|
|
Hydroxyspheroidene + 2 O2 + 4 reduced_ferredoxin + 4 H+ <=> Hydroxyspheroidenone + 3 H2O + 4 oxidized_ferredoxin
|
1.14.15.9
spheroidene monooxygenase
|
–
|
|
KEGG:
R07538
|
|
|
|
5-hydroxyisourate + H2O <=> 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
|
3.5.2.17
hydroxyisourate hydrolase
|
–
|
|
BRENDA:
BR48000
KEGG:
R06601
SABIO-RK:
6176
|
|
|
|
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 6-Methylsalicylate + CoA + CO2 + NADP+ + H2O
|
2.3.1.165
6-methylsalicylic-acid synthase
|
–
|
|
BRENDA:
BR44013
KEGG:
R07253
MetaCyc:
2.3.1.165-RXN
|
|
|
|
phosphoenolpyruvate + dihydroxyacetone <=> pyruvate + dihydroxyacetone_phosphate
|
2.7.1.121
phosphoenolpyruvate---glycerone phosphotransferase
|
–
|
|
BRENDA:
BR47735
KEGG:
R01012
MetaCyc:
2.7.1.121-RXN
SABIO-RK:
1304
|
|
|
|
ATP + lipoic_acid + glycine_cleavage_system_H <=> Lipoyl-protein + AMP + diphosphate
|
6.3.1.20
lipoate---protein ligase
|
–
|
|
KEGG:
R12433
|
|
|
|
H+ + pyruvate + phosphate + O2 <=> acetyl_phosphate + CO2 + H2O2
|
1.2.3.3
pyruvate oxidase
|
–
|
|
BRENDA:
BR36789
KEGG:
R00207
MetaCyc:
1.2.3.3-RXN
SABIO-RK:
167
|
|
|
|
n (3R)-hydroxybutyryl-CoA <=> poly(3-hydroxybutanoate)n + n CoA
|
2.3.1
|
–
|
|
KEGG:
R04254
|
|
|
|
N-acetylmuramate_6-phosphate + H2O <=> N-acetylmuramic_acid + phosphate
|
3.1.3.105
N-acetyl-D-muramate 6-phosphate phosphatase
|
–
|
|
BRENDA:
BR52180
KEGG:
R11785
MetaCyc:
RXN-18659
|
|
|
|
S-adenosyl-L-methionine + 5-hydroxyferulic_acid <=> H+ + Sinapic_acid + S-adenosyl-L-homocysteine
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
2.1.1.42
flavone 3'-O-methyltransferase
2.1.1.68
caffeate O-methyltransferase
|
–
–
–
|
|
BRENDA:
BS319577
KEGG:
R02379
MetaCyc:
RXN-3422
|
|
|
|
N,N''-diacetylchitobiose + phosphate <=> N-acetyl-D-glucosamine_1-phosphate + N-acetyl-D-glucosamine
|
2.4.1.280
N,N'-diacetylchitobiose phosphorylase
|
–
|
|
BRENDA:
BR49896
KEGG:
R09942
MetaCyc:
RXN-12627
|
|
|
|
3-Hydroxy-6,7,8-trimethoxy-2-naphthoate <=> 3-Hydroxy-7,8-dimethoxy-6-isopropoxy-2-naphthoate
|
not assigned
|
–
|
|
KEGG:
R11389
|
|
|
|
UDP-MurNAc-Ala-D-Glu-Lys + D-Ala-D-Ala + ATP <=> H+ + UDP-MurNAc-pentapeptide + phosphate + ADP
|
6.3.2.10
UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
6.3.2.4
D-alanine---D-alanine ligase
|
–
–
|
|
BRENDA:
BR102
KEGG:
R04573
MetaCyc:
6.3.2.10-RXN
SABIO-RK:
4244
|
|
|
|
salicylate + NADPH + H+ + O2 <=> 2,5-Dihydroxybenzoate + NADP+ + H2O
|
1.14.13.172
salicylate 5-hydroxylase
|
–
|
|
BRENDA:
BS422071
KEGG:
R07710
|
|
|
|
arachidonic_acid + O2 <=> 15-hydroperoxyeicosatetraenoic_acid
|
1.13.11.12
linoleate 13S-lipoxygenase
1.13.11.33
arachidonate 15-lipoxygenase
|
–
–
|
|
BRENDA:
BR47601
KEGG:
R01593
MetaCyc:
ARACHIDONATE-15-LIPOXYGENASE-RXN
SABIO-RK:
1742
|
|
|
|
dUTP + H2O <=> H+ + dUMP + diphosphate
|
3.6.1
3.6.1.23
dUTP diphosphatase
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
|
|
BRENDA:
BR22764
KEGG:
R02100
MetaCyc:
DUTP-PYROP-RXN
SABIO-RK:
365
|
|
|
|
3-methylthiopropionyl-CoA + FAD <=> 3-(methylthio)acryloyl-CoA + FADH2
|
1.3.8
|
–
|
|
KEGG:
R11130
|
|
|
|
P1,P4-bis(5''-guanosyl)_tetraphosphate + H2O <=> H+ + GTP + GMP
|
3.6.1.17
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
3.6.1.29
bis(5'-adenosyl)-triphosphatase
|
–
–
|
|
BRENDA:
BR22757
KEGG:
R01232
MetaCyc:
3.6.1.17-RXN
SABIO-RK:
300
|
|
|
|
NO + H2O + ferricytochrome_c <=> nitrite + ferricytochrome_c + 2 H+
|
1.7.2.1
nitrite reductase (NO-forming)
1.7.2.6
hydroxylamine dehydrogenase
|
–
–
|
|
BRENDA:
BR48041
KEGG:
R00783
|
|
|
|
3-(2,3-dihydroxyphenyl)propanoate + O2 <=> H+ + (2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate
|
1.13.11.16
3-carboxyethylcatechol 2,3-dioxygenase
|
–
|
|
BRENDA:
BR37079
KEGG:
R04376
MetaCyc:
1.13.11.16-RXN
SABIO-RK:
4072
|
|
|
|
S-adenosyl-L-methionine + 8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)-tetracenomycin_C <=> elloramycin + S-adenosyl-L-homocysteine + H+
|
2.1.1
|
–
|
|
KEGG:
R10959
MetaCyc:
RXN-15402
|
|
|
|
CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NAD+ + H2O <=> CDP-4-dehydro-6-deoxy-D-glucose + NADH + H+
|
1.17.1.1
CDP-4-dehydro-6-deoxyglucose reductase
|
–
|
|
BRENDA:
BR40372-a
KEGG:
R03391
MetaCyc:
1.17.1.1-RXN_WOP
|
|
|
|
(S)-allantoin + H2O <=> H+ + Allantoate
|
3.5.2.5
allantoinase
|
–
|
|
BRENDA:
BR26107
KEGG:
R02425
MetaCyc:
ALLANTOINASE-RXN
SABIO-RK:
2360
|
|
|
|
7-Oxoheptanoic_acid <=> 7-Mercaptoheptanoic_acid
|
not assigned
|
–
|
|
KEGG:
R10397
|
|
|
|
Guanidinoacetate + ATP <=> H+ + phosphoguanidinoacetate + ADP
|
2.7.3.1
guanidinoacetate kinase
2.7.3.2
creatine kinase
2.7.3.4
taurocyamine kinase
2.7.3.6
hypotaurocyamine kinase
|
–
–
–
–
|
|
BRENDA:
BR47831
KEGG:
R02575
MetaCyc:
GUANIDOACETATE-KINASE-RXN
|
|
|
|
6,8a-Seco-6,8a-deoxy-5-oxoavermectin_''''1a''''_aglycone + NADPH + O2 <=> 5-Oxoavermectin_''''1a''''_aglycone + NADP+ + H2O
|
1.14
|
–
|
|
KEGG:
R06467
|
|
|
|
alpha-D-ribose_1,5-bisphosphate + ATP <=> 5-phospho-alpha-D-ribose_1-diphosphate + ADP
|
2.7.4.23
ribose 1,5-bisphosphate phosphokinase
|
–
|
|
BRENDA:
BR48750;
BS384244
KEGG:
R06836
MetaCyc:
RXN0-1401
|
|
|
|
S-adenosyl-L-methionine + aklanonate <=> S-adenosyl-L-homocysteine + methyl_aklanonate
|
2.1.1.288
aklanonic acid methyltransferase
|
–
|
|
BRENDA:
BR50636
KEGG:
R06680
MetaCyc:
RXN-14831
|
|
|
|
Sinapic_acid + CoA + ATP <=> sinapoyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
|
–
|
|
BRENDA:
BS368951
KEGG:
R02221
MetaCyc:
RXN-10919
SABIO-RK:
2193
|
|
|
|
H2O + 4-Fumarylacetoacetate <=> H+ + fumarate + acetoacetate
|
3.7.1.2
fumarylacetoacetase
|
–
|
|
BRENDA:
BR29548
KEGG:
R01364
MetaCyc:
FUMARYLACETOACETASE-RXN
|
|
|
|
beta-Hydroxy-L-tyrosyl-[pcp] <=> beta-Keto-L-tyrosyl-[pcp]
|
not assigned
|
–
|
|
KEGG:
R06753
|
|
|
|
(S)-beta-Tyrosyl-[pcp] + FADH2 + Cl- + O2 + H+ <=> (S)-3-Chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
|
1.14.19
|
–
|
|
KEGG:
R11368
|
|
|
|
glycine + 2-oxoglutarate <=> glyoxylate + L-glutamate
|
2.6.1.2
alanine transaminase
2.6.1.4
glycine transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.48
5-aminovalerate transaminase
2.6.1.60
aromatic-amino-acid---glyoxylate transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR47690
KEGG:
R00372
MetaCyc:
GLYCINE-AMINOTRANSFERASE-RXN
SABIO-RK:
839
|
|
|
|
D-erythrose_4-phosphate + D-xylulose_5-phosphate <=> beta-D-fructose_6-phosphate + D-glyceraldehyde_3-phosphate
|
2.2.1.1
transketolase
2.2.1.3
formaldehyde transketolase
|
–
–
|
|
BRENDA:
BS320170;
BS320221;
BS434641
KEGG:
R01067;
R01830
MetaCyc:
2TRANSKETO-RXN
SABIO-RK:
1337
|
|
|
|
CMP-N-acetylneuraminate + paragloboside <=> CMP + 3''-isoLM1
|
2.4.99.6
N-acetyllactosaminide alpha-2,3-sialyltransferase
|
–
|
|
KEGG:
R06153
|
|
|
|
spermidine + S-adenosylmethioninamine <=> H+ + spermine + S-methyl-5''-thioadenosine
|
2.5.1.104
N1-aminopropylagmatine synthase
2.5.1.16
spermidine synthase
2.5.1.22
spermine synthase
2.5.1.23
sym-norspermidine synthase
2.5.1.79
thermospermine synthase
|
–
–
–
–
–
|
|
BRENDA:
BR44280
KEGG:
R02869
MetaCyc:
SPERMINE-SYNTHASE-RXN
SABIO-RK:
2733
|
|
|
|
Premithramycin_A3 + dTDP-D-boivinose <=> 3A-Deolivosylpremithramycin_B + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R09351
MetaCyc:
RXN-13380
|
|
|
|
cellooligomers + H2O <=> cellobiose + H2O
|
3.2.1.176
cellulose 1,4-beta-cellobiosidase (reducing end)
3.2.1.4
cellulase
3.2.1.91
cellulose 1,4-beta-cellobiosidase (non-reducing end)
|
–
–
–
|
|
BRENDA:
BS259935
KEGG:
R11308
|
|
|
|
UDP-glucose + alpha-D-glucose_6-phosphate <=> UDP + alpha,alpha''-Trehalose_6-phosphate
|
2.4.1.15
alpha,alpha-trehalose-phosphate synthase (UDP-forming)
|
–
|
|
KEGG:
R02737
|
|
|
|
L-tryptophan + FADH2 + Cl- + O2 <=> 7-chloro-L-tryptophan + FAD + H2O
|
1.14.19.9
tryptophan 7-halogenase
|
–
|
|
BRENDA:
BR48866
KEGG:
R09570
MetaCyc:
RXN-10842
SABIO-RK:
14708
|
|
|
|
4-coumaroyl-CoA + NADPH + H+ <=> 4-coumaraldehyde + CoA + NADP+
|
1.2.1.44
cinnamoyl-CoA reductase
|
–
|
|
BRENDA:
BS189225;
BS388396
KEGG:
R01615
MetaCyc:
RXN-1101
SABIO-RK:
1760
|
|
|
|
OPC6-CoA + FAD <=> trans-2-Enoyl-OPC6-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
|
KEGG:
R07892
|
|
|
|
NAD+ + ATP <=> H+ + NADP+ + ADP
|
2.7.1.23
NAD+ kinase
|
–
|
|
BRENDA:
BR47763
KEGG:
R00104
MetaCyc:
NAD-KIN-RXN
SABIO-RK:
47
|
|
|
|
IMP + diphosphate <=> hypoxanthine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
|
BRENDA:
BR47537
KEGG:
R01132
MetaCyc:
HYPOXANPRIBOSYLTRAN-RXN
SABIO-RK:
81
|
|
|
|
delta-tocotrienol <=> 6-geranylgeranyl-2-methylbenzene-1,4-diol
|
5.5.1.24
tocopherol cyclase
|
–
|
|
BRENDA:
BR50793
KEGG:
R10623
MetaCyc:
RXN-14921
|
|
|
|
seleno-L-methionine + H2O <=> methylselenol + NH3 + 2-oxobutyrate
|
4.4.1.1
cystathionine gamma-lyase
4.4.1.11
methionine gamma-lyase
4.4.1.13
cysteine-S-conjugate beta-lyase
|
–
–
–
|
|
BRENDA:
BS368491
KEGG:
R04770
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-[beta-D-GlcNAc-(1->4)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.144
beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
–
|
|
KEGG:
R05986
|
|
|
|
L-cystine + glutathione <=> GSSG + L-cysteine
|
1.8.1.6
cystine reductase
1.8.4.4
glutathione---cystine transhydrogenase
1.8.4.9
adenylyl-sulfate reductase (glutathione)
|
–
–
–
|
|
BRENDA:
BR37026
KEGG:
R01109;
R01113
MetaCyc:
1.8.4.4-RXN
|
|
|
|
dopamine + O2 + ascorbate + H+ <=> norepinephrine + ascorbate + H2O
|
1.14.17.1
dopamine beta-monooxygenase
|
–
|
|
BRENDA:
BR40401
KEGG:
R02535
MetaCyc:
DOPAMINE-BETA-MONOOXYGENASE-RXN
|
|
|
|
UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate + D-Ala-D-Ala + ATP <=> H+ + UDP-N-acetylmuramoyl-pentapeptide + phosphate + ADP
|
6.3.2.10
UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
|
–
|
|
KEGG:
R04617
MetaCyc:
UDP-NACMURALGLDAPAALIG-RXN
SABIO-RK:
4284
|
|
|
|
H+ + o-Cresol + NADH + O2 <=> 3-methylcatechol + NAD+ + H2O
|
1.14.13.236
toluene 4-monooxygenase
1.14.13.243
toluene 2-monooxygenase
1.14.13.44
2-hydroxybiphenyl 3-monooxygenase
1.14.13.7
phenol 2-monooxygenase (NADPH)
|
–
–
–
–
|
|
BRENDA:
BR52670
KEGG:
R03608
MetaCyc:
O-CRESOL-METHYLCATECHOL-RXN
|
|
|
|
1,6-dihydroxy-5-methylcyclohexa-2,4-dienecarboxylate + NAD+ <=> 3-methylcatechol + CO2 + NADH + H+
|
1.3.1
|
–
|
|
KEGG:
R05309
|
|
|
|
L-serine <=> D-serine
|
4.3.1.17
L-serine ammonia-lyase
5.1.1.1
alanine racemase
5.1.1.10
amino-acid racemase
5.1.1.18
serine racemase
|
–
–
–
–
|
|
BRENDA:
BR48732
KEGG:
R00589
MetaCyc:
5.1.1.18-RXN
SABIO-RK:
988
|
|
|
|
9-cis-violaxanthin <=> 9''-cis-Neoxanthin
|
5.3.99.9
neoxanthin synthase
|
–
|
|
KEGG:
R06951
|
|
|
|
CTP + phosphocholine + H+ <=> CDP-choline + diphosphate
|
2.7.7.15
choline-phosphate cytidylyltransferase
2.7.7.57
N-methylphosphoethanolamine cytidylyltransferase
|
–
–
|
|
BRENDA:
BR47864
KEGG:
R01890
MetaCyc:
2.7.7.15-RXN
SABIO-RK:
1949
|
|
|
|
oxaloacetate + ITP <=> CO2 + phosphoenolpyruvate + IDP
|
4.1.1.32
phosphoenolpyruvate carboxykinase (GTP)
4.1.1.49
phosphoenolpyruvate carboxykinase (ATP)
|
–
–
|
|
BRENDA:
BS1402
KEGG:
R00726
MetaCyc:
RXN-12481
SABIO-RK:
583
|
|
|
|
(3S)-3-carboxy-3-hydroxypropanoyl-CoA <=> glyoxylate + acetyl-CoA
|
4.1.3.24
malyl-CoA lyase
|
–
|
|
BRENDA:
BR3371;
BS444081
KEGG:
R00473
MetaCyc:
MALYL-COA-LYASE-RXN
|
|
|
|
H2O + hippuric_acid <=> glycine + benzoate
|
3.4.17.B1
3.5.1.32
hippurate hydrolase
3.5.1.71
N-feruloylglycine deacylase
|
–
–
–
|
|
BRENDA:
BR19245
KEGG:
R01424
MetaCyc:
HIPPURATE-HYDROLASE-RXN
|
|
|
|
Prostaglandin_B2 <=> Prostaglandin_C2
|
not assigned
|
–
|
|
KEGG:
R05057
|
|
|
|
O2 + arachidonic_acid <=> (5Z,9E,11Z,14Z)-(8S)-8-hydroperoxyeicosa-5,9,11,14-tetraenoate
|
1.13.11
1.13.11.40
arachidonate 8-lipoxygenase
|
–
–
|
|
BRENDA:
BS375051
KEGG:
R07053
MetaCyc:
ARACHIDONATE-8-LIPOXYGENASE-RXN
|
|
|
|
dUMP + 5,10-methylenetetrahydrofolate + NADPH + H+ <=> dTMP + tetrahydrofolate + NADP+
|
1.5.1.3
dihydrofolate reductase
2.1.1.148
thymidylate synthase (FAD)
|
–
–
|
|
BRENDA:
BR47450
KEGG:
R06613
MetaCyc:
RXN-8850
SABIO-RK:
7840
|
|
|
|
UDP-galactose + GD2-ganglioside <=> UDP + GD1b
|
2.4.1.62
ganglioside galactosyltransferase
|
–
|
|
BRENDA:
BS322866
KEGG:
R05110;
R05948
|
|
|
|
glutathione + glutathionylspermidine + ATP <=> H+ + trypanothione + ADP + phosphate
|
6.3.1.9
trypanothione synthase
|
–
|
|
BRENDA:
BR48737;
BS427492
KEGG:
R03822
MetaCyc:
6.3.1.9-RXN
SABIO-RK:
3578
|
|
|
|
paraxanthine <=> 1-Methylxanthine
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
KEGG:
R07943
|
|
|
|
CoA + heptanedioate + ATP <=> pimeloyl-CoA + diphosphate + AMP
|
6.2.1.14
6-carboxyhexanoate---CoA ligase
6.2.1.23
dicarboxylate---CoA ligase
|
–
–
|
|
BRENDA:
BR65
KEGG:
R03209
MetaCyc:
6-CARBOXYHEXANOATE--COA-LIGASE-RXN
|
|
|
|
dTDP-4-oxo-2,6-dideoxy-D-allose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
|
5.1.3
|
–
|
|
KEGG:
R06433
|
|
|
|
ATP + L-rhamnulose <=> ADP + L-rhamnulose_1-phosphate
|
2.7.1.5
rhamnulokinase
|
–
|
|
BRENDA:
BR47784
KEGG:
R03014
SABIO-RK:
2864
|
|
|
|
L-phenylalanine + tetrahydrobiopterin + O2 <=> L-tyrosine + 4a-hydroxytetrahydrobiopterin
|
1.14.16.1
phenylalanine 4-monooxygenase
|
–
|
|
BRENDA:
BS386541
KEGG:
R07211
SABIO-RK:
8496
|
|
|
|
2-epi-5-epi-valiolone <=> 5-epi-valiolone
|
5.1.3.33
2-epi-5-epi-valiolone epimerase
|
–
|
|
BRENDA:
BR51250
KEGG:
R11079
MetaCyc:
RXN-9141
|
|
|
|
cholesterol + NADP+ <=> desmosterol + NADPH + H+
|
1.3.1.72
Delta24-sterol reductase
|
–
|
|
BRENDA:
BS189401
KEGG:
R01457
MetaCyc:
RXN66-28
|
|
|
|
S-hydroxymethylglutathione + NAD+ <=> S-formylglutathione + NADH + H+
|
1.1.1
1.1.1.1
alcohol dehydrogenase
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
1.2.1.46
formaldehyde dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BR48484-a
KEGG:
R06983
MetaCyc:
RXN-2962_WOP;
RXN0-276
SABIO-RK:
7489
|
|
|
|
UDP-galactose + GT2 <=> UDP + GT1c
|
2.4.1.62
ganglioside galactosyltransferase
|
–
|
|
KEGG:
R05953
|
|
|
|
2-hydro-1,2-dihydroxybenzoate + NAD+ <=> catechol + CO2 + NADH
|
1.3.1.25
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
|
–
|
|
BRENDA:
BR48039;
BS359444
KEGG:
R00813
MetaCyc:
1.3.1.25-RXN
|
|
|
|
L-3-hydroxydodecanoyl-CoA + NAD+ <=> 3-oxododecanoyl-CoA + NADH + H+
|
1.1.1.211
long-chain-3-hydroxyacyl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
KEGG:
R04741
MetaCyc:
RXN-20676
|
|
|
|
D-ribose_5-phosphate <=> D-ribulose_5-phosphate
|
5.3.1.6
ribose-5-phosphate isomerase
|
–
|
|
BRENDA:
BR237
KEGG:
R01056
MetaCyc:
RIB5PISOM-RXN
|
|
|
|
ATP + D-mannoheptulose <=> ADP + sedoheptulose_7-phosphate + H+
|
2.7.1.14
sedoheptulokinase
|
–
|
|
BRENDA:
BR47439
KEGG:
R01844
MetaCyc:
SEDOHEPTULOKINASE-RXN
|
|
|
|
S-adenosyl-L-methionine + 3,4-dihydroxyphenylglycol <=> S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxyphenylglycol
|
2.1.1.6
catechol O-methyltransferase
|
–
|
|
KEGG:
R04881
|
|
|
|
bilirubin + coenzyme_F420-1 <=> Biliverdin + Reduced_coenzyme_F420-(gamma-Glu)n
|
1.3.98
|
–
|
|
KEGG:
R12481
|
|
|
|
Sulfide + NADP+ + H2O <=> sulfite + NADPH + H+
|
1.8.1.2
assimilatory sulfite reductase (NADPH)
|
–
|
|
BRENDA:
BR36931
KEGG:
R00858
MetaCyc:
SULFITE-REDUCT-RXN
|
|
|
|
H+ + 6,7-dimethyl-8-(1'-D-ribityl)lumazine <=> 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + riboflavin
|
2.5.1.9
riboflavin synthase
|
–
|
|
BRENDA:
BR47473
KEGG:
R00066
MetaCyc:
RIBOFLAVIN-SYN-RXN
SABIO-RK:
653
|
|
|
|
cholesterol + reduced_flavodoxin + O2 <=> 7alpha-hydroxycholesterol + flavin + H2O
|
1.14.14.23
cholesterol 7alpha-monooxygenase
|
–
|
|
BRENDA:
BR29138
KEGG:
R01463
|
|
|
|
NAD+ + (1S,2R)-3-Methylcyclohexa-3,5-diene-1,2-diol <=> H+ + NADH + 3-methylcatechol
|
1.3.1.19
cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
|
–
|
|
KEGG:
R04088
MetaCyc:
TOLUENE-DIOL-DEHYDROGENASE-RXN
|
|
|
|
dehydroascorbate + H2O <=> (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate
|
0.0.0.0
3.1.1.17
gluconolactonase
|
–
–
|
|
BRENDA:
BR52869
KEGG:
R04785
MetaCyc:
RXN-21400
|
|
|
|
9-fluorenone + NADH + H+ + O2 <=> 1,1a-dihydroxy-1-hydrofluoren-9-one + NAD+
|
1.14.12
1.14.12.22
carbazole 1,9a-dioxygenase
|
–
–
|
|
BRENDA:
BS411441-a
KEGG:
R07799
|
|
|
|
L-2-methyl-3-oxopropionate + CoA + NAD+ <=> propionyl-CoA + CO2 + NADH + H+
|
1.2.1.27
methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
|
–
|
|
KEGG:
R00935
SABIO-RK:
1253
|
|
|
|
campesterol <=> Campest-4-en-3beta-ol
|
5.3.3.1
steroid Delta-isomerase
|
–
|
|
KEGG:
R07427
MetaCyc:
RXN-709
|
|
|
|
ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate <=> H+ + ADP + phosphate + 5''-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole
|
6.3.2.6
phosphoribosylaminoimidazolesuccinocarboxamide synthase
|
–
|
|
BRENDA:
BR122
KEGG:
R04591
MetaCyc:
SAICARSYN-RXN
|
|
|
|
formate + GTP + H+ <=> dGTP + CO2 + H2O
|
1.1.98.6
ribonucleoside-triphosphate reductase (formate)
|
–
|
|
BRENDA:
BS439595
KEGG:
R11633
MetaCyc:
RXN0-746
|
|
|
|
sedoheptulose_1,7-diphosphate <=> dihydroxyacetone_phosphate + D-erythrose_4-phosphate
|
4.1.2.13
fructose-bisphosphate aldolase
|
–
|
|
BRENDA:
BS1655
KEGG:
R01829
MetaCyc:
SEDOBISALDOL-RXN
SABIO-RK:
45
|
|
|
|
CDP-diacylglycerol + sn-glycerol_3-phosphate <=> CMP + 1-(3-sn-phosphatidyl)-sn-glycerol_3-phosphate + H+
|
2.7.8.5
CDP-diacylglycerol---glycerol-3-phosphate 1-phosphatidyltransferase
2.7.8.8
CDP-diacylglycerol---serine O-phosphatidyltransferase
|
–
–
|
|
BRENDA:
BR47986;
BS358731
KEGG:
R01801
MetaCyc:
PHOSPHAGLYPSYN-RXN
|
|
|
|
mesaconate + CoA <=> 2-methylfumaryl-CoA + H2O
|
not assigned
|
–
|
|
KEGG:
R03695
|
|
|
|
xylene + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> 3-methylbenzyl_alcohol + oxidized_ferredoxin + H2O
|
1.14.15.26
toluene methyl-monooxygenase
|
–
|
|
BRENDA:
BR52310
KEGG:
R05443
MetaCyc:
RXN-8578
|
|
|
|
10-deoxymethymycin + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> methymycin + oxidized_ferredoxin + H2O
|
1.14.15.33
pikromycin synthase
|
–
|
|
BRENDA:
BR50920
KEGG:
R06463
MetaCyc:
RXN-15100
|
|
|
|
adenosine_3''-monophosphate + H2O <=> adenosine + phosphate
|
3.1.21.1
deoxyribonuclease I
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.25
inositol-phosphate phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.6
3'-nucleotidase
3.1.30.1
Aspergillus nuclease S1
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.6.1.1
inorganic diphosphatase
3.6.1.11
exopolyphosphatase
|
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS364421
KEGG:
R01562
MetaCyc:
RXN-14126
SABIO-RK:
305
|
|
|
|
7,8-dihydroneopterin_2,3''-cyclic_phosphate + H2O <=> H+ + 7,8-dihydroneopterin_2''-phosphate
|
3.1.4.56
7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase
|
–
|
|
BRENDA:
BR50444
KEGG:
R10345
MetaCyc:
RXN-12357
|
|
|
|
ent-kaur-16-en-19-oate + reduced_flavodoxin + O2 <=> ent-7alpha-hydroxykaur-16-en-19-oate + flavin + H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
|
BRENDA:
BR40543
KEGG:
R06294
|
|
|
|
4 2-imino-3-(7-chloroindol-3-yl)propanoate + O2 <=> 2 dichlorochromopyrrolate + 2 NH3 + 2 H2O
|
1.21.98.2
dichlorochromopyrrolate synthase
|
–
|
|
BRENDA:
BS402313
KEGG:
R09566
|
|
|
|
heme + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> Biliverdin + Fe2+ + CO + oxidized_ferredoxin + H2O
|
1.14.15.20
heme oxygenase (biliverdin-producing, ferredoxin)
|
–
|
|
BRENDA:
BR51703
KEGG:
R11579
MetaCyc:
RXN-17523
|
|
|
|
ergothioneine <=> Thiourocanic_acid + trimethylamine
|
not assigned
|
–
|
|
KEGG:
R04877
|
|
|
|
sitosterol + NADPH + H+ + O2 <=> stigmasterol + NADP+ + H2O
|
1.14.19.41
sterol 22-desaturase
|
–
|
|
BRENDA:
BS432714
KEGG:
R07489
|
|
|
|
Sulfide + oxidized_ferredoxin + H2O <=> sulfite + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.8.7.1
assimilatory sulfite reductase (ferredoxin)
|
–
|
|
BRENDA:
BR40346
KEGG:
R00859
MetaCyc:
SULFITE-REDUCTASE-FERREDOXIN-RXN
SABIO-RK:
1195
|
|
|
|
L-glutamate + L-cysteine + ATP <=> gamma-Glu-L-Cys + ADP + phosphate + H+
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
|
BRENDA:
BR112
KEGG:
R00894
MetaCyc:
GLUTCYSLIG-RXN
SABIO-RK:
1217
|
|
|
|
UDP-D-xylose + protein <=> D-xylosylprotein + UDP + H+
|
2.4.2.26
protein xylosyltransferase
2.4.2.63
EGF-domain serine xylosyltransferase
|
–
–
|
|
KEGG:
R05925
MetaCyc:
2.4.2.26-RXN
|
|
|
|
Nomega-hydroxy-L-arginine + NADPH + O2 <=> L-citrulline + NO + NADP+ + H2O + H+
|
1.14.13.39
nitric-oxide synthase (NADPH)
|
–
|
|
BRENDA:
BR50160;
BS289236
KEGG:
R00111
MetaCyc:
RXN-13565
|
|
|
|
malonyl-CoA + [acyl-carrier_protein] <=> CoA + malonyl-[acyl-carrier_protein]
|
2.3.1
2.3.1.39
[acyl-carrier-protein] S-malonyltransferase
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
–
–
|
|
BRENDA:
BR44039
KEGG:
R01626
MetaCyc:
MALONYL-COA-ACP-TRANSACYL-RXN
SABIO-RK:
1767
|
|
|
|
S-adenosyl-L-methionine + (8S)-8-amino-7-oxononanoate <=> S-adenosyl-4-methylthio-2-oxobutanoate + (7R,8S)-diaminononanoate
|
2.3.1.47
8-amino-7-oxononanoate synthase
2.6.1.62
adenosylmethionine---8-amino-7-oxononanoate transaminase
|
–
–
|
|
BRENDA:
BR47441;
BS406980
KEGG:
R03231
MetaCyc:
DAPASYN-RXN
SABIO-RK:
3057
|
|
|
|
H+ + alpha-D-glucose_1-phosphate + GTP <=> GDP-glucose + diphosphate
|
2.7.7.13
mannose-1-phosphate guanylyltransferase
2.7.7.24
glucose-1-phosphate thymidylyltransferase
2.7.7.28
nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase
2.7.7.30
fucose-1-phosphate guanylyltransferase
2.7.7.34
glucose-1-phosphate guanylyltransferase
2.7.7.9
UTP---glucose-1-phosphate uridylyltransferase
|
–
–
–
–
–
–
|
|
BRENDA:
BR47880;
BS358355
KEGG:
R00954
MetaCyc:
2.7.7.34-RXN
SABIO-RK:
1267
|
|
|
|
beta-D-glucose_6-phosphate <=> beta-D-fructose_6-phosphate
|
5.3.1.9
glucose-6-phosphate isomerase
|
–
|
|
KEGG:
R03321
|
|
|
|
GDP-mannose + 2-O-(alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol <=> 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol + GDP + H+
|
2.4.1.346
phosphatidyl-myo-inositol dimannoside synthase
|
–
|
|
BRENDA:
BR52637
KEGG:
R11703;
R12040
MetaCyc:
RXN-18607
|
|
|
|
crocetin_dialdehyde <=> crocetin
|
not assigned
|
–
|
|
KEGG:
R12135
|
|
|
|
Fumiquinazoline_F + 3 reduced_flavodoxin + 2 O2 <=> Fumiquinazoline_F-indoline-2'',3''-diol + 3 flavin + 2 H2O
|
1.14.14
|
–
|
|
KEGG:
R12418
|
|
|
|
2-tetradecenoyl-CoA + NADPH <=> myristoyl-CoA + NADP+
|
1.3.1.38
trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BS258642
KEGG:
R03989
|
|
|
|
NH3 + NADP+ + H2O <=> nitrite + NADPH + H+
|
1.7.1.4
nitrite reductase [NAD(P)H]
1.7.7.1
ferredoxin---nitrite reductase
1.8.1.2
assimilatory sulfite reductase (NADPH)
|
–
–
–
|
|
BRENDA:
BR36928
KEGG:
R00789
MetaCyc:
RXN0-6377
|
|
|
|
ATP + D-Fructose_1-phosphate <=> H+ + ADP + D-fructose_1,6-bisphosphate
|
2.7.1.11
6-phosphofructokinase
2.7.1.56
1-phosphofructokinase
|
–
–
|
|
BRENDA:
BR47787
KEGG:
R02071
MetaCyc:
1PFRUCTPHOSN-RXN
|
|
|
|
5-Aminopentanamide + H2O <=> 5-Aminopentanoate + NH3
|
3.5.1.30
5-aminopentanamidase
|
–
|
|
BRENDA:
BR19244
KEGG:
R02273
MetaCyc:
5-AMINOPENTANAMIDASE-RXN
|
|
|
|
UDP-glucose + beta-D-fructose_6-phosphate <=> sucrose_6F-phosphate + UDP + H+
|
2.4.1.13
sucrose synthase
2.4.1.14
sucrose-phosphate synthase
|
–
–
|
|
BRENDA:
BR47559;
BS355460
KEGG:
R00766;
R06073
MetaCyc:
SUCROSE-PHOSPHATE-SYNTHASE-RXN
SABIO-RK:
8678
|
|
|
|
L-threo-3-methylaspartate <=> NH3 + mesaconate
|
4.3.1.2
methylaspartate ammonia-lyase
|
–
|
|
BRENDA:
BR487
KEGG:
R03696
MetaCyc:
METHYLASPARTATE-AMMONIA-LYASE-RXN
|
|
|
|
L-4-hydroxyglutamate_semialdehyde + NAD+ + H2O <=> L-erythro-4-hydroxyglutamate + NADH + H+
|
1.2.1
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
|
–
–
|
|
KEGG:
R05051
MetaCyc:
RXN-14472
|
|
|
|
cocaine + H2O <=> H+ + methyl_ecgonine + benzoate
|
3.1.1.1
carboxylesterase
3.1.1.8
cholinesterase
3.1.1.84
cocaine esterase
|
–
–
–
|
|
BRENDA:
BR49194;
BS402273
KEGG:
R06728
MetaCyc:
RXN-11192
|
|
|
|
succinate_semialdehyde + NADP+ + CoA <=> succinyl-CoA + NADPH + H+
|
1.2.1.75
malonyl-CoA reductase (malonate semialdehyde-forming)
1.2.1.76
succinate-semialdehyde dehydrogenase (acylating)
|
–
–
|
|
BRENDA:
BR49114
KEGG:
R09280
MetaCyc:
RXN-8891
|
|
|
|
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoic_acid + ATP + CoA <=> trihydroxycoprostanoyl-CoA + AMP + diphosphate
|
6.2.1.7
cholate---CoA ligase
|
–
|
|
BRENDA:
BS363620
KEGG:
R04580;
R08733
MetaCyc:
6.2.1.29-RXN
SABIO-RK:
4251
|
|
|
|
1-phosphatidyl-1D-myo-inositol_5-phosphate + ATP <=> phosphatidylinositol_4,5-bisphosphate + ADP + H+
|
2.7.1.149
1-phosphatidylinositol-5-phosphate 4-kinase
2.7.1.68
1-phosphatidylinositol-4-phosphate 5-kinase
|
–
–
|
|
BRENDA:
BR36935
KEGG:
R05803
MetaCyc:
2.7.1.149-RXN
SABIO-RK:
5394
|
|
|
|
tetrachlorohydroquinone + NAD+ + H+ <=> tetrafluoro-1,4-benzoquinone + NADH
|
1.1.1.404
tetrachlorobenzoquinone reductase
|
–
|
|
BRENDA:
BR51917
KEGG:
R11585
MetaCyc:
RXN-18404
|
|
|
|
eriodictyol <=> 2',3,4,4',6'-pentahydroxychalcone
|
5.5.1.6
chalcone isomerase
|
–
|
|
BRENDA:
BS430162
KEGG:
R07991
|
|
|
|
scyllo-inosose <=> H2O + 3D-3,5/4-trihydroxycyclohexa-1,2-dione
|
4.2.1.44
myo-inosose-2 dehydratase
|
–
|
|
BRENDA:
BR423;
BS1987
KEGG:
R02782;
R05659
MetaCyc:
MYO-INOSOSE-2-DEHYDRATASE-RXN
|
|
|
|
cellotriose + H2O <=> cellobiose + D-glucose
|
3.2.1.151
xyloglucan-specific endo-beta-1,4-glucanase
3.2.1.176
cellulose 1,4-beta-cellobiosidase (reducing end)
3.2.1.21
beta-glucosidase
3.2.1.25
beta-mannosidase
3.2.1.39
glucan endo-1,3-beta-D-glucosidase
3.2.1.4
cellulase
3.2.1.73
licheninase
3.2.1.74
glucan 1,4-beta-glucosidase
3.2.1.91
cellulose 1,4-beta-cellobiosidase (non-reducing end)
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS259927;
BS372652;
BS372661;
BS392069
KEGG:
R01444;
R02887;
R06105
SABIO-RK:
1626
|
|
|
|
myo-inositol + O2 <=> D-glucuronate + H2O
|
1.13.99.1
inositol oxygenase
|
–
|
|
BRENDA:
BR570
KEGG:
R01184
|
|
|
|
H+ + sulfate + ATP <=> adenosine_5''-phosphosulfate + diphosphate
|
2.7.7.4
sulfate adenylyltransferase
|
–
|
|
BRENDA:
BR47884
KEGG:
R00529
MetaCyc:
SULFATE-ADENYLYLTRANS-RXN
SABIO-RK:
947
|
|
|
|
dATP + thioredoxin_disulfide + H2O <=> ATP + thioredoxin
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
|
BRENDA:
BS287787
KEGG:
R02014
MetaCyc:
RXN-21262
SABIO-RK:
2051
|
|
|
|
D-glucosamine + D-Glucosaminide <=> D-Glucosaminide + H2O
|
3.2.1.165
exo-1,4-beta-D-glucosaminidase
|
–
|
|
KEGG:
R01966
|
|
|
|
ATP + NH3 + CO2 + H2O <=> ADP + phosphate + Carbamoyl_phosphate
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
|
BRENDA:
BS369145
KEGG:
R00149
SABIO-RK:
715
|
|
|
|
H+ + 5-guanidino-2-oxopentanoate <=> CO2 + 4-guanidinobutyraldehyde
|
4.1.1.75
5-guanidino-2-oxopentanoate decarboxylase
|
–
|
|
BRENDA:
BR336
KEGG:
R03178
MetaCyc:
4.1.1.75-RXN
|
|
|
|
S-adenosyl-L-methionine + 24(28)-methylene_lophenol <=> H+ + 24-ethylidenelophenol + S-adenosyl-L-homocysteine
|
2.1.1.142
cycloartenol 24-C-methyltransferase
2.1.1.143
24-methylenesterol C-methyltransferase
2.1.1.41
sterol 24-C-methyltransferase
|
–
–
–
|
|
BRENDA:
BR33800
KEGG:
R05776
MetaCyc:
2.1.1.143-RXN
SABIO-RK:
5368
|
|
|
|
dihydrolipoylprotein + Lipoyl-carrier_protein_E2 <=> glycine_cleavage_system_H + enzyme_N6-(dihydrolipoyl)lysine
|
not assigned
|
–
|
|
KEGG:
R12432
|
|
|
|
8-O-methyldihydrosterigmatocystin <=> Aflatoxin_G2
|
not assigned
|
–
|
|
KEGG:
R10482
MetaCyc:
RXN-9503
|
|
|
|
octanoyl-[acyl-carrier_protein] + NADP+ <=> 2-octenoyl-[acyl-carrier_protein] + NADPH + H+
|
1.3.1
1.3.1.10
enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104
enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39
enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
–
–
–
–
|
|
KEGG:
R04959
MetaCyc:
RXN-9526
|
|
|
|
24(28)-methylene_lophenol <=> 4alpha-methyl-5alpha-ergosta-8,24-dien-3beta-ol
|
5.3.3.5
cholestenol Delta-isomerase
|
–
|
|
BRENDA:
BS418315
KEGG:
R07484
MetaCyc:
RXN-4161
|
|
|
|
4a-hydroxytetrahydrobiopterin <=> dihydrobiopterin + H2O
|
4.2.1.96
4a-hydroxytetrahydrobiopterin dehydratase
|
–
|
|
BRENDA:
BR468;
BS2138
KEGG:
R04734
|
|
|
|
[protein]-L-asparagine + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_diphosphate + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.99.18
dolichyl-diphosphooligosaccharide---protein glycotransferase
|
–
|
|
KEGG:
R05976
|
|
|
|
H+ + 2-aminoacrylate + H2O <=> malonate_semialdehyde + NH3
|
3.5.1
|
–
|
|
KEGG:
R09983
MetaCyc:
RXN0-6452
|
|
|
|
D-glucuronolactone + H2O <=> D-glucuronate + H+
|
3.1.1
3.1.1.19
uronolactonase
|
–
–
|
|
KEGG:
R01483
MetaCyc:
RXN-14202
|
|
|
|
L-arogenate + oxaloacetate <=> prephenate + L-aspartate
|
2.6.1.1
aspartate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.78
aspartate---prephenate aminotransferase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
|
|
BRENDA:
BR48629
KEGG:
R01731
MetaCyc:
PREPHENATE-ASP-TRANSAMINE-RXN
SABIO-RK:
1841
|
|
|
|
D-xylose + NADP+ <=> D-xylono-1,5-lactone + NADPH + H+
|
1.1.1.179
D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359
aldose 1-dehydrogenase [NAD(P)+]
1.1.1.376
L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.424
D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
1.1.1.47
glucose 1-dehydrogenase [NAD(P)+]
1.1.1.B35
|
–
–
–
–
–
–
|
|
BRENDA:
BR29238
KEGG:
R01430
MetaCyc:
D-XYLOSE-1-DEHYDROGENASE-NADP+-RXN;
RXN-14641
SABIO-RK:
1615
|
|
|
|
ATP + (S)-beta-tyrosine + pC3'p <=> AMP + diphosphate + (S)-beta-Tyrosyl-[pcp]
|
6.2.1
|
–
|
|
KEGG:
R11367
|
|
|
|
3-Hydroxyanthranilate + O2 <=> alpha-amino-beta-carboxymuconate-epsilon-semialdehyde
|
1.13.11.6
3-hydroxyanthranilate 3,4-dioxygenase
|
–
|
|
BRENDA:
BR40468
KEGG:
R02665
MetaCyc:
1.13.11.6-RXN
SABIO-RK:
2561
|
|
|
|
7-hydroxychlorophyllide_a + NADP+ <=> chlorophyllide_b + NADPH + H+
|
1.1.1.294
chlorophyll(ide) b reductase
|
–
|
|
BRENDA:
BR48851
KEGG:
R08915
|
|
|
|
H+ + H2O + 1-pyrroline-4-hydroxy-2-carboxylate <=> NH3 + 2,5-dioxopentanoate
|
3.5.4.22
1-pyrroline-4-hydroxy-2-carboxylate deaminase
|
–
|
|
BRENDA:
BR26116
KEGG:
R02280
MetaCyc:
3.5.4.22-RXN
|
|
|
|
cyclo-L-Trp-L-Phe + S-adenosyl-L-methionine <=> N-Methyl-cyclo(L-Trp-L-Phe) + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R12414
|
|
|
|
1,4-dihydroxy-2-naphthoyl-CoA + H2O <=> H+ + 1,4-dihydroxy-2-naphthoate + CoA
|
3.1.2.28
1,4-dihydroxy-2-naphthoyl-CoA hydrolase
|
–
|
|
BRENDA:
BR49261
KEGG:
R07262
MetaCyc:
RXN-9311
|
|
|
|
ATP + D-tagatose <=> ADP + D-tagatose_6-phosphate
|
2.7.1.101
tagatose kinase
|
–
|
|
BRENDA:
BR47715
KEGG:
R02927
|
|
|
|
RX + glutathione <=> acceptor + R-S-glutathione
|
2.5.1.18
glutathione transferase
2.5.1.75
tRNA dimethylallyltransferase
|
–
–
|
|
BRENDA:
BR47501
KEGG:
R03522
SABIO-RK:
3310
|
|
|
|
N-acetyl-L-citrulline + H2O <=> L-citrulline + acetate
|
3.5.1.16
acetylornithine deacetylase
3.5.1.B4
|
–
–
|
|
BRENDA:
BR48939;
BS394032
KEGG:
R09107
MetaCyc:
RXN-7933
|
|
|
|
cannabigerolate + O2 <=> DELTA9-tetrahydrocannabinolate + H2O2
|
1.21.3.7
tetrahydrocannabinolic acid synthase
|
–
|
|
BRENDA:
BR50269
KEGG:
R12101
MetaCyc:
RXN-7854
|
|
|
|
3-dehydro-6-deoxoteasterone <=> 6-deoxotyphasterol
|
not assigned
|
–
|
|
KEGG:
R07473
|
|
|
|
L-lactate + O2 <=> acetate + CO2 + H2O
|
1.13.12.4
lactate 2-monooxygenase
|
–
|
|
BRENDA:
BR40547
KEGG:
R00319
MetaCyc:
RXN-19631
|
|
|
|
thiamine + ATP <=> H+ + thiamine_diphosphate + AMP
|
2.7.6.2
thiamine diphosphokinase
|
–
|
|
BRENDA:
BR47855
KEGG:
R00619
MetaCyc:
THIAMIN-PYROPHOSPHOKINASE-RXN
|
|
|
|
6-carboxyhex-2-enoyl-CoA + H2O <=> 3-hydroxypimeloyl-CoA
|
4.2.1
|
–
|
|
KEGG:
R05601
MetaCyc:
RXN-8031
|
|
|
|
sucrose_6F-phosphate + H2O <=> sucrose + phosphate
|
3.1.3.24
sucrose-phosphate phosphatase
|
–
|
|
BRENDA:
BR12744
KEGG:
R00805;
R06211
MetaCyc:
SUCROSE-PHOSPHATASE-RXN
SABIO-RK:
1150
|
|
|
|
1,1a-dihydroxy-1-hydrofluoren-9-one + H2O <=> 2,3-Dihydroxy-2''-carboxybiphenyl + 2 H+
|
1.3
|
–
|
|
KEGG:
R07800
|
|
|
|
3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + ATP + CoA <=> 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA + AMP + diphosphate
|
6.2.1.41
3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate---CoA ligase
|
–
|
|
BRENDA:
BR51067
KEGG:
R10769
MetaCyc:
RXN-12746
|
|
|
|
gamma-L-glutamylputrescine + H2O + O2 <=> gamma-glutamyl-gamma-aminobutyraldehyde + H2O2 + NH3
|
1.4.3
1.4.3.B1
1.4.3.M3
|
–
–
–
|
|
BRENDA:
BR51104
KEGG:
R07415
MetaCyc:
RXN0-3921
|
|
|
|
ATP + NAD+ <=> H+ + 3''-dehydro-ATP + NADH
|
1
|
–
|
|
KEGG:
R05668
MetaCyc:
RXN-9444
|
|
|
|
3,5,7,9,11,13,15,17,19-Nonaoxo-eicosanoyl-[acp] <=> 7,12-Decaketide_intermediate_1 + H2O
|
4.2.1
|
–
|
|
KEGG:
R09268
|
|
|
|
XMP + H2O <=> Xanthosine + phosphate
|
3.1.3.5
5'-nucleotidase
|
–
|
|
BRENDA:
BS383410
KEGG:
R02719
MetaCyc:
XMPXAN-RXN
SABIO-RK:
129
|
|
|
|
Premithramycin_A1 + dTDP-D-oliose <=> Premithramycin_A2' + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R06717
MetaCyc:
RXN-13376
|
|
|
|
globotriosylceramide + H2O <=> lactosylceramide + D-galactose
|
3.2.1.22
alpha-galactosidase
3.2.1.47
galactosylgalactosylglucosylceramidase
|
–
–
|
|
BRENDA:
BR16005
KEGG:
R03618;
R05961
MetaCyc:
3.2.1.47-RXN
|
|
|
|
naringenin_chalcone <=> naringenin
|
5.5.1.6
chalcone isomerase
|
–
|
|
BRENDA:
BS380128
KEGG:
R02446
MetaCyc:
APIGNAR-RXN
SABIO-RK:
2380
|
|
|
|
D-fructose_1,6-bisphosphate <=> dihydroxyacetone_phosphate + D-glyceraldehyde_3-phosphate
|
4.1.2.13
fructose-bisphosphate aldolase
4.1.2.40
tagatose-bisphosphate aldolase
|
–
–
|
|
BRENDA:
BR344;
BS398846
KEGG:
R01068;
R01070
MetaCyc:
F16ALDOLASE-RXN
SABIO-RK:
1338;
3
|
|
|
|
S-adenosyl-L-methionine + 3,4-dihydroxymandelate <=> vanillylmandelic_acid + S-adenosyl-L-homocysteine + H+
|
2.1.1.6
catechol O-methyltransferase
|
–
|
|
KEGG:
R04887
MetaCyc:
RXN-10916
|
|
|
|
2,4,5-trichloro-2,5-cyclohexadiene-1-ol + H2O <=> 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + Hydrochloric_acid
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
KEGG:
R05370
|
|
|
|
NAD+ + L-gulonate <=> H+ + NADH + 3-dehydro-L-gulonate
|
1.1.1.45
L-gulonate 3-dehydrogenase
|
–
|
|
BRENDA:
BR29308
KEGG:
R02640
MetaCyc:
L-GULONATE-3-DEHYDROGENASE-RXN
SABIO-RK:
2539
|
|
|
|
L-tryptophan + L-proline + 2 ATP <=> brevianamide_F + 2 AMP + 2 diphosphate
|
not assigned
|
–
|
|
KEGG:
R10661
|
|
|
|
D-xylonate <=> H2O + 2-dehydro-3-deoxy-D-xylonate
|
4.2.1.82
xylonate dehydratase
|
–
|
|
BRENDA:
BR48370
KEGG:
R02429
MetaCyc:
XYLONATE-DEHYDRATASE-RXN
SABIO-RK:
2364
|
|
|
|
D-fructose_1,6-bisphosphate + H2O <=> beta-D-fructose_6-phosphate + phosphate
|
3.1.3.11
fructose-bisphosphatase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.37
sedoheptulose-bisphosphatase
3.1.3.7
3'(2'),5'-bisphosphate nucleotidase
|
–
–
–
–
|
|
BRENDA:
BR19198
KEGG:
R00762;
R04780
MetaCyc:
F16BDEPHOS-RXN
SABIO-RK:
10378;
1117
|
|
|
|
trans-cinnamate <=> 3-hydroxycinnamic_acid
|
not assigned
|
–
|
|
KEGG:
R06781
|
|
|
|
3-oxo-2-(cis-2''-pentenyl)-cyclopentane-1-butanoyl-CoA + acetyl-CoA <=> 3-oxo-2-(cis-2''-pentenyl)-cyclopentane-1-(3-oxohexanoyl)-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
|
|
KEGG:
R07895
MetaCyc:
RXN-10700
|
|
|
|
L-aspartate + ATP <=> L-4-aspartyl_phosphate + ADP
|
2.7.2.4
aspartate kinase
|
–
|
|
BRENDA:
BR47827
KEGG:
R00480
MetaCyc:
ASPARTATEKIN-RXN
SABIO-RK:
912
|
|
|
|
butyryl-CoA + phosphate <=> butyryl_phosphate + CoA
|
2.3.1.19
phosphate butyryltransferase
2.3.1.222
phosphate propanoyltransferase
2.3.1.8
phosphate acetyltransferase
|
–
–
–
|
|
BRENDA:
BR44017
KEGG:
R01174
MetaCyc:
PHOSPHATE-BUTYRYLTRANSFERASE-RXN
SABIO-RK:
1411
|
|
|
|
L-ribulose_5-phosphate <=> D-xylulose_5-phosphate
|
5.1.3.4
L-ribulose-5-phosphate 4-epimerase
|
–
|
|
BRENDA:
BR198
KEGG:
R05850
MetaCyc:
RIBULPEPIM-RXN
SABIO-RK:
67
|
|
|
|
anthranilate + O2 + NADPH + H+ <=> catechol + CO2 + NH3 + NADP+
|
1.14.12.1
anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
|
–
|
|
BRENDA:
BR40446
KEGG:
R00825
MetaCyc:
1.14.12.1-RXN
|
|
|
|
UDP-glucose <=> H2O + UDP-4-dehydro-6-deoxy-D-glucose
|
4.2.1.46
dTDP-glucose 4,6-dehydratase
4.2.1.76
UDP-glucose 4,6-dehydratase
|
–
–
|
|
BRENDA:
BR453
KEGG:
R00293
MetaCyc:
UDP-GLUCOSE-46-DEHYDRATASE-RXN
|
|
|
|
myo-inositol + ATP <=> H+ + D-myo-Inositol_1-phosphate + ADP
|
2.7.1.64
inositol 3-kinase
|
–
|
|
BRENDA:
BR47388
KEGG:
R07279
MetaCyc:
MYO-INOSITOL-1-KINASE-RXN
|
|
|
|
ADP + ATP <=> ATP + ADP
|
2.4.2.12
nicotinamide phosphoribosyltransferase
2.7.1.20
adenosine kinase
2.7.4.6
nucleoside-diphosphate kinase
3.6.4.10
non-chaperonin molecular chaperone ATPase
|
–
–
–
–
|
|
BRENDA:
BS141550
KEGG:
R00124
|
|
|
|
GDP-6-deoxy-D-talose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+
