|
|
L-aspartate + L-citrulline + ATP <=> H+ + argininosuccinate + diphosphate + AMP
|
6.3.4.5
argininosuccinate synthase
|
–
|
|
BRENDA:
BR142;
BS408483
KEGG:
R01954
MetaCyc:
ARGSUCCINSYN-RXN
SABIO-RK:
572
|
|
|
|
L-ornithine + Carbamoyl_phosphate <=> H+ + L-citrulline + phosphate
|
2.1.3.3
ornithine carbamoyltransferase
2.1.3.6
putrescine carbamoyltransferase
3.5.3.12
agmatine deiminase
|
–
–
–
|
|
BRENDA:
BR43950;
BS140887
KEGG:
R01398
MetaCyc:
ORNCARBAMTRANSFER-RXN;
RXN-13482
SABIO-RK:
98
|
|
|
|
argininosuccinate <=> L-arginine + fumarate
|
4.3.2.1
argininosuccinate lyase
4.3.2.2
adenylosuccinate lyase
|
–
–
|
|
BRENDA:
BR3431
KEGG:
R01086
MetaCyc:
ARGSUCCINLYA-RXN
SABIO-RK:
573
|
|
|
|
ATP + L-glutamine + HCO3- + H2O <=> L-glutamate + Carbamoyl_phosphate + ADP + phosphate + H+
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
|
BRENDA:
BR152
KEGG:
R00575
MetaCyc:
CARBPSYN-RXN
SABIO-RK:
203
|
|
|
|
[amino_group_carrier_protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate + 2-oxoglutarate <=> L-glutamate + LysW-L-glutamate_5-semialdehyde
|
2.6.1
2.6.1.11
acetylornithine transaminase
|
–
–
|
|
KEGG:
R10932
MetaCyc:
RXN-15007
|
|
|
|
L-glutamate + [amino_group_carrier_protein]-C-terminal-L-glutamate + ATP <=> LysW-L-glutamate + ADP + phosphate + H+
|
6.3.2.M4
|
–
|
|
MetaCyc:
RXN-15003
|
|
|
|
LysW-L-glutamate_5-semialdehyde + NADP+ + phosphate <=> [amino-group_carrier_protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + NADPH + H+
|
1.2.1.38
N-acetyl-gamma-glutamyl-phosphate reductase
|
–
|
|
MetaCyc:
RXN-15006
|
|
|
|
[amino_group_carrier_protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate + H2O <=> L-ornithine + [amino_group_carrier_protein]-C-terminal-L-glutamate
|
3.5.1.132
[amino group carrier protein]-ornithine hydrolase
3.5.1.al
|
–
–
|
|
BRENDA:
BR52906
MetaCyc:
RXN-15004
|
|
|
|
LysW-L-glutamate + ATP <=> [amino-group_carrier_protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + ADP
|
2.7.2.8
acetylglutamate kinase
|
–
|
|
MetaCyc:
RXN-15005
|
|