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Glycosaminoglycan degradation

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
dermatan_sulfate + H2O <=> dermatan_sulfate + alpha-L-IdoA2S-(1->3)-beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S 3.2

beta-D-GlcA-(1->3)-beta-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-D-GlcNAc + H2O <=> beta-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-D-GlcNAc + D-glucuronate 3.2.1.31 beta-glucuronidase

beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + H2O <=> beta-D-Gal-(1->4)-D-GlcNAc-6-S + N-acetyl-D-glucosamine 3.2.1.52 beta-N-acetylhexosaminidase

beta-D-Gal6S-(1->4)-beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + H2O <=> beta-D-Gal-(1->4)-beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + sulfate 3.1.6.4 N-acetylgalactosamine-6-sulfatase

beta-D-GlcA-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> alpha-D-GlcNAc6S-(1->4)-D-GlcA + D-glucuronate 3.2.1.31 beta-glucuronidase

alpha-L-IdoA2S-(1->4)-alpha-D-GlcN2S-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> alpha-L-IdoA-(1->4)-alpha-D-GlcN2S-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + sulfate 3.1.6.13 iduronate-2-sulfatase

beta-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-D-GlcNAc + H2O <=> beta-D-GlcA-(1->3)-D-GlcNAc + N-acetyl-D-glucosamine 3.2.1.52 beta-N-acetylhexosaminidase

beta-D-Gal-(1->4)-beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + H2O <=> beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + D-galactose 3.2.1.23 beta-galactosidase

alpha-L-IdoA-(1->4)-alpha-D-GlcN2S-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> alpha-D-GlcN2S-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + L-iduronate 3.2.1.76 L-iduronidase

alpha-L-IdoA-(1->3)-beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + H2O <=> beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + L-iduronate 3.2.1.76 L-iduronidase

alpha-D-GlcN2S-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> alpha-D-GlcN-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + sulfate 3.10.1.1 N-sulfoglucosamine sulfohydrolase

beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + H2O <=> chondroitin_4-sulfate + N-acetyl-D-galactosamine 3.2.1.35 hyaluronoglucosaminidase

beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + H2O <=> chondroitin_4-sulfate + N-acetylgalactosamine_4-sulfate 3.2.1.35 hyaluronoglucosaminidase

heparan_sulfate + H2O <=> heparan_sulfate + alpha-L-IdoA2S-(1->4)-alpha-D-GlcN2S-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA 3.2.1
3.2.1.166 heparanase


beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + H2O <=> beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + sulfate 3.1.6.14 N-acetylglucosamine-6-sulfatase

Keratan_sulfate + H2O <=> Keratan_sulfate + beta-D-Gal6S-(1->4)-beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S 3.2.1.103 keratan-sulfate endo-1,4-beta-galactosidase

alpha-L-IdoA2S-(1->3)-beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + H2O <=> alpha-L-IdoA-(1->3)-beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + sulfate 3.1.6.13 iduronate-2-sulfatase

alpha-D-GlcNAc-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + N-acetyl-D-glucosamine 3.2.1.50 alpha-N-acetylglucosaminidase

beta-D-GalNAc4S-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + H2O <=> beta-D-GalNAc-(1->4)-beta-D-GlcA-(1->3)-D-GalNAc-4-S + sulfate 3.1.6.12 N-acetylgalactosamine-4-sulfatase

alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> alpha-D-GlcNAc-(1->4)-D-GlcA + sulfate 3.1.6.14 N-acetylglucosamine-6-sulfatase

beta-D-GlcNAc6S-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc-6-S + H2O <=> beta-D-Gal-(1->4)-D-GlcNAc-6-S + N-acetylglucosamine_6-sulfate 3.2.1.52 beta-N-acetylhexosaminidase

acetyl-CoA + alpha-D-GlcN-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA <=> CoA + alpha-D-GlcNAc-(1->4)-beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA 2.3.1.78 heparan-alpha-glucosaminide N-acetyltransferase

hyaluronic_acid + H2O <=> hyaluronic_acid + beta-D-GlcA-(1->3)-beta-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-D-GlcNAc 3.2.1.35 hyaluronoglucosaminidase

beta-D-GlcA2S-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + H2O <=> beta-D-GlcA-(1->4)-alpha-D-GlcNAc6S-(1->4)-D-GlcA + sulfate 3.1.6.18 glucuronate-2-sulfatase

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