|
1.1.1.135
GDP-6-deoxy-D-talose 4-dehydrogenase
1.1.1.187
GDP-4-dehydro-D-rhamnose reductase
|
–
–
|
|
BRENDA:
BR29201-a
KEGG:
R03396
MetaCyc:
GDP-6-DEOXY-D-TALOSE-4-DEHYDROGENASE-RXN_WOP
|
|
|
|
beta-L-galactose_1-phosphate + H2O <=> L-galactopyranose + phosphate
|
3.1.3.93
L-galactose 1-phosphate phosphatase
3.1.3.B9
|
–
–
|
|
BRENDA:
BR49908;
BR50987
KEGG:
R07674
MetaCyc:
RXNQT-4142
SABIO-RK:
13655
|
|
|
|
6-hydroxyprotopine <=> Dihydrosanguinarine + H2O
|
not assigned
|
–
|
|
KEGG:
R04701
MetaCyc:
RXN-8181
|
|
|
|
2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + H2O
|
2.5.1
2.5.1.15
dihydropteroate synthase
|
–
–
|
|
KEGG:
R03066
MetaCyc:
RXN-14226
|
|
|
|
D-mannitol + 2 ferricytochrome_c <=> D-fructose + 2 ferricytochrome_c + 2 H+
|
1.1.2.2
mannitol dehydrogenase (cytochrome)
|
–
|
|
BRENDA:
BR36725
KEGG:
R00865
|
|
|
|
L-lactaldehyde + NAD+ <=> methylglyoxal + NADH + H+
|
1.1.1.6
glycerol dehydrogenase
|
–
|
|
KEGG:
R10715
|
|
|
|
UDP-galactose + myo-inositol <=> H+ + 1-alpha-D-galactosyl-myo-inositol + UDP
|
2.4.1.123
inositol 3-alpha-galactosyltransferase
|
–
|
|
BRENDA:
BR47555
KEGG:
R01192;
R06214
MetaCyc:
2.4.1.123-RXN
|
|
|
|
2-Benzylmalate <=> 3-Benzylmalate
|
4.2.1
|
–
|
|
KEGG:
R10501
MetaCyc:
RXN-14463
|
|
|
|
5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2O <=> H+ + 5-formyl-5,6,7,8-tetrahydromethanopterin
|
3.5.4.27
methenyltetrahydromethanopterin cyclohydrolase
|
–
|
|
BRENDA:
BR26119
KEGG:
R03464
MetaCyc:
3.5.4.27-RXN
|
|
|
|
3beta-hydroxyergosta-7,24(241)-dien-4alpha-carboxylate + NAD+ <=> Episterone + NADH + CO2
|
1.1.1.418
plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
|
KEGG:
R12375
MetaCyc:
RXN-11933
|
|
|
|
trans-4-hydroxy-L-proline + NAD+ <=> NADH + L-1-pyrroline-3-hydroxy-5-carboxylate + H+
|
1.5.1.2
pyrroline-5-carboxylate reductase
|
–
|
|
KEGG:
R03291
MetaCyc:
RXN66-546_WOP
|
|
|
|
gibberellin_a15 + 2-oxoglutarate + O2 <=> Gibberellin_A24 + succinate + CO2 + H2O
|
1.14.11.12
gibberellin-44 dioxygenase
1.14.20
|
–
–
|
|
KEGG:
R06323
MetaCyc:
RXN1F-163
SABIO-RK:
5905
|
|
|
|
L-tyrosine + tetrahydrobiopterin + O2 <=> L-Dopa + dihydrobiopterin + H2O
|
1.14.16.2
tyrosine 3-monooxygenase
|
–
|
|
BRENDA:
BS370244
KEGG:
R01815
SABIO-RK:
1901
|
|
|
|
L-arginine + NADPH + H+ + O2 <=> L-citrulline + NO + NADP+ + H2O
|
1.14.13.39
nitric-oxide synthase (NADPH)
1.14.14.47
nitric-oxide synthase (flavodoxin)
|
–
–
|
|
BRENDA:
BR52111;
BS394886
KEGG:
R00557
MetaCyc:
NITRIC-OXIDE-SYNTHASE-RXN
SABIO-RK:
969
|
|
|
|
all-trans-retinal + H2O + O2 <=> retinoic_acid + H2O2 + H+
|
1.2.3.1
aldehyde oxidase
|
–
|
|
BRENDA:
BS258268
KEGG:
R02125
MetaCyc:
RXN-13681
|
|
|
|
N-hydroxy-L-phenylalanine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
|
BRENDA:
BR49591
KEGG:
R09580
|
|
|
|
3-Hydroxy-OPC4-CoA + NAD+ <=> 3-Oxo-OPC4-CoA + NADH + H+
|
1.1.1.211
long-chain-3-hydroxyacyl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
KEGG:
R07898
|
|
|
|
2-Amino-4-chloro-4-pentenoic_acid <=> DL-propargylglycine + Cl- + H+
|
4.5.1
|
–
|
|
KEGG:
R12409
|
|
|
|
GDP-6-deoxy-D-mannose + NAD+ <=> GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+
|
1.1.1.187
GDP-4-dehydro-D-rhamnose reductase
1.1.1.281
GDP-4-dehydro-6-deoxy-D-mannose reductase
|
–
–
|
|
BRENDA:
BR36695-a;
BS363706
KEGG:
R03397
MetaCyc:
GDP-4-DEHYDRO-D-RHAMNOSE-REDUCTASE-RXN_WOP
|
|
|
|
propionyl-CoA + enzyme_N6-(dihydrolipoyl)lysine <=> CoA + Enzyme_N6-(S-propyldihydrolipoyl)lysine
|
2.3.1.168
dihydrolipoyllysine-residue (2-methylpropanoyl)transferase
|
–
|
|
KEGG:
R10998
|
|
|
|
2-propanol + NADP+ <=> acetone + NADPH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.156
glycerol 2-dehydrogenase (NADP+)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.4
(R,R)-butanediol dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
1.1.1.80
isopropanol dehydrogenase (NADP+)
1.1.1.B4
|
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29340
KEGG:
R01550
MetaCyc:
ISOPROPANOL-DEHYDROGENASE-NADP+-RXN
SABIO-RK:
1709
|
|
|
|
p-coumaric_acid + CoA + ATP <=> 4-coumaroyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.30
phenylacetate---CoA ligase
|
–
–
–
|
|
BRENDA:
BR63
KEGG:
R01616
MetaCyc:
4-COUMARATE--COA-LIGASE-RXN
SABIO-RK:
1761
|
|
|
|
H2O + N-formimino-L-aspartate <=> NH3 + N-formyl-L-aspartate
|
3.5.3.13
formimidoylglutamate deiminase
3.5.3.5
formimidoylaspartate deiminase
|
–
–
|
|
BRENDA:
BR22729
KEGG:
R03188
MetaCyc:
FORMIMINOASPARTATE-DEIMINASE-RXN
|
|
|
|
D-xylose + NADP+ <=> D-xylono-1,4-lactone + NADPH + H+
|
1.1.1.424
D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
|
–
|
|
BRENDA:
BR53097
KEGG:
R12643
MetaCyc:
RXN-21503
|
|
|
|
tetradecanoyl-[acyl-carrier_protein] + dodecanoyl-Kdo2-lipid_IVA <=> Kdo2-lipid_A + [acyl-carrier_protein]
|
2.3.1.243
lauroyl-Kdo2-lipid IVA myristoyltransferase
|
–
|
|
BRENDA:
BS454219
KEGG:
R05075
MetaCyc:
MYRISTOYLACYLTRAN-RXN
|
|
|
|
7,9,12-Decaketide_intermediate_6 <=> 12-Deoxyaklanonic_acid
|
not assigned
|
–
|
|
KEGG:
R09326
|
|
|
|
H2O + Chlorophyll <=> chlorophyllide_a + phytol
|
3.1.1.14
chlorophyllase
|
–
|
|
BRENDA:
BR10645;
BS363953
KEGG:
R05618
MetaCyc:
CHLOROPHYLLASE-RXN;
RXN-7738
SABIO-RK:
12703;
5216
|
|
|
|
H+ + L-Dopa <=> dopamine + CO2
|
4.1.1.22
histidine decarboxylase
4.1.1.25
tyrosine decarboxylase
4.1.1.28
aromatic-L-amino-acid decarboxylase
4.1.1.53
phenylalanine decarboxylase
|
–
–
–
–
|
|
BRENDA:
BR287
KEGG:
R02080
MetaCyc:
RXN66-221
SABIO-RK:
2090
|
|
|
|
gamma-Glu-L-Cys <=> 5-oxoproline + L-cysteine
|
4.3.2.9
gamma-glutamylcyclotransferase
|
–
|
|
BRENDA:
BS321706
KEGG:
R02743
|
|
|
|
(R)-citramalate + CO2 <=> 4-hydroxy-4-methyl-2-oxoglutarate + H2O
|
not assigned
|
–
|
|
KEGG:
R03995
|
|
|
|
5-(aminomethyl)-3-furanmethanol_phosphate + ATP <=> [5-(aminomethyl)furan-3-yl]methyl_diphosphate + ADP
|
2.7.4.31
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
|
–
|
|
BRENDA:
BR51466
KEGG:
R11039
MetaCyc:
RXN-15944
|
|
|
|
D-glucose_6-phosphate + NAD+ <=> 3-dehydro-D-glucose_6-phosphate + NADH + H+
|
1.1.1.361
glucose-6-phosphate 3-dehydrogenase
|
–
|
|
BRENDA:
BR50739
KEGG:
R10519
MetaCyc:
RXN8J2-136
|
|
|
|
D-glyceraldehyde + H2O + NADP+ <=> D-glycerate + NADPH + H+
|
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.4
aldehyde dehydrogenase (NADP+)
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.8
betaine-aldehyde dehydrogenase
1.2.1.89
D-glyceraldehyde dehydrogenase (NADP+)
|
–
–
–
–
–
–
|
|
BRENDA:
BR50850;
BS287728
KEGG:
R10615
MetaCyc:
RXN-15115
SABIO-RK:
7330
|
|
|
|
L-proline + 2-oxoglutarate + O2 <=> trans-4-hydroxy-L-proline + succinate + CO2
|
1.14.11.2
procollagen-proline 4-dioxygenase
1.14.11.57
L-proline trans-4-hydroxylase
|
–
–
|
|
BRENDA:
BR51935;
BS288710
KEGG:
R01252
MetaCyc:
RXN490-3641
|
|
|
|
acyl-CoA + sphingosine <=> ceramide + CoA + H+
|
2.3.1.24
sphingosine N-acyltransferase
2.3.1.291
sphingoid base N-palmitoyltransferase
|
–
–
|
|
BRENDA:
BR44023
KEGG:
R01496
MetaCyc:
RXN-20352;
SPHINGOSINE-N-ACYLTRANSFERASE-RXN
|
|
|
|
S-adenosyl-L-methionine + uroporphyrinogen_III <=> S-adenosyl-L-homocysteine + precorrin-2 + H+
|
2.1.1.107
uroporphyrinogen-III C-methyltransferase
|
–
|
|
BRENDA:
BR51020
KEGG:
R03194
MetaCyc:
RXN-13403
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> longifolene + diphosphate
|
4.2.3.58
longifolene synthase
|
–
|
|
BRENDA:
BR49429
KEGG:
R08542
MetaCyc:
RXN-8540
|
|
|
|
phosphatidylinositol_4,5-bisphosphate + H2O <=> diacylglycerol + 1D-myo-inositol_1,4,5-trisphosphate + H+
|
3.1.4.11
phosphoinositide phospholipase C
3.1.4.3
phospholipase C
|
–
–
|
|
BRENDA:
BR48403
KEGG:
R03435
MetaCyc:
3.1.4.11-RXN
SABIO-RK:
3231
|
|
|
|
5-aminoimidazole-4-carboxamide_ribonucleotide + formate + ATP <=> 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide + ADP + phosphate
|
6.3.4.23
formate---phosphoribosylaminoimidazolecarboxamide ligase
|
–
|
|
BRENDA:
BR50732
KEGG:
R06975
MetaCyc:
RXN-10066
|
|
|
|
2-((1R,3S),-1,9''-dihydroxy-1''-methyl-10''-oxo-3,4,5,10''-tetrahydro-1H-benzo[g]isochromen-3''-yl)acetate <=> (S)-DNPA + H2O
|
4.2.1
|
–
|
|
KEGG:
R09308
MetaCyc:
RXN1A0-6314
|
|
|
|
4-hydroxy-4-methyl-2-oxoglutarate <=> pyruvate
|
4.1.3.17
4-hydroxy-4-methyl-2-oxoglutarate aldolase
|
–
|
|
BRENDA:
BR3367
KEGG:
R00008
MetaCyc:
4.1.3.17-RXN
SABIO-RK:
6474
|
|
|
|
2-hydroxy-2H-chromene-2-carboxylate <=> (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate
|
2.5.1.18
glutathione transferase
5.99.1.4
2-hydroxychromene-2-carboxylate isomerase
|
–
–
|
|
BRENDA:
BR49209
KEGG:
R05137
MetaCyc:
RXNN-386
|
|
|
|
amylose <=> alpha-cyclodextrin
|
2.4.1.19
cyclomaltodextrin glucanotransferase
3.2.1.54
cyclomaltodextrinase
|
–
–
|
|
BRENDA:
BR16009;
BS372798;
BS377790;
BS389790;
BS408388
KEGG:
R03122;
R06160;
R11260
MetaCyc:
2.4.1.19-RXN;
CYCLOMALTODEXTRINASE-RXN;
RXN-12181
SABIO-RK:
13624
|
|
|
|
2,4,5-Trichlorophenol + O2 + FADH2 <=> 2,5-dichlorohydroquinone + Cl- + H2O + FAD + H+
|
1.14.14
|
–
|
|
KEGG:
R05447
MetaCyc:
RXN-10134
|
|
|
|
amidinoproclavaminate + H2O <=> proclavaminate + Urea
|
3.5.3.22
proclavaminate amidinohydrolase
|
–
|
|
BRENDA:
BR47584
KEGG:
R05357
MetaCyc:
3.5.3.22-RXN
|
|
|
|
1-hydroxylycopene <=> lycopene + H2O
|
4.2.1.131
carotenoid 1,2-hydratase
|
–
|
|
BRENDA:
BR49811
KEGG:
R07519
MetaCyc:
RXN-10643
|
|
|
|
3-Hydroxy-OPC6-CoA <=> trans-2-Enoyl-OPC6-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
4.2.1.74
long-chain-enoyl-CoA hydratase
|
–
–
|
|
KEGG:
R07893
|
|
|
|
amylose <=> glycogen
|
2.4.1.18
1,4-alpha-glucan branching enzyme
2.4.1.25
4-alpha-glucanotransferase
3.2.1.1
alpha-amylase
3.2.1.116
glucan 1,4-alpha-maltotriohydrolase
3.2.1.133
glucan 1,4-alpha-maltohydrolase
3.2.1.135
neopullulanase
3.2.1.41
pullulanase
3.2.1.54
cyclomaltodextrinase
3.2.1.68
isoamylase
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS322548;
BS361119;
BS371171;
BS373329;
BS380763
KEGG:
R02110;
R06186;
R06209;
R11261
MetaCyc:
GLYCOGEN-BRANCH-RXN;
RXN-4301;
RXN-7710
|
|
|
|
CMP-N-acetylneuraminate + GD1a <=> CMP + GT1a
|
2.4.99
|
–
|
|
KEGG:
R05943
|
|
|
|
4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD+ <=> avenastenone + NADH + CO2
|
1.1.1.418
plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
|
KEGG:
R12376
MetaCyc:
RXN-11938
|
|
|
|
(+)-7-Isojasmonate_CoA + acetyl-CoA <=> 3-oxo-2-(cis-2''-pentenyl)-cyclopentane-1-(3-oxobutanoyl)-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
|
|
KEGG:
R07899
MetaCyc:
RXN-10701
|
|
|
|
phenylacetyl-CoA + H2O <=> phenylacetate + CoA + H+
|
3.1.2
3.1.2.20
acyl-CoA hydrolase
3.1.2.23
4-hydroxybenzoyl-CoA thioesterase
3.1.2.25
phenylacetyl-CoA hydrolase
3.1.2.B5
|
–
–
–
–
–
|
|
BRENDA:
BS364466
KEGG:
R09840
MetaCyc:
RXN0-7104
SABIO-RK:
12738
|
|
|
|
dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose + acetyl-CoA <=> dTDP-3-acetamido-3,6-dideoxy-alpha-D-glucose + CoA + H+
|
2.3.1
|
–
|
|
KEGG:
R12549
MetaCyc:
RXN-14735
|
|
|
|
2-oxosuccinamic_acid + H2O <=> oxaloacetate + NH3
|
3.5.1.3
omega-amidase
|
–
|
|
BRENDA:
BS189843
KEGG:
R00348
MetaCyc:
RXN-6562
SABIO-RK:
822
|
|
|
|
5,10-methylenetetrahydrofolate + 2-oxoisovalerate + H2O <=> ketopantoate + tetrahydrofolate
|
2.1.2.11
3-methyl-2-oxobutanoate hydroxymethyltransferase
|
–
|
|
BRENDA:
BR43940
KEGG:
R01226
MetaCyc:
3-CH3-2-OXOBUTANOATE-OH-CH3-XFER-RXN
SABIO-RK:
1455
|
|
|
|
aurachin_B + NAD+ + H2O <=> 4-hydroxy-2-methyl-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]quinolin-3(4H)-one_1-oxide + NADH + H+
|
1.1.1.394
aurachin B dehydrogenase
|
–
|
|
BRENDA:
BR51560
KEGG:
R11149
MetaCyc:
RXN-17420
|
|
|
|
cyanuric_acid + H2O <=> carboxybiuret + H+
|
3.5.2.15
cyanuric acid amidohydrolase
|
–
|
|
BRENDA:
BR26105
KEGG:
R12332
MetaCyc:
RXN-20062
|
|
|
|
phosphatidylethanolamine + H2O <=> ethanolamine + phosphatidic_acid
|
3.1.4.4
phospholipase D
|
–
|
|
BRENDA:
BS364671
KEGG:
R02051
|
|
|
|
dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin_alpha1(I) <=> dTDP + Calicheamicin_gamma(1)I
|
2.4.1
|
–
|
|
KEGG:
R11422
|
|
|
|
ent-copalyl_diphosphate <=> diphosphate + ent-kaurene
|
4.2.3.19
ent-kaurene synthase
5.5.1.13
ent-copalyl diphosphate synthase
|
–
–
|
|
BRENDA:
BR44342;
BS323512;
BS444312
KEGG:
R05092
MetaCyc:
4.2.3.19-RXN
|
|
|
|
UDP-N-acetyl-D-glucosamine + trans,octacis-decaprenyl_phosphate <=> N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol + UMP
|
2.7.8.35
UDP-N-acetylglucosamine---decaprenyl-phosphate N-acetylglucosaminephosphotransferase
|
–
|
|
BRENDA:
BR50195
KEGG:
R10137;
R12075
MetaCyc:
RXN-6380
|
|
|
|
dGTP + thioredoxin_disulfide + H2O <=> GTP + thioredoxin
|
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
|
|
BRENDA:
BS287788
KEGG:
R02020
MetaCyc:
RXN-21263
SABIO-RK:
2052
|
|
|
|
S-adenosyl-L-methionine + carnosine <=> H+ + S-adenosyl-L-homocysteine + anserine
|
2.1.1.22
carnosine N-methyltransferase
|
–
|
|
BRENDA:
BR43889
KEGG:
R02144
MetaCyc:
CARNOSINE-N-METHYLTRANSFERASE-RXN
SABIO-RK:
2129
|
|
|
|
D-Lysine + H+ <=> cadaverine + CO2
|
4.1.1.116
D-ornithine/D-lysine decarboxylase
6707
|
–
–
|
|
BRENDA:
BR52450
KEGG:
R12305
MetaCyc:
RXN-20176
|
|
|
|
L-N-acetyl-2-amino-6-oxopimelate + L-glutamate <=> N-acetyl-L,L-2,6-diaminopimelate + 2-oxoglutarate
|
2.6.1
|
–
|
|
KEGG:
R04467
MetaCyc:
RXN-4822
|
|
|
|
taurine + 2-oxoglutarate <=> L-glutamate + 2-sulfoacetaldehyde
|
2.6.1.55
taurine---2-oxoglutarate transaminase
|
–
|
|
BRENDA:
BR47391
KEGG:
R01684
MetaCyc:
RXN-2301
|
|
|
|
S-adenosyl-L-methionine + Demethylmacrocin <=> H+ + S-adenosyl-L-homocysteine + macrocin
|
2.1.1.102
demethylmacrocin O-methyltransferase
|
–
|
|
BRENDA:
BR43861
KEGG:
R02859
MetaCyc:
DEMETHYLMACROCIN-O-METHYLTRANSFERASE-RXN
|
|
|
|
(3S)-3-hydroxytetradecanoyl-CoA <=> 2-tetradecenoyl-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
4.2.1.74
long-chain-enoyl-CoA hydratase
|
–
–
|
|
BRENDA:
BS2105
KEGG:
R04740
MetaCyc:
RXN-14273
SABIO-RK:
4396
|
|
|
|
L-lysine + acetyl-CoA <=> H+ + N6-acetyl-L-lysine + CoA
|
2.3.1
2.3.1.32
lysine N-acetyltransferase
|
–
–
|
|
BRENDA:
BS407086
KEGG:
R00454
MetaCyc:
LYSACET-RXN
|
|
|
|
5-hydroxy-L-tryptophan + O2 <=> 5-hydroxy-N-formylkynurenine
|
1.13.11.26
peptide-tryptophan 2,3-dioxygenase
1.13.11.52
indoleamine 2,3-dioxygenase
|
–
–
|
|
BRENDA:
BS288941;
BS381253;
BS440925
KEGG:
R02702
SABIO-RK:
2595
|
|
|
|
(2E,4Z)-2-hydroxyhexa-2,4-dienoate + H2O <=> 4-hydroxy-2-oxohexanoate
|
4.2.1.132
2-hydroxyhexa-2,4-dienoate hydratase
|
–
|
|
KEGG:
R05864
|
|
|
|
CMP-N-acetylneuraminate + ganglioside_GD3 <=> CMP + GT3
|
2.4.99.8
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase
|
–
|
|
KEGG:
R05947
|
|
|
|
2-dehydro-3-deoxy-D-galactonate + ATP <=> H+ + 2-dehydro-3-deoxy-D-galactonate_6-phosphate + ADP
|
2.7.1.178
2-dehydro-3-deoxyglucono/galactono-kinase
2.7.1.58
2-dehydro-3-deoxygalactonokinase
|
–
–
|
|
BRENDA:
BR47788
KEGG:
R03387
MetaCyc:
DEHYDDEOXGALACTKIN-RXN
|
|
|
|
Caffeine + NADPH + O2 + H+ <=> Theobromine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
|
BRENDA:
BR50577
KEGG:
R07956
MetaCyc:
RXN-11513
|
|
|
|
Nonaketamide_tricyclic_intermediate <=> Pretetramid
|
not assigned
|
–
|
|
KEGG:
R09196
|
|
|
|
geranyl_diphosphate <=> (-)-camphene + diphosphate
|
4.2.3
4.2.3.116
(+)-camphene synthase
4.2.3.117
(-)-camphene synthase
|
–
–
–
|
|
BRENDA:
BR50080
KEGG:
R02011;
R09972
MetaCyc:
RXN-5142
|
|
|
|
geranyl_diphosphate + H2O <=> (-)-alpha-terpineol + diphosphate
|
4.2.3.108
1,8-cineole synthase
4.2.3.111
(-)-alpha-terpineol synthase
4.2.3.112
(+)-alpha-terpineol synthase
|
–
–
–
|
|
BRENDA:
BR50074;
BS444324
KEGG:
R06421
MetaCyc:
RXN-5101
|
|
|
|
dADP + thioredoxin_disulfide + H2O <=> ADP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
|
BRENDA:
BS287791
KEGG:
R02017
MetaCyc:
ADPREDUCT-RXN
|
|
|
|
decanoyl-CoA + acetyl-CoA <=> 3-oxododecanoyl-CoA + CoA
|
2.3.1.155
acetyl-CoA C-myristoyltransferase
2.3.1.16
acetyl-CoA C-acyltransferase
|
–
–
|
|
BRENDA:
BS189547
KEGG:
R04742
MetaCyc:
RXN-14274
SABIO-RK:
4398
|
|
|
|
D-glycero-beta-D-manno-heptose_1,7-bisphosphate + H2O <=> D-glycero-beta-D-manno-heptose_1-phosphate + phosphate
|
3.1.3.82
D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase
|
–
|
|
BRENDA:
BR49195
KEGG:
R05647
MetaCyc:
RXN0-4361
|
|
|
|
heme_O <=> heme_a
|
not assigned
|
–
|
|
KEGG:
R07412
|
|
|
|
1-hydroxyneurosporene <=> all-trans-neurosporene + H2O
|
4.2.1.131
carotenoid 1,2-hydratase
|
–
|
|
BRENDA:
BS417405
KEGG:
R07532
MetaCyc:
RXN-10665
|
|
|
|
NTP + pyruvate <=> NDP + phosphoenolpyruvate
|
2.7.1.40
pyruvate kinase
|
–
|
|
KEGG:
R02320
|
|
|
|
ITP + cytidine <=> IDP + CMP
|
2.7.1.48
uridine/cytidine kinase
2.7.1.B20
|
–
–
|
|
BRENDA:
BS428712
KEGG:
R00962
|
|
|
|
2-Fluorobenzoate + NADH + H+ + O2 <=> 2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
|
1.14.12.10
benzoate 1,2-dioxygenase
|
–
|
|
KEGG:
R08100
|
|
|
|
arachidonic_acid + O2 <=> prostaglandin_G2
|
1.14.99.1
prostaglandin-endoperoxide synthase
|
–
|
|
BRENDA:
BS387885
KEGG:
R01590
MetaCyc:
RXN-16678
SABIO-RK:
1740
|
|
|
|
spheroidene + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> spheroiden-2-one + H2O + oxidized_ferredoxin
|
1.14.15.9
spheroidene monooxygenase
|
–
|
|
BRENDA:
BR49655;
BS413612
KEGG:
R07537
MetaCyc:
RXN-10670
|
|
|
|
S-adenosyl-L-methionine + Xanthosine <=> 7-methylxanthosine + S-adenosyl-L-homocysteine
|
2.1.1.158
7-methylxanthosine synthase
|
–
|
|
BRENDA:
BR48812
KEGG:
R07917
MetaCyc:
RXN-7596
SABIO-RK:
15254
|
|
|
|
ATP + D-ribulose <=> H+ + ADP + D-ribulose_5-phosphate
|
2.7.1.16
ribulokinase
2.7.1.47
D-ribulokinase
|
–
–
|
|
BRENDA:
BR47781
KEGG:
R01526
MetaCyc:
D-RIBULOKIN-RXN
|
|
|
|
D-glucose + NAD+ <=> D-glucono-1,5-lactone + NADH + H+
|
1.1.1.118
glucose 1-dehydrogenase (NAD+)
1.1.1.119
glucose 1-dehydrogenase (NADP+)
1.1.1.121
aldose 1-dehydrogenase (NAD+)
1.1.1.179
D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.47
glucose 1-dehydrogenase [NAD(P)+]
|
–
–
–
–
–
|
|
BRENDA:
BR29183;
BS355809
KEGG:
R00300;
R01520
MetaCyc:
GLUCOSE-1-DEHYDROGENASE-NAD+-RXN;
GLUCOSE-1-DEHYDROGENASE-RXN_WOP
SABIO-RK:
1689;
19
|
|
|
|
divinyl_protochlorophyllide_a + 2 H+ <=> protochlorophyllide
|
not assigned
|
–
|
|
KEGG:
R06271
|
|
|
|
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde <=> quinolinic_acid + H2O + H+
|
not assigned
|
–
|
|
KEGG:
R04293
MetaCyc:
RXN-5721
|
|
|
|
dTDP-3-dehydro-2,6-dideoxy-alpha-D-glucose <=> TDP-3-amino-2,3,6-trideoxy-alpha-D-glucose
|
not assigned
|
–
|
|
KEGG:
R08928
|
|
|
|
D-lactate + H+ <=> methylglyoxal + H2O
|
3.5.1.124
protein deglycase
4.2.1.130
D-lactate dehydratase
|
–
–
|
|
BRENDA:
BR49777
KEGG:
R09796
MetaCyc:
GLYOXIII-RXN
|
|
|
|
S-adenosyl-L-methionine + 3,4-Dihydroxyphenylacetate <=> H+ + homovanillic_acid + S-adenosyl-L-homocysteine
|
2.1.1.6
catechol O-methyltransferase
|
–
|
|
KEGG:
R03304
MetaCyc:
RXN6666-6
|
|
|
|
(R)-2-hydroxyglutarate + pyruvate <=> 2-oxoglutarate + D-lactate
|
1.1.99.40
(R)-2-hydroxyglutarate---pyruvate transhydrogenase
|
–
|
|
BRENDA:
BR51923
KEGG:
R11593
MetaCyc:
RXN-18432
|
|
|
|
NH3 + H2O + oxidized_ferredoxin <=> nitrite + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.7.7.1
ferredoxin---nitrite reductase
1.8.7.1
assimilatory sulfite reductase (ferredoxin)
|
–
–
|
|
BRENDA:
BR36987
KEGG:
R00790
MetaCyc:
FERREDOXIN--NITRITE-REDUCTASE-RXN
SABIO-RK:
1137
|
|
|
|
ent-7alpha-hydroxykaur-16-en-19-oate + reduced_flavodoxin + O2 <=> gibberellin_A12_aldehyde + flavin + 2 H2O
|
1.14.14.107
ent-kaurenoic acid monooxygenase
|
–
|
|
BRENDA:
BR40544
KEGG:
R06295
|
|
|
|
D-mannose <=> D-fructose
|
5.3.1.15
D-lyxose ketol-isomerase
5.3.1.5
xylose isomerase
5.3.1.7
mannose isomerase
5.3.1.B3
|
–
–
–
–
|
|
BRENDA:
BR238
KEGG:
R00877
SABIO-RK:
585
|
|
|
|
UDP-N,N''-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+
|
3.2.1.184
UDP-N,N'-diacetylbacillosamine 2-epimerase (hydrolysing)
|
–
|
|
BRENDA:
BR50320
KEGG:
R10187
MetaCyc:
RXN-13574
|
|
|
|
D-chiro-Inositol + NAD+ <=> 2D-2,3,5/4,6-pentahydroxycyclohexanone + NADH + H+
|
1.1.1.18
inositol 2-dehydrogenase
1.1.1.369
D-chiro-inositol 1-dehydrogenase
|
–
–
|
|
BRENDA:
BR50930
KEGG:
R09951
MetaCyc:
RXN-14148
|
|
|
|
TDP-3-amino-2,3,6-trideoxy-alpha-D-glucose <=> dTDP-D-angolosamine
|
not assigned
|
–
|
|
KEGG:
R08929
|
|
|
|
H+ + L-phenylalanine <=> 2-Phenylethylamine + CO2
|
4.1.1.14
valine decarboxylase
4.1.1.19
arginine decarboxylase
4.1.1.25
tyrosine decarboxylase
4.1.1.28
aromatic-L-amino-acid decarboxylase
4.1.1.53
phenylalanine decarboxylase
|
–
–
–
–
–
|
|
BRENDA:
BR313
KEGG:
R00699
MetaCyc:
PHENYLALANINE-DECARBOXYLASE-RXN
|
|
|
|
trypanothione + H2O <=> glutathione + glutathionylspermidine
|
3.5.1
3.5.1.78
glutathionylspermidine amidase
|
–
–
|
|
BRENDA:
BS367840
KEGG:
R08350
|
|
|
|
succinate + GTP + CoA <=> succinyl-CoA + GDP + phosphate
|
6.2.1.4
succinate---CoA ligase (GDP-forming)
|
–
|
|
BRENDA:
BR87
KEGG:
R00432
MetaCyc:
SUCCINATE--COA-LIGASE-GDP-FORMING-RXN
SABIO-RK:
259
|
|
|
|
UDP-N-acetyl-D-galactosamine + beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-1-Ser <=> UDP + beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-1-Ser
|
2.4.1.175
glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase
|
–
|
|
KEGG:
R05932
|
|
|
|
L-ribulose + ATP <=> H+ + L-ribulose_5-phosphate + ADP
|
2.7.1.16
ribulokinase
2.7.1.17
xylulokinase
|
–
–
|
|
BRENDA:
BS357306
KEGG:
R02439
MetaCyc:
RXN0-5116
|
|
|
|
(3R)-3-hydroxybutanoyl-[acyl-carrier_protein] + NADP+ <=> acetoacetyl-[acyl-carrier_protein] + NADPH + H+
|
1.1.1
1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
–
–
–
|
|
BRENDA:
BS186945
KEGG:
R04533
MetaCyc:
RXN-9514
|
|
|
|
2-oxobutyrate + thiamine_diphosphate <=> 2-(alpha-Hydroxypropyl)thiamine_diphosphate + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
KEGG:
R10996
|
|
|
|
2-deoxy-D-ribose_5-phosphate <=> D-glyceraldehyde_3-phosphate + acetaldehyde
|
4.1.2.4
deoxyribose-phosphate aldolase
|
–
|
|
BRENDA:
BR371
KEGG:
R01066
MetaCyc:
DEOXYRIBOSE-P-ALD-RXN
SABIO-RK:
64
|
|
|
|
avenasterol + ferricytochrome_b5 + O2 + H+ <=> DELTA5,7-avenasterol + ferricytochrome_b5 + H2O
|
1.14.19.20
Delta7-sterol 5(6)-desaturase
|
–
|
|
KEGG:
R07486
MetaCyc:
RXN-4209
|
|
|
|
acetoacetate <=> 3-Butynoate + H2O
|
4.2.1.27
acetylenecarboxylate hydratase
|
–
|
|
KEGG:
R01367
|
|
|
|
H+ + (2S)-2-isopropyl-3-oxosuccinate <=> 4-methyl-2-oxopentanoate + CO2
|
0.0.0.0
1.1.1.85
3-isopropylmalate dehydrogenase
|
–
–
|
|
BRENDA:
BR52894
KEGG:
R01652
MetaCyc:
RXN-7800
|
|
|
|
(S)-3-hydroxydecanoyl-CoA + NAD+ <=> 3-oxodecanoyl-CoA + NADH + H+
|
1.1.1.211
long-chain-3-hydroxyacyl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
BRENDA:
BS188068
KEGG:
R04743
MetaCyc:
RXN-12490
SABIO-RK:
4399
|
|
|
|
(2S)-2-phospholactate + GTP + H+ <=> L-lactyl-2-diphospho-5''-guanosine + diphosphate
|
2.7.7.68
2-phospho-L-lactate guanylyltransferase
|
–
|
|
BRENDA:
BR49188
KEGG:
R09397
MetaCyc:
RXN-21088
SABIO-RK:
13214
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + O2 <=> (S)-4-hydroxymandelonitrile + flavin + 2 H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
|
BRENDA:
BR29144
KEGG:
R05728
|
|
|
|
(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate <=> o-succinylbenzoate + H2O
|
4.2.1.113
o-succinylbenzoate synthase
|
–
|
|
BRENDA:
BR48469;
BS368326
KEGG:
R04031
MetaCyc:
O-SUCCINYLBENZOATE-COA-SYN-RXN
SABIO-RK:
3766
|
|
|
|
5,6-dihydrouracil + NAD+ <=> Uracil + NADH + H+
|
1.3.1.1
dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2
dihydropyrimidine dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BR33754
KEGG:
R00977
MetaCyc:
DIHYDROURACIL-DEHYDROGENASE-NAD+-RXN
SABIO-RK:
470
|
|
|
|
nocardicin_G <=> nocardicin_E
|
not assigned
|
–
|
|
KEGG:
R10903
|
|
|
|
ATP + acetate <=> diphosphate + acetyl_adenylate
|
6.2.1.1
acetate---CoA ligase
|
–
|
|
KEGG:
R00316
|
|
|
|
fecosterol <=> episterol
|
not assigned
|
–
|
|
KEGG:
R07497
MetaCyc:
RXN3O-203
|
|
|
|
N-acetyl-D-mannosamine_6-phosphate + phosphoenolpyruvate + H2O <=> N-acetylneuraminate_9-phosphate + phosphate
|
2.5.1.56
N-acetylneuraminate synthase
2.5.1.57
N-acylneuraminate-9-phosphate synthase
|
–
–
|
|
BRENDA:
BS354664
KEGG:
R04435
SABIO-RK:
4121
|
|
|
|
R-S-glutathione + H2O <=> an_(L-cysteinylglycine)-S-conjugate + L-glutamate
|
2.3.2.2
gamma-glutamyltransferase
3.4.19.13
glutathione gamma-glutamate hydrolase
|
–
–
|
|
BRENDA:
BR52698
KEGG:
R03916
MetaCyc:
RXN-6641
|
|
|
|
4,5-9,10-diseco-3-hydroxy-5,9,17-tri-oxoandrosta-1(10),2-diene-4-oic_acid + H2O <=> 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+
|
3.7.1.17
4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase
|
–
|
|
BRENDA:
BR49990
KEGG:
R09883
MetaCyc:
RXN-12718
|
|
|
|
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose <=> dTDP-3-dehydro-2,6-dideoxy-alpha-D-glucose
|
not assigned
|
–
|
|
KEGG:
R08927
|
|
|
|
L-1-pyrroline-3-hydroxy-5-carboxylate + NAD+ + H2O <=> H+ + L-erythro-4-hydroxyglutamate + NADH
|
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
1.5.1
|
–
–
|
|
KEGG:
R04444
MetaCyc:
HYDROXYPYRROLINEDEH-RXN
|
|
|
|
alpha-D-mannose_1-phosphate <=> D-mannose_6-phosphate
|
5.4.2.10
phosphoglucosamine mutase
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.8
phosphomannomutase
|
–
–
–
|
|
BRENDA:
BR24;
BS1189
KEGG:
R01818
MetaCyc:
PHOSMANMUT-RXN
SABIO-RK:
69
|
|
|
|
4-(hydroxymethyl)-2-furancarboxaldehyde_phosphate + L-alanine <=> 5-(aminomethyl)-3-furanmethanol_phosphate + pyruvate
|
2.6.1.108
(5-formylfuran-3-yl)methyl phosphate transaminase
|
–
|
|
BRENDA:
BR51409
KEGG:
R11038
MetaCyc:
RXN-8119
|
|
|
|
Avermectin_B1b_aglycone + dTDP-L-oleandrose <=> Avermectin_B1b_monosaccharide + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06496
|
|
|
|
hydrogenobyrinic_acid_a,c-diamide + Co2+ + ATP + H2O <=> H+ + cob(II)yrinic_acid_a,c-diamide + ADP + phosphate
|
6.6.1.2
cobaltochelatase
|
–
|
|
BRENDA:
BR48015
KEGG:
R05227
MetaCyc:
R342-RXN
|
|
|
|
acyl-CoA + sphinganine <=> dihydroceramide + CoA + H+
|
2.3.1.24
sphingosine N-acyltransferase
2.3.1.291
sphingoid base N-palmitoyltransferase
2.3.1.297
very-long-chain ceramide synthase
|
–
–
–
|
|
BRENDA:
BS320738;
BS449519
KEGG:
R06517
MetaCyc:
RXN-7792
|
|
|
|
demethylphylloquinone + NADPH + H+ <=> demethylphylloquinol + NADP+
|
1.6.5.12
demethylphylloquinone reductase
|
–
|
|
BRENDA:
BR51489
KEGG:
R11061
MetaCyc:
RXN-17007
|
|
|
|
(R)-(indol-3-yl)lactate + NAD+ <=> 3-Indole-2-oxopropanoate + NADH + H+
|
1.1.1.110
aromatic 2-oxoacid reductase
|
–
|
|
BRENDA:
BR29176
KEGG:
R12256
MetaCyc:
INDOLELACTATE-DEHYDROGENASE-RXN
|
|
|
|
(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate <=> succinate + pyruvate
|
4.1.3.1
isocitrate lyase
4.1.3.30
methylisocitrate lyase
|
–
–
|
|
BRENDA:
BR390;
BS417300
KEGG:
R00409
MetaCyc:
METHYLISOCITRATE-LYASE-RXN
SABIO-RK:
866
|
|
|
|
S-adenosyl-L-methionine + tryptamine <=> S-adenosyl-L-homocysteine + N-methyltryptamine + H+
|
2.1.1.49
amine N-methyltransferase
|
–
|
|
BRENDA:
BS289589
KEGG:
R02174
MetaCyc:
RXN-19909
SABIO-RK:
2148
|
|
|
|
4-(phosphonooxy)-L-threonine + NAD+ <=> 2-amino-3-oxo-4-phosphonooxybutyrate + NADH
|
1.1.1.262
4-hydroxythreonine-4-phosphate dehydrogenase
|
–
|
|
BRENDA:
BS139544
KEGG:
R05681
|
|
|
|
Butyraldehyde + CoA + NADP+ <=> butyryl-CoA + NADPH + H+
|
1.2.1.10
acetaldehyde dehydrogenase (acetylating)
1.2.1.57
butanal dehydrogenase
1.2.1.76
succinate-semialdehyde dehydrogenase (acylating)
|
–
–
–
|
|
BRENDA:
BR1123
KEGG:
R01173
MetaCyc:
BUTANAL-DEHYDROGENASE-RXN
SABIO-RK:
1410
|
|
|
|
UDP-N-acetyl-D-glucosamine + nLc6Cer <=> UDP + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer
|
2.4.1.150
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase
|
–
|
|
KEGG:
R06189
|
|
|
|
ATP + 4-methoxy-2,2''-bipyrrole-5-carbaldehyde + 2-Methyl-3-n-amyl-pyrrole <=> ADP + phosphate + prodigiosin + H+
|
6.4.1
|
–
|
|
KEGG:
R11662
MetaCyc:
RXN-15787
|
|
|
|
sulfate + H+ + ADP <=> adenosine_5''-phosphosulfate + phosphate
|
2.7.7.5
sulfate adenylyltransferase (ADP)
|
–
|
|
BRENDA:
BR47891
KEGG:
R00530
MetaCyc:
SULFATE-ADENYLYLTRANSFERASE-ADP-RXN
|
|
|
|
palmitoyl-CoA + H2O <=> H+ + palmitate + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
3.1.1.1
carboxylesterase
3.1.1.23
acylglycerol lipase
3.1.1.5
lysophospholipase
3.1.2
3.1.2.1
acetyl-CoA hydrolase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.22
palmitoyl[protein] hydrolase
3.1.2.25
phenylacetyl-CoA hydrolase
|
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR48147;
BS115468
KEGG:
R01274;
R08174;
R09450
MetaCyc:
PALMITOYL-COA-HYDROLASE-RXN;
RXN-16395;
RXN-9624
SABIO-RK:
1490;
6573
|
|
|
|
H+ + S-methyl-5''-thioadenosine + H2O <=> S-methyl-5''-thioinosine + NH3
|
3.5.4.31
S-methyl-5'-thioadenosine deaminase
3.5.4.4
adenosine deaminase
|
–
–
|
|
BRENDA:
BR49648
KEGG:
R09660
MetaCyc:
RXN-10035
SABIO-RK:
14985
|
|
|
|
D-galactose + O2 + H2O <=> D-galactonate + H2O2
|
1.1.3.9
galactose oxidase
|
–
|
|
KEGG:
R01098
|
|
|
|
UDP-N-acetyl-D-glucosamine + H2O <=> N-acetyl-D-mannosamine + UDP
|
3.2.1.183
UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
5.1.3.14
UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing)
|
–
–
|
|
BRENDA:
BR50319
KEGG:
R00414
SABIO-RK:
869
|
|
|
|
Toluene + O2 + NADH + H+ <=> p-Cresol + H2O + NAD+
|
1.14.13.236
toluene 4-monooxygenase
|
–
|
|
BRENDA:
BR52031
KEGG:
R05666
MetaCyc:
TOLUENE-4-MONOOXYGENASE-RXN
|
|
|
|
tyramine + O2 + H2O <=> 4-hydroxyphenylacetaldehyde + NH3 + H2O2
|
1.4.3.10
putrescine oxidase
1.4.3.21
primary-amine oxidase
1.4.3.22
diamine oxidase
1.4.3.4
monoamine oxidase
1.4.9.2
aralkylamine dehydrogenase (azurin)
|
–
–
–
–
–
|
|
BRENDA:
BS259130
KEGG:
R02382
MetaCyc:
RXN-5821
SABIO-RK:
2326
|
|
|
|
adenosine + H2O + H+ <=> Inosine + NH3
|
3.5.4.4
adenosine deaminase
|
–
|
|
BRENDA:
BR22741
KEGG:
R01560
MetaCyc:
ADENODEAMIN-RXN
SABIO-RK:
134
|
|
|
|
methanethiol + coenzyme_M <=> methyl-CoM + Sulfide + H+
|
2.1.1.251
methylated-thiol---coenzyme M methyltransferase
|
–
|
|
BRENDA:
BR50045
KEGG:
R09997
MetaCyc:
RXN-13229
|
|
|
|
NADP+ + CoA + (R)-mevalonate <=> H+ + NADPH + (S)-3-hydroxy-3-methylglutaryl-CoA
|
1.1.1.34
hydroxymethylglutaryl-CoA reductase (NADPH)
1.1.1.88
hydroxymethylglutaryl-CoA reductase
1.1.1.B38
|
–
–
–
|
|
BRENDA:
BR29297;
BR50597;
BS188050;
BS451044
KEGG:
R02082
MetaCyc:
1.1.1.34-RXN
SABIO-RK:
2092
|
|
|
|
(S)-2-Hydroxy-2-methyl-3-oxobutanoate <=> 3-hydroxy-3-methyl-2-oxobutanoic_acid
|
1.1.1.86
ketol-acid reductoisomerase (NADP+)
5.4.99.3
2-acetolactate mutase
|
–
–
|
|
BRENDA:
BR250
KEGG:
R03052;
R05071
MetaCyc:
2-ACETOLACTATE-MUTASE-RXN
SABIO-RK:
2898
|
|
|
|
DELTA1-piperideine + acetoacetyl-CoA + H2O <=> Pelletierine + CoA + CO2
|
not assigned
|
–
|
|
KEGG:
R05129
|
|
|
|
S-adenosyl-L-methionine + 1-hydroxyneurosporene <=> 1-methoxyneurosporene + S-adenosyl-L-homocysteine + H+
|
2.1.1
2.1.1.210
demethylspheroidene O-methyltransferase
|
–
–
|
|
KEGG:
R07533
MetaCyc:
RXN-10668
|
|
|
|
Caffeine + O2 + NADPH + H+ <=> theophylline + formaldehyde + NADP+ + H2O
|
1.13.12
1.14.13.128
7-methylxanthine demethylase
|
–
–
|
|
BRENDA:
BS417831
KEGG:
R07972
|
|
|
|
(S)-3-hydroxybutyryl-CoA <=> (3R)-hydroxybutyryl-CoA
|
5.1.2.3
3-hydroxybutyryl-CoA epimerase
|
–
|
|
BRENDA:
BR180
KEGG:
R03276
MetaCyc:
5.1.2.3-RXN
|
|
|
|
thiosulfate + 5 H2O + 8 ferricytochrome_c <=> 2 sulfate + 8 ferricytochrome_c + 10 H+
|
not assigned
|
–
|
|
KEGG:
R10151
|
|
|
|
L-cysteine + NAD+ <=> H+ + L-cystine + NADH
|
1.8.1.6
cystine reductase
|
–
|
|
BRENDA:
BR40533
KEGG:
R00892
MetaCyc:
CYSTINE-REDUCTASE-NADH-RXN
|
|
|
|
L-xylo-hex-3-ulonolactone <=> H+ + ascorbate
|
1.1.3.8
L-gulonolactone oxidase
|
–
|
|
KEGG:
R00647
MetaCyc:
RXN-8784
|
|
|
|
4''-Dephosphorylated_1-PEtN-KDO-lipid_A + H2O <=> H._pylori_KDO-lipid_A + (R)-3-(Tetradecanoyloxy)hexadecanoic_acid
|
3.1.1
|
–
|
|
KEGG:
R12204
|
|
|
|
biphenyl + O2 + NADH + H+ <=> cis-2,3-dihydro-2,3-dihydroxybiphenyl + NAD+
|
1.14.12.18
biphenyl 2,3-dioxygenase
1.14.12.22
carbazole 1,9a-dioxygenase
|
–
–
|
|
BRENDA:
BR29137
KEGG:
R05263
MetaCyc:
1.14.12.18-RXN
|
|
|
|
N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O <=> 4-amino-5-aminomethyl-2-methylpyrimidine + formate
|
3.5.1
|
–
|
|
KEGG:
R11313
MetaCyc:
RXN-12612
|
|
|
|
S-adenosyl-L-methionine + 2-methyl-6-all-trans-nonaprenylbenzene-1,4-diol <=> plastoquinol + S-adenosyl-L-homocysteine + H+
|
2.1.1.295
2-methyl-6-phytyl-1,4-hydroquinone methyltransferase
|
–
|
|
BRENDA:
BR50940
KEGG:
R10709
MetaCyc:
RXN-2762
|
|
|
|
n UDP-D-galacturonate <=> n UDP + Pectin
|
2.4.1.43
polygalacturonate 4-alpha-galacturonosyltransferase
|
–
|
|
KEGG:
R05191
|
|
|
|
adenosine + phosphate <=> adenine + alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
2.4.2.44
S-methyl-5'-thioinosine phosphorylase
|
–
–
–
|
|
BRENDA:
BS323170
KEGG:
R01561
MetaCyc:
ADENPHOSPHOR-RXN
SABIO-RK:
133
|
|
|
|
Inosine + H2O <=> D-ribose + hypoxanthine
|
3.2.2.1
purine nucleosidase
3.2.2.2
inosine nucleosidase
3.2.2.7
adenosine nucleosidase
3.2.2.8
ribosylpyrimidine nucleosidase
|
–
–
–
–
|
|
BRENDA:
BR16042
KEGG:
R01770
MetaCyc:
INOSINE-NUCLEOSIDASE-RXN
|
|
|
|
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-[alpha-L-Fuc-(1->3)]-D-GlcNAc + H2O <=> alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-1-Asn + N-acetyl-D-glucosamine
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
KEGG:
R11317
|
|
|
|
tryparedoxin + ROOH <=> Tryparedoxin_disulfide + H2O + rhodopsin
|
1.11.1
|
–
|
|
KEGG:
R08360
|
|
|
|
retinoic_acid + NADPH + H+ + O2 <=> all-trans-4-Hydroxyretinoic_acid + NADP+ + H2O
|
1.14.13
1.14.14
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
|
KEGG:
R08392
SABIO-RK:
7142
|
|
|
|
(S)-malate + NADP+ <=> H+ + NADPH + oxaloacetate
|
1.1.1.299
malate dehydrogenase [NAD(P)+]
1.1.1.37
malate dehydrogenase
1.1.1.375
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.81
hydroxypyruvate reductase
1.1.1.82
malate dehydrogenase (NADP+)
|
–
–
–
–
–
–
|
|
BRENDA:
BR29342;
BS188648
KEGG:
R00343
MetaCyc:
MALATE-DEHYDROGENASE-NADP+-RXN;
RXN-10813
SABIO-RK:
143
|
|
|
|
(8S)-3,8-cyclo-7,8-dihydroguanosine_5''-triphosphate <=> cyclic_pyranopterin_phosphate + diphosphate
|
4.6.1.17
cyclic pyranopterin monophosphate synthase
|
–
|
|
BRENDA:
BR51778
KEGG:
R11372
MetaCyc:
RXN-17809
|
|
|
|
UDP-N-acetylmuramate + NAD+ <=> UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADH + H+
|
1.3.1.98
UDP-N-acetylmuramate dehydrogenase
|
–
|
|
KEGG:
R03191
|
|
|
|
AMP + diphosphate <=> adenine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
|
BRENDA:
BR47515
KEGG:
R00190
MetaCyc:
ADENPRIBOSYLTRAN-RXN
SABIO-RK:
80
|
|
|
|
UDP-glucose + D-fructose <=> sucrose + UDP + H+
|
2.4.1.13
sucrose synthase
2.4.1.14
sucrose-phosphate synthase
|
–
–
|
|
BRENDA:
BS322050
KEGG:
R00806;
R06036
MetaCyc:
SUCROSE-SYNTHASE-RXN
SABIO-RK:
590
|
|
|
|
alpha-D-ribose_1-methylphosphonate_5-triphosphate + H2O <=> alpha-D-ribose_1-methylphosphonate_5-phosphate + diphosphate + H+
|
3.6.1.63
alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
|
–
|
|
BRENDA:
BR50324
KEGG:
R10186
MetaCyc:
RXN0-6733
|
|
|
|
S-adenosyl-L-methionine + 8-demethylnovobiocic_acid <=> S-adenosyl-L-homocysteine + novobiocic_acid + H+
|
2.1.1.284
8-demethylnovobiocic acid C8-methyltransferase
|
–
|
|
BRENDA:
BR50630
KEGG:
R10454
MetaCyc:
RXN-14543
|
|
|
|
2-hydroxyhepta-2,4-dienedioate + H2O <=> 2,4-Dihydroxyhept-2-enedioate
|
4.2.1
|
–
|
|
KEGG:
R06897
|
|
|
|
L-tyrosine + tetrahydrobiopterin + O2 <=> L-Dopa + 4a-hydroxytetrahydrobiopterin
|
1.14.16.2
tyrosine 3-monooxygenase
|
–
|
|
BRENDA:
BS377086
KEGG:
R07212
SABIO-RK:
7156
|
|
|
|
(3S)-2,3-epoxy-2,3-dihydrosqualene <=> lanosterol
|
5.4.99.17
squalene---hopene cyclase
5.4.99.7
lanosterol synthase
|
–
–
|
|
BRENDA:
BR254
KEGG:
R03199
MetaCyc:
LANOSTEROL-SYNTHASE-RXN
SABIO-RK:
3027
|
|
|
|
UDP-2-acetamido-2-deoxy-alpha-D-glucuronate <=> UDP-N-acetyl-D-galactosaminuronate
|
5.1.3
|
–
|
|
KEGG:
R08706
MetaCyc:
RXN-16259
|
|
|
|
folate + NADPH <=> tetrahydrofolate + NADP+
|
1.5.1.3
dihydrofolate reductase
1.5.1.33
pteridine reductase
1.5.1.34
6,7-dihydropteridine reductase
|
–
–
–
|
|
BRENDA:
BS259283
KEGG:
R00940
SABIO-RK:
1256
|
|
|
|
N2 + H2O + 2 ferricytochrome_c <=> N2O + 2 ferricytochrome_c + 2 H+
|
1.7.2.4
nitrous-oxide reductase
|
–
|
|
BRENDA:
BR36994
KEGG:
R02804
|
|
|
|
H2O + anserine <=> 1-methylhistidine + beta-Alanine
|
3.4.13.20
beta-Ala-His dipeptidase
3.4.13.5
Xaa-methyl-His dipeptidase
|
–
–
|
|
