|
|
C20819 <=> 2,3-Dihydrothienamycin
|
not assigned
|
–
|
| |
KEGG:
R10739
|
|
|
|
C20819 <=> beta-Lactam_NS5
|
not assigned
|
–
|
| |
KEGG:
R10743
|
|
|
|
Epithienamycin_F + 2-oxoglutarate + O2 <=> Epithienamycin_E + succinate + CO2 + H2O
|
1.14.20
|
–
|
| |
KEGG:
R10741
|
|
|
|
(5R)-carbapen-2-em-3-carboxylate + L-cysteine <=> C20817 + CO2
|
not assigned
|
–
|
| |
KEGG:
R10736
|
|
|
|
Epithienamycin_E + 2-oxoglutarate + O2 <=> MM_4550 + succinate + CO2
|
1.14.20
|
–
|
| |
KEGG:
R10742
|
|
|
|
H+ + L-pyrroline-5-carboxylate + malonyl-CoA + H2O <=> (2S,5S)-5-carboxymethylproline + CoA + CO2
|
2.3.1.226
carboxymethylproline synthase
|
–
|
| |
BRENDA:
BR50641
KEGG:
R10485
MetaCyc:
RXN-8947
SABIO-RK:
7117
|
|
|
|
C20821 + pantetheine <=> OA-6129_A
|
not assigned
|
–
|
| |
KEGG:
R10749
|
|
|
|
C20818 <=> C20822
|
not assigned
|
–
|
| |
KEGG:
R10753
|
|
|
|
L-proline + FAD <=> L-pyrroline-5-carboxylate + FADH2
|
1.5
1.5.5.2
proline dehydrogenase
1.5.8
1.5.99.B2
|
–
–
–
–
|
| |
BRENDA:
BS389060
KEGG:
R10507
MetaCyc:
RXN-21556
|
|
|
|
H+ + H2O + L-pyrroline-5-carboxylate <=> L-glutamate_5-semialdehyde
|
0.0.0.0
|
–
|
| |
BRENDA:
BR52883
KEGG:
R03314
MetaCyc:
SPONTPRO-RXN
|
|
|
|
C20822 <=> Northienamycin
|
not assigned
|
–
|
| |
KEGG:
R10756
|
|
|
|
OA-6129_A + 2-oxoglutarate + O2 <=> OA-6129_B2 + succinate + CO2
|
1.14.20
|
–
|
| |
KEGG:
R10735
|
|
|
|
(2S,5S)-5-carboxymethylproline + ATP <=> H+ + (3S,5S)-carbapenam_3-carboxylate + AMP + diphosphate
|
6.3.3.6
carbapenam-3-carboxylate synthase
|
–
|
| |
BRENDA:
BR50731
KEGG:
R10556
MetaCyc:
RXN-8948
|
|
|
|
C20817 <=> C20818
|
2.1.1
|
–
|
| |
KEGG:
R10737
|
|
|
|
L-glutamate + ATP <=> L-5-glutamyl_phosphate + ADP
|
2.7.2.11
glutamate 5-kinase
|
–
|
| |
BRENDA:
BR47821
KEGG:
R00239
MetaCyc:
GLUTKIN-RXN
SABIO-RK:
752
|
|
|
|
C20823 <=> C20819
|
not assigned
|
–
|
| |
KEGG:
R10755
|
|
|
|
beta-Lactam_NS5 <=> Thienamycin
|
not assigned
|
–
|
| |
KEGG:
R10744
|
|
|
|
Pantetheine_4''-phosphate + H2O <=> pantetheine + phosphate
|
3.1.3
|
–
|
| |
KEGG:
R10748
|
|
|
|
OA-6129_B2 <=> OA-6129_B1
|
not assigned
|
–
|
| |
KEGG:
R10750
|
|
|
|
CoA + H2O <=> adenosine_3,5''-bisphosphate + 4''-phosphopantetheine + H+
|
3.6.1
3.6.1.22
NAD+ diphosphatase
3.6.1.55
8-oxo-dGTP diphosphatase
3.6.1.M6
|
–
–
–
–
|
| |
KEGG:
R10747
MetaCyc:
RXN-10811
SABIO-RK:
14538
|
|
|
|
acetyl-CoA + Thienamycin <=> CoA + N-Acetylthienamycin
|
2.3.1
|
–
|
| |
KEGG:
R10745
|
|
|
|
(3S,5S)-carbapenam_3-carboxylate + 2-oxoglutarate + O2 <=> (5R)-carbapen-2-em-3-carboxylate + succinate + CO2 + H2O
|
1.14.20
1.14.20.3
(5R)-carbapenem-3-carboxylate synthase
|
–
–
|
| |
BRENDA:
BR50588
KEGG:
R10415
MetaCyc:
RXN-8949
|
|
|
|
C20822 <=> C20823
|
not assigned
|
–
|
| |
KEGG:
R10754
|
|
|
|
OA-6129_C + H2O <=> Deacetylepithienamycin_F + pantothenate
|
3.5.1
|
–
|
| |
KEGG:
R10752
|
|
|
|
2,3-Dihydrothienamycin + 2-oxoglutarate + O2 <=> Thienamycin + succinate + CO2 + H2O
|
1.14.20
|
–
|
| |
KEGG:
R10740
|
|
|
|
acetyl-CoA + Deacetylepithienamycin_F <=> CoA + Epithienamycin_F
|
2.3.1
|
–
|
| |
KEGG:
R10746
|
|
|
|
L-glutamate_5-semialdehyde + phosphate + NADP+ <=> L-5-glutamyl_phosphate + NADPH + H+
|
1.2.1.41
glutamate-5-semialdehyde dehydrogenase
|
–
|
| |
BRENDA:
BR36782
KEGG:
R03313
MetaCyc:
GLUTSEMIALDEHYDROG-RXN
SABIO-RK:
3127
|
|
|
|
3''-Phosphoadenylyl_sulfate + OA-6129_B1 <=> Adenosine_3'',5''-bisphosphate + OA-6129_C
|
2.8.2
|
–
|
| |
KEGG:
R10751
|
|
|
|
C20818 <=> C20819
|
2.1.1
|
–
|
| |
KEGG:
R10738
|
|
