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Carbon metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
D-glucono-1,5-lactone + H2O <=> H+ + D-gluconate 3.1.1.17 gluconolactonase
3.1.1.35 dihydrocoumarin hydrolase
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succinate + NAD+ <=> fumarate + NADH + H+ 1.3.1.6 fumarate reductase (NADH)
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NADP+ + H2O + L-glutamate <=> NADPH + 2-oxoglutarate + NH3 + H+ 1.4.1.13 glutamate synthase (NADPH)
1.4.1.2 glutamate dehydrogenase
1.4.1.3 glutamate dehydrogenase [NAD(P)+]
1.4.1.4 glutamate dehydrogenase (NADP+)
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–
–
–
methanol + coenzyme_M <=> methyl-CoM + H2O 2.1.1.246 [methyl-Co(III) methanol-specific corrinoid protein]---coenzyme M methyltransferase
2.1.1.90 methanol---corrinoid protein Co-methyltransferase
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ATP + D-gluconate <=> H+ + 6-phosphogluconate + ADP 2.7.1.12 gluconokinase
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2-dehydro-3-deoxy-D-gluconate <=> D-glyceraldehyde + pyruvate 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase
4.1.2.20 2-dehydro-3-deoxyglucarate aldolase
4.1.2.51 2-dehydro-3-deoxy-D-gluconate aldolase
4.1.2.55 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
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(3S)-3-carboxy-3-hydroxypropanoyl-CoA + H2O <=> (S)-malate + CoA + H+ 3.1.2.30 (3S)-malyl-CoA thioesterase
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(R)-2-methylmalonyl-CoA <=> succinyl-CoA 5.4.99.2 methylmalonyl-CoA mutase
5.4.99.63 ethylmalonyl-CoA mutase
5.4.99.64 2-hydroxyisobutanoyl-CoA mutase
–
–
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acetyl-CoA + 4-hydroxybutyrate <=> acetate + 4-hydroxybutanoyl-CoA 2.8.3
2.8.3.1 propionate CoA-transferase
–
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alpha-D-glucose_6-phosphate <=> beta-D-fructose_6-phosphate 5.3.1.9 glucose-6-phosphate isomerase
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D-glucose + NAD+ <=> D-glucono-1,5-lactone + NADH + H+ 1.1.1.118 glucose 1-dehydrogenase (NAD+)
1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.121 aldose 1-dehydrogenase (NAD+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
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fumarate + coenzyme_M + coenzyme_B <=> succinate + CoM-S-S-CoB 1.3.4.1 fumarate reductase (CoM/CoB)
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Dimethylamine + coenzyme_M <=> methyl-CoM + methylamine 2.1.1.247 [methyl-Co(III) methylamine-specific corrinoid protein]---coenzyme M methyltransferase
2.1.1.249 dimethylamine---corrinoid protein Co-methyltransferase
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–
5,6,7,8-tetrahydromethanopterin + formylmethanofuran + H+ <=> 5-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran 2.3.1.101 formylmethanofuran---tetrahydromethanopterin N-formyltransferase
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(2S)-methylsuccinyl-CoA + flavin <=> 2-methylfumaryl-CoA + reduced_flavodoxin 1.3.8.12 (2S)-methylsuccinyl-CoA dehydrogenase
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sedoheptulose_7-phosphate + D-glyceraldehyde_3-phosphate <=> beta-D-fructose_6-phosphate + D-erythrose_4-phosphate 2.2.1.1 transketolase
2.2.1.2 transaldolase
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glycine + 2-oxoglutarate <=> glyoxylate + L-glutamate 2.6.1.2 alanine transaminase
2.6.1.4 glycine transaminase
2.6.1.42 branched-chain-amino-acid transaminase
2.6.1.44 alanine---glyoxylate transaminase
2.6.1.48 5-aminovalerate transaminase
2.6.1.60 aromatic-amino-acid---glyoxylate transaminase