BRENDA:
BS36422
KEGG:
R03288
MetaCyc:
X-METHYL-HIS-DIPEPTIDASE-RXN
|
|
|
|
4-hydroxybutyrate + NAD+ <=> succinate_semialdehyde + NADH + H+
|
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.61
4-hydroxybutyrate dehydrogenase
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.B47
|
–
–
–
–
–
|
|
BRENDA:
BR29325
KEGG:
R01644
MetaCyc:
4-HYDROXYBUTYRATE-DEHYDROGENASE-RXN
SABIO-RK:
1781
|
|
|
|
D-glucose_6-phosphate <=> beta-D-fructose_6-phosphate
|
2.6.1.16
glutamine---fructose-6-phosphate transaminase (isomerizing)
5.3.1.8
mannose-6-phosphate isomerase
5.3.1.9
glucose-6-phosphate isomerase
|
–
–
–
|
|
BRENDA:
BR240
KEGG:
R00771
MetaCyc:
PGLUCISOM-RXN
SABIO-RK:
1123;
8448
|
|
|
|
fumiquinazoline_F-indoline-2,3''-diol + L-alanine + ATP <=> Fumiquinazoline_A + AMP + diphosphate + H2O + H+
|
6.3.2
|
–
|
|
KEGG:
R12419
MetaCyc:
RXN-15748
|
|
|
|
S-adenosyl-L-methionine + 3''-O-demethyl-staurosporine <=> staurosporine + S-adenosyl-L-homocysteine + H+
|
2.1.1.139
3'-demethylstaurosporine O-methyltransferase
|
–
|
|
BRENDA:
BR29466
KEGG:
R05757
MetaCyc:
2.1.1.139-RXN
|
|
|
|
Caffeine + NADH + O2 + H+ <=> paraxanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
|
–
–
|
|
BRENDA:
BS411830
KEGG:
R07954
MetaCyc:
RXN-13106_WOP
|
|
|
|
a_D-amino_acid + pyruvate <=> a_2-oxo_carboxylate + D-alanine
|
2.6.1.21
D-amino-acid transaminase
|
–
|
|
KEGG:
R01344
|
|
|
|
2-hydroxy-2,4-hexadienedioate <=> 4-oxalocrotonate
|
5.3.2.6
2-hydroxymuconate tautomerase
5.3.2.M1
|
–
–
|
|
BRENDA:
BR50210;
BS419260;
BS419261;
BS419897
KEGG:
R03966
MetaCyc:
RXN-12354;
RXN-8529
SABIO-RK:
3703
|
|
|
|
S-adenosyl-L-methionine + dihydrosterigmatocystin <=> H+ + 8-O-methyldihydrosterigmatocystin + S-adenosyl-L-homocysteine
|
2.1.1.110
sterigmatocystin 8-O-methyltransferase
|
–
|
|
BRENDA:
BR50532
KEGG:
R10307
MetaCyc:
RXN-9501
|
|
|
|
CoA + acetate + ATP <=> acetyl-CoA + diphosphate + AMP
|
6.2.1.1
acetate---CoA ligase
6.2.1.17
propionate---CoA ligase
6.2.1.36
3-hydroxypropionyl-CoA synthase
|
–
–
–
|
|
BRENDA:
BR60
KEGG:
R00235
MetaCyc:
ACETATE--COA-LIGASE-RXN
SABIO-RK:
179
|
|
|
|
D-arabitol + NADP+ <=> D-xylulose + NADPH + H+
|
1.1.1.14
L-iditol 2-dehydrogenase
1.1.1.287
D-arabinitol dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BR48609
KEGG:
R07143
MetaCyc:
RXN-7971
SABIO-RK:
6502
|
|
|
|
(Z)-pent-1-ene-1,2,5-tricarboxylate + H2O <=> (-)-threo-iso(homo)2citrate
|
4.2.1.114
methanogen homoaconitase
|
–
|
|
BRENDA:
BS421927
KEGG:
R10393
MetaCyc:
R213-RXN
|
|
|
|
sarcosine + H2O + flavin <=> glycine + formaldehyde + reduced_flavodoxin
|
1.5.8.3
sarcosine dehydrogenase
|
–
|
|
BRENDA:
BR36913
KEGG:
R00611
|
|
|
|
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose + H2O <=> H+ + 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose + UDP
|
3.6.1.57
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase
|
–
|
|
BRENDA:
BR49920
KEGG:
R09834
MetaCyc:
RXN-10001
|
|
|
|
alpha-D-GlcNAc-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + N-acetyl-D-glucosamine
|
3.2.1.50
alpha-N-acetylglucosaminidase
|
–
|
|
KEGG:
R07816
|
|
|
|
6-keto-prostaglandin_F1alpha + acceptor <=> 6-ketoprostaglandin_E1 + reduced_acceptor
|
not assigned
|
–
|
|
KEGG:
R05059
|
|
|
|
5,6-dihydrouracil + NADP+ <=> Uracil + NADPH + H+
|
1.3.1.1
dihydropyrimidine dehydrogenase (NAD+)
1.3.1.2
dihydropyrimidine dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BR33762
KEGG:
R00978
MetaCyc:
1.3.1.2-RXN
SABIO-RK:
471
|
|
|
|
5beta-cholestane-3alpha,7alpha,12alpha-triol + NADP+ <=> 7alpha,12alpha-dihydroxy-5beta-cholestan-3-one + NADPH + H+
|
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
|
–
–
|
|
BRENDA:
BS422687
KEGG:
R04825
MetaCyc:
RXN-9796
SABIO-RK:
4470
|
|
|
|
D-glucose <=> D-glucose
|
5.1.3.21
maltose epimerase
5.1.3.3
aldose 1-epimerase
|
–
–
|
|
BRENDA:
BR197
KEGG:
R01602
MetaCyc:
ALDOSE-1-EPIMERASE-RXN;
RXN-14352;
RXN0-7077;
TRANS-RXN0-574
SABIO-RK:
1750
|
|
|
|
CMP-N-acetylneuraminate + Galactosylgloboside <=> monosialylgalactosylgloboside + CMP + H+
|
2.4.99.4
beta-galactoside alpha-2,3-sialyltransferase
|
–
|
|
KEGG:
R05967
MetaCyc:
RXN-18299
|
|
|
|
H+ + precorrin-8X <=> Hydrogenobyrinate
|
5.4.99.61
precorrin-8X methylmutase
|
–
|
|
BRENDA:
BR16
KEGG:
R05177
MetaCyc:
5.4.1.2-RXN
SABIO-RK:
4794
|
|
|
|
D-xylose + NAD+ <=> D-xylono-1,5-lactone + NADH + H+
|
1.1.1.121
aldose 1-dehydrogenase (NAD+)
1.1.1.122
D-threo-aldose 1-dehydrogenase
1.1.1.175
D-xylose 1-dehydrogenase
1.1.1.179
D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.18
inositol 2-dehydrogenase
1.1.1.359
aldose 1-dehydrogenase [NAD(P)+]
1.1.1.376
L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.424
D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
1.1.1.47
glucose 1-dehydrogenase [NAD(P)+]
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29235;
BS451059
KEGG:
R01429
MetaCyc:
D-XYLOSE-1-DEHYDROGENASE-RXN;
RXN-14641_WOP
SABIO-RK:
1614
|
|
|
|
H2O + 2-Phosphoglycolate <=> glycolate + phosphate
|
3.1.3.18
phosphoglycolate phosphatase
3.1.3.2
acid phosphatase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.71
2-phosphosulfolactate phosphatase
5.4.2.4
bisphosphoglycerate mutase
|
–
–
–
–
–
|
|
BRENDA:
BR6356
KEGG:
R01334
MetaCyc:
GPH-RXN
SABIO-RK:
433
|
|
|
|
phosphate + thymidine <=> 2-deoxy-alpha-D-ribose_1-phosphate + thymine
|
2.4.2.2
pyrimidine-nucleoside phosphorylase
2.4.2.3
uridine phosphorylase
2.4.2.4
thymidine phosphorylase
|
–
–
–
|
|
BRENDA:
BR47547;
BS355326
KEGG:
R01570
MetaCyc:
THYM-PHOSPH-RXN
SABIO-RK:
79
|
|
|
|
2,4-Diaminopentanoate + H2O + NADP+ <=> (2R)-2-amino-4-oxopentanoate + NH3 + NADPH + H+
|
1.4.1.12
2,4-diaminopentanoate dehydrogenase
|
–
|
|
BRENDA:
BR36860;
BS258906
KEGG:
R04201
MetaCyc:
24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN
|
|
|
|
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + 3-alpha-mycarosylerythronolide_B <=> erythromycin_D + dTDP + H+
|
2.4.1.278
3-alpha-mycarosylerythronolide B desosaminyl transferase
|
–
|
|
BRENDA:
BR49893
KEGG:
R05531
MetaCyc:
RXN-12808
|
|
|
|
H+ + Phosphonopyruvate <=> phosphonoacetaldehyde + CO2
|
4.1.1.82
phosphonopyruvate decarboxylase
|
–
|
|
BRENDA:
BR48645
KEGG:
R04053
MetaCyc:
4.1.1.82-RXN
SABIO-RK:
3786
|
|
|
|
L-arogenate + 2-oxoglutarate <=> prephenate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.78
aspartate---prephenate aminotransferase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
|
|
BRENDA:
BR48630
KEGG:
R07276
MetaCyc:
PREPHENATE-TRANSAMINE-RXN
SABIO-RK:
9205
|
|
|
|
(3R,6Z,9Z,12Z,15Z,18Z)-3-Hydroxytetracosapentaenoyl-CoA + NAD+ <=> (6Z,9Z,12Z,15Z,18Z)-3-Oxotetracosapentaenoyl-CoA + NADH + H+
|
1.1.1
|
–
|
|
KEGG:
R07952
|
|
|
|
UDP-N-acetyl-D-glucosamine <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + H2O
|
4.2.1.115
UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting)
|
–
|
|
BRENDA:
BR49016
KEGG:
R09697
MetaCyc:
RXN-9998
SABIO-RK:
14430
|
|
|
|
phenylacetonitrile + reduced_flavodoxin + O2 <=> (R)-mandelonitrile + flavin + H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
1.14.14.77
phenylacetonitrile alpha-monooxygenase
|
–
–
|
|
BRENDA:
BR52035
KEGG:
R11733
|
|
|
|
ATP + L-glutamine + HCO3- + H2O <=> L-glutamate + Carbamoyl_phosphate + ADP + phosphate + H+
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
|
BRENDA:
BR152
KEGG:
R00575
MetaCyc:
CARBPSYN-RXN
SABIO-RK:
203
|
|
|
|
Carbamate + ATP <=> Carbamoyl_phosphate + ADP
|
2.7.2.2
carbamate kinase
6.3.4.14
biotin carboxylase
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
–
–
|
|
BRENDA:
BR51479
KEGG:
R01395
MetaCyc:
RXN-14196
SABIO-RK:
1589
|
|
|
|
ATP + maltose <=> H+ + ADP + alpha-maltose_1-phosphate
|
2.7.1.175
maltokinase
|
–
|
|
BRENDA:
BR50056
KEGG:
R09945
MetaCyc:
RXN-12960
|
|
|
|
L-arabitol + NAD+ <=> L-xylulose + NADH + H+
|
1.1.1.12
L-arabinitol 4-dehydrogenase
1.1.1.16
galactitol 2-dehydrogenase
1.1.1.56
ribitol 2-dehydrogenase
1.1.1.9
D-xylulose reductase
|
–
–
–
–
|
|
BRENDA:
BR29185
KEGG:
R01903
MetaCyc:
L-ARABINITOL-4-DEHYDROGENASE-RXN
SABIO-RK:
1958
|
|
|
|
L-pipecolic_acid + FAD <=> FADH2 + (S)-2,3,4,5-tetrahydropyridine-2-carboxylate
|
1.5.99.3
L-pipecolate dehydrogenase
|
–
|
|
KEGG:
R02205
|
|
|
|
8-Methyl-6-nonenoic_acid <=> (6E)-8-methylnon-6-enoyl-CoA
|
not assigned
|
–
|
|
KEGG:
R12628
|
|
|
|
N-acetyl-D-mannosamine <=> N-acetyl-D-glucosamine
|
5.1.3.8
N-acylglucosamine 2-epimerase
|
–
|
|
BRENDA:
BS368625
KEGG:
R01207
MetaCyc:
RXN-16006
SABIO-RK:
1441
|
|
|
|
3-Fluorobenzoate + NADH + H+ + O2 <=> 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
|
1.14.12.10
benzoate 1,2-dioxygenase
|
–
|
|
KEGG:
R08109
|
|
|
|
L-tyrosine + pyruvate <=> 4-hydroxyphenylpyruvate + L-alanine
|
2.6.1.12
alanine---oxo-acid transaminase
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.5
tyrosine transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.58
phenylalanine(histidine) transaminase
|
–
–
–
–
–
|
|
BRENDA:
BS353950
KEGG:
R09254
MetaCyc:
RXN3O-4157
SABIO-RK:
9834
|
|
|
|
dopamine + 4-hydroxyphenylacetaldehyde <=> H2O + (S)-norcoclaurine
|
4.2.1.78
(S)-norcoclaurine synthase
|
–
|
|
BRENDA:
BR455
KEGG:
R04305
MetaCyc:
S-NORLAUDANOSOLINE-SYNTHASE-RXN
|
|
|
|
ATP + GMP <=> ADP + GDP
|
2.7.4.8
guanylate kinase
|
–
|
|
BRENDA:
BR47853
KEGG:
R00332
MetaCyc:
GUANYL-KIN-RXN
SABIO-RK:
77
|
|
|
|
prostaglandin_H2 <=> prostaglandin_I2
|
5.3.99.4
prostaglandin-I synthase
|
–
|
|
BRENDA:
BR6442
KEGG:
R02267
MetaCyc:
PROSTAGLANDIN-I-SYNTHASE-RXN
SABIO-RK:
2234
|
|
|
|
salutaridinol + acetyl-CoA <=> 7-O-acetylsalutaridinol + CoA
|
2.3.1.150
salutaridinol 7-O-acetyltransferase
|
–
|
|
BRENDA:
BR1626
KEGG:
R04723
MetaCyc:
2.3.1.150-RXN
|
|
|
|
uric_acid_ribonucleoside + phosphate <=> alpha-D-ribose_1-phosphate + Urate
|
2.4.2.16
urate-ribonucleoside phosphorylase
|
–
|
|
BRENDA:
BR47658;
BS356200
KEGG:
R02646
MetaCyc:
URATE-RIBONUCLEOTIDE-PHOSPHORYLASE-RXN
|
|
|
|
5-Aminopentanoate + 2-oxoglutarate <=> L-glutamate + 5-Oxopentanoate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.48
5-aminovalerate transaminase
|
–
–
–
|
|
BRENDA:
BR47695
KEGG:
R02274
MetaCyc:
VAGL-RXN
|
|
|
|
S-adenosyl-L-methionine + L-adrenaline <=> metanephrine + S-adenosyl-L-homocysteine + H+
|
2.1.1.6
catechol O-methyltransferase
|
–
|
|
BRENDA:
BS289662
KEGG:
R02920
MetaCyc:
RXN-10909
SABIO-RK:
2779
|
|
|
|
L-glutamine + H2O <=> L-glutamate + NH3
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.14
glutamate synthase (NADH)
1.4.7.1
glutamate synthase (ferredoxin)
2.3.2.2
gamma-glutamyltransferase
2.4.2
2.4.2.14
amidophosphoribosyltransferase
3.4.11.17
tryptophanyl aminopeptidase
3.5.1.1
asparaginase
3.5.1.2
glutaminase
3.5.1.38
glutamin-(asparagin-)ase
3.5.1.43
peptidyl-glutaminase
3.5.1.44
protein-glutamine glutaminase
4.3.1.B2
4.3.2.10
imidazole glycerol-phosphate synthase
4.3.3.6
pyridoxal 5'-phosphate synthase (glutamine hydrolysing)
6.3.4.2
CTP synthase (glutamine hydrolysing)
6.3.5.13
lipid II isoglutaminyl synthase (glutamine-hydrolysing)
6.3.5.2
GMP synthase (glutamine-hydrolysing)
6.3.5.4
asparagine synthase (glutamine-hydrolysing)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
6.3.5.6
asparaginyl-tRNA synthase (glutamine-hydrolysing)
6.3.5.7
glutaminyl-tRNA synthase (glutamine-hydrolysing)
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR22683
KEGG:
R00256
MetaCyc:
GLUTAMIN-RXN
SABIO-RK:
762
|
|
|
|
D-malate <=> H2O + Maleate
|
4.2.1.31
maleate hydratase
4.2.1.36
homoaconitate hydratase
|
–
–
|
|
BRENDA:
BR411
KEGG:
R02419
MetaCyc:
MALEATE-HYDRATASE-RXN
SABIO-RK:
2357
|
|
|
|
all-trans-zeta-carotene + reduced_acceptor + O2 <=> all-trans-neurosporene + A + H2O
|
1.3.5.6
9,9'-dicis-zeta-carotene desaturase
1.3.99.26
all-trans-zeta-carotene desaturase
1.3.99.28
phytoene desaturase (neurosporene-forming)
1.3.99.30
phytoene desaturase (3,4-didehydrolycopene-forming)
1.3.99.31
phytoene desaturase (lycopene-forming)
|
–
–
–
–
–
|
|
BRENDA:
BS402980
KEGG:
R04798
|
|
|
|
isopenicillin_N + acyl-CoA + H2O <=> penicillin + CoA + L-2-aminoadipate
|
2.3.1.164
isopenicillin-N N-acyltransferase
|
–
|
|
KEGG:
R06361
|
|
|
|
phosphatidylcholine + H2O <=> lysophosphatidylcholine + linolenic_acid
|
3.1.1.4
phospholipase A2
|
–
|
|
KEGG:
R07859
|
|
|
|
L-proline + pC3'p + ATP <=> (L-prolyl)-[peptidyl-carrier_protein] + AMP + diphosphate
|
6.2.1.53
L-proline---[L-prolyl-carrier protein] ligase
|
–
|
|
KEGG:
R06746
|
|
|
|
H2O + Phosphonoacetate <=> H+ + phosphate + acetate
|
3.11.1.2
phosphonoacetate hydrolase
|
–
|
|
BRENDA:
BR2410
KEGG:
R00318
MetaCyc:
3.11.1.2-RXN
|
|
|
|
N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine + H2O <=> ganglioside_GM3 + N-acetyl-D-galactosamine
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
KEGG:
R06004
|
|
|
|
campesterol + O2 + reduced_acceptor <=> 6alpha-Hydroxycampestanol + H2O + acceptor
|
1.14.99
|
–
|
|
KEGG:
R07467
MetaCyc:
RXN-713
|
|
|
|
Inosine + phosphate <=> hypoxanthine + alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.15
guanosine phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
2.4.2.3
uridine phosphorylase
2.4.2.44
S-methyl-5'-thioinosine phosphorylase
|
–
–
–
–
–
|
|
BRENDA:
BS323149
KEGG:
R01863
MetaCyc:
INOPHOSPHOR-RXN
SABIO-RK:
125
|
|
|
|
O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + ferricytochrome_b5 + O2 + H+ <=> ethanolamine_plasmalogen + ferricytochrome_b5 + H2O
|
1.14.19.77
plasmanylethanolamine desaturase
|
–
|
|
BRENDA:
BR40390
KEGG:
R04571
MetaCyc:
RXN-17732
|
|
|
|
D-glucose_6-phosphate + acetyl-CoA <=> N-acetyl-D-glucosamine_6-phosphate + H+ + CoA
|
2.3.1.4
glucosamine-phosphate N-acetyltransferase
|
–
|
|
BRENDA:
BR44040
KEGG:
R02058
MetaCyc:
GLUCOSAMINEPNACETYLTRANS-RXN
SABIO-RK:
2075
|
|
|
|
S-adenosyl-L-methionine + N-acetyl-O-demethylpuromycin <=> H+ + N-acetylpuromycin + S-adenosyl-L-homocysteine
|
2.1.1.38
O-demethylpuromycin O-methyltransferase
|
–
|
|
BRENDA:
BS319688
KEGG:
R05676
MetaCyc:
RXN-9452
|
|
|
|
(3R,6Z,9Z,12Z,15Z,18Z,21Z)-3-Hydroxytetracosahexaenoyl-CoA <=> (2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA + H2O
|
4.2.1.119
enoyl-CoA hydratase 2
|
–
|
|
KEGG:
R07935
|
|
|
|
tetrahydrobiopterin + NADP+ <=> (6R)-L-erythro-6,7-dihydrobiopterin + NADPH + H+
|
1.5.1.3
dihydrofolate reductase
1.5.1.33
pteridine reductase
1.5.1.34
6,7-dihydropteridine reductase
|
–
–
–
|
|
BRENDA:
BS319540;
BS388536
KEGG:
R01794;
R11765
MetaCyc:
RXN-14245
SABIO-RK:
1883;
7757
|
|
|
|
H+ + alpha-D-glucuronic_acid_1-phosphate + UTP <=> UDP-glucuronate + diphosphate
|
2.7.7.44
glucuronate-1-phosphate uridylyltransferase
2.7.7.64
UTP-monosaccharide-1-phosphate uridylyltransferase
|
–
–
|
|
BRENDA:
BR48084;
BS359895
KEGG:
R01381
MetaCyc:
2.7.7.44-RXN
SABIO-RK:
1582
|
|
|
|
prostaglandin_F2alpha + NADP+ <=> prostaglandin_H2 + NADPH + H+
|
1.1.1
1.1.1.188
prostaglandin-F synthase
1.1.1.189
prostaglandin-E2 9-reductase
1.6.99.1
NADPH dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BS257134
KEGG:
R02264
MetaCyc:
RXN-21136
SABIO-RK:
7732
|
|
|
|
ubiquinone + D-glucose <=> ubiquinol + D-glucono-1,5-lactone
|
1.1.5.2
glucose 1-dehydrogenase (PQQ, quinone)
1.1.5.9
glucose 1-dehydrogenase (FAD, quinone)
|
–
–
|
|
BRENDA:
BR47599;
BS370875;
BS439425
KEGG:
R06620
MetaCyc:
RXN0-6373
|
|
|
|
UDP-N-acetyl-D-glucosamine + glycoprotein_N-acetyl-D-galactosamine <=> N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-alpha-D-galactosaminyl-R + H+ + UDP
|
2.4.1.147
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase
|
–
|
|
KEGG:
R03513;
R05909
MetaCyc:
2.4.1.147-RXN
|
|
|
|
chlorophyllide_a + O2 + NADPH + H+ <=> 7-hydroxychlorophyllide_a + H2O + NADP+
|
1.14.13.122
chlorophyllide-a oxygenase
|
–
|
|
BRENDA:
BR48662
KEGG:
R08203
MetaCyc:
RXN-7676
|
|
|
|
UDP-glucose + beta-D-gentiobiosyl_beta-D-glucosyl_crocetin <=> crocin + UDP + H+
|
2.4.1.330
beta-D-glucosyl crocetin beta-1,6-glucosyltransferase
|
–
|
|
BRENDA:
BR51085
KEGG:
R10990
MetaCyc:
RXN-8476
|
|
|
|
L-homoserine + acetyl-CoA <=> O-acetyl-L-homoserine + CoA
|
2.3.1.31
homoserine O-acetyltransferase
|
–
|
|
BRENDA:
BR44031
KEGG:
R01776
MetaCyc:
HOMOSERINE-O-ACETYLTRANSFERASE-RXN
SABIO-RK:
1869
|
|
|
|
propionyl-CoA + H2O + glyoxylate <=> 2-hydroxyglutarate + H+ + CoA
|
2.3.3.11
2-hydroxyglutarate synthase
|
–
|
|
BRENDA:
BR44120
KEGG:
R00932
MetaCyc:
HYDGLUTSYN-RXN
|
|
|
|
ATP + Urea + HCO3- + H+ <=> ADP + phosphate + allophanate
|
6.3.4.6
urea carboxylase
|
–
|
|
BRENDA:
BR143
KEGG:
R00774
SABIO-RK:
1126
|
|
|
|
behenoyl-CoA + NADP+ <=> trans-docos-2-enoyl-CoA + NADPH + H+
|
1.3.1.93
very-long-chain enoyl-CoA reductase
|
–
|
|
BRENDA:
BR50149
KEGG:
R10828
MetaCyc:
RXN-13307
|
|
|
|
N,N''-diacetylchitobiose + H2O <=> N-acetyl-D-glucosamine
|
3.2.1.14
chitinase
3.2.1.169
protein O-GlcNAcase
3.2.1.21
beta-glucosidase
3.2.1.52
beta-N-acetylhexosaminidase
3.5.1.41
chitin deacetylase
|
–
–
–
–
–
|
|
BRENDA:
BS259847;
BS259849;
BS412085
KEGG:
R00022;
R06141
MetaCyc:
RXN-12625
SABIO-RK:
615
|
|
|
|
S-adenosyl-L-methionine + 1-hydroxy-3,4-didehydrolycopene <=> 1-methoxy-3,4-didehydrolycopene + S-adenosyl-L-homocysteine + H+
|
2.1.1
2.1.1.210
demethylspheroidene O-methyltransferase
|
–
–
|
|
BRENDA:
BS415221
KEGG:
R07521
MetaCyc:
RXN-11648
|
|
|
|
D-glycerate + ATP <=> H+ + 3-phospho-D-glycerate + ADP
|
2.7.1.165
glycerate 2-kinase
2.7.1.31
glycerate 3-kinase
|
–
–
|
|
BRENDA:
BR47771;
BS370516;
BS396474
KEGG:
R01514
MetaCyc:
GLY3KIN-RXN
SABIO-RK:
428
|
|
|
|
chondroitin_D-glucuronate <=> dermatan_L-iduronate
|
5.1.3.19
chondroitin-glucuronate 5-epimerase
|
–
|
|
BRENDA:
BR194
KEGG:
R04104
|
|
|
|
campesterol + NADPH + H+ + O2 <=> (22S)-22-hydroxycampesterol + NADP+ + H2O
|
1.14.13
1.14.99.B1
|
–
–
|
|
BRENDA:
BS396650
KEGG:
R07445
SABIO-RK:
12698
|
|
|
|
acetyl-CoA + GDP-4-amino-4,6-dideoxy-alpha-D-mannose <=> CoA + GDP-4-acetamido-4,6-dideoxy-alpha-D-mannose + H+
|
2.3.1.227
GDP-perosamine N-acetyltransferase
|
–
|
|
BRENDA:
BR50642
KEGG:
R10514
MetaCyc:
RXN-14698
|
|
|
|
2,5-dichloromaleylacetate + NADH <=> 2-chloro-3-oxohexanedioic_acid + NAD+ + Cl-
|
1.3.1.32
maleylacetate reductase
|
–
|
|
BRENDA:
BS258489
KEGG:
R06848
|
|
|
|
3''-Keto-3''-deoxy-ATP <=> 3''-Keto-3''-deoxy-AMP + diphosphate
|
3
|
–
|
|
KEGG:
R05669
|
|
|
|
O-succinyl-L-homoserine + Sulfide <=> H+ + L-homocysteine + succinate
|
2.5.1
2.5.1.48
cystathionine gamma-synthase
2.5.1.49
O-acetylhomoserine aminocarboxypropyltransferase
|
–
–
–
|
|
BRENDA:
BS354328
KEGG:
R01288
MetaCyc:
RXN-9384
|
|
|
|
L-alanine + H2O + NAD+ <=> pyruvate + NH3 + NADH + H+
|
1.4.1.1
alanine dehydrogenase
1.4.1.23
valine dehydrogenase (NAD+)
1.4.1.3
glutamate dehydrogenase [NAD(P)+]
1.4.1.8
valine dehydrogenase (NADP+)
1.4.1.9
leucine dehydrogenase
|
–
–
–
–
–
|
|
BRENDA:
BR33794
KEGG:
R00396
MetaCyc:
ALANINE-DEHYDROGENASE-RXN
SABIO-RK:
857
|
|
|
|
UDP-glucuronate + [protein]-3-O-(beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl)-L-serine <=> UDP + [protein]-3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-serine
|
2.4.1.135
galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase
|
–
|
|
BRENDA:
BR36937;
BS386743
KEGG:
R04607;
R05928
|
|
|
|
(22R)-22-hydroxycholesterol + O2 + reduced_adrenodoxin + H+ <=> (20R,22R)-20,22-dihydroxy-cholesterol + H2O + oxidized_ferredoxin
|
1.14.15.6
cholesterol monooxygenase (side-chain-cleaving)
|
–
|
|
BRENDA:
BR50361
KEGG:
R04855
MetaCyc:
RXN66-338
|
|
|
|
zeaxanthin + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> antheraxanthin + oxidized_ferredoxin + H2O
|
1.14.15.21
zeaxanthin epoxidase
|
–
|
|
BRENDA:
BR48604
KEGG:
R06946
MetaCyc:
RXN-7978
|
|
|
|
17alpha-hydroxyprogesterone + reduced_flavodoxin + O2 <=> 11-deoxycortisol + flavin + H2O
|
1.14.14.16
steroid 21-monooxygenase
|
–
|
|
BRENDA:
BS427270
KEGG:
R03326
|
|
|
|
choline + NAD+ <=> Betaine_aldehyde + NADH + H+
|
1.1.1
1.1.1.1
alcohol dehydrogenase
|
–
–
|
|
KEGG:
R08557
MetaCyc:
RXN-6021
|
|
|
|
dAMP + H2O <=> 2''-deoxyadenosine + phosphate
|
3.1.3.2
acid phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.89
5'-deoxynucleotidase
|
–
–
–
–
|
|
BRENDA:
BS391800
KEGG:
R02088
MetaCyc:
RXN-14161
SABIO-RK:
282
|
|
|
|
pyruvate + trans-2-octenal + H+ <=> (S)-3-acetyloctanal + CO2
|
2.2.1.12
3-acetyloctanal synthase
|
–
|
|
BRENDA:
BR51185
KEGG:
R11141
MetaCyc:
RXN-15769
|
|
|
|
(1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + O2 + H+ <=> (1R,10aS)-1,4,10,10a-tetrahydrophenazine-1-carboxylate + H2O2 + CO2
|
not assigned
|
–
|
|
KEGG:
R11570
MetaCyc:
RXN-17689
|
|
|
|
N6-acetyl-L-lysine + H2O <=> L-lysine + acetate
|
3.5.1.17
acyl-lysine deacylase
|
–
|
|
BRENDA:
BS116187
KEGG:
R00458
|
|
|
|
cholesterol + O2 + 2 H+ + 2 reduced_ferredoxin <=> 20alpha-hydroxycholesterol + H2O + 2 oxidized_ferredoxin
|
1.14.15.6
cholesterol monooxygenase (side-chain-cleaving)
|
–
|
|
KEGG:
R01454
|
|
|
|
S-adenosyl-L-methionine + dTDP-4-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranose <=> S-adenosyl-L-homocysteine + dTDP-alpha-D-forosamine + H+
|
2.1.1.324
dTDP-4-amino-2,3,4,6-tetradeoxy-D-glucose N,N-dimethyltransferase
|
–
|
|
BRENDA:
BR51593
KEGG:
R08932
MetaCyc:
RXN-17384
|
|
|
|
UDP-MurNAc-L-Ala-L-Glu + ATP + H2O <=> UDP-MurNAc-L-Ala-D-Glu + AMP + diphosphate + H+
|
5.1.1.23
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase
|
–
|
|
BRENDA:
BR52451
KEGG:
R12271
MetaCyc:
RXN-19252
|
|
|
|
gibberellin_A12 <=> Gibberellin_A53
|
not assigned
|
–
|
|
KEGG:
R06329
|
|
|
|
[glycine_cleavage_system_H]-N6-octanoyl-L-lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 8 H+ <=> dihydrolipoylprotein + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe2+ + 2 L-methionine + 2 5''-Deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
|
KEGG:
R12424
|
|
|
|
phosphatidylinositol_4,5-bisphosphate + ATP <=> phosphatidylinositol_3,4,5-trisphosphate + ADP + H+
|
2.7.1.137
phosphatidylinositol 3-kinase
2.7.1.151
inositol-polyphosphate multikinase
2.7.1.153
phosphatidylinositol-4,5-bisphosphate 3-kinase
|
–
–
–
|
|
BRENDA:
BR36945
KEGG:
R04545
MetaCyc:
2.7.1.153-RXN
SABIO-RK:
4221
|
|
|
|
D-galactaro-1,5-lactone <=> D-galactaro-1,4-lactone
|
5.4.1.4
D-galactarolactone isomerase
|
–
|
|
BRENDA:
BR51428
KEGG:
R10846
MetaCyc:
RXN-15901
|
|
|
|
geranyl_diphosphate + H2O <=> geraniol + diphosphate
|
3.1.7.11
geranyl diphosphate diphosphatase
3.1.7.3
monoterpenyl-diphosphatase
4.2.3.104
alpha-humulene synthase
|
–
–
–
|
|
BRENDA:
BR50059
KEGG:
R08396
MetaCyc:
RXN-17103;
RXN-8618
SABIO-RK:
12967
|
|
|
|
19-hydroxytestosterone + O2 + reduced_flavodoxin <=> 19-oxotestosterone + 2 H2O + flavin
|
1.14.14.14
aromatase
|
–
|
|
BRENDA:
BR50744
KEGG:
R04761
|
|
|
|
H+ + salicylate + O2 + NADH <=> catechol + CO2 + H2O + NAD+
|
1.14.13.1
salicylate 1-monooxygenase
|
–
|
|
BRENDA:
BR36758
KEGG:
R00818
MetaCyc:
SALICYLATE-1-MONOOXYGENASE-RXN
|
|
|
|
CMP-N-acetylneuraminate + GT1c <=> CMP + GQ1c
|
2.4.99
|
–
|
|
KEGG:
R05954
|
|
|
|
D-galacturonate + NADH + H+ <=> L-galactonate + NAD+
|
1.1.1
1.1.1.365
D-galacturonate reductase
|
–
–
|
|
BRENDA:
BS426194
KEGG:
R10565
|
|
|
|
2-oxoisovalerate + Enzyme_N6-(lipoyl)lysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylpropanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
KEGG:
R01701
|
|
|
|
1-methoxy-1'-hydroxy-3,4-didehydrolycopene <=> 1-methoxy-1'-hydroxy-3,4,3',4'-tetradehydrolycopene
|
1.3.99.27
1-hydroxycarotenoid 3,4-desaturase
|
–
|
|
KEGG:
R07523
|
|
|
|
(R)-2,3-dihydroxy-3-methylbutanoate + NADP+ <=> (S)-2-Hydroxy-2-methyl-3-oxobutanoate + NADPH + H+
|
1.1.1.383
ketol-acid reductoisomerase [NAD(P)+]
1.1.1.86
ketol-acid reductoisomerase (NADP+)
|
–
–
|
|
BRENDA:
BR47598
KEGG:
R04439
MetaCyc:
ACETOLACTREDUCTOISOM-RXN;
RXN-16061
SABIO-RK:
4125
|
|
|
|
H2O + 5,6-dihydrouracil <=> H+ + N-Carbamoyl-beta-alanine
|
3.5.2.16
maleimide hydrolase
3.5.2.2
dihydropyrimidinase
|
–
–
|
|
BRENDA:
BR22718
KEGG:
R02269
MetaCyc:
DIHYDROPYRIMIDINASE-RXN
SABIO-RK:
503
|
|
|
|
2,3-Dihydroxy-p-cumate + O2 <=> 2-Hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate + H+
|
1.13.11
1.13.11.M5
|
–
–
|
|
KEGG:
R05248
MetaCyc:
RXN-666
|
|
|
|
18-hydroxycorticosterone + reduced_adrenodoxin + H+ + O2 <=> H2O + aldosterone + oxidized_ferredoxin
|
1.14.15.4
steroid 11beta-monooxygenase
1.14.15.5
corticosterone 18-monooxygenase
|
–
–
|
|
BRENDA:
BS186783;
BS424454
KEGG:
R03263
MetaCyc:
RXN66-361
|
|
|
|
beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn + H2O <=> N-acetyl-D-glucosamine + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
KEGG:
R09323
|
|
|
|
ureidoacrylate + H2O <=> 2-aminoacrylate + Carbamate + H+
|
3.5.1.110
ureidoacrylate amidohydrolase
|
–
|
|
BRENDA:
BR50061
KEGG:
R09980
MetaCyc:
RXN0-6460
|
|
|
|
methylamine + L-glutamate <=> N-Methyl-L-glutamate + NH3
|
2.1.1.21
methylamine---glutamate N-methyltransferase
|
–
|
|
BRENDA:
BR43888
KEGG:
R01586
MetaCyc:
2.1.1.21-RXN
|
|
|
|
9-cis-violaxanthin + O2 <=> 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12''-apo-beta-caroten-12''-al
|
1.13.11.51
9-cis-epoxycarotenoid dioxygenase
|
–
|
|
BRENDA:
BR48573
KEGG:
R06953
MetaCyc:
RXN-7974
|
|
|
|
D-glycerate + NAD+ <=> H+ + Hydroxypyruvate + NADH
|
1.1.1.237
hydroxyphenylpyruvate reductase
1.1.1.26
glyoxylate reductase
1.1.1.27
L-lactate dehydrogenase
1.1.1.28
D-lactate dehydrogenase
1.1.1.29
glycerate dehydrogenase
1.1.1.60
2-hydroxy-3-oxopropionate reductase
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.81
hydroxypyruvate reductase
1.1.1.92
oxaloglycolate reductase (decarboxylating)
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29292;
BS188418-a
KEGG:
R01388
MetaCyc:
GLYCERATE-DEHYDROGENASE-RXN;
HYDROXYPYRUVATE-REDUCTASE-RXN_WOP
SABIO-RK:
426
|
|
|
|
S-adenosyl-L-methionine + (S)-norcoclaurine <=> H+ + S-adenosyl-L-homocysteine + (S)-Coclaurine
|
2.1.1.128
(RS)-norcoclaurine 6-O-methyltransferase
|
–
|
|
BRENDA:
BS386680
KEGG:
R05123
MetaCyc:
2.1.1.128-RXN
|
|
|
|
5-Aminopentanal <=> DELTA1-piperideine
|
not assigned
|
–
|
|
KEGG:
R06741
|
|
|
|
nicotinate + H2O + Ferrocytochrome <=> 6-Hydroxynicotinate + Ferrocytochrome + H+
|
1.17.2.1
nicotinate dehydrogenase (cytochrome)
|
–
|
|
BRENDA:
BR49237
KEGG:
R09473
MetaCyc:
NICOTINATE-DEHYDROGENASE-RXN
|
|
|
|
propionyl-CoA + L-lactate <=> propionate + lactoyl-CoA
|
2.8.3.1
propionate CoA-transferase
|
–
|
|
KEGG:
R01449
MetaCyc:
PROPIONLACT-RXN
|
|
|
|
2-Hydroxy-2-hydropyrone-4,6-dicarboxylate + NAD+ <=> 2-Pyrone-4,6-dicarboxylate + NADH + H+
|
1.1.1.312
2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
|
–
|
|
KEGG:
R04278
|
|
|
|
dTTP + H2O <=> dTMP + diphosphate + H+
|
3.6.1.12
dCTP diphosphatase
3.6.1.23
dUTP diphosphatase
3.6.1.39
thymidine-triphosphatase
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.65
(d)CTP diphosphatase
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BS141256
KEGG:
R11323
MetaCyc:
RXN0-5107
SABIO-RK:
10421;
10443
|
|
|
|
2''-deoxyguanosine + ATP <=> H+ + dGMP + ADP
|
2.7.1.113
deoxyguanosine kinase
2.7.1.145
deoxynucleoside kinase
2.7.1.20
adenosine kinase
2.7.1.74
deoxycytidine kinase
2.7.1.76
2'-deoxyadenosine kinase
|
–
–
–
–
–
|
|
BRENDA:
BR47726
KEGG:
R01967
MetaCyc:
DEOXYGUANOSINE-KINASE-RXN
SABIO-RK:
324
|
|
|
|
(1R,5aS,6R)-4a-Hydroxy-1,4,4a,5,5a,6,9,10a-octahydrophenazine-1,6-dicarboxylate <=> (1R,6R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate + H2O
|
not assigned
|
–
|
|
KEGG:
R11569
MetaCyc:
RXN-17684
|
|
|
|
Lipoyl-protein + Lipoyl-carrier_protein_E2 <=> glycine_cleavage_system_H + Enzyme_N6-(lipoyl)lysine
|
2.3.1.200
lipoyl amidotransferase
|
–
|
|
KEGG:
R12426
|
|
|
|
1-Alkyl-2-acylglycerol + CDP-ethanolamine <=> O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP + H+
|
2.7.8.1
ethanolaminephosphotransferase
|
–
|
|
KEGG:
R06364
MetaCyc:
RXN-17731
|
|
|
|
(R)-mevalonate + ATP <=> (R)-3-phosphomevalonate + ADP + H+
|
2.7.1.185
mevalonate 3-kinase
|
–
|
|
BRENDA:
BR51126
KEGG:
R10779
MetaCyc:
RXN-15647
|
|
|
|
protein + lipoic_acid + ATP <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + AMP + diphosphate + H+
|
6.3.1.20
lipoate---protein ligase
|
–
|
|
BRENDA:
BR48679;
BS398781
KEGG:
R11143
MetaCyc:
RXN-17127
|
|
|
|
4-hydroxybutyrate + ATP + CoA <=> 4-hydroxybutanoyl-CoA + ADP + phosphate
|
6.2.1.56
4-hydroxybutyrate---CoA ligase (ADP-forming)
|
–
|
|
BRENDA:
BR52705
KEGG:
R10758
MetaCyc:
RXN-18387
|
|
|
|
N-Monomethyl-2-aminoethylphosphonate <=> N-Dimethyl-2-aminoethylphosphonate
|
not assigned
|
–
|
|
KEGG:
R04925
|
|
|
|
D-Aspartate + (D)-4-hydroxy-alpha-ketoglutarate <=> oxaloacetate + L-erythro-4-hydroxyglutamate
|
2.6.1.21
D-amino-acid transaminase
|
–
|
|
KEGG:
R05053
|
|
|
|
H+ + 2,5-diamino-6-(1-D-ribitylamino)-4(3H)-pyrimidinone_5'-phosphate + H2O <=> 5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + NH3
|
3.5.4.26
diaminohydroxyphosphoribosylaminopyrimidine deaminase
|
–
|
|
KEGG:
R09377
MetaCyc:
RXN-10058
|
|
|
|
ascorbate <=> ascorbate + dehydroascorbate + H+
|
1.11.1.11
L-ascorbate peroxidase
|
–
|
|
BRENDA:
BR49584
KEGG:
R03186
MetaCyc:
RXN-3523
|
|
|
|
Theobromine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.179
methylxanthine N3-demethylase
|
–
|
|
BRENDA:
BR50580
KEGG:
R07962
MetaCyc:
RXN-11516
|
|
|
|
nogalaviketone + NADPH + H+ <=> Nogalavinone + NADP+
|
1.1.1
|
–
|
|
KEGG:
R09329
|
|
|
|
(6R)-L-erythro-6,7-dihydrobiopterin <=> dihydrobiopterin
|
not assigned
|
–
|
|
KEGG:
R11767
MetaCyc:
RXN-21000
|
|
|
|
L-arabinopyranose <=> L-ribulose
|
5.3.1.4
L-arabinose isomerase
5.3.1.5
xylose isomerase
|
–
–
|
|
BRENDA:
BR235
KEGG:
R01761
MetaCyc:
ARABISOM-RXN
SABIO-RK:
1860
|
|
|
|
N2-(2-carboxyethyl)-L-arginine + ATP <=> deoxyamidinoproclavaminate + AMP + diphosphate
|
6.3.3.4
(carboxyethyl)arginine beta-lactam-synthase
|
–
|
|
BRENDA:
BR47589
KEGG:
R05467
MetaCyc:
6.3.3.4-RXN
|
|
|
|
trans-2-hexenoyl-CoA + NADPH <=> hexanoyl-CoA + NADP+
|
1.3.1.10
enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.38
trans-2-enoyl-CoA reductase (NADPH)
1.3.1.44
trans-2-enoyl-CoA reductase (NAD+)
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
|
–
–
–
–
|
|
BRENDA:
BS258524
KEGG:
R06985
SABIO-RK:
7658
|
|
|
|
dethiobiotin + Sulfur_donor + 2 S-adenosyl-L-methionine + 2 e- + 2 H+ <=> biotin + 2 L-methionine + 2 5''-Deoxyadenosine
|
2.8.1.6
biotin synthase
|
–
|
|
KEGG:
R01078
|
|
|
|
staurosporine_aglycone + dTDP-L-ristosamine <=> H+ + Holyrine_A + dTDP
|
2.4
2.4.1
|
–
–
|
|
KEGG:
R11122
MetaCyc:
RXN-10931
|
|
|
|
dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose + NADP+ <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + NADPH + H+
|
1.1.1.384
dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase
|
–
|
|
BRENDA:
BR51206
KEGG:
R05526
MetaCyc:
RXN-16262
|
|
|
|
15-hydroperoxyeicosatetraenoic_acid <=> 15H-11,12-EETA
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
KEGG:
R07042
|
|
|
|
n-butane + NADH + O2 + H+ <=> 1-butanol + NAD+ + H2O
|
1.14.13.230
butane monooxygenase (soluble)
|
–
|
|
BRENDA:
BR51806
KEGG:
R11448
MetaCyc:
RXN-17638
|
|
|
|
malonyl-CoA + (S)-methylmalonyl-CoA + NADPH + H+ + (2S)-ethylmalonyl-CoA <=> tylactone + CoA + CO2 + H2O + NADP+
|
2.3.1
|
–
|
|
KEGG:
R06448
MetaCyc:
RXN-15064
|
|
|
|
dimethyl_sulfone + 2 FMNH2 + 2 O2 <=> Methanesulfonic_acid + formaldehyde + 2 FMN + 2 H2O
|
1.14.14.35
dimethylsulfone monooxygenase
|
–
|
|
KEGG:
R10203
|
|
|
|
UDP-galactose + D-glucose <=> lactose + UDP + H+
|
2.4.1.22
lactose synthase
2.4.1.38
beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase
2.4.1.90
N-acetyllactosamine synthase
|
–
–
–
|
|
BRENDA:
BR44196
KEGG:
R00503;
R06067
MetaCyc:
LACTOSE-SYNTHASE-RXN
SABIO-RK:
9023
|
|
|
|
H+ + orotidine_5''-phosphate <=> CO2 + UMP
|
4.1.1.23
orotidine-5'-phosphate decarboxylase
|
–
|
|
BRENDA:
BR284
KEGG:
R00965
MetaCyc:
OROTPDECARB-RXN
SABIO-RK:
463
|
|
|
|
oxaloacetate + ATP <=> CO2 + phosphoenolpyruvate + ADP
|
4.1.1.31
phosphoenolpyruvate carboxylase
4.1.1.38
phosphoenolpyruvate carboxykinase (diphosphate)
4.1.1.49
phosphoenolpyruvate carboxykinase (ATP)
|
–
–
–
|
|
BRENDA:
BR308
KEGG:
R00341
MetaCyc:
PEPCARBOXYKIN-RXN
SABIO-RK:
151
|
|
|
|
pyruvate + L-serine <=> L-alanine + Hydroxypyruvate
|
2.6.1.44
alanine---glyoxylate transaminase
2.6.1.45
serine---glyoxylate transaminase
2.6.1.51
serine---pyruvate transaminase
2.6.1.64
glutamine---phenylpyruvate transaminase
2.6.1.B16
|
–
–
–
–
–
|
|
BRENDA:
BR47698
KEGG:
R00585
MetaCyc:
SERINE--PYRUVATE-AMINOTRANSFERASE-RXN
SABIO-RK:
985
|
|
|
|
malonyl-CoA + NADPH + H+ <=> 3-oxopropanoyl-CoA + NADP+ + H2O
|
not assigned
|
–
|
|
KEGG:
R00744
|
|
|
|
vindoline + Catharanthine <=> 3'',4''-Anhydrovinblastine
|
not assigned
|
–
|
|
KEGG:
R05858
|
|
|
|
succinate + NAD+ <=> fumarate + NADH + H+
|
1.3.1.6
fumarate reductase (NADH)
|
–
|
|
BRENDA:
BR36832
KEGG:
R00402
MetaCyc:
FUMARATE-REDUCTASE-NADH-RXN
|
|
|
|
paraxanthine + NADH + H+ + O2 <=> 1-Methylxanthine + NAD+ + formaldehyde + H2O
|
1.13.12
|
–
|
|
KEGG:
R07959
|
|
|
|
NADP+ + H2O + L-glutamate <=> NADPH + 2-oxoglutarate + NH3 + H+
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.2
glutamate dehydrogenase
1.4.1.3
glutamate dehydrogenase [NAD(P)+]
1.4.1.4
glutamate dehydrogenase (NADP+)
|
–
–
–
–
|
|
BRENDA:
BR36869;
BS397591-a
KEGG:
R00248
MetaCyc:
GLUTAMATE-DEHYDROGENASE-NADP+-RXN;
GLUTDEHYD-RXN;
RXN-20084
SABIO-RK:
757
|
|
|
|
Dialdehyde + H+ <=> 4,21-Dehydrocorynantheine_aldehyde + H2O
|
not assigned
|
–
|
|
KEGG:
R05845
|
|
|
|
dTDP-3-O-methyl-beta-L-rhamnose + Calicheamicin_PsAg <=> dTDP + Calicheamicin_alpha3(I)
|
2.4.1
|
–
|
|
KEGG:
R11423
|
|
|
|
prephenate + NAD+ <=> 4-hydroxyphenylpyruvate + CO2 + NADH
|
1.3.1.12
prephenate dehydrogenase
1.3.1.13
prephenate dehydrogenase (NADP+)
1.3.1.79
arogenate dehydrogenase [NAD(P)+]
|
–
–
–
|
|
BRENDA:
BR36797
KEGG:
R01728
MetaCyc:
PREPHENATEDEHYDROG-RXN
SABIO-RK:
1839
|
|
|
|
gamma-L-Glutamyl-L-propargylglycine + 2-oxoglutarate + O2 <=> L-gamma-Glutamyl-(3R)-L-beta-ethynylserine + succinate + CO2
|
1.14.11
|
–
|
|
KEGG:
R12411
|
|
|
|
L-lysine <=> (3R)-3-methyl-D-ornithine
|
5.4.99.58
methylornithine synthase
|
–
|
|
BRENDA:
BR50344
KEGG:
R10010
MetaCyc:
RXN-13074
|
|
|
|
H+ + methylglyoxal + NADH <=> Hydroxyacetone + NAD+
|
1.1.1
1.1.1.1
alcohol dehydrogenase
1.1.1.21
aldose reductase
1.1.1.75
(R)-aminopropanol dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BS188635
KEGG:
R10718
MetaCyc:
RXN0-5213
SABIO-RK:
9806
|
|
|
|
(R)-2-methylmalonyl-CoA <=> succinyl-CoA
|
5.4.99.2
methylmalonyl-CoA mutase
5.4.99.63
ethylmalonyl-CoA mutase
5.4.99.64
2-hydroxyisobutanoyl-CoA mutase
|
–
–
–
|
|
BRENDA:
BR249;
BS380077;
BS390473
KEGG:
R00833
MetaCyc:
METHYLMALONYL-COA-MUT-RXN
SABIO-RK:
10453;
1174
|
|
|
|
UDP-beta-L-arabinopyranose <=> UDP-D-xylose
|
5.1.3.2
UDP-glucose 4-epimerase
5.1.3.5
UDP-arabinose 4-epimerase
|
–
–
|
|
BRENDA:
BR199
KEGG:
R01473
MetaCyc:
UDP-ARABINOSE-4-EPIMERASE-RXN
SABIO-RK:
8675
|
|
|
|
3-Dehydro-scyllo-inosose + H2O <=> 5-Dehydro-L-gluconate + H+
|
3.7.1
|
–
|
|
KEGG:
R11771
MetaCyc:
RXN-14359
|
|
|
|
thiamine_diphosphate + phosphate + H+ <=> thiamine_triphosphate + H2O + H+
|
3.6.1.28
thiamine-triphosphatase
|
–
|
|
BRENDA:
BR22768
KEGG:
R00618
MetaCyc:
RXN0-7041;
THIAMIN-TRIPHOSPHATASE-RXN
SABIO-RK:
1008
|
|
|
|
Betaine_aldehyde + O2 + H2O <=> betaine + H2O2 + H+
|
1.1.3.17
choline oxidase
1.1.99.1
choline dehydrogenase
|
–
–
|
|
BRENDA:
BR48842
KEGG:
R08211
MetaCyc:
CHOLINE-OXIDASEII-RXN
SABIO-RK:
7263
|
|
|
|
N1-methylnicotinamide + O2 + H2O <=> N1-methyl-4-pyridone-3-carboxamide + H2O2 + H+
|
1.2.3.1
aldehyde oxidase
|
–
|
|
KEGG:
R04085
|
|
|
|
H+ + UDP-D-galacturonate <=> UDP-beta-L-arabinopyranose + CO2
|
4.1.1.67
UDP-galacturonate decarboxylase
|
–
|
|
BRENDA:
BR328
KEGG:
R02636
MetaCyc:
UDP-GALACTURONATE-DECARBOXYLASE-RXN
|
|
|
|
chorismate + NH3 <=> anthranilate + pyruvate + H2O
|
4.1.3.27
anthranilate synthase
|
–
|
|
BRENDA:
BS380574
KEGG:
R00985
SABIO-RK:
1279
|
|
|
|
cyanide + 2 H2O <=> NH3 + formate
|
3.5.5
|
–
|
|
KEGG:
R00152
|
|
|
|
3-phosphoshikimate + phosphoenolpyruvate <=> 5-enolpyruvylshikimate_3-phosphate + phosphate
|
2.5.1.19
3-phosphoshikimate 1-carboxyvinyltransferase
|
–
|
|
BRENDA:
BR47516
KEGG:
R03460
MetaCyc:
2.5.1.19-RXN
SABIO-RK:
3254
|
|
|
|
2-Pyrone-4,6-dicarboxylate + H2O <=> 4-oxalomesaconate + H+
|
3.1.1.57
2-pyrone-4,6-dicarboxylate lactonase
|
–
|
|
BRENDA:
BR47925
KEGG:
R04277
MetaCyc:
RXN-2462
|
|
|
|
trans-2-decenoyl-CoA + NADPH <=> decanoyl-CoA + NADP+
|
1.3.1.38
trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BS258527
KEGG:
R04753
SABIO-RK:
4409
|
|
|
|
spermidine + glutathione + ATP <=> H+ + glutathionylspermidine + ADP + phosphate
|
6.3.1.8
glutathionylspermidine synthase
6.3.1.9
trypanothione synthase
|
–
–
|
|
BRENDA:
BR99
KEGG:
R01917
MetaCyc:
GSPSYN-RXN
SABIO-RK:
1971
|
|
|
|
(S,S)-Tartrate <=> H2O + oxaloacetate
|
4.2.1.2
fumarate hydratase
4.2.1.32
L(+)-tartrate dehydratase
4.2.1.34
(S)-2-methylmalate dehydratase
4.2.1.81
D(-)-tartrate dehydratase
|
–
–
–
–
|
|
BRENDA:
BR412;
BR48327
KEGG:
R00339;
R00340
MetaCyc:
D--TARTRATE-DEHYDRATASE-RXN;
LTARTDEHYDRA-RXN
SABIO-RK:
820
|
|
|
|
pyruvate + dATP <=> phosphoenolpyruvate + dADP + H+
|
2.7.1.40
pyruvate kinase
|
–
|
|
BRENDA:
BS411968
KEGG:
R01138
MetaCyc:
RXN-14192
SABIO-RK:
57
|
|
|
|
25-hydroxyvitamin_D3 + reduced_adrenodoxin + H+ + O2 <=> secalciferol + oxidized_ferredoxin + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
|
BRENDA:
BR49598
KEGG:
R09516
MetaCyc:
RXN-12069
|
|
|
|
Avermectin_B1a_aglycone + S-adenosyl-L-methionine <=> Avermectin_A1a_aglycone + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R06477
|
|
|
|
O-phospho-L-homoserine + H2O <=> phosphate + L-threonine
|
4.2.3.1
threonine synthase
|
–
|
|
BRENDA:
BR16083
KEGG:
R01466
MetaCyc:
THRESYN-RXN
SABIO-RK:
1642
|
|
|
|
codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + CO2
|
1.14.11.32
codeine 3-O-demethylase
|
–
|
|
BRENDA:
BR49146
KEGG:
R09402
MetaCyc:
RXN-8152
|
|
|
|
beta-Alanine + 2-oxoglutarate <=> malonate_semialdehyde + L-glutamate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.22
(S)-3-amino-2-methylpropionate transaminase
2.6.1.55
taurine---2-oxoglutarate transaminase
2.6.1.ak
|
–
–
–
–
–
|
|
BRENDA:
BS353590
KEGG:
R00908
MetaCyc:
RXN-2901
SABIO-RK:
1228
|
|
|
|
L-asparagine + a_2-oxo_carboxylate <=> 2-oxosuccinamic_acid + an_L-amino_acid
|
2.6.1.14
asparagine---oxo-acid transaminase
|
–
|
|
KEGG:
R01346
|
|
|
|
L-pyrroline-5-carboxylate + NAD+ + H2O <=> H+ + L-glutamate + NADH
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
|
–
–
|
|
BRENDA:
BS259182
KEGG:
R00707
MetaCyc:
PYRROLINECARBDEHYDROG-RXN
SABIO-RK:
1083;
15086
|
|
|
|
episterol + O2 + ferricytochrome_b5 + H+ <=> 5-dehydroepisterol + H2O + ferricytochrome_b5
|
1.14.19.20
Delta7-sterol 5(6)-desaturase
|
–
|
|
BRENDA:
BS428606
KEGG:
R07491;
R07505
MetaCyc:
RXN3O-218
|
|
|
|
GDP-L-fucose + beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->3)-[alpha-L-Fuc-(1->2)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer <=> GDP + Type_IIIH_glycolipid
|
2.4.1.69
type 1 galactoside alpha-(1,2)-fucosyltransferase
|
–
|
|
KEGG:
R06031
|
|
|
|
Cathasterone + O2 + reduced_acceptor <=> Teasterone + H2O + acceptor
|
1.14
|
–
|
|
KEGG:
R07431
|
|
|
|
(R)-citramalate <=> citraconate + H2O
|
4.2.1.31
maleate hydratase
4.2.1.35
(R)-2-methylmalate dehydratase
|
–
–
|
|
BRENDA:
BR415
KEGG:
R03896
MetaCyc:
R-2-METHYLMALATE-DEHYDRATASE-RXN
SABIO-RK:
3641
|
|
|
|
H+ + acetyl_phosphate + sulfite <=> 2-sulfoacetaldehyde + phosphate
|
2.3.3.15
sulfoacetaldehyde acetyltransferase
|
–
|
|
BRENDA:
BR47451
KEGG:
R05651
MetaCyc:
RXN-2364
|
|
|
|
7,9,9''-tricis-neurosporene + a_quinone <=> 7,9,7'',9''-tetracis-lycopene + a_quinol
|
1.3.5.6
9,9'-dicis-zeta-carotene desaturase
|
–
|
|
BRENDA:
BR49639
KEGG:
R09658
|
|
|
|
maltose <=> trehalose
|
5.4.99.16
maltose alpha-D-glucosyltransferase
|
–
|
|
BRENDA:
BR248
KEGG:
R01557;
R06218
MetaCyc:
5.4.99.16-RXN
|
|
|
|
ascorbate + H2O2 <=> dehydroascorbate + H2O
|
1.11.1.11
L-ascorbate peroxidase
1.11.1.5
cytochrome-c peroxidase
1.11.1.7
peroxidase
|
–
–
–
|
|
BRENDA:
BS260337
KEGG:
R00644
SABIO-RK:
1027;
1029
|
|
|
|
CO + H2O + oxidized_ferredoxin <=> CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.2.7.4
anaerobic carbon monoxide dehydrogenase
|
–
|
|
BRENDA:
BR36793
KEGG:
R07157
MetaCyc:
1.2.7.4-RXN
|
|
|
|
fatty_acid + CoA + ATP <=> stearoyl-CoA + AMP + diphosphate
|
1.13.12.7
firefly luciferase
6.2.1.12
4-coumarate---CoA ligase
6.2.1.3
long-chain-fatty-acid---CoA ligase
6.2.1.30
phenylacetate---CoA ligase
6.2.1.B3
|
–
–
–
–
–
|
|
BRENDA:
BR82;
BS287
KEGG:
R00390;
R01280
MetaCyc:
RXN-16380;
RXN-7904;
RXN-9623
SABIO-RK:
10953;
1496
|
|
|
|
CTP + D-tagatose_6-phosphate <=> CDP + D-tagatose_1,6-bisphosphate
|
2.7.1.11
6-phosphofructokinase
2.7.1.144
tagatose-6-phosphate kinase
|
–
–
|
|
BRENDA:
BS357293
KEGG:
R03237
|
|
|
|
oxaloacetate + acetyl-CoA + phosphate + ADP <=> citrate + CoA + ATP
|
2.3.3.8
ATP citrate synthase
|
–
|
|
BRENDA:
BR44130
KEGG:
R00352
MetaCyc:
ATP-CITRATE-PRO-S--LYASE-RXN
SABIO-RK:
266
|
|
|
|
dichlorochromopyrrolate + O2 + NADH + H+ <=> dichloroarcyriaflavin_A + CO2 + H2O + NAD+
|
1.13.12.17
dichloroarcyriaflavin A synthase
|
–
|
|
BRENDA:
BR49133
KEGG:
R09567
MetaCyc:
RXN-10845
|
|
|
|
Indole-3-acetamide <=> indole-3-acetonitrile + H2O
|
4.2.1.84
nitrile hydratase
|
–
|
|
BRENDA:
BS363352
KEGG:
R04020
MetaCyc:
RXN-7567
|
|
|
|
beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + H2O <=> beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + sulfate
|
3.1.6.14
N-acetylglucosamine-6-sulfatase
|
–
|
|
KEGG:
R07808
|
|
|
|
behenoyl-CoA + malonyl-CoA <=> a_very-long-chain_3-oxoacyl-CoA + CO2 + CoA
|
2.3.1.199
very-long-chain 3-oxoacyl-CoA synthase
|
–
|
|
BRENDA:
BR50172
KEGG:
R10825
|
|
|
|
dTDP-3-amino-2,3,6-trideoxy-4-keto-D-glucose + 2-oxoglutarate <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + L-glutamate
|
2.6.1
|
–
|
|
KEGG:
R06631
MetaCyc:
RXN-15233
|
|
|
|
OPC8-CoA + FAD <=> trans-2-Enoyl-OPC8-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
|
KEGG:
R07888
|
|
|
|
acetate + diphosphate <=> phosphate + acetyl_phosphate
|
2.7.2.12
acetate kinase (diphosphate)
|
–
|
|
BRENDA:
BR47822
KEGG:
R00320
MetaCyc:
ACETATE-KINASE-PYROPHOSPHATE-RXN
|
|
|
|
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate <=> 7,8-dihydroneopterin_3''-phosphate + H2O
|
4.2.1.160
2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase
|
–
|
|
BRENDA:
BR51538
KEGG:
R11072
MetaCyc:
RXN-15730
|
|
|
|
4-aminobutanoate + pyruvate <=> succinate_semialdehyde + L-alanine
|
2.6.1.116
6-aminohexanoate aminotransferase
2.6.1.18
beta-alanine---pyruvate transaminase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.40
(R)-3-amino-2-methylpropionate---pyruvate transaminase
2.6.1.96
4-aminobutyrate---pyruvate transaminase
|
–
–
–
–
–
|
|
BRENDA:
BR50304
KEGG:
R10178
MetaCyc:
RXN-6902
|
|
|
|
(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O <=> Salicylaldehyde + pyruvate
|
4.1.2.45
trans-o-hydroxybenzylidenepyruvate hydratase-aldolase
|
–
|
|
BRENDA:
BR49207
KEGG:
R05136
MetaCyc:
RXN-8615
|
|
|
|
butyryl-[acyl-carrier_protein] + NAD+ <=> trans-but-2-enoyl-[acyl-carrier_protein] + NADH + H+
|
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1
|
–
–
|
|
BRENDA:
BS374746
KEGG:
R04429
MetaCyc:
RXN-9657
SABIO-RK:
4116
|
|
|
|
(S)-ureidoglycolate <=> Urea + glyoxylate
|
3.5.3.21
methylenediurea deaminase
3.5.3.4
allantoicase
4.3.2.3
ureidoglycolate lyase
|
–
–
–
|
|
BRENDA:
BR3433;
BS17938
KEGG:
R00776
MetaCyc:
UREIDOGLYCOLATE-LYASE-RXN
SABIO-RK:
12069;
286
|
|
|
|
alpha-D-glucose_1-phosphate <=> alpha-D-glucose_6-phosphate
|
5.4.2.10
phosphoglucosamine mutase
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3
phosphoacetylglucosamine mutase
5.4.2.5
phosphoglucomutase (glucose-cofactor)
5.4.2.6
beta-phosphoglucomutase
5.4.2.8
phosphomannomutase
|
–
–
–
–
–
–
|
|
BRENDA:
BS1161
KEGG:
R00959
SABIO-RK:
11;
9261
|
|
|
|
3-oxoadipate + NADP+ <=> maleylacetate + NADPH + H+
|
1.3.1.32
maleylacetate reductase
|
–
|
|
BRENDA:
BR36814
KEGG:
R02989
MetaCyc:
MALEYLACETATE-REDUCTASE-RXN
|
|
|
|
N-succinyl-L-glutamate_5-semialdehyde + NAD+ + H2O <=> N2-succinylglutamate + NADH + H+
|
1.2.1.71
succinylglutamate-semialdehyde dehydrogenase
|
–
|
|
BRENDA:
BR48653
KEGG:
R05049
MetaCyc:
SUCCGLUALDDEHYD-RXN
|
|
|
|
S-adenosyl-L-methionine + nocardicin_G <=> isonocardicin_C + S-methyl-5''-thioadenosine + H+
|
2.5.1.38
isonocardicin synthase
|
–
|
|
BRENDA:
BR44284
KEGG:
R10881
MetaCyc:
RXN-17837
|
|
|
|
LysW-L-glutamyl_5-phosphate + NADPH + H+ <=> LysW-L-glutamate_5-semialdehyde + NADP+ + phosphate
|
1.2.1
|
–
|
|
KEGG:
R10931
|
|
|
|
cis-trans-nepetalactol + reduced_flavodoxin + O2 <=> 7-deoxyloganetic_alcohol + flavin + H2O
|
1.14.14.161
nepetalactol monooxygenase
|
–
|
|
BRENDA:
BR52520
KEGG:
R12231
|
|
|
|
L-methionine + H2O <=> methanethiol + 2-oxobutyrate + NH3
|
4.4.1.11
methionine gamma-lyase
|
–
|
|
BRENDA:
BR3437
KEGG:
R00654
MetaCyc:
METHIONINE-GAMMA-LYASE-RXN
SABIO-RK:
1038
|
|
|
|
(R)-2,3-dihydroxy-3-methylbutanoate + NADP+ <=> 3-hydroxy-3-methyl-2-oxobutanoic_acid + NADPH + H+
|
1.1.1.86
ketol-acid reductoisomerase (NADP+)
|
–
|
|
KEGG:
R04440
SABIO-RK:
8850
|
|
|
|
phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O <=> phosphate + N-acetylneuraminate
|
2.5.1.56
N-acetylneuraminate synthase
|
–
|
|
BRENDA:
BR47462
KEGG:
R01804
SABIO-RK:
1890
|
|
|
|
5beta-Pregnan-3alpha-ol-20-one + NADH + H+ <=> 5beta-pregnane-3alpha,20alpha-diol + NAD+
|
1.1.1.112
indanol dehydrogenase
1.1.1.149
20alpha-hydroxysteroid dehydrogenase
1.1.1.53
3alpha(or 20beta)-hydroxysteroid dehydrogenase
|
–
–
–
|
|
BRENDA:
BS187023-a
KEGG:
R04847
|
|
|
|
ADP + H2O <=> H+ + AMP + phosphate
|
3.1.15.1
venom exonuclease
3.1.3.1
alkaline phosphatase
3.1.3.10
glucose-1-phosphatase
3.1.3.2
acid phosphatase
3.1.3.26
4-phytase
3.1.3.31
nucleotidase
3.1.3.49
[pyruvate kinase]-phosphatase
3.1.3.5
5'-nucleotidase
3.1.3.8
3-phytase
3.1.4.1
phosphodiesterase I
3.1.4.12
sphingomyelin phosphodiesterase
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.1.4.37
2',3'-cyclic-nucleotide 3'-phosphodiesterase
3.6.1.1
inorganic diphosphatase
3.6.1.11
exopolyphosphatase
3.6.1.13
ADP-ribose diphosphatase
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.18
FAD diphosphatase
3.6.1.22
NAD+ diphosphatase
3.6.1.42
guanosine-diphosphatase
3.6.1.5
apyrase
3.6.1.53
Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase
3.6.1.56
2-hydroxy-dATP diphosphatase
3.6.1.6
nucleoside diphosphate phosphatase
3.6.1.62
5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase
3.6.1.64
inosine diphosphate phosphatase
3.6.1.9
nucleotide diphosphatase
6.1.1.14
glycine---tRNA ligase
7.6.2.9
ABC-type quaternary amine transporter
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS391186
KEGG:
R00122
MetaCyc:
RXN-10862
SABIO-RK:
246
|
|
|
|
O2 + L-cysteine <=> H+ + L-cysteine_sulfinic_acid
|
1.13.11.20
cysteine dioxygenase
1.14.99.52
L-cysteinyl-L-histidinylsulfoxide synthase
|
–
–
|
|
BRENDA:
BR40484
KEGG:
R00893
MetaCyc:
CYSTEINE-DIOXYGENASE-RXN
SABIO-RK:
1216;
14729
|
|
|
|
(22S,24R)-22-hydroxy-5alpha-ergostan-3-one + NADP+ <=> H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH
|
1.3.1
1.3.1.22
3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
|
–
–
|
|
KEGG:
R07447
MetaCyc:
RXN-4229
|
|
|
|
L-tyrosine + O2 <=> L-Dopa
|
1.10.3.1
catechol oxidase
1.14.18.1
tyrosinase
|
–
–
|
|
BRENDA:
BR50166
KEGG:
R00031;
R00731
MetaCyc:
RXN-5861
SABIO-RK:
1094;
622
|
|
|
|
3-Methylxanthine + NADH + O2 + H+ <=> xanthine + NAD+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
|
–
–
|
|
BRENDA:
BR50581-a
KEGG:
R07967
MetaCyc:
RXN-13109_WOP
|
|
|
|
propionyl-CoA + NADP+ <=> acryloyl-CoA + NADPH + H+
|
1.3.1
1.3.1.84
acrylyl-CoA reductase (NADPH)
1.3.1.95
acrylyl-CoA reductase (NADH)
|
–
–
–
|
|
BRENDA:
BR49115
KEGG:
R00919
MetaCyc:
RXN-9087
SABIO-RK:
1239
|
|
|
|
UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-galactosaminyl-R <=> UDP + beta-D-GlcNAc-(1->6)-alpha-D-GalNAc-1-Ser/Thr
|
2.4.1.102
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
2.4.1.148
acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
|
–
–
|
|
KEGG:
R05910
|
|
|
|
acetyl-CoA + propionate <=> acetate + propionyl-CoA
|
2.8.3.1
propionate CoA-transferase
2.8.3.12
glutaconate CoA-transferase
2.8.3.14
5-hydroxypentanoate CoA-transferase
2.8.3.18
succinyl-CoA:acetate CoA-transferase
|
–
–
–
–
|
|
BRENDA:
BR48124
KEGG:
R00928
MetaCyc:
PROPIONATE-COA-TRANSFERASE-RXN
SABIO-RK:
170
|
|
|
|
acetyl-CoA + pyruvate + H2O <=> H+ + (R)-citramalate + CoA
|
2.3.1.182
(R)-citramalate synthase
2.3.3.13
2-isopropylmalate synthase
|
–
–
|
|
BRENDA:
BR48833
KEGG:
R07399
MetaCyc:
RXN-7743
SABIO-RK:
9043
|
|
|
|
L-Histidinol_phosphate + 2-oxoglutarate <=> 3-(Imidazol-4-yl)-2-oxopropyl_phosphate + L-glutamate
|
2.6.1.9
histidinol-phosphate transaminase
|
–
|
|
BRENDA:
BR47443
KEGG:
R03243
MetaCyc:
HISTAMINOTRANS-RXN
SABIO-RK:
3064
|
|
|
|
2-Hydroxy-6-oxoocta-2,4,7-trienoate + H2O <=> 2-hydroxy-2,4-pentadienoate + Acrylate
|
3.7.1.9
2-hydroxymuconate-6-semialdehyde hydrolase
|
–
|
|
KEGG:
R05362
|
|
|
|
trans-5-O-caffeoylshikimate + CoA <=> caffeoyl-CoA + shikimate
|
2.3.1
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
2.3.1.99
quinate O-hydroxycinnamoyltransferase
|
–
–
–
|
|
BRENDA:
BS320440
KEGG:
R07433
MetaCyc:
RXN-2621
|
|
|
|
p-coumaric_acid <=> caffeic_acid
|
1.14.13
|
–
|
|
KEGG:
R07826
|
|
|
|
UDP-glucose + H2O <=> UMP + alpha-D-aldose_1-phosphate + H+
|
3.1.4.1
phosphodiesterase I
3.6.1.45
UDP-sugar diphosphatase
3.6.1.8
ATP diphosphatase
3.6.1.9
nucleotide diphosphatase
|
–
–
–
–
|
|
BRENDA:
BR3333;
BS139792;
BS402967
KEGG:
R00287;
R03986
MetaCyc:
UDPSUGARHYDRO-RXN
SABIO-RK:
446
|
|
|
|
cyclohex-1-ene-1-carbonyl-CoA + H2O <=> 2-hydroxycyclohexane-1-carbonyl-CoA
|
4.2.1
4.2.1.100
cyclohexa-1,5-dienecarbonyl-CoA hydratase
|
–
–
|
|
BRENDA:
BS186637
KEGG:
R05600
MetaCyc:
R266-RXN
|
|
|
|
L-dihydroanticapsin + NAD+ <=> anticapsin + NADH + H+
|
1.1.1.385
dihydroanticapsin dehydrogenase
|
–
|
|
BRENDA:
BR51207
KEGG:
R10917
MetaCyc:
RXN-16285
|
|
|
|
pseudouridine + ATP <=> H+ + pseudouridine_5''-phosphate + ADP
|
2.7.1.83
pseudouridine kinase
|
–
|
|
BRENDA:
BR47387
KEGG:
R03315
MetaCyc:
PSEUDOURIDINE-KINASE-RXN
|
|
|
|
glycine + protein + NAD+ <=> ADP-5-ethyl-4-methylthiazole-2-carboxylate + nicotinamide + [Protein]-dehydroalanine + H2O + H+
|
2.4.2.60
cysteine-dependent adenosine diphosphate thiazole synthase
|
–
|
|
KEGG:
R10685
MetaCyc:
RXNQT-4300
|
|
|
|
ethanol + 2 ferricytochrome_c <=> acetaldehyde + 2 ferricytochrome_c
|
1.1.2.8
alcohol dehydrogenase (cytochrome c)
1.1.2.9
1-butanol dehydrogenase (cytochrome c)
|
–
–
|
|
BRENDA:
BS424803
KEGG:
R05198
|
|
|
|
phenol + O2 + NADH + H+ <=> catechol + H2O + NAD+
|
1.14.13.244
phenol 2-monooxygenase (NADH)
1.14.13.7
phenol 2-monooxygenase (NADPH)
1.14.14.20
phenol 2-monooxygenase (FADH2)
|
–
–
–
|
|
BRENDA:
BR52671
KEGG:
R10043
MetaCyc:
RXN-17503
|
|
|
|
cobalt-factor_III <=> cobalt-precorrin-3B
|
not assigned
|
–
|
|
KEGG:
R08716
|
|
|
|
7-hydroxymethylchlorophyll_a + NAD+ <=> chlorophyll_b + NADH
|
1.1.1.294
chlorophyll(ide) b reductase
|
–
|
|
KEGG:
R09069
MetaCyc:
RXN-7678_WOP
|
|
|
|
acetaldehyde + NADP+ + H2O <=> acetate + NADPH + H+
|
1.2.1
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.4
aldehyde dehydrogenase (NADP+)
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.8
betaine-aldehyde dehydrogenase
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS231682
KEGG:
R00711
MetaCyc:
RXN0-3962
SABIO-RK:
541
|
|
|
|
H+ + H2O + cytidine <=> uridine + NH3
|
3.5.4.5
cytidine deaminase
|
–
|
|
BRENDA:
BR22742
KEGG:
R01878
MetaCyc:
CYTIDEAM2-RXN
SABIO-RK:
89
|
|
|
|
squalene + reduced_flavodoxin + O2 <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + flavin + H2O
|
1.14.14.17
squalene monooxygenase
|
–
|
|
BRENDA:
BR40381
KEGG:
R02874
|
|
|
|
coenzyme_B + coenzyme_M + methanophenazine <=> CoM-S-S-CoB + dihydromethanophenazine
|
1.8.98.1
dihydromethanophenazine:CoB-CoM heterodisulfide reductase
|
–
|
|
BRENDA:
BR47628
KEGG:
R04540
MetaCyc:
1.8.98.1-RXN
|
|
|
|
trans-aconitate <=> cis-aconitate
|
5.3.3.7
aconitate Delta-isomerase
|
–
|
|
BRENDA:
BR5
KEGG:
R02244
MetaCyc:
ACONITATE-DELTA-ISOMERASE-RXN
SABIO-RK:
2214
|
|
|
|
(S)-3-hydroxybutyryl-CoA + NADP+ <=> acetoacetyl-CoA + NADPH + H+
|
1.1.1.157
3-hydroxybutyryl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
BRENDA:
BR29222;
BS429714
KEGG:
R01976
MetaCyc:
3-HYDROXYBUTYRYL-COA-DEHYDROGENASE-RXN
SABIO-RK:
2019
|
|
|
|
neoxanthin <=> 9''-cis-neoxanthin
|
5.2.1
|
–
|
|
KEGG:
R06949
MetaCyc:
RXN-8074
|
|
|
|
6-deoxocathasterone + O2 <=> 6-deoxoteasterone + H2O
|
1.14
|
–
|
|
KEGG:
R07448
|
|
|
|
putrescine + S-adenosylmethioninamine <=> H+ + spermidine + S-methyl-5''-thioadenosine
|
2.5.1.104
N1-aminopropylagmatine synthase
2.5.1.16
spermidine synthase
2.5.1.23
sym-norspermidine synthase
|
–
–
–
|
|
BRENDA:
BR47664
KEGG:
R01920
MetaCyc:
SPERMIDINESYN-RXN
SABIO-RK:
1974
|
|
|
|
S-adenosyl-L-methionine + putrescine <=> H+ + S-adenosyl-L-homocysteine + N-methylputrescine
|
2.1.1.53
putrescine N-methyltransferase
|
–
|
|
BRENDA:
BR43902
KEGG:
R01153
MetaCyc:
PUTRESCINE-N-METHYLTRANSFERASE-RXN
SABIO-RK:
1394
|
|
|
|
L-threonine <=> glycine + acetaldehyde
|
4.1.2.26
phenylserine aldolase
4.1.2.42
D-threonine aldolase
4.1.2.48
low-specificity L-threonine aldolase
4.1.2.5
L-threonine aldolase
|
–
–
–
–
|
|
BRENDA:
BR373;
BR48467
KEGG:
R00751;
R08195;
R08196
MetaCyc:
4.1.2.42-RXN;
RXN-9702;
THREONINE-ALDOLASE-RXN
SABIO-RK:
1110
|
|
|
|
geranylgeranyl_diphosphate <=> diphosphate + taxa-4,11-diene
|
4.2.3.17
taxadiene synthase
|
–
|
|
BRENDA:
BR44341
KEGG:
R06305
MetaCyc:
4.2.3.17-RXN
|
|
|
|
N2-succinylglutamate + H2O <=> L-glutamate + succinate
|
3.5.1.96
succinylglutamate desuccinylase
|
–
|
|
BRENDA:
BR48702
KEGG:
R00411
MetaCyc:
SUCCGLUDESUCC-RXN
|
|
|
|
S-adenosyl-L-methionine + 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil <=> coenzyme_F0 + 5''-deoxyadenosine + L-methionine + NH3 + H+
|
4.3.1.32
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase
|
–
|
|
BRENDA:
BR52491
KEGG:
R12162
MetaCyc:
RXN-19230
|
|
|
|
Chloroacetaldehyde + H2O + NAD+ <=> H+ + Chloroacetate + NADH
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.4
aldehyde dehydrogenase (NADP+)
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.69
fluoroacetaldehyde dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BS231504
KEGG:
R05286
MetaCyc:
ALDXANAU-RXN
SABIO-RK:
4895
|
|
|
|
D-glutamine + H2O <=> NH3 + D-glutamate
|
3.5.1.2
glutaminase
3.5.1.35
D-glutaminase
3.5.1.38
glutamin-(asparagin-)ase
|
–
–
–
|
|
BRENDA:
BR22687
KEGG:
R01579
MetaCyc:
D-GLUTAMINASE-RXN
|
|
|
|
acetyl-CoA + oxaloacetate <=> malonyl-CoA + pyruvate
|
2.1.3.1
methylmalonyl-CoA carboxytransferase
|
–
|
|
BRENDA:
BS320094
KEGG:
R00353
|
|
|
|
2,3-bisphospho-D-glycerate + protein_L-histidine <=> 3-phospho-D-glycerate + protein_Ntau-phospho-L-histidine
|
5.4.2.11
phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
|
–
|
|
KEGG:
R01516
|
|
|
|
tryptamine + secologanin <=> strictosidine + H2O
|
4.3.3.2
strictosidine synthase
|
–
|
|
BRENDA:
BR48360
KEGG:
R03738
MetaCyc:
STRICTOSIDINE-SYNTHASE-RXN
|
|
|
|
XMP + diphosphate <=> xanthine + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.22
xanthine phosphoribosyltransferase
2.4.2.7
adenine phosphoribosyltransferase
2.4.2.8
hypoxanthine phosphoribosyltransferase
|
–
–
–
|
|
BRENDA:
BR47505
KEGG:
R02142
MetaCyc:
XANPRIBOSYLTRAN-RXN
SABIO-RK:
194
|
|
|
|
propionyl-CoA + O2 <=> acryloyl-CoA + H2O2
|
1.3.3.6
acyl-CoA oxidase
|
–
|
|
KEGG:
R12356
MetaCyc:
RXN-15977
|
|
|
|
L-lactaldehyde + NADP+ <=> methylglyoxal + NADPH + H+
|
1.1.1.156
glycerol 2-dehydrogenase (NADP+)
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.283
methylglyoxal reductase (NADPH)
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
1.1.1.72
glycerol dehydrogenase (NADP+)
1.1.1.78
methylglyoxal reductase (NADH)
1.2.1.49
2-oxoaldehyde dehydrogenase (NADP+)
|
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR48480;
BS139557
KEGG:
R02260
MetaCyc:
1.1.1.283-RXN
SABIO-RK:
550;
9214
|
|
|
|
N-acetylneuraminate_9-phosphate + H2O <=> N-acetylneuraminate + phosphate
|
3.1.3.103
3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphatase
3.1.3.29
N-acylneuraminate-9-phosphatase
|
–
–
|
|
BRENDA:
BS437718
KEGG:
R01805
SABIO-RK:
1891
|
|
|
|
H2O + CTP <=> H+ + phosphate + CDP
|
3.1.3.2
acid phosphatase
3.1.3.31
nucleotidase
3.1.3.5
5'-nucleotidase
3.1.3.8
3-phytase
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
3.1.4.37
2',3'-cyclic-nucleotide 3'-phosphodiesterase
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.28
thiamine-triphosphatase
3.6.1.3
adenosinetriphosphatase
3.6.1.5
apyrase
3.6.1.6
nucleoside diphosphate phosphatase
3.6.1.9
nucleotide diphosphatase
3.6.1.B17
3.6.4.12
DNA helicase
3.6.4.13
RNA helicase
3.6.4.B10
3.6.4.B6
5.6.1.5
proteasome ATPase
7.1.2.2
H+-transporting two-sector ATPase
7.6.2.2
ABC-type xenobiotic transporter
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS141413
KEGG:
R00569
MetaCyc:
RXN-12195
SABIO-RK:
209
|
|
|
|
torulene + O2 <=> 4''-apo-beta-carotenal + 3-methylbut-2-enal
|
1.13.11.59
torulene dioxygenase
1.13.11.67
8'-apo-beta-carotenoid 14',13'-cleaving dioxygenase
|
–
–
|
|
BRENDA:
BR49798
KEGG:
R09782
MetaCyc:
RXN-11989
|
|
|
|
4''-apo-beta-carotenal + NAD+ + H2O <=> beta-apo-4'-carotenoic_acid + NADH + H+
|
1.2.1.82
beta-apo-4'-carotenal oxygenase
|
–
|
|
BRENDA:
BR49795
KEGG:
R09783
MetaCyc:
RXN-11998
|
|
|
|
4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD+ <=> cycloeucalenone + NADH + CO2
|
1.1.1.418
plant 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
|
–
|
|
BRENDA:
BS446830
KEGG:
R12371
MetaCyc:
RXN-11928
|
|
|
|
alpha-Aminoadipoyl-S-acyl_enzyme + NADPH + H+ <=> (S)-2-amino-6-oxohexanoate + Holo-Lys2 + NADP+
|
1.2.1.95
L-2-aminoadipate reductase
|
–
|
|
KEGG:
R04390
|
|
|
|
L-cystine + glutathione <=> GSSG + L-cysteine
|
1.8.1.6
cystine reductase
1.8.4.4
glutathione---cystine transhydrogenase
1.8.4.9
adenylyl-sulfate reductase (glutathione)
|
–
–
–
|
|
BRENDA:
BR37026
KEGG:
R01109;
R01113
MetaCyc:
1.8.4.4-RXN
|
|
|
|
(5-hydroxy-1H-indol-3-yl)acetaldehyde + NAD+ + H2O <=> 5-hydroxyindoleacetate + NADH + H+
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
|
–
–
|
|
BRENDA:
BS231592
KEGG:
R04903
MetaCyc:
RXN-10780
SABIO-RK:
4543
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->6)-alpha-D-Man2P(EtN)-(1->4)-alpha-D-GlcN-(1->6)-Ino(acyl)-P <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-alpha-D-Man2P(EtN)-(1->4)-alpha-D-GlcN-(1->6)-Ino(acyl)-P
|
2.4.1
|
–
|
|
KEGG:
R05922
|
|
|
|
(2R)-3-sulfolactate + NADP+ <=> 3-sulfopyruvate + NADPH + H+
|
1.1.1.338
(2R)-3-sulfolactate dehydrogenase (NADP+)
1.1.1.375
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
|
–
–
|
|
BRENDA:
BR50231
KEGG:
R07137
MetaCyc:
RXN-11690;
RXN-15670
|
|
|
|
propionate + ATP <=> propanoyl_phosphate + ADP
|
2.7.2.1
acetate kinase
2.7.2.14
branched-chain-fatty-acid kinase
2.7.2.15
propionate kinase
2.7.2.6
formate kinase
2.7.2.7
butyrate kinase
|
–
–
–
–
–
|
|
BRENDA:
BR48584
KEGG:
R01353
MetaCyc:
PROPKIN-RXN
SABIO-RK:
1558
|
|
|
|
4-methyl-2-oxopentanoate + CoA + oxidized_ferredoxin <=> isovaleryl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
1.2.7.8
indolepyruvate ferredoxin oxidoreductase
|
–
–
|
|
BRENDA:
BS359415
KEGG:
R08566
MetaCyc:
RXN-19534
|
|
|
|
4-hydroxybenzoyl-CoA + H2O <=> H+ + 4-hydroxybenzoate + CoA
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.23
4-hydroxybenzoyl-CoA thioesterase
|
–
–
–
|
|
BRENDA:
BR2508
KEGG:
R01301
MetaCyc:
3.1.2.23-RXN
SABIO-RK:
1516
|
|
|
|
2-dehydro-3-deoxy-D-gluconate + ATP <=> H+ + 2-keto-3-deoxy_phosphogluconate + ADP
|
2.7.1.178
2-dehydro-3-deoxyglucono/galactono-kinase
2.7.1.45
2-dehydro-3-deoxygluconokinase
|
–
–
|
|
BRENDA:
BR47415
KEGG:
R01541
MetaCyc:
DEOXYGLUCONOKIN-RXN
|
|
|
|
dTDP-beta-L-mycarose + NADP+ <=> dTDP-3-methyl-4-oxo-2,6-dideoxy-L-allose + NADPH + H+
|
1.1.1
|
–
|
|
KEGG:
R06436
MetaCyc:
RXN-12935
|
|
|
|
6-Deoxocastasterone + O2 + reduced_flavodoxin <=> 6alpha-Hydroxy-castasterone + H2O + flavin
|
1.14
|
–
|
|
KEGG:
R07450
|
|
|
|
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde + H+ <=> 2-aminomuconate_6-semialdehyde + CO2
|
4.1.1.45
aminocarboxymuconate-semialdehyde decarboxylase
|
–
|
|
BRENDA:
BR304
KEGG:
R04323
MetaCyc:
AMINO-CARBOXYMUCONATE-SEMIALDEHYDE-RXN
|
|
|
|
isonocardicin_A <=> nocardicin_A
|
5.1.1.14
nocardicin A epimerase
|
–
|
|
BRENDA:
BR167
KEGG:
R03073
MetaCyc:
NOCARDICIN-A-EPIMERASE-RXN
|
|
|
|
L-Dopa + O2 + H2O <=> 3,4-dihydroxyphenylacetaldehyde + CO2 + NH3 + H2O2
|
4.1.1.107
3,4-dihydroxyphenylacetaldehyde synthase
4.1.1.108
4-hydroxyphenylacetaldehyde synthase
|
–
–
|
|
BRENDA:
BR52267
KEGG:
R11916
MetaCyc:
RXN-19275
|
|
|
|
malonyl-CoA + 6 methylmalonyl-CoA + 6 NADPH + 6 H+ <=> 8,8a-deoxyoleandolide + 7 CoA + 7 CO2 + H2O + 6 NADP+
|
not assigned
|
–
|
|
KEGG:
R06453
|
|
|
|
2,5-dihydroxybenzaldehyde + NAD+ <=> 2,5-Dihydroxybenzoate + NADH
|
1.2.1.29
aryl-aldehyde dehydrogenase
|
–
|
|
BRENDA:
BS189184
KEGG:
R02655
|
|
|
|
dolichyl_phosphate_D-mannose + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> dolichyl_phosphate + alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.260
dolichyl-P-Man:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
|
–
|
|
KEGG:
R06260
|
|
|
|
tryprostatin_B + reduced_flavodoxin + O2 <=> 6-hydroxytryprostatin_B + flavin + H2O
|
1.14.14.118
tryprostatin B 6-hydroxylase
|
–
|
|
BRENDA:
BR50525
KEGG:
R10321
|
|
|
|
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + 2-oxoglutarate <=> UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-hex-4-ulose + L-glutamate
|
2.6.1
2.6.1.34
UDP-N-acetylbacillosamine transaminase
|
–
–
|
|
KEGG:
R12606
MetaCyc:
RXN-17082
|
|
|
|
dTDP-4-dehydro-2,6-dideoxy-alpha-D-glucose <=> dTDP-4-oxo-2,6-dideoxy-L-mannose
|
5.1.3
|
–
|
|
KEGG:
R08597
MetaCyc:
RXN-12928
|
|
|
|
ATP + L-2,3-diaminopropionic_acid + citrate <=> AMP + diphosphate + 2-[(L-alanin-3-ylcarbamoyl)methyl]-2-hydroxybutanedioate + H+
|
6.3.2.54
L-2,3-diaminopropanoate---citrate ligase
|
–
|
|
BRENDA:
BR52706
KEGG:
R12308
MetaCyc:
RXN-19820
|
|
|
|
H+ + UDP-glucuronate <=> UDPapiose + CO2
|
4.1.1
|
–
|
|
KEGG:
R01386
MetaCyc:
RXN-7770
SABIO-RK:
1586
|
|
|
|
dATP + uridine <=> dADP + UMP
|
2.7.1.48
uridine/cytidine kinase
|
–
|
|
BRENDA:
BS357594
KEGG:
R01549
|
|
|
|
3-hydroxypropionate + NAD+ <=> malonate_semialdehyde + NADH + H+
|
1.1.1.298
3-hydroxypropionate dehydrogenase (NADP+)
1.1.1.31
3-hydroxyisobutyrate dehydrogenase
1.1.1.59
3-hydroxypropionate dehydrogenase
1.1.1.60
2-hydroxy-3-oxopropionate reductase
|
–
–
–
–
|
|
BRENDA:
BR29322
KEGG:
R01608
MetaCyc:
3-HYDROXYPROPIONATE-DEHYDROGENASE-RXN
SABIO-RK:
1753
|
|
|
|
UDP-N-acetyl-D-glucosamine + chitin <=> UDP + chitin
|
2.4.1.16
chitin synthase
|
–
|
|
BRENDA:
BR44165
KEGG:
R02335;
R06028
MetaCyc:
CHITIN-SYNTHASE-RXN
|
|
|
|
NADPH + L-sorbose_1-phosphate + H+ <=> NADP+ + D-sorbitol_6-phosphate
|
1.1.1
|
–
|
|
KEGG:
R03234
MetaCyc:
R262-RXN
|
|
|
|
H+ + 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O <=> N-isopropylammelide + ethylamine
|
3.5.4.43
hydroxydechloroatrazine ethylaminohydrolase
|
–
|
|
BRENDA:
BR19265
KEGG:
R05559
MetaCyc:
R122-RXN
SABIO-RK:
5162
|
|
|
|
(S)-malate + H+ <=> L-lactate + CO2
|
4.1.1.101
malolactic enzyme
|
–
|
|
BRENDA:
BR51422
KEGG:
R11074
MetaCyc:
RXN-16819
SABIO-RK:
12493
|
|
|
|
all-trans-retinol + NAD+ <=> all-trans-retinal + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.105
all-trans-retinol dehydrogenase (NAD+)
1.1.1.300
NADP-retinol dehydrogenase
1.1.1.315
11-cis-retinol dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
|
–
–
–
–
–
|
|
BRENDA:
BS186926
KEGG:
R02124
MetaCyc:
RETINOL-DEHYDROGENASE-RXN
SABIO-RK:
2114
|
|
|
|
CMP-N-acetylneuraminate + gibberellin_1 <=> CMP + GM1b
|
2.4.99.4
beta-galactoside alpha-2,3-sialyltransferase
|
–
|
|
KEGG:
R05957
|
|
|
|
alpha-D-glucose_1-phosphate <=> D-glucose_6-phosphate
|
5.4.2.10
phosphoglucosamine mutase
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3
phosphoacetylglucosamine mutase
5.4.2.5
phosphoglucomutase (glucose-cofactor)
5.4.2.8
phosphomannomutase
|
–
–
–
–
–
|
|
BRENDA:
BR18;
BS1162
KEGG:
R08639
MetaCyc:
PHOSPHOGLUCMUT-RXN;
RXN-16999
SABIO-RK:
12817;
7674
|
|
|
|
5-Aminopentanal + NAD+ + H2O <=> 5-Aminopentanoate + NADH + H+
|
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
|
–
–
|
|
BRENDA:
BS189118
KEGG:
R12215
MetaCyc:
RXN0-7318
SABIO-RK:
13011
|
|
|
|
cortisol + NAD+ <=> cortisone + NADH
|
1.1.1
1.1.1.146
11beta-hydroxysteroid dehydrogenase
1.1.1.51
3(or 17)beta-hydroxysteroid dehydrogenase
1.1.1.B40
|
–
–
–
–
|
|
BRENDA:
BS370905
KEGG:
R02834
SABIO-RK:
2700
|
|
|
|
S-adenosyl-L-methionine + genistein <=> H+ + Biochanin_A + S-adenosyl-L-homocysteine
|
2.1.1.155
kaempferol 4'-O-methyltransferase
2.1.1.212
2,7,4'-trihydroxyisoflavanone 4'-O-methyltransferase
2.1.1.231
flavonoid 4'-O-methyltransferase
2.1.1.46
isoflavone 4'-O-methyltransferase
|
–
–
–
–
|
|
BRENDA:
BS289635
KEGG:
R02931
MetaCyc:
RXN-3645
|
|
|
|
naringenin + O2 + reduced_flavodoxin <=> 2,4'',5,7-tetrahydroxyisoflavanone + H2O + flavin
|
1.14.14.87
2-hydroxyisoflavanone synthase
|
–
|
|
BRENDA:
BR50515
KEGG:
R07778
|
|
|
|
acetoacetyl-CoA + H2O + acetyl-CoA <=> H+ + CoA + (S)-3-hydroxy-3-methylglutaryl-CoA
|
2.3.3.10
hydroxymethylglutaryl-CoA synthase
|
–
|
|
BRENDA:
BR44119
KEGG:
R01978
MetaCyc:
HYDROXYMETHYLGLUTARYL-COA-SYNTHASE-RXN
SABIO-RK:
2021
|
|
|
|
CTP + diacylglycerol <=> CDP + phosphatidic_acid + H+
|
2.7.1.174
diacylglycerol kinase (CTP)
|
–
|
|
BRENDA:
BR49008
KEGG:
R09944
MetaCyc:
RXN-12959
|
|
|
|
O-mannose_core_M3 + ATP <=> Phospho-core_M3 + ADP
|
2.7.1.183
glycoprotein-mannosyl O6-kinase
|
–
|
|
KEGG:
R12293
|
|
|
|
S-adenosyl-L-methionine <=> H+ + S-methyl-5''-thioadenosine + 1-aminocyclopropane-1-carboxylate
|
4.4.1.14
1-aminocyclopropane-1-carboxylate synthase
|
–
|
|
BRENDA:
BR3440;
BS368525
KEGG:
R00179
MetaCyc:
4.4.1.14-RXN
SABIO-RK:
732
|
|
|
|
benzoyl-CoA + oxidized_ferredoxin + H2O <=> 4-hydroxybenzoyl-CoA + reduced_ferredoxin
|
1.1.7.1
4-hydroxybenzoyl-CoA reductase
|
–
|
|
BRENDA:
BR29449
KEGG:
R05316
|
|
|
|
1-Nitropropane + H2O + O2 <=> acetone + nitrite + H2O2
|
1.7.3.1
nitroalkane oxidase
|
–
|
|
KEGG:
R10389
|
|
|
|
7alpha-hydroxy-4-cholesten-3-one + ferricytochrome_b5 + H+ + O2 <=> 7alpha,12alpha-dihydroxy-4-cholesten-3-one + ferricytochrome_b5 + H2O
|
1.14.18.8
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase
|
–
|
|
KEGG:
R04826
MetaCyc:
1.14.13.95-RXN
|
|
|
|
shikimate + ATP <=> H+ + 3-phosphoshikimate + ADP
|
2.7.1.71
shikimate kinase
|
–
|
|
BRENDA:
BR47798
KEGG:
R02412
MetaCyc:
SHIKIMATE-KINASE-RXN
SABIO-RK:
2350
|
|
|
|
L-pipecolic_acid + O2 <=> H+ + DELTA1-piperidine_6-carboxylate + H2O2
|
1.5.3.7
L-pipecolate oxidase
|
–
|
|
BRENDA:
BR36911;
BS259362
KEGG:
R02204
MetaCyc:
L-PIPECOLATE-OXIDASE-RXN
SABIO-RK:
2176
|
|
|
|
(2S,3S)-methylcitrate <=> H2O + 2-methyl-trans-aconitate
|
4.2.1.117
2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
4.2.1.79
2-methylcitrate dehydratase
|
–
–
|
|
BRENDA:
BR49126
KEGG:
R11263
MetaCyc:
RXN-8979
|
|
|
|
ATP + UMP <=> ADP + UDP
|
2.7.4.14
UMP/CMP kinase
2.7.4.22
UMP kinase
2.7.4.4
nucleoside-phosphate kinase
2.7.4.8
guanylate kinase
|
–
–
–
–
|
|
BRENDA:
BR48071
KEGG:
R00158
MetaCyc:
RXN-12002
SABIO-RK:
201
|
|
|
|
butyryl-CoA + FAD <=> crotonyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.1
short-chain acyl-CoA dehydrogenase
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
|
|
BRENDA:
BS414397
KEGG:
R01175
SABIO-RK:
1412
|
|
|
|
Betaine_aldehyde + NAD+ + H2O <=> H+ + betaine + NADH
|
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.21
glycolaldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.47
4-trimethylammoniobutyraldehyde dehydrogenase
1.2.1.8
betaine-aldehyde dehydrogenase
|
–
–
–
–
–
–
|
|
BRENDA:
BR36784
KEGG:
R02565
MetaCyc:
BADH-RXN
SABIO-RK:
2478
|
|
|
|
5-COOH-porphyrinogen_I + acceptor <=> Coproporphyrin_I + reduced_acceptor + 6 H+
|
not assigned
|
–
|
|
KEGG:
R04973
|
|
|
|
4-methyl-2-oxopentanoate + thiamine_diphosphate <=> 3-Methyl-1-hydroxybutyl-ThPP + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
KEGG:
R07601
|
|
|
|
N-Carbamoyl-beta-alanine + H2O + H+ <=> beta-Alanine + NH3 + CO2
|
3.5.1.6
beta-ureidopropionase
|
–
|
|
BRENDA:
BR19250
KEGG:
R00905
MetaCyc:
BETA-UREIDOPROPIONASE-RXN
SABIO-RK:
461
|
|
|
|
myristoyl-CoA + FAD <=> 2-tetradecenoyl-CoA + FADH2
|
1.3.3.6
acyl-CoA oxidase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
1.3.8.8
long-chain acyl-CoA dehydrogenase
1.3.8.9
very-long-chain acyl-CoA dehydrogenase
1.3.99
|
–
–
–
–
–
|
|
KEGG:
R03990
SABIO-RK:
3725
|
|
|
|
uridine + GTP <=> H+ + UMP + GDP
|
2.7.1.48
uridine/cytidine kinase
|
–
|
|
BRENDA:
BS357585
KEGG:
R00968
MetaCyc:
URKI-RXN
|
|
|
|
LysW-gamma-L-lysine + H2O <=> L-lysine + [LysW]-C-terminal-L-glutamate
|
3.5.1.130
[amino group carrier protein]-lysine hydrolase
|
–
|
|
KEGG:
R09779
|
|
|
|
an_alcohol + NADP+ <=> an_aldehyde + NADPH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.191
indole-3-acetaldehyde reductase (NADPH)
1.1.1.195
cinnamyl-alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.215
gluconate 2-dehydrogenase
1.1.1.263
1,5-anhydro-D-fructose reductase
1.1.1.265
3-methylbutanal reductase
1.1.1.283
methylglyoxal reductase (NADPH)
1.1.1.4
(R,R)-butanediol dehydrogenase
1.1.1.61
4-hydroxybutyrate dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
1.1.1.72
glycerol dehydrogenase (NADP+)
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.80
isopropanol dehydrogenase (NADP+)
1.1.1.91
aryl-alcohol dehydrogenase (NADP+)
1.1.1.97
3-hydroxybenzyl-alcohol dehydrogenase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29248;
BS139551
KEGG:
R00625;
R00746;
R07328
MetaCyc:
ALCOHOL-DEHYDROGENASE-NADP+-RXN;
ALCOHOL-DEHYDROGENASE-NADPORNOP+-RXN;
RXN-12484
SABIO-RK:
49
|
|
|
|
H2O + GTP <=> H+ + diphosphate + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate + formate
|
3.5.4.25
GTP cyclohydrolase II
|
–
|
|
BRENDA:
BR26117
KEGG:
R00425
MetaCyc:
GTP-CYCLOHYDRO-II-RXN
SABIO-RK:
880
|
|
|
|
L-arginine + succinyl-CoA <=> H+ + N2-succinyl-L-arginine + CoA
|
2.3.1.109
arginine N-succinyltransferase
|
–
|
|
BRENDA:
BR43973
KEGG:
R00832
MetaCyc:
ARGININE-N-SUCCINYLTRANSFERASE-RXN
|
|
|
|
cis-3,4-leucopelargonidin + NADP+ <=> (+)-dihydrokaempferol + NADPH + H+
|
1.1.1.219
dihydroflavonol 4-reductase
|
–
|
|
BRENDA:
BS230655;
BS394832
KEGG:
R03123
MetaCyc:
DIHYDROKAEMPFEROL-4-REDUCTASE-RXN
|
|
|
|
L-gulono-1,4-lactone + NADP+ <=> D-glucuronolactone + NADPH + H+
|
1.1.1.19
glucuronate reductase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.20
glucuronolactone reductase
1.1.1.21
aldose reductase
|
–
–
–
–
|
|
BRENDA:
BR29249
KEGG:
R03183
MetaCyc:
GLUCURONOLACTONE-REDUCTASE-RXN
SABIO-RK:
3012
|
|
|
|
acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate <=> CoA + 2-acetyl-1-O-alkyl-sn-glycero-3-phosphoric_acid
|
2.3.1.105
alkylglycerophosphate 2-O-acetyltransferase
|
–
|
|
KEGG:
R03455
|
|
|
|
geranyl_diphosphate <=> (+)-camphene + diphosphate
|
4.2.3.116
(+)-camphene synthase
4.2.3.20
(R)-limonene synthase
|
–
–
|
|
BRENDA:
BR50079
KEGG:
R09971
MetaCyc:
RXN-8576
|
|
|
|
Pectin + H2O <=> pectate + methanol + H+
|
3.1.1.11
pectinesterase
|
–
|
|
BRENDA:
BR12742
KEGG:
R02362;
R06250
MetaCyc:
RXN-19782
SABIO-RK:
2309
|
|
|
|
ribitol + NAD+ <=> D-ribulose + NADH + H+
|
1.1.1.114
apiose 1-reductase
1.1.1.14
L-iditol 2-dehydrogenase
1.1.1.287
D-arabinitol dehydrogenase (NADP+)
1.1.1.56
ribitol 2-dehydrogenase
1.1.1.9
D-xylulose reductase
|
–
–
–
–
–
|
|
BRENDA:
BR29319
KEGG:
R01895
MetaCyc:
RIBITOL-2-DEHYDROGENASE-RXN
SABIO-RK:
1953
|
|
|
|
cathenamine <=> 4,21-Dehydrogeissoschizine
|
not assigned
|
–
|
|
KEGG:
R05846
MetaCyc:
RXN-19979
|
|
|
|
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin_alpha3(I) <=> dTDP + Calicheamicin_gamma(1)I
|
2.4.2
|
–
|
|
KEGG:
R11421
|
|
|
|
4-coumaroyl-CoA + shikimate <=> 4-coumaroylshikimate + CoA
|
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
2.3.1.140
rosmarinate synthase
2.3.1.99
quinate O-hydroxycinnamoyltransferase
|
–
–
–
|
|
BRENDA:
BR43994
KEGG:
R02416
MetaCyc:
2.3.1.133-RXN
|
|
|
|
D-ribulose_5-phosphate <=> H+ + formate + L-3,4-dihydroxybutan-2-one_4-phosphate
|
4.1.99.12
3,4-dihydroxy-2-butanone-4-phosphate synthase
|
–
|
|
BRENDA:
BR48836
KEGG:
R07281
MetaCyc:
DIOHBUTANONEPSYN-RXN
SABIO-RK:
9052
|
|
|
|
2-deoxy-D-ribose + ATP <=> 2-deoxy-D-ribose_5-phosphate + ADP + H+
|
2.7.1.15
