|
|
adipyl-CoA + FAD <=> 2,3-dehydroadipyl-CoA + FADH2
|
1.3.99
|
–
|
| |
KEGG:
R06943
|
|
|
|
H2O + cyclohexyl_sulfamate <=> sulfate + Cyclohexylamine
|
3.10.1.2
cyclamate sulfohydrolase
|
–
|
| |
BRENDA:
BR22644
KEGG:
R02564
MetaCyc:
CYCLAMATE-SULFOHYDROLASE-RXN
|
|
|
|
6-oxohexanoate + H2O + NADP+ <=> H+ + adipate + NADPH
|
1.2.1.4
aldehyde dehydrogenase (NADP+)
1.2.1.63
6-oxohexanoate dehydrogenase
|
–
–
|
| |
BRENDA:
BR29419
KEGG:
R05099
MetaCyc:
6-OXOHEXANOATE-OXIDATION-RXN
|
|
|
|
1-Oxa-2-oxo-7-hydroxycycloheptane <=> 6-oxohexanoate + H+
|
not assigned
|
–
|
| |
KEGG:
R05098
MetaCyc:
RXN-14101
|
|
|
|
O2 + H2O + Cyclohexylamine <=> NH3 + H2O2 + cyclohexanone
|
1.4.3.12
cyclohexylamine oxidase
|
–
|
| |
BRENDA:
BR37108
KEGG:
R02233
MetaCyc:
CYCLOHEXYLAMINE-OXIDASE-RXN
|
|
|
|
N-(6-aminohexanoyl)n-6-aminohexanoate + H2O <=> N-(6-aminohexanoyl)-6-aminohexanoate
|
3.5.1.117
6-aminohexanoate-oligomer endohydrolase
3.5.1.46
6-aminohexanoate-oligomer exohydrolase
|
–
–
|
| |
KEGG:
R10976;
R10979
MetaCyc:
RXN-3963
|
|
|
|
Cyclohexanol + NAD+ <=> cyclohexanone + NADH + H+
|
1.1.1.1
alcohol dehydrogenase
1.1.1.112
indanol dehydrogenase
1.1.1.163
cyclopentanol dehydrogenase
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.243
carveol dehydrogenase
1.1.1.245
cyclohexanol dehydrogenase
1.1.1.71
alcohol dehydrogenase [NAD(P)+]
|
–
–
–
–
–
–
–
|
| |
BRENDA:
BR29281
KEGG:
R02229
MetaCyc:
CYCLOHEXANOL-DEHYDROGENASE-RXN
SABIO-RK:
8784
|
|
|
|
N-cyclohexylformamide <=> H2O + cyclohexyl_isocyanide
|
4.2.1.103
cyclohexyl-isocyanide hydratase
|
–
|
| |
BRENDA:
BR36962
KEGG:
R05771
MetaCyc:
4.2.1.103-RXN
|
|
|
|
(3S)-3-hydroxyadipyl-CoA <=> 2,3-dehydroadipyl-CoA + H2O
|
4.2.1.17
enoyl-CoA hydratase
|
–
|
| |
BRENDA:
BS417838
KEGG:
R06942
MetaCyc:
RXN-2425
|
|
|
|
6-hydroxyhexanoate + NAD+ <=> H+ + 6-oxohexanoate + NADH
|
1.1.1.258
6-hydroxyhexanoate dehydrogenase
|
–
|
| |
BRENDA:
BR26043
KEGG:
R05283
MetaCyc:
6-HYDROXYHEXANOATE-OXIDATION-RXN
|
|
|
|
N-cyclohexylformamide + H2O <=> Cyclohexylamine + formate
|
3.5.1
|
–
|
| |
KEGG:
R06940
|
|
|
|
6-aminohexanoate + 2-oxoglutarate <=> 6-oxohexanoate + L-glutamate
|
2.6.1.116
6-aminohexanoate aminotransferase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.48
5-aminovalerate transaminase
|
–
–
–
–
|
| |
BRENDA:
BR52922
KEGG:
R05507
MetaCyc:
R562-RXN
|
|
|
|
N-(6-aminohexanoyl)-6-aminohexanoate + H2O <=> 6-aminohexanoate
|
3.5.1.46
6-aminohexanoate-oligomer exohydrolase
|
–
|
| |
BRENDA:
BR19247
KEGG:
R00059
MetaCyc:
RXN-3962
|
|
|
|
6-amino-hexanoate_cyclic_dimer + H2O <=> N-(6-aminohexanoyl)-6-aminohexanoate
|
3.5.1.117
6-aminohexanoate-oligomer endohydrolase