2.6.1.7 kynurenine---oxoglutarate transaminase
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D-erythrose_4-phosphate + D-xylulose_5-phosphate <=> beta-D-fructose_6-phosphate + D-glyceraldehyde_3-phosphate 2.2.1.1 transketolase
2.2.1.3 formaldehyde transketolase
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coenzyme_B + coenzyme_M + coenzyme_F420 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ <=> CoM-S-S-CoB + reduced_coenzyme_F420 + oxidized_ferredoxin 1.8.98.4 coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase
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beta-methylmalyl-CoA <=> glyoxylate + propionyl-CoA 4.1.3.24 malyl-CoA lyase
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methane + hydroquinone + O2 <=> methanol + 1,4-benzoquinone + H2O 1.14.18.3 methane monooxygenase (particulate)
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succinate + GTP + CoA <=> succinyl-CoA + GDP + phosphate 6.2.1.4 succinate---CoA ligase (GDP-forming)
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(S)-malate <=> fumarate + H2O 4.2.1.2 fumarate hydratase
4.2.1.34 (S)-2-methylmalate dehydratase
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5,10-methylenetetrahydrofolate + NADP+ <=> 5,10-methenyltetrahydrofolate + NADPH 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+)
1.5.1.5 methylenetetrahydrofolate dehydrogenase (NADP+)
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D-glyceraldehyde + H2O + oxidized_ferredoxin <=> D-glycerate + H+ + reduced_ferredoxin 1.2.7.5 aldehyde ferredoxin oxidoreductase
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CO + H2O + oxidized_ferredoxin <=> CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.2.7.4 anaerobic carbon monoxide dehydrogenase
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formate + coenzyme_F420 + H+ <=> CO2 + reduced_coenzyme_F420 1.17.1.9 formate dehydrogenase
1.17.98.3 formate dehydrogenase (coenzyme F420)
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oxidized_ferredoxin + formylmethanofuran + H2O <=> reduced_ferredoxin_[iron-sulfur]_cluster + methanofuran + CO2 + H+ 1.2.7.12 formylmethanofuran dehydrogenase
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oxaloacetate + acetyl-CoA + phosphate + ADP <=> citrate + CoA + ATP 2.3.3.8 ATP citrate synthase
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2-phospho-D-glycerate <=> 3-phospho-D-glycerate 5.4.2.11 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)
5.4.2.12 phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
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D-glucose + NADP+ <=> D-glucono-1,5-lactone + NADPH + H+ 1.1.1.119 glucose 1-dehydrogenase (NADP+)
1.1.1.179 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming)
1.1.1.359 aldose 1-dehydrogenase [NAD(P)+]
1.1.1.360 glucose/galactose 1-dehydrogenase
1.1.1.424 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,4-lactone-forming)
1.1.1.47 glucose 1-dehydrogenase [NAD(P)+]
1.3.1.20 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
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L-serine <=> pyruvate + NH3 4.1.99.1 tryptophanase
4.1.99.2 tyrosine phenol-lyase
4.2.1.22 cystathionine beta-synthase
4.3.1.15 diaminopropionate ammonia-lyase
4.3.1.17 L-serine ammonia-lyase
4.3.1.18 D-serine ammonia-lyase
4.3.1.19 threonine ammonia-lyase
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formate + NAD+ <=> CO2 + NADH 1.17.1.10 formate dehydrogenase (NADP+)
1.17.1.9 formate dehydrogenase
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D-ribulose_5-phosphate <=> D-xylulose_5-phosphate 5.1.3.1 ribulose-phosphate 3-epimerase
5.3.1.34 D-erythrulose 4-phosphate isomerase
