2O not assigned
 –
H2O + Phosphonoacetate <=> H+ + phosphate + acetate 3.11.1.2 phosphonoacetate hydrolase
–
4-chloroaniline + O2 + 2 H+ <=> 4-Chlorocatechol + NH3 1.14
–
Benzo[a]pyrene-cis-7,8-dihydrodiol + O2 <=> cis-4-(7-Hydroxtpyren-8-yl)-2-oxobut-3-enoate not assigned
 –
2,5-dichloromaleylacetate + NADH <=> 2-chloro-3-oxohexanedioic_acid + NAD+ + Cl- 1.3.1.32 maleylacetate reductase
–
cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene <=> 4-methylsalicylate not assigned
 –
O2 + cholesterol <=> cholest-4-en-3-one + H2O2 1.1.3.6 cholesterol oxidase
–
guaiacol + reduced_flavodoxin + O2 <=> catechol + flavin + formaldehyde + H2O 1.14.14
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H+ + salicylate + O2 + NADH <=> catechol + CO2 + H2O + NAD+ 1.14.13.1 salicylate 1-monooxygenase
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4-amino-2-nitrotoluene + 3 NADH + 3 H+ <=> 2,4-Diaminotoluene + 3 NAD+ + 2 H2O 1.7.1
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2,3-Dihydroxy-p-cumate + O2 <=> 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate + H+ 1.13.11
1.13.11.M5
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4-hydroxylamino-2,6-dinitrotoluene + NADPH + H+ <=> 4-amino-2,6-dinitrotoluene + NADP+ + H2O 1.7.1
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methylamine + L-glutamate <=> N-Methyl-L-glutamate + NH3 2.1.1.21 methylamine---glutamate N-methyltransferase
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D-glycerate + NAD+ <=> H+ + Hydroxypyruvate + NADH 1.1.1.237 hydroxyphenylpyruvate reductase
1.1.1.26 glyoxylate reductase
1.1.1.27 L-lactate dehydrogenase
1.1.1.28 D-lactate dehydrogenase
1.1.1.29 glycerate dehydrogenase
1.1.1.60 2-hydroxy-3-oxopropionate reductase
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.92 oxaloglycolate reductase (decarboxylating)
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3-isochromanone <=> catechol not assigned
 –
3-hydroxy-2-naphthoate + O2 <=> 3-[6-(Carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate 1.13.11
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nicotinate + H2O + Ferrocytochrome <=> 6-Hydroxynicotinate + Ferrocytochrome + H+ 1.17.2.1 nicotinate dehydrogenase (cytochrome)
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2-Hydroxy-2-hydropyrone-4,6-dicarboxylate + NAD+ <=> 2-Pyrone-4,6-dicarboxylate + NADH + H+ 1.1.1.312 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
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Dibromobisphenol_A <=> Monobromobisphenol_A + Hydrobromic_acid 1.97.1
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9-fluorenone + O2 + 2 NADH <=> 3,4-Dihydroxy-3,4-dihydro-9-fluorenone + 2 NAD+ 1.14.12
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2-Carboxy-2-hydroxy-8-carboxychromene <=> 2-Hydroxy-3-carboxybenzalpyruvate 5.3.99
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4-hydroxybutyrate + ATP + CoA <=> 4-hydroxybutanoyl-CoA + ADP + phosphate 6.2.1.56 4-hydroxybutyrate---CoA ligase (ADP-forming)
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3-Methyl-4-hydroxybenzaldehyde + NADP+ + H2O <=> 4-hydroxy-3-methylbenzoate + NADPH + H+ 1.2.1.96 4-hydroxybenzaldehyde dehydrogenase (NADP+)
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3,4-Dihydroxyfluorene + O2 <=> 2-Hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene)-but-2-enoic_acid 1.13.11
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1,1-Dichloro-2-(dihydroxy-4''-chlorophenyl)-2-(4''-chlorophenyl)ethylene + O2 <=> 6-Oxo-2-hydroxy-7-(4''-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7E-trienoate 1.13.11
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Theobromine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O 1.14.13.179 methylxanthine N3-demethylase
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n-butane + NADH + O2 + H+ <=> 1-butanol + NAD+ + H2O 1.14.13.230 butane monooxygenase (soluble)
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oxaloacetate + ATP <=> CO2 + phosphoenolpyruvate + ADP 4.1.1.31 phosphoenolpyruvate carboxylase
4.1.1.38 phosphoenolpyruvate carboxykinase (diphosphate)
4.1.1.49 phosphoenolpyruvate carboxykinase (ATP)
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succinate + NAD+ <=> fumarate + NADH + H+ 1.3.1.6 fumarate reductase (NADH)
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NADP+ + H2O + L-glutamate <=> NADPH + 2-oxoglutarate + NH3 + H+ 1.4.1.13 glutamate synthase (NADPH)
1.4.1.2 glutamate dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
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3,5-Dichloro-2-methylmuconolactone <=> 3-chloro-2-methyl-dienelactone + Cl- + H+ 4.5.1
5.5.1.7 chloromuconate cycloisomerase
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L-lysine <=> (3R)-3-methyl-D-ornithine 5.4.99.58 methylornithine synthase
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(R)-2-methylmalonyl-CoA <=> succinyl-CoA 5.4.99.2 methylmalonyl-CoA mutase
5.4.99.63 ethylmalonyl-CoA mutase
5.4.99.64 2-hydroxyisobutanoyl-CoA mutase
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2 deisopropylatrazine + O2 <=> 2 2-chloro-4,6-diamino-s-triazine + 2 acetaldehyde 1.14.15
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4-sulfomuconolactone + H2O <=> maleylacetate + sulfite + H+ 3.1.1.92 4-sulfomuconolactone hydrolase
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O2 + Vanillyl_alcohol <=> Vanillin + H2O2 1.1.3.38 vanillyl-alcohol oxidase
1.1.3.47 5-(hydroxymethyl)furfural oxidase
1.1.3.7 aryl-alcohol oxidase
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2-Pyrone-4,6-dicarboxylate + H2O <=> 4-oxalomesaconate + H+ 3.1.1.57 2-pyrone-4,6-dicarboxylate lactonase
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