|
|
2-Fluorobenzoate + NADH + H+ + O2 <=> 6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
|
1.14.12.10
benzoate 1,2-dioxygenase
|
–
|
| |
KEGG:
R08101
|
|
|
|
3,5-Dibromo-4-hydroxybenzamide + H2O <=> 3,5-dibromo-4-hydroxybenzoic_acid + NH3
|
3.5.1
|
–
|
| |
KEGG:
R07782
|
|
|
|
3-Fluorobenzoate + NADH + O2 + H+ <=> 3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
|
1.14.12.10
benzoate 1,2-dioxygenase
|
–
|
| |
KEGG:
R08108
|
|
|
|
3,5-dibromo-4-hydroxybenzonitrile + H2O <=> 3,5-Dibromo-4-hydroxybenzamide
|
4.2.1.84
nitrile hydratase
|
–
|
| |
KEGG:
R07780
|
|
|
|
ATP + 4-Fluorobenzoate + CoA <=> AMP + diphosphate + 4-fluorobenzoyl-CoA
|
6.2.1.25
benzoate---CoA ligase
6.2.1.27
4-hydroxybenzoate---CoA ligase
6.2.1.32
anthranilate---CoA ligase
6.2.1.33
4-chlorobenzoate---CoA ligase
|
–
–
–
–
|
| |
BRENDA:
BS251
KEGG:
R08117
|
|
|
|
3-Fluorobenzoate + NADH + H+ + O2 <=> 5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
|
1.14.12.10
benzoate 1,2-dioxygenase
|
–
|
| |
KEGG:
R08109
|
|
|
|
4-fluorobenzoyl-CoA + H2O <=> 4-hydroxybenzoyl-CoA + F-
|
3.8.1.7
4-chlorobenzoyl-CoA dehalogenase
|
–
|
| |
BRENDA:
BS18481
KEGG:
R08118
|
|
|
|
3-fluoro-cis,cis-muconate <=> 4-fluoromuconolactone
|
5.5.1.1
muconate cycloisomerase
|
–
|
| |
BRENDA:
BS1242
KEGG:
R08116
|
|
|
|
2-Fluorobenzoate + NADH + H+ + O2 <=> 2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+
|
1.14.12.10
benzoate 1,2-dioxygenase
|
–
|
| |
KEGG:
R08100
|
|
|
|
3,5-dibromo-4-hydroxybenzonitrile + 2 NADPH + 2 H+ + O2 <=> 2,6-dibromo-p-hydroquinone + cyanide + 2 NADP+ + H2O
|
1.14.13.50
pentachlorophenol monooxygenase
|
–
|
| |
BRENDA:
BS288319
KEGG:
R07779
|
|
|
|
H2O + 3,5-dibromo-4-hydroxybenzonitrile <=> NH3 + 3,5-dibromo-4-hydroxybenzoic_acid
|
3.5.5.1
nitrilase
3.5.5.6
bromoxynil nitrilase
|
–
–
|
| |
BRENDA:
BR48304
KEGG:
R04349
MetaCyc:
3.5.5.6-RXN
|
|
|
|
4-chlorobenzoyl-CoA + Cl- + NADP+ <=> 2,4-dichlorobenzoyl-CoA + NADPH
|
1.21.1.2
2,4-dichlorobenzoyl-CoA reductase
|
–
|
| |
BRENDA:
BR29442
KEGG:
R05276
MetaCyc:
1.3.1.63-RXN
|
|
|
|
2-bromomaleylacetate + NADH <=> maleylacetate + NAD+ + Br-
|
1.3.1.32
maleylacetate reductase
|
–
|
| |
BRENDA:
BS258491
KEGG:
R07781
|
|
|
|
5-Fluoromuconolactone + H2O <=> maleylacetate + F-
|
3.1.1.45
carboxymethylenebutenolidase
|
–
|
| |
KEGG:
R08120
|
|
|
|
H2O + 4-chlorobenzoyl-CoA <=> H+ + Cl- + 4-hydroxybenzoyl-CoA
|
3.8.1.7
4-chlorobenzoyl-CoA dehalogenase
|
–
|
| |
BRENDA:
BR3357
KEGG:
R04101
MetaCyc:
3.8.1.7-RXN
SABIO-RK:
3828
|
|
|
|
2-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate <=> catechol
|
1.3.1
|
–
|
| |
KEGG:
R08122
|
|
|
|
4-fluoromuconolactone + H2O <=> maleylacetate + F-
|
3.1.1.45
carboxymethylenebutenolidase
|
–
|
| |
BRENDA:
BS364274
KEGG:
R08121
SABIO-RK:
7904
|
|
|
|
2,6-dibromophenol <=> 2,6-dibromo-p-hydroquinone
|
not assigned
|
–
|
| |
KEGG:
R07784
|
|
|
|
fluorobenzene + NADH + O2 + H+ <=> 4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+
|
1.14.12
|
–
|
| |
KEGG:
R08103
|
|
|
|
2-Chlorobenzoate + O2 + NADH + H+ <=> catechol + Cl- + CO2 + NAD+
|
1.14.12.13
2-halobenzoate 1,2-dioxygenase
|
–
|
| |
BRENDA:
BR40444
KEGG:
R01033
MetaCyc:
2-CHLOROBENZOATE-12-DIOXYGENASE-RXN
|
|
|
|
fluorobenzene + NADH + H+ + O2 <=> 1-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+
|
1.14.12
|
–
|
| |
KEGG:
R08104
|
|
|
|
1-Fluorocyclohexadiene-cis,cis-1,2-diol <=> catechol + F-
|
not assigned
|
–
|
| |
KEGG:
R08106
|
|
|
|
6-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate <=> 3-fluorocatechol
|
1.3.1
|
–
|
| |
KEGG:
R08123
|
|
|
|
3-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 3-fluorocatechol + NADH + CO2 + H+
|
1.3.1.25
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
|
–
|
| |
KEGG:
R08111
|
|
|
|
ATP + CoA + 4-Chlorobenzoate <=> diphosphate + AMP + 4-chlorobenzoyl-CoA
|
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.25
benzoate---CoA ligase
6.2.1.33
4-chlorobenzoate---CoA ligase
|
–
–
–
|
| |
BRENDA:
BR86
KEGG:
R03932
MetaCyc:
6.2.1.33-RXN
SABIO-RK:
3673
|
|
|
|
2,4-Dichlorobenzoate + CoA + ATP <=> 2,4-dichlorobenzoyl-CoA + AMP + diphosphate
|
6.2.1
|
–
|
| |
KEGG:
R05451
MetaCyc:
RXN-16776
|
|
|
|
4-Fluorocatechol + O2 <=> 3-fluoro-cis,cis-muconate
|
1.13.11.1
catechol 1,2-dioxygenase
|
–
|
| |
BRENDA:
BS260581
KEGG:
R08115
|
|
|
|
4-Fluorocyclohexadiene-cis,cis-1,2-diol + NAD+ <=> 4-Fluorocatechol + NADH + H+
|
1.3.1
|
–
|
| |
KEGG:
R08105
|
|
|
|
4-Fluorobenzoate + NADH + H+ + O2 <=> 4-fluoro-2-hydro-1,2-dihydroxybenzoate + NAD+
|
1.14.12.10
benzoate 1,2-dioxygenase
|
–
|
| |
KEGG:
R08110
|
|
|
|
3,5-dibromo-4-hydroxybenzoic_acid <=> 2,6-dibromophenol
|
not assigned
|
–
|
| |
KEGG:
R07783
|
|
|
|
2-fluoro-cis,cis-muconate + H+ <=> 5-Fluoromuconolactone
|
5.5.1.7
chloromuconate cycloisomerase
|
–
|
| |
KEGG:
R08119
MetaCyc:
RXN-10122
|
|
|
|
3-fluorocatechol + O2 <=> 2-fluoro-cis,cis-muconate + H+
|
1.13.11.1
catechol 1,2-dioxygenase
1.13.11.M6
|
–
–
|
| |
KEGG:
R08114
MetaCyc:
RXN-10118
|
|
|
|
2,6-dibromo-p-hydroquinone <=> 2-bromomaleylacetate
|
not assigned
|
–
|
| |
KEGG:
R07785
|
|
|
|
4-fluoro-2-hydro-1,2-dihydroxybenzoate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+
|
1.3.1.25
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
|
–
|
| |
KEGG:
R08113
|
|
|
|
5-Fluorocyclohexadiene-cis,cis-1,2-diol-1-carboxylate + NAD+ <=> 4-Fluorocatechol + NADH + CO2 + H+
|
1.3.1.25
1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
|
–
|
| |
KEGG:
R08112
|
|