3.5.2.12
6-aminohexanoate-cyclic-dimer hydrolase
|
–
–
|
| |
BRENDA:
BR26103
KEGG:
R03448;
R10978
MetaCyc:
3.5.2.12-RXN
|
|
|
|
2-Hydroxycyclohexan-1-one + NAD+ <=> 1,2-Cyclohexanedione + NADH + H+
|
1.1.1.174
cyclohexane-1,2-diol dehydrogenase
|
–
|
| |
KEGG:
R03278
|
|
|
|
6-hydroxyhexanoate + NADP+ <=> 6-oxohexanoate + NADPH + H+
|
1.1.1.2
alcohol dehydrogenase (NADP+)
|
–
|
| |
KEGG:
R05231
|
|
|
|
epsilon-Caprolactam + H2O <=> 6-aminohexanoate
|
3.5.2
|
–
|
| |
KEGG:
R05356
MetaCyc:
R561-RXN
|
|
|
|
epsilon-caprolactone + H2O <=> H+ + 6-hydroxyhexanoate
|
3.1.1
3.1.1.17
gluconolactonase
3.1.1.83
monoterpene epsilon-lactone hydrolase
|
–
–
–
|
| |
KEGG:
R03751
MetaCyc:
6-HEXANOLIDE-HYDROLYSIS-RXN
|
|
|
|
6-amino-hexanoate_cyclic_dimer + H2O <=> N-(6-aminohexanoyl)-6-aminohexanoate
|
3.5.1.117
6-aminohexanoate-oligomer endohydrolase
3.5.2.12
6-aminohexanoate-cyclic-dimer hydrolase
|
–
–
|
| |
BRENDA:
BR26103
KEGG:
R03448;
R10978
MetaCyc:
3.5.2.12-RXN
|
|
|
|
cis-1,2-Cyclohexanediol + NAD+ <=> 2-Hydroxycyclohexan-1-one + NADH
|
1.1.1.174
cyclohexane-1,2-diol dehydrogenase
|
–
|
| |
KEGG:
R06621
|
|
|
|
(3S)-3-hydroxyadipyl-CoA + NAD+ <=> H+ + 3-oxoadipyl-CoA + NADH
|
1.1.1.157
3-hydroxybutyryl-CoA dehydrogenase
1.1.1.35
3-hydroxyacyl-CoA dehydrogenase
|
–
–
|
| |
BRENDA:
BS417822
KEGG:
R06941
MetaCyc:
RXN0-2044
|
|
|
|
Cyclohexane + NADH + H+ + O2 <=> Cyclohexanol + NAD+ + H2O
|
1.14.13
1.14.13.25
methane monooxygenase (soluble)
1.14.15.3
alkane 1-monooxygenase
|
–
–
–
|
| |
BRENDA:
BS186758
KEGG:
R06945
|
|
|
|
2-Hydroxycyclohexan-1-one + O2 + NADPH + H+ <=> 1-Oxa-2-oxo-7-hydroxycycloheptane + H2O + NADP+
|
1.14.13.66
2-hydroxycyclohexanone 2-monooxygenase
|
–
|
| |
BRENDA:
BR664
KEGG:
R03281
MetaCyc:
1.14.13.66-RXN
|
|
|
|
cyclohexanone + NADPH + H+ + O2 <=> epsilon-caprolactone + NADP+ + H2O
|
1.14.13.16
cyclopentanone monooxygenase
1.14.13.22
cyclohexanone monooxygenase
1.14.13.92
phenylacetone monooxygenase
|
–
–
–
|
| |
BRENDA:
BR40431
KEGG:
R02231
MetaCyc:
CYCLOHEXANONE-MONOOXYGENASE-RXN
SABIO-RK:
2202
|
|
|
|
ATP + adipate + CoA <=> AMP + diphosphate + adipyl-CoA
|
6.2.1
6.2.1.14
6-carboxyhexanoate---CoA ligase
6.2.1.23
dicarboxylate---CoA ligase
|
–
–
–
|
| |
BRENDA:
BS238
KEGG:
R06944
|
|
|
|
1,2-Cyclohexanedione + H2O <=> 6-oxohexanoate + H+
|
3.7.1.11
cyclohexane-1,2-dione hydrolase
|
–
|
| |
BRENDA:
BR49123
KEGG:
R05100
MetaCyc:
RXN-11050
|
|
|
|
NAD+ + trans-1,2-cyclohexanediol <=> H+ + NADH + 2-Hydroxycyclohexan-1-one
|
1.1.1.174
cyclohexane-1,2-diol dehydrogenase
|
–
|
| |
BRENDA:
BR29234
KEGG:
R03279
MetaCyc:
CYCLOHEXANE-12-DIOL-DEHYDROGENASE-RXN
|
|