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NH3 + HCO3- + ATP <=> Carbamoyl_phosphate + ADP + H2O + H+ 2.7.2.2 carbamate kinase
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pyruvate + CoA + oxidized_ferredoxin <=> acetyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.2.7.1 pyruvate synthase
1.2.7.11 2-oxoacid oxidoreductase (ferredoxin)
1.2.7.7 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
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–
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(3S)-3-carboxy-3-hydroxypropanoyl-CoA <=> glyoxylate + acetyl-CoA 4.1.3.24 malyl-CoA lyase
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6-phospho-D-glucono-1,5-lactone + H2O <=> H+ + 6-phosphogluconate 3.1.1.31 6-phosphogluconolactonase
–
formaldehyde + NAD+ + H2O <=> formate + NADH + H+ 1.2.1.19 aminobutyraldehyde dehydrogenase
1.2.1.21 glycolaldehyde dehydrogenase
1.2.1.22 lactaldehyde dehydrogenase
1.2.1.24 succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.32 aminomuconate-semialdehyde dehydrogenase
1.2.1.46 formaldehyde dehydrogenase
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.65 salicylaldehyde dehydrogenase
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
–
–
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acetyl-CoA + tetrahydrosarcinapterin <=> CoA + 5-methyltetrahydrosarcinapterin + CO not assigned
 –
succinyl-CoA + acetate <=> succinate + acetyl-CoA 2.8.3.1 propionate CoA-transferase
2.8.3.18 succinyl-CoA:acetate CoA-transferase
2.8.3.8 acetate CoA-transferase
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–
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glycolate + O2 <=> glyoxylate + H2O2 1.1.3.13 alcohol oxidase
1.1.3.15 (S)-2-hydroxy-acid oxidase
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(2S)-ethylmalonyl-CoA + NADP+ <=> crotonyl-CoA + CO2 + NADPH 1.3.1.85 crotonyl-CoA carboxylase/reductase
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5,10-methylenetetrahydromethanopterin + coenzyme_F420 + H+ <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced_coenzyme_F420 1.5.98.1 methylenetetrahydromethanopterin dehydrogenase
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4-hydroxybutyrate + ATP + CoA <=> 4-hydroxybutanoyl-CoA + AMP + diphosphate 6.2.1.40 4-hydroxybutyrate---CoA ligase (AMP-forming)
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isocitrate + NAD+ <=> 2-oxoglutarate + CO2 + NADH 1.1.1.286 isocitrate---homoisocitrate dehydrogenase
1.1.1.41 isocitrate dehydrogenase (NAD+)
1.1.1.42 isocitrate dehydrogenase (NADP+)
1.1.1.87 homoisocitrate dehydrogenase
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–
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O2 + methanol <=> H2O2 + formaldehyde 1.1.3.13 alcohol oxidase
1.1.3.6 cholesterol oxidase
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citrate <=> isocitrate 4.2.1.3 aconitate hydratase
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(3S)-citramalyl-CoA <=> pyruvate + acetyl-CoA 2.3.1.182 (R)-citramalate synthase
4.1.3.25 (S)-citramalyl-CoA lyase
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–
S-hydroxymethylglutathione + NAD+ <=> S-formylglutathione + NADH + H+ 1.1.1
1.1.1.1 alcohol dehydrogenase
1.1.1.284 S-(hydroxymethyl)glutathione dehydrogenase
1.2.1.46 formaldehyde dehydrogenase
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–
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D-arabino-hex-3-ulose_6-phosphate <=> beta-D-fructose_6-phosphate 5.3.1.27 6-phospho-3-hexuloisomerase
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phosphate + acetyl-CoA <=> acetyl_phosphate + CoA 2.3.1.19 phosphate butyryltransferase
2.3.1.222 phosphate propanoyltransferase
2.3.1.8 phosphate acetyltransferase
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ATP + beta-D-fructose_6-phosphate <=> H+ + ADP + D-fructose_1,6-bisphosphate 2.7.1.105 6-phosphofructo-2-kinase
2.7.1.11 6-phosphofructokinase
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D-ribose_5-phosphate <=> D-ribulose_5-phosphate 5.3.1.6 ribose-5-phosphate isomerase
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propionyl-CoA + NADP+ <=> acryloyl-CoA + NADPH + H+ 1.3.1
1.3.1.84 acrylyl-CoA reductase (NADPH)
1.3.1.95 acrylyl-CoA reductase (NADH)
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pyruvate + CoA + NAD+ <=> acetyl-CoA + CO2 + NADH 1.2.1.aj
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
1.8.1.4 dihydrolipoyl dehydrogenase
2.3.1.12 dihydrolipoyllysine-residue acetyltransferase
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–
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ATP + beta-D-fructose_6-phosphate <=> H+ + ADP + D-fructose_1,6-bisphosphate 2.7.1.105 6-phosphofructo-2-kinase
2.7.1.11 6-phosphofructokinase
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bithionol + H2O <=> H+ + 3-hydroxypropionate + CoA 3.1.2.4 3-hydroxyisobutyryl-CoA hydrolase
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D-glyceraldehyde_3-phosphate + NADP+ + H2O <=> H+ + 3-phospho-D-glycerate + NADPH 1.2.1.89 D-glyceraldehyde dehydrogenase (NADP+)
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]
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5,10-methylenetetrahydromethanopterin + NADP+ <=> 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH 1.5.1
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L-threo-3-methylaspartate <=> L-glutamate 5.4.99.1 methylaspartate mutase
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Polyphosphate + alpha-D-glucose <=> Polyphosphate + alpha-D-glucose_6-phosphate 2.7.1.63 polyphosphate---glucose phosphotransferase
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sedoheptulose_1,7-diphosphate <=> dihydroxyacetone_phosphate + D-erythrose_4-phosphate 4.1.2.13 fructose-bisphosphate aldolase
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alpha-D-glucose + ADP <=> alpha-D-glucose_6-phosphate + AMP 2.7.1.147 ADP-specific glucose/glucosamine kinase
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2-keto-3-deoxy_phosphogluconate <=> D-glyceraldehyde_3-phosphate + pyruvate 4.1.2.14 2-dehydro-3-deoxy-phosphogluconate aldolase
4.1.2.20 2-dehydro-3-deoxyglucarate aldolase
4.1.2.51 2-dehydro-3-deoxy-D-gluconate aldolase
4.1.2.55 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase
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glycine + tetrahydrofolate + NAD+ <=> 5,10-methylenetetrahydrofolate + NH3 + CO2 + NADH 1.4.1.f
1.4.4.2 glycine dehydrogenase (aminomethyl-transferring)
1.8.1.4 dihydrolipoyl dehydrogenase
2.1.2.10 aminomethyltransferase
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(S)-malate + NADP+ <=> H+ + NADPH + oxaloacetate 1.1.1.299 malate dehydrogenase [NAD(P)+]
1.1.1.37 malate dehydrogenase
1.1.1.375 L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.81 hydroxypyruvate reductase
1.1.1.82 malate dehydrogenase (NADP+)
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coenzyme_B + coenzyme_M + methanophenazine <=> CoM-S-S-CoB + dihydromethanophenazine 1.8.98.1 dihydromethanophenazine:CoB-CoM heterodisulfide reductase
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trimethylamine + H2O + flavin <=> Dimethylamine + formaldehyde + reduced_flavodoxin 1.5.8.2 trimethylamine dehydrogenase
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isocitrate + NADP+ <=> 2-oxoglutarate + CO2 + NADPH 1.1.1.286 isocitrate---homoisocitrate dehydrogenase
1.1.1.41 isocitrate dehydrogenase (NAD+)
1.1.1.42 isocitrate dehydrogenase (NADP+)