ribokinase
2.7.1.229
deoxyribokinase
|
–
–
|
|
BRENDA:
BR52926
KEGG:
R02750
MetaCyc:
RXN-14223
SABIO-RK:
375
|
|
|
|
paraxanthine + NADPH + O2 + H+ <=> 7-methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.178
methylxanthine N1-demethylase
|
–
–
|
|
BRENDA:
BR50579
KEGG:
R07958
MetaCyc:
RXN-11517
|
|
|
|
pyridoxamine_5''-phosphate + H2O <=> pyridoxamine + phosphate
|
3.1.3.2
acid phosphatase
3.1.3.74
pyridoxal phosphatase
|
–
–
|
|
BRENDA:
BS374481
KEGG:
R02494
MetaCyc:
RXN-14046
SABIO-RK:
2424
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->6)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->6)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.201
alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
–
|
|
KEGG:
R05992
|
|
|
|
ATP + alpha-D-glucose <=> ADP + alpha-D-glucose_6-phosphate
|
2.7.1.1
hexokinase
2.7.1.2
glucokinase
|
–
–
|
|
KEGG:
R01786
SABIO-RK:
10
|
|
|
|
ITP + uridine <=> IDP + UMP
|
2.7.1.48
uridine/cytidine kinase
|
–
|
|
BRENDA:
BS357587
KEGG:
R00970
|
|
|
|
L-glutamate + L-2-aminobutanoate + ATP <=> gamma-Glu-2-aminobutyrate + ADP + phosphate + H+
|
6.3.2.2
glutamate---cysteine ligase
|
–
|
|
BRENDA:
BS369089
KEGG:
R10993
MetaCyc:
RXN-20400
SABIO-RK:
7203
|
|
|
|
Fe-coproporphyrin_III + H+ <=> coproporphyrin_III + Fe2+
|
4.99.1.9
coproporphyrin ferrochelatase
|
–
|
|
BRENDA:
BR51722
KEGG:
R11329
MetaCyc:
RXN-17518
|
|
|
|
1-phosphatidyl-1D-myo-inositol_3,5-bisphosphate + H2O <=> 1-phosphatidyl-1D-myo-inositol_5-phosphate + phosphate
|
3.1.3
3.1.3.36
phosphoinositide 5-phosphatase
3.1.3.56
inositol-polyphosphate 5-phosphatase
3.1.3.95
phosphatidylinositol-3,5-bisphosphate 3-phosphatase
|
–
–
–
–
|
|
BRENDA:
BR50989;
BS380869
KEGG:
R10928;
R12124
MetaCyc:
RXN-10938;
RXN-10958
SABIO-RK:
14198
|
|
|
|
riboflavin + alpha-D-glucose_1-phosphate <=> FMN + D-glucose
|
2.7.1.42
riboflavin phosphotransferase
|
–
|
|
BRENDA:
BR47427;
BS353978
KEGG:
R00550
MetaCyc:
RIBOFLAVIN-PHOSPHOTRANSFERASE-RXN
|
|
|
|
(2R)-3-sulfolactate <=> pyruvate + sulfite + H+
|
4.4.1.24
(2R)-sulfolactate sulfo-lyase
|
–
|
|
BRENDA:
BR48704
KEGG:
R07633
MetaCyc:
RXN-11691
|
|
|
|
L-glutamine + pyruvate <=> 2-Oxoglutaramate + L-alanine
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.51
serine---pyruvate transaminase
|
–
–
|
|
BRENDA:
BR47673
KEGG:
R00576
MetaCyc:
GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN
SABIO-RK:
977
|
|
|
|
(2E,4Z)-2-hydroxy-5-methylhexa-2,4-diendioate <=> 2-Oxo-5-methyl-cis-muconate
|
5.3.2.6
2-hydroxymuconate tautomerase
|
–
|
|
KEGG:
R05389
|
|
|
|
H2O + 2-O-(alpha-D-mannopyranosyl)-3-phospho-D-glycerate <=> 2-O-(alpha-D-mannopyranosyl)-D-glycerate + phosphate
|
3.1.3.70
mannosyl-3-phosphoglycerate phosphatase
3.1.3.85
glucosyl-3-phosphoglycerate phosphatase
|
–
–
|
|
BRENDA:
BR36950
KEGG:
R05790
MetaCyc:
3.1.3.70-RXN
SABIO-RK:
5381
|
|
|
|
H2O + 3-phospho-D-glycerate <=> D-glycerate + phosphate
|
3.1.3.10
glucose-1-phosphatase
3.1.3.19
glycerol-2-phosphatase
3.1.3.2
acid phosphatase
3.1.3.20
phosphoglycerate phosphatase
3.1.3.26
4-phytase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.38
3-phosphoglycerate phosphatase
3.1.3.58
sugar-terminal-phosphatase
3.1.3.60
phosphoenolpyruvate phosphatase
3.1.3.8
3-phytase
|
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR10689;
BS64594
KEGG:
R01511
MetaCyc:
3-PHOSPHOGLYCERATE-PHOSPHATASE-RXN
SABIO-RK:
10377;
1683
|
|
|
|
UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol <=> 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-glucopyranosyl)-sn-glycerol + UDP + H+
|
2.4.1.208
diglucosyl diacylglycerol synthase (1,2-linking)
|
–
|
|
BRENDA:
BR44193
KEGG:
R05164
MetaCyc:
2.4.1.208-RXN
|
|
|
|
7,8-dihydroneopterin_3''-phosphate + H2O <=> 7,8-dihydroneopterin + phosphate
|
3.6.1
|
–
|
|
KEGG:
R04621
MetaCyc:
DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN
|
|
|
|
H+ + cumic_acid + NADH + O2 <=> cis-5,6-dihydroxy-4-isopropylcyclohexa-1,3-dienecarboxylate + NAD+
|
1.14.12.25
p-cumate 2,3-dioxygenase
|
–
|
|
BRENDA:
BR51797
KEGG:
R05247
MetaCyc:
RXN-664
|
|
|
|
naringenin + 2-oxoglutarate + O2 <=> (+)-dihydrokaempferol + succinate + CO2
|
1.14.11.9
flavanone 3-dioxygenase
|
–
|
|
BRENDA:
BS288657;
BS402787
KEGG:
R02444
MetaCyc:
NARINGENIN-3-DIOXYGENASE-RXN
|
|
|
|
H2O + formyl-CoA <=> H+ + formate + CoA
|
3.1.2.10
formyl-CoA hydrolase
|
–
|
|
BRENDA:
BR10670
KEGG:
R00521
MetaCyc:
FORMYL-COA-HYDROLASE-RXN
|
|
|
|
N-acetylneuraminate + CTP <=> CMP-N-acetylneuraminate + diphosphate
|
2.7.7.43
N-acylneuraminate cytidylyltransferase
2.7.7.92
3-deoxy-D-glycero-D-galacto-nonulopyranosonate cytidylyltransferase
|
–
–
|
|
BRENDA:
BS388407
KEGG:
R01117
MetaCyc:
RXN-9990
SABIO-RK:
1376
|
|
|
|
GDP-L-fucose + paragloboside <=> GDP + Fuc-Lc4Cer
|
2.4.1.65
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase
|
–
|
|
KEGG:
R06155
|
|
|
|
Mithramycin_DK <=> mithramycin
|
not assigned
|
–
|
|
KEGG:
R09354
|
|
|
|
L-lactate <=> formate + acetaldehyde
|
4.1.2.36
lactate aldolase
|
–
|
|
BRENDA:
BR48322
KEGG:
R00753
MetaCyc:
LACTATE-ALDOLASE-RXN
|
|
|
|
D-myo-Inositol_3,4-bisphosphate + H2O <=> D-myo-Inositol_1-phosphate + phosphate
|
3.1.3.66
phosphatidylinositol-3,4-bisphosphate 4-phosphatase
|
–
|
|
KEGG:
R04372
MetaCyc:
RXN-10960
|
|
|
|
nitroethane + O2 + FMNH2 <=> acetaldehyde + nitrite + H2O + FMN + H+
|
1.13.12.16
nitronate monooxygenase
1.7.3.1
nitroalkane oxidase
|
–
–
|
|
BRENDA:
BR47600
KEGG:
R00025
MetaCyc:
2-NITROPROPANE-DIOXYGENASE-RXN
|
|
|
|
Cl- + hydroquinone + GSSG + H+ <=> chlorohydroquinone + glutathione
|
2.5.1
|
–
|
|
KEGG:
R05267
MetaCyc:
RXN-12506
|
|
|
|
NAD+ + glycine + Sulfide <=> nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + H2O + H+
|
2.4.2.59
sulfide-dependent adenosine diphosphate thiazole synthase
|
–
|
|
BRENDA:
BR52368
KEGG:
R12026
MetaCyc:
RXN-19351
|
|
|
|
trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide + H2O <=> 2-chloromaleylacetate + H+
|
3.1.1.45
carboxymethylenebutenolidase
|
–
|
|
KEGG:
R05511
MetaCyc:
DIENELACHYDRO-RXN;
RXN-9857
|
|
|
|
malonyl-[acyl-carrier_protein]_methyl_ester + malonyl-[acyl-carrier_protein] + H+ <=> 3-Ketoglutaryl-[acp]_methyl_ester + CO2 + [acyl-carrier_protein]
|
2.3.1.179
beta-ketoacyl-[acyl-carrier-protein] synthase II
2.3.1.41
beta-ketoacyl-[acyl-carrier-protein] synthase I
|
–
–
|
|
KEGG:
R10115
MetaCyc:
RXN-11474
|
|
|
|
phenylpyruvate + acetyl-CoA + H2O <=> 2-Benzylmalate + CoA + H+
|
2.3.3
|
–
|
|
KEGG:
R10500
MetaCyc:
RXN-14462
|
|
|
|
D-ribulose_1,5-bisphosphate + O2 <=> 2-Phosphoglycolate + 3-phospho-D-glycerate + H+
|
1.13.11
4.1.1.39
ribulose-bisphosphate carboxylase
|
–
–
|
|
BRENDA:
BS1442
KEGG:
R03140
MetaCyc:
RXN-961
SABIO-RK:
8708
|
|
|
|
L-adrenaline + H2O + O2 <=> 3,4-dihydroxyphenylglycolaldehyde + methylamine + H2O2
|
1.4.3.4
monoamine oxidase
|
–
|
|
KEGG:
R02919
MetaCyc:
RXN-10908
|
|
|
|
acetaldehyde + CoA + NAD+ <=> acetyl-CoA + NADH + H+
|
1.2.1.10
acetaldehyde dehydrogenase (acetylating)
1.2.1.42
hexadecanal dehydrogenase (acylating)
1.2.1.57
butanal dehydrogenase
1.2.1.87
propanal dehydrogenase (CoA-propanoylating)
|
–
–
–
–
|
|
BRENDA:
BR36771
KEGG:
R00228
MetaCyc:
ACETALD-DEHYDROG-RXN
SABIO-RK:
163
|
|
|
|
loganin + reduced_flavodoxin + O2 <=> secologanin + flavin + 2 H2O
|
1.14.19.62
secologanin synthase
|
–
|
|
BRENDA:
BR40360
KEGG:
R03555
|
|
|
|
3-dehydro-L-gulonate + NADP+ <=> (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NADPH + H+
|
1.1.1.130
3-dehydro-L-gulonate 2-dehydrogenase
|
–
|
|
BRENDA:
BR29197
KEGG:
R02639
MetaCyc:
3-DEHYDRO-L-GULONATE-2-DEHYDROGENASE-RXN
|
|
|
|
S-adenosyl-L-methionine + Tetracenomycin_E <=> tetracenomycin_A2 + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R06703
MetaCyc:
RXN-15436
|
|
|
|
geranyl_diphosphate + H2O <=> Sabinene_hydrate + diphosphate
|
4.2.3.11
sabinene-hydrate synthase
|
–
|
|
BRENDA:
BR48349
KEGG:
R02006
MetaCyc:
4.2.3.11-RXN
|
|
|
|
H+ + alpha-D-mannose_1-phosphate + GTP <=> GDP-mannose + diphosphate
|
2.7.7.13
mannose-1-phosphate guanylyltransferase
2.7.7.28
nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase
2.7.7.30
fucose-1-phosphate guanylyltransferase
2.7.7.34
glucose-1-phosphate guanylyltransferase
|
–
–
–
–
|
|
BRENDA:
BR47862;
BS358533
KEGG:
R00885
MetaCyc:
2.7.7.13-RXN
SABIO-RK:
15252;
587;
8539
|
|
|
|
ATP + L-xylulose <=> ADP + L-xylulose_1-phosphate
|
2.7.1.5
rhamnulokinase
|
–
|
|
BRENDA:
BS357629
KEGG:
R01902
|
|
|
|
S-adenosyl-L-methionine + N-acetylserotonin <=> H+ + S-adenosyl-L-homocysteine + Melatonin
|
2.1.1.4
acetylserotonin O-methyltransferase
|
–
|
|
BRENDA:
BR40580
KEGG:
R03130
MetaCyc:
ACETYLSEROTONIN-O-METHYLTRANSFERASE-RXN
SABIO-RK:
2965
|
|
|
|
(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA + NAD+ <=> H+ + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA + NADH
|
1.1.1
|
–
|
|
KEGG:
R04812
MetaCyc:
RXN-9799
|
|
|
|
H+ + phosphoenolpyruvate <=> Phosphonopyruvate
|
5.4.2.9
phosphoenolpyruvate mutase
|
–
|
|
BRENDA:
BR48374
KEGG:
R00661
MetaCyc:
PHOSPHOENOLPYRUVATE-MUTASE-RXN
|
|
|
|
(3E,3'E)-1,1'-dimethoxy-3,3',4,4'-tetradehydro-1,1',2,2'-tetrahydro-psi,psi-caroten-2-one + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> 2,2''-dioxospirilloxanthin + oxidized_ferredoxin + H2O
|
1.14.15.9
spheroidene monooxygenase
|
–
|
|
BRENDA:
BR50111
KEGG:
R07526
MetaCyc:
RXN-11653
|
|
|
|
O2 + L-tryptophan <=> Indole-3-acetamide + H2O + CO2
|
1.13.12.3
tryptophan 2-monooxygenase
|
–
|
|
BRENDA:
BR40465
KEGG:
R00679
MetaCyc:
TRYPTOPHAN-2-MONOOXYGENASE-RXN
SABIO-RK:
1059
|
|
|
|
L-Histidinol + NAD+ <=> H+ + L-histidinal + NADH
|
1.1.1.23
histidinol dehydrogenase
|
–
|
|
BRENDA:
BS371011
KEGG:
R03012
MetaCyc:
HISTOLDEHYD-RXN
|
|
|
|
H+ + L-pyrroline-5-carboxylate + malonyl-CoA + H2O <=> (2S,5S)-5-carboxymethylproline + CoA + CO2
|
2.3.1.226
carboxymethylproline synthase
|
–
|
|
BRENDA:
BR50641
KEGG:
R10485
MetaCyc:
RXN-8947
SABIO-RK:
7117
|
|
|
|
CoA + oxalate + ATP <=> oxalyl-CoA + diphosphate + AMP
|
6.2.1.8
oxalate---CoA ligase
|
–
|
|
BRENDA:
BR91
KEGG:
R01558
MetaCyc:
OXALATE--COA-LIGASE-RXN
|
|
|
|
meso-2,6-diaminoheptanedioate + NADP+ + H2O <=> L-2-amino-6-oxopimelate + NH3 + NADPH + H+
|
1.4.1.16
diaminopimelate dehydrogenase
|
–
|
|
BRENDA:
BR36864
KEGG:
R02755
MetaCyc:
DIAMINOPIMELATE-DEHYDROGENASE-RXN
|
|
|
|
2-chloro-3-oxohexanedioic_acid <=> Chloroacetate + succinate
|
not assigned
|
–
|
|
KEGG:
R06855
|
|
|
|
N-formylmaleamic_acid + H2O <=> H+ + Maleamate + formate
|
3.5.1.106
N-formylmaleamate deformylase
|
–
|
|
BRENDA:
BR49200
KEGG:
R09126
MetaCyc:
RXN-11318
|
|
|
|
L-Histidinol_phosphate + H2O <=> L-Histidinol + phosphate
|
3.1.3.15
histidinol-phosphatase
3.1.3.2
acid phosphatase
|
–
–
|
|
BRENDA:
BR19199
KEGG:
R03013
MetaCyc:
HISTIDPHOS-RXN
|
|
|
|
monoacylglycerol + H2O <=> glycerol + fatty_acid + H+
|
3.1.1.23
acylglycerol lipase
3.1.1.3
triacylglycerol lipase
3.1.1.67
fatty-acyl-ethyl-ester synthase
3.1.1.79
hormone-sensitive lipase
|
–
–
–
–
|
|
BRENDA:
BR11710;
BR48143;
BS360684
KEGG:
R01351;
R07293
MetaCyc:
3.1.1.23-RXN;
RXN-19280
|
|
|
|
Premithramycin_B + NADPH + H+ + O2 <=> Mithramycin_DK + NADP+ + CO2
|
1.14.13
|
–
|
|
KEGG:
R09353
|
|
|
|
3-Hydroxy-OPC8-CoA + NAD+ <=> 3-Oxo-OPC8-CoA + NADH + H+
|
1.1.1.211
long-chain-3-hydroxyacyl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
KEGG:
R07890
|
|
|
|
2,5-Dihydroxybenzoate + O2 <=> maleylpyruvate + H+
|
1.13.11.4
gentisate 1,2-dioxygenase
1.13.11.86
5-aminosalicylate 1,2-dioxygenase
|
–
–
|
|
BRENDA:
BR36757
KEGG:
R02656
MetaCyc:
GENTISATE-12-DIOXYGENASE-RXN
SABIO-RK:
2552
|
|
|
|
N,N-dihydroxy-L-phenylalanine + H+ <=> (E)-phenylacetaldoxime + CO2 + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
|
BRENDA:
BR49592
KEGG:
R09581
MetaCyc:
RXN-12068
|
|
|
|
ATP + N-Acetyl-L-Asp-L-Glu + L-glutamate <=> ADP + phosphate + N-acetyl-L-aspartyl-L-glutamyl-L-glutamate
|
6.3.2.42
N-acetylaspartylglutamylglutamate synthase
|
–
|
|
KEGG:
R10693
|
|
|
|
linoleic_acid + O2 <=> (9Z,11E,13S)-13-hydroperoxy-9,11-octadecadienoate
|
1.13.11.12
linoleate 13S-lipoxygenase
1.13.11.31
arachidonate 12-lipoxygenase
1.13.11.33
arachidonate 15-lipoxygenase
1.13.11.34
arachidonate 5-lipoxygenase
|
–
–
–
–
|
|
BRENDA:
BR37113
KEGG:
R03626
MetaCyc:
LIPOXYGENASE-RXN
SABIO-RK:
3408
|
|
|
|
ITP + D-tagatose_6-phosphate <=> IDP + D-tagatose_1,6-bisphosphate
|
2.7.1.11
6-phosphofructokinase
2.7.1.144
tagatose-6-phosphate kinase
|
–
–
|
|
BRENDA:
BS357292
KEGG:
R03239
|
|
|
|
ceramide + phosphatidylcholine <=> sphingomyelin + diacylglycerol
|
2.7.8.27
sphingomyelin synthase
|
–
|
|
BRENDA:
BR48769
KEGG:
R08969
MetaCyc:
2.7.8.27-RXN
|
|
|
|
S-adenosyl-L-methionine + gamma-tocotrienol <=> S-adenosyl-L-homocysteine + alpha-tocotrienol + H+
|
2.1.1.95
tocopherol C-methyltransferase
|
–
|
|
BRENDA:
BR52801
KEGG:
R10491
MetaCyc:
RXN-14918
|
|
|
|
phosphoenolpyruvate + 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose + H2O <=> 5,7-bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic_acid + phosphate
|
2.5.1.97
pseudaminic acid synthase
|
–
|
|
BRENDA:
BR49897
KEGG:
R09841
MetaCyc:
RXN-10002
|
|
|
|
S-adenosyl-L-methionine + 3-Indole-2-oxopropanoate <=> S-adenosyl-L-homocysteine + 3-Methylindolepyruvate
|
2.1.1.47
indolepyruvate C-methyltransferase
|
–
|
|
KEGG:
R01973
|
|
|
|
5,6-Dihydroxyindole-2-carboxylate + O2 <=> indole-5,6-quinone-2-carboxylic_acid + H2O
|
1.14.18
1.14.18.B1
|
–
–
|
|
BRENDA:
BR52495
KEGG:
R08965
|
|
|
|
3-(methylthio)propanoate + 5-methyltetrahydrofolate + H+ <=> dimethylsulfoniopropionate + tetrahydrofolate
|
2.1.1.269
dimethylsulfoniopropionate demethylase
|
–
|
|
BRENDA:
BR49172
KEGG:
R10333
MetaCyc:
RXN-9736
|
|
|
|
Styrene + O2 + NADH + H+ <=> Styrene-cis-2,3-dihydrodiol + NAD+
|
1.14.12
|
–
|
|
KEGG:
R05417
|
|
|
|
CoA + 4-hydroxybenzoate + ATP <=> 4-hydroxybenzoyl-CoA + diphosphate + AMP
|
6.2.1.27
4-hydroxybenzoate---CoA ligase
|
–
|
|
BRENDA:
BR48381
KEGG:
R01300
MetaCyc:
4-HYDROXYBENZOATE--COA-LIGASE-RXN
SABIO-RK:
1515
|
|
|
|
3-phospho-D-glycerate + NAD+ <=> H+ + 3-phosphohydroxypyruvate + NADH
|
1.1.1.95
phosphoglycerate dehydrogenase
|
–
|
|
BRENDA:
BR29351;
BS188712
KEGG:
R01513
MetaCyc:
PGLYCDEHYDROG-RXN
SABIO-RK:
1684;
8970
|
|
|
|
D-glucose_6-phosphate <=> D-myo-Inositol_1-phosphate
|
5.5.1.4
inositol-3-phosphate synthase
|
–
|
|
BRENDA:
BR262
KEGG:
R07324
MetaCyc:
MYO-INOSITOL-1-PHOSPHATE-SYNTHASE-RXN
SABIO-RK:
1181
|
|
|
|
glycine + H2O + 2 ferricytochrome_c <=> glyoxylate + NH3 + 2 ferricytochrome_c + 2 H+
|
1.4.2.1
glycine dehydrogenase (cytochrome)
|
–
|
|
BRENDA:
BR36872
KEGG:
R00364
|
|
|
|
ATP + (R)-pantoate <=> H+ + ADP + (R)-4-phosphopantoate
|
2.7.1.169
pantoate kinase
|
–
|
|
BRENDA:
BR49258;
BS407155
KEGG:
R09378
MetaCyc:
RXN-11782
|
|
|
|
3-ethylcatechol + O2 <=> 2-hydroxy-6-oxoocta-2,4-dienoate
|
1.13.11
1.13.11.16
3-carboxyethylcatechol 2,3-dioxygenase
|
–
–
|
|
BRENDA:
BS260804
KEGG:
R05416
SABIO-RK:
5022
|
|
|
|
methanesulfonate + O2 + FMNH2 <=> formaldehyde + sulfite + FMN + H2O + H+
|
1.14.14.34
methanesulfonate monooxygenase (FMNH2)
1.14.14.5
alkanesulfonate monooxygenase
|
–
–
|
|
BRENDA:
BR51813
KEGG:
R10206
MetaCyc:
RXN-18086
|
|
|
|
2-deoxy-alpha-D-ribose_1-phosphate <=> 2-deoxy-D-ribose_5-phosphate
|
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.7
phosphopentomutase
5.4.2.8
phosphomannomutase
|
–
–
–
|
|
BRENDA:
BS1184
KEGG:
R02749
MetaCyc:
D-PPENTOMUT-RXN
SABIO-RK:
87
|
|
|
|
[LysW]-C-terminal-gamma-(L-2-aminoadip-2-yl)-L-glutamate + ATP <=> LysW-gamma-L-alpha-aminoadipyl_6-phosphate + ADP
|
2.7.2.17
[amino-group carrier protein]-L-2-aminoadipate 6-kinase
|
–
|
|
KEGG:
R09776
|
|
|
|
strictosidine + H2O <=> strictosidine_aglycone + D-glucose
|
3.2.1.105
3alpha(S)-strictosidine beta-glucosidase
3.2.1.125
raucaffricine beta-glucosidase
|
–
–
|
|
BRENDA:
BR15979
KEGG:
R03820
MetaCyc:
STRICTOSIDINE-BETA-GLUCOSIDASE-RXN
|
|
|
|
H+ + carboxynorspermidine <=> norspermidine + CO2
|
4.1.1.96
carboxynorspermidine decarboxylase
|
–
|
|
BRENDA:
BR50201
KEGG:
R09082
MetaCyc:
RXN-9380
|
|
|
|
pyruvate + dGTP <=> phosphoenolpyruvate + dGDP + H+
|
2.7.1.40
pyruvate kinase
|
–
|
|
BRENDA:
BS411977
KEGG:
R01858
MetaCyc:
RXN-14207
SABIO-RK:
284
|
|
|
|
beta-D-glucose_6-phosphate + NADP+ <=> 6-phospho-D-glucono-1,5-lactone + NADPH
|
1.1.1.363
glucose-6-phosphate dehydrogenase [NAD(P)+]
1.1.1.47
glucose 1-dehydrogenase [NAD(P)+]
1.1.1.49
glucose-6-phosphate dehydrogenase (NADP+)
|
–
–
–
|
|
BRENDA:
BS355829;
BS355830
KEGG:
R02736
SABIO-RK:
18
|
|
|
|
H+ + lipoic_acid + ATP <=> lipoyl-AMP + diphosphate
|
6.3.1.20
lipoate---protein ligase
|
–
|
|
BRENDA:
BR48678
KEGG:
R07770
MetaCyc:
RXN-8654
|
|
|
|
2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl_phosphate <=> 2-(2-carboxy-4-methylthiazol-5-yl)ethyl_phosphate
|
5.3.99.10
thiazole tautomerase
|
–
|
|
BRENDA:
BR50087
KEGG:
R09977
MetaCyc:
RXN-12609
|
|
|
|
Cholesta-5,7,24-trienol + NADPH + H+ <=> 7-dehydrocholesterol + NADP+
|
1.3.1.72
Delta24-sterol reductase
|
–
|
|
BRENDA:
BS189404
KEGG:
R07507
|
|
|
|
N,N-dihydroxy-L-valine + H+ <=> (E)-2-methylpropanal-oxime + CO2 + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
|
BRENDA:
BR49383
KEGG:
R10033
MetaCyc:
RXN-5065
|
|
|
|
H+ + Urea + H2O <=> NH3 + CO2
|
3.5.1.5
urease
|
–
|
|
BRENDA:
BR22694
KEGG:
R00131
MetaCyc:
UREASE-RXN
SABIO-RK:
289
|
|
|
|
8-demethyltetracenomycin_C + dTDP-L-rhamnose <=> 8-demethyl-8-alpha-L-rhamnosyl_tetracenomycin_C + dTDP + H+
|
2.4.1.331
8-demethyltetracenomycin C L-rhamnosyltransferase
|
–
|
|
BRENDA:
BR50871
KEGG:
R10955
MetaCyc:
RXN-15406
|
|
|
|
Chloroacetate + H2O <=> H+ + glycolate + Cl-
|
3.8.1.10
2-haloacid dehalogenase (configuration-inverting)
3.8.1.2
(S)-2-haloacid dehalogenase
3.8.1.3
haloacetate dehalogenase
3.8.1.5
haloalkane dehalogenase
3.8.1.9
(R)-2-haloacid dehalogenase
|
–
–
–
–
–
|
|
BRENDA:
BS141612
KEGG:
R05287
MetaCyc:
DHLBXANAU-RXN
|
|
|
|
D-ornithine + H+ <=> putrescine + CO2
|
4.1.1.116
D-ornithine/D-lysine decarboxylase
6707
|
–
–
|
|
BRENDA:
BR52449
KEGG:
R12304
MetaCyc:
RXN-20175
|
|
|
|
S-adenosyl-L-methionine + demethylphylloquinol <=> vitamin_KH2 + S-adenosyl-L-homocysteine + H+
|
2.1.1.329
demethylphylloquinol methyltransferase
|
–
|
|
BRENDA:
BR51848
KEGG:
R04994
MetaCyc:
RXN-7569
|
|
|
|
5-Aminopentanoate <=> D-proline
|
1.21.4.1
D-proline reductase
1.4.1.12
2,4-diaminopentanoate dehydrogenase
|
–
–
|
|
KEGG:
R02825
|
|
|
|
H+ + AMP + H2O <=> IMP + NH3
|
3.5.4.17
adenosine-phosphate deaminase
3.5.4.4
adenosine deaminase
3.5.4.6
AMP deaminase
3.5.4.7
ADP deaminase
|
–
–
–
–
|
|
BRENDA:
BR22743
KEGG:
R00181
MetaCyc:
AMP-DEAMINASE-RXN
SABIO-RK:
135
|
|
|
|
1-methyl-1H-imidazol-4-ylacetaldehyde + NAD+ + H2O <=> Methylimidazoleacetic_acid + NADH + H+
|
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
|
–
|
|
KEGG:
R04996
|
|
|
|
spermine + O2 + H2O <=> spermidine + 3-aminopropionaldehyde + H2O2
|
1.5.3.16
spermine oxidase
1.5.3.17
non-specific polyamine oxidase
|
–
–
|
|
BRENDA:
BR48997
KEGG:
R09076
MetaCyc:
RXN-9015
SABIO-RK:
7728
|
|
|
|
glucobrassicin + H2O <=> indole-3-acetonitrile + D-glucose + sulfate + sulfur
|
3.2.1.147
thioglucosidase
|
–
|
|
KEGG:
R04094
|
|
|
|
2''-deoxyuridine + ATP <=> H+ + dUMP + ADP
|
2.7.1.145
deoxynucleoside kinase
2.7.1.21
thymidine kinase
2.7.1.74
deoxycytidine kinase
2.7.1.76
2'-deoxyadenosine kinase
|
–
–
–
–
|
|
BRENDA:
BS353774
KEGG:
R02099
MetaCyc:
DURIDKI-RXN
SABIO-RK:
500
|
|
|
|
L-cystathionine + H2O <=> L-homocysteine + pyruvate + NH3
|
2.5.1.48
cystathionine gamma-synthase
3.5.1.61
mimosinase
4.2.1.22
cystathionine beta-synthase
4.4.1.1
cystathionine gamma-lyase
4.4.1.13
cysteine-S-conjugate beta-lyase
4.4.1.28
L-cysteine desulfidase
4.4.1.3
dimethylpropiothetin dethiomethylase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR3446
KEGG:
R01286
MetaCyc:
CYSTATHIONINE-BETA-LYASE-RXN
SABIO-RK:
1500;
1501
|
|
|
|
ATP + dUMP <=> ADP + dUDP
|
2.7.4.13
(deoxy)nucleoside-phosphate kinase
2.7.4.14
UMP/CMP kinase
2.7.4.22
UMP kinase
2.7.4.25
(d)CMP kinase
2.7.4.4
nucleoside-phosphate kinase
2.7.4.9
dTMP kinase
2.7.4.B1
|
–
–
–
–
–
–
–
|
|
BRENDA:
BS359746
KEGG:
R02098
MetaCyc:
RXN-14122
SABIO-RK:
499
|
|
|
|
UDP-glucose + (1,4-beta-D-glucosyl)n <=> (1,4-beta-D-glucosyl)n + UDP
|
2.4.1.12
cellulose synthase (UDP-forming)
2.4.1.168
xyloglucan 4-glucosyltransferase
|
–
–
|
|
BRENDA:
BS354131
KEGG:
R02889;
R06023
MetaCyc:
CELLULOSE-SYNTHASE-UDP-FORMING-RXN;
RXN-12419
|
|
|
|
chlorophyllide_a + NADP+ <=> protochlorophyllide + NADPH + H+
|
1.3.1.33
protochlorophyllide reductase
|
–
|
|
BRENDA:
BR36964
KEGG:
R03845
SABIO-RK:
3597
|
|
|
|
O-succinyl-L-homoserine + H2O <=> 2-oxobutyrate + succinate + NH3 + H+
|
2.5.1.48
cystathionine gamma-synthase
4.3.1
4.4.1.13
cysteine-S-conjugate beta-lyase
|
–
–
–
|
|
BRENDA:
BS354327
KEGG:
R00999
MetaCyc:
METBALT-RXN
SABIO-RK:
1292
|
|
|
|
succinate_semialdehyde + NADP+ + H2O <=> NADPH + succinate + H+
|
1.1.1.21
aldose reductase
1.2.1.16
succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.79
succinate-semialdehyde dehydrogenase (NADP+)
|
–
–
–
–
–
|
|
BRENDA:
BR29388
KEGG:
R00714
MetaCyc:
RXN0-5293;
SUCCSEMIALDDEHYDROG-RXN
SABIO-RK:
1086
|
|
|
|
D-myo-Inositol_1-phosphate + H2O <=> myo-inositol + phosphate
|
3.1.3.11
fructose-bisphosphatase
3.1.3.2
acid phosphatase
3.1.3.23
sugar-phosphatase
3.1.3.25
inositol-phosphate phosphatase
3.1.3.26
4-phytase
3.1.3.57
inositol-1,4-bisphosphate 1-phosphatase
3.1.3.93
L-galactose 1-phosphate phosphatase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR26031
KEGG:
R01185;
R01187;
R07343
MetaCyc:
MYO-INOSITOL-1OR-4-MONOPHOSPHATASE-RXN;
RXN0-5408
SABIO-RK:
1422;
1424;
9216
|
|
|
|
geranylgeranyl_diphosphate <=> prephytoene_diphosphate + diphosphate
|
2.5.1.148
lycopaoctaene synthase
2.5.1.32
15-cis-phytoene synthase
|
–
–
|
|
BRENDA:
BR47500
KEGG:
R02065
MetaCyc:
2.5.1.32-RXN
SABIO-RK:
2081
|
|
|
|
benzaldehyde + H2O + NAD+ <=> aromatic_carboxylate + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.28
benzaldehyde dehydrogenase (NAD+)
1.2.1.29
aryl-aldehyde dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.31
L-aminoadipate-semialdehyde dehydrogenase
1.2.1.48
long-chain-aldehyde dehydrogenase
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
1.2.1.64
4-hydroxybenzaldehyde dehydrogenase (NAD+)
1.2.1.65
salicylaldehyde dehydrogenase
1.2.1.67
vanillin dehydrogenase
1.2.1.69
fluoroacetaldehyde dehydrogenase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29397;
BR36777
KEGG:
R01419;
R01486
MetaCyc:
ARYL-ALDEHYDE-DEHYDROGENASE-RXN;
BENZALDEHYDE-DEHYDROGENASE-NAD+-RXN
SABIO-RK:
1606
|
|
|
|
2''-deoxyuridine + phosphate <=> 2-deoxy-alpha-D-ribose_1-phosphate + Uracil
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.2
pyrimidine-nucleoside phosphorylase
2.4.2.3
uridine phosphorylase
2.4.2.4
thymidine phosphorylase
|
–
–
–
–
|
|
BRENDA:
BR47487;
BS354611
KEGG:
R02484
MetaCyc:
URA-PHOSPH-RXN
SABIO-RK:
511
|
|
|
|
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O2 <=> H+ + 3-(methylthio)propanoate + formate + CO
|
1.13.11.53
acireductone dioxygenase (Ni2+-requiring)
1.13.11.54
acireductone dioxygenase [iron(II)-requiring]
|
–
–
|
|
BRENDA:
BR48659
KEGG:
R07363
MetaCyc:
R146-RXN
|
|
|
|
L-arogenate + NADP+ <=> L-tyrosine + CO2 + NADPH
|
1.3.1.43
arogenate dehydrogenase
1.3.1.78
arogenate dehydrogenase (NADP+)
1.3.1.79
arogenate dehydrogenase [NAD(P)+]
|
–
–
–
|
|
BRENDA:
BR48485
KEGG:
R00733
MetaCyc:
RXN-14476;
RXN-5682
SABIO-RK:
1096
|
|
|
|
coniferyl_alcohol <=> Guaiacyl_lignin
|
1.11.1.21
catalase-peroxidase
1.11.1.7
peroxidase
|
–
–
|
|
KEGG:
R02596
|
|
|
|
Dihydrolipoyl-AMP + Lipoyl-carrier_protein_E2 <=> Enzyme_N6-(lipoyl)lysine + AMP + 2 H+
|
not assigned
|
–
|
|
KEGG:
R12435
|
|
|
|
6-phosphogluconate + NADP+ <=> 6-phospho-2-dehydro-D-gluconate + NADPH + H+
|
1.1.1.43
phosphogluconate 2-dehydrogenase
|
–
|
|
BRENDA:
BR29306
KEGG:
R02034
MetaCyc:
1.1.1.43-RXN
SABIO-RK:
490
|
|
|
|
2R,3R-2,3-dihydroxy-3-methylpentanoate <=> (S)-3-methyl-2-oxopentanoate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
|
BRENDA:
BS453486
KEGG:
R05070
MetaCyc:
DIHYDROXYMETVALDEHYDRAT-RXN
|
|
|
|
8,8a-deoxyoleandolide + 2 NADPH + 2 H+ + 2 O2 <=> Oleandolide + 2 NADP+ + 3 H2O
|
not assigned
|
–
|
|
KEGG:
R06454
|
|
|
|
heme + H+ <=> protoporphyrin_IX + Fe2+
|
4.99.1.1
protoporphyrin ferrochelatase
4.99.1.9
coproporphyrin ferrochelatase
|
–
–
|
|
BRENDA:
BR3454
KEGG:
R00310
MetaCyc:
PROTOHEMEFERROCHELAT-RXN
SABIO-RK:
802
|
|
|
|
beta-D-Gal6S-(1->4)-beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + H2O <=> beta-D-Gal-(1->4)-beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + sulfate
|
3.1.6.4
N-acetylgalactosamine-6-sulfatase
|
–
|
|
KEGG:
R07806
|
|
|
|
1-hydroxy-2-naphthoate + NADH + O2 + H+ <=> 1,2-dihydroxynaphthalene + NAD+ + H2O + CO2
|
1.14.13.1
salicylate 1-monooxygenase
1.14.13.135
1-hydroxy-2-naphthoate hydroxylase
|
–
–
|
|
BRENDA:
BR49863-a
KEGG:
R05632
MetaCyc:
RXN-12763_WOP
|
|
|
|
geranyl_diphosphate + 2,4-dihydroxy-6-pentylbenzoate <=> cannabigerolate + diphosphate
|
2.5.1.102
geranyl-pyrophosphate---olivetolic acid geranyltransferase
|
–
|
|
BRENDA:
BR50302
KEGG:
R10176
MetaCyc:
RXN-7853
|
|
|
|
(R)-mevalonate + ATP <=> H+ + (R)-5-phosphomevalonate + ADP
|
2.7.1.36
mevalonate kinase
|
–
|
|
BRENDA:
BR47775
KEGG:
R02245
MetaCyc:
MEVALONATE-KINASE-RXN
SABIO-RK:
2215
|
|
|
|
2,6-dichlorohydroquinone + Cl- + GSSG + H+ <=> 2,3,5-trichlorohydroquinone + glutathione
|
1.21.4.5
tetrachlorohydroquinone reductive dehalogenase
|
–
|
|
BRENDA:
BR52571
KEGG:
R05403
MetaCyc:
TECH2REDHAL-RXN
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->6)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.155
alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase
|
–
|
|
KEGG:
R05991
|
|
|
|
1D-myo-inositol_1,3,4,5-tetrakisphosphate + H2O <=> inositol_1,3,4-trisphosphate + phosphate
|
3.1.3.36
phosphoinositide 5-phosphatase
3.1.3.56
inositol-polyphosphate 5-phosphatase
|
–
–
|
|
BRENDA:
BR48157
KEGG:
R03430
MetaCyc:
RXN-8730
SABIO-RK:
3227
|
|
|
|
ascorbate + O2 + H2O <=> L-threonate + oxalate
|
not assigned
|
–
|
|
KEGG:
R00646
|
|
|
|
FMNH2 + NADP+ <=> FMN + NADPH + H+
|
1.18.1.2
ferredoxin---NADP+ reductase
1.5.1
1.5.1.30
flavin reductase (NADPH)
1.5.1.36
flavin reductase (NADH)
1.5.1.38
FMN reductase (NADPH)
1.5.1.39
FMN reductase [NAD(P)H]
1.5.1.41
riboflavin reductase [NAD(P)H]
1.5.1.42
FMN reductase (NADH)
1.5.1.45
FAD reductase [NAD(P)H]
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR36899
KEGG:
R05706
MetaCyc:
FMNREDUCT-RXN;
RXN-12444
SABIO-RK:
5302
|
|
|
|
(9Z,11E,13S,15Z)-13-hydroperoxy-9,11,15-octadecatrienoate <=> H2O + (9Z)-(13S)-12,13-epoxyoctadeca-9,11,15-trienoate
|
4.2.1.92
hydroperoxide dehydratase
|
–
|
|
BRENDA:
BR48341;
BS363380
KEGG:
R07863
MetaCyc:
RXN1F-19
|
|
|
|
S-adenosyl-L-methionine + cobalt-precorrin-5B <=> cobalt-precorrin-6A + S-adenosyl-L-homocysteine
|
2.1.1.195
cobalt-precorrin-5B (C1)-methyltransferase
|
–
|
|
BRENDA:
BR49385
KEGG:
R07773
MetaCyc:
RXN-8764
|
|
|
|
methanesulfonate + O2 + NADH <=> formaldehyde + sulfite + NAD+ + H2O
|
1.14.13.111
methanesulfonate monooxygenase (NADH)
|
–
|
|
BRENDA:
BR49021
KEGG:
R09513
MetaCyc:
RXN-9770
|
|
|
|
beta-D-glucosyl-N-acylsphingosine + H2O <=> ceramide + D-glucose
|
3.2.1.104
steryl-beta-glucosidase
3.2.1.21
beta-glucosidase
3.2.1.45
glucosylceramidase
3.2.1.62
glycosylceramidase
|
–
–
–
–
|
|
BRENDA:
BR16004;
BS140065
KEGG:
R01498
MetaCyc:
GLUCOSYLCERAMIDASE-RXN
SABIO-RK:
12280
|
|
|
|
ATP + pyridoxamine <=> H+ + ADP + pyridoxamine_5''-phosphate
|
2.7.1.35
pyridoxal kinase
2.7.1.49
hydroxymethylpyrimidine kinase
|
–
–
|
|
BRENDA:
BS357527
KEGG:
R02493
MetaCyc:
PYRAMKIN-RXN
|
|
|
|
2-Oxo-5-methyl-cis-muconate <=> (2E,4Z)-2-hydroxyhexa-2,4-dienoate + CO2
|
4.1.1.77
2-oxo-3-hexenedioate decarboxylase
|
–
|
|
KEGG:
R05374
|
|
|
|
heme + (2E,6E)-farnesyl_diphosphate + H2O <=> heme_O + diphosphate
|
2.5.1.141
heme o synthase
|
–
|
|
BRENDA:
BS427516
KEGG:
R07411
|
|
|
|
geranylgeranyl_diphosphate <=> terpentedienyl_diphosphate
|
5.5.1.15
terpentedienyl-diphosphate synthase
|
–
|
|
BRENDA:
BR48916
KEGG:
R09714
MetaCyc:
RXN-9456
|
|
|
|
Insulin + 2 glutathione <=> reduced_insulin + GSSG
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
|
KEGG:
R02824
|
|
|
|
(S)-2,3,4,5-tetrahydropyridine-2-carboxylate <=> L-pipecolic_acid
|
not assigned
|
–
|
|
KEGG:
R08414
|
|
|
|
5-Oxoavermectin_''''1a''''_aglycone + NADPH + H+ <=> Avermectin_B1a_aglycone + NADP+
|
not assigned
|
–
|
|
KEGG:
R06473
|
|
|
|
copalyl_diphosphate <=> diphosphate + abieta-7,13-diene
|
4.2.3.18
abieta-7,13-diene synthase
|
–
|
|
BRENDA:
BR49933
KEGG:
R06301
MetaCyc:
4.2.3.18-RXN
|
|
|
|
putrescine + 2-oxoglutarate <=> L-glutamate + Aliphatic-Omega-Amino-Aldehydes
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.29
diamine transaminase
2.6.1.82
putrescine---2-oxoglutarate transaminase
|
–
–
–
|
|
BRENDA:
BR47680;
BR48746
KEGG:
R01155;
R07275
MetaCyc:
DIAMTRANSAM-RXN;
PUTTRANSAM-RXN
|
|
|
|
beta-D-fructose_6-phosphate + diphosphate <=> H+ + phosphate + D-fructose_1,6-bisphosphate
|
2.7.1.90
diphosphate---fructose-6-phosphate 1-phosphotransferase
|
–
|
|
BRENDA:
BR47815
KEGG:
R00764;
R02073
MetaCyc:
2.7.1.90-RXN
SABIO-RK:
1119;
14403
|
|
|
|
H+ + alpha-D-glucose_1-phosphate + ATP <=> ADP-glucose + diphosphate
|
2.7.7.24
glucose-1-phosphate thymidylyltransferase
2.7.7.27
glucose-1-phosphate adenylyltransferase
2.7.7.9
UTP---glucose-1-phosphate uridylyltransferase
|
–
–
–
|
|
BRENDA:
BR47873
KEGG:
R00948
MetaCyc:
GLUC1PADENYLTRANS-RXN
SABIO-RK:
1262;
9396
|
|
|
|
S-adenosyl-L-methionine + L-homocysteine <=> L-methionine + S-adenosyl-L-homocysteine + H+
|
2.1.1.10
homocysteine S-methyltransferase
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
2.1.1.280
selenocysteine Se-methyltransferase
|
–
–
–
–
|
|
BRENDA:
BS289526;
BS419713
KEGG:
R00650
MetaCyc:
HOMOCYSTEINE-S-METHYLTRANSFERASE-RXN
SABIO-RK:
1035
|
|
|
|
Fumiquinazoline_A + O2 <=> Fumiquinazoline_C + H2O2
|
1.5.3
|
–
|
|
KEGG:
R12420
MetaCyc:
RXN-15749
|
|
|
|
L-lactate + oxaloacetate <=> pyruvate + (S)-malate
|
1.1.99.7
lactate---malate transhydrogenase
|
–
|
|
BRENDA:
BR29380;
BS451175
KEGG:
R01447
MetaCyc:
LACTATE-MALATE-TRANSHYDROGENASE-RXN
|
|
|
|
8 malonyl-CoA + [acyl-carrier_protein] <=> 3,5,7,9,11,13,15-Heptaoxo-hexadecanoyl-[acp] + 8 CO2 + 8 CoA
|
2.3.1
|
–
|
|
KEGG:
R09258
|
|
|
|
(R)-1-aminopropan-2-ol + NAD+ <=> H+ + aminoacetone + NADH
|
1.1.1.75
(R)-aminopropanol dehydrogenase
|
–
|
|
BRENDA:
BR29336
KEGG:
R03759
MetaCyc:
AMINOPROPDEHYDROG-RXN
|
|
|
|
L-rhamnose + NADP+ <=> L-Rhamno-1,4-lactone + NADPH + H+
|
1.1.1.173
L-rhamnose 1-dehydrogenase
1.1.1.377
L-rhamnose 1-dehydrogenase (NADP+)
1.1.1.378
L-rhamnose 1-dehydrogenase [NAD(P)+]
|
–
–
–
|
|
BRENDA:
BR51099
KEGG:
R10788
|
|
|
|
L-ornithine <=> L-proline + NH3
|
4.3.1.12
ornithine cyclodeaminase
|
–
|
|
BRENDA:
BR3424
KEGG:
R00671
MetaCyc:
ORNITHINE-CYCLODEAMINASE-RXN
SABIO-RK:
1051
|
|
|
|
L-phenylalanine + O2 + H2O <=> phenylpyruvate + NH3 + H2O2 + H+
|
1.13.12.9
phenylalanine 2-monooxygenase
1.4.3.14
L-lysine oxidase
1.4.3.2
L-amino-acid oxidase
|
–
–
–
|
|
BRENDA:
BS258989
KEGG:
R00689
MetaCyc:
RXN-17130
SABIO-RK:
1069
|
|
|
|
glycolaldehyde + 2-oxobutyrate + L-alanine <=> pyridoxine
|
not assigned
|
–
|
|
KEGG:
R05840
|
|
|
|
5,10-methylenetetrahydrofolate + D-alanine + H2O <=> 2-methyl-DL-serine + tetrahydrofolate
|
2.1.2.1
glycine hydroxymethyltransferase
2.1.2.7
D-alanine 2-hydroxymethyltransferase
|
–
–
|
|
BRENDA:
BR43945
KEGG:
R01225
MetaCyc:
D-ALANINE-HYDROXYMETHYLTRANSFERASE-RXN
|
|
|
|
O-Phospho-DL-homoserine + L-selenocysteine <=> L-selenocystathionine + phosphate
|
2.5.1.48
cystathionine gamma-synthase
|
–
|
|
KEGG:
R04944
|
|
|
|
Avermectin_B1b_aglycone + S-adenosyl-L-methionine <=> Avermectin_A1b_aglycone + S-adenosyl-L-homocysteine
|
2.1.1
|
–
|
|
KEGG:
R06479
|
|
|
|
L-Tyrosyl-[pcp] + O2 <=> beta-Hydroxy-L-tyrosyl-[pcp] + H2O
|
not assigned
|
–
|
|
KEGG:
R06752
|
|
|
|
L-lysine + H+ <=> cadaverine + CO2
|
4.1.1.17
ornithine decarboxylase
4.1.1.18
lysine decarboxylase
4.1.1.19
arginine decarboxylase
4.1.1.50
adenosylmethionine decarboxylase
4.1.1.86
diaminobutyrate decarboxylase
4.1.1.B12
|
–
–
–
–
–
–
|
|
BRENDA:
BR6435
KEGG:
R00462
MetaCyc:
LYSDECARBOX-RXN
SABIO-RK:
899
|
|
|
|
amylose + phosphate <=> amylose + alpha-D-glucose_1-phosphate
|
2.4.1.1
glycogen phosphorylase
|
–
|
|
BRENDA:
BR44131;
BS321850;
BS321851;
BS321852;
BS389786
KEGG:
R01821;
R02111;
R06050;
R06185
MetaCyc:
RXN-12171;
RXN0-5184
SABIO-RK:
2101
|
|
|
|
D-ornithine <=> bacitracin
|
not assigned
|
–
|
|
KEGG:
R02460
|
|
|
|
4alpha-methyl-5alpha-ergosta-8,24-dien-3beta-ol + NADP+ <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + NADPH + H+
|
1.3.1.70
Delta14-sterol reductase
|
–
|
|
BRENDA:
BS370809
KEGG:
R07483
MetaCyc:
RXN-4144
|
|
|
|
H2O + dGTP <=> H+ + tripolyphosphate + 2''-deoxyguanosine
|
3.1.5.1
dGTPase
|
–
|
|
BRENDA:
BR15965
KEGG:
R01856
MetaCyc:
DGTPTRIPHYDRO-RXN
SABIO-RK:
232
|
|
|
|
H2O + beta-D-fructose_2,6-bisphosphate <=> phosphate + beta-D-fructose_6-phosphate
|
3.1.3.25
inositol-phosphate phosphatase
3.1.3.46
fructose-2,6-bisphosphate 2-phosphatase
|
–
–
|
|
BRENDA:
BR11746;
BS364538
KEGG:
R00763;
R02731
MetaCyc:
3.1.3.46-RXN
SABIO-RK:
1118;
27;
6734
|
|
|
|
D-2,5-diaminohexanoate + H2O + NAD+ <=> 2-Amino-5-oxohexanoate + NH3 + NADH + H+
|
1.4.1.12
2,4-diaminopentanoate dehydrogenase
|
–
|
|
KEGG:
R04687
|
|
|
|
(3S,5S)-carbapenam_3-carboxylate + 2-oxoglutarate + O2 <=> (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O
|
1.14.20
1.14.20.3
(5R)-carbapenem-3-carboxylate synthase
|
–
–
|
|
BRENDA:
BR50588
KEGG:
R10415
MetaCyc:
RXN-8949
|
|
|
|
(2E,6E)-farnesyl_diphosphate + H2O <=> (3R,6E)-nerolidol + diphosphate
|
4.2.3.25
S-linalool synthase
4.2.3.26
R-linalool synthase
4.2.3.48
(3S,6E)-nerolidol synthase
4.2.3.49
(3R,6E)-nerolidol synthase
|
–
–
–
–
|
|
BRENDA:
BR49344;
BR49345
KEGG:
R08374;
R09618
MetaCyc:
RXN-11575;
RXN-8616
SABIO-RK:
14620
|
|
|
|
alpha-D-sedoheptulopyranose_7-phosphate <=> 2-epi-5-epi-valiolone + phosphate
|
4.2.3.152
2-epi-5-epi-valiolone synthase
|
–
|
|
BRENDA:
BR51246
KEGG:
R10937
MetaCyc:
RXN-9140
|
|
|
|
(10aS)-10,10a-dihydrophenazine-1-carboxylate <=> 5,10-dihydrophenazine_1-carboxylate
|
not assigned
|
–
|
|
KEGG:
R11576
MetaCyc:
RXN-17691
|
|
|
|
7,8-dihydroneopterin_3''-triphosphate <=> 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde_triphosphate
|
4.1.2.60
dihydroneopterin triphosphate aldolase
|
–
|
|
BRENDA:
BR52078
KEGG:
R11719
MetaCyc:
RXN-18377
|
|
|
|
1-hydroxylycopene + acceptor <=> 1-hydroxy-3,4-didehydrolycopene + reduced_acceptor
|
1.3.99.27
1-hydroxycarotenoid 3,4-desaturase
1.3.99.30
phytoene desaturase (3,4-didehydrolycopene-forming)
1.3.99.37
1-hydroxy-2-isopentenylcarotenoid 3,4-desaturase
|
–
–
–
|
|
BRENDA:
BR49672
KEGG:
R07520
MetaCyc:
RXN-11647
|
|
|
|
xylitol + NAD+ <=> D-xylose + NADH + H+
|
1.1.1.21
aldose reductase
1.1.1.307
D-xylose reductase
|
–
–
|
|
BRENDA:
BR49151
KEGG:
R09477
MetaCyc:
RXN-11315_WOP
SABIO-RK:
6501
|
|
|
|
GDP-4-dehydro-6-deoxy-D-mannose + L-glutamate <=> GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + 2-oxoglutarate + NH3
|
4.2.1.168
GDP-4-dehydro-6-deoxy-alpha-D-mannose 3-dehydratase
|
–
|
|
BRENDA:
BR51779
KEGG:
R11409
MetaCyc:
RXN-17514
|
|
|
|
3-fumarylpyruvate + H2O <=> H+ + fumarate + pyruvate
|
3.7.1
3.7.1.20
3-fumarylpyruvate hydrolase
3.7.1.5
acylpyruvate hydrolase
4.1.1.112
oxaloacetate decarboxylase
|
–
–
–
–
|
|
BRENDA:
BR50325
KEGG:
R01085
MetaCyc:
RXN-10445;
RXN-13372
|
|
|
|
chorismate <=> 4-hydroxybenzoate + pyruvate
|
4.1.3.40
chorismate lyase
|
–
|
|
BRENDA:
BR48792
KEGG:
R01302
MetaCyc:
CHORPYRLY-RXN
|
|
|
|
D-mannitol + NADP+ <=> D-fructose + NADPH + H+
|
1.1.1.138
mannitol 2-dehydrogenase (NADP+)
1.1.1.14
L-iditol 2-dehydrogenase
1.1.1.21
aldose reductase
1.1.1.287
D-arabinitol dehydrogenase (NADP+)
1.1.1.289
sorbose reductase
1.1.1.67
mannitol 2-dehydrogenase
|
–
–
–
–
–
–
|
|
BRENDA:
BR29204
KEGG:
R00870
SABIO-RK:
1201;
6524
|
|
|
|
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine + H2O <=> UDP-3-O-((3R)-3-hydroxymyristoyl)-alpha-D-glucosamine + acetate
|
3.5.1.108
UDP-3-O-acyl-N-acetylglucosamine deacetylase
|
–
|
|
BRENDA:
BR49202
KEGG:
R04587
MetaCyc:
UDPACYLGLCNACDEACETYL-RXN
|
|
|
|
valienone_7-phosphate <=> validone_7-phosphate
|
not assigned
|
–
|
|
KEGG:
R11236
|
|
|
|
lycopene <=> delta-carotene
|
5.5.1.18
lycopene epsilon-cyclase
|
–
|
|
BRENDA:
BS415670
KEGG:
R06963
MetaCyc:
RXN1F-147
|
|
|
|
H+ + 3-dehydro-L-gulonate <=> L-xylulose + CO2
|
4.1.1.34
dehydro-L-gulonate decarboxylase
|
–
|
|
BRENDA:
BR293
KEGG:
R01905
MetaCyc:
DEHYDRO-L-GULONATE-DECARBOXYLASE-RXN
|
|
|
|
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate <=> (S)-allantoin + CO2
|
4.1.1.97
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase
|
–
|
|
BRENDA:
BR50998
KEGG:
R06604
|
|
|
|
(S)-3-hydroxy-3-methylglutaryl-CoA <=> acetoacetate + acetyl-CoA
|
4.1.3.4
hydroxymethylglutaryl-CoA lyase
|
–
|
|
BRENDA:
BR395;
BS416230
KEGG:
R01360
MetaCyc:
HYDROXYMETHYLGLUTARYL-COA-LYASE-RXN
SABIO-RK:
1564
|
|
|
|
(S)-8-oxocitronellyl_enol + NAD+ <=> (6E)-8-oxogeranial + NADH + H+
|
1.3.1.122
(S)-8-oxocitronellyl enol synthase
|
–
|
|
BRENDA:
BR52966-a
KEGG:
R12517
MetaCyc:
RXN-20745_WOP
|
|
|
|
Gibberellin_A53 + O2 + 2-oxoglutarate <=> gibberellin_44 + CO2 + succinate
|
1.14.11
1.14.11.12
gibberellin-44 dioxygenase
|
–
–
|
|
KEGG:
R05097
MetaCyc:
RXN1F-167
SABIO-RK:
4719
|
|
|
|
1,4-androstadiene-3,17-dione + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> 9alpha-hydroxy-1,4-androstadiene_3,17-dione + oxidized_ferredoxin + H2O
|
1.14.15.30
3-ketosteroid 9alpha-monooxygenase
|
–
|
|
BRENDA:
BR49974
KEGG:
R09860
MetaCyc:
RXN-12691
|
|
|
|
Glycerophosphoglycoglycerolipid <=> lipoteichoic_acid
|
not assigned
|
–
|
|
KEGG:
R10863
|
|
|
|
gamma-glutamyl-gamma-aminobutyraldehyde + NADP+ + H2O <=> 4-(glutamylamino)_butanoate + NADPH + H+
|
1.2.1.99
4-(gamma-glutamylamino)butanal dehydrogenase
|
–
|
|
BRENDA:
BR49659
KEGG:
R07418
MetaCyc:
RXN0-3922
|
|
|
|
fumitremorgin_C + 2 reduced_flavodoxin + 2 O2 <=> 12alpha,13alpha-dihydroxyfumitremorgin_C + 2 flavin + 2 H2O
|
1.14.14.119
fumitremorgin C monooxygenase
|
–
|
|
BRENDA:
BR50576
KEGG:
R10414
|
|
|
|
glycine + gamma-Glu-2-aminobutyrate + ATP <=> ophthalmate + ADP + phosphate + H+
|
6.3.2.3
glutathione synthase
|
–
|
|
BRENDA:
BS567
KEGG:
R10994
MetaCyc:
RXN-20401
SABIO-RK:
10482
|
|
|
|
H+ + DELTA1-piperideine-2-carboxylate + H2O <=> 6-Amino-2-oxohexanoate
|
not assigned
|
–
|
|
KEGG:
R04175
MetaCyc:
RXN-8172
|
|
|
|
H2O + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide <=> N-acetyl-D-galactosamine + globotriaosylceramide
|
3.2.1.52
beta-N-acetylhexosaminidase
|
–
|
|
KEGG:
R05963
|
|
|
|
ITP + H2O <=> IDP + phosphate + H+
|
3.1.3.2
acid phosphatase
3.1.3.5
5'-nucleotidase
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.28
thiamine-triphosphatase
3.6.1.3
adenosinetriphosphatase
3.6.1.5
apyrase
3.6.1.6
nucleoside diphosphate phosphatase
3.6.1.62
5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase
3.6.1.64
inosine diphosphate phosphatase
3.6.1.66
XTP/dITP diphosphatase
3.6.1.73
inosine/xanthosine triphosphatase
3.6.1.9
nucleotide diphosphatase
3.6.4.13
RNA helicase
3.6.5.3
protein-synthesizing GTPase
3.6.5.6
tubulin GTPase
7.1.2.1
P-type H+-exporting transporter
7.1.2.2
H+-transporting two-sector ATPase
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR53049
KEGG:
R00719
MetaCyc:
RXN0-5073
SABIO-RK:
1090
|
|
|
|
argininosuccinate <=> L-arginine + fumarate
|
4.3.2.1
argininosuccinate lyase
4.3.2.2
adenylosuccinate lyase
|
–
–
|
|
BRENDA:
BR3431
KEGG:
R01086
MetaCyc:
ARGSUCCINLYA-RXN
SABIO-RK:
573
|
|
|
|
1-hydroxy-2-naphthaldehyde + NAD+ + H2O <=> 1-hydroxy-2-naphthoate + NADH + H+
|
1.2.1
|
–
|
|
KEGG:
R05649
|
|
|
|
4-coumaroyl-CoA + putrescine <=> CoA + N-coumaroylputrescine
|
2.3.1
2.3.1.138
putrescine N-hydroxycinnamoyltransferase
2.3.1.64
agmatine N4-coumaroyltransferase
|
–
–
–
|
|
BRENDA:
BS320494
KEGG:
R09256
|
|
|
|
2''-deoxyadenosine + phosphate <=> adenine + 2-deoxy-alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
|
–
–
|
|
BRENDA:
BS323171;
BS395330
KEGG:
R02557
MetaCyc:
DEOXYADENPHOSPHOR-RXN
SABIO-RK:
342
|
|
|
|
acetone + O2 + NADPH + H+ <=> methyl_acetate + NADP+ + H2O
|
1.14.13.226
acetone monooxygenase (methyl acetate-forming)
|
–
|
|
BRENDA:
BR51741
KEGG:
R10704
MetaCyc:
RXN-17567
|
|
|
|
dihydrokaempferol + reduced_flavodoxin + O2 <=> dihydroquercetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
|
BRENDA:
BS288544
KEGG:
R03124
|
|
|
|
(5S,6S)-6-amino-5-hydroxycyclohexa-1,3-diene-1-carboxylic_acid <=> (1R,6S)-6-amino-5-oxocyclohex-2-ene-1-carboxylate
|
5.3.3.17
trans-2,3-dihydro-3-hydroxyanthranilate isomerase
|
–
|
|
BRENDA:
BR49351
KEGG:
R09707
MetaCyc:
RXN-9031
|
|
|
|
5-epi-valiolone <=> valienone + H2O
|
4.2.1
|
–
|
|
KEGG:
R11233
MetaCyc:
RXN-9142
|
|
|
|
pregnenolone + reduced_flavodoxin + O2 <=> 17alpha-hydroxypregnenolone + flavin + H2O
|
1.14.14.19
steroid 17alpha-monooxygenase
1.14.14.32
17alpha-hydroxyprogesterone deacetylase
|
–
–
|
|
BRENDA:
BS427508
KEGG:
R03783
|
|
|
|
H+ + molybdopterin + ATP <=> adenylyl-molybdopterin + diphosphate
|
2.7.7.75
molybdopterin adenylyltransferase
|
–
|
|
BRENDA:
BR49475
KEGG:
R09726
MetaCyc:
RXN-8344
|
|
|
|
H+ + H2O + adenine <=> NH3 + hypoxanthine
|
3.5.4.2
adenine deaminase
|
–
|
|
BRENDA:
BR19264
KEGG:
R01244
MetaCyc:
ADENINE-DEAMINASE-RXN
SABIO-RK:
131
|
|
|
|
scyllo-Inositol + NADP+ <=> scyllo-inosose + NADPH + H+
|
1.1.1
1.1.1.371
scyllo-inositol 2-dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BR50932
KEGG:
R09954
MetaCyc:
RXN-14347
|
|
|
|
beta-D-ribosylnicotinamide + ATP <=> H+ + NMN + ADP
|
2.7.1.173
nicotinate riboside kinase
2.7.1.22
ribosylnicotinamide kinase
|
–
–
|
|
BRENDA:
BR47762
KEGG:
R02324
MetaCyc:
RIBOSYLNICOTINAMIDE-KINASE-RXN
SABIO-RK:
2280
|
|
|
|
L-methionine + 2-oxoglutarate <=> 4-methylsulfanyl-2-oxobutanoate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.2
alanine transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.6
leucine transaminase
2.6.1.7
kynurenine---oxoglutarate transaminase
2.6.1.73
methionine---glyoxylate transaminase
2.6.1.88
methionine transaminase
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS353528
KEGG:
R07396
MetaCyc:
RXN-14147
|
|
|
|
phosphocholine + H2O <=> choline + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.75
phosphoethanolamine/phosphocholine phosphatase
3.1.6.6
choline-sulfatase
|
–
–
–
–
|
|
BRENDA:
BR48526
KEGG:
R06871
MetaCyc:
RXN-5647
SABIO-RK:
6446
|
|
|
|
beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + H2O <=> chondroitin_4-sulfate + N-acetyl-D-galactosamine
|
3.2.1.35
hyaluronoglucosaminidase
|
–
|
|
KEGG:
R07824
|
|
|
|
acetyl-CoA + 2-hydroxyglutarate <=> acetate + (R)-2-hydroxyglutaryl-1-CoA
|
2.8.3.12
glutaconate CoA-transferase
|
–
|
|
KEGG:
R04000
|
|
|
|
ATP + pyridoxine <=> H+ + ADP + pyridoxine_5''-phosphate
|
2.7.1.35
pyridoxal kinase
2.7.1.49
hydroxymethylpyrimidine kinase
|
–
–
|
|
BRENDA:
BS357525
KEGG:
R01909
MetaCyc:
PNKIN-RXN
SABIO-RK:
1963
|
|
|
|
L-galactonate + NAD+ <=> D-tagaturonate + NADH + H+
|
1.1.1.414
L-galactonate 5-dehydrogenase
|
–
|
|
BRENDA:
BR52085
KEGG:
R12146
MetaCyc:
RXN0-5229
|
|
|
|
versiconal_hemiacetal_acetate + H2O <=> versiconal + acetate
|
3.1.1.94
versiconal hemiacetal acetate esterase
|
–
|
|
BRENDA:
BR50545
KEGG:
R10401
MetaCyc:
RXN-9488
|
|
|
|
linamarin + H2O <=> acetone_cyanohydrin + D-glucose
|
3.2.1.117
amygdalin beta-glucosidase
3.2.1.21
beta-glucosidase
|
–
–
|
|
BRENDA:
BS361131
KEGG:
R10040
MetaCyc:
RXN-5341
|
|
|
|
reduced_ferredoxin_[iron-sulfur]_cluster + N2 + ATP + H2O <=> oxidized_ferredoxin + H2 + NH3 + ADP + phosphate + H+
|
1.18.6.1
nitrogenase
1.18.6.2
vanadium-dependent nitrogenase
1.19.6.1
nitrogenase (flavodoxin)
|
–
–
–
|
|
BRENDA:
BR40514
KEGG:
R05185;
R12084
MetaCyc:
NITROGENASE-RXN;
RXN-19345
|
|
|
|
violaxanthin <=> neoxanthin
|
5.3.99.9
neoxanthin synthase
|
–
|
|
BRENDA:
BR48546
KEGG:
R06948
MetaCyc:
RXN1F-155
|
|
|
|
S-formylglutathione + H2O <=> H+ + formate + glutathione
|
3.1.1.56
methylumbelliferyl-acetate deacetylase
3.1.2.12
S-formylglutathione hydrolase
3.1.2.6
hydroxyacylglutathione hydrolase
|
–
–
–
|
|
BRENDA:
BR10672
KEGG:
R00527
MetaCyc:
S-FORMYLGLUTATHIONE-HYDROLASE-RXN
SABIO-RK:
945
|
|
|
|
abieta-7,13-diene + reduced_flavodoxin + O2 <=> abietadienol + flavin + H2O
|
1.14.14.144
abieta-7,13-diene hydroxylase
|
–
|
|
BRENDA:
BR49044
KEGG:
R06351
|
|
|
|
S-adenosyl-L-methionine + cobalt-precorrin-4 <=> S-adenosyl-L-homocysteine + cobalt-precorrin-5A + H+
|
2.1.1.271
cobalt-precorrin-4 methyltransferase
|
–
|
|
BRENDA:
BR50534
KEGG:
R05810
MetaCyc:
RXN-8762
|
|
|
|
UDP-glucose + amylose <=> UDP + starch
|
2.4.1.11
glycogen(starch) synthase
2.4.1.21
starch synthase (glycosyl-transferring)
2.4.1.242
NDP-glucose---starch glucosyltransferase
|
–
–
–
|
|
BRENDA:
BR44139;
BS321969;
BS410567
KEGG:
R00292;
R06051
|
|
|
|
quinate + NAD+ <=> 3-dehydroquinate + NADH + H+
|
1.1.1.166
hydroxycyclohexanecarboxylate dehydrogenase
1.1.1.24
quinate dehydrogenase
1.1.1.25
shikimate dehydrogenase
1.1.1.282
quinate/shikimate dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BR29276
KEGG:
R01872
MetaCyc:
QUINATE-5-DEHYDROGENASE-RXN_WOP;
RXN-20483
SABIO-RK:
12025;
1936
|
|
|
|
L-allo-threonine <=> glycine + acetaldehyde
|
2.1.2.1
glycine hydroxymethyltransferase
4.1.2
4.1.2.26
phenylserine aldolase
4.1.2.48
low-specificity L-threonine aldolase
4.1.2.49
L-allo-threonine aldolase
4.1.3.14
L-erythro-3-hydroxyaspartate aldolase
|
–
–
–
–
–
–
|
|
BRENDA:
BR49772;
BS1838
KEGG:
R06171
MetaCyc:
LTAA-RXN;
RXN0-5234
SABIO-RK:
5754
|
|
|
|
N-methylmyosmine + H2O <=> 4-(methylamino)-1-(pyridin-3-yl)butan-1-one
|
1.5.3
|
–
|
|
KEGG:
R11176
MetaCyc:
RXN-13077
|
|
|
|
taxifolin + 2-oxoglutarate + O2 <=> quercetin + succinate + CO2 + H2O
|
1.14.20.4
anthocyanidin synthase
1.14.20.6
flavonol synthase
|
–
–
|
|
BRENDA:
BS371257;
BS373099
KEGG:
R02160
MetaCyc:
RXN-527
SABIO-RK:
2139
|
|
|
|
N-(5-phospho-beta-D-ribosyl)anthranilate <=> 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate
|
5.3.1.24
phosphoribosylanthranilate isomerase
|
–
|
|
BRENDA:
BR48377
KEGG:
R03509
MetaCyc:
PRAISOM-RXN
SABIO-RK:
15372
|
|
|
|
vitamin_D3 + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> 25-hydroxyvitamin_D3 + oxidized_ferredoxin + H2O
|
1.14.15.22
vitamin D 1,25-hydroxylase
|
–
|
|
BRENDA:
BR51834
KEGG:
R11458
MetaCyc:
RXN-18214
|
|
|
|
UDP-glucose + quercetin <=> UDP + quercetin_3-O-glucoside + H+
|
2.4.1.115
anthocyanidin 3-O-glucosyltransferase
2.4.1.177
cinnamate beta-D-glucosyltransferase
2.4.1.35
phenol beta-glucosyltransferase
2.4.1.357
phlorizin synthase
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
–
–
–
–
|
|
BRENDA:
BS323087;
BS445961
KEGG:
R02158
MetaCyc:
RXN1F-462
SABIO-RK:
13061
|
|
|
|
2-sulfoacetaldehyde <=> coenzyme_M
|
not assigned
|
–
|
|
KEGG:
R09153
|
|
|
|
L-threo-tetrahydrobiopterin + 2 NADP+ <=> 6-pyruvoyltetrahydropterin + 2 NADPH + 2 H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325
sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
|
–
–
|
|
BRENDA:
BR50020
KEGG:
R09990
|
|
|
|
2-dehydro-D-gluconate + ATP <=> H+ + 6-phospho-2-dehydro-D-gluconate + ADP
|
2.7.1.13
dehydrogluconokinase
2.7.1.45
2-dehydro-3-deoxygluconokinase
|
–
–
|
|
BRENDA:
BR47742
KEGG:
R02658
MetaCyc:
DEHYDOGLUCONOKINASE-RXN
|
|
|
|
2,4-Diaminopentanoate + H2O + NAD+ <=> (2R)-2-amino-4-oxopentanoate + NH3 + NADH + H+
|
1.4.1.12
2,4-diaminopentanoate dehydrogenase
1.4.1.26
2,4-diaminopentanoate dehydrogenase (NAD+)
|
–
–
|
|
BRENDA:
BR36860-a;
BS258906-a
KEGG:
R04200
MetaCyc:
24-DIAMINOPENTANOATE-DEHYDROGENASE-RXN_WOP;
RXN-18499
|
|
|
|
3-phospho-D-glycerate + H+ <=> D-ribulose_1,5-bisphosphate + CO2 + H2O
|
4.1.1.39
ribulose-bisphosphate carboxylase
|
–
|
|
BRENDA:
BR297
KEGG:
R00024
MetaCyc:
RIBULOSE-BISPHOSPHATE-CARBOXYLASE-RXN
SABIO-RK:
9130
|
|
|
|
diacylglycerol + Phospholipid <=> triacylglycerol + Lysophospholipid
|
2.3.1.158
phospholipid:diacylglycerol acyltransferase
|
–
|
|
BRENDA:
BR36936
KEGG:
R05333
MetaCyc:
2.3.1.158-RXN
|
|
|
|
isethionate + 2 ferricytochrome_c <=> 2-sulfoacetaldehyde + 2 ferricytochrome_c + 2 H+
|
1.1.2
|
–
|
|
KEGG:
R06981
|
|
|
|
5-Dehydro-L-gluconate <=> D-tagaturonate
|
5.1
5.3.3
|
–
–
|
|
KEGG:
R11772
MetaCyc:
RXN-14360
|
|
|
|
3''-phosphoadenylyl-sulfate + desulfo-indol-3-yl-methyl_glucosinolate <=> adenosine_3,5''-bisphosphate + glucobrassicin + H+
|
2.8.2.24
aromatic desulfoglucosinolate sulfotransferase
2.8.2.38
aliphatic desulfoglucosinolate sulfotransferase
|
–
–
|
|
BRENDA:
BR52177;
BS407937
KEGG:
R08167
MetaCyc:
RXN-1443
|
|
|
|
L-aspartate + 2-oxoglutarate <=> oxaloacetate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.75
cysteine-conjugate transaminase
2.6.1.78
aspartate---prephenate aminotransferase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR47671;
BS377429
KEGG:
R00355
MetaCyc:
ASPAMINOTRANS-RXN;
RXN-13697
SABIO-RK:
825
|
|
|
|
L-aspartate + L-citrulline + ATP <=> H+ + argininosuccinate + diphosphate + AMP
|
6.3.4.5
argininosuccinate synthase
|
–
|
|
BRENDA:
BR142;
BS408483
KEGG:
R01954
MetaCyc:
ARGSUCCINSYN-RXN
SABIO-RK:
572
|
|
|
|
phosphatidylethanolamine + L-serine <=> phosphatidylserine + ethanolamine
|
2.7.8.29
L-serine-phosphatidylethanolamine phosphatidyltransferase
|
–
|
|
BRENDA:
BR49243
KEGG:
R07376
MetaCyc:
RXN-1382
|
|
|
|
L-dihydroorotate + NAD+ <=> H+ + Orotate + NADH
|
1.3.1.14
dihydroorotate dehydrogenase (NAD+)
|
–
|
|
BRENDA:
BR36799
KEGG:
R01869
MetaCyc:
OROTATE-REDUCTASE-NADH-RXN
SABIO-RK:
486
|
|
|
|
L-fucose <=> L-Fuculose
|
5.3.1.25
L-fucose isomerase
5.3.1.3
D-arabinose isomerase
5.3.1.4
L-arabinose isomerase
|
–
–
–
|
|
BRENDA:
BR232
KEGG:
R03163
MetaCyc:
FUCISOM-RXN
SABIO-RK:
2993
|
|
|
|
L-glutamate + UDP-N-acetylmuramoyl-L-Ala + ATP <=> UDP-MurNAc-L-Ala-L-Glu + phosphate + ADP + H+
|
6.3.2.53
UDP-N-acetylmuramoyl-L-alanine---L-glutamate ligase
|
–
|
|
BRENDA:
BR52619
KEGG:
R12272
MetaCyc:
RXN-19251
|
|
|
|
Phthalate + O2 + NADH + H+ <=> cis-4,5-dihydroxycyclohexa-1(6),2-diene-1,2-dicarboxylate + NAD+
|
1.14.12.7
phthalate 4,5-dioxygenase
|
–
|
|
BRENDA:
BR40440
KEGG:
R03630
MetaCyc:
PHTHALATE-45-DIOXYGENASE-RXN
|
|
|
|
butyryl-CoA + acetyl-CoA <=> 3-oxohexanoyl-CoA + CoA
|
2.3.1.155
acetyl-CoA C-myristoyltransferase
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.9
acetyl-CoA C-acetyltransferase
|
–
–
–
|
|
BRENDA:
BS189544
KEGG:
R01177
MetaCyc:
RXN-12565
SABIO-RK:
1414
|
|
|
|
(+)-dihydrokaempferol + 2-oxoglutarate + O2 <=> kaempferol + succinate + CO2 + H2O + H+
|
1.14.20.5
flavone synthase I
1.14.20.6
flavonol synthase
|
–
–
|
|
BRENDA:
BS371221;
BS373078
KEGG:
R03126
MetaCyc:
RXN1F-93
|
|
|
|
UDP-N-acetyl-D-galactosamine + Type_IIIH_glycolipid <=> UDP + Type_IIIA_glycolipid
|
2.4.1.40
glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase
|
–
|
|
KEGG:
R06197
|
|
|
|
gamma-glutamyltyramine + [5-(aminomethyl)furan-3-yl]methyl_diphosphate <=> (4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine + diphosphate
|
2.5.1.131
(4-{4-[2-(gamma-L-glutamylamino)ethyl]phenoxymethyl}furan-2-yl)methanamine synthase
|
–
|
|
BRENDA:
BR51529
KEGG:
R11040
MetaCyc:
RXN-15945
|
|
|
|
NADP+ + codeine <=> H+ + NADPH + codeinone
|
1.1.1.218
morphine 6-dehydrogenase
1.1.1.247
codeinone reductase (NADPH)
|
–
–
|
|
BRENDA:
BR916
KEGG:
R05124
MetaCyc:
1.1.1.247-RXN
SABIO-RK:
4745
|
|
|
|
ATP + alpha,omega-dicarboxylate + CoA <=> malonyl-CoA + AMP + diphosphate
|
6.2.1
6.2.1.23
dicarboxylate---CoA ligase
|
–
–
|
|
BRENDA:
BR75
KEGG:
R04157;
R12300
MetaCyc:
DICARBOXYLATE--COA-LIGASE-RXN;
RXN-12359
|
|
|
|
7-Mercaptoheptanoylthreonine + ATP <=> H+ + coenzyme_B + ADP
|
2.7.1
|
–
|
|
KEGG:
R08217
MetaCyc:
R227-RXN
|
|
|
|
(R)-reticuline + reduced_flavodoxin + O2 <=> salutaridine + flavin + 2 H2O
|
1.14.19.67
salutaridine synthase
|
–
|
|
BRENDA:
BR36966
KEGG:
R04696
|
|
|
|
D-galacturonate + NADPH + H+ <=> L-galactonate + NADP+
|
1.1.1
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.203
uronate dehydrogenase
1.1.1.21
aldose reductase
1.1.1.365
D-galacturonate reductase
|
–
–
–
–
–
|
|
BRENDA:
BS424745
KEGG:
R07676
SABIO-RK:
10012
|
|
|
|
choloyl-CoA + H2O <=> H+ + cholic_acid + CoA
|
2.8.3.25
bile acid CoA-transferase
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
3.1.2.27
choloyl-CoA hydrolase
|
–
–
–
–
|
|
BRENDA:
BR48553
KEGG:
R07296
MetaCyc:
3.1.2.27-RXN
SABIO-RK:
8638
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> gamma-humulene + diphosphate
|
4.2.3.56
gamma-humulene synthase
|
–
|
|
BRENDA:
BR49427
KEGG:
R08540
MetaCyc:
RXN-8541
|
|
|
|
pentalenolactone_D + 2-oxoglutarate + O2 <=> pentalenolactone_F + succinate + CO2 + H2O
|
1.14.11.36
pentalenolactone F synthase
|
–
|
|
BRENDA:
BR50258
KEGG:
R10145
MetaCyc:
RXN-13751
|
|
|
|
H2O + UDP-2,3-bis((3R)-3-hydroxymyristoyl)-alpha-D-glucosamine <=> H+ + lipid_X_(E._coli) + UMP
|
3.6.1.54
UDP-2,3-diacylglucosamine diphosphatase
|
–
|
|
BRENDA:
BR49205
KEGG:
R04549
MetaCyc:
LIPIDXSYNTHESIS-RXN
|
|
|
|
5 ATP + 3 L-4-hydroxyphenylglycine + L-arginine + L-serine + H2O <=> 5 AMP + 5 diphosphate + nocardicin_G + L-4-Hydroxyphenylglycyl-L-arginine
|
not assigned
|
–
|
|
KEGG:
R10880
|
|
|
|
siroheme + H+ <=> 12,18-didecarboxysiroheme + CO2
|
4.1.1.111
siroheme decarboxylase
|
–
|
|
BRENDA:
BR51140
KEGG:
R12000
MetaCyc:
RXN-15805
|
|
|
|
2-xylene + O2 + 2 reduced_ferredoxin_[iron-sulfur]_cluster + 2 H+ <=> 2-Methylbenzyl_alcohol + 2 oxidized_ferredoxin + H2O
|
1.14.15.26
toluene methyl-monooxygenase
|
–
|
|
BRENDA:
BS443800
KEGG:
R05442
|
|
|
|
L-glutamate + tyramine + ATP <=> gamma-glutamyltyramine + ADP + phosphate + H+
|
6.3.4.24
tyramine---L-glutamate ligase
|
–
|
|
BRENDA:
BR51200
KEGG:
R10902
MetaCyc:
RXN-15947
|
|
|
|
H2O + L-arabinono-1,4-lactone <=> H+ + L-arabinonate
|
3.1.1.15
L-arabinonolactonase
3.1.1.68
xylono-1,4-lactonase
|
–
–
|
|
BRENDA:
BR10646
KEGG:
R02526
MetaCyc:
L-ARABINONOLACTONASE-RXN
|
|
|
|
ethanol + 2 ferricytochrome_b5 <=> acetaldehyde + 2 ferricytochrome_b5
|
1.1.2.7
methanol dehydrogenase (cytochrome c)
|
–
|
|
BRENDA:
BS449899
KEGG:
R09127
|
|
|
|
1,2-propanediol <=> propionaldehyde + H2O
|
4.2.1.28
propanediol dehydratase
4.2.1.30
glycerol dehydratase
|
–
–
|
|
BRENDA:
BR409
KEGG:
R02376
|
|
|
|
cyclooctat-9-ene-5,7-diol + O2 + reduced_acceptor <=> cyclooctatin + H2O + acceptor
|
1.14.99.62
cyclooctatin synthase
|
–
|
|
BRENDA:
BR52475
KEGG:
R12178
MetaCyc:
RXN-15430
|
|
|
|
palmitoyl-[acyl-carrier_protein] + NADP+ <=> trans-Hexadec-2-enoyl-[acp] + NADPH + H+
|
1.3.1
1.3.1.10
enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)
1.3.1.104
enoyl-[acyl-carrier-protein] reductase (NADPH)
1.3.1.39
enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
–
–
–
–
|
|
KEGG:
R04970
MetaCyc:
RXN-9542
|
|
|
|
raffinose + H2O <=> D-galactose + sucrose
|
3.2.1
3.2.1.22
alpha-galactosidase
|
–
–
|
|
BRENDA:
BR19209;
BS115543
KEGG:
R01103;
R06070
MetaCyc:
RXN-11502
SABIO-RK:
1364
|
|
|
|
2-dehydro-3-deoxy-D-gluconate + NAD+ <=> (4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADH + H+
|
1.1.1.125
2-deoxy-D-gluconate 3-dehydrogenase
1.1.1.127
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
|
–
–
|
|
BRENDA:
BR29193
KEGG:
R01542
MetaCyc:
1.1.1.127-RXN
|
|
|
|
uridine + H2O <=> D-ribose + Uracil
|
3.2.2.1
purine nucleosidase
3.2.2.3
uridine nucleosidase
3.2.2.7
adenosine nucleosidase
3.2.2.8
ribosylpyrimidine nucleosidase
|
–
–
–
–
|
|
BRENDA:
BR32612
KEGG:
R01080
MetaCyc:
URIDINE-NUCLEOSIDASE-RXN
SABIO-RK:
472
|
|
|
|
L-glutamine <=> D-glutamine
|
5.1.1.10
amino-acid racemase
5.1.1.18
serine racemase
|
–
–
|
|
BRENDA:
BS392373
KEGG:
R00579
MetaCyc:
RXN1G01-46
|
|
|
|
sulfur + H2O + O2 <=> Sulfide + sulfite + H+
|
1.13.11.55
sulfur oxygenase/reductase
|
–
|
|
BRENDA:
BR48661
KEGG:
R07365
MetaCyc:
1.13.11.55-RXN
|
|
|
|
L-arabitol + NAD+ <=> L-ribulose + NADH + H+
|
1.1.1.13
L-arabinitol 2-dehydrogenase
1.1.1.14
L-iditol 2-dehydrogenase
1.1.1.16
galactitol 2-dehydrogenase
|
–
–
–
|
|
BRENDA:
BR29196
KEGG:
R02441
MetaCyc:
1.1.1.13-RXN
SABIO-RK:
2375
|
|
|
|
H+ + H2O + Beta-cyanoalanine <=> NH3 + L-aspartate
|
3.5.5.4
cyanoalanine nitrilase
|
–
|
|
BRENDA:
BR48303
KEGG:
R00486
MetaCyc:
3.5.5.4-RXN
SABIO-RK:
918
|
|
|
|
octanoyl-[acyl-carrier_protein] + NAD+ <=> 2-octenoyl-[acyl-carrier_protein] + NADH + H+
|
1.3.1.9
enoyl-[acyl-carrier-protein] reductase (NADH)
2.3.1
|
–
–
|
|
BRENDA:
BS258652
KEGG:
R04958
MetaCyc:
RXN-9659
|
|
|
|
(R)-2-hydroxyglutaryl-1-CoA <=> H2O + glutaconyl-CoA
|
4.2.1
4.2.1.167
(R)-2-hydroxyglutaryl-CoA dehydratase
|
–
–
|
|
BRENDA:
BR51549
KEGG:
R03937
MetaCyc:
RXN-1083
|
|
|
|
sucrose + inulin <=> D-glucose + inulin
|
2.4.1.9
inulosucrase
|
–
|
|
BRENDA:
BS375307;
BS375308
KEGG:
R04194;
R06059
MetaCyc:
RXN-15518
|
|
|
|
carbazole + O2 + NADH + H+ <=> 2''-aminobiphenyl-2,3-diol + NAD+
|
1.14.12.22
carbazole 1,9a-dioxygenase
|
–
|
|
BRENDA:
BR49375-a
KEGG:
R05414
MetaCyc:
RXN-11511_WOP
|
|
|
|
estriol + NADP+ <=> 16alpha-hydroxyestrone + NADPH + H+
|
1.1.1.62
17beta-estradiol 17-dehydrogenase
|
–
|
|
KEGG:
R04682
|
|
|
|
H2O + alpha-D-Glc-(1->2)-alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> beta-D-glucose + alpha-D-Glc-(1->3)-alpha-D-Glc-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
3.2.1.106
mannosyl-oligosaccharide glucosidase
|
–
|
|
KEGG:
R05979
|
|
|
|
1-phosphatidyl-1D-myo-inositol_3,4-bisphosphate + H2O <=> 1-phosphatidyl-1D-myo-inositol_5-phosphate + phosphate
|
3.1.3.66
phosphatidylinositol-3,4-bisphosphate 4-phosphatase
|
–
|
|
BRENDA:
BR48166;
BS415525
KEGG:
R07299
MetaCyc:
3.1.3.66-RXN
|
|
|
|
L-arabinose + NADH <=> L-arabitol + NAD+
|
1.1.1.14
L-iditol 2-dehydrogenase
1.1.1.21
aldose reductase
1.1.1.255
mannitol dehydrogenase
1.1.1.307
D-xylose reductase
|
–
–
–
–
|
|
BRENDA:
BS187754-a
KEGG:
R01758
SABIO-RK:
1857
|
|
|
|
Gibberellin_A24 <=> gibberellin_a9 + CO2
|
1.14.11.12
gibberellin-44 dioxygenase
|
–
|
|
KEGG:
R06326
SABIO-RK:
5908
|
|
|
|
spheroiden-2-one + H2O <=> Hydroxyspheroidenone
|
4.2.1.131
carotenoid 1,2-hydratase
|
–
|
|
KEGG:
R07539
|
|
|
|
prostaglandin_I2 + H2O <=> 6-keto-prostaglandin_F1alpha
|
not assigned
|
–
|
|
KEGG:
R03521
|
|
|
|
H+ + H2O + (S)-ureidoglycolate <=> NH3 + CO2 + glyoxylate
|
3.5.1.116
ureidoglycolate amidohydrolase
|
–
|
|
BRENDA:
BR29521;
BS190021
KEGG:
R00469
MetaCyc:
UREIDOGLYCOLATE-HYDROLASE-RXN
SABIO-RK:
230
|
|
|
|
Diacylglyceryl-2-aminoethylphosphonate <=> Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate
|
not assigned
|
–
|
|
KEGG:
R04923
|
|
|
|
chitin + H2O <=> chitosan + acetate
|
3.5.1.104
peptidoglycan-N-acetylglucosamine deacetylase
3.5.1.41
chitin deacetylase
|
–
–
|
|
BRENDA:
BR16071
KEGG:
R02333;
R06241
MetaCyc:
CHITIN-DEACETYLASE-RXN
SABIO-RK:
2283
|
|
|
|
dTDP-L-rhamnose + NADP+ <=> dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+
|
1.1.1.133
dTDP-4-dehydrorhamnose reductase
|
–
|
|
BRENDA:
BR29200
KEGG:
R02777
MetaCyc:
DTDPDEHYRHAMREDUCT-RXN
|
|
|
|
UDP-galactose + lactosylceramide <=> UDP + iGb3-Cer
|
2.4.1.87
N-acetyllactosaminide 3-alpha-galactosyltransferase
|
–
|
|
KEGG:
R11320
|
|
|
|
5-dehydroepisterol + NADPH + H+ + O2 <=> ergosta-5,7,22,24(28)-tetraen-3beta-ol + NADP+ + 2 H2O
|
1.14.19.41
sterol 22-desaturase
|
–
|
|
BRENDA:
BR51505;
BS432793
KEGG:
R07506
|
|
|
|
1H-indole-5,6-dione + O2 <=> Eumelanin + H2O
|
not assigned
|
–
|
|
KEGG:
R04886
|
|
|
|
(3R)-hydroxybutyryl-CoA <=> crotonyl-CoA + H2O
|
4.2.1.119
enoyl-CoA hydratase 2
4.2.1.150
short-chain-enoyl-CoA hydratase
4.2.1.17
enoyl-CoA hydratase
4.2.1.55
3-hydroxybutyryl-CoA dehydratase
4.2.1.59
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
|
–
–
–
–
–
|
|
BRENDA:
BR433;
BS18665
KEGG:
R03027;
R05595
MetaCyc:
3-HYDROXBUTYRYL-COA-DEHYDRATASE-RXN
SABIO-RK:
2877;
5195
|
|
|
|
(S)-3-methyl-2-oxopentanoate + Enzyme_N6-(lipoyl)lysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
KEGG:
R04225
|
|
|
|
1,3,4,6-tetrachloro-1,4-cyclohexadiene + H2O <=> 2,4,5-trichloro-2,5-cyclohexadiene-1-ol + Cl-
|
3.8.1.5
haloalkane dehalogenase
|
–
|
|
BRENDA:
BS394607
KEGG:
R05369
|
|
|
|
4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + ferricytochrome_b5 + H+ <=> 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8,24-dien-3beta-ol + ferricytochrome_b5 + H2O
|
1.14.18.9
4alpha-methylsterol monooxygenase
|
–
|
|
KEGG:
R07509
MetaCyc:
RXN-13712
|
|
|
|
S-adenosyl-L-methionine + (-)-pluviatolide <=> S-adenosyl-L-homocysteine + (-)-bursehernin + H+
|
2.1.1.323
(-)-pluviatolide 4-O-methyltransferase
|
–
|
|
BRENDA:
BR51592
KEGG:
R11230
MetaCyc:
RXN-16361
|
|
|
|
GDP-mannose + 1,4-beta-D-Mannan <=> GDP + 1,4-beta-D-Mannan
|
2.4.1
|
–
|
|
KEGG:
R00890
|
|
|
|
L-tryptophan + H2O <=> indole + pyruvate + NH3
|
4.1.99.1
tryptophanase
|
–
|
|
BRENDA:
BR6438
KEGG:
R00673
MetaCyc:
TRYPTOPHAN-RXN
SABIO-RK:
1053
|
|
|
|
phosphatidylglycerol + diglucosyldiacylglycerol <=> diacylglycerol + Glycerophosphoglycoglycerolipid
|
2.7.8.20
phosphatidylglycerol---membrane-oligosaccharide glycerophosphotransferase
|
–
|
|
KEGG:
R05081
|
|
|
|
GDP-mannose + alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol <=> GDP + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-1-PP-Dol
|
2.4.1.257
GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase
|
–
|
|
KEGG:
R06238
|
|
|
|
L-allo-threonine + NADP+ <=> L-2-amino-3-oxobutanoate + NADPH + H+
|
1.1.1.276
serine 3-dehydrogenase (NADP+)
1.1.1.381
3-hydroxy acid dehydrogenase
|
–
–
|
|
BRENDA:
BR51166
KEGG:
R10851
MetaCyc:
RXN-16000
|
|
|
|
5-Carboxymethyl-2-hydroxymuconate <=> (3E,5R)-5-carboxy-2-oxohept-3-enedioate
|
5.3.3.10
5-carboxymethyl-2-hydroxymuconate Delta-isomerase
|
–
|
|
BRENDA:
BR244;
BS1083
KEGG:
R04379
MetaCyc:
5.3.3.10-RXN
|
|
|
|
geranylgeranyl_diphosphate + indole-3-glycerol_phosphate <=> 3-Geranylgeranylindole + D-glyceraldehyde_3-phosphate + diphosphate
|
not assigned
|
–
|
|
KEGG:
R10349
MetaCyc:
RXN-15494
|
|
|
|
3,4-dihydroxyphenylacetaldehyde + NADP+ + H2O <=> 3,4-Dihydroxyphenylacetate + NADPH + H+
|
1.2.1.5
aldehyde dehydrogenase [NAD(P)+]
|
–
|
|
KEGG:
R03302
|
|
|
|
anthracene + NADH + H+ + O2 <=> cis-Anthracene_dihydrodiol + NAD+
|
1.14.12.12
naphthalene 1,2-dioxygenase
1.14.12.22
carbazole 1,9a-dioxygenase
|
–
–
|
|
BRENDA:
BS411631-a
KEGG:
R07704
|
|
|
|
ferulic_acid + ATP + CoA <=> feruloyl-CoA + AMP + diphosphate
|
6.2.1.12
4-coumarate---CoA ligase
6.2.1.34
trans-feruloyl-CoA synthase
|
–
–
|
|
BRENDA:
BS27
KEGG:
R02194
MetaCyc:
6.2.1.34-RXN
SABIO-RK:
2167
|
|
|
|
10-formyltetrahydrofolate + 5-aminoimidazole-4-carboxamide_ribonucleotide <=> tetrahydrofolate + 5-Formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide
|
2.1.2.3
phosphoribosylaminoimidazolecarboxamide formyltransferase
|
–
|
|
BRENDA:
BR43942
KEGG:
R04560
MetaCyc:
AICARTRANSFORM-RXN
SABIO-RK:
122
|
|
|
|
geranylgeranyl_diphosphate + H2O <=> cyclooctat-9-en-7-ol + diphosphate
|
4.2.3.146
cyclooctat-9-en-7-ol synthase
|
–
|
|
BRENDA:
BR51060
KEGG:
R10763
MetaCyc:
RXN-15429
|
|
|
|
2,3,5-Trichloro-cis,cis-muconate <=> 2,5-Dichloro-carboxymethylenebut-2-en-4-olide + Hydrochloric_acid
|
5.5.1.7
chloromuconate cycloisomerase
|
–
|
|
KEGG:
R06834
|
|
|
|
shikimate + pyrroloquinoline_quinone <=> 3-dehydroshikimate + reduced_pyrroloquinoline_quinone
|
1.1.5.8
quinate dehydrogenase (quinone)
|
–
|
|
KEGG:
R02415
|
|
|
|
L-erythro-3,5-diaminohexanoate + NAD+ + H2O <=> H+ + (S)-5-amino-3-oxohexanoate + NH3 + NADH
|
1.4.1.11
L-erythro-3,5-diaminohexanoate dehydrogenase
|
–
|
|
BRENDA:
BR36859
KEGG:
R03349
MetaCyc:
1.4.1.11-RXN
|
|
|
|
antheraxanthin + reduced_ferredoxin_[iron-sulfur]_cluster + H+ + O2 <=> violaxanthin + oxidized_ferredoxin + H2O
|
1.14.15.21
zeaxanthin epoxidase
|
–
|
|
BRENDA:
BR48605
KEGG:
R06947
MetaCyc:
RXN-7979
|
|
|
|
5beta-cholestane-3alpha,7alpha,26-triol <=> 3alpha,7alpha-Dihydroxy-5beta-cholestan-26-al
|
1.14.15.15
cholestanetriol 26-monooxygenase
|
–
|
|
KEGG:
R08758
|
|
|
|
N-acetylmuramic_acid + ATP <=> N-acetylmuramic_acid_1-phosphate + ADP + H+
|
2.7.1.221
N-acetylmuramate 1-kinase
|
–
|
|
BRENDA:
BR52172
KEGG:
R11024
MetaCyc:
RXN-18660
|
|
|
|
5-methyltetrahydrofolate + oxidized_ferredoxin <=> 5,10-methylenetetrahydrofolate + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.5.1.20
methylenetetrahydrofolate reductase [NAD(P)H]
1.5.7.1
methylenetetrahydrofolate reductase (ferredoxin)
|
–
–
|
|
BRENDA:
BR48613
KEGG:
R01217
MetaCyc:
RXN-5061
|
|
|
|
ATP + L-aspartate + NH3 <=> diphosphate + AMP + L-asparagine + H+
|
6.3.1.1
aspartate---ammonia ligase
6.3.5.4
asparagine synthase (glutamine-hydrolysing)
|
–
–
|
|
BRENDA:
BR93
KEGG:
R00483
MetaCyc:
ASNSYNA-RXN
|
|
|
|
7beta-(5-D-Aminoadipamido)-3-carbamoyloxymethylceph-3-em-4-carboxylic_acid + 2-oxoglutarate + O2 <=> 7a-Hydroxy-O-carbamoyl-deacetylcephalosporin_C + succinate + CO2
|
not assigned
|
–
|
|
KEGG:
R05302
|
|
|
|
phytyl_diphosphate + homogentisate + H+ <=> 2-methyl-6-phytylbenzene-1,4-diol + CO2 + diphosphate
|
2.5.1.115
homogentisate phytyltransferase
|
–
|
|
BRENDA:
BR50958
KEGG:
R07500
MetaCyc:
RXN-2541
|
|
|
|
GDP-mannose + Triacylated_phosphatidyl-myo-inositol_dimannoside <=> GDP + Triacylated_phosphatidyl-myo-inositol_trimannoside
|
2.4.1
|
–
|
|
KEGG:
R11994
|
|
|
|
5beta-pregnane-3,20-dione + acceptor <=> progesterone + reduced_acceptor
|
1.3.99.6
3-oxo-5beta-steroid 4-dehydrogenase
|
–
|
|
KEGG:
R02215
|
|
|
|
4-Guanidinobutanamide + H2O <=> NH3 + 4-Guanidinobutyrate
|
3.5.1.4
amidase
|
–
|
|
KEGG:
R03180
MetaCyc:
GUANIDINOBUTANAMIDE-NH3-RXN
|
|
|
|
5beta-cholestane-3alpha,7alpha,12alpha-triol + reduced_adrenodoxin + H+ + O2 <=> (25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol + oxidized_ferredoxin + H2O
|
1.14.15.15
cholestanetriol 26-monooxygenase
|
–
|
|
BRENDA:
BR50217;
BS288576
KEGG:
R04807
MetaCyc:
CHOLESTANETRIOL-26-MONOOXYGENASE-RXN
|
|
|
|
5-guanidino-2-oxopentanoate + H2O <=> 5-amino-2-oxopentanoate + Urea
|
3.5.3.7
guanidinobutyrase
|
–
|
|
KEGG:
R03250
MetaCyc:
RXN-7565
|
|
|
|
sulfite + 2 ferricytochrome_c + H2O <=> sulfate + 2 ferricytochrome_c + 2 H+
|
1.8.2.1
sulfite dehydrogenase (cytochrome)
1.8.3.1
sulfite oxidase
|
–
–
|
|
BRENDA:
BR36974
KEGG:
R00528
SABIO-RK:
946
|
|
|
|
4-chlorobiphenyl + O2 + NADPH + H+ <=> cis-2,3-Dihydro-2,3-dihydroxy-4''-chlorobiphenyl + NADP+
|
1.14.12.18
biphenyl 2,3-dioxygenase
|
–
|
|
KEGG:
R05262
|
|
|
|
CMP-beta-Kdo + alpha-Kdo-(2rarr6)-lipid_IVA_(E._coli) <=> alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid_IVA + CMP + H+
|
2.4.99.13
(Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase
|
–
|
|
BRENDA:
BR49180;
BS422764
KEGG:
R05074;
R06285
MetaCyc:
KDOTRANS2-RXN
|
|
|
|
nitrate + reduced_acceptor <=> nitrite + acceptor
|
1.5.1.20
methylenetetrahydrofolate reductase [NAD(P)H]
1.7.7.2
ferredoxin---nitrate reductase
1.7.99
1.9.6.1
nitrate reductase (cytochrome)
|
–
–
–
–
|
|
BRENDA:
BS260661
KEGG:
R00798
|
|
|
|
cinnamaldehyde + CoA + NADP+ <=> cinnamoyl-CoA + NADPH + H+
|
1.2.1.44
cinnamoyl-CoA reductase
|
–
|
|
BRENDA:
BR29404
KEGG:
R02506
MetaCyc:
CINNAMOYL-COA-REDUCTASE-RXN
|
|
|
|
GDP-L-fucose + paragloboside <=> GDP + 1,4-beta-D-galactosyl-(alpha-1,3-L-fucosyl)-N-acetyl-D-glucosaminyl-R
|
2.4.1
2.4.1.152
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase
2.4.1.65
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase
|
–
–
–
|
|
KEGG:
R06025
|
|
|
|
S-adenosyl-L-methionine + D-Cathine <=> (1S,2S)-2-(methylamino)-1-phenylpropan-1-ol + S-adenosyl-L-homocysteine + H+
|
2.1.1
2.1.1.M76
|
–
–
|
|
KEGG:
R08465
MetaCyc:
RXN-9342
|
|
|
|
H+ + melilotate + O2 + NADH <=> 3-(2,3-dihydroxyphenyl)propanoate + H2O + NAD+
|
1.14.13.4
melilotate 3-monooxygenase
|
–
|
|
BRENDA:
BR37130
KEGG:
R03369
MetaCyc:
MELILOTATE-3-MONOOXYGENASE-RXN
|
|
|
|
diacylglycerol + CDP-ethanolamine <=> phosphatidylethanolamine + CMP + H+
|
2.7.8.1
ethanolaminephosphotransferase
2.7.8.2
diacylglycerol cholinephosphotransferase
|
–
–
|
|
BRENDA:
BR47990
KEGG:
R02057
MetaCyc:
ETHANOLAMINEPHOSPHOTRANSFERASE-RXN
SABIO-RK:
2074
|
|
|
|
pyruvate + CoA + flavin + H+ <=> acetyl-CoA + CO2 + reduced_flavodoxin
|
1.2.7
1.2.7.1
pyruvate synthase
|
–
–
|
|
KEGG:
R10866
MetaCyc:
PYFLAVOXRE-RXN
|
|
|
|
H2O + pyruvate + ATP <=> H+ + phosphate + phosphoenolpyruvate + AMP
|
2.7.1.40
pyruvate kinase
2.7.9.2
pyruvate, water dikinase
|
–
–
|
|
BRENDA:
BR48097
KEGG:
R00199
MetaCyc:
PEPSYNTH-RXN
SABIO-RK:
148
|
|
|
|
2-Hydroxy-beta-keto-L-tyrosyl-[pcp] <=> 3-amino-4,7-dihydroxycoumarin
|
not assigned
|
–
|
|
KEGG:
R06765
|
|
|
|
gamma-tocopherol <=> 2,3-dimethyl-6-phytylbenzene-1,4-diol
|
5.5.1.24
tocopherol cyclase
|
–
|
|
BRENDA:
BR50792
KEGG:
R07502
MetaCyc:
RXN-2543
|
|
|
|
O2 + L-gulono-1,4-lactone <=> L-xylo-hex-3-ulonolactone + H2O2
|
1.1.3.8
L-gulonolactone oxidase
|
–
|
|
BRENDA:
BR47365
KEGG:
R03184
MetaCyc:
L-GULONOLACTONE-OXIDASE-RXN
|
|
|
|
L-rhamnulose_1-phosphate <=> L-lactaldehyde + dihydroxyacetone_phosphate
|
4.1.2.17
L-fuculose-phosphate aldolase
4.1.2.19
rhamnulose-1-phosphate aldolase
|
–
–
|
|
BRENDA:
BR350
KEGG:
R02263
MetaCyc:
RHAMNULPALDOL-RXN
SABIO-RK:
2230
|
|
|
|
cis-Zeatin_riboside_monophosphate + H2O <=> cis-Zeatin_riboside + phosphate
|
not assigned
|
–
|
|
KEGG:
R08079
MetaCyc:
RXN-4542
|
|
|
|
3-hydroxyisovaleryl-CoA <=> 3-methylcrotonoyl-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
|
–
|
|
KEGG:
R04137
SABIO-RK:
3858
|
|
|
|
feruloyl-CoA + agmatine <=> CoA + feruloyl_agmatine
|
2.3.1.64
agmatine N4-coumaroyltransferase
|
–
|
|
BRENDA:
BS321161;
BS454394
KEGG:
R09255
|
|
|
|
D-arabinose_5-phosphate <=> D-ribulose_5-phosphate
|
5.3.1.13
arabinose-5-phosphate isomerase
|
–
|
|
BRENDA:
BR222
KEGG:
R01530
MetaCyc:
DARAB5PISOM-RXN
SABIO-RK:
1696
|
|
|
|
UDP-galactose + glycoprotein_N-acetyl-D-galactosamine <=> beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl-R + UDP + H+
|
2.4.1.122
N-acetylgalactosaminide beta-1,3-galactosyltransferase
|
–
|
|
BRENDA:
BR47531;
BS355181
KEGG:
R05908
MetaCyc:
2.4.1.122-RXN
|
|
|
|
LL-2,6-Diaminoheptanedioate <=> meso-2,6-diaminoheptanedioate
|
5.1.1.10
amino-acid racemase
5.1.1.7
diaminopimelate epimerase
|
–
–
|
|
BRENDA:
BR175
KEGG:
R02735
MetaCyc:
DIAMINOPIMEPIM-RXN
|
|
|
|
7,9,12-Decaketide_intermediate_4 + NADPH + H+ <=> 7,9,12-Decaketide_intermediate_5 + NADP+
|
1.1.1
|
–
|
|
KEGG:
R09264
|
|
|
|
ATP + L-alanine + anticapsin <=> ADP + phosphate + L-alanyl-L-anticapsin + H+
|
6.3.2.49
L-alanine---L-anticapsin ligase
|
–
|
|
BRENDA:
BR48759
KEGG:
R11064
MetaCyc:
RXN-16296
|
|
|
|
squalene + 2 ferricytochrome_b5 + O2 + 2 H+ <=> (3S)-2,3-epoxy-2,3-dihydrosqualene + 2 ferricytochrome_b5 + H2O
|
1.14.19
|
–
|
|
KEGG:
R12355
|
|
|
|
N-acetyl-D-glucosaminyl-diphosphodolichol + UDP-N-acetyl-D-glucosamine <=> diphosphodolichyl-N-acetyl-D-glucosaminyl-N-acetyl-D-glucosamine + H+ + UDP
|
2.4.1.141
N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase
|
–
|
|
BRENDA:
BR47648
KEGG:
R04494;
R05970
MetaCyc:
2.4.1.141-RXN
|
|
|
|
diacylglycerol + CDP-choline <=> phosphatidylcholine + CMP + H+
|
2.7.8.1
ethanolaminephosphotransferase
2.7.8.2
diacylglycerol cholinephosphotransferase
|
–
–
|
|
BRENDA:
BR47989
KEGG:
R01321
MetaCyc:
RXN-5781
SABIO-RK:
1535
|
|
|
|
D-Cathinone <=> (-)-Norephedrine
|
not assigned
|
–
|
|
KEGG:
R08466
|
|
|
|
15,9''-di-cis-phytofluene + plastoquinone <=> 9,15,9''-tri-cis-zeta-carotene + plastoquinol
|
1.3.5.5
15-cis-phytoene desaturase
|
–
|
|
BRENDA:
BR49668
KEGG:
R09654
MetaCyc:
RXN-12244
|
|
|
|
inositol_3,4,5,6-tetrakisphosphate + ATP <=> H+ + 1D-myo-inositol_1,3,4,5,6-pentakisphosphate + ADP
|
2.7.1.134
inositol-tetrakisphosphate 1-kinase
2.7.1.151
inositol-polyphosphate multikinase
2.7.1.159
inositol-1,3,4-trisphosphate 5/6-kinase
2.7.4.21
inositol-hexakisphosphate kinase
|
–
–
–
–
|
|
BRENDA:
BR47746;
BR48647
KEGG:
R03479;
R05801
MetaCyc:
2.7.1.134-RXN;
RXN-7162
SABIO-RK:
3273;
5392
|
|
|
|
(22S)-22-hydroxycampesterol <=> (22S)-22-hydroxycampest-4-en-3-one
|
not assigned
|
–
|
|
KEGG:
R07446
|
|
|
|
trypanothione + dehydroascorbate <=> trypanothione_disulfide + ascorbate
|
not assigned
|
–
|
|
KEGG:
R08358
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose
|
5.3.2.3
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming)
|
–
|
|
BRENDA:
BR49956
KEGG:
R09904
MetaCyc:
RXN-12839
|
|
|
|
D-lactate + 2 ferricytochrome_c <=> pyruvate + 2 ferricytochrome_c + 2 H+
|
1.1.2.4
D-lactate dehydrogenase (cytochrome)
|
–
|
|
BRENDA:
BR36726
KEGG:
R00197
|
|
|
|
coenzyme_B + coenzyme_M + reduced_ferredoxin_[iron-sulfur]_cluster + CO2 <=> CoM-S-S-CoB + formate + oxidized_ferredoxin
|
1.8.98.6
formate:CoB-CoM heterodisulfide,ferredoxin reductase
|
–
|
|
BRENDA:
BR52242
KEGG:
R11944
MetaCyc:
RXN-18529
|
|
|
|
dichloroarcyriaflavin_A + D-glucose <=> 4''-O-demethylrebeccamycin + H2O
|
4.3.3.5
4'-demethylrebeccamycin synthase
|
–
|
|
BRENDA:
BR49244
KEGG:
R09568
MetaCyc:
RXN-10846
|
|
|
|
amygdalin + H2O <=> prunasin + D-glucose
|
3.2.1.117
amygdalin beta-glucosidase
3.2.1.21
beta-glucosidase
|
–
–
|
|
BRENDA:
BR48182
KEGG:
R02985
MetaCyc:
AMYGDALIN-BETA-GLUCOSIDASE-RXN
SABIO-RK:
2837
|
|
|
|
9,14-Decaketide_intermediate_1 <=> tetracenomycin_F2 + [acyl-carrier_protein]
|
not assigned
|
–
|
|
KEGG:
R09355
|
|
|
|
dolichol + CTP <=> dolichyl_phosphate + H+ + CDP
|
2.7.1.108
dolichol kinase
|
–
|
|
BRENDA:
BR47722
KEGG:
R01018
MetaCyc:
DOLICHOL-KINASE-RXN
|
|
|
|
D-Lactaldehyde + NAD+ <=> methylglyoxal + NADH + H+
|
1.1.1.78
methylglyoxal reductase (NADH)
1.1.1.79
glyoxylate reductase (NADP+)
|
–
–
|
|
BRENDA:
BR22616
KEGG:
R02527
MetaCyc:
D-LACTALDEHYDE-DEHYDROGENASE-RXN
|
|
|
|
a_very-long-chain_(3R)-3-hydroxyacyl-CoA <=> very-long-chain_(2E)-2-enoyl-CoA + H2O
|
4.2.1.134
very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
|
–
|
|
BRENDA:
BR50205
KEGG:
R10827
MetaCyc:
RXN-11750
|
|
|
|
thiamine + ATP <=> H+ + thiamine_phosphate + ADP
|
2.7.1.89
thiamine kinase
|
–
|
|
BRENDA:
BR47814
KEGG:
R02134
MetaCyc:
THIKIN-RXN
|
|
|
|
L-phenylalanine + O2 <=> phenylacetamide + CO2 + H2O
|
1.11.1.21
catalase-peroxidase
1.13.12.3
tryptophan 2-monooxygenase
1.13.12.9
phenylalanine 2-monooxygenase
|
–
–
–
|
|
BRENDA:
BR40461
KEGG:
R00690;
R00698
MetaCyc:
PHENYLALANINE-2-MONOOXYGENASE-RXN
SABIO-RK:
1070
|
|
|
|
H+ + L-ornithine <=> CO2 + putrescine
|
4.1.1.17
ornithine decarboxylase
4.1.1.18
lysine decarboxylase
4.1.1.19
arginine decarboxylase
4.1.1.86
diaminobutyrate decarboxylase
4.1.1.B12
|
–
–
–
–
–
|
|
BRENDA:
BR277
KEGG:
R00670
MetaCyc:
ORNDECARBOX-RXN
SABIO-RK:
1050
|
|
|
|
benzoyl-CoA + glycine <=> H+ + hippuric_acid + CoA
|
2.3.1.13
glycine N-acyltransferase
2.3.1.14
glutamine N-phenylacetyltransferase
2.3.1.71
glycine N-benzoyltransferase
|
–
–
–
|
|
BRENDA:
BR44073
KEGG:
R02452
MetaCyc:
GLYCINE-N-BENZOYLTRANSFERASE-RXN
SABIO-RK:
2385
|
|
|
|
(R)-3-hydroxydodecanoyl-[acyl-carrier_protein] + NADP+ <=> 3-oxododecanoyl-[acyl-carrier_protein] + NADPH + H+
|
1.1.1
1.1.1.100
3-oxoacyl-[acyl-carrier-protein] reductase
2.3.1
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
–
–
–
|
|
KEGG:
R04964
|
|
|
|
mono(2-hydroxyethyl)_terephthalate + H2O <=> terephthalate + ethylene_glycol + H+
|
3.1.1.102
mono(ethylene terephthalate) hydrolase
|
–
|
|
BRENDA:
BR51770
KEGG:
R11541
MetaCyc:
RXN-17826
|
|
|
|
alpha-D-glucose_6-phosphate <=> beta-D-glucose_6-phosphate
|
5.1.3.15
glucose-6-phosphate 1-epimerase
5.1.3.3
aldose 1-epimerase
5.3.1.9
glucose-6-phosphate isomerase
|
–
–
–
|
|
BRENDA:
BR190
KEGG:
R02739
MetaCyc:
GLUCOSE-6-PHOSPHATE-1-EPIMERASE-RXN
SABIO-RK:
13
|
|
|
|
gamma-carotene <=> beta-carotene
|
5.5.1.19
lycopene beta-cyclase
|
–
|
|
BRENDA:
BS427448
KEGG:
R03824
MetaCyc:
RXN1F-151
|
|
|
|
dTDP-4-hydroxyamino-4,6-dideoxy-alpha-D-glucose + Calicheamicinone <=> dTDP + Calicheamicin_T0
|
2.4.1
|
–
|
|
KEGG:
R11417
|
|
|
|
linoleic_acid + O2 + NADPH + H+ <=> (12Z,9R,10S)-9,10-epoxyoctadec-12-enoate + NADP+ + H2O
|
1.14.13
1.14.14
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
|
KEGG:
R07055
|
|
|
|
L-serine + acetyl-CoA <=> O-acetyl-L-serine + CoA
|
2.3.1.30
serine O-acetyltransferase
|
–
|
|
BRENDA:
BR44030
KEGG:
R00586
MetaCyc:
SERINE-O-ACETTRAN-RXN
SABIO-RK:
986
|
|
|
|
S-adenosyl-L-methionine + Orsellinate-[acp] <=> S-adenosyl-L-homocysteine + 2-Methoxyorsellinate-[acp]
|
2.1.1
|
–
|
|
KEGG:
R11413
|
|
|
|
FMN + H2O <=> riboflavin + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.102
FMN hydrolase
3.1.3.104
5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase
3.1.3.2
acid phosphatase
3.1.3.8
3-phytase
|
–
–
–
–
–
|
|
BRENDA:
BR51716
KEGG:
R00548
MetaCyc:
RXN0-5187
SABIO-RK:
964
|
|
|
|
pyridoxine_5''-phosphate + H2O <=> pyridoxine + phosphate
|
3.1.3.2
acid phosphatase
3.1.3.74
pyridoxal phosphatase
|
–
–
|
|
BRENDA:
BS374485
KEGG:
R01911
MetaCyc:
RXN-14181
SABIO-RK:
1965
|
|
|
|
benzoate + NADPH + H+ + O2 <=> (1R,6S)-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate + NADP+
|
1.14.12.10
benzoate 1,2-dioxygenase
|
–
|
|
KEGG:
R05622
|
|
|
|
2,3-dehydroadipyl-CoA + acetyl-CoA <=> 3-oxo-5,6-dehydrosuberyl-CoA + CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.223
3-oxo-5,6-didehydrosuberyl-CoA thiolase
|
–
–
|
|
BRENDA:
BR50536
KEGG:
R09839
MetaCyc:
RXN0-6512
|
|
|
|
protein_Npi-phospho-L-histidine + D-fructose <=> protein_L-histidine + D-Fructose_1-phosphate
|
2.7.1.202
protein-Npi-phosphohistidine---D-fructose phosphotransferase
|
–
|
|
KEGG:
R03232
SABIO-RK:
9121
|
|
|
|
(S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate + O2 <=> 4-hydroxyphenylglyoxylate + H2O2
|
1.1.3.46
4-hydroxymandelate oxidase
|
–
|
|
BRENDA:
BR50849
KEGG:
R06633
MetaCyc:
RXN-15300
|
|
|
|
p-coumaryl_alcohol + NADP+ <=> 4-coumaraldehyde + NADPH + H+
|
1.1.1.195
cinnamyl-alcohol dehydrogenase
|
–
|
|
BRENDA:
BS230433;
BS426143
KEGG:
R07437
MetaCyc:
RXN-1102
SABIO-RK:
3739
|
|
|
|
Tropine + (R)-phenyllactyl-CoA <=> Littorine + CoA
|
2.3.1
2.3.1.185
tropine acyltransferase
|
–
–
|
|
KEGG:
R08432
MetaCyc:
RXN-8254
|
|
|
|
(1''S)-averantin + NADP+ <=> norsolorinic_acid + NADPH + H+
|
1.1.1.349
norsolorinic acid ketoreductase
1.1.1.B25
|
–
–
|
|
BRENDA:
BR50499
KEGG:
R10309
MetaCyc:
RXN-9480
|
|
|
|
TDP-3-dimethylamino-4,6-dideoxy-alpha-D-glucopyranose + L-oleandrosyl-oleandolide <=> oleandomycin + dTDP + H+
|
2.4.1
|
–
|
|
KEGG:
R06457
MetaCyc:
RXN-12803
|
|
|
|
UDP-glucose + beta-D-glucosyl_crocetin <=> H+ + beta-D-gentiobiosyl_crocetin + UDP
|
2.4.1.330
beta-D-glucosyl crocetin beta-1,6-glucosyltransferase
|
–
|
|
BRENDA:
BR51083
KEGG:
R10988
MetaCyc:
RXN-8472
|
|
|
|
deoxyamidinoproclavaminate + 2-oxoglutarate + O2 <=> amidinoproclavaminate + succinate + CO2
|
1.14.11.21
clavaminate synthase
|
–
|
|
BRENDA:
BR47603
KEGG:
R05466
MetaCyc:
1.14.11.21-RXN
|
|
|
|
S-adenosyl-L-methionine + precorrin-3B <=> H+ + precorrin-4 + S-adenosyl-L-homocysteine
|
2.1.1.131
precorrin-3B C17-methyltransferase
|
–
|
|
BRENDA:
BR1454
KEGG:
R05180
MetaCyc:
2.1.1.131-RXN
|
|
|
|
O-phospho-L-serine + thiosulfate <=> S-sulfocysteine + phosphate
|
2.5.1.65
O-phosphoserine sulfhydrylase
2.8.5.1
S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent)
|
–
–
|
|
BRENDA:
BR52420
KEGG:
R12092
MetaCyc:
RXN-18665
|
|
|
|
(S)-cis-N-Methylstylopine + reduced_flavodoxin + O2 <=> protopine + flavin + H2O
|
1.14.14.97
methyltetrahydroprotoberberine 14-monooxygenase
|
–
|
|
BRENDA:
BS186710
KEGG:
R04700
|
|
|
|
S-adenosyl-L-methionine + phosphatidyl-N,N-dimethylethanolamine <=> phosphatidylcholine + S-adenosyl-L-homocysteine + H+
|
2.1.1.16
methylene-fatty-acyl-phospholipid synthase
2.1.1.17
phosphatidylethanolamine N-methyltransferase
2.1.1.71
phosphatidyl-N-methylethanolamine N-methyltransferase
|
–
–
–
|
|
BRENDA:
BS319863
KEGG:
R01320
MetaCyc:
RXN4FS-2
SABIO-RK:
1534
|
|
|
|
2 3,5-diiodo-L-tyrosine + H2O2 <=> L-thyroxine + 2-aminoacrylate + 2 H2O
|
1.11.1.8
iodide peroxidase
|
–
|
|
KEGG:
R03208
|
|
|
|
5-diphosphomevalonate + ATP <=> isopentenyl_diphosphate + CO2 + ADP + phosphate
|
4.1.1.33
diphosphomevalonate decarboxylase
|
–
|
|
BRENDA:
BR292
KEGG:
R01121
MetaCyc:
DIPHOSPHOMEVALONTE-DECARBOXYLASE-RXN
SABIO-RK:
1380
|
|
|
|
2-carboxymethyl-3-hydroxyphenylpropionyl-CoA + NAD+ <=> Benzoylsuccinyl-CoA + NADH + H+
|
1.1.1
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
KEGG:
R05575
MetaCyc:
RXN-905
|
|
|
|
Leucocyanidin + 2-oxoglutarate + O2 + H+ <=> cyanidin + succinate + CO2 + 2 H2O
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
BRENDA:
BS397692
KEGG:
R05036
|
|
|
|
catechol + O2 <=> H+ + cis,cis-muconate
|
1.13.11.1
catechol 1,2-dioxygenase
1.13.11.3
protocatechuate 3,4-dioxygenase
1.13.11.37
hydroxyquinol 1,2-dioxygenase
|
–
–
–
|
|
BRENDA:
BR37023
KEGG:
R00817
MetaCyc:
CATECHOL-12-DIOXYGENASE-RXN
SABIO-RK:
1160
|
|
|
|
2-Methylbenzyl_alcohol + NAD+ <=> 2-Methylbenzaldehyde + NADH
|
1.1.1.90
aryl-alcohol dehydrogenase
|
–
|
|
BRENDA:
BS257261
KEGG:
R05348
|
|
|
|
hercynine + L-cysteine + O2 <=> S-(hercyn-2-yl)-L-cysteine_S-oxide + H2O
|
1.14.99.51
hercynylcysteine S-oxide synthase
|
–
|
|
BRENDA:
BR51394
KEGG:
R11014
MetaCyc:
RXN-15801
|
|
|
|
2-aminomuconate + H2O <=> 2-hydroxy-2,4-hexadienedioate + NH3
|
3.5.99.11
2-aminomuconate deaminase (2-hydroxymuconate-forming)
3.5.99.5
2-aminomuconate deaminase
|
–
–
|
|
BRENDA:
BR51717;
BS116425
KEGG:
R03887;
R11532
MetaCyc:
RXN-8845
|
|
|
|
cannabigerolate + O2 <=> cannabidiolate + H2O2
|
1.21.3.3
reticuline oxidase
1.21.3.8
cannabidiolic acid synthase
|
–
–
|
|
BRENDA:
BR50270;
BS443261
KEGG:
R10160
MetaCyc:
RXN-7855
|
|
|
|
D-lactate + NAD+ <=> pyruvate + NADH + H+
|
1.1.1.27
L-lactate dehydrogenase
1.1.1.28
D-lactate dehydrogenase
1.1.1.345
D-2-hydroxyacid dehydrogenase (NAD+)
|
–
–
–
|
|
BRENDA:
BR29291
KEGG:
R00704
MetaCyc:
DLACTDEHYDROGNAD-RXN
SABIO-RK:
155
|
|
|
|
N2-Acetyl-L-ornithine + Carbamoyl_phosphate <=> H+ + N-acetyl-L-citrulline + phosphate
|
2.1.3.11
N-succinylornithine carbamoyltransferase
2.1.3.9
N-acetylornithine carbamoyltransferase
|
–
–
|
|
BRENDA:
BR48711
KEGG:
R07245
MetaCyc:
2.1.3.9-RXN
|
|
|
|
S-(Indolylmethylthiohydroximoyl)-L-cysteine + H2O <=> 2-(3-indolyl)acetothiohydroximate + pyruvate + NH3
|
4.4.1
|
–
|
|
KEGG:
R08170
|
|
|
|
leukotriene_C4 <=> leukotriene_A4 + glutathione
|
4.4.1.20
leukotriene-C4 synthase
|
–
|
|
BRENDA:
BR48007
KEGG:
R03059
MetaCyc:
LEUKOTRIENE-C4-SYNTHASE-RXN
SABIO-RK:
8569
|
|
|
|
peptidyl-4-carboxyglutamate + 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + H+ + H2O <=> CO2 + peptidyl-glutamate + vitamin_KH2 + O2
|
4.1.1.90
peptidyl-glutamate 4-carboxylase
|
–
|
|
BRENDA:
BR49124;
BS427500
KEGG:
R05144
MetaCyc:
RXN-10683
|
|
|
|
GTP + H2O <=> 7,8-dihydroneopterin_2,3''-cyclic_phosphate + formate + diphosphate + H+
|
3.5.4.16
GTP cyclohydrolase I
3.5.4.39
GTP cyclohydrolase IV
|
–
–
|
|
BRENDA:
BR50468
KEGG:
R10348
MetaCyc:
RXN-10063
|
|
|
|
L-aspartate + acetyl-CoA <=> N-acetyl-L-aspartate + CoA + H+
|
2.3.1.17
aspartate N-acetyltransferase
|
–
|
|
BRENDA:
BR44015
KEGG:
R00487
MetaCyc:
ASPARTATE-N-ACETYLTRANSFERASE-RXN
|
|
|
|
trypanothione + Tryparedoxin_disulfide <=> trypanothione_disulfide + tryparedoxin
|
not assigned
|
–
|
|
KEGG:
R08361
|
|
|
|
D-Lactaldehyde + NAD+ + H2O <=> H+ + D-lactate + NADH
|
1.2.1.22
lactaldehyde dehydrogenase
1.2.1.23
2-oxoaldehyde dehydrogenase (NAD+)
1.2.1.3
aldehyde dehydrogenase (NAD+)
|
–
–
–
|
|
BRENDA:
BS189164
KEGG:
R01735
MetaCyc:
LACTALDEHYDE-OXI-RXN
SABIO-RK:
548
|
|
|
|
7-hydroxychlorophyllide_a <=> chlorophyllide_a
|
not assigned
|
–
|
|
KEGG:
R09066
|
|
|
|
pyruvate + H2O + ubiquinone <=> CO2 + ubiquinol + acetate
|
1.2.5.1
pyruvate dehydrogenase (quinone)
|
–
|
|
BRENDA:
BR49235
KEGG:
R03145
MetaCyc:
RXN-11496
|
|
|
|
O-succinyl-L-homoserine + L-selenocysteine <=> L-selenocystathionine + succinate
|
2.5.1.48
cystathionine gamma-synthase
|
–
|
|
KEGG:
R04946
|
|
|
|
[Lipoyl-carrier_protein_E2]-N6-octanoyl-L-lysine + an_[Fe-S]_cluster_scaffold_protein_carrying_a_[4Fe-4S]2+_cluster + 2 S-adenosyl-L-methionine + 2 [2Fe-2S]-center + 8 H+ <=> enzyme_N6-(dihydrolipoyl)lysine + an_[Fe-S]_cluster_scaffold_protein + 2 Sulfide + 4 Fe2+ + 2 L-methionine + 2 5''-Deoxyadenosine + 2 [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
|
KEGG:
R12423
|
|
|
|
D-ribitol_5-phosphate + NADP+ <=> D-ribulose_5-phosphate + NADPH + H+
|
1.1.1.137
ribitol-5-phosphate 2-dehydrogenase
1.1.1.405
ribitol-5-phosphate 2-dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BR29203
KEGG:
R01525
MetaCyc:
RIBITOL-5-PHOSPHATE-2-DEHYDROGENASE-RXN;
RXN-18411
SABIO-RK:
1694
|
|
|
|
thiamine_diphosphate + H2O <=> H+ + thiamine_phosphate + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.100
thiamine phosphate phosphatase
3.1.3.2
acid phosphatase
3.6.1
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.28
thiamine-triphosphatase
3.6.1.5
apyrase
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.6
nucleoside diphosphate phosphatase
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS141322;
BS141393
KEGG:
R00615;
R02092
MetaCyc:
RXN-14213;
RXN0-3542
SABIO-RK:
495;
9603
|
|
|
|
H+ + Clavulanate-9-aldehyde + NADPH <=> clavulanic_acid + NADP+
|
not assigned
|
–
|
|
KEGG:
R05471
MetaCyc:
RXN-8893
|
|
|
|
2-carboxymethyl-3-hydroxyphenylpropionyl-CoA <=> (E)-2-benzylidenesuccinyl-CoA + H2O
|
4.2.1
|
–
|
|
KEGG:
R05599
MetaCyc:
RXN-902
|
|
|
|
lactoyl-CoA <=> acryloyl-CoA + H2O
|
4.2.1
4.2.1.54
lactoyl-CoA dehydratase
|
–
–
|
|
BRENDA:
BS18742
KEGG:
R02963
MetaCyc:
RXN-781
|
|
|
|
FMN + O2 <=> 8-demethyl-8-formylriboflavin_5''-phosphate + H2O
|
2.6.1.114
8-demethyl-8-aminoriboflavin-5'-phosphate synthase
|
–
|
|
BRENDA:
BR52324
KEGG:
R11961
MetaCyc:
RXN-18509
|
|
|
|
L-homoserine + succinyl-CoA <=> O-succinyl-L-homoserine + CoA
|
2.3.1.46
homoserine O-succinyltransferase
|
–
|
|
BRENDA:
BR44047
KEGG:
R01777
MetaCyc:
HOMSUCTRAN-RXN
|
|
|
|
(S)-3-hydroxy-2-methylpropanoyl-CoA <=> methacryloyl-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
|
–
|
|
KEGG:
R04224
MetaCyc:
METHYLACYLYLCOA-HYDROXY-RXN
SABIO-RK:
3935
|
|
|
|
4-Chlorophenol + O2 + NADPH + H+ <=> 4-Chlorocatechol + H2O + NADP+
|
1.14.13.20
2,4-dichlorophenol 6-monooxygenase
1.14.13.7
phenol 2-monooxygenase (NADPH)
|
–
–
|
|
BRENDA:
BS386143
KEGG:
R05441
MetaCyc:
RXN-10125
|
|
|
|
amylose <=> alpha-cyclodextrin
|
2.4.1.19
cyclomaltodextrin glucanotransferase
3.2.1.54
cyclomaltodextrinase
|
–
–
|
|
BRENDA:
BR16009;
BS372798;
BS377790;
BS389790;
BS408388
KEGG:
R03122;
R06160;
R11260
MetaCyc:
2.4.1.19-RXN;
CYCLOMALTODEXTRINASE-RXN;
RXN-12181
SABIO-RK:
13624
|
|
|
|
24-ethylidenelophenol + ferricytochrome_b5 + O2 + H+ <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + ferricytochrome_b5 + H2O
|
1.14.18.11
plant 4alpha-monomethylsterol monooxygenase
|
–
|
|
BRENDA:
BS446036
KEGG:
R12379
MetaCyc:
RXN-19723
|
|
|
|
cytidine + phosphate <=> cytosine + alpha-D-ribose_1-phosphate
|
2.4.2.2
pyrimidine-nucleoside phosphorylase
2.4.2.3
uridine phosphorylase
|
–
–
|
|
BRENDA:
BS355365
KEGG:
R02296
|
|
|
|
tetracenomycin_B2 + O2 + NADPH + H+ <=> 8-demethyltetracenomycin_C + H2O + NADP+
|
1.14.13.200
tetracenomycin A2 monooxygenase-dioxygenase
|
–
|
|
BRENDA:
BS429406
KEGG:
R10954
MetaCyc:
RXN-15407
|
|
|
|
S-adenosyl-L-methionine + L-histidine <=> hercynine + S-adenosyl-L-homocysteine + H+
|
2.1.1.44
L-histidine Nalpha-methyltransferase
|
–
|
|
BRENDA:
BR50754
KEGG:
R01169
MetaCyc:
RXN-14431
|
|
|
|
oxidized_ferredoxin + formylmethanofuran + H2O <=> reduced_ferredoxin_[iron-sulfur]_cluster + methanofuran + CO2 + H+
|
1.2.7.12
formylmethanofuran dehydrogenase
|
–
|
|
BRENDA:
BR1152;
BS413330;
BS438336
KEGG:
R03015;
R11743
MetaCyc:
FORMYLMETHANOFURAN-DEHYDROGENASE-RXN
|
|
|
|
3,4-dihydroxyphenyllactic_acid + NAD+ <=> 3,4-Dihydroxyphenylpyruvate + NADH + H+
|
1.1.1.237
hydroxyphenylpyruvate reductase
1.1.1.28
D-lactate dehydrogenase
|
–
–
|
|
BRENDA:
BR52505-a
KEGG:
R03373
MetaCyc:
RXN-7632_WOP
|
|
|
|
methylmalonate <=> L-2-methyl-3-oxopropionate
|
not assigned
|
–
|
|
KEGG:
R03872
|
|
|
|
2-phospho-D-glycerate <=> 3-phospho-D-glycerate
|
5.4.2.11
phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
5.4.2.12
phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
|
–
–
|
|
BRENDA:
BR17
KEGG:
R01518
MetaCyc:
3PGAREARR-RXN;
RXN-15513
SABIO-RK:
7641
|
|
|
|
O2 + H2O + pyridoxal <=> H+ + H2O2 + 4-pyridoxate
|
1.2.3.1
aldehyde oxidase
1.2.3.8
pyridoxal oxidase
|
–
–
|
|
BRENDA:
BS258253
KEGG:
R01709
MetaCyc:
PYRIDOXAL-OXIDASE-RXN
|
|
|
|
ATP + CoA + 4-Chlorobenzoate <=> diphosphate + AMP + 4-chlorobenzoyl-CoA
|
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.25
benzoate---CoA ligase
6.2.1.33
4-chlorobenzoate---CoA ligase
|
–
–
–
|
|
BRENDA:
BR86
KEGG:
R03932
MetaCyc:
6.2.1.33-RXN
SABIO-RK:
3673
|
|
|
|
2,4-Dichlorobenzoate + CoA + ATP <=> 2,4-dichlorobenzoyl-CoA + AMP + diphosphate
|
6.2.1
|
–
|
|
KEGG:
R05451
MetaCyc:
RXN-16776
|
|
|
|
UDP-galactose + beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-[beta-D-GlcNAc-(1->6)]-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc-1-Cer <=> UDP + nLc6Cer
|
2.4.1
|
–
|
|
KEGG:
R06021
|
|
|
|
lanosterol + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + oxidized_ferredoxin + H2O
|
1.14.15.36
sterol 14alpha-demethylase (ferredoxin)
|
–
|
|
KEGG:
R12323
MetaCyc:
RXN-20130
|
|
|
|
dTDP + ATP <=> dTTP + ADP
|
2.7.4.6
nucleoside-diphosphate kinase
|
–
|
|
BRENDA:
BS358250
KEGG:
R02093
MetaCyc:
DTDPKIN-RXN
SABIO-RK:
423
|
|
|
|
4-deoxy-L-threo-5-hexosulose-uronate <=> (4S)-4,6-dihydroxy-2,5-dioxohexanoate
|
5.3.1.17
5-dehydro-4-deoxy-D-glucuronate isomerase
|
–
|
|
BRENDA:
BR226
KEGG:
R04383
MetaCyc:
5.3.1.17-RXN
|
|
|
|
2-dehydro-3-deoxy-L-rhamnonate <=> pyruvate + L-lactaldehyde
|
4.1.2.53
2-keto-3-deoxy-L-rhamnonate aldolase
|
–
|
|
BRENDA:
BR50712
KEGG:
R02261
MetaCyc:
RXN0-5433
|
|
|
|
Leucocyanidin + NADP+ <=> taxifolin + NADPH + H+
|
1.1.1.219
dihydroflavonol 4-reductase
|
–
|
|
BRENDA:
BS230654;
BS371573
KEGG:
R03636
MetaCyc:
RXN-600
|
|
|
|
3-dehydroshikimate <=> 3,4-dihydroxybenzoate + H2O
|
4.2.1.118
3-dehydroshikimate dehydratase
|
–
|
|
BRENDA:
BR49127
KEGG:
R01627
MetaCyc:
DHSHIKIMATE-DEHYDRO-RXN
SABIO-RK:
1768
|
|
|
|
adenylyl-molybdopterin + molybdate + H+ <=> molybdenum_cofactor + AMP + H2O
|
2.10.1.1
molybdopterin molybdotransferase
|
–
|
|
BRENDA:
BR49440
KEGG:
R09735
MetaCyc:
RXN-8348
|
|
|
|
UDP-glucose + bis(beta-D-glucosyl)_crocetin <=> H+ + beta-D-gentiobiosyl_beta-D-glucosyl_crocetin + UDP
|
2.4.1.330
beta-D-glucosyl crocetin beta-1,6-glucosyltransferase
|
–
|
|
BRENDA:
BR51084
KEGG:
R10989
MetaCyc:
RXN-8474
|
|
|
|
ethanolamine_plasmalogen + H2O <=> 1-alkenylglycerophosphoethanolamine + a_carboxylate
|
3.1.1.4
phospholipase A2
|
–
|
|
KEGG:
R07379
|
|
|
|
H2O + 2-(5-oxo-4,5-dihydrofuran-2-yl)acetic_acid <=> H+ + 3-oxoadipate
|
3.1.1.24
3-oxoadipate enol-lactonase
|
–
|
|
BRENDA:
BR11711
KEGG:
R02991
MetaCyc:
3-OXOADIPATE-ENOL-LACTONASE-RXN
|
|
|
|
adenosylcobyrinic_acid_a,c-diamide + L-glutamine + ATP + H2O <=> H+ + L-glutamate + adenosylcobyric_acid + ADP + phosphate
|
6.3.5.10
adenosylcobyric acid synthase (glutamine-hydrolysing)
|
–
|
|
BRENDA:
BR48011
KEGG:
R05225
MetaCyc:
R345-RXN
|
|
|
|
1D-myo-inositol_1,4,5-trisphosphate + ATP <=> H+ + 1D-myo-inositol_1,4,5,6-tetrakisphosphate + ADP
|
2.7.1.151
inositol-polyphosphate multikinase
|
–
|
|
BRENDA:
BR36943
KEGG:
R05800
MetaCyc:
2.7.1.151-RXN
SABIO-RK:
5391
|
|
|
|
dihydroxyacetone_phosphate <=> methylglyoxal + phosphate
|
4.1.2.17
L-fuculose-phosphate aldolase
4.2.3.3
methylglyoxal synthase
5.3.1.1
triose-phosphate isomerase
|
–
–
–
|
|
BRENDA:
BR16092
KEGG:
R01016
MetaCyc:
METHGLYSYN-RXN
SABIO-RK:
176
|
|
|
|
D-glucose_6-phosphate <=> alpha-D-glucosamine_1-phosphate
|
5.4.2.10
phosphoglucosamine mutase
5.4.2.13
phosphogalactosamine mutase
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3
phosphoacetylglucosamine mutase
5.4.2.8
phosphomannomutase
|
–
–
–
–
–
|
|
BRENDA:
BR22836;
BS141667;
BS141668
KEGG:
R02060
MetaCyc:
5.4.2.10-RXN
SABIO-RK:
2077
|
|
|
|
dTDP-3-O-methyl-4-oxo-2,6-dideoxy-L-mannose <=> dTDP-L-oleandrose
|
not assigned
|
–
|
|
KEGG:
R11042
|
|
|
|
glycolate + O2 <=> glyoxylate + H2O2
|
1.1.3.13
alcohol oxidase
1.1.3.15
(S)-2-hydroxy-acid oxidase
|
–
–
|
|
BRENDA:
BS257485
KEGG:
R00475
MetaCyc:
RXN-969
SABIO-RK:
907
|
|
|
|
4-hydroxybutyrate + ATP + CoA <=> 4-hydroxybutanoyl-CoA + AMP + diphosphate
|
6.2.1.40
4-hydroxybutyrate---CoA ligase (AMP-forming)
|
–
|
|
BRENDA:
BR51010
KEGG:
R09279
MetaCyc:
RXN-9092
|
|
|
|
L-dihydroorotate + fumarate <=> Orotate + succinate
|
1.3.98.1
dihydroorotate dehydrogenase (fumarate)
|
–
|
|
BRENDA:
BR49571
KEGG:
R01867
MetaCyc:
RXN-9929
SABIO-RK:
7103
|
|
|
|
phenylpyruvate + O2 <=> 2-hydroxyphenylacetate + CO2
|
1.13.11.27
4-hydroxyphenylpyruvate dioxygenase
|
–
|
|
BRENDA:
BS260708
KEGG:
R01372
MetaCyc:
RXN-10815
SABIO-RK:
1574
|
|
|
|
(6E)-8-hydroxygeraniol + NADP+ <=> (6E)-8-oxogeranial + NADPH + H+
|
1.1.1.324
8-hydroxygeraniol dehydrogenase
|
–
|
|
BRENDA:
BR50014
KEGG:
R08499
MetaCyc:
RXN-12961
|
|
|
|
Prostaglandin_A2 <=> Prostaglandin_C2
|
not assigned
|
–
|
|
KEGG:
R05056
|
|
|
|
P1,P3-bis(5''-adenosyl)_triphosphate + H2O <=> H+ + AMP + ADP
|
3.1.4.1
phosphodiesterase I
3.6.1.17
bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)
3.6.1.29
bis(5'-adenosyl)-triphosphatase
3.6.1.41
bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
3.6.1.71
adenosine-5'-diphospho-5'-[DNA] diphosphatase
3.6.1.9
nucleotide diphosphatase
6.1.1.14
glycine---tRNA ligase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BR29527;
BS165343;
BS453422
KEGG:
R00187
MetaCyc:
BIS5-ADENOSYL-TRIPHOSPHATASE-RXN
SABIO-RK:
735
|
|
|
|
Stemmadenine <=> Catharanthine
|
not assigned
|
–
|
|
KEGG:
R05854
|
|
|
|
bithionol + H2O <=> H+ + 3-hydroxypropionate + CoA
|
3.1.2.4
3-hydroxyisobutyryl-CoA hydrolase
|
–
|
|
BRENDA:
BS446056
KEGG:
R03158
MetaCyc:
RXN-6384
SABIO-RK:
2990
|
|
|
|
Indole-3-acetaldehyde + O2 + H2O <=> H+ + indole-3-acetic_acid + H2O2
|
1.2.3.1
aldehyde oxidase
1.2.3.7
indole-3-acetaldehyde oxidase
|
–
–
|
|
BRENDA:
BR36791
KEGG:
R02681
MetaCyc:
INDOLE-3-ACETALDEHYDE-OXIDASE-RXN
SABIO-RK:
2576
|
|
|
|
NH3 + L-glutamate + ATP <=> H+ + L-glutamine + ADP + phosphate
|
6.3.1.2
glutamine synthetase
|
–
|
|
BRENDA:
BR6443
KEGG:
R00253
MetaCyc:
GLUTAMINESYN-RXN
SABIO-RK:
760
|
|
|
|
leukotriene_A4 + H2O <=> leukotriene_B4
|
3.3.2.6
leukotriene-A4 hydrolase
|
–
|
|
BRENDA:
BR48209
KEGG:
R03057
MetaCyc:
LEUKOTRIENE-A4-HYDROLASE-RXN
SABIO-RK:
2902
|
|
|
|
GDP-L-fucose + Sialyl-3-paragloboside <=> GDP + IV3NeuAc,III3Fuc-nLc4Cer
|
2.4.1
2.4.1.65
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase
|
–
–
|
|
KEGG:
R06075
|
|
|
|
Se-methyl-L-selenocysteine + H2O <=> methylselenol + pyruvate + NH3
|
4.4.1.1
cystathionine gamma-lyase
4.4.1.11
methionine gamma-lyase
4.4.1.13
cysteine-S-conjugate beta-lyase
|
–
–
–
|
|
BRENDA:
BS412866
KEGG:
R09366
MetaCyc:
RXN-11063
|
|
|
|
O2 + (S)-reticuline <=> H+ + H2O2 + (S)-scoulerine
|
1.21.3.3
reticuline oxidase
|
–
|
|
BRENDA:
BR36965
KEGG:
R03831
MetaCyc:
RETICULINE-OXIDASE-RXN
|
|
|
|
4-hydroxy-6-methylpretetramide + NADPH + O2 + H+ <=> 4-de(dimethylamino)-4-oxoanhydrotetracycline + NADP+ + H2O
|
1.14.13.233
4-hydroxy-6-methylpretetramide 12a-monooxygenase
|
–
|
|
BRENDA:
BR51808
KEGG:
R05462
MetaCyc:
RXN-17980
|
|
|
|
2-oxoglutaryl-CoA + H2O <=> H+ + 2-oxoglutarate + CoA
|
3.1.2
|
–
|
|
KEGG:
R10210
MetaCyc:
RXN-13098
|
|
|
|
alpha-D-glucose + ADP <=> alpha-D-glucose_6-phosphate + AMP
|
2.7.1.147
ADP-specific glucose/glucosamine kinase
|
–
|
|
KEGG:
R09085
|
|
|
|
(+)-citramalate <=> pyruvate + acetate
|
4.1.3.1
isocitrate lyase
4.1.3.22
citramalate lyase
|
–
–
|
|
BRENDA:
BR3370
KEGG:
R00325
MetaCyc:
CITRAMALATE-LYASE-RXN
|
|
|
|
L-proline + a_quinone <=> L-pyrroline-5-carboxylate + a_quinol
|
1.5.5.2
proline dehydrogenase
1.5.99.B2
|
–
–
|
|
BRENDA:
BR36918
KEGG:
R01253
|
|
|
|
1-phosphatidyl-1D-myo-inositol_3,5-bisphosphate + H2O <=> 1-phosphatidyl-1D-myo-inositol_5-phosphate + phosphate
|
3.1.3
3.1.3.36
phosphoinositide 5-phosphatase
3.1.3.56
inositol-polyphosphate 5-phosphatase
3.1.3.95
phosphatidylinositol-3,5-bisphosphate 3-phosphatase
|
–
–
–
–
|
|
BRENDA:
BR50989;
BS380869
KEGG:
R10928;
R12124
MetaCyc:
RXN-10938;
RXN-10958
SABIO-RK:
14198
|
|
|
|
D-ribose_5-phosphate + Uracil <=> H2O + pseudouridine_5''-phosphate
|
4.2.1.70
pseudouridylate synthase
|
–
|
|
BRENDA:
BR447
KEGG:
R01055
MetaCyc:
RXN0-5398
|
|
|
|
S-adenosyl-L-methionine + magnesium_protoporphyrin_monomethyl_ester + H2O <=> 131-hydroxy-magnesium-protoporphyrin_IX_13-monomethyl_ester + 5''-deoxyadenosine + L-methionine + H+
|
1.21.98.3
anaerobic magnesium-protoporphyrin IX monomethyl ester cyclase
|
–
|
|
BRENDA:
BR51845
KEGG:
R06268
MetaCyc:
RXN-8797
|
|
|
|
(R)-2-Aza-beta-tyrosyl-[pcp] + FADH2 + Cl- + O2 + H+ <=> (R)-2-Aza-3-chloro-beta-tyrosyl-[pcp] + FAD + 2 H2O
|
1.14.19
|
–
|
|
KEGG:
R11393
|
|
|
|
glycine + tetrahydrofolate + NAD+ <=> 5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH
|
1.4.1.f
1.4.4.2
glycine dehydrogenase (aminomethyl-transferring)
1.8.1.4
dihydrolipoyl dehydrogenase
2.1.2.10
aminomethyltransferase
|
–
–
–
–
|
|
KEGG:
R01221
MetaCyc:
GCVMULTI-RXN
SABIO-RK:
1451
|
|
|
|
N-formylanthranilic_acid + H2O <=> formate + anthranilate
|
3.5.1.9
arylformamidase
|
–
|
|
BRENDA:
BS140693
KEGG:
R00988
|
|
|
|
coniferyl_alcohol + NADP+ <=> coniferyl_aldehyde + NADPH + H+
|
1.1.1.194
coniferyl-alcohol dehydrogenase
1.1.1.195
cinnamyl-alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.90
aryl-alcohol dehydrogenase
1.1.1.91
aryl-alcohol dehydrogenase (NADP+)
|
–
–
–
–
–
|
|
BRENDA:
BR36707
KEGG:
R02593
MetaCyc:
RXN-2602
SABIO-RK:
2499
|
|
|
|
(2S,5S)-5-carboxymethylproline + ATP <=> H+ + (3S,5S)-carbapenam_3-carboxylate + AMP + diphosphate
|
6.3.3.6
carbapenam-3-carboxylate synthase
|
–
|
|
BRENDA:
BR50731
KEGG:
R10556
MetaCyc:
RXN-8948
|
|
|
|
Hypotaurine + H2O + NAD+ <=> taurine + NADH + H+
|
1.8.1.3
hypotaurine dehydrogenase
|
–
|
|
BRENDA:
BR37006
KEGG:
R01681
MetaCyc:
HYPOTAURINE-DEHYDROGENASE-RXN
|
|
|
|
1-butanol + NADP+ <=> H+ + Butyraldehyde + NADPH
|
1.1.1
1.1.1.1
alcohol dehydrogenase
1.1.1.183
geraniol dehydrogenase (NADP+)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.188
prostaglandin-F synthase
1.1.1.191
indole-3-acetaldehyde reductase (NADPH)
1.1.1.195
cinnamyl-alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.21
aldose reductase
1.1.1.265
3-methylbutanal reductase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
1.1.1.72
glycerol dehydrogenase (NADP+)
1.1.1.91
aryl-alcohol dehydrogenase (NADP+)
|
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS165070;
BS439276-a
KEGG:
R03545
MetaCyc:
ENZRXN-201-RXN
SABIO-RK:
3329
|
|
|
|
H2O + agmatine <=> Urea + putrescine
|
3.5.3.1
arginase
3.5.3.11
agmatinase
|
–
–
|
|
BRENDA:
BR26108
KEGG:
R01157
MetaCyc:
AGMATIN-RXN
SABIO-RK:
595
|
|
|
|
protodeoxyviolaceinate + O2 + NADPH + H+ <=> protoviolaceinate + NADP+ + H2O
|
1.14.13.217
protodeoxyviolaceinate monooxygenase
1.14.13.224
violacein synthase
|
–
–
|
|
BRENDA:
BR51577
KEGG:
R11132;
R11134
MetaCyc:
RXN-13341;
RXN-13344
|
|
|
|
thiamine_diphosphate + H2O <=> H+ + thiamine_phosphate + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.100
thiamine phosphate phosphatase
3.1.3.2
acid phosphatase
3.6.1
3.6.1.15
nucleoside-triphosphate phosphatase
3.6.1.28
thiamine-triphosphatase
3.6.1.5
apyrase
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.6
nucleoside diphosphate phosphatase
|
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS141322;
BS141393
KEGG:
R00615;
R02092
MetaCyc:
RXN-14213;
RXN0-3542
SABIO-RK:
495;
9603
|
|
|
|
5,10-methenyltetrahydrofolate + H2O <=> 10-formyltetrahydrofolate + H+
|
3.5.4.9
methenyltetrahydrofolate cyclohydrolase
|
–
|
|
BRENDA:
BR22746
KEGG:
R01655
MetaCyc:
METHENYLTHFCYCLOHYDRO-RXN
SABIO-RK:
74
|
|
|
|
Epoxyethane + H2O <=> ethylene_glycol
|
3.3.2.10
soluble epoxide hydrolase
3.3.2.9
microsomal epoxide hydrolase
|
–
–
|
|
BRENDA:
BS405100
KEGG:
R05842
|
|
|
|
1,2-dihydroxynaphthalene + O2 <=> H+ + 2-hydroxy-2H-chromene-2-carboxylate
|
1.13.11.56
1,2-dihydroxynaphthalene dioxygenase
|
–
|
|
BRENDA:
BR49141
KEGG:
R04117
MetaCyc:
RXN-8612
SABIO-RK:
3841
|
|
|
|
L-valine + reduced_flavodoxin + O2 <=> N-hydroxy-L-valine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
|
BRENDA:
BR49381
KEGG:
R10031
|
|
|
|
Trichloroethylene + 2 H+ <=> cis-1,2-dichloroethene + Hydrochloric_acid
|
1.21.99.5
tetrachloroethene reductive dehalogenase
|
–
|
|
KEGG:
R05501
|
|
|
|
CMP-N-acetylneuraminate + ganglioside_GT1b <=> CMP + GQ1b
|
2.4.99
|
–
|
|
KEGG:
R05950
|
|
|
|
DMSO + H2O + NAD+ <=> dimethyl_sulfone + NADH + H+
|
1.8.1.17
dimethylsulfone reductase
|
–
|
|
BRENDA:
BR49576
KEGG:
R09498
MetaCyc:
RXN-9762
|
|
|
|
Avermectin_A1b_aglycone + dTDP-L-oleandrose <=> Avermectin_A1b_monosaccharide + dTDP
|
2.4.1
|
–
|
|
KEGG:
R06498
|
|
|
|
UDP-galactose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn
|
2.4.1
|
–
|
|
KEGG:
R09320
|
|
|
|
UDP-galactose + NORint <=> UDP + NOR2_antigen
|
2.4.1.228
lactosylceramide 4-alpha-galactosyltransferase
|
–
|
|
KEGG:
R11377
|
|
|
|
epsilon-N-biotinyl-L-lysine + 2 peptide <=> biotin-carboxyl-carrier_protein + 2 H2O
|
3.4
|
–
|
|
KEGG:
R04869
|
|
|
|
2-Phenylethylamine + H2O + acceptor <=> phenylacetaldehyde + NH3 + reduced_acceptor
|
1.4.9.1
methylamine dehydrogenase (amicyanin)
1.4.9.2
aralkylamine dehydrogenase (azurin)
1.4.98
|
–
–
–
|
|
BRENDA:
BS261184
KEGG:
R02612
MetaCyc:
RXN-11510
SABIO-RK:
2517
|
|
|
|
5-Oxoavermectin_''''1b''''_aglycone + NADPH + H+ <=> Avermectin_B1b_aglycone + NADP+
|
not assigned
|
–
|
|
KEGG:
R06475
|
|
|
|
S-adenosyl-L-methionine + 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)-tetracenomycin_C <=> 8-demethyl-8-(2,3,4-O-trimethyl-alpha-L-rhamnosyl)-tetracenomycin_C + S-adenosyl-L-homocysteine + H+
|
2.1.1.307
8-demethyl-8-(2,3-dimethoxy-alpha-L-rhamnosyl)tetracenomycin-C 4'-O-methyltransferase
|
–
|
|
BRENDA:
BR50859
KEGG:
R10958
MetaCyc:
RXN-15403
|
|
|
|
5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H+ <=> (R)-allantoin + CO2
|
not assigned
|
–
|
|
KEGG:
R06605
|
|
|
|
2-hydroxyethylphosphonate + NAD+ <=> phosphonoacetaldehyde + NADH + H+
|
1.1.1.309
phosphonoacetaldehyde reductase (NADH)
|
–
|
|
BRENDA:
BR49249
KEGG:
R09478
MetaCyc:
RXN-9009
|
|
|
|
dimethylallyl_diphosphate + adenine_in_tRNA <=> diphosphate + tRNA_containing_6-isopentenyladenosine
|
2.5.1.75
tRNA dimethylallyltransferase
|
–
|
|
KEGG:
R01122
|
|
|
|
(S)-3-sulfolactate + NAD+ <=> 3-sulfopyruvate + NADH + H+
|
1.1.1.272
D-2-hydroxyacid dehydrogenase (NADP+)
1.1.1.310
(S)-sulfolactate dehydrogenase
1.1.1.337
L-2-hydroxycarboxylate dehydrogenase (NAD+)
1.1.1.375
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
|
–
–
–
–
|
|
BRENDA:
BR49409
KEGG:
R05693
MetaCyc:
RXN-11689
SABIO-RK:
5289
|
|
|
|
obtusifoliol + reduced_flavodoxin + O2 <=> 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + flavin + H2O
|
1.14.14.154
sterol 14alpha-demethylase
|
–
|
|
BRENDA:
BS186733
KEGG:
R05731
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> (E)-alpha-bisabolene + diphosphate
|
4.2.3.38
alpha-bisabolene synthase
|
–
|
|
BRENDA:
BR49017
KEGG:
R08370
MetaCyc:
RXN-8550
|
|
|
|
dibenzo-p-dioxin + NADH + O2 <=> 2,2'',3-trihydroxybiphenyl_ether + NAD+
|
1.14.12
1.14.12.18
biphenyl 2,3-dioxygenase
1.14.12.22
carbazole 1,9a-dioxygenase
|
–
–
–
|
|
BRENDA:
BS376687
KEGG:
R05439
|
|
|
|
O2 + glutathione <=> GSSG + H2O2
|
1.8.3.2
thiol oxidase
1.8.3.3
glutathione oxidase
|
–
–
|
|
BRENDA:
BR37015
KEGG:
R00120
MetaCyc:
GLUTATHIONE-OXIDASE-RXN
|
|
|
|
CDP-3,6-dideoxy-D-glucose + NADP+ <=> CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + NADPH + H+
|
1.1.1.342
CDP-paratose synthase
|
–
|
|
BRENDA:
BR50235
KEGG:
R04265
MetaCyc:
RXN-9159
|
|
|
|
L-2-aminoadipate + L-cysteine + L-valine + ATP + H2O <=> H+ + N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + AMP + diphosphate
|
6.3.2.26
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
|
–
|
|
BRENDA:
BR40508
KEGG:
R04870
MetaCyc:
6.3.2.26-RXN
|
|
|
|
trimethylamine + coenzyme_M <=> methyl-CoM + Dimethylamine
|
2.1.1.247
[methyl-Co(III) methylamine-specific corrinoid protein]---coenzyme M methyltransferase
2.1.1.250
trimethylamine---corrinoid protein Co-methyltransferase
|
–
–
|
|
KEGG:
R09124
|
|
|
|
dTDP-L-olivose + NADP+ <=> dTDP-4-oxo-2,6-dideoxy-L-mannose + NADPH + H+
|
1.1.1
|
–
|
|
KEGG:
R06434
MetaCyc:
RXN-12929
|
|
|
|
2-methyl-4-amino-5-hydroxymethylpyrimidine_phosphate + ATP <=> 2-methyl-4-amino-5-hydroxymethylpyrimidine_diphosphate + ADP
|
2.7.1.49
hydroxymethylpyrimidine kinase
2.7.4.7
phosphooxymethylpyrimidine kinase
|
–
–
|
|
BRENDA:
BR48075
KEGG:
R04509
MetaCyc:
PYRIMSYN3-RXN
|
|
|
|
3-Oxo-3-ureidoisobutyrate + H2O <=> methylmalonate + Urea
|
3.5.1.95
N-malonylurea hydrolase
|
–
|
|
KEGG:
R10778
|
|
|
|
phosphate + maltose <=> beta-D-glucose_1-phosphate + D-glucose
|
2.4.1.8
maltose phosphorylase
|
–
|
|
BRENDA:
BR44251
KEGG:
R01555;
R06040
MetaCyc:
MALTOSE-PHOSPHORYLASE-RXN
|
|
|
|
(S)-scoulerine + reduced_flavodoxin + O2 <=> (S)-cheilanthifoline + flavin + 2 H2O
|
1.14.19.65
(S)-cheilanthifoline synthase
|
–
|
|
BRENDA:
BR37081
KEGG:
R03834
|
|
|
|
S-adenosyl-L-methionine + precorrin-2 <=> H+ + S-adenosyl-L-homocysteine + precorrin-3A
|
2.1.1.130
precorrin-2 C20-methyltransferase
|
–
|
|
BRENDA:
BR1453
KEGG:
R03948
MetaCyc:
2.1.1.130-RXN
|
|
|
|
N-acetyl-D-glucosamine_6-phosphate <=> N-acetyl-D-glucosamine_1-phosphate
|
5.4.2.2
phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)
5.4.2.3
phosphoacetylglucosamine mutase
5.4.2.8
phosphomannomutase
|
–
–
–
|
|
BRENDA:
BR19
KEGG:
R08193
MetaCyc:
PHOSACETYLGLUCOSAMINEMUT-RXN
SABIO-RK:
11321
|
|
|
|
N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate <=> anthranilate + 5-phospho-alpha-D-ribose_1-diphosphate
|
2.4.2.18
anthranilate phosphoribosyltransferase
|
–
|
|
BRENDA:
BR47560
KEGG:
R01073
MetaCyc:
PRTRANS-RXN
SABIO-RK:
1341
|
|
|
|
bithionol <=> acryloyl-CoA + H2O
|
4.2.1
4.2.1.116
3-hydroxypropionyl-CoA dehydratase
4.2.1.17
enoyl-CoA hydratase
|
–
–
–
|
|
BRENDA:
BR49125
KEGG:
R03045
MetaCyc:
RXN-6383
SABIO-RK:
2892
|
|
|
|
5beta-Pregnan-3alpha-ol-20-one + NADP+ <=> 5beta-pregnane-3,20-dione + NADPH
|
1.1.1.112
indanol dehydrogenase
1.1.1.149
20alpha-hydroxysteroid dehydrogenase
1.1.1.209
3(or 17)alpha-hydroxysteroid dehydrogenase
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
1.1.1.357
3alpha-hydroxysteroid 3-dehydrogenase
1.1.1.50
3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
1.3.1.20
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BS187016
KEGG:
R04846
SABIO-RK:
4491
|
|
|
|
Toluene + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> benzyl_alcohol + oxidized_ferredoxin + H2O
|
1.14.13
1.14.15.26
toluene methyl-monooxygenase
|
–
–
|
|
BRENDA:
BR52308
KEGG:
R02550
MetaCyc:
TOLUENE-SIDE-CHAIN-MONOOXYGENASE-RXN
|
|
|
|
2-oxoadipate + NH3 + NAD+ <=> 2-aminomuconate + NADH + H+ + H2O
|
1.5.1
|
–
|
|
KEGG:
R01937
|
|
|
|
CMP-beta-Kdo + lipid_IVA_(E._coli) <=> alpha-Kdo-(2rarr6)-lipid_IVA_(E._coli) + CMP + H+
|
2.4.99.12
lipid IVA 3-deoxy-D-manno-octulosonic acid transferase
2.4.99.13
(Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase
|
–
–
|
|
BRENDA:
BR49179;
BS402335;
BS423803
KEGG:
R04658
MetaCyc:
KDOTRANS-RXN
|
|
|
|
Emindole_SB + O2 + NADPH + H+ <=> 14,15-Epoxyemindole_SB + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R10351
MetaCyc:
RXN-15496
|
|
|
|
beta-tocopherol <=> alpha-tocopherol
|
not assigned
|
–
|
|
KEGG:
R07508
|
|
|
|
Cobalamin <=> hydroxycobalamin
|
not assigned
|
–
|
|
KEGG:
R00097
|
|
|
|
inositol_3,4,5,6-tetrakisphosphate + ATP <=> H+ + 1D-myo-inositol_1,3,4,5,6-pentakisphosphate + ADP
|
2.7.1.134
inositol-tetrakisphosphate 1-kinase
2.7.1.151
inositol-polyphosphate multikinase
2.7.1.159
inositol-1,3,4-trisphosphate 5/6-kinase
2.7.4.21
inositol-hexakisphosphate kinase
|
–
–
–
–
|
|
BRENDA:
BR47746;
BR48647
KEGG:
R03479;
R05801
MetaCyc:
2.7.1.134-RXN;
RXN-7162
SABIO-RK:
3273;
5392
|
|
|
|
melilotate + NAD+ <=> H+ + NADH + coumaric_acid
|
1.3.1.11
2-coumarate reductase
1.3.1.31
2-enoate reductase
|
–
–
|
|
BRENDA:
BR36796
KEGG:
R03709
MetaCyc:
COUMARATE-REDUCTASE-RXN
|
|
|
|
pentalenene + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> pentalen-13-al + H2O + oxidized_ferredoxin
|
1.14.15.32
pentalenene oxygenase
|
–
|
|
BRENDA:
BR49819
KEGG:
R09814
MetaCyc:
RXN-13400
|
|
|
|
dTDP-acarviose-7-phosphate <=> acarbose_7'''-phosphate
|
not assigned
|
–
|
|
KEGG:
R11248
|
|
|
|
2-oxobutyrate + CoA <=> propionyl-CoA + formate
|
2.3.1
2.3.1.54
formate C-acetyltransferase
|
–
–
|
|
BRENDA:
BS321064
KEGG:
R06987
MetaCyc:
KETOBUTFORMLY-RXN
|
|
|
|
a_very-long-chain_(3R)-3-hydroxyacyl-CoA + NADP+ <=> a_very-long-chain_3-oxoacyl-CoA + NADPH + H+