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(S)-3-hydroxybutyryl-CoA + NADP+ <=> acetoacetyl-CoA + NADPH + H+ 1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
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methylamine + coenzyme_M <=> NH3 + methyl-CoM 2.1.1.247 [methyl-Co(III) methylamine-specific corrinoid protein]---coenzyme M methyltransferase
2.1.1.248 methylamine---corrinoid protein Co-methyltransferase
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D-glycerate + ATP <=> H+ + 2-phospho-D-glycerate + ADP 2.7.1.165 glycerate 2-kinase
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5,10-methenyltetrahydrofolate + H2O <=> 10-formyltetrahydrofolate + H+ 3.5.4.9 methenyltetrahydrofolate cyclohydrolase
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D-gluconate <=> H2O + 2-dehydro-3-deoxy-D-gluconate 4.2.1.140 gluconate/galactonate dehydratase
4.2.1.39 gluconate dehydratase
4.2.1.82 xylonate dehydratase
4.2.1.9 dihydroxy-acid dehydratase
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ATP + acetyl-CoA + HCO3- <=> ADP + phosphate + malonyl-CoA + H+ 6.4.1.2 acetyl-CoA carboxylase
6.4.1.3 propionyl-CoA carboxylase
6.4.1.4 methylcrotonoyl-CoA carboxylase
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L-threo-3-methylaspartate <=> NH3 + mesaconate 4.3.1.2 methylaspartate ammonia-lyase
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acetyl-CoA + H2O + glyoxylate <=> H+ + (S)-malate + CoA 2.3.3.9 malate synthase
4.1.3.1 isocitrate lyase
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acetyl-CoA + 5,6,7,8-tetrahydromethanopterin <=> CoA + 5-Methyl-5,6,7,8-tetrahydromethanopterin + CO not assigned
 –
(S)-malate + NADP+ <=> pyruvate + CO2 + NADPH 1.1.1.38 malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.39 malate dehydrogenase (decarboxylating)
1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.85 3-isopropylmalate dehydrogenase
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6-phosphogluconate + NADP+ <=> D-ribulose_5-phosphate + CO2 + NADPH 1.1.1.351 phosphogluconate dehydrogenase [NAD(P)+-dependent, decarboxylating]
1.1.1.44 phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating)
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succinate_semialdehyde + NADP+ + CoA <=> succinyl-CoA + NADPH + H+ 1.2.1.75 malonyl-CoA reductase (malonate semialdehyde-forming)
1.2.1.76 succinate-semialdehyde dehydrogenase (acylating)
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D-arabino-hex-3-ulose_6-phosphate <=> beta-D-fructose_6-phosphate 5.3.1.27 6-phospho-3-hexuloisomerase
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4-hydroxybutyrate + NAD+ <=> succinate_semialdehyde + NADH + H+ 1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.21 aldose reductase
1.1.1.61 4-hydroxybutyrate dehydrogenase
1.1.1.79 glyoxylate reductase (NADP+)
1.1.1.B47
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propionyl-CoA + O2 <=> acryloyl-CoA + H2O2 1.3.3.6 acyl-CoA oxidase
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D-erythrose_4-phosphate + D-xylulose_5-phosphate <=> beta-D-fructose_6-phosphate + D-glyceraldehyde_3-phosphate 2.2.1.1 transketolase
2.2.1.3 formaldehyde transketolase
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H2O2 <=> H2O + O2 1.11.1.10 chloride peroxidase
1.11.1.21 catalase-peroxidase
1.11.1.6 catalase
1.14.18.1 tyrosinase
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S-formylglutathione + H2O <=> H+ + formate + glutathione 3.1.1.56 methylumbelliferyl-acetate deacetylase
3.1.2.12 S-formylglutathione hydrolase
3.1.2.6 hydroxyacylglutathione hydrolase
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beta-D-fructose_6-phosphate + ADP <=> H+ + D-fructose_1,6-bisphosphate + AMP 2.7.1.146 ADP-specific phosphofructokinase
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3-hydroxypropionate + NADP+ <=> malonate_semialdehyde + NADPH + H+ 1.1.1
1.1.1.2 alcohol dehydrogenase (NADP+)
1.1.1.276 serine 3-dehydrogenase (NADP+)
1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)
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CoA + acetate + ATP <=> acetyl-CoA + diphosphate + AMP 6.2.1.1 acetate---CoA ligase
6.2.1.17 propionate---CoA ligase
6.2.1.36 3-hydroxypropionyl-CoA synthase
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glyoxylate + L-serine <=> Hydroxypyruvate + glycine 2.6.1.15 glutamine---pyruvate transaminase
2.6.1.35 glycine---oxaloacetate transaminase
2.6.1.4 glycine transaminase
2.6.1.44 alanine---glyoxylate transaminase
2.6.1.45 serine---glyoxylate transaminase
2.6.1.51 serine---pyruvate transaminase
2.6.1.60 aromatic-amino-acid---glyoxylate transaminase
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D-ribulose_5-phosphate + ATP <=> H+ + D-ribulose_1,5-bisphosphate + ADP 2.7.1.19 phosphoribulokinase
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3-hydroxypropionate + ATP + CoA <=> bithionol + AMP + diphosphate 6.2.1.17 propionate---CoA ligase
6.2.1.36 3-hydroxypropionyl-CoA synthase
6.2.1.40 4-hydroxybutyrate---CoA ligase (AMP-forming)
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trimethylamine + coenzyme_M <=> methyl-CoM + Dimethylamine 2.1.1.247 [methyl-Co(III) methylamine-specific corrinoid protein]---coenzyme M methyltransferase
2.1.1.250 trimethylamine---corrinoid protein Co-methyltransferase
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(3S)-citramalyl-CoA <=> 3-methylfumaryl-CoA + H2O 4.2.1.148 2-methylfumaryl-CoA hydratase
4.2.1.153 3-methylfumaryl-CoA hydratase
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2-dehydro-3-deoxy-D-gluconate + ATP <=> H+ + 2-keto-3-deoxy_phosphogluconate + ADP 2.7.1.178 2-dehydro-3-deoxyglucono/galactono-kinase
2.7.1.45 2-dehydro-3-deoxygluconokinase
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H2O + 2-Phosphoglycolate <=> glycolate + phosphate 3.1.3.18 phosphoglycolate phosphatase
3.1.3.2 acid phosphatase
3.1.3.29 N-acylneuraminate-9-phosphatase
3.1.3.71 2-phosphosulfolactate phosphatase
5.4.2.4 bisphosphoglycerate mutase
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ATP + NH3 + CO2 + H2O <=> ADP + phosphate + Carbamoyl_phosphate 6.3.4.16 carbamoyl-phosphate synthase (ammonia)
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
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phosphoenolpyruvate + CO2 <=> phosphate + oxaloacetate 4.1.1.31 phosphoenolpyruvate carboxylase
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dihydroxyacetone + ATP <=> H+ + dihydroxyacetone_phosphate + ADP 2.7.1.28 triokinase
2.7.1.29 glycerone kinase
2.7.1.30 glycerol kinase
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H2O + sedoheptulose_1,7-diphosphate <=> sedoheptulose_7-phosphate + phosphate 3.1.3.11 fructose-bisphosphatase
3.1.3.37 sedoheptulose-bisphosphatase
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3-phospho-D-glycerate + H+ <=> D-ribulose_1,5-bisphosphate + CO2 + H2O 4.1.1.39 ribulose-bisphosphate carboxylase
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5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 <=> 5,10-methylenetetrahydromethanopterin + H+ 1.12.98.2 5,10-methenyltetrahydromethanopterin hydrogenase
1.12.99.6 hydrogenase (acceptor)
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(S)-3-hydroxybutyryl-CoA + NAD+ <=> acetoacetyl-CoA + NADH + H+ 1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
1.1.1.36 acetoacetyl-CoA reductase
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bithionol <=> acryloyl-CoA + H2O 4.2.1
4.2.1.116 3-hydroxypropionyl-CoA dehydratase
4.2.1.17 enoyl-CoA hydratase
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L-aspartate + 2-oxoglutarate <=> oxaloacetate + L-glutamate 2.6.1.1 aspartate transaminase
2.6.1.19 4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2 alanine transaminase
2.6.1.39 2-aminoadipate transaminase
2.6.1.42 branched-chain-amino-acid transaminase
2.6.1.5 tyrosine transaminase
2.6.1.57 aromatic-amino-acid transaminase
2.6.1.75 cysteine-conjugate transaminase
2.6.1.78 aspartate---prephenate aminotransferase
2.6.1.79 glutamate---prephenate aminotransferase
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succinate + CoA + ATP <=> succinyl-CoA + ADP + phosphate 6.2.1.13 acetate---CoA ligase (ADP-forming)
6.2.1.4 succinate---CoA ligase (GDP-forming)
6.2.1.5 succinate---CoA ligase (ADP-forming)
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tetrahydrofolate + ATP + formate <=> 10-formyltetrahydrofolate + ADP + phosphate 6.3.4.3 formate---tetrahydrofolate ligase
–
3-hydroxypropionate + NAD+ <=> malonate_semialdehyde + NADH + H+ 1.1.1.298 3-hydroxypropionate dehydrogenase (NADP+)
1.1.1.31 3-hydroxyisobutyrate dehydrogenase
1.1.1.59 3-hydroxypropionate dehydrogenase
1.1.1.60 2-hydroxy-3-oxopropionate reductase
–
–
–
–
D-glyceraldehyde_3-phosphate + NAD+ + H2O <=> 3-phospho-D-glycerate + NADH + H+ 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
1.2.1.3 aldehyde dehydrogenase (NAD+)
1.2.1.5 aldehyde dehydrogenase [NAD(P)+]
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
1.2.1.90 glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]
–
–
–
–
–
–
coenzyme_B + coenzyme_M + oxidized_ferredoxin <=> CoM-S-S-CoB + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.8.7.3 ferredoxin:CoB-CoM heterodisulfide reductase
–
5-Methyl-5,6,7,8-tetrahydromethanopterin + coenzyme_F420 <=> 5,10-methylenetetrahydromethanopterin + reduced_coenzyme_F420 1.5.98.2 5,10-methylenetetrahydromethanopterin reductase
–
D-glyceraldehyde_3-phosphate + phosphate + NADP+ <=> 3-phospho-D-glyceroyl_phosphate + NADPH + H+ 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
1.2.1.59 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating)
1.2.1.9 glyceraldehyde-3-phosphate dehydrogenase (NADP+)
–
–
–
–
succinate + ITP + CoA <=> succinyl-CoA + IDP + phosphate 6.2.1.4 succinate---CoA ligase (GDP-forming)
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citrate + CoA + ATP <=> (3S)-citryl-CoA + ADP + phosphate 6.2.1.18 citrate---CoA ligase
–
2-phospho-D-glycerate <=> phosphoenolpyruvate + H2O 4.2.1.11 phosphopyruvate hydratase
–
2-oxoglutarate + CoA + oxidized_ferredoxin <=> succinyl-CoA + CO2 + reduced_ferredoxin_[iron-sulfur]_cluster + H+ 1.2.7.11 2-oxoacid oxidoreductase (ferredoxin)
1.2.7.3 2-oxoglutarate synthase
–
–
succinyl-CoA + (S)-malate <=> succinate + (3S)-3-carboxy-3-hydroxypropanoyl-CoA 2.8.3.18 succinyl-CoA:acetate CoA-transferase
2.8.3.22 succinyl-CoA---L-malate CoA-transferase
–
–
butyryl-CoA + FAD <=> crotonyl-CoA + FADH2 1.3.3.6 acyl-CoA oxidase
1.3.8.1 short-chain acyl-CoA dehydrogenase
1.3.8.4 isovaleryl-CoA dehydrogenase
1.3.8.7 medium-chain acyl-CoA dehydrogenase
1.3.99
–
–
–
–
–
O-acetyl-L-serine + Sulfide <=> L-cysteine + acetate + H+ 2.5.1.47 cysteine synthase
2.5.1.49 O-acetylhomoserine aminocarboxypropyltransferase
2.5.1.65 O-phosphoserine sulfhydrylase
4.2.1.22 cystathionine beta-synthase
4.2.1.50 pyrazolylalanine synthase
4.4.1.9 L-3-cyanoalanine synthase
–
–
–
–
–
–
L-serine + tetrahydrofolate <=> glycine + 5,10-methylenetetrahydrofolate + H2O 2.1.2.1 glycine hydroxymethyltransferase
–
D-fructose_1,6-bisphosphate <=> dihydroxyacetone_phosphate + D-glyceraldehyde_3-phosphate