|
1.1.1.330
very-long-chain 3-oxoacyl-CoA reductase
|
–
|
|
BRENDA:
BR50139
KEGG:
R10826
|
|
|
|
N-Acetyl-N6,O-didemethylpuromycin-5''-phosphate + S-adenosyl-L-methionine <=> N-Acetyl-O-demethylpuromycin-5''-phosphate + S-adenosyl-L-homocysteine
|
2
|
–
|
|
KEGG:
R05674
|
|
|
|
paraxanthine <=> 5-Acetylamino-6-formylamino-3-methyluracil
|
2.3.1.5
arylamine N-acetyltransferase
|
–
|
|
KEGG:
R07940
|
|
|
|
4-Chloro-L-lysine + reduced_acceptor + O2 <=> 2-Amino-4-chloro-4-pentenoic_acid + acceptor + formaldehyde + NH3 + H2O
|
1.14.99
|
–
|
|
KEGG:
R12408
|
|
|
|
1-hydroxy-2-naphthaldehyde + pyruvate <=> (3E)-4-(1-hydroxynaphthalen-2-yl)-2-oxobut-3-enoate + H2O
|
4.1.2
4.1.2.45
trans-o-hydroxybenzylidenepyruvate hydratase-aldolase
|
–
–
|
|
BRENDA:
BS403235
KEGG:
R05648
|
|
|
|
imidazolinone + H2O <=> Formiminoglycine
|
3.5.2
|
–
|
|
KEGG:
R04026
MetaCyc:
R63-RXN
|
|
|
|
palmitoyl-[acyl-carrier_protein] + CoA <=> palmitoyl-CoA + [acyl-carrier_protein]
|
2.3.1
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
|
–
–
–
|
|
BRENDA:
BS456174
KEGG:
R10700
MetaCyc:
RXN3O-9780
|
|
|
|
2-methylacetoacetyl-CoA + CoA <=> propionyl-CoA + acetyl-CoA
|
2.3.1.16
acetyl-CoA C-acyltransferase
2.3.1.9
acetyl-CoA C-acetyltransferase
|
–
–
|
|
BRENDA:
BS407013
KEGG:
R00927
MetaCyc:
METHYLACETOACETYLCOATHIOL-RXN
|
|
|
|
1,3-dicarboxyurea + H+ <=> allophanate + CO2
|
not assigned
|
–
|
|
KEGG:
R12334
MetaCyc:
RXN-20064
|
|
|
|
H+ + glycine + succinyl-CoA <=> CO2 + CoA + 5-aminolevulinate
|
2.3.1.37
5-aminolevulinate synthase
|
–
|
|
BRENDA:
BR44037
KEGG:
R00830
MetaCyc:
5-AMINOLEVULINIC-ACID-SYNTHASE-RXN
|
|
|
|
(E,Z)-indolyl-3-acetaldoxime <=> Indole-3-acetaldehyde
|
1.7.3
|
–
|
|
KEGG:
R08606
|
|
|
|
D-tagatose_6-phosphate + ATP <=> H+ + D-tagatose_1,6-bisphosphate + ADP
|
2.7.1.11
6-phosphofructokinase
2.7.1.144
tagatose-6-phosphate kinase
2.7.1.56
1-phosphofructokinase
|
–
–
–
|
|
BRENDA:
BR47754
KEGG:
R03236
MetaCyc:
TAGAKIN-RXN
SABIO-RK:
3059
|
|
|
|
lycopene + reduced_acceptor + O2 <=> all-trans-3,4-didehydrolycopene + acceptor + H2O
|
1.3.99.30
phytoene desaturase (3,4-didehydrolycopene-forming)
|
–
|
|
KEGG:
R07518
|
|
|
|
2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O <=> Isobutyrate + 2-hydroxy-2,4-pentadienoate
|
3.7.1
|
–
|
|
KEGG:
R05364
|
|
|
|
(1R,2S,5S,6S)-2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate <=> (1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate + pyruvate
|
4.2.99.20
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
|
–
|
|
BRENDA:
BR48915
KEGG:
R08166
MetaCyc:
RXN-9310
|
|
|
|
nitrite + H2O + NADP+ <=> H+ + nitrate + NADPH
|
1.7.1.1
nitrate reductase (NADH)
1.7.1.2
nitrate reductase [NAD(P)H]
1.7.1.3
nitrate reductase (NADPH)
|
–
–
–
|
|
BRENDA:
BR22625
KEGG:
R00796
MetaCyc:
NITRATE-REDUCTASE-NADPH-RXN;
NITRATE-REDUCTASE-NADPORNOPH-RXN
|
|
|
|
palmitoyl-CoA + L-serine + H+ <=> 3-dehydrosphinganine + CO2 + CoA
|
2.3.1.50
serine C-palmitoyltransferase
|
–
|
|
BRENDA:
BR44052
KEGG:
R01281
MetaCyc:
SERINE-C-PALMITOYLTRANSFERASE-RXN
|
|
|
|
S-adenosyl-L-methionine + caffeic_acid <=> H+ + ferulic_acid + S-adenosyl-L-homocysteine
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
2.1.1.68
caffeate O-methyltransferase
|
–
–
|
|
BRENDA:
BR43911
KEGG:
R03366
MetaCyc:
RXN-1104
SABIO-RK:
14976
|
|
|
|
H2O + dTMP <=> phosphate + thymidine
|
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.31
nucleotidase
3.1.3.32
polynucleotide 3'-phosphatase
3.1.3.34
deoxynucleotide 3'-phosphatase
3.1.3.35
thymidylate 5'-phosphatase
3.1.3.5
5'-nucleotidase
3.1.3.89
5'-deoxynucleotidase
|
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR10688
KEGG:
R01569
MetaCyc:
THYMIDYLATE-5-PHOSPHATASE-RXN
SABIO-RK:
479
|
|
|
|
2-dehydro-3-deoxy-D-glucarate <=> pyruvate + tartronate_semialdehyde
|
4.1.2.20
2-dehydro-3-deoxyglucarate aldolase
|
–
|
|
BRENDA:
BR352
KEGG:
R03277
MetaCyc:
4.1.2.20-RXN
|
|
|
|
tRNAMet + L-glutamate + ATP <=> Glu-tRNAGln + diphosphate + AMP
|
6.1.1.17
glutamate---tRNA ligase
6.1.1.24
glutamate---tRNAGln ligase
|
–
–
|
|
KEGG:
R05578
|
|
|
|
dihomocitrate <=> (-)-threo-iso(homo)2citrate
|
4.2.1.114
methanogen homoaconitase
|
–
|
|
KEGG:
R10391
|
|
|
|
gamma-tocotrienol <=> 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol
|
5.5.1.24
tocopherol cyclase
|
–
|
|
BRENDA:
BR50794;
BS427883
KEGG:
R10624
MetaCyc:
RXN-14922
|
|
|
|
beta-Ala-Arg + H2O <=> beta-Alanine + 2-amino-5-guanidinovalerate
|
3.4.13.18
cytosol nonspecific dipeptidase
3.4.13.4
Xaa-Arg dipeptidase
|
–
–
|
|
KEGG:
R03935
SABIO-RK:
3676
|
|
|
|
palmitoyl-CoA + NADP+ <=> trans-2-hexadecenoyl-CoA + NADPH + H+
|
1.3.1.38
trans-2-enoyl-CoA reductase (NADPH)
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
|
–
–
|
|
BRENDA:
BS258627
KEGG:
R01278
MetaCyc:
RXN-14194
SABIO-RK:
1494
|
|
|
|
S-adenosyl-L-methionine + Pretetramid <=> S-adenosyl-L-homocysteine + 6-methylpretetramide + H+
|
2.1.1
2.1.1.M31
|
–
–
|
|
KEGG:
R09189
MetaCyc:
RXN-17982
|
|
|
|
L-aspartate + NADP+ <=> iminosuccinate + NADPH + H+
|
1.4.1.21
aspartate dehydrogenase
|
–
|
|
KEGG:
R07407
|
|
|
|
dodecanoyl-[acyl-carrier_protein] + H2O <=> [acyl-carrier_protein] + laurate + H+
|
3.1.2.14
oleoyl-[acyl-carrier-protein] hydrolase
3.1.2.21
dodecanoyl-[acyl-carrier-protein] hydrolase
|
–
–
|
|
BRENDA:
BR2506;
BS12699
KEGG:
R04014
MetaCyc:
3.1.2.21-RXN
SABIO-RK:
3749
|
|
|
|
Maleamate + H2O <=> Maleate + NH3
|
3.5.1.107
maleamate amidohydrolase
|
–
|
|
BRENDA:
BR49201
KEGG:
R03540
MetaCyc:
RXN-646
SABIO-RK:
3324
|
|
|
|
ATP + formylglycinamide_ribonucleotide + L-glutamine + H2O <=> H+ + L-glutamate + ADP + phosphate + 2-(formamido)-N1-(5-phosphoribosyl)acetamidine
|
6.3.5.3
phosphoribosylformylglycinamidine synthase
|
–
|
|
BRENDA:
BR150
KEGG:
R04463
MetaCyc:
FGAMSYN-RXN
|
|
|
|
Hydrogenobyrinate + L-glutamine + ATP + H2O <=> H+ + L-glutamate + hydrogenobyrinic_acid_a,c-diamide + ADP + phosphate
|
6.3.5.11
cobyrinate a,c-diamide synthase
6.3.5.9
hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing)
|
–
–
|
|
BRENDA:
BR48014
KEGG:
R05224
MetaCyc:
R341-RXN
SABIO-RK:
4835
|
|
|
|
Hydroiodic_acid + 3,5-diiodo-L-tyrosine <=> 3-iodo-L-tyrosine + Iodine
|
1.11.1.8
iodide peroxidase
|
–
|
|
KEGG:
R03973
|
|
|
|
(3S)-citryl-CoA <=> oxaloacetate + acetyl-CoA
|
4.1.3.34
citryl-CoA lyase
|
–
|
|
BRENDA:
BR3376
KEGG:
R00354
MetaCyc:
RXN-7929
|
|
|
|
L-serine + indole <=> L-tryptophan + H2O
|
4.1.99.1
tryptophanase
4.2.1.122
tryptophan synthase (indole-salvaging)
4.2.1.20
tryptophan synthase
|
–
–
–
|
|
BRENDA:
BR49621
KEGG:
R00674
MetaCyc:
RXN0-2382
SABIO-RK:
1054
|
|
|
|
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> 2-hydroxy-5-methyl-1-naphthoate + CoA + CO2 + H2O + NADP+
|
2.3.1.237
neocarzinostatin naphthoate synthase
|
–
|
|
BRENDA:
BR51201
KEGG:
R11125
MetaCyc:
RXN-15689
|
|
|
|
D-ornithine <=> 2,4-Diaminopentanoate
|
5.4.3.5
D-ornithine 4,5-aminomutase
|
–
|
|
BRENDA:
BR29
KEGG:
R02461
MetaCyc:
ORNMUTST-RXN
|
|
|
|
S-adenosyl-L-methionine + 2-methoxy-6-polyprenyl-1,4-benzoquinol <=> 6-methoxy-3-methyl-2-all-trans-polyprenyl-1,4-benzoquinol + S-adenosyl-L-homocysteine + H+
|
2.1.1.201
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase
|
–
|
|
BRENDA:
BR49307;
BS410184
KEGG:
R09737
MetaCyc:
RXN-11754
|
|
|
|
5-amino-2,6-dioxy-4-(5'-phosphoribitylamino)pyrimidine + H2O <=> 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + phosphate
|
3.1.3.104
5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase
|
–
|
|
BRENDA:
BR51773
KEGG:
R07280
MetaCyc:
RIBOPHOSPHAT-RXN
SABIO-RK:
8920
|
|
|
|
UDP-N-acetyl-D-galactosamine + Globotetraosylceramide <=> GalNAc-alpha-1,3-GalNAc-beta-1,3-Gal-alpha-1,4-Gal-beta-1,4-Glc-beta-1,1-ceramide + H+ + UDP
|
2.4.1.88
globoside alpha-N-acetylgalactosaminyltransferase
|
–
|
|
BRENDA:
BS452152
KEGG:
R04182;
R05965
MetaCyc:
2.4.1.88-RXN
|
|
|
|
protoporphyrinogen-IX + 3 acceptor <=> protoporphyrin_IX + 3 reduced_acceptor
|
1.3.99
|
–
|
|
KEGG:
R12605
|
|
|
|
an_alcohol + NAD+ <=> an_aldehyde + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.103
L-threonine 3-dehydrogenase
1.1.1.11
D-arabinitol 4-dehydrogenase
1.1.1.14
L-iditol 2-dehydrogenase
1.1.1.17
mannitol-1-phosphate 5-dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.192
long-chain-alcohol dehydrogenase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.202
1,3-propanediol dehydrogenase
1.1.1.21
aldose reductase
1.1.1.244
methanol dehydrogenase
1.1.1.245
cyclohexanol dehydrogenase
1.1.1.284
S-(hydroxymethyl)glutathione dehydrogenase
1.1.1.306
S-(hydroxymethyl)mycothiol dehydrogenase
1.1.1.307
D-xylose reductase
1.1.1.6
glycerol dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
1.1.1.73
octanol dehydrogenase
1.1.1.77
lactaldehyde reductase
1.1.1.78
methylglyoxal reductase (NADH)
1.1.1.80
isopropanol dehydrogenase (NADP+)
1.1.1.B4
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR29164;
BS139564;
BS405084
KEGG:
R00623;
R00754;
R07326
MetaCyc:
ALCOHOL-DEHYDROG-GENERIC-RXN;
ALCOHOL-DEHYDROG-RXN;
ALCOHOL-DEHYDROGENASE-NADP+-RXN_WOP
SABIO-RK:
597
|
|
|
|
L-ectoine + 2-oxoglutarate + O2 <=> 5-hydroxyectoine + succinate + CO2
|
1.14.11.55
ectoine hydroxylase
|
–
|
|
BRENDA:
BR51933
KEGG:
R08050
MetaCyc:
RXN-18394
|
|
|
|
N-acetyl-D-mannosamine_6-phosphate <=> N-acetyl-D-glucosamine_6-phosphate
|
5.1.3.9
N-acylglucosamine-6-phosphate 2-epimerase
|
–
|
|
BRENDA:
BS368626
KEGG:
R02087
MetaCyc:
NANE-RXN
|
|
|
|
UDP-N-acetyl-beta-L-fucosamine <=> UDP-2,6-dideoxy-2-acetamidino-beta-L-galactose
|
not assigned
|
–
|
|
KEGG:
R12584
|
|
|
|
CTP + N,N'-diacetyllegionaminate <=> CMP-N,N''-diacetyllegionaminate + diphosphate
|
2.7.7.82
CMP-N,N'-diacetyllegionaminic acid synthase
|
–
|
|
BRENDA:
BR50311
KEGG:
R10182
MetaCyc:
RXN-12239
|
|
|
|
UDP-N-acetyl-D-glucosamine + alpha-D-Man-1-Ser/Thr <=> UDP + beta-D-GlcNAc-(1->4)-alpha-D-Man-1-Ser/Thr
|
2.4.1.312
protein O-mannose beta-1,4-N-acetylglucosaminyltransferase
|
–
|
|
KEGG:
R11407
|
|
|
|
carboxynorspermidine + NADP+ + H2O <=> L-aspartate_4-semialdehyde + 1,3-diaminopropane + NADPH + H+
|
1.4.1.B4
1.5.1.43
carboxynorspermidine synthase
|
–
–
|
|
BRENDA:
BR49680
KEGG:
R09080
MetaCyc:
RXN-11565
SABIO-RK:
14726
|
|
|
|
carboxybiuret + H+ <=> Biuret + CO2
|
not assigned
|
–
|
|
KEGG:
R12335
MetaCyc:
RXN-20066
|
|
|
|
3-geranyl-4-hydroxybenzoate + H+ <=> 2-polyprenylphenol + CO2
|
4.1.1.98
4-hydroxy-3-polyprenylbenzoate decarboxylase
|
–
|
|
BRENDA:
BR51054
KEGG:
R04985
MetaCyc:
RXN-15309
|
|
|
|
tetrahydrofolate + acetyl-CoA <=> 5-methyltetrahydrofolate + CoA + CO
|
2.1.1.258
5-methyltetrahydrofolate---corrinoid/iron-sulfur protein Co-methyltransferase
2.3.1.169
CO-methylating acetyl-CoA synthase
|
–
–
|
|
KEGG:
R10243
|
|
|
|
ATP + citrate + L-glutamate <=> ADP + phosphate + beta-Citryl-L-glutamate + H+
|
6.3.1.17
beta-citrylglutamate synthase
6.3.2.B11
|
–
–
|
|
BRENDA:
BR50904
KEGG:
R10677
MetaCyc:
RXN-15266
|
|
|
|
(5Z,11Z,14Z)-8,9-epoxyeicosatrienoic_acid + H2O <=> (5Z,11Z,14Z)-8,9-dihydroxyeicosa-5,11,14-trienoic_acid
|
3.3.2.10
soluble epoxide hydrolase
3.3.2.9
microsomal epoxide hydrolase
|
–
–
|
|
BRENDA:
BS403048
KEGG:
R07110
|
|
|
|
benzoylformate + CoA + NAD+ <=> benzoyl-CoA + CO2 + NADH
|
1.2.1.58
phenylglyoxylate dehydrogenase (acylating)
1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
|
–
–
|
|
BRENDA:
BR1124
KEGG:
R02450
MetaCyc:
1.2.1.58-RXN
|
|
|
|
4-N-trimethylaminobutyraldehyde + NAD+ + H2O <=> gamma-butyrobetaine + NADH + H+
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.47
4-trimethylammoniobutyraldehyde dehydrogenase
1.2.1.8
betaine-aldehyde dehydrogenase
|
–
–
–
|
|
BRENDA:
BR29407
KEGG:
R03283
MetaCyc:
1.2.1.47-RXN
SABIO-RK:
3102
|
|
|
|
NADP+ + bilirubin <=> Biliverdin + NADPH + H+
|
1.3.1.24
biliverdin reductase
|
–
|
|
BRENDA:
BR40361
KEGG:
R02393
MetaCyc:
BILIVERDIN-REDUCTASE-RXN
SABIO-RK:
2334
|
|
|
|
2-aminobenzoyl-CoA + malonyl-CoA + H+ <=> 4-hydroxy-2-methylquinoline + CoA + CO2
|
2.3.1
|
–
|
|
KEGG:
R12049
MetaCyc:
RXN-15021
|
|
|
|
ent-kaur-16-en-19-al + reduced_flavodoxin + O2 <=> ent-kaur-16-en-19-oate + flavin + H2O
|
1.14.14.86
ent-kaurene monooxygenase
|
–
|
|
BRENDA:
BR40527
KEGG:
R06293
|
|
|
|
acetyl-CoA + dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose <=> CoA + dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactopyranose + H+
|
2.3.1.197
dTDP-3-amino-3,6-dideoxy-alpha-D-galactopyranose 3-N-acetyltransferase
|
–
|
|
BRENDA:
BR49889
KEGG:
R09873
MetaCyc:
RXN-12806
|
|
|
|
L-tyrosine + O2 <=> L-Dopa
|
1.10.3.1
catechol oxidase
1.14.18.1
tyrosinase
|
–
–
|
|
BRENDA:
BR50166
KEGG:
R00031;
R00731
MetaCyc:
RXN-5861
SABIO-RK:
1094;
622
|
|
|
|
iminosuccinate + dihydroxyacetone_phosphate <=> quinolinic_acid + H2O + phosphate
|
2.5.1.72
quinolinate synthase
|
–
|
|
BRENDA:
BR48966
KEGG:
R04292
MetaCyc:
QUINOLINATE-SYNTHA-RXN
|
|
|
|
alpha-D-glucose_1-phosphate + UTP + H+ <=> UDP-glucose + diphosphate
|
2.7.7.23
UDP-N-acetylglucosamine diphosphorylase
2.7.7.24
glucose-1-phosphate thymidylyltransferase
2.7.7.28
nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase
2.7.7.33
glucose-1-phosphate cytidylyltransferase
2.7.7.64
UTP-monosaccharide-1-phosphate uridylyltransferase
2.7.7.9
UTP---glucose-1-phosphate uridylyltransferase
|
–
–
–
–
–
–
|
|
BRENDA:
BR47905;
BR48768;
BS383404
KEGG:
R00289;
R08845
MetaCyc:
GLUC1PURIDYLTRANS-RXN
SABIO-RK:
68;
8973
|
|
|
|
2-Carboxy-2,3-dihydro-5,6-dihydroxyindole + dopaquinone <=> L-Dopachrome + L-Dopa
|
not assigned
|
–
|
|
KEGG:
R03672
MetaCyc:
RXN-11369
|
|
|
|
phosphoribulosylformimino-AICAR-phosphate + L-glutamine <=> H+ + L-glutamate + D-erythro-1-(imidazol-4-yl)glycerol_3-phosphate + 5-aminoimidazole-4-carboxamide_ribonucleotide
|
2.4.2
4.3.1.B2
4.3.2.10
imidazole glycerol-phosphate synthase
|
–
–
–
|
|
BRENDA:
BR51141;
BR52465
KEGG:
R04558
MetaCyc:
GLUTAMIDOTRANS-RXN
SABIO-RK:
4234
|
|
|
|
L-arabinose + NADP+ <=> L-arabinono-1,4-lactone + NADPH + H+
|
1.1.1.120
galactose 1-dehydrogenase (NADP+)
1.1.1.179
D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.376
L-arabinose 1-dehydrogenase [NAD(P)+]
1.1.1.46
L-arabinose 1-dehydrogenase
|
–
–
–
–
|
|
BRENDA:
BR51098;
BS187101
KEGG:
R10787
SABIO-RK:
14861
|
|
|
|
indole <=> indole-3-acetic_acid
|
2.5.1
|
–
|
|
KEGG:
R08609
|
|
|
|
tetracenomycin_A2 + O2 + NADPH + H+ <=> tetracenomycin_C + H2O + NADP+
|
1.14.13.200
tetracenomycin A2 monooxygenase-dioxygenase
|
–
|
|
BRENDA:
BR51077
KEGG:
R06704
MetaCyc:
RXN-15434
|
|
|
|
S-adenosyl-L-methionine + demethyldecarbamoylnovobiocin <=> S-adenosyl-L-homocysteine + decarbamoylnovobiocin + H+
|
2.1.1.285
demethyldecarbamoylnovobiocin O-methyltransferase
|
–
|
|
BRENDA:
BR50631
KEGG:
R06771
MetaCyc:
RXN-14545
|
|
|
|
3-[(2S,5R)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]-2-oxopropanoate + L-phenylalanine <=> L-dihydroanticapsin + phenylpyruvate
|
2.6.1
|
–
|
|
KEGG:
R11068
MetaCyc:
RXN-16297
|
|
|
|
O-phospho-L-serine + H2O <=> L-serine + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.15
histidinol-phosphatase
3.1.3.16
protein-serine/threonine phosphatase
3.1.3.2
acid phosphatase
3.1.3.20
phosphoglycerate phosphatase
3.1.3.26
4-phytase
3.1.3.29
N-acylneuraminate-9-phosphatase
3.1.3.3
phosphoserine phosphatase
3.1.3.48
protein-tyrosine-phosphatase
3.1.3.75
phosphoethanolamine/phosphocholine phosphatase
3.1.3.8
3-phytase
|
–
–
–
–
–
–
–
–
–
–
–
|
|
BRENDA:
BS364502
KEGG:
R00582
MetaCyc:
RXN0-5114
SABIO-RK:
10330;
983
|
|
|
|
pectate + H2O <=> D-galacturonate + pectate
|
3.2.1.15
endo-polygalacturonase
3.2.1.67
galacturonan 1,4-alpha-galacturonidase
|
–
–
|
|
KEGG:
R01982
|
|
|
|
(S)-3-hydroxyoctanoyl-CoA + NAD+ <=> 3-oxooctanoyl-CoA + NADH + H+
|
1.1.1.211
long-chain-3-hydroxyacyl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
|
BRENDA:
BS188060
KEGG:
R04745
MetaCyc:
RXN-20679
SABIO-RK:
4401
|
|
|
|
octanoyl-[acyl-carrier_protein] + Lipoyl-carrier_protein_E2 <=> [Lipoyl-carrier_protein_E2]-N6-octanoyl-L-lysine + [acyl-carrier_protein]
|
2.3.1.181
lipoyl(octanoyl) transferase
|
–
|
|
KEGG:
R12427
|
|
|
|
Dimethylsulfide + O2 + NADH + H+ <=> methanethiol + formaldehyde + H2O + NAD+
|
1.14.13.131
dissimilatory dimethyl sulfide monooxygenase
|
–
|
|
BRENDA:
BR49804
KEGG:
R09786
MetaCyc:
RXN-9740
|
|
|
|
choloyl-CoA + taurine <=> H+ + taurocholate + CoA
|
2.3.1.65
bile acid-CoA:amino acid N-acyltransferase
|
–
|
|
BRENDA:
BS321166
KEGG:
R03720
MetaCyc:
RXN-9800
SABIO-RK:
3481
|
|
|
|
3-Amino-4-hydroxybenzoic_acid + N-acetyl-L-cysteine + O2 + H+ <=> grixazone_B + H2O + CO2
|
1.10.3.15
grixazone synthase
|
–
|
|
BRENDA:
BR51024
KEGG:
R10720
MetaCyc:
RXN-15414
|
|
|
|
L-3-hydroxykynurenine + H2O <=> H+ + 3-Hydroxyanthranilate + L-alanine
|
3.7.1.3
kynureninase
|
–
|
|
BRENDA:
BS190196
KEGG:
R02668
MetaCyc:
3-HYDROXY-KYNURENINASE-RXN
SABIO-RK:
12038;
2564
|
|
|
|
fluorene + O2 + NADH + H+ <=> 9-fluorenol + H2O + NAD+
|
1.14.12
1.14.12.12
naphthalene 1,2-dioxygenase
1.14.12.22
carbazole 1,9a-dioxygenase
1.14.13
|
–
–
–
–
|
|
BRENDA:
BS412059-a
KEGG:
R05422
MetaCyc:
FLUORENE-OXYGENASE-RXN
|
|
|
|
beta-cryptoxanthin + O2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> zeaxanthin + H2O + oxidized_ferredoxin
|
1.14
1.14.13
1.14.15.24
beta-carotene 3-hydroxylase
|
–
–
–
|
|
BRENDA:
BR49603
KEGG:
R07559
MetaCyc:
RXN-8026
|
|
|
|
formate + acetyl-CoA <=> pyruvate + CoA
|
2.3.1.54
formate C-acetyltransferase
|
–
|
|
BRENDA:
BR44056
KEGG:
R00212
MetaCyc:
PYRUVFORMLY-RXN
SABIO-RK:
146
|
|
|
|
Toluene + O2 + NADH + H+ <=> (1S,2R)-3-Methylcyclohexa-3,5-diene-1,2-diol + NAD+
|
1.14.12.11
toluene dioxygenase
|
–
|
|
BRENDA:
BR40532
KEGG:
R03559
MetaCyc:
TOLUENE-DIOXYGENASE-RXN
|
|
|
|
phosphatidylglycerol + phosphatidylglycerol <=> cardiolipin + glycerol
|
2.7.8
2.7.8.B10
|
–
–
|
|
BRENDA:
BR51129
KEGG:
R07390
|
|
|
|
D-erythro-3-Methylmalate + NAD+ <=> 2-oxobutyrate + CO2 + NADH
|
1.1.1
1.1.1.85
3-isopropylmalate dehydrogenase
|
–
–
|
|
KEGG:
R00994
MetaCyc:
RXN-7745
|
|
|
|
S-adenosyl-L-methionine + phenazine-1-carboxylic_acid <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine
|
2.1.1.327
phenazine-1-carboxylate N-methyltransferase
|
–
|
|
BRENDA:
BR51748
KEGG:
R11533
MetaCyc:
RXN-11897
|
|
|
|
(-)-threo-iso(homo)3citrate + NAD+ <=> 2-Oxosuberate + CO2 + NADH
|
1.1.1
|
–
|
|
KEGG:
R08215
MetaCyc:
R218-RXN
|
|
|
|
6-Oxocampestanol + O2 + NADPH <=> Cathasterone + NADP+ + H2O
|
1.14.13
|
–
|
|
KEGG:
R07430
|
|
|
|
NADP+ + 4-hydroxybutyrate <=> H+ + NADPH + succinate_semialdehyde
|
1.1.1
1.1.1.19
glucuronate reductase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.26
glyoxylate reductase
1.1.1.61
4-hydroxybutyrate dehydrogenase
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.B47
1.1.1.co
|
–
–
–
–
–
–
–
–
|
|
BRENDA:
BR51069
KEGG:
R09281
MetaCyc:
RXN-11002
SABIO-RK:
10705
|
|
|
|
UDP-N-acetyl-D-galactosaminuronic_acid + ATP + L-glutamine + H2O <=> UDP-2-acetamido-2-deoxy-alpha-D-galacturonamide + AMP + L-glutamate + diphosphate
|
6.3.5
|
–
|
|
KEGG:
R12590
|
|
|
|
nicotinamide + H2O <=> NH3 + nicotinate
|
3.5.1.13
aryl-acylamidase
3.5.1.19
nicotinamidase
3.5.1.4
amidase
|
–
–
–
|
|
BRENDA:
BR26099
KEGG:
R01268
MetaCyc:
NICOTINAMID-RXN
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-4-dehydro-beta-L-rhamnose
|
5.1.3.13
dTDP-4-dehydrorhamnose 3,5-epimerase
|
–
|
|
BRENDA:
BR188
KEGG:
R06514
MetaCyc:
DTDPDEHYDRHAMEPIM-RXN
SABIO-RK:
2651
|
|
|
|
DELTA5,7-avenasterol <=> isofucosterol
|
1.3.1.21
7-dehydrocholesterol reductase
|
–
|
|
KEGG:
R07487
|
|
|
|
O2 + H2O + putrescine <=> NH3 + H2O2 + 4-Aminobutyraldehyde
|
1.4.3.10
putrescine oxidase
1.4.3.21
primary-amine oxidase
1.4.3.22
diamine oxidase
|
–
–
–
|
|
BRENDA:
BR37068
KEGG:
R01151
MetaCyc:
PUTRESCINE-OXIDASE-RXN
SABIO-RK:
1392
|
|
|
|
(3R)-3-hydroxyhexanoyl-[acyl-carrier_protein] <=> trans-Hex-2-enoyl-[acp] + H2O
|
2.3.1
2.3.1.85
fatty-acid synthase system
2.3.1.86
fatty-acyl-CoA synthase system
4.2.1
4.2.1.59
3-hydroxyacyl-[acyl-carrier-protein] dehydratase
|
–
–
–
–
–
|
|
KEGG:
R04954
|
|
|
|
trans-3-Chloroallyl_aldehyde + H2O <=> trans-3-Chloroacrylic_acid + 2 H+
|
1.2.1.3
aldehyde dehydrogenase (NAD+)
|
–
|
|
KEGG:
R05237
|
|
|
|
5-carboxymethyl-2-hydroxymuconate_semialdehyde + NAD+ + H2O <=> H+ + 5-Carboxymethyl-2-hydroxymuconate + NADH
|
1.1.1.312
2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase
1.2.1.60
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
|
–
–
|
|
BRENDA:
BR29416
KEGG:
R04418
MetaCyc:
CHMS-DEHYDROGENASE-RXN
SABIO-RK:
4105
|
|
|
|
theophylline + NADPH + O2 + H+ <=> 1-Methylxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.179
methylxanthine N3-demethylase
|
–
|
|
KEGG:
R07976
MetaCyc:
RXN-13110
|
|
|
|
CMP-N-acetylneuraminate + GM1b <=> CMP + GD1a
|
not assigned
|
–
|
|
KEGG:
R05959
|
|
|
|
seleno-L-homocysteine + 5-methyltetrahydropteroyl-gamma-glutamyl-gamma-glutamylglutamate <=> seleno-L-methionine + tetrahydropteroyl-Glu3
|
2.1.1.13
methionine synthase
2.1.1.14
5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
|
–
–
|
|
KEGG:
R09365
MetaCyc:
RXN-12730
|
|
|
|
O-phospho-L-serine + 2-oxoglutarate <=> L-glutamate + 3-phosphohydroxypyruvate
|
2.6.1.52
phosphoserine transaminase
|
–
|
|
BRENDA:
BR47699
KEGG:
R04173
MetaCyc:
PSERTRANSAM-RXN
SABIO-RK:
3893
|
|
|
|
2 glutathione + protein_disulfide <=> GSSG + protein-dithiol
|
1.8.4.2
protein-disulfide reductase (glutathione)
|
–
|
|
BRENDA:
BR37013
KEGG:
R03915
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-4-dehydro-6-deoxy-alpha-D-gulose
|
5.1.3.27
dTDP-4-dehydro-6-deoxy-D-glucose 3-epimerase
|
–
|
|
BRENDA:
BR50724
KEGG:
R06437
MetaCyc:
RXN-14707
|
|
|
|
phosphatidylglycerol + phosphatidylethanolamine <=> cardiolipin + ethanolamine
|
2.7.8
2.7.8.B11
|
–
–
|
|
BRENDA:
BR51130
KEGG:
R11062
|
|
|
|
beta-D-ribosylnicotinate + ATP <=> H+ + nicotinic_acid_mononucleotide + ADP
|
2.7.1.173
nicotinate riboside kinase
|
–
|
|
BRENDA:
BR50054
KEGG:
R03347
MetaCyc:
RXN-8443
|
|
|
|
oxalosuccinate + H+ <=> 2-oxoglutarate + CO2
|
1.1.1.42
isocitrate dehydrogenase (NADP+)
|
–
|
|
BRENDA:
BR48779
KEGG:
R00268
MetaCyc:
RXN-8642
SABIO-RK:
241
|
|
|
|
N-formyl-L-kynurenine + H2O <=> L-kynurenine + formate + H+
|
3.5.1.9
arylformamidase
|
–
|
|
BRENDA:
BR22715
KEGG:
R01959
MetaCyc:
ARYLFORMAMIDASE-RXN
SABIO-RK:
2006
|
|
|
|
GDP-L-fucose + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> GDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-1-Asn
|
2.4.1.214
glycoprotein 3-alpha-L-fucosyltransferase
|
–
|
|
KEGG:
R09318
|
|
|
|
5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+
|
1.3.1.25
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
|
–
|
|
KEGG:
R08112
|
|
|
|
ATP + acetate <=> ADP + acetyl_phosphate
|
2.1.2.2
phosphoribosylglycinamide formyltransferase
2.7.2.1
acetate kinase
2.7.2.15
propionate kinase
2.7.2.2
carbamate kinase
|
–
–
–
–
|
|
BRENDA:
BR47820
KEGG:
R00315
MetaCyc:
ACETATEKIN-RXN
SABIO-RK:
71
|
|
|
|
UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate <=> UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate
|
2.6.1.87
UDP-4-amino-4-deoxy-L-arabinose aminotransferase
2.6.1.92
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase
|
–
–
|
|
BRENDA:
BR49185
KEGG:
R07659
MetaCyc:
RXN0-1863
|
|
|
|
geranylgeranyl_diphosphate <=> diphosphate + casbene
|
4.2.3.8
casbene synthase
|
–
|
|
BRENDA:
BR48355
KEGG:
R02064
MetaCyc:
CASBENE-SYNTHASE-RXN
|
|
|
|
D-mannose_6-phosphate <=> beta-D-fructose_6-phosphate
|
5.3.1.8
mannose-6-phosphate isomerase
5.3.1.9
glucose-6-phosphate isomerase
|
–
–
|
|
BRENDA:
BR239
KEGG:
R00772;
R01819
MetaCyc:
MANNPISOM-RXN
SABIO-RK:
1124
|
|
|
|
formaldehyde + H2O <=> methanol + formate + H+
|
1.2.98.1
formaldehyde dismutase
|
–
|
|
BRENDA:
BR36794
KEGG:
R00614
MetaCyc:
RXN-11453
|
|
|
|
(2E,6E)-farnesyl_diphosphate <=> pentalenene + diphosphate
|
4.2.3.7
pentalenene synthase
|
–
|
|
BRENDA:
BR48354
KEGG:
R02305
MetaCyc:
PENTALENENE-SYNTHASE-RXN
|
|
|
|
2 3-Hydroxyanthranilate + 4 O2 <=> Cinnabarinic_acid + 2 O2- + 2 H2O2 + 2 H+
|
1.11.1.21
catalase-peroxidase
1.11.1.6
catalase
|
–
–
|
|
KEGG:
R02670
|
|
|
|
L-2-aminoadipate_adenylate + Holo-Lys2 <=> alpha-Aminoadipoyl-S-acyl_enzyme + AMP
|
1.2.1.95
L-2-aminoadipate reductase
|
–
|
|
KEGG:
R04863
|
|
|
|
6-Hydroxynicotinate + NADH + H+ + O2 <=> 2,5-dihydroxypyridine + NAD+ + CO2 + H2O
|
1.14.13.114
6-hydroxynicotinate 3-monooxygenase
|
–
|
|
BRENDA:
BR49148
KEGG:
R08764
MetaCyc:
RXN-7573
|
|
|
|
L-fuconolactone + H2O <=> L-fuconate
|
3.1.1
|
–
|
|
KEGG:
R10689
|
|
|
|
methanol + coenzyme_M <=> methyl-CoM + H2O
|
2.1.1.246
[methyl-Co(III) methanol-specific corrinoid protein]---coenzyme M methyltransferase
2.1.1.90
methanol---corrinoid protein Co-methyltransferase
|
–
–
|
|
KEGG:
R09098
MetaCyc:
MTAMBARKMULTI-RXN
|
|
|
|
dTDP-4-ethylamino-3-O-methyl-2,4-dideoxy-L-threo-pentopyranose + Calicheamicin_PsAg <=> dTDP + Calicheamicin_alpha1(I)
|
2.4.2
|
–
|
|
KEGG:
R11420
|
|
|
|
2-dehydro-3-deoxy-D-galactonate_6-phosphate <=> D-glyceraldehyde_3-phosphate + pyruvate
|
4.1.2.14
2-dehydro-3-deoxy-phosphogluconate aldolase
4.1.2.21
2-dehydro-3-deoxy-6-phosphogalactonate aldolase
4.1.2.55
2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
|
–
–
–
|
|
BRENDA:
BR353
KEGG:
R01064
MetaCyc:
DEHYDDEOXPHOSGALACT-ALDOL-RXN
|
|
|
|
dolichyl_phosphate + H2O <=> dolichol + phosphate
|
3.1.3.51
dolichyl-phosphatase
|
–
|
|
BRENDA:
BR15945
KEGG:
R01003
MetaCyc:
DOLICHYL-PHOSPHATASE-RXN
|
|
|
|
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-idosamine + acetyl-CoA <=> UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-idose + CoA + H+
|
2.3.1
|
–
|
|
KEGG:
R12561
MetaCyc:
RXN-17081
|
|
|
|
7,9,12-Decaketide_intermediate_2 <=> 7,9,12-Decaketide_intermediate_3 + 2 H2O
|
4.2.1
|
–
|
|
KEGG:
R09266
|
|
|
|
pre-queuine_1 + NADP+ <=> 7-cyano-7-carbaguanine + NADPH + H+
|
1.7.1.13
preQ1 synthase
|
–
|
|
BRENDA:
BR48717
KEGG:
R07605
MetaCyc:
RXN0-4022
SABIO-RK:
13537
|
|
|
|
NAD+ + meso-tartrate <=> H+ + NADH + Dihydroxyfumarate
|
1.3.1.7
meso-tartrate dehydrogenase
|
–
|
|
BRENDA:
BR33781
KEGG:
R02544
MetaCyc:
MESO-TARTRATE-DEHYDROGENASE-RXN
SABIO-RK:
440
|
|
|
|
alpha-D-glucose_6-phosphate <=> beta-D-fructose_6-phosphate
|
5.3.1.9
glucose-6-phosphate isomerase
|
–
|
|
KEGG:
R02740
|
|
|
|
dTDP-4-dehydro-6-deoxy-D-glucose <=> dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose + H2O
|
4.2.1.159
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose 2,3-dehydratase
|
–
|
|
BRENDA:
BR51535
KEGG:
R05518
MetaCyc:
RXN-16567
|
|
|
|
(2S)-lactyl-2-diphospho-5''-guanosine + coenzyme_F0 <=> GMP + coenzyme_F420-0
|
2.7.8.28
2-phospho-L-lactate transferase
|
–
|
|
BRENDA:
BR49191;
BR53128
KEGG:
R09398
SABIO-RK:
13518
|
|
|
|
Dihydroxyfumarate <=> Oxaloglycolate
|
not assigned
|
–
|
|
KEGG:
R03128
SABIO-RK:
2963
|
|
|
|
tetracycline + O2 + Cl- + FADH2 <=> 7-chlorotetracycline + H2O + FAD + H+
|
1.14.19.49
tetracycline 7-halogenase
|
–
|
|
BRENDA:
BR51837
KEGG:
R11478
MetaCyc:
RXN-17996
|
|
|
|
7,8-dihydroneopterin_3''-triphosphate <=> 6-pyruvoyltetrahydropterin + tripolyphosphate + H+
|
4.2.3.12
6-pyruvoyltetrahydropterin synthase
|
–
|
|
BRENDA:
BR48350
KEGG:
R04286
MetaCyc:
4.2.3.12-RXN
SABIO-RK:
9435
|
|
|
|
2-Hydroxy-2H-benzo[h]chromene-2-carboxylate <=> cis-4-(1''-Hydroxynaphth-2''-yl)-2-oxobut-3-enoate
|
5.1.2
|
–
|
|
KEGG:
R05642
|
|
|
|
glycine + acceptor <=> cyanide + CO2 + reduced_acceptor
|
1.4.99.5
glycine dehydrogenase (cyanide-forming)
|
–
|
|
BRENDA:
BR36887
KEGG:
R00374;
R05704
MetaCyc:
1.4.99.5-RXN
|
|
|
|
7,9,12-Decaketide_intermediate_1 + NADPH + H+ <=> 7,9,12-Decaketide_intermediate_2 + NADP+
|
1.1.1
|
–
|
|
KEGG:
R09263
|
|
|
|
tryprostatin_A + reduced_flavodoxin + O2 <=> fumitremorgin_C + flavin + 2 H2O
|
1.14.19.71
fumitremorgin C synthase
|
–
|
|
BRENDA:
BR50590
KEGG:
R10416
|
|
|
|
4-Methylbenzoate + O2 + NADH + H+ <=> cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NAD+
|
1.14.12
|
–
|
|
KEGG:
R05290
|
|
|
|
normetanephrine + H2O + O2 <=> 4-hydroxyphenyl-3-methoxyglycolaldehyde + NH3 + H2O2
|
1.4.3.4
monoamine oxidase
|
–
|
|
KEGG:
R04893
MetaCyc:
RXN-10910
|
|
|
|
UDP-N-acetyl-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn <=> UDP + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)-[beta-D-GlcNAc-(1->4)-[beta-D-GlcNAc-(1->2)]-alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-1-Asn
|
2.4.1.145
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
|
–
|
|
KEGG:
R05987
|
|
|
|
galactarate <=> 5-dehydro-4-deoxy-D-glucarate + H2O
|
4.2.1.42
galactarate dehydratase
|
–
|
|
BRENDA:
BR421
KEGG:
R05608
MetaCyc:
GALACTARDEHYDRA-RXN
|
|
|
|
glutathione + ROOH <=> GSSG + H2O + an_alcohol
|
1.11.1.27
glutathione-dependent peroxiredoxin
1.11.1.9
glutathione peroxidase
|
–
–
|
|
BRENDA:
BR53022
KEGG:
R12578
MetaCyc:
RXN-20693
|
|
|
|
GDP-L-fucose + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-beta-D-GlcNAc-1-Asn <=> GDP + alpha-D-Man-(1->6)-[alpha-D-Man-(1->3)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-[beta-D-Gal-(1->4)-alpha-L-Fuc-(1->6)]-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-1-Asn
|
2.4.1
|
–
|
|
KEGG:
R09324
|
|
|
|
ATP + L-lysine + beta-Alanine <=> ADP + phosphate + beta-Ala-Lys
|
6.3.2.11
carnosine synthase
|
–
|
|
KEGG:
R00910
|
|
|
|
H2O + 1D-myo-inositol_1,4,5-trisphosphate <=> D-myo-inositol_(1,4)-bisphosphate + phosphate
|
3.1.3.36
phosphoinositide 5-phosphatase
3.1.3.56
inositol-polyphosphate 5-phosphatase
|
–
–
|
|
BRENDA:
BR48156;
BS390571
KEGG:
R03394
MetaCyc:
3.1.3.56-RXN
SABIO-RK:
3198
|
|
|
|
7-chloro-L-tryptophan + O2 <=> 2-imino-3-(7-chloroindol-3-yl)propanoate + H2O2 + H+
|
1.4.3.23
7-chloro-L-tryptophan oxidase
|
–
|
|
BRENDA:
BR49130
KEGG:
R09560
MetaCyc:
RXN-10843
|
|
|
|
protein_Npi-phospho-L-histidine + D-glucose <=> protein_L-histidine + alpha-D-glucose_6-phosphate
|
2.7.1.199
protein-Npi-phosphohistidine---D-glucose phosphotransferase
|
–
|
|
KEGG:
R02738
SABIO-RK:
12
|
|
|
|
uridine_3''-monophosphate + H2O <=> uridine + phosphate
|
3.1.3.1
alkaline phosphatase
3.1.3.2
acid phosphatase
3.1.3.25
inositol-phosphate phosphatase
3.1.3.31
nucleotidase
3.1.3.6
3'-nucleotidase
3.1.30.1
Aspergillus nuclease S1
3.1.4.16
2',3'-cyclic-nucleotide 2'-phosphodiesterase
|
–
–
–
–
–
–
–
|
|
BRENDA:
BS64626
KEGG:
R01877
MetaCyc:
RXN-14115
SABIO-RK:
487
|
|
|
|
Caffeine + NADPH + O2 + H+ <=> paraxanthine + NADP+ + formaldehyde + H2O
|
1.14.13.128
7-methylxanthine demethylase
1.14.13.179
methylxanthine N3-demethylase
1.14.14.1
unspecific monooxygenase
|
–
–
–
|
|
BRENDA:
BS417832
KEGG:
R07939
MetaCyc:
RXN-13106
|
|
|
|
D-glyceraldehyde + H2O + oxidized_ferredoxin <=> D-glycerate + H+ + reduced_ferredoxin
|
1.2.7.5
aldehyde ferredoxin oxidoreductase
|
–
|
|
KEGG:
R08571
|
|
|
|
GDP-L-fucose + Galactosylgloboside <=> Globo-H + GDP + H+
|
2.4.1
2.4.1.69
type 1 galactoside alpha-(1,2)-fucosyltransferase
|
–
–
|
|
KEGG:
R05968
MetaCyc:
RXN-18300
|
|
|
|
5-oxopent-3-ene-1,2,5-tricarboxylate + H+ <=> 2-hydroxyhepta-2,4-dienedioate + CO2
|
4.1.1.68
5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase
|
–
|
|
BRENDA:
BS422664
KEGG:
R04380
|
|
|
|
formate + coenzyme_F420 + H+ <=> CO2 + reduced_coenzyme_F420
|
1.17.1.9
formate dehydrogenase
1.17.98.3
formate dehydrogenase (coenzyme F420)
|
–
–
|
|
BRENDA:
BR51102
KEGG:
R10797
MetaCyc:
RXN-15617
SABIO-RK:
11358;
11359
|
|
|
|
acyl-[acyl-carrier_protein] + phosphate <=> acyl_phosphate + [acyl-carrier_protein]
|
2.3.1.274
phosphate acyltransferase
|
–
|
|
BRENDA:
BR52533
KEGG:
R12240
MetaCyc:
RXN-9590
|
|
|
|
ATP + (25R)-3alpha,7alpha-dihydroxy-5-beta-cholestanate + CoA <=> AMP + diphosphate + 3alpha,7alpha-dihydroxy-5beta-cholestanoyl-CoA
|
6.2.1.28
3alpha,7alpha-dihydroxy-5beta-cholestanate---CoA ligase
6.2.1.7
cholate---CoA ligase
|
–
–
|
|
BRENDA:
BR80;
BS273
KEGG:
R04507;
R08738
MetaCyc:
6.2.1.28-RXN
|
|
|
|
S-adenosyl-L-methionine + 8-demethyl-8-(2-O-methyl-alpha-L-rhamnosyl)-tetracenomycin_C <=> 8-demethyl-8-(2,3-O-dimethyl-alpha-L-rhamnosyl)-tetracenomycin_C + S-adenosyl-L-homocysteine + H+
|
2.1.1.306
8-demethyl-8-(2-methoxy-alpha-L-rhamnosyl)tetracenomycin-C 3'-O-methyltransferase
|
–
|
|
BRENDA:
BR50858
KEGG:
R10957
MetaCyc:
RXN-15404
|
|
|
|
3,5-diphosphomevalonate + H+ <=> isopentenyl_phosphate + CO2 + phosphate
|
4.1.1.110
bisphosphomevalonate decarboxylase
|
–
|
|
BRENDA:
BR52424
KEGG:
R10781
MetaCyc:
RXN-15649
|
|
|
|
L-arogenate + NAD+ <=> L-tyrosine + CO2 + NADH
|
1.3.1.12
prephenate dehydrogenase
1.3.1.43
arogenate dehydrogenase
1.3.1.78
arogenate dehydrogenase (NADP+)
1.3.1.79
arogenate dehydrogenase [NAD(P)+]
|
–
–
–
–
|
|
BRENDA:
BR36825
KEGG:
R00732
MetaCyc:
CYCLOHEXADIENYL-DEHYDROGENASE-RXN;
RXN-14476_WOP
SABIO-RK:
1095
|
|
|
|
alpha-D-GlcN-(1->6)-Ino-P + H2O <=> Glucosaminyl-alpha-1,6-D-myo-inositol + phosphatidic_acid
|
3.1.4.50
glycosylphosphatidylinositol phospholipase D
|
–
|
|
KEGG:
R06623
|
|
|
|
S-methyl-5''-thioadenosine + phosphate <=> adenine + S-methyl-5-thio-alpha-D-ribose_1-phosphate
|
2.4.2.1
purine-nucleoside phosphorylase
2.4.2.28
S-methyl-5'-thioadenosine phosphorylase
3.2.2.9
adenosylhomocysteine nucleosidase
|
–
–
–
|
|
BRENDA:
BR47472;
BS354415
KEGG:
R01402
MetaCyc:
5-METHYLTHIOADENOSINE-PHOSPHORYLASE-RXN
SABIO-RK:
1594
|
|
|
|
futalosine + H2O <=> dehypoxanthine_futalosine + hypoxanthine
|
3.2.2.26
futalosine hydrolase
|
–
|
|
BRENDA:
BR48967
KEGG:
R08587
MetaCyc:
RXN-9780
|
|
|
|
H+ + N-carbamoylsarcosine + H2O <=> NH3 + CO2 + sarcosine
|
3.5.1.59
N-carbamoylsarcosine amidase
|
–
|
|
BRENDA:
BR22703
KEGG:
R01563
MetaCyc:
N-CARBAMOYLSARCOSINE-AMIDASE-RXN
|
|
|
|
L-tyrosine + O2 + reduced_flavodoxin <=> N-hydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
|
BRENDA:
BR36762
KEGG:
R00730
|
|
|
|
6-phospho-D-glucono-1,5-lactone + H2O <=> H+ + 6-phosphogluconate
|
3.1.1.31
6-phosphogluconolactonase
|
–
|
|
BRENDA:
BR10654
KEGG:
R02035
MetaCyc:
6PGLUCONOLACT-RXN
SABIO-RK:
109
|
|
|
|
1alpha,25-dihydroxyvitamin_D3 + reduced_adrenodoxin + O2 + H+ <=> 1alpha,24R,25-trihydroxyvitamin_D3 + oxidized_ferredoxin + H2O
|
1.14.15.16
vitamin D3 24-hydroxylase
|
–
|
|
BRENDA:
BR49597
KEGG:
R09515
MetaCyc:
RXN-9830
|
|
|
|
4-oxo-4-(pyridin-3-yl)butanal + H2O + NADP+ <=> 4-oxo-4-(pyridin-3-yl)butanoate + NADPH + H+
|
1.2.1.83
3-succinoylsemialdehyde-pyridine dehydrogenase
|
–
|
|
BRENDA:
BR50147
KEGG:
R10105
MetaCyc:
RXN-13089
|
|
|
|
pyridoxine + O2 <=> pyridoxal + H2O2
|
1.1.3.12
pyridoxine 4-oxidase
1.4.3.5
pyridoxal 5'-phosphate synthase
|
–
–
|
|
BRENDA:
BR36730
KEGG:
R01711
MetaCyc:
PYRIDOXINE-4-OXIDASE-RXN
|
|
|
|
gamma-butyrobetaine + 2-oxoglutarate + O2 <=> L-carnitine + succinate + CO2
|
1.14.11.1
gamma-butyrobetaine dioxygenase
|
–
|
|
BRENDA:
BR40459
KEGG:
R02397
MetaCyc:
1.14.11.1-RXN
SABIO-RK:
2337;
6990
|
|
|
|
Hygrine <=> tropinone
|
not assigned
|
–
|
|
KEGG:
R06733
|
|
|
|
isovaleryl-CoA + FAD <=> 3-methylcrotonoyl-CoA + FADH2
|
1.3.8.4
isovaleryl-CoA dehydrogenase
1.3.8.7
medium-chain acyl-CoA dehydrogenase
|
–
–
|
|
BRENDA:
BS424839
KEGG:
R04095
SABIO-RK:
3822
|
|
|
|
4-(glutamylamino)_butanoate + H2O <=> L-glutamate + 4-aminobutanoate
|
3.5.1.94
gamma-glutamyl-gamma-aminobutyrate hydrolase
|
–
|
|
BRENDA:
BR48700
KEGG:
R07419
MetaCyc:
RXN0-3942
|
|
|
|
guanosine + H2O <=> D-ribose + guanine
|
3.2.2.1
purine nucleosidase
3.2.2.2
inosine nucleosidase
3.2.2.7
adenosine nucleosidase
3.2.2.8
ribosylpyrimidine nucleosidase
|
–
–
–
–
|
|
BRENDA:
BS214500
KEGG:
R01677
MetaCyc:
RXN0-366
SABIO-RK:
321
|
|
|
|
dCTP + thioredoxin_disulfide + H2O <=> CTP + thioredoxin
|
1.17.4.1
ribonucleoside-diphosphate reductase
1.17.4.2
ribonucleoside-triphosphate reductase (thioredoxin)
|
–
–
|
|
BRENDA:
BS287789
KEGG:
R02022
MetaCyc:
RXN-21264
SABIO-RK:
491
|
|
|
|
O-acetyl-L-serine + Hydroxyurea <=> O-ureido-L-serine + acetate + H+
|
2.5.1.51
beta-pyrazolylalanine synthase
2.6.99.3
O-ureido-L-serine synthase
|
–
–
|
|
BRENDA:
BR50676
KEGG:
R10461
MetaCyc:
RXN-14458
|
|
|
|
[glycine_cleavage_system_H]-N6-octanoyl-L-lysine + Lipoyl-carrier_protein_E2 <=> glycine_cleavage_system_H + [Lipoyl-carrier_protein_E2]-N6-octanoyl-L-lysine
|
2.3.1.204
octanoyl-[GcvH]:protein N-octanoyltransferase
|
–
|
|
KEGG:
R12425
|
|
|
|
citrate <=> isocitrate
|
4.2.1.3
aconitate hydratase
|
–
|
|
BRENDA:
BS18704
KEGG:
R01324
MetaCyc:
RXN-14047
SABIO-RK:
272
|
|
|
|
beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